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Search of human proteins with 59814247
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|59814247 budding uninhibited by benzimidazoles 1 beta [Homo
sapiens]
(1050 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|59814247 budding uninhibited by benzimidazoles 1 beta [Homo s... 2111 0.0
gi|4757878 budding uninhibited by benzimidazoles 1 [Homo sapiens] 119 1e-26
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 46 2e-04
gi|148746195 trichohyalin [Homo sapiens] 45 5e-04
gi|4758128 doublecortin-like kinase 1 [Homo sapiens] 44 6e-04
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 44 0.001
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 44 0.001
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 44 0.001
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 42 0.002
gi|18390344 ATR interacting protein isoform 2 [Homo sapiens] 42 0.004
gi|18390347 ATR interacting protein isoform 1 [Homo sapiens] 42 0.004
gi|58530842 desmoplakin isoform II [Homo sapiens] 41 0.005
gi|58530840 desmoplakin isoform I [Homo sapiens] 41 0.005
gi|33286444 mastermind-like 2 [Homo sapiens] 41 0.005
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 41 0.005
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 41 0.005
gi|154354979 myosin X [Homo sapiens] 41 0.005
gi|221219020 NYD-SP11 protein [Homo sapiens] 41 0.007
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 41 0.007
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 41 0.007
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 41 0.007
gi|23943882 serine/threonine kinase 33 [Homo sapiens] 41 0.007
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 41 0.007
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 41 0.007
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 41 0.007
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 41 0.007
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 41 0.007
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 41 0.007
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 41 0.007
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 41 0.007
>gi|59814247 budding uninhibited by benzimidazoles 1 beta [Homo
sapiens]
Length = 1050
Score = 2111 bits (5469), Expect = 0.0
Identities = 1050/1050 (100%), Positives = 1050/1050 (100%)
Query: 1 MAAVKKEGGALSEAMSLEGDEWELSKENVQPLRQGRIMSTLQGALAQESACNNTLQQQKR 60
MAAVKKEGGALSEAMSLEGDEWELSKENVQPLRQGRIMSTLQGALAQESACNNTLQQQKR
Sbjct: 1 MAAVKKEGGALSEAMSLEGDEWELSKENVQPLRQGRIMSTLQGALAQESACNNTLQQQKR 60
Query: 61 AFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLERAVEALQGEKRYYSDPR 120
AFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLERAVEALQGEKRYYSDPR
Sbjct: 61 AFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLERAVEALQGEKRYYSDPR 120
Query: 121 FLNLWLKLGRLCNEPLDMYSYLHNQGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQ 180
FLNLWLKLGRLCNEPLDMYSYLHNQGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQ
Sbjct: 121 FLNLWLKLGRLCNEPLDMYSYLHNQGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQ 180
Query: 181 QKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGKKTARA 240
QKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGKKTARA
Sbjct: 181 QKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGKKTARA 240
Query: 241 PIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPM 300
PIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPM
Sbjct: 241 PIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPM 300
Query: 301 PRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQQPVMTPCKIEP 360
PRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQQPVMTPCKIEP
Sbjct: 301 PRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQQPVMTPCKIEP 360
Query: 361 SINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVF 420
SINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVF
Sbjct: 361 SINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVF 420
Query: 421 RKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKL 480
RKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKL
Sbjct: 421 RKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKL 480
Query: 481 QIASESQKIPGMTLSSSVCQVNCCARETSLAENIWQEQPHSKGPSVPFSIFDEFLLSEKK 540
QIASESQKIPGMTLSSSVCQVNCCARETSLAENIWQEQPHSKGPSVPFSIFDEFLLSEKK
Sbjct: 481 QIASESQKIPGMTLSSSVCQVNCCARETSLAENIWQEQPHSKGPSVPFSIFDEFLLSEKK 540
Query: 541 NKSPPADPPRVLAQRRPLAVLKTSESITSNEDVSPDVCDEFTGIEPLSEDAIITGFRNVT 600
NKSPPADPPRVLAQRRPLAVLKTSESITSNEDVSPDVCDEFTGIEPLSEDAIITGFRNVT
Sbjct: 541 NKSPPADPPRVLAQRRPLAVLKTSESITSNEDVSPDVCDEFTGIEPLSEDAIITGFRNVT 600
Query: 601 ICPNPEDTCDFARAARFVSTPFHEIMSLKDLPSDPERLLPEEDLDVKTSEDQQTACGTIY 660
ICPNPEDTCDFARAARFVSTPFHEIMSLKDLPSDPERLLPEEDLDVKTSEDQQTACGTIY
Sbjct: 601 ICPNPEDTCDFARAARFVSTPFHEIMSLKDLPSDPERLLPEEDLDVKTSEDQQTACGTIY 660
Query: 661 SQTLSIKKLSPIIEDSREATHSSGFSGSSASVASTSSIKCLQIPEKLELTNETSENPTQS 720
SQTLSIKKLSPIIEDSREATHSSGFSGSSASVASTSSIKCLQIPEKLELTNETSENPTQS
Sbjct: 661 SQTLSIKKLSPIIEDSREATHSSGFSGSSASVASTSSIKCLQIPEKLELTNETSENPTQS 720
Query: 721 PWCSQYRRQLLKSLPELSASAELCIEDRPMPKLEIEKEIELGNEDYCIKREYLICEDYKL 780
PWCSQYRRQLLKSLPELSASAELCIEDRPMPKLEIEKEIELGNEDYCIKREYLICEDYKL
Sbjct: 721 PWCSQYRRQLLKSLPELSASAELCIEDRPMPKLEIEKEIELGNEDYCIKREYLICEDYKL 780
Query: 781 FWVAPRNSAELTVIKVSSQPVPWDFYINLKLKERLNEDFDHFCSCYQYQDGCIVWHQYIN 840
FWVAPRNSAELTVIKVSSQPVPWDFYINLKLKERLNEDFDHFCSCYQYQDGCIVWHQYIN
Sbjct: 781 FWVAPRNSAELTVIKVSSQPVPWDFYINLKLKERLNEDFDHFCSCYQYQDGCIVWHQYIN 840
Query: 841 CFTLQDLLQHSEYITHEITVLIIYNLLTIVEMLHKAEIVHGDLSPRCLILRNRIHDPYDC 900
CFTLQDLLQHSEYITHEITVLIIYNLLTIVEMLHKAEIVHGDLSPRCLILRNRIHDPYDC
Sbjct: 841 CFTLQDLLQHSEYITHEITVLIIYNLLTIVEMLHKAEIVHGDLSPRCLILRNRIHDPYDC 900
Query: 901 NKNNQALKIVDFSYSVDLRVQLDVFTLSGFRTVQILEGQKILANCSSPYQVDLFGIADLA 960
NKNNQALKIVDFSYSVDLRVQLDVFTLSGFRTVQILEGQKILANCSSPYQVDLFGIADLA
Sbjct: 901 NKNNQALKIVDFSYSVDLRVQLDVFTLSGFRTVQILEGQKILANCSSPYQVDLFGIADLA 960
Query: 961 HLLLFKEHLQVFWDGSFWKLSQNISELKDGELWNKFFVRILNANDEATVSVLGELAAEMN 1020
HLLLFKEHLQVFWDGSFWKLSQNISELKDGELWNKFFVRILNANDEATVSVLGELAAEMN
Sbjct: 961 HLLLFKEHLQVFWDGSFWKLSQNISELKDGELWNKFFVRILNANDEATVSVLGELAAEMN 1020
Query: 1021 GVFDTTFQSHLNKALWKVGKLTSPGALLFQ 1050
GVFDTTFQSHLNKALWKVGKLTSPGALLFQ
Sbjct: 1021 GVFDTTFQSHLNKALWKVGKLTSPGALLFQ 1050
>gi|4757878 budding uninhibited by benzimidazoles 1 [Homo sapiens]
Length = 1085
Score = 119 bits (298), Expect = 1e-26
Identities = 59/161 (36%), Positives = 93/161 (57%), Gaps = 2/161 (1%)
Query: 53 NTLQQQKRAFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLERAVEALQGE 112
+T + + E ++ Y GNDPL W+RYI W E+N+P+ + + TLLE ++ +
Sbjct: 2 DTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPEN--KEYLITLLEHLMKEFLDK 59
Query: 113 KRYYSDPRFLNLWLKLGRLCNEPLDMYSYLHNQGIGVSLAQFYISWAEEYEARENFRKAD 172
K+Y++DPRF++ LK ++ + +L+N GIG + YI+WA EA+ + A
Sbjct: 60 KKYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHAS 119
Query: 173 AIFQEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEE 213
A+ Q GIQ +AEP E LQ Q+R FQ R++ L A + E
Sbjct: 120 AVLQRGIQNQAEPREFLQQQYRLFQTRLTETHLPAQARTSE 160
Score = 112 bits (280), Expect = 2e-24
Identities = 123/514 (23%), Positives = 223/514 (43%), Gaps = 74/514 (14%)
Query: 579 DEFTGIEPLSEDAIITGFR-NVTICPNPEDTCDFARAARFVSTPFHEIMSLKDLPSDPER 637
+E E +D+ + G R N T+ P+P+ DF AA+ STPFH+ LP +
Sbjct: 567 EEVPHAEEFLDDSTVWGIRCNKTLAPSPKSPGDFTSAAQLASTPFHK------LPVESVH 620
Query: 638 LLPEEDLDVKTSEDQQTACGTIYSQTLSIK--KLSPIIEDS-REATHSSGFSGSSASVAS 694
+L +++ V Q T + + + K SPI E S ++A S +S S ++
Sbjct: 621 ILEDKENVVAKQCTQATLDSCEENMVVPSRDGKFSPIQEKSPKQALSSHMYSASLLRLSQ 680
Query: 695 TSSIKCLQIPEKL-----ELTNETS---ENPTQS-------------------------- 720
++ L +L LT+ + E+P +
Sbjct: 681 PAAGGVLTCEAELGVEACRLTDTDAAIAEDPPDAIAGLQAEWMQMSSLGTVDAPNFIVGN 740
Query: 721 PWCSQYRRQLLKSLPELSASAELCIEDR-PMPKLEIEKEIELGNEDYCIKR---EYLICE 776
PW + +LL L + +S E + +P ++ + E +LG++ + E +
Sbjct: 741 PWDDKLIFKLLSGLSKPVSSYPNTFEWQCKLPAIKPKTEFQLGSKLVYVHHLLGEGAFAQ 800
Query: 777 DYKLFW--VAPRNSAELTVIKVSSQPVPWDFYINLKLKERLNEDFDH----FCSCYQYQD 830
Y+ + + + V+KV PW+FYI +L ERL H F S + +Q+
Sbjct: 801 VYEATQGDLNDAKNKQKFVLKVQKPANPWEFYIGTQLMERLKPSMQHMFMKFYSAHLFQN 860
Query: 831 GCIVWHQYINCFTLQDLLQ-----HSEYITHEITVLIIYNLLTIVEMLHKAEIVHGDLSP 885
G ++ + + TL + + + + + + +L ++E +H EI+HGD+ P
Sbjct: 861 GSVLVGELYSYGTLLNAINLYKNTPEKVMPQGLVISFAMRMLYMIEQVHDCEIIHGDIKP 920
Query: 886 RCLILRNRIHDPYDCNKNNQALKIVDFSYSVDLRV--QLDVFTL----SGFRTVQILEGQ 939
IL N + D + + L ++D S+D+++ + +FT SGF+ V++L
Sbjct: 921 DNFILGNGFLEQDDEDDLSAGLALIDLGQSIDMKLFPKGTIFTAKCETSGFQCVEML--- 977
Query: 940 KILANCSSPYQVDLFGIADLAHLLLFKEHLQVFWDGSFWKLSQNISELKDGELWNKFFVR 999
+N YQ+D FG+A + +LF +++V +G K L ++WN+FF
Sbjct: 978 ---SNKPWNYQIDYFGVAATVYCMLFGTYMKVKNEGGECKPEGLFRRLPHLDMWNEFFHV 1034
Query: 1000 ILNANDEATVSVLGELAAEMNGVFDTTFQSHLNK 1033
+LN D + L L ++ VF Q + NK
Sbjct: 1035 MLNIPDCHHLPSLDLLRQKLKKVFQ---QHYTNK 1065
Score = 51.6 bits (122), Expect = 4e-06
Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 8/98 (8%)
Query: 382 VQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAE 441
V S + + ++ +MYCKEK+ G EFSFEE+RA+ + ++ K ++ KR E
Sbjct: 221 VHSSLASKVDVEQVVMYCKEKLIRGESEFSFEELRAQKYNQRRKHEQWVNEDRHYMKRKE 280
Query: 442 --------MQKQIEEMEKKLKEIQTTQQERTGDQQEET 471
++++++E+ KKL ++ T E QE +
Sbjct: 281 ANAFEEQLLKQKMDELHKKLHQVVETSHEDLPASQERS 318
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 45.8 bits (107), Expect = 2e-04
Identities = 88/398 (22%), Positives = 153/398 (38%), Gaps = 41/398 (10%)
Query: 341 TPYVEETA-QQPVMTPCKIEPSINHI--LSTRKPGKEEGDPLQRVQSHQQASE-EKKEKM 396
TP V++T +Q + ++P+ + S RK KEE + +V ++ + E KEK+
Sbjct: 527 TPVVKQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKV 586
Query: 397 MYCKEKIYAGVGEFSFEE-----------IRAEVFRKK---LKEQREAELLTSAEKRAEM 442
M K+K + S E ++AEV K+ +K + E E + +
Sbjct: 587 MVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKP 646
Query: 443 QKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQKIPGMTLSSSVCQVN 502
+ + EE EK KE+ ++++T ++EE P KE K ++ E +K V +
Sbjct: 647 EDKKEEKEKPKKEV-AKKEDKTPIKKEEK-PKKEEVKKEVKKEIKKEEKKEPKKEV-KKE 703
Query: 503 CCARETSLAENIWQEQPHSKGPSVPFSIFDEFLLSEKKNKSP--PADPPRVLAQRRPLAV 560
+E +++ K P + KK+ +P A P L + P
Sbjct: 704 TPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVP--- 760
Query: 561 LKTSESITSNEDVSPDVCDEFTGIEPLSEDAIITGFRNVTICPNPEDTCDFARAARFVST 620
K ES+ + V+ E I+ + ++ + A A
Sbjct: 761 -KKEESV-KKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIG 818
Query: 621 PFHEIMSLKDLPSDPERL------LPEEDLDVKTSEDQQTACGTIYSQTLSIKKLSP--- 671
P E+ + + L S PE L L E++DV Q + +K+ P
Sbjct: 819 PAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQL---ELIEDEEKLKETEPVEA 875
Query: 672 -IIEDSREATHSSGFSGSSASVASTSSIKCLQIPEKLE 708
+I+ RE T S + +C Q PE+LE
Sbjct: 876 YVIQKEREVTKGPAESPDEGITTTEGEGECEQTPEELE 913
Score = 31.6 bits (70), Expect = 4.1
Identities = 59/343 (17%), Positives = 137/343 (39%), Gaps = 48/343 (13%)
Query: 160 EEYEARENFRKADAIFQEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFES 219
++ E +E +K A ++ K E + + ++ + + ++ EK+E ++ +
Sbjct: 648 DKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKE-----EKKEPKKEVKK 702
Query: 220 SVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENA 279
P + E+K + KK + ++ + I ++A
Sbjct: 703 ETPPKEVKKEVKKEEKKEVK-----------------------KEEKEPKKEIKKLPKDA 739
Query: 280 DEAST--AELSKP-TVQPWIAPPMPRAKENELQAG-PWNTGRSLEHRPRGNTASLIAVPA 335
++ST +E KP ++P + K++ + AG P G+ + G A +A
Sbjct: 740 KKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAV 799
Query: 336 VLPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEK 395
+ T V A + P K + ++S+ + ++ + L+ + + + +
Sbjct: 800 GTGATTAAVMAAAGIAAIGPAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLE 859
Query: 396 MMYCKEKIYAGVGEFSFEEIRAEVFRK-----KLKEQREAELLTSAEKRAEMQKQIEEME 450
++ +EK+ E + A V +K K + E +T+ E E ++ EE+E
Sbjct: 860 LIEDEEKLK------ETEPVEAYVIQKEREVTKGPAESPDEGITTTEGEGECEQTPEELE 913
Query: 451 ----KKLKEIQTTQQERTG-DQQEETMPTKETTKLQIASESQK 488
+ + +I+ + E G ++ ET +E + + A E ++
Sbjct: 914 PVEKQGVDDIEKFEDEGAGFEESSETGDYEEKAETEEAEEPEE 956
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 44.7 bits (104), Expect = 5e-04
Identities = 36/125 (28%), Positives = 67/125 (53%), Gaps = 10/125 (8%)
Query: 370 KPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQRE 429
K +EE QR++S QQ E++E+ +E++ E E+ R E K+ +E+R
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEER----REQLLKREEEKRLEQERREQRLKREQEERR 575
Query: 430 AELLTSAEKRAEM---QKQIEEMEKKLK--EIQTTQQERTGDQQ-EETMPTKETTKLQIA 483
+LL E+R + ++Q E +E++LK E++ +QE +Q+ + P +E + +
Sbjct: 576 DQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLK 635
Query: 484 SESQK 488
SE Q+
Sbjct: 636 SEEQE 640
Score = 38.5 bits (88), Expect = 0.034
Identities = 30/127 (23%), Positives = 61/127 (48%), Gaps = 4/127 (3%)
Query: 365 ILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKL 424
+L R+ G+EE QR + + +E++EK +E + E +E + R+
Sbjct: 215 LLELRRKGREEKQQ-QRRERQDRVFQEEEEKEWRKRETVLRKEEE-KLQEEEPQRQRELQ 272
Query: 425 KEQREAELLTSAEKRAEMQKQIEEMEKKLKE--IQTTQQERTGDQQEETMPTKETTKLQI 482
+E+ + L E R E Q++ ++ ++ +E ++ Q+E +QQEE +E + Q
Sbjct: 273 EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 483 ASESQKI 489
Q++
Sbjct: 333 ERREQQL 339
Score = 36.6 bits (83), Expect = 0.13
Identities = 30/118 (25%), Positives = 55/118 (46%), Gaps = 12/118 (10%)
Query: 383 QSHQQASEEKKEK----MMYCKEKIYAGVGEFS----FEEIRAEVFRKKLKEQREAELLT 434
++H+Q EE++ + +EK G S E R R + ++QRE L
Sbjct: 753 RAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLP 812
Query: 435 SAEKRAEMQKQIEEMEKKL----KEIQTTQQERTGDQQEETMPTKETTKLQIASESQK 488
E++ + ++Q E EK+L +E Q ++ER QEE +E + + + E ++
Sbjct: 813 EEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRR 870
Score = 36.2 bits (82), Expect = 0.17
Identities = 27/115 (23%), Positives = 59/115 (51%), Gaps = 7/115 (6%)
Query: 373 KEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAEL 432
+E+ L+R + ++ EE++++ +E+ E E + E R++ +E+RE +
Sbjct: 275 EEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE--RREQQERREQQ- 331
Query: 433 LTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQ 487
E+R E Q + E+ E++ ++++ Q+E +QQ +E + Q+ E Q
Sbjct: 332 ----EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ 382
Score = 36.2 bits (82), Expect = 0.17
Identities = 26/124 (20%), Positives = 65/124 (52%), Gaps = 4/124 (3%)
Query: 369 RKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAE--VFRKKLKE 426
++ +E D L + + ++ K+E+ ++++ E +E R E + R++ +E
Sbjct: 568 KREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEE 627
Query: 427 QREAELLTSAEKRAEMQKQI--EEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIAS 484
+R +LL S E+ Q+Q+ E+ E++ + ++ ++E +Q+ + +E + ++A
Sbjct: 628 ERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE 687
Query: 485 ESQK 488
E Q+
Sbjct: 688 EEQE 691
Score = 35.4 bits (80), Expect = 0.28
Identities = 25/101 (24%), Positives = 52/101 (51%), Gaps = 12/101 (11%)
Query: 369 RKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQR 428
R+ +EE QR++ QQ +++E+ +E E + R++ +E+R
Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQE-----------ERREQQERREQQEERR 335
Query: 429 EAELLTSAEKRAEMQ-KQIEEMEKKLKEIQTTQQERTGDQQ 468
E +L E+R E Q ++ +E E++ ++++ Q+E +QQ
Sbjct: 336 EQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQ 376
Score = 35.0 bits (79), Expect = 0.37
Identities = 22/97 (22%), Positives = 52/97 (53%), Gaps = 15/97 (15%)
Query: 374 EEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELL 433
E+ + ++ ++ EE++++++ +E+ EE R + R++ +E+RE L
Sbjct: 611 EQEERREQRLKREEPEEERRQQLLKSEEQ----------EERRQQQLRREQQERREQRL- 659
Query: 434 TSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEE 470
KR E ++++E+ K+ E + +QE ++QE+
Sbjct: 660 ----KREEEEERLEQRLKREHEEERREQELAEEEQEQ 692
Score = 34.3 bits (77), Expect = 0.63
Identities = 24/124 (19%), Positives = 64/124 (51%), Gaps = 7/124 (5%)
Query: 369 RKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQR 428
++ +E D L+R + ++ +E++++ + ++ EE R++ +E+R
Sbjct: 448 KREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEE----RREQQERR 503
Query: 429 EAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQ---EETMPTKETTKLQIASE 485
E +L E+R E + + +E E++L++ ++Q+ +Q+ E+ + +E +L+
Sbjct: 504 EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563
Query: 486 SQKI 489
Q++
Sbjct: 564 EQRL 567
Score = 34.3 bits (77), Expect = 0.63
Identities = 33/144 (22%), Positives = 65/144 (45%), Gaps = 6/144 (4%)
Query: 345 EETAQQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIY 404
EE QQ + EP + +EE + Q + Q EE++++ E+ Y
Sbjct: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQ--EEEQLLREEREKRRRQELERQY 1140
Query: 405 AGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERT 464
E EE ++ R++ +++R EL + E+Q++ E++ ++ E + +QER
Sbjct: 1141 REEEEVQQEE--EQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE--EQEKRRQERE 1196
Query: 465 GDQQEETMPTKETTKLQIASESQK 488
+EE ++ K + E Q+
Sbjct: 1197 RQYREEEELQRQKRKQRYRDEDQR 1220
Score = 33.9 bits (76), Expect = 0.83
Identities = 25/112 (22%), Positives = 56/112 (50%), Gaps = 3/112 (2%)
Query: 377 DPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSA 436
D LQ+ + Q EE++++ + +E+ Y E EE ++ ++ + +R EL
Sbjct: 1024 DELQQ-EEEQLLREEREKRRLQERERQYREEEELQQEE--EQLLGEERETRRRQELERQY 1080
Query: 437 EKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQK 488
K E+Q++ E++ ++ E + Q+ ++EE + +E L+ E ++
Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRR 1132
Score = 33.5 bits (75), Expect = 1.1
Identities = 24/117 (20%), Positives = 58/117 (49%), Gaps = 1/117 (0%)
Query: 373 KEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKK-LKEQREAE 431
++E + LQ + +Q +++E+ + E+ E+ + + R++ L+ ++E E
Sbjct: 254 RKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE 313
Query: 432 LLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQK 488
E+R E Q++ E+ E++ ++ +QE +QQ +E + Q+ E ++
Sbjct: 314 RREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEE 370
Score = 33.5 bits (75), Expect = 1.1
Identities = 23/106 (21%), Positives = 53/106 (50%), Gaps = 2/106 (1%)
Query: 383 QSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEM 442
+ Q EE +++ +EK Y E EE ++ R++ +++R E K+ E+
Sbjct: 969 KEEQLLGEEPEKRRRQEREKKYREEEELQQEE--EQLLREEREKRRRQEWERQYRKKDEL 1026
Query: 443 QKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQK 488
Q++ E++ ++ +E + Q+ ++EE + +E L E+++
Sbjct: 1027 QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRR 1072
Score = 33.5 bits (75), Expect = 1.1
Identities = 28/122 (22%), Positives = 57/122 (46%), Gaps = 9/122 (7%)
Query: 373 KEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSF----EEIRAEVFRKKLKEQR 428
+EE LQ + Q +E+ K ++++ E F +++R + +K +E+
Sbjct: 1670 REEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEE 1729
Query: 429 EAELLTSAE--KRAEMQKQI---EEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIA 483
+ T E +R E ++I E++ + +E Q +QER +EE +E + Q+
Sbjct: 1730 QLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLR 1789
Query: 484 SE 485
S+
Sbjct: 1790 SQ 1791
Score = 32.7 bits (73), Expect = 1.8
Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 5/98 (5%)
Query: 373 KEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAEL 432
+EE + +R + +Q EE E++ +E++ E + R +RK K Q++ E
Sbjct: 915 REEREKRRRQEQERQYREE--EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ 972
Query: 433 LTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEE 470
L E +++ +E EKK +E + QQE +EE
Sbjct: 973 LLGEEPE---KRRRQEREKKYREEEELQQEEEQLLREE 1007
Score = 32.3 bits (72), Expect = 2.4
Identities = 29/119 (24%), Positives = 64/119 (53%), Gaps = 13/119 (10%)
Query: 374 EEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELL 433
EE + LQR + QQ EE+ + + +E+ S E+ R + +R +L+E+R+
Sbjct: 835 EEEEQLQRRERAQQLQEEE-DGLQEDQER------RRSQEQRRDQKWRWQLEEERKRRRH 887
Query: 434 TSAEKRA---EMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQKI 489
T K A +++K+ + ++++ +E+Q ++E+ Q++E +E Q+ E +++
Sbjct: 888 TLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEE---QLQQEEEQL 943
Score = 32.3 bits (72), Expect = 2.4
Identities = 29/123 (23%), Positives = 57/123 (46%), Gaps = 12/123 (9%)
Query: 374 EEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKK----LKEQRE 429
EE L+R + QQ ++ K ++ + G + + R FR++ +++RE
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERE 1706
Query: 430 AELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQ---QEETMPTKETTKLQIASES 486
+ L + E Q + +E+E+K +E + +QE +Q QE E +L+ E
Sbjct: 1707 RKFL-----QEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREE 1761
Query: 487 QKI 489
Q++
Sbjct: 1762 QQL 1764
Score = 32.0 bits (71), Expect = 3.1
Identities = 20/98 (20%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
Query: 373 KEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAEL 432
+EE + +R + +Q ++KK + +E++ E + R + +R++ + Q+E E
Sbjct: 945 REEREKRRRQERERQYRKDKK--LQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQ 1002
Query: 433 LTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEE 470
L E+ +++ E +K E+Q +++ +++E+
Sbjct: 1003 LLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREK 1040
Score = 31.6 bits (70), Expect = 4.1
Identities = 18/98 (18%), Positives = 50/98 (51%), Gaps = 11/98 (11%)
Query: 373 KEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAEL 432
+E+ + + Q ++ EE++E+ + ++++ R + R++ + +RE +L
Sbjct: 353 REQEEERREQQLRREQEEERREQQLRREQQLR-----------REQQLRREQQLRREQQL 401
Query: 433 LTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEE 470
+ R E Q + E+ ++ ++++ Q+E +Q+ E
Sbjct: 402 RREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHE 439
Score = 31.6 bits (70), Expect = 4.1
Identities = 20/98 (20%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
Query: 373 KEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAEL 432
+EE + +R + +Q KK+++ +E++ E + R +R++ + Q+E E
Sbjct: 1005 REEREKRRRQEWERQY--RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQ 1062
Query: 433 LTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEE 470
L E+ ++++E +K +E+Q +++ ++ E+
Sbjct: 1063 LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEK 1100
Score = 31.2 bits (69), Expect = 5.4
Identities = 26/123 (21%), Positives = 59/123 (47%), Gaps = 3/123 (2%)
Query: 366 LSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLK 425
L R+ E + LQ+ + Q EE++ + E+ Y E EE ++ R++ +
Sbjct: 1043 LQERERQYREEEELQQ-EEEQLLGEERETRRRQELERQYRKEEELQQEE--EQLLREEPE 1099
Query: 426 EQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASE 485
++R E + E+Q++ E++ ++ +E + Q+ ++EE + +E L+ E
Sbjct: 1100 KRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPE 1159
Query: 486 SQK 488
++
Sbjct: 1160 KRR 1162
Score = 30.8 bits (68), Expect = 7.0
Identities = 18/91 (19%), Positives = 48/91 (52%), Gaps = 2/91 (2%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
++ + +Q +E++E+ + +++ G + E+++ E ++L+++R+ + +
Sbjct: 1795 RKFREEEQLRQEREEQQLRPQQR--DGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFA 1852
Query: 440 AEMQKQIEEMEKKLKEIQTTQQERTGDQQEE 470
+ + + EE E +E Q +QER +EE
Sbjct: 1853 TQEKSRREEQELWQEEEQKRRQERERKLREE 1883
Score = 30.4 bits (67), Expect = 9.1
Identities = 24/112 (21%), Positives = 50/112 (44%), Gaps = 16/112 (14%)
Query: 373 KEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAE-----VFRKKLKEQ 427
+EE D LQ Q +++ E+++++ + EE R + L+EQ
Sbjct: 850 QEEEDGLQEDQERRRSQEQRRDQKW-----------RWQLEEERKRRRHTLYAKPALQEQ 898
Query: 428 REAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTK 479
E E+ E+Q++ E ++ ++ + ++E Q+EE + +E K
Sbjct: 899 LRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREK 950
>gi|4758128 doublecortin-like kinase 1 [Homo sapiens]
Length = 729
Score = 44.3 bits (103), Expect = 6e-04
Identities = 67/298 (22%), Positives = 119/298 (39%), Gaps = 53/298 (17%)
Query: 670 SPIIEDSREATHSSGFSGSSASVASTSSIKCLQIPEKLELTNETSENPTQSPWCSQYRRQ 729
SP S SS GSS S+AST C + E E SE Q P R +
Sbjct: 334 SPTSPGSLRKQRSSQHGGSSTSLASTKV--CSSMDENDGPGEEVSEEGFQIPATITERYK 391
Query: 730 LLKSLPELS-ASAELCIEDRPMPK--LEIEKEIELGNEDYCIKREYLICEDYKLFWVAPR 786
+ +++ + + A + C+E + L+I K+ + +++ I+ E I K
Sbjct: 392 VGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVK------- 444
Query: 787 NSAELTVIKVSSQPVPWDFYINLKLKERLNEDFDHFCSCYQYQDGCIVWHQYINCFTLQD 846
V+ + VP + Y+ ++L + + FD S +Y
Sbjct: 445 --HPNIVLLIEEMDVPTELYLVMELVKG-GDLFDAITSTNKY------------------ 483
Query: 847 LLQHSEYITHEITVLIIYNLLTIVEMLHKAEIVHGDLSPRCLILRNRIHDPYDCNKNNQA 906
T ++YNL + ++ LH IVH D+ P L++ Y+ +++
Sbjct: 484 --------TERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLV-------YEHQDGSKS 528
Query: 907 LKIVDFSYSVDLRVQLDVFTLSGFRTVQILEGQKILANCSSPYQVDLFGIADLAHLLL 964
LK+ DF + V ++T+ G T E I+A +VD++ + ++LL
Sbjct: 529 LKLGDFGLAT--IVDGPLYTVCGTPTYVAPE---IIAETGYGLKVDIWAAGVITYILL 581
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 43.5 bits (101), Expect = 0.001
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 2/111 (1%)
Query: 386 QQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQ 445
Q+A E +KE+++ E+I E+I+ K + + E L + M KQ
Sbjct: 614 QEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQ 673
Query: 446 IEEMEKKLKEIQ--TTQQERTGDQQEETMPTKETTKLQIASESQKIPGMTL 494
+E++EK+ KE+Q QE+ D E +E ++ A E Q+I M L
Sbjct: 674 VEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDL 724
Score = 35.8 bits (81), Expect = 0.22
Identities = 30/106 (28%), Positives = 54/106 (50%), Gaps = 5/106 (4%)
Query: 383 QSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEM 442
+ H + E K+++ + Y E E+ RAE + LKE+ E E A KR E
Sbjct: 786 ERHNRLEERKRQRKEERRITYYREKEEE--EQRRAE--EQMLKEREERERAERA-KREEE 840
Query: 443 QKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQK 488
++ +E KKL+E++ +++R + +E +E +L +S S+K
Sbjct: 841 LREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRK 886
Score = 31.2 bits (69), Expect = 5.4
Identities = 56/248 (22%), Positives = 103/248 (41%), Gaps = 42/248 (16%)
Query: 252 PSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPT-VQPWI------APPMPRAK 304
P + LQ PQ +QNN+ + + + + + E S+ T + P++ + A+
Sbjct: 418 PEKEPELQQYVPQ-LQNNTILRLLQQVSQIYQSIEFSRLTSLVPFVDAFQLERAIVDAAR 476
Query: 305 ENELQAGPWNTGRSLEHRPRGNTASLIAVPA-----VLPSFTPYVEETAQQPVMT----- 354
+LQ +T R+L N A+ P +PS + TA V+
Sbjct: 477 HCDLQVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEV 536
Query: 355 --PCKI--EPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEF 410
P I E H L+ K QR+ + +Q EE+KE++
Sbjct: 537 IKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERL-------------- 582
Query: 411 SFEEIRAEVFRKKLKEQREAEL---LTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQ 467
E + + +++L EQREAEL + E+R + + E E+ L+E + +++ ++
Sbjct: 583 --ESLNIQREKEEL-EQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRER 639
Query: 468 QEETMPTK 475
E+ T+
Sbjct: 640 LEQIKKTE 647
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 43.5 bits (101), Expect = 0.001
Identities = 35/137 (25%), Positives = 68/137 (49%), Gaps = 8/137 (5%)
Query: 357 KIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEK---KEKMMYCKEKIYAGVGEFSFE 413
KI+ I + +E+ + ++R + EEK +E+MM+ KE+ + E E
Sbjct: 296 KIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 355
Query: 414 EIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQ--TTQQERTGDQQEET 471
+ E R++ ++++E E + EKR E + ++ E+K++E + +QE +QEE
Sbjct: 356 Q---EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEK 412
Query: 472 MPTKETTKLQIASESQK 488
M +E + E Q+
Sbjct: 413 MGEQEEKMWEQEEEMQE 429
Score = 43.1 bits (100), Expect = 0.001
Identities = 29/112 (25%), Positives = 62/112 (55%), Gaps = 6/112 (5%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
++++ ++ +E++EKM +EK++ E +E + +K++EQ E ++ EK
Sbjct: 397 EKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ-EKKIREQEEKI 455
Query: 440 AEMQKQIEEMEKKL--KEIQTTQQERTGDQQEETMPTKETTKLQIASESQKI 489
E ++ ++E E+K+ +E + +QE +QEE M +E +I + +KI
Sbjct: 456 REQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEE---KIREQEKKI 504
Score = 40.8 bits (94), Expect = 0.007
Identities = 29/119 (24%), Positives = 64/119 (53%), Gaps = 9/119 (7%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAE---VFRKKLKEQREAELLTSA 436
++++ ++ EK+EK+ +EK++ EE R E + ++ ++++EA++
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389
Query: 437 EKRAEMQKQIEEMEKKLKEIQTT---QQERTGDQQEETMPTKETTKLQ---IASESQKI 489
EK E +++I E E+ ++E + Q+E+ +Q+EE +E + Q I + +KI
Sbjct: 390 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448
Score = 39.3 bits (90), Expect = 0.020
Identities = 28/111 (25%), Positives = 56/111 (50%), Gaps = 11/111 (9%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
++++ ++ E++E M +EK+ G+ +E + + +K++ Q E K
Sbjct: 446 KKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEE--------KI 497
Query: 440 AEMQKQIEEMEKKLKEIQTTQQERTGD--QQEETMPTKETTKLQIASESQK 488
E +K+I E E+K++E + QE+ +QEE M +E K+Q E +
Sbjct: 498 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE-EKMQEQEEKMR 547
Score = 38.1 bits (87), Expect = 0.044
Identities = 28/116 (24%), Positives = 56/116 (48%), Gaps = 15/116 (12%)
Query: 376 GDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQ-------- 427
G+ +++ ++ +E++EKM +EKI + +E + + ++EQ
Sbjct: 414 GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQE 473
Query: 428 -----REAELLTSAEKRAEMQKQIEEMEKKLKEIQ--TTQQERTGDQQEETMPTKE 476
+EA++ EK +++I E EKK++E + +QE +QEE M +E
Sbjct: 474 GKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 529
Score = 35.8 bits (81), Expect = 0.22
Identities = 25/110 (22%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
+ +Q ++ E++EKM +E++ + +E + KK++EQ E ++ E
Sbjct: 404 EMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEE-KIREQEEMM 462
Query: 440 AEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQKI 489
E ++++ E E K+ E + QE+ + + +E K +I + +KI
Sbjct: 463 QEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEK-KIREQEEKI 511
Score = 35.4 bits (80), Expect = 0.28
Identities = 29/125 (23%), Positives = 59/125 (47%), Gaps = 17/125 (13%)
Query: 376 GDPLQRVQSHQQA-----------SEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKL 424
G LQ V + QA +++++EKM +EKI + +E + +K+
Sbjct: 259 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKM 318
Query: 425 KEQ------REAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETT 478
+ Q +E ++ E E +++I E+E+K+ E + +++ Q+EE + +E
Sbjct: 319 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 378
Query: 479 KLQIA 483
+ Q A
Sbjct: 379 QEQEA 383
Score = 33.5 bits (75), Expect = 1.1
Identities = 24/91 (26%), Positives = 47/91 (51%), Gaps = 6/91 (6%)
Query: 386 QQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQ 445
++ E++EK+ +E + + +E + ++++EQ E ++ EK E +K+
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE-KMRRQEEKIREQEKK 447
Query: 446 IEEMEKKLKEIQTTQQERTGDQQEETMPTKE 476
I E E+K++E QE +QEE M +E
Sbjct: 448 IREQEEKIRE-----QEEMMQEQEEKMGEQE 473
Score = 33.5 bits (75), Expect = 1.1
Identities = 29/129 (22%), Positives = 64/129 (49%), Gaps = 10/129 (7%)
Query: 369 RKPGKEEGDPLQRVQSHQQASEEKKEKM-----MYCKE--KIYAGVGEFSFEEIRAEVFR 421
R+ K+ + ++++ ++ +E++EKM C++ K+ + +E +
Sbjct: 442 REQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQE 501
Query: 422 KKLKEQREAELLTSAEKRAEMQKQIEEMEKKL--KEIQTTQQERTGDQQEETMPTKETTK 479
KK++EQ E ++ E E ++++ E E+K+ +E + +QE +QEE M +E
Sbjct: 502 KKIREQEE-KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRL 560
Query: 480 LQIASESQK 488
Q + Q+
Sbjct: 561 RQQEEKMQE 569
Score = 31.2 bits (69), Expect = 5.4
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 7/92 (7%)
Query: 390 EEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEM 449
EE KEK +EK+ E S EI+ V K K +R LL + +AE +E+
Sbjct: 205 EELKEKNAKLQEKLQLVESEKS--EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 262
Query: 450 EKKLKEIQTTQQE-----RTGDQQEETMPTKE 476
+ ++Q +E R QQEE M +E
Sbjct: 263 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQE 294
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 43.5 bits (101), Expect = 0.001
Identities = 40/170 (23%), Positives = 72/170 (42%), Gaps = 7/170 (4%)
Query: 303 AKENELQAGPWNTGRSLEH--RPRGNTASLIAVPAVLPSFTPYVEETAQQPVMTPCKIEP 360
AKE+ AGP + +S + + A P+ PS TP + Q P TP +
Sbjct: 514 AKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPT--DA 571
Query: 361 SINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVF 420
++ P P+ ++A+ EK +E+ E ++AE
Sbjct: 572 AVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQE---RRLQAERD 628
Query: 421 RKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEE 470
++ +EQ E AE+ AE +++ E+ ++ + + +QER Q+EE
Sbjct: 629 KRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEE 678
Score = 35.4 bits (80), Expect = 0.28
Identities = 22/90 (24%), Positives = 47/90 (52%), Gaps = 10/90 (11%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
Q + QA +E++E++ KE+ A R E R++L +RE ++R
Sbjct: 656 QEAREKAQAEQEEQERLQKQKEEAEA--------RSREEAERQRL--EREKHFQQQEQER 705
Query: 440 AEMQKQIEEMEKKLKEIQTTQQERTGDQQE 469
E +K++EE+ K+ ++ + ++ ++ D +E
Sbjct: 706 QERRKRLEEIMKRTRKSEVSETKQKQDSKE 735
Score = 33.5 bits (75), Expect = 1.1
Identities = 62/297 (20%), Positives = 102/297 (34%), Gaps = 83/297 (27%)
Query: 166 ENFRKADAIFQEGIQQKAEPLE--RLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQ 223
E KA A+ ++ +Q++ LE RL+++ R+ ++ L KE E + SV
Sbjct: 162 EKEEKAKALREKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSV-- 219
Query: 224 RSTLAELKSKGKKTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITV----FDENA 279
+ T AE++ + A A L + P + SR +V ++
Sbjct: 220 KKTWAEIRQQRWSWAGA-----------------LHHSSPGHKTSGSRCSVSAVNLPKHV 262
Query: 280 DEASTAELSKPTVQPWIAPPMPRAKENELQAGPWNT----------------GRSLEHRP 323
D LSK + W +P ++ LQ W + RS P
Sbjct: 263 DSIINKRLSKSSATLWNSP----SRNRSLQLSAWESSIVDRLMTPTLSFLARSRSAVTLP 318
Query: 324 RGNT------------------ASLIAVP---AVLPS-FTPYVEETAQQPVMTPCKIEPS 361
R ASL P PS P +A +TPC + S
Sbjct: 319 RNGRDQGRGCDPGRGPTWGRAGASLARGPQPDRTHPSAAVPVCPRSASASPLTPCSVTRS 378
Query: 362 INHIL------STRKPG----------KEEGDPLQRVQSHQQASEEKKEKMMYCKEK 402
++ RKP + E P+Q+ + + E +KEK +E+
Sbjct: 379 VHRCAPAGERGERRKPNAGGSPAPVRRRPEASPVQKKEKKDKERENEKEKSALARER 435
Score = 30.4 bits (67), Expect = 9.1
Identities = 46/213 (21%), Positives = 82/213 (38%), Gaps = 30/213 (14%)
Query: 296 IAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLP-SFTPYVEETAQQPVMT 354
+ P P + A P S E + RG T PA+ P P + P
Sbjct: 66 LEPESPSGQVGPRPAPPQEESPSSEAKSRGPTP-----PAMGPRDARPPRRSSQPSPTAV 120
Query: 355 PCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEE 414
P P T++ K+ G+ H+ A E ++E+ Y K + + E
Sbjct: 121 PASDSPP------TKQEVKKAGE------RHKLAKERREERAKYLAAKKAVWLEK----E 164
Query: 415 IRAEVFRKKLKEQR----EAELLTSAEKRAEM-QKQIEEMEKKLKEIQTTQQERTGDQQE 469
+A+ R+K ++R E + L + ++RA + ++Q +++EK + + Q
Sbjct: 165 EKAKALREKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWA 224
Query: 470 ETMPTKETTKLQIASESQKIPGMTLSSSVCQVN 502
E + + + S PG S S C V+
Sbjct: 225 EIRQQRWSWAGALHHSS---PGHKTSGSRCSVS 254
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 42.4 bits (98), Expect = 0.002
Identities = 36/142 (25%), Positives = 68/142 (47%), Gaps = 21/142 (14%)
Query: 366 LSTRKPGKEEGDPLQRVQSHQQASEEK----KEKMMYCKEKIYAGVGEFSFEEIRA---- 417
L +K +E+ + +Q + EEK +EKM +E+++ + +E +
Sbjct: 299 LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 358
Query: 418 -------EVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTT--QQERTGDQQ 468
E R+K + RE E + E++ + +++I E EKK++E + T +QE +Q
Sbjct: 359 ERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 418
Query: 469 EETMPTKETTKLQIASESQKIP 490
EE M +E + Q Q++P
Sbjct: 419 EENMWEQEEKEWQ----QQRLP 436
Score = 38.9 bits (89), Expect = 0.026
Identities = 29/103 (28%), Positives = 51/103 (49%), Gaps = 4/103 (3%)
Query: 386 QQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQ 445
QQ + ++EK +EK E EE R KK++E+ E + EK E +++
Sbjct: 531 QQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM-MREQEEKMQEQEEK 589
Query: 446 IEEMEKKL---KEIQTTQQERTGDQQEETMPTKETTKLQIASE 485
+ E E+K+ +E Q+E+ +Q+E+ +E K+Q E
Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEE 632
Score = 38.5 bits (88), Expect = 0.034
Identities = 28/126 (22%), Positives = 67/126 (53%), Gaps = 6/126 (4%)
Query: 369 RKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQR 428
R+ K+ + + ++ ++ +E++EKM +EK++ + +E + +K+ EQ
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 622
Query: 429 EAELLTSAEKRA-EMQKQIEEMEKKL--KEIQTTQQERTGDQQEETMPTKETTKLQIASE 485
E + + E+ E +++++E E+K+ +E + +QE +QEE M +E ++ +
Sbjct: 623 EEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE---KMREQ 679
Query: 486 SQKIPG 491
+K+ G
Sbjct: 680 EEKMQG 685
Score = 37.4 bits (85), Expect = 0.075
Identities = 25/99 (25%), Positives = 52/99 (52%), Gaps = 4/99 (4%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
+ ++ ++ +++EKM +E++ G+ +E + K+L+EQ + L EK
Sbjct: 241 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKE--LREQEKE 298
Query: 440 AEMQKQIEEMEKKLKEIQTT--QQERTGDQQEETMPTKE 476
QK++ E E++++E + +QE +QEE M +E
Sbjct: 299 LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE 337
Score = 37.4 bits (85), Expect = 0.075
Identities = 22/103 (21%), Positives = 57/103 (55%), Gaps = 5/103 (4%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLK-EQREAELLTSAEK 438
+++ ++ +E++EKM +EK++ E +E ++ ++ K +++E ++ EK
Sbjct: 595 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
Query: 439 RAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQ 481
E ++++ E E+K++ Q+E+ +Q+E+ +E + Q
Sbjct: 655 MREQEEKMREQEEKMQG----QEEKMREQEEKMQGQEEKMREQ 693
Score = 36.2 bits (82), Expect = 0.17
Identities = 21/113 (18%), Positives = 57/113 (50%), Gaps = 4/113 (3%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQR----EAELLTS 435
++++ + E++EKM ++K++ ++ R ++++EQ+ + E +
Sbjct: 479 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE 538
Query: 436 AEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQK 488
+K E +K+ + E+K++E + ++ ++EE M ++ K+Q E +
Sbjct: 539 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMR 591
Score = 35.8 bits (81), Expect = 0.22
Identities = 26/99 (26%), Positives = 54/99 (54%), Gaps = 4/99 (4%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
+R++ + E++EKM ++++ E +E +KKL+EQ E ++ EK
Sbjct: 262 ERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE-QKKLREQEE-QMQEQEEKM 319
Query: 440 AEMQKQIEEMEKKL--KEIQTTQQERTGDQQEETMPTKE 476
E ++++ E E+K+ +E + +QE+ +QE+ M +E
Sbjct: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 358
Score = 35.0 bits (79), Expect = 0.37
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 8/102 (7%)
Query: 369 RKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQR 428
R+ ++ D +R+ + EK+E+M +EK++ + EE R KK++E+
Sbjct: 348 REQEQKMRDQEERMWEQDERLREKEERMRE-QEKMWEQEEKMQEEE-RIREREKKMREEE 405
Query: 429 EAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEE 470
E T E+ +MQKQ E M + +E + QQ+R +Q+E+
Sbjct: 406 E----TMREQEEKMQKQEENMWE--QEEKEWQQQRLPEQKEK 441
Score = 35.0 bits (79), Expect = 0.37
Identities = 24/85 (28%), Positives = 47/85 (55%), Gaps = 7/85 (8%)
Query: 393 KEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREA-----ELLTSAEKRAEMQKQIE 447
+EK M+ +EK+ + +E + +K+ +Q E E L E+R QK++
Sbjct: 471 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMW 530
Query: 448 EMEKKLKEIQTTQQE--RTGDQQEE 470
+ E+K++E + TQ++ +T DQ+E+
Sbjct: 531 QQEEKMREEKKTQEQEKKTWDQEEK 555
Score = 34.7 bits (78), Expect = 0.48
Identities = 24/102 (23%), Positives = 54/102 (52%), Gaps = 12/102 (11%)
Query: 375 EGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLT 434
E + ++Q ++ E++EKM +EK++ +E + +K++EQ E ++
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWE-------QEEKMREQEEKMREQEE-KMQG 671
Query: 435 SAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKE 476
EK E +++++ E+K++E Q+E+ Q+E+ +E
Sbjct: 672 QEEKMREQEEKMQGQEEKMRE----QEEKMRGQEEKMWGQEE 709
Score = 33.5 bits (75), Expect = 1.1
Identities = 30/117 (25%), Positives = 58/117 (49%), Gaps = 6/117 (5%)
Query: 370 KPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFE-EIRAEVFRKKLKEQR 428
K +E+ Q ++ Q + ++E+ M +EK E E E + + +K++EQ
Sbjct: 535 KMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE 594
Query: 429 EAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASE 485
E ++ EK E ++++ E E+K+ E Q+E Q++E M ++ K+Q E
Sbjct: 595 E-KMWEQEEKMQEQEEKMWEQEEKMWE----QEEEDKMQEQEEMMWEQEEKMQEQEE 646
Score = 33.1 bits (74), Expect = 1.4
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 6/102 (5%)
Query: 379 LQRVQSH--QQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSA 436
L +VQ++ Q+ ++E++ ++KI + +E R K++EQ E +
Sbjct: 224 LPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEK--MRRQ 281
Query: 437 EKRA-EMQKQIEEMEKKLKE-IQTTQQERTGDQQEETMPTKE 476
EKR E +K++ E EK+L+E + +QE +QEE M +E
Sbjct: 282 EKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE 323
Score = 32.3 bits (72), Expect = 2.4
Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 17/111 (15%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
+R++ ++ E++E M +EK+ E +E+ E +++L EQ+E L EK
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQE-ENMWEQEEKEWQQQRLPEQKEK--LWEQEKM 448
Query: 440 AEMQKQIEEMEKKLK--------EIQTTQQERTGDQ------QEETMPTKE 476
E +++I E E+K++ E + +QE+ +Q QEE M +E
Sbjct: 449 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 499
Score = 32.3 bits (72), Expect = 2.4
Identities = 20/102 (19%), Positives = 50/102 (49%), Gaps = 12/102 (11%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQRE---------- 429
+++ ++ E++EKM +EK+ + +E + + +K++EQ E
Sbjct: 646 EKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMW 705
Query: 430 --AELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQE 469
E + E++ Q+++ E E+++++ + QER + +E
Sbjct: 706 GQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEE 747
Score = 31.6 bits (70), Expect = 4.1
Identities = 24/102 (23%), Positives = 47/102 (46%), Gaps = 13/102 (12%)
Query: 377 DPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSA 436
D +R+ + EK+E+M K+ + E R++ K Q + +
Sbjct: 504 DQEERMWEQDERLREKEERMREQKKMWQ-----------QEEKMREEKKTQEQEKKTWDQ 552
Query: 437 EKRAEMQKQIEEMEKKLKEIQ--TTQQERTGDQQEETMPTKE 476
E++ ++++ E EKK++E + +QE +QEE M +E
Sbjct: 553 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE 594
Score = 30.8 bits (68), Expect = 7.0
Identities = 26/113 (23%), Positives = 56/113 (49%), Gaps = 10/113 (8%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
+++Q ++ E++EKM +EK+ +E + + +K++EQ E ++ EK
Sbjct: 639 EKMQEQEEKMWEQEEKMREQEEKMRE-------QEEKMQGQEEKMREQEE-KMQGQEEKM 690
Query: 440 AEMQKQIEEMEKKL--KEIQTTQQERTGDQQEETMPTKETTKLQIASESQKIP 490
E ++++ E+K+ +E + QE QEE +E + Q +++P
Sbjct: 691 REQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLP 743
>gi|18390344 ATR interacting protein isoform 2 [Homo sapiens]
Length = 764
Score = 41.6 bits (96), Expect = 0.004
Identities = 29/110 (26%), Positives = 48/110 (43%), Gaps = 6/110 (5%)
Query: 386 QQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQ 445
Q +E KEKM +E++ GE L+EQR + L EK + +
Sbjct: 118 QAQYKELKEKMKVMEEEVLIKNGEIKILRDSLHQTESVLEEQRRSHFLLEQEKTQALSDK 177
Query: 446 IEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQKIPGMTLS 495
+E KKL+ +Q+ Q + + E TKLQ + + K+ ++S
Sbjct: 178 EKEFSKKLQSLQSELQFKDAEMNE------LRTKLQTSERANKLAAPSVS 221
>gi|18390347 ATR interacting protein isoform 1 [Homo sapiens]
Length = 791
Score = 41.6 bits (96), Expect = 0.004
Identities = 29/110 (26%), Positives = 48/110 (43%), Gaps = 6/110 (5%)
Query: 386 QQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQ 445
Q +E KEKM +E++ GE L+EQR + L EK + +
Sbjct: 118 QAQYKELKEKMKVMEEEVLIKNGEIKILRDSLHQTESVLEEQRRSHFLLEQEKTQALSDK 177
Query: 446 IEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQKIPGMTLS 495
+E KKL+ +Q+ Q + + E TKLQ + + K+ ++S
Sbjct: 178 EKEFSKKLQSLQSELQFKDAEMNE------LRTKLQTSERANKLAAPSVS 221
>gi|58530842 desmoplakin isoform II [Homo sapiens]
Length = 2272
Score = 41.2 bits (95), Expect = 0.005
Identities = 25/113 (22%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
Query: 377 DPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSA 436
D L R +S +A K+++ K++I + ++ + R E +K++ +RE S
Sbjct: 1235 DELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESERE----KSE 1290
Query: 437 EKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQKI 489
++ ++ +IE ++ ++K I+ + + D ET ET + + E K+
Sbjct: 1291 REKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQREIDKL 1343
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 41.2 bits (95), Expect = 0.005
Identities = 25/113 (22%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
Query: 377 DPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSA 436
D L R +S +A K+++ K++I + ++ + R E +K++ +RE S
Sbjct: 1834 DELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESERE----KSE 1889
Query: 437 EKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQKI 489
++ ++ +IE ++ ++K I+ + + D ET ET + + E K+
Sbjct: 1890 REKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQREIDKL 1942
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 41.2 bits (95), Expect = 0.005
Identities = 22/127 (17%), Positives = 63/127 (49%), Gaps = 19/127 (14%)
Query: 349 QQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVG 408
Q P + P + +PS+ H ++ +++ Q+ Q QQ ++++++ + I A
Sbjct: 570 QMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISA--- 626
Query: 409 EFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQ 468
++Q++ + SA+++ + Q+Q ++ +++ ++ Q QQ++ Q
Sbjct: 627 ----------------QQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQP 670
Query: 469 EETMPTK 475
+++P++
Sbjct: 671 AQSLPSQ 677
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 41.2 bits (95), Expect = 0.005
Identities = 28/109 (25%), Positives = 61/109 (55%), Gaps = 6/109 (5%)
Query: 373 KEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAEL 432
++ G+ +++Q ++ E++E+M +E++ GE + + E +K +EQ +
Sbjct: 206 EQMGEQEEQMQKQEEQMGEQEEQMRKQEEQM----GEQEEQVQKQEEQVQKQEEQMRKQE 261
Query: 433 LTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQ 481
E+ +M++Q E+M K+ + QT Q+E+TG+Q+E+ +E + Q
Sbjct: 262 EQMREQEEQMREQEEQMLKQKE--QTEQEEQTGEQEEQMREQEEQMREQ 308
Score = 38.9 bits (89), Expect = 0.026
Identities = 25/108 (23%), Positives = 58/108 (53%), Gaps = 7/108 (6%)
Query: 369 RKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQR 428
RK ++ G+ ++VQ ++ ++++E+M +E++ E E ++ ++K + ++
Sbjct: 230 RKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQ--EEQMREQEEQMLKQKEQTEQ 287
Query: 429 EAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKE 476
E + E+ E ++Q+ E E++++E QE +QEE M +E
Sbjct: 288 EEQTGEQEEQMREQEEQMREQEEQMRE-----QEEQMREQEEQMGKQE 330
Score = 35.8 bits (81), Expect = 0.22
Identities = 27/136 (19%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
Query: 341 TPYVEETAQQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCK 400
T E+T +Q + E R+ ++ + +++ ++ E+KE+M K
Sbjct: 285 TEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQK 344
Query: 401 EKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQ 460
E+++ + +E + + +++++Q E K+ E ++ EE +K +E Q
Sbjct: 345 EQMWKQEEQMGEQEEQMQKQEEQVRKQEE-----QMRKQEEQMRKQEEQMRKQEEQMGEQ 399
Query: 461 QERTGDQQEETMPTKE 476
+E+ G+Q+E+ +E
Sbjct: 400 KEQMGEQKEQMREQEE 415
Score = 33.9 bits (76), Expect = 0.83
Identities = 28/117 (23%), Positives = 60/117 (51%), Gaps = 16/117 (13%)
Query: 372 GKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAE 431
G++EG ++ ++ E++E+M +E++ GE + E RK+ ++ E E
Sbjct: 195 GEQEG----QMGEQEEQMGEQEEQMQKQEEQM----GE------QEEQMRKQEEQMGEQE 240
Query: 432 LLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQK 488
+K+ E ++ EE +K +E Q+E+ +Q+E+ + KE T+ + + Q+
Sbjct: 241 --EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQE 295
Score = 33.5 bits (75), Expect = 1.1
Identities = 22/108 (20%), Positives = 57/108 (52%), Gaps = 7/108 (6%)
Query: 369 RKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQR 428
+K ++ G+ ++++ ++ E++E++ +E++ + +E + ++++EQ
Sbjct: 216 QKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQE 275
Query: 429 EAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKE 476
E L +++ E ++Q E E++++E QE +QEE M +E
Sbjct: 276 EQML--KQKEQTEQEEQTGEQEEQMRE-----QEEQMREQEEQMREQE 316
Score = 32.0 bits (71), Expect = 3.1
Identities = 24/112 (21%), Positives = 56/112 (50%), Gaps = 12/112 (10%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
++++ ++ E++E+M+ KE+ EE E ++++EQ E ++ E+
Sbjct: 262 EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQ-EEQMREQEE-QMREQEEQM 319
Query: 440 AEMQKQIEEMEKKL----------KEIQTTQQERTGDQQEETMPTKETTKLQ 481
E ++Q+ + E+++ KE Q+E+ G+Q+E+ +E + Q
Sbjct: 320 REQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQ 371
Score = 31.2 bits (69), Expect = 5.4
Identities = 23/106 (21%), Positives = 56/106 (52%), Gaps = 3/106 (2%)
Query: 373 KEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAEL 432
KE+ + ++ ++ E++E+M +E++ + +E + +++ EQ+E ++
Sbjct: 282 KEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKE-QM 340
Query: 433 LTSAEKRAEMQKQIEEMEKKL--KEIQTTQQERTGDQQEETMPTKE 476
E+ + ++Q+ E E+++ +E Q +QE +QEE M +E
Sbjct: 341 WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQE 386
Score = 31.2 bits (69), Expect = 5.4
Identities = 19/93 (20%), Positives = 50/93 (53%), Gaps = 4/93 (4%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
+++ ++ E++E+M +E++ + +E + +++++Q E ++ E+
Sbjct: 345 EQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEE-QMGEQKEQM 403
Query: 440 AEMQKQIEEMEKKL---KEIQTTQQERTGDQQE 469
E ++Q+ E E+++ KE Q+E G+Q+E
Sbjct: 404 GEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 41.2 bits (95), Expect = 0.005
Identities = 25/99 (25%), Positives = 56/99 (56%), Gaps = 3/99 (3%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
++++ ++ ++E++EKM +EK+ + +E + +K++EQ E ++ EK
Sbjct: 599 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQ-EKKIREQEEKI 657
Query: 440 AEMQKQIEEMEKKL--KEIQTTQQERTGDQQEETMPTKE 476
E ++ ++E E+K+ +E + +QE +QEE M +E
Sbjct: 658 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 696
Score = 40.0 bits (92), Expect = 0.012
Identities = 34/121 (28%), Positives = 63/121 (52%), Gaps = 7/121 (5%)
Query: 373 KEEGDPLQRVQSHQQASEE---KKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQRE 429
++E + + R + + EE +KEK+ +EKI + +E + +K++EQ E
Sbjct: 519 RQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEE 578
Query: 430 AELLTSAEKRAEMQKQIEEMEKKLKEIQ--TTQQERTGDQQEETMPTKETTKLQIASESQ 487
++ EK E +++I E E+K++E + T +QE +QEE M +E K+Q E
Sbjct: 579 -KVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE-EKMQEQEEKM 636
Query: 488 K 488
+
Sbjct: 637 R 637
Score = 40.0 bits (92), Expect = 0.012
Identities = 27/107 (25%), Positives = 59/107 (55%), Gaps = 3/107 (2%)
Query: 368 TRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQ 427
T++ ++ G+ +++ ++ +E++EKM +EKI + +E + + ++EQ
Sbjct: 608 TQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 667
Query: 428 REAELLTSAEKRAEMQKQIEEMEKKLK--EIQTTQQERTGDQQEETM 472
E ++ EK E +++++E E+K++ E + +QE QQEE M
Sbjct: 668 EE-KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 713
Score = 38.9 bits (89), Expect = 0.026
Identities = 28/106 (26%), Positives = 58/106 (54%), Gaps = 10/106 (9%)
Query: 374 EEGDPLQRVQSHQQASEEK---KEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREA 430
E+ + ++R + EEK +E+MM+ KE+ + E E+ E R++ ++++E
Sbjct: 407 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ---EKIREQEEKRQEE 463
Query: 431 ELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKE 476
E + EKR E + ++ E+K++E Q+E+ +Q+E+ +E
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIRE----QEEKIREQEEKMWRQEE 505
Score = 38.1 bits (87), Expect = 0.044
Identities = 27/112 (24%), Positives = 59/112 (52%), Gaps = 6/112 (5%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
+++ ++ +++EKM +EK++ + +E + +K++EQ E ++ EK
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEE-KIREQEEKI 601
Query: 440 AEMQKQIEEMEKKL--KEIQTTQQERTGDQQEETMPTKETTKLQIASESQKI 489
E ++ +E E+K+ +E + +QE +QEE M +E +I + +KI
Sbjct: 602 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEE---KIREQEKKI 650
Score = 36.6 bits (83), Expect = 0.13
Identities = 25/112 (22%), Positives = 60/112 (53%), Gaps = 10/112 (8%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
+++Q ++ +E++EK+ +EKI + +E ++ K+ K +R+ E++ E++
Sbjct: 368 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE--EMMWEKEEKMRRQEEMMWEKEEK 425
Query: 440 A--------EMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIA 483
E +++I E+E+K+ E + +++ Q+EE + +E + Q A
Sbjct: 426 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 477
Score = 36.2 bits (82), Expect = 0.17
Identities = 26/112 (23%), Positives = 57/112 (50%), Gaps = 10/112 (8%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAE---VFRKKLKEQREAELLTSA 436
++++ ++ EK+EK+ +EK++ EE R E + ++ ++++EA++
Sbjct: 424 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 483
Query: 437 EKRAEMQKQIEE-------MEKKLKEIQTTQQERTGDQQEETMPTKETTKLQ 481
EK E +++I E E+K+ E + ++E +QEE +E + Q
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ 535
Score = 35.4 bits (80), Expect = 0.28
Identities = 25/112 (22%), Positives = 58/112 (51%), Gaps = 3/112 (2%)
Query: 373 KEEGDPLQRVQSHQQASEEK---KEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQRE 429
+E+ + ++ + + EEK +E+MM+ KE+ E +E+ ++++ ++E
Sbjct: 378 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 437
Query: 430 AELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQ 481
++ EK E +K E+ EK+ +E + +QE+ +Q+ + +E + Q
Sbjct: 438 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 489
Score = 35.4 bits (80), Expect = 0.28
Identities = 22/105 (20%), Positives = 57/105 (54%), Gaps = 8/105 (7%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQ------REAELL 433
+++ ++ +++EK+ +EK++ + +E + +K++EQ +E ++
Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMG 616
Query: 434 TSAEKRAEMQKQIEEMEKKLK--EIQTTQQERTGDQQEETMPTKE 476
EK E +++++E E+K++ E + +QE+ +QEE + +E
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 661
Score = 35.4 bits (80), Expect = 0.28
Identities = 26/108 (24%), Positives = 53/108 (49%), Gaps = 8/108 (7%)
Query: 377 DPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQ------REA 430
D ++++ ++ ++EK+ +EKI + +E + +K+ EQ +E
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 627
Query: 431 ELLTSAEKRAEMQKQIEEMEKKLKEIQ--TTQQERTGDQQEETMPTKE 476
++ EK +++I E EKK++E + +QE +QEE M +E
Sbjct: 628 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 675
Score = 34.3 bits (77), Expect = 0.63
Identities = 19/56 (33%), Positives = 34/56 (60%), Gaps = 2/56 (3%)
Query: 423 KLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQ--TTQQERTGDQQEETMPTKE 476
+L +Q+E ++ EK E +++I+E E+K++E + +QE +QEE M KE
Sbjct: 354 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 409
Score = 33.1 bits (74), Expect = 1.4
Identities = 33/124 (26%), Positives = 61/124 (49%), Gaps = 14/124 (11%)
Query: 373 KEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRK--KLKEQREA 430
KEE + H+Q ++E+ +EKI + +E A+++R+ K++EQ E
Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE---QEKRQEQEAKMWRQEEKIREQEEK 492
Query: 431 -----ELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASE 485
E + E++ Q++I E EK+ ++ + +QE +QEE KE +I +
Sbjct: 493 IREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE----KIHEQ 548
Query: 486 SQKI 489
+KI
Sbjct: 549 EEKI 552
Score = 32.0 bits (71), Expect = 3.1
Identities = 29/112 (25%), Positives = 53/112 (47%), Gaps = 17/112 (15%)
Query: 376 GDPLQRVQSHQQA-----------SEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKL 424
G LQ V + QA +++++EKM +EKI + +E + +K+
Sbjct: 332 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 391
Query: 425 KEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKE 476
+EQ E ++ EM + EE ++ +E+ ++E+ +QEE M KE
Sbjct: 392 REQEE-----KMRRQEEMMWEKEEKMRRQEEMMWEKEEKM-RRQEEMMWEKE 437
Score = 31.2 bits (69), Expect = 5.4
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 7/92 (7%)
Query: 390 EEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEM 449
EE KEK +EK+ E S EI+ V K K +R LL + +AE +E+
Sbjct: 278 EELKEKNAKLQEKLQLVESEKS--EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 335
Query: 450 EKKLKEIQTTQQE-----RTGDQQEETMPTKE 476
+ ++Q +E R QQEE M +E
Sbjct: 336 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQE 367
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 41.2 bits (95), Expect = 0.005
Identities = 31/114 (27%), Positives = 58/114 (50%), Gaps = 17/114 (14%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
+++ + ++ EEKK++ K+K R E R++ +E+REAEL E+
Sbjct: 809 RQLLAEKREQEEKKKQEEEEKKK-------------REEEERERERERREAELRAQQEEE 855
Query: 440 AEMQKQIEEMEKKLKEIQTT---QQERTGDQQEETMP-TKETTKLQIASESQKI 489
Q+++E ++K KE + T ++++ Q EE + KE LQ E Q++
Sbjct: 856 TRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQEL 909
Score = 37.4 bits (85), Expect = 0.075
Identities = 26/80 (32%), Positives = 43/80 (53%), Gaps = 6/80 (7%)
Query: 414 EIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMP 473
+I V+R+ L E+RE E +K+ E +K+ E E++ +E + + E Q+EET
Sbjct: 802 QIARRVYRQLLAEKREQE---EKKKQEEEEKKKREEEERERERERREAELRAQQEEETRK 858
Query: 474 TKETTKLQIASESQKIPGMT 493
+E LQ +SQK +T
Sbjct: 859 QQELEALQ---KSQKEAELT 875
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 40.8 bits (94), Expect = 0.007
Identities = 33/128 (25%), Positives = 64/128 (50%), Gaps = 15/128 (11%)
Query: 370 KPGKEEGDPLQRVQSHQQASEE---------KKEKMMYCKEKIYAGVGEFSFEEIRAEVF 420
KP ++ + V+S + SEE K+E + +E+ E EE+R E
Sbjct: 2208 KPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEE 2267
Query: 421 RKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKL 480
+K +E+ E + + ++ E +K+ ++ EKK +E+Q ++E +++EE M +ET L
Sbjct: 2268 ERKEEEEGEEKQV----EKEEEEKKKKKKEKKKEEVQ--EKEEVFEEKEEIMSEEETESL 2321
Query: 481 QIASESQK 488
E ++
Sbjct: 2322 SDEEEEEE 2329
Score = 36.6 bits (83), Expect = 0.13
Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 4/83 (4%)
Query: 373 KEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSF-EEIRAEVFRKKLKEQREAE 431
+EEG+ Q + ++ ++KKEK KE++ F EEI +E + L ++ E E
Sbjct: 2272 EEEGEEKQVEKEEEEKKKKKKEKK---KEEVQEKEEVFEEKEEIMSEEETESLSDEEEEE 2328
Query: 432 LLTSAEKRAEMQKQIEEMEKKLK 454
S E+ + +K+I + EK+ K
Sbjct: 2329 ESCSLEEEVDREKEILKKEKQFK 2351
Score = 32.3 bits (72), Expect = 2.4
Identities = 45/214 (21%), Positives = 83/214 (38%), Gaps = 22/214 (10%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
+R + ++ EE +E+ KE+ GE E E +KK KE +K+
Sbjct: 2250 EREEEEEREEEEVREEEEERKEE---EEGEEKQVEKEEEEKKKKKKE----------KKK 2296
Query: 440 AEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQKIPGMTLSSSVC 499
E+Q++ E E+K + + + E D++EE ++ E K
Sbjct: 2297 EEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQR 2356
Query: 500 QVNCCARETSLAENIWQEQPHSKGPSVPFSIFDEFLLS------EKKNKSP-PADPPRVL 552
+ + RE L +I + PH KG ++ + L E K K+P P ++
Sbjct: 2357 RKSLRGRERVL--SILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKTPVPVPEKQIS 2414
Query: 553 AQRRPLAVLKTSESITSNEDVSPDVCDEFTGIEP 586
+ + V++ D +V ++ I P
Sbjct: 2415 WEDKKATVVEIPRKFLGTMDKEREVMGKYEPIPP 2448
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 40.8 bits (94), Expect = 0.007
Identities = 28/110 (25%), Positives = 54/110 (49%), Gaps = 6/110 (5%)
Query: 373 KEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREA-- 430
KE + +++Q ++ E++EKM +EK++ +E + +K+++Q E
Sbjct: 341 KELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 400
Query: 431 ----ELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKE 476
L E+ E +K E++EK +E + +QE+ QEE M +E
Sbjct: 401 EQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEE 450
Score = 38.5 bits (88), Expect = 0.034
Identities = 36/119 (30%), Positives = 63/119 (52%), Gaps = 20/119 (16%)
Query: 373 KEEGDPLQRVQSHQQASEEK----KEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQR 428
+E+ + +Q + Q EEK +EKM +EK++ E +E+ +++L EQ+
Sbjct: 606 REQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE-EKMWEQEEKMWEQQRLPEQK 664
Query: 429 EA----ELLTSAEKRAEMQKQI---EEMEKKLKEIQTTQQERTGDQ----QEETMPTKE 476
E E + EK E +++I E+MEKK +E Q+++T DQ +EE+M +E
Sbjct: 665 EKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQE----QEKKTWDQEKMREEESMRERE 719
Score = 36.6 bits (83), Expect = 0.13
Identities = 25/99 (25%), Positives = 52/99 (52%), Gaps = 4/99 (4%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
+ ++ ++ +++EKM +E++ G+ +E + K+L+EQ + L EK
Sbjct: 279 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKE--LREQEKE 336
Query: 440 AEMQKQIEEMEKKLKEIQTT--QQERTGDQQEETMPTKE 476
QK++ E E++++E + +QE +QEE M +E
Sbjct: 337 LREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE 375
Score = 36.6 bits (83), Expect = 0.13
Identities = 28/85 (32%), Positives = 45/85 (52%), Gaps = 6/85 (7%)
Query: 386 QQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQ 445
+Q + ++EK M +EK E EE R KK++E+ E T E+ +MQKQ
Sbjct: 421 EQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEE----TMREQEEKMQKQ 476
Query: 446 IEEMEKKLKEIQTTQQERTGDQQEE 470
E M + +E + QQ+R +Q+E+
Sbjct: 477 EENMWE--QEEKEWQQQRLPEQKEK 499
Score = 36.6 bits (83), Expect = 0.13
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 7/119 (5%)
Query: 374 EEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELL 433
E+ + ++ + EE+ EK +EK E EE R KK++E+ E +
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM-MR 606
Query: 434 TSAEKRAEMQKQIEEMEKKL--KEIQTTQQERTGDQQEETMPTKETTKLQIASESQKIP 490
EK E +++++E E+K+ +E + +QE +QEE M +E + E Q++P
Sbjct: 607 EQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE----EKMWEQQRLP 661
Score = 36.2 bits (82), Expect = 0.17
Identities = 29/115 (25%), Positives = 55/115 (47%), Gaps = 6/115 (5%)
Query: 378 PLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAE 437
P Q+ + + +++EKM +EKI+ E E + + KK +Q + S
Sbjct: 661 PEQKEKLWEHEKMQEQEKMQEQEEKIW----EQEKMEKKTQEQEKKTWDQEKMREEESMR 716
Query: 438 KRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIAS--ESQKIP 490
+R + ++ EEM ++ +E Q+E+ +Q+EE +E Q E Q++P
Sbjct: 717 EREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLP 771
Score = 35.8 bits (81), Expect = 0.22
Identities = 23/100 (23%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
++++ ++ E++EKM +EK+ + +E + + +K+ EQ E ++ EK
Sbjct: 596 KKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE-KMWEQEEKM 654
Query: 440 AEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTK 479
E Q+ E+ EK + + +QE+ +Q+E+ ++ K
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEK 694
Score = 35.4 bits (80), Expect = 0.28
Identities = 24/114 (21%), Positives = 57/114 (50%), Gaps = 5/114 (4%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQRE-----AELLT 434
+R++ ++ E++E M +EK+ + +E + +K++EQ E E +
Sbjct: 589 ERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMW 648
Query: 435 SAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQK 488
E++ Q+++ E ++KL E + Q++ +QEE + +E + + + +K
Sbjct: 649 EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702
Score = 35.0 bits (79), Expect = 0.37
Identities = 31/139 (22%), Positives = 64/139 (46%), Gaps = 16/139 (11%)
Query: 366 LSTRKPGKEEGDPLQRVQSHQQASEEK----KEKMMYCKEKIYAGVGEFSFEEIRA---- 417
L +K +E+ + +Q + EEK +EKM +E+++ + +E +
Sbjct: 337 LREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 396
Query: 418 -------EVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLK-EIQTTQQERTGDQQE 469
E R+K + RE E + ++ +K+++E EKK + + + Q+E ++E
Sbjct: 397 ERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRERE 456
Query: 470 ETMPTKETTKLQIASESQK 488
+ M +E T + + QK
Sbjct: 457 KKMREEEETMREQEEKMQK 475
Score = 33.9 bits (76), Expect = 0.83
Identities = 24/104 (23%), Positives = 53/104 (50%), Gaps = 7/104 (6%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQR-----EAELLT 434
+++ ++ E++ KM +EK++ +E K+L+EQ+ E ++
Sbjct: 293 EKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQE 352
Query: 435 SAEKRAEMQKQIEEMEKKL--KEIQTTQQERTGDQQEETMPTKE 476
EK E ++++ E E+K+ +E + +QE+ +QE+ M +E
Sbjct: 353 QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 396
Score = 33.9 bits (76), Expect = 0.83
Identities = 21/107 (19%), Positives = 53/107 (49%), Gaps = 3/107 (2%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
+R+ ++ E+++KM +E+++ +E R R++ K + E + +K
Sbjct: 376 ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEER---MREQEKMWEQVEKMREEKKM 432
Query: 440 AEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASES 486
E +K+ + E+K++E + ++ ++EE ++ K+Q E+
Sbjct: 433 QEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 479
Score = 33.5 bits (75), Expect = 1.1
Identities = 27/101 (26%), Positives = 54/101 (53%), Gaps = 4/101 (3%)
Query: 379 LQRVQSH--QQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSA 436
L +VQ++ Q+ ++E++ ++KI + +E R K++EQ E ++
Sbjct: 262 LPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEE-KMWRQE 320
Query: 437 EKRAEMQKQIEEMEKKLKE-IQTTQQERTGDQQEETMPTKE 476
++ E +K++ E EK+L+E + +QE +QEE M +E
Sbjct: 321 KRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQE 361
Score = 33.5 bits (75), Expect = 1.1
Identities = 32/131 (24%), Positives = 66/131 (50%), Gaps = 26/131 (19%)
Query: 369 RKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQR 428
R+ ++ D +R+ + EK+E+M +EK++ V E++R E KK++EQ
Sbjct: 386 REQEQKMRDQEERMWEQDERLREKEERMRE-QEKMWEQV-----EKMREE---KKMQEQE 436
Query: 429 EAELLTSAEKRAEMQKQIEEMEKKLKEIQTT----------QQERTGDQQEETMPTKETT 478
+ E++ + +++I E EKK++E + T Q+E +Q+E KE
Sbjct: 437 KKT--RDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE-----KEWQ 489
Query: 479 KLQIASESQKI 489
+ ++ + +K+
Sbjct: 490 QQRLPEQKEKL 500
Score = 32.7 bits (73), Expect = 1.8
Identities = 21/91 (23%), Positives = 53/91 (58%), Gaps = 4/91 (4%)
Query: 386 QQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQ 445
Q+ +E++EK+ +EKI + E+ +++R++ ++E ++ EK + +++
Sbjct: 503 QEKMQEQEEKIWEQEEKIRDQEEMWGQEK---KMWRQEKMREQEDQMWEQEEKMRDQEQK 559
Query: 446 IEEMEKKLKEIQTTQQERTGDQQEETMPTKE 476
+ + E+++++ +T +QE+ QEE M +E
Sbjct: 560 MWDQEERMEK-KTQEQEKKTWDQEEKMREEE 589
Score = 32.3 bits (72), Expect = 2.4
Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 17/111 (15%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
+R++ ++ E++E M +EK+ E +E+ E +++L EQ+E L EK
Sbjct: 450 ERIREREKKMREEEETMREQEEKMQKQE-ENMWEQEEKEWQQQRLPEQKEK--LWEQEKM 506
Query: 440 AEMQKQIEEMEKKLK--------EIQTTQQERTGDQ------QEETMPTKE 476
E +++I E E+K++ E + +QE+ +Q QEE M +E
Sbjct: 507 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 557
Score = 32.3 bits (72), Expect = 2.4
Identities = 21/97 (21%), Positives = 49/97 (50%), Gaps = 9/97 (9%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
++++ ++ E++EKM +EK+ +E E++ ++ K + E + ++
Sbjct: 720 KKMREEEEMMREQEEKMQEQEEKM---------QEQEEEMWEQEEKMWEQEEKMWEQQRL 770
Query: 440 AEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKE 476
E ++++ E EK ++ + +QE QEE M +E
Sbjct: 771 PEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE 807
Score = 31.6 bits (70), Expect = 4.1
Identities = 24/100 (24%), Positives = 54/100 (54%), Gaps = 7/100 (7%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
+++Q ++ +E++E+M +EK++ E +E+ R ++KL E E + EK
Sbjct: 734 EKMQEQEEKMQEQEEEMWEQEEKMWEQE-EKMWEQQRLPEQKEKLWEH---EKMQEQEKI 789
Query: 440 AEMQKQIEEMEKKLK---EIQTTQQERTGDQQEETMPTKE 476
E ++++ + E+K++ E Q+E+ Q+E+ +E
Sbjct: 790 WEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEE 829
Score = 31.2 bits (69), Expect = 5.4
Identities = 22/102 (21%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
Q +++ E+++KM +E + + +E + + +++ EQ E ++ EK
Sbjct: 706 QEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEE-KMWEQEEKM 764
Query: 440 AEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQ 481
E Q+ E+ EK + + +QE+ +Q+E+ +E + Q
Sbjct: 765 WEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ 806
Score = 30.8 bits (68), Expect = 7.0
Identities = 23/97 (23%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
Query: 380 QRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKR 439
+++Q ++ + +++EKM +E+I + EE +K+++Q E + EK
Sbjct: 430 KKMQEQEKKTRDQEEKMQE-EERIREREKKMREEEETMREQEEKMQKQEE-NMWEQEEKE 487
Query: 440 AEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKE 476
+ Q+ E+ EK ++ + +QE +QEE + +E
Sbjct: 488 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 524
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 40.8 bits (94), Expect = 0.007
Identities = 70/335 (20%), Positives = 135/335 (40%), Gaps = 69/335 (20%)
Query: 160 EEYEARENFRKADAIFQEGIQQK-AEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFE 218
EE E + K+D + G +++ + E + + + +A + A E+++ EE E
Sbjct: 534 EEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSE 593
Query: 219 SSVPQRSTLAELKSKGKKTARAPIIRV-------GGALKAPSQNRGLQNPFPQQ-MQNNS 270
+ +A+ K + + A++P+ + K+P + +G ++P P+ ++
Sbjct: 594 EVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKG-KSPVPKSPVEEKG 652
Query: 271 RITVFDENADEASTAELSKPTVQPWIAPPMPRA-------------------KENELQAG 311
+ V +E + +SK V+ P+P++ +E E++
Sbjct: 653 KSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEA 712
Query: 312 PWNTG-RSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQQPVMTPCKIEPSINHILSTRK 370
P E +P+ VP + +P EE + V ++ + K
Sbjct: 713 PKEEKVEKKEEKPKD-------VPEKKKAESPVKEEAVAEVVTITKSVKVHLE------K 759
Query: 371 PGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREA 430
KEEG PLQ+ E++KEK AG GE EE E K K R+
Sbjct: 760 ETKEEGKPLQQ--------EKEKEK---------AG-GEGGSEE---EGSDKGAKGSRKE 798
Query: 431 ELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTG 465
++ + E + EE+E++ KE + ++E G
Sbjct: 799 DIAVNGEVEGK-----EEVEQETKEKGSGREEEKG 828
Score = 32.0 bits (71), Expect = 3.1
Identities = 77/426 (18%), Positives = 158/426 (37%), Gaps = 49/426 (11%)
Query: 175 FQEGIQQKAEPLERLQ---SQH-RQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAEL 230
+Q+ IQQ L + ++H R++Q ++ + L +E ++ E + ST A
Sbjct: 359 YQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGS 418
Query: 231 KSKGKKTARAPIIRVGGALKAP---SQNRGLQNPFPQQMQNNSRITVFDENADEASTAEL 287
+ T R PI + ++ P + +Q+ F +++ +++ +EA TA
Sbjct: 419 ITGPLYTHRPPIT-ISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAIT 477
Query: 288 SKPTVQPWIAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEET 347
+ V KE + +A E P + A + + + P V+E
Sbjct: 478 EELAVS---------MKEEKKEAA-----EEKEEEPEAEEEEVAAKKSPVKATAPEVKEE 523
Query: 348 AQQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGV 407
+ E + + D + S ++ S EK+E G
Sbjct: 524 EGEK-------EEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQE------EGE 570
Query: 408 GEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQ 467
E E AE +K E++ E+ T E A+ + +E+ EK + + E G
Sbjct: 571 TEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAK--VEKPEKAKSPVPKSPVEEKGKS 628
Query: 468 QEETMPTKETTKLQIASESQKIPGMT-LSSSVCQVNCCARETSLAENIWQEQPHSKGPSV 526
P +E K + + G + + S + ++ ++++ +E+ S P
Sbjct: 629 PVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK---GKSPVSKSPVEEKAKSPVPKS 685
Query: 527 PFSIFDEFLLSEKKNKSPPADPPRVLAQRRPLAVLKTSESITSNEDVSPDVCDEFTGIEP 586
P + E K+K+ + + + + E + E+ DV ++ P
Sbjct: 686 P--------VEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESP 737
Query: 587 LSEDAI 592
+ E+A+
Sbjct: 738 VKEEAV 743
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 40.8 bits (94), Expect = 0.007
Identities = 70/335 (20%), Positives = 135/335 (40%), Gaps = 69/335 (20%)
Query: 160 EEYEARENFRKADAIFQEGIQQK-AEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFE 218
EE E + K+D + G +++ + E + + + +A + A E+++ EE E
Sbjct: 158 EEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSE 217
Query: 219 SSVPQRSTLAELKSKGKKTARAPIIRV-------GGALKAPSQNRGLQNPFPQQ-MQNNS 270
+ +A+ K + + A++P+ + K+P + +G ++P P+ ++
Sbjct: 218 EVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKG-KSPVPKSPVEEKG 276
Query: 271 RITVFDENADEASTAELSKPTVQPWIAPPMPRA-------------------KENELQAG 311
+ V +E + +SK V+ P+P++ +E E++
Sbjct: 277 KSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEA 336
Query: 312 PWNTG-RSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQQPVMTPCKIEPSINHILSTRK 370
P E +P+ VP + +P EE + V ++ + K
Sbjct: 337 PKEEKVEKKEEKPKD-------VPEKKKAESPVKEEAVAEVVTITKSVKVHLE------K 383
Query: 371 PGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREA 430
KEEG PLQ+ E++KEK AG GE EE E K K R+
Sbjct: 384 ETKEEGKPLQQ--------EKEKEK---------AG-GEGGSEE---EGSDKGAKGSRKE 422
Query: 431 ELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTG 465
++ + E + EE+E++ KE + ++E G
Sbjct: 423 DIAVNGEVEGK-----EEVEQETKEKGSGREEEKG 452
Score = 30.4 bits (67), Expect = 9.1
Identities = 71/403 (17%), Positives = 147/403 (36%), Gaps = 45/403 (11%)
Query: 194 RQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAP- 252
R++Q ++ + L +E ++ E + ST A + T R PI + ++ P
Sbjct: 6 REYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPIT-ISSKIQKPK 64
Query: 253 --SQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQA 310
+ +Q+ F +++ +++ +EA TA + V KE + +A
Sbjct: 65 VEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVS---------MKEEKKEA 115
Query: 311 GPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQQPVMTPCKIEPSINHILSTRK 370
E P + A + + + P V+E + E +
Sbjct: 116 A-----EEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEK-------EEEEGQEEEEEE 163
Query: 371 PGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREA 430
+ D + S ++ S EK+E G E E AE +K E++
Sbjct: 164 DEGAKSDQAEEGGSEKEGSSEKEEGEQE------EGETEAEAEGEEAEAKEEKKVEEKSE 217
Query: 431 ELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQKIP 490
E+ T E A+ + +E+ EK + + E G P +E K + +
Sbjct: 218 EVATKEELVADAK--VEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 275
Query: 491 GMT-LSSSVCQVNCCARETSLAENIWQEQPHSKGPSVPFSIFDEFLLSEKKNKSPPADPP 549
G + + S + ++ ++++ +E+ S P P + E K+K+
Sbjct: 276 GKSPVPKSPVEEK---GKSPVSKSPVEEKAKSPVPKSP--------VEEAKSKAEVGKGE 324
Query: 550 RVLAQRRPLAVLKTSESITSNEDVSPDVCDEFTGIEPLSEDAI 592
+ + + + E + E+ DV ++ P+ E+A+
Sbjct: 325 QKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAV 367
>gi|23943882 serine/threonine kinase 33 [Homo sapiens]
Length = 514
Score = 40.8 bits (94), Expect = 0.007
Identities = 45/172 (26%), Positives = 82/172 (47%), Gaps = 10/172 (5%)
Query: 844 LQDLLQHSEYITHEITVLIIYNLLTIVEMLHKAEIVHGDLSPRCLILRNRIHDPYDCNKN 903
L+++L + + T II +L + + LH +IVH DL +++++ + D D N+
Sbjct: 200 LKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLID--DNNEI 257
Query: 904 NQALKIVDFSYSVDLRVQLDVFTLSGFRTVQILEGQKILANCSSPYQVDLFGIADLAHLL 963
N +K+ DF +V + + + + T + + I A+ S Q D++ I + ++L
Sbjct: 258 NLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYS-QQCDIWSIGVVMYML 316
Query: 964 LFKEHLQVFWDGSFWKLSQNISELKDGELWNKFFVRILNANDEATVSVLGEL 1015
L E F S KL + I + GEL F + N+ + SVL +L
Sbjct: 317 LRGE--PPFLASSEEKLFELI---RKGEL--HFENAVWNSISDCAKSVLKQL 361
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 40.8 bits (94), Expect = 0.007
Identities = 85/468 (18%), Positives = 172/468 (36%), Gaps = 34/468 (7%)
Query: 33 RQGRIMSTLQGALAQESACNNTLQQQKRAFEYEIRFYTGNDPLDVW---DRYISWTEQNY 89
R +++ Q LAQ L+Q R Y + DPL W R Q
Sbjct: 1180 RVAQLLERWQAVLAQTDVRQRELEQLGRQLRY---YRESADPLGAWLQDARRRQEQIQAM 1236
Query: 90 PQGGKESNMSTLL-------------ERAVEALQGEKRYYSDPRFLNLWLKLGRLCNEPL 136
P ++ L E+ E + K+Y + + L L + EP+
Sbjct: 1237 PLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPV 1296
Query: 137 DMYSYLHN-QGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQQKAEPLERLQSQHRQ 195
+ Q S+ Q Y+ Y F ++ E ERL Q R
Sbjct: 1297 ASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA 1356
Query: 196 FQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQN 255
+ + ALEK+ + + ++ E K ++ + R A+ A Q
Sbjct: 1357 EERERLAEVEAALEKQRQLAEAHAQAKAQAE-REAKELQQRMQEEVVRREEAAVDAQQQK 1415
Query: 256 RGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQ-AGPWN 314
R +Q QQ++ +S + A +A AE S+ ++ I + + E Q G
Sbjct: 1416 RSIQEEL-QQLRQSSEAEI-QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1473
Query: 315 TGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKE 374
++L R A V++ +Q+ ++ + + + + +E
Sbjct: 1474 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVEL---ASRVKAEAEAARE 1530
Query: 375 EGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLT 434
+ LQ ++ + +EE + ++ A V ++ E ++ + + +++ +
Sbjct: 1531 KQRALQALEELRLQAEEAERRLR------QAEVERARQVQVALETAQRSAEAELQSKRAS 1584
Query: 435 SAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQI 482
AEK A++++ ++E + +++ + ER QQ E +E + ++
Sbjct: 1585 FAEKTAQLERSLQEEHVAVAQLR-EEAERRAQQQAEAERAREEAEREL 1631
Score = 33.5 bits (75), Expect = 1.1
Identities = 68/334 (20%), Positives = 133/334 (39%), Gaps = 35/334 (10%)
Query: 176 QEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAE--LKSK 233
Q +Q++AE ++++ + +R ++ A E ++ E + Q+ LAE LK K
Sbjct: 2263 QRFLQEEAEKMKQVAEE-------AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2315
Query: 234 GKKTARAPIIRVGGALK------APSQNRGLQNPFPQQMQNNSRITVFDENADEA----- 282
+ A ++ L A Q R LQ Q Q + T + EA
Sbjct: 2316 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQ 2375
Query: 283 ----STAELSKPTVQPWIAPPMPRAKEN--ELQAGPWNTGRSLEHRPRGNTASLIAVPAV 336
+ AE K V ++ RA+E+ + G L HR T + +
Sbjct: 2376 LEMSAEAERLKLRVAE-MSRAQARAEEDAQRFRKQAEEIGEKL-HRTELATQEKVTLVQT 2433
Query: 337 LPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKM 396
L + A++ ++E + K + + + +Q VQ Q E + +
Sbjct: 2434 LEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQ 2493
Query: 397 MYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEI 456
+ EK E E+ +A KL++ + E+ + + R E Q+Q ++ME++ + +
Sbjct: 2494 SFLSEKDSLLQRERFIEQEKA-----KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRL 2548
Query: 457 QTTQQE--RTGDQQEETMPTKETTKLQIASESQK 488
+ +E R + EE + K+ Q+ + ++
Sbjct: 2549 VASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2582
Score = 32.3 bits (72), Expect = 2.4
Identities = 62/319 (19%), Positives = 128/319 (40%), Gaps = 31/319 (9%)
Query: 176 QEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGK 235
+E QQK+ + Q + + R+ + + E+ E + ++ LAE ++ +
Sbjct: 1649 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1708
Query: 236 KTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPW 295
A +IR+ + Q R L ++Q + EA A++
Sbjct: 1709 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV-------- 1760
Query: 296 IAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQ-QPVMT 354
RA+ L A + R+ E + S + A F EE A+ + +
Sbjct: 1761 ------RAEMEVLLA---SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE 1811
Query: 355 PCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEE 414
K + + + R+ + E +++ + +A+ K E + KEK E E
Sbjct: 1812 EAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK------EAENER 1865
Query: 415 IRA----EVF-RKKLKEQREAELLTSAEKRAEMQKQIE-EMEKKLKEIQTTQQERTGDQQ 468
+R E F R++L+EQ E+ A+++K + E+E++ ++ T ++R +
Sbjct: 1866 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR-QVE 1924
Query: 469 EETMPTKETTKLQIASESQ 487
EE + K + + A +++
Sbjct: 1925 EEILALKASFEKAAAGKAE 1943
Score = 31.6 bits (70), Expect = 4.1
Identities = 28/114 (24%), Positives = 56/114 (49%), Gaps = 14/114 (12%)
Query: 379 LQRVQSHQQASEEKKEKMMYCKEKIYAGVGE----FSFEEIRAEVFRKKLK------EQR 428
LQ Q+ QQ+ +K+ ++ + I + F E +A+ R++ + EQ
Sbjct: 2485 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2544
Query: 429 EAELLTSAEKRAEMQKQIEE-MEKKLKEIQTTQQERTGDQQEETMPTKETTKLQ 481
L+ S E+ Q + EE + +K +E+Q +Q+R +Q+E + +E +L+
Sbjct: 2545 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR---RQQEELLAEENQRLR 2595
Score = 31.2 bits (69), Expect = 5.4
Identities = 66/342 (19%), Positives = 127/342 (37%), Gaps = 30/342 (8%)
Query: 163 EARENFRKADAIFQEGIQQKAE---PLERLQSQ-------HRQFQARVSRQTLLALEKEE 212
+ E A F++ KAE L R++S Q + +RQ LA E+E
Sbjct: 1922 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1981
Query: 213 EEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRI 272
E V + E ++ +K A + R+ ++ + R L+ Q+ ++
Sbjct: 1982 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQLQL 2038
Query: 273 TVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIA 332
A EA+ L A + KE ELQ L+ A+ A
Sbjct: 2039 ------AQEAAQKRLQAEEKAHAFA---VQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2089
Query: 333 VPAVLPSFTPYVEETAQ--QPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASE 390
+ E AQ + V +++ S R + + L R ++ Q+A+
Sbjct: 2090 AEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL-RKEAEQEAAR 2148
Query: 391 EKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEME 450
+ + ++K A ++ + R+K + ++E L + + QK + + E
Sbjct: 2149 RAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2208
Query: 451 KKLKEIQTTQQERTGDQQEETM-----PTKETTKLQIASESQ 487
+ + + T+ R Q EE + +E +KL+ E++
Sbjct: 2209 LQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2250
Score = 30.8 bits (68), Expect = 7.0
Identities = 25/157 (15%), Positives = 77/157 (49%), Gaps = 14/157 (8%)
Query: 334 PAVLPSFTPYVEETAQQPVMTPCKIEPSINHILS-TRKPGKEEGDPLQRVQSHQQASEEK 392
P P+ P V+ ++ + + + + + T + K + L+R++ ++ +E++
Sbjct: 1295 PVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQ 1354
Query: 393 KEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRA-EMQKQIEEMEK 451
+ + +E++ E+ A + +++ + A+ AE+ A E+Q++++E
Sbjct: 1355 RAEE---RERL---------AEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVV 1402
Query: 452 KLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQK 488
+ +E Q++ QEE +++++ +I +++++
Sbjct: 1403 RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQ 1439
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 40.8 bits (94), Expect = 0.007
Identities = 85/468 (18%), Positives = 172/468 (36%), Gaps = 34/468 (7%)
Query: 33 RQGRIMSTLQGALAQESACNNTLQQQKRAFEYEIRFYTGNDPLDVW---DRYISWTEQNY 89
R +++ Q LAQ L+Q R Y + DPL W R Q
Sbjct: 1184 RVAQLLERWQAVLAQTDVRQRELEQLGRQLRY---YRESADPLGAWLQDARRRQEQIQAM 1240
Query: 90 PQGGKESNMSTLL-------------ERAVEALQGEKRYYSDPRFLNLWLKLGRLCNEPL 136
P ++ L E+ E + K+Y + + L L + EP+
Sbjct: 1241 PLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPV 1300
Query: 137 DMYSYLHN-QGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQQKAEPLERLQSQHRQ 195
+ Q S+ Q Y+ Y F ++ E ERL Q R
Sbjct: 1301 ASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA 1360
Query: 196 FQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQN 255
+ + ALEK+ + + ++ E K ++ + R A+ A Q
Sbjct: 1361 EERERLAEVEAALEKQRQLAEAHAQAKAQAE-REAKELQQRMQEEVVRREEAAVDAQQQK 1419
Query: 256 RGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQ-AGPWN 314
R +Q QQ++ +S + A +A AE S+ ++ I + + E Q G
Sbjct: 1420 RSIQEEL-QQLRQSSEAEI-QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1477
Query: 315 TGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKE 374
++L R A V++ +Q+ ++ + + + + +E
Sbjct: 1478 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVEL---ASRVKAEAEAARE 1534
Query: 375 EGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLT 434
+ LQ ++ + +EE + ++ A V ++ E ++ + + +++ +
Sbjct: 1535 KQRALQALEELRLQAEEAERRLR------QAEVERARQVQVALETAQRSAEAELQSKRAS 1588
Query: 435 SAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQI 482
AEK A++++ ++E + +++ + ER QQ E +E + ++
Sbjct: 1589 FAEKTAQLERSLQEEHVAVAQLR-EEAERRAQQQAEAERAREEAEREL 1635
Score = 33.5 bits (75), Expect = 1.1
Identities = 68/334 (20%), Positives = 133/334 (39%), Gaps = 35/334 (10%)
Query: 176 QEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAE--LKSK 233
Q +Q++AE ++++ + +R ++ A E ++ E + Q+ LAE LK K
Sbjct: 2267 QRFLQEEAEKMKQVAEE-------AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2319
Query: 234 GKKTARAPIIRVGGALK------APSQNRGLQNPFPQQMQNNSRITVFDENADEA----- 282
+ A ++ L A Q R LQ Q Q + T + EA
Sbjct: 2320 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQ 2379
Query: 283 ----STAELSKPTVQPWIAPPMPRAKEN--ELQAGPWNTGRSLEHRPRGNTASLIAVPAV 336
+ AE K V ++ RA+E+ + G L HR T + +
Sbjct: 2380 LEMSAEAERLKLRVAE-MSRAQARAEEDAQRFRKQAEEIGEKL-HRTELATQEKVTLVQT 2437
Query: 337 LPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKM 396
L + A++ ++E + K + + + +Q VQ Q E + +
Sbjct: 2438 LEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQ 2497
Query: 397 MYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEI 456
+ EK E E+ +A KL++ + E+ + + R E Q+Q ++ME++ + +
Sbjct: 2498 SFLSEKDSLLQRERFIEQEKA-----KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRL 2552
Query: 457 QTTQQE--RTGDQQEETMPTKETTKLQIASESQK 488
+ +E R + EE + K+ Q+ + ++
Sbjct: 2553 VASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2586
Score = 32.3 bits (72), Expect = 2.4
Identities = 62/319 (19%), Positives = 128/319 (40%), Gaps = 31/319 (9%)
Query: 176 QEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGK 235
+E QQK+ + Q + + R+ + + E+ E + ++ LAE ++ +
Sbjct: 1653 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1712
Query: 236 KTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPW 295
A +IR+ + Q R L ++Q + EA A++
Sbjct: 1713 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV-------- 1764
Query: 296 IAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQ-QPVMT 354
RA+ L A + R+ E + S + A F EE A+ + +
Sbjct: 1765 ------RAEMEVLLA---SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE 1815
Query: 355 PCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEE 414
K + + + R+ + E +++ + +A+ K E + KEK E E
Sbjct: 1816 EAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK------EAENER 1869
Query: 415 IRA----EVF-RKKLKEQREAELLTSAEKRAEMQKQIE-EMEKKLKEIQTTQQERTGDQQ 468
+R E F R++L+EQ E+ A+++K + E+E++ ++ T ++R +
Sbjct: 1870 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR-QVE 1928
Query: 469 EETMPTKETTKLQIASESQ 487
EE + K + + A +++
Sbjct: 1929 EEILALKASFEKAAAGKAE 1947
Score = 31.6 bits (70), Expect = 4.1
Identities = 28/114 (24%), Positives = 56/114 (49%), Gaps = 14/114 (12%)
Query: 379 LQRVQSHQQASEEKKEKMMYCKEKIYAGVGE----FSFEEIRAEVFRKKLK------EQR 428
LQ Q+ QQ+ +K+ ++ + I + F E +A+ R++ + EQ
Sbjct: 2489 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2548
Query: 429 EAELLTSAEKRAEMQKQIEE-MEKKLKEIQTTQQERTGDQQEETMPTKETTKLQ 481
L+ S E+ Q + EE + +K +E+Q +Q+R +Q+E + +E +L+
Sbjct: 2549 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR---RQQEELLAEENQRLR 2599
Score = 31.2 bits (69), Expect = 5.4
Identities = 66/342 (19%), Positives = 127/342 (37%), Gaps = 30/342 (8%)
Query: 163 EARENFRKADAIFQEGIQQKAE---PLERLQSQ-------HRQFQARVSRQTLLALEKEE 212
+ E A F++ KAE L R++S Q + +RQ LA E+E
Sbjct: 1926 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1985
Query: 213 EEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRI 272
E V + E ++ +K A + R+ ++ + R L+ Q+ ++
Sbjct: 1986 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQLQL 2042
Query: 273 TVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIA 332
A EA+ L A + KE ELQ L+ A+ A
Sbjct: 2043 ------AQEAAQKRLQAEEKAHAFA---VQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2093
Query: 333 VPAVLPSFTPYVEETAQ--QPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASE 390
+ E AQ + V +++ S R + + L R ++ Q+A+
Sbjct: 2094 AEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL-RKEAEQEAAR 2152
Query: 391 EKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEME 450
+ + ++K A ++ + R+K + ++E L + + QK + + E
Sbjct: 2153 RAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2212
Query: 451 KKLKEIQTTQQERTGDQQEETM-----PTKETTKLQIASESQ 487
+ + + T+ R Q EE + +E +KL+ E++
Sbjct: 2213 LQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2254
Score = 30.8 bits (68), Expect = 7.0
Identities = 25/157 (15%), Positives = 77/157 (49%), Gaps = 14/157 (8%)
Query: 334 PAVLPSFTPYVEETAQQPVMTPCKIEPSINHILS-TRKPGKEEGDPLQRVQSHQQASEEK 392
P P+ P V+ ++ + + + + + T + K + L+R++ ++ +E++
Sbjct: 1299 PVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQ 1358
Query: 393 KEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRA-EMQKQIEEMEK 451
+ + +E++ E+ A + +++ + A+ AE+ A E+Q++++E
Sbjct: 1359 RAEE---RERL---------AEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVV 1406
Query: 452 KLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQK 488
+ +E Q++ QEE +++++ +I +++++
Sbjct: 1407 RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQ 1443
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 40.8 bits (94), Expect = 0.007
Identities = 85/468 (18%), Positives = 172/468 (36%), Gaps = 34/468 (7%)
Query: 33 RQGRIMSTLQGALAQESACNNTLQQQKRAFEYEIRFYTGNDPLDVW---DRYISWTEQNY 89
R +++ Q LAQ L+Q R Y + DPL W R Q
Sbjct: 1180 RVAQLLERWQAVLAQTDVRQRELEQLGRQLRY---YRESADPLGAWLQDARRRQEQIQAM 1236
Query: 90 PQGGKESNMSTLL-------------ERAVEALQGEKRYYSDPRFLNLWLKLGRLCNEPL 136
P ++ L E+ E + K+Y + + L L + EP+
Sbjct: 1237 PLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPV 1296
Query: 137 DMYSYLHN-QGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQQKAEPLERLQSQHRQ 195
+ Q S+ Q Y+ Y F ++ E ERL Q R
Sbjct: 1297 ASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA 1356
Query: 196 FQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQN 255
+ + ALEK+ + + ++ E K ++ + R A+ A Q
Sbjct: 1357 EERERLAEVEAALEKQRQLAEAHAQAKAQAE-REAKELQQRMQEEVVRREEAAVDAQQQK 1415
Query: 256 RGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQ-AGPWN 314
R +Q QQ++ +S + A +A AE S+ ++ I + + E Q G
Sbjct: 1416 RSIQEEL-QQLRQSSEAEI-QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1473
Query: 315 TGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKE 374
++L R A V++ +Q+ ++ + + + + +E
Sbjct: 1474 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVEL---ASRVKAEAEAARE 1530
Query: 375 EGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLT 434
+ LQ ++ + +EE + ++ A V ++ E ++ + + +++ +
Sbjct: 1531 KQRALQALEELRLQAEEAERRLR------QAEVERARQVQVALETAQRSAEAELQSKRAS 1584
Query: 435 SAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQI 482
AEK A++++ ++E + +++ + ER QQ E +E + ++
Sbjct: 1585 FAEKTAQLERSLQEEHVAVAQLR-EEAERRAQQQAEAERAREEAEREL 1631
Score = 33.5 bits (75), Expect = 1.1
Identities = 68/334 (20%), Positives = 133/334 (39%), Gaps = 35/334 (10%)
Query: 176 QEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAE--LKSK 233
Q +Q++AE ++++ + +R ++ A E ++ E + Q+ LAE LK K
Sbjct: 2263 QRFLQEEAEKMKQVAEE-------AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2315
Query: 234 GKKTARAPIIRVGGALK------APSQNRGLQNPFPQQMQNNSRITVFDENADEA----- 282
+ A ++ L A Q R LQ Q Q + T + EA
Sbjct: 2316 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQ 2375
Query: 283 ----STAELSKPTVQPWIAPPMPRAKEN--ELQAGPWNTGRSLEHRPRGNTASLIAVPAV 336
+ AE K V ++ RA+E+ + G L HR T + +
Sbjct: 2376 LEMSAEAERLKLRVAE-MSRAQARAEEDAQRFRKQAEEIGEKL-HRTELATQEKVTLVQT 2433
Query: 337 LPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKM 396
L + A++ ++E + K + + + +Q VQ Q E + +
Sbjct: 2434 LEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQ 2493
Query: 397 MYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEI 456
+ EK E E+ +A KL++ + E+ + + R E Q+Q ++ME++ + +
Sbjct: 2494 SFLSEKDSLLQRERFIEQEKA-----KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRL 2548
Query: 457 QTTQQE--RTGDQQEETMPTKETTKLQIASESQK 488
+ +E R + EE + K+ Q+ + ++
Sbjct: 2549 VASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2582
Score = 32.3 bits (72), Expect = 2.4
Identities = 62/319 (19%), Positives = 128/319 (40%), Gaps = 31/319 (9%)
Query: 176 QEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGK 235
+E QQK+ + Q + + R+ + + E+ E + ++ LAE ++ +
Sbjct: 1649 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1708
Query: 236 KTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPW 295
A +IR+ + Q R L ++Q + EA A++
Sbjct: 1709 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV-------- 1760
Query: 296 IAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQ-QPVMT 354
RA+ L A + R+ E + S + A F EE A+ + +
Sbjct: 1761 ------RAEMEVLLA---SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE 1811
Query: 355 PCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEE 414
K + + + R+ + E +++ + +A+ K E + KEK E E
Sbjct: 1812 EAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK------EAENER 1865
Query: 415 IRA----EVF-RKKLKEQREAELLTSAEKRAEMQKQIE-EMEKKLKEIQTTQQERTGDQQ 468
+R E F R++L+EQ E+ A+++K + E+E++ ++ T ++R +
Sbjct: 1866 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR-QVE 1924
Query: 469 EETMPTKETTKLQIASESQ 487
EE + K + + A +++
Sbjct: 1925 EEILALKASFEKAAAGKAE 1943
Score = 31.6 bits (70), Expect = 4.1
Identities = 28/114 (24%), Positives = 56/114 (49%), Gaps = 14/114 (12%)
Query: 379 LQRVQSHQQASEEKKEKMMYCKEKIYAGVGE----FSFEEIRAEVFRKKLK------EQR 428
LQ Q+ QQ+ +K+ ++ + I + F E +A+ R++ + EQ
Sbjct: 2485 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2544
Query: 429 EAELLTSAEKRAEMQKQIEE-MEKKLKEIQTTQQERTGDQQEETMPTKETTKLQ 481
L+ S E+ Q + EE + +K +E+Q +Q+R +Q+E + +E +L+
Sbjct: 2545 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR---RQQEELLAEENQRLR 2595
Score = 31.2 bits (69), Expect = 5.4
Identities = 66/342 (19%), Positives = 127/342 (37%), Gaps = 30/342 (8%)
Query: 163 EARENFRKADAIFQEGIQQKAE---PLERLQSQ-------HRQFQARVSRQTLLALEKEE 212
+ E A F++ KAE L R++S Q + +RQ LA E+E
Sbjct: 1922 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1981
Query: 213 EEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRI 272
E V + E ++ +K A + R+ ++ + R L+ Q+ ++
Sbjct: 1982 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQLQL 2038
Query: 273 TVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIA 332
A EA+ L A + KE ELQ L+ A+ A
Sbjct: 2039 ------AQEAAQKRLQAEEKAHAFA---VQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2089
Query: 333 VPAVLPSFTPYVEETAQ--QPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASE 390
+ E AQ + V +++ S R + + L R ++ Q+A+
Sbjct: 2090 AEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL-RKEAEQEAAR 2148
Query: 391 EKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEME 450
+ + ++K A ++ + R+K + ++E L + + QK + + E
Sbjct: 2149 RAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2208
Query: 451 KKLKEIQTTQQERTGDQQEETM-----PTKETTKLQIASESQ 487
+ + + T+ R Q EE + +E +KL+ E++
Sbjct: 2209 LQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2250
Score = 30.8 bits (68), Expect = 7.0
Identities = 25/157 (15%), Positives = 77/157 (49%), Gaps = 14/157 (8%)
Query: 334 PAVLPSFTPYVEETAQQPVMTPCKIEPSINHILS-TRKPGKEEGDPLQRVQSHQQASEEK 392
P P+ P V+ ++ + + + + + T + K + L+R++ ++ +E++
Sbjct: 1295 PVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQ 1354
Query: 393 KEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRA-EMQKQIEEMEK 451
+ + +E++ E+ A + +++ + A+ AE+ A E+Q++++E
Sbjct: 1355 RAEE---RERL---------AEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVV 1402
Query: 452 KLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQK 488
+ +E Q++ QEE +++++ +I +++++
Sbjct: 1403 RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQ 1439
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 40.8 bits (94), Expect = 0.007
Identities = 85/468 (18%), Positives = 172/468 (36%), Gaps = 34/468 (7%)
Query: 33 RQGRIMSTLQGALAQESACNNTLQQQKRAFEYEIRFYTGNDPLDVW---DRYISWTEQNY 89
R +++ Q LAQ L+Q R Y + DPL W R Q
Sbjct: 1148 RVAQLLERWQAVLAQTDVRQRELEQLGRQLRY---YRESADPLGAWLQDARRRQEQIQAM 1204
Query: 90 PQGGKESNMSTLL-------------ERAVEALQGEKRYYSDPRFLNLWLKLGRLCNEPL 136
P ++ L E+ E + K+Y + + L L + EP+
Sbjct: 1205 PLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPV 1264
Query: 137 DMYSYLHN-QGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQQKAEPLERLQSQHRQ 195
+ Q S+ Q Y+ Y F ++ E ERL Q R
Sbjct: 1265 ASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA 1324
Query: 196 FQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQN 255
+ + ALEK+ + + ++ E K ++ + R A+ A Q
Sbjct: 1325 EERERLAEVEAALEKQRQLAEAHAQAKAQAE-REAKELQQRMQEEVVRREEAAVDAQQQK 1383
Query: 256 RGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQ-AGPWN 314
R +Q QQ++ +S + A +A AE S+ ++ I + + E Q G
Sbjct: 1384 RSIQEEL-QQLRQSSEAEI-QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1441
Query: 315 TGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKE 374
++L R A V++ +Q+ ++ + + + + +E
Sbjct: 1442 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVEL---ASRVKAEAEAARE 1498
Query: 375 EGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLT 434
+ LQ ++ + +EE + ++ A V ++ E ++ + + +++ +
Sbjct: 1499 KQRALQALEELRLQAEEAERRLR------QAEVERARQVQVALETAQRSAEAELQSKRAS 1552
Query: 435 SAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQI 482
AEK A++++ ++E + +++ + ER QQ E +E + ++
Sbjct: 1553 FAEKTAQLERSLQEEHVAVAQLR-EEAERRAQQQAEAERAREEAEREL 1599
Score = 33.5 bits (75), Expect = 1.1
Identities = 68/334 (20%), Positives = 133/334 (39%), Gaps = 35/334 (10%)
Query: 176 QEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAE--LKSK 233
Q +Q++AE ++++ + +R ++ A E ++ E + Q+ LAE LK K
Sbjct: 2231 QRFLQEEAEKMKQVAEE-------AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2283
Query: 234 GKKTARAPIIRVGGALK------APSQNRGLQNPFPQQMQNNSRITVFDENADEA----- 282
+ A ++ L A Q R LQ Q Q + T + EA
Sbjct: 2284 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQ 2343
Query: 283 ----STAELSKPTVQPWIAPPMPRAKEN--ELQAGPWNTGRSLEHRPRGNTASLIAVPAV 336
+ AE K V ++ RA+E+ + G L HR T + +
Sbjct: 2344 LEMSAEAERLKLRVAE-MSRAQARAEEDAQRFRKQAEEIGEKL-HRTELATQEKVTLVQT 2401
Query: 337 LPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKM 396
L + A++ ++E + K + + + +Q VQ Q E + +
Sbjct: 2402 LEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQ 2461
Query: 397 MYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEI 456
+ EK E E+ +A KL++ + E+ + + R E Q+Q ++ME++ + +
Sbjct: 2462 SFLSEKDSLLQRERFIEQEKA-----KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRL 2516
Query: 457 QTTQQE--RTGDQQEETMPTKETTKLQIASESQK 488
+ +E R + EE + K+ Q+ + ++
Sbjct: 2517 VASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2550
Score = 32.3 bits (72), Expect = 2.4
Identities = 62/319 (19%), Positives = 128/319 (40%), Gaps = 31/319 (9%)
Query: 176 QEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGK 235
+E QQK+ + Q + + R+ + + E+ E + ++ LAE ++ +
Sbjct: 1617 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1676
Query: 236 KTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPW 295
A +IR+ + Q R L ++Q + EA A++
Sbjct: 1677 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV-------- 1728
Query: 296 IAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQ-QPVMT 354
RA+ L A + R+ E + S + A F EE A+ + +
Sbjct: 1729 ------RAEMEVLLA---SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE 1779
Query: 355 PCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEE 414
K + + + R+ + E +++ + +A+ K E + KEK E E
Sbjct: 1780 EAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK------EAENER 1833
Query: 415 IRA----EVF-RKKLKEQREAELLTSAEKRAEMQKQIE-EMEKKLKEIQTTQQERTGDQQ 468
+R E F R++L+EQ E+ A+++K + E+E++ ++ T ++R +
Sbjct: 1834 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR-QVE 1892
Query: 469 EETMPTKETTKLQIASESQ 487
EE + K + + A +++
Sbjct: 1893 EEILALKASFEKAAAGKAE 1911
Score = 31.6 bits (70), Expect = 4.1
Identities = 28/114 (24%), Positives = 56/114 (49%), Gaps = 14/114 (12%)
Query: 379 LQRVQSHQQASEEKKEKMMYCKEKIYAGVGE----FSFEEIRAEVFRKKLK------EQR 428
LQ Q+ QQ+ +K+ ++ + I + F E +A+ R++ + EQ
Sbjct: 2453 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2512
Query: 429 EAELLTSAEKRAEMQKQIEE-MEKKLKEIQTTQQERTGDQQEETMPTKETTKLQ 481
L+ S E+ Q + EE + +K +E+Q +Q+R +Q+E + +E +L+
Sbjct: 2513 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR---RQQEELLAEENQRLR 2563
Score = 31.2 bits (69), Expect = 5.4
Identities = 66/342 (19%), Positives = 127/342 (37%), Gaps = 30/342 (8%)
Query: 163 EARENFRKADAIFQEGIQQKAE---PLERLQSQ-------HRQFQARVSRQTLLALEKEE 212
+ E A F++ KAE L R++S Q + +RQ LA E+E
Sbjct: 1890 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1949
Query: 213 EEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRI 272
E V + E ++ +K A + R+ ++ + R L+ Q+ ++
Sbjct: 1950 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQLQL 2006
Query: 273 TVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIA 332
A EA+ L A + KE ELQ L+ A+ A
Sbjct: 2007 ------AQEAAQKRLQAEEKAHAFA---VQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2057
Query: 333 VPAVLPSFTPYVEETAQ--QPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASE 390
+ E AQ + V +++ S R + + L R ++ Q+A+
Sbjct: 2058 AEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL-RKEAEQEAAR 2116
Query: 391 EKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEME 450
+ + ++K A ++ + R+K + ++E L + + QK + + E
Sbjct: 2117 RAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2176
Query: 451 KKLKEIQTTQQERTGDQQEETM-----PTKETTKLQIASESQ 487
+ + + T+ R Q EE + +E +KL+ E++
Sbjct: 2177 LQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2218
Score = 30.8 bits (68), Expect = 7.0
Identities = 25/157 (15%), Positives = 77/157 (49%), Gaps = 14/157 (8%)
Query: 334 PAVLPSFTPYVEETAQQPVMTPCKIEPSINHILS-TRKPGKEEGDPLQRVQSHQQASEEK 392
P P+ P V+ ++ + + + + + T + K + L+R++ ++ +E++
Sbjct: 1263 PVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQ 1322
Query: 393 KEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRA-EMQKQIEEMEK 451
+ + +E++ E+ A + +++ + A+ AE+ A E+Q++++E
Sbjct: 1323 RAEE---RERL---------AEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVV 1370
Query: 452 KLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQK 488
+ +E Q++ QEE +++++ +I +++++
Sbjct: 1371 RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQ 1407
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 40.8 bits (94), Expect = 0.007
Identities = 85/468 (18%), Positives = 172/468 (36%), Gaps = 34/468 (7%)
Query: 33 RQGRIMSTLQGALAQESACNNTLQQQKRAFEYEIRFYTGNDPLDVW---DRYISWTEQNY 89
R +++ Q LAQ L+Q R Y + DPL W R Q
Sbjct: 1317 RVAQLLERWQAVLAQTDVRQRELEQLGRQLRY---YRESADPLGAWLQDARRRQEQIQAM 1373
Query: 90 PQGGKESNMSTLL-------------ERAVEALQGEKRYYSDPRFLNLWLKLGRLCNEPL 136
P ++ L E+ E + K+Y + + L L + EP+
Sbjct: 1374 PLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPV 1433
Query: 137 DMYSYLHN-QGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQQKAEPLERLQSQHRQ 195
+ Q S+ Q Y+ Y F ++ E ERL Q R
Sbjct: 1434 ASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA 1493
Query: 196 FQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQN 255
+ + ALEK+ + + ++ E K ++ + R A+ A Q
Sbjct: 1494 EERERLAEVEAALEKQRQLAEAHAQAKAQAE-REAKELQQRMQEEVVRREEAAVDAQQQK 1552
Query: 256 RGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQ-AGPWN 314
R +Q QQ++ +S + A +A AE S+ ++ I + + E Q G
Sbjct: 1553 RSIQEEL-QQLRQSSEAEI-QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1610
Query: 315 TGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKE 374
++L R A V++ +Q+ ++ + + + + +E
Sbjct: 1611 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVEL---ASRVKAEAEAARE 1667
Query: 375 EGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLT 434
+ LQ ++ + +EE + ++ A V ++ E ++ + + +++ +
Sbjct: 1668 KQRALQALEELRLQAEEAERRLR------QAEVERARQVQVALETAQRSAEAELQSKRAS 1721
Query: 435 SAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQI 482
AEK A++++ ++E + +++ + ER QQ E +E + ++
Sbjct: 1722 FAEKTAQLERSLQEEHVAVAQLR-EEAERRAQQQAEAERAREEAEREL 1768
Score = 33.5 bits (75), Expect = 1.1
Identities = 68/334 (20%), Positives = 133/334 (39%), Gaps = 35/334 (10%)
Query: 176 QEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAE--LKSK 233
Q +Q++AE ++++ + +R ++ A E ++ E + Q+ LAE LK K
Sbjct: 2400 QRFLQEEAEKMKQVAEE-------AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2452
Query: 234 GKKTARAPIIRVGGALK------APSQNRGLQNPFPQQMQNNSRITVFDENADEA----- 282
+ A ++ L A Q R LQ Q Q + T + EA
Sbjct: 2453 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQ 2512
Query: 283 ----STAELSKPTVQPWIAPPMPRAKEN--ELQAGPWNTGRSLEHRPRGNTASLIAVPAV 336
+ AE K V ++ RA+E+ + G L HR T + +
Sbjct: 2513 LEMSAEAERLKLRVAE-MSRAQARAEEDAQRFRKQAEEIGEKL-HRTELATQEKVTLVQT 2570
Query: 337 LPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKM 396
L + A++ ++E + K + + + +Q VQ Q E + +
Sbjct: 2571 LEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQ 2630
Query: 397 MYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEI 456
+ EK E E+ +A KL++ + E+ + + R E Q+Q ++ME++ + +
Sbjct: 2631 SFLSEKDSLLQRERFIEQEKA-----KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRL 2685
Query: 457 QTTQQE--RTGDQQEETMPTKETTKLQIASESQK 488
+ +E R + EE + K+ Q+ + ++
Sbjct: 2686 VASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2719
Score = 32.3 bits (72), Expect = 2.4
Identities = 62/319 (19%), Positives = 128/319 (40%), Gaps = 31/319 (9%)
Query: 176 QEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGK 235
+E QQK+ + Q + + R+ + + E+ E + ++ LAE ++ +
Sbjct: 1786 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1845
Query: 236 KTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPW 295
A +IR+ + Q R L ++Q + EA A++
Sbjct: 1846 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV-------- 1897
Query: 296 IAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQ-QPVMT 354
RA+ L A + R+ E + S + A F EE A+ + +
Sbjct: 1898 ------RAEMEVLLA---SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE 1948
Query: 355 PCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEE 414
K + + + R+ + E +++ + +A+ K E + KEK E E
Sbjct: 1949 EAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK------EAENER 2002
Query: 415 IRA----EVF-RKKLKEQREAELLTSAEKRAEMQKQIE-EMEKKLKEIQTTQQERTGDQQ 468
+R E F R++L+EQ E+ A+++K + E+E++ ++ T ++R +
Sbjct: 2003 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR-QVE 2061
Query: 469 EETMPTKETTKLQIASESQ 487
EE + K + + A +++
Sbjct: 2062 EEILALKASFEKAAAGKAE 2080
Score = 31.6 bits (70), Expect = 4.1
Identities = 28/114 (24%), Positives = 56/114 (49%), Gaps = 14/114 (12%)
Query: 379 LQRVQSHQQASEEKKEKMMYCKEKIYAGVGE----FSFEEIRAEVFRKKLK------EQR 428
LQ Q+ QQ+ +K+ ++ + I + F E +A+ R++ + EQ
Sbjct: 2622 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2681
Query: 429 EAELLTSAEKRAEMQKQIEE-MEKKLKEIQTTQQERTGDQQEETMPTKETTKLQ 481
L+ S E+ Q + EE + +K +E+Q +Q+R +Q+E + +E +L+
Sbjct: 2682 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR---RQQEELLAEENQRLR 2732
Score = 31.2 bits (69), Expect = 5.4
Identities = 66/342 (19%), Positives = 127/342 (37%), Gaps = 30/342 (8%)
Query: 163 EARENFRKADAIFQEGIQQKAE---PLERLQSQ-------HRQFQARVSRQTLLALEKEE 212
+ E A F++ KAE L R++S Q + +RQ LA E+E
Sbjct: 2059 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 2118
Query: 213 EEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRI 272
E V + E ++ +K A + R+ ++ + R L+ Q+ ++
Sbjct: 2119 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQLQL 2175
Query: 273 TVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIA 332
A EA+ L A + KE ELQ L+ A+ A
Sbjct: 2176 ------AQEAAQKRLQAEEKAHAFA---VQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2226
Query: 333 VPAVLPSFTPYVEETAQ--QPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASE 390
+ E AQ + V +++ S R + + L R ++ Q+A+
Sbjct: 2227 AEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL-RKEAEQEAAR 2285
Query: 391 EKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEME 450
+ + ++K A ++ + R+K + ++E L + + QK + + E
Sbjct: 2286 RAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2345
Query: 451 KKLKEIQTTQQERTGDQQEETM-----PTKETTKLQIASESQ 487
+ + + T+ R Q EE + +E +KL+ E++
Sbjct: 2346 LQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2387
Score = 30.8 bits (68), Expect = 7.0
Identities = 25/157 (15%), Positives = 77/157 (49%), Gaps = 14/157 (8%)
Query: 334 PAVLPSFTPYVEETAQQPVMTPCKIEPSINHILS-TRKPGKEEGDPLQRVQSHQQASEEK 392
P P+ P V+ ++ + + + + + T + K + L+R++ ++ +E++
Sbjct: 1432 PVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQ 1491
Query: 393 KEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRA-EMQKQIEEMEK 451
+ + +E++ E+ A + +++ + A+ AE+ A E+Q++++E
Sbjct: 1492 RAEE---RERL---------AEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVV 1539
Query: 452 KLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQK 488
+ +E Q++ QEE +++++ +I +++++
Sbjct: 1540 RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQ 1576
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 40.8 bits (94), Expect = 0.007
Identities = 85/468 (18%), Positives = 172/468 (36%), Gaps = 34/468 (7%)
Query: 33 RQGRIMSTLQGALAQESACNNTLQQQKRAFEYEIRFYTGNDPLDVW---DRYISWTEQNY 89
R +++ Q LAQ L+Q R Y + DPL W R Q
Sbjct: 1158 RVAQLLERWQAVLAQTDVRQRELEQLGRQLRY---YRESADPLGAWLQDARRRQEQIQAM 1214
Query: 90 PQGGKESNMSTLL-------------ERAVEALQGEKRYYSDPRFLNLWLKLGRLCNEPL 136
P ++ L E+ E + K+Y + + L L + EP+
Sbjct: 1215 PLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPV 1274
Query: 137 DMYSYLHN-QGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQQKAEPLERLQSQHRQ 195
+ Q S+ Q Y+ Y F ++ E ERL Q R
Sbjct: 1275 ASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA 1334
Query: 196 FQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQN 255
+ + ALEK+ + + ++ E K ++ + R A+ A Q
Sbjct: 1335 EERERLAEVEAALEKQRQLAEAHAQAKAQAE-REAKELQQRMQEEVVRREEAAVDAQQQK 1393
Query: 256 RGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQ-AGPWN 314
R +Q QQ++ +S + A +A AE S+ ++ I + + E Q G
Sbjct: 1394 RSIQEEL-QQLRQSSEAEI-QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1451
Query: 315 TGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKE 374
++L R A V++ +Q+ ++ + + + + +E
Sbjct: 1452 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVEL---ASRVKAEAEAARE 1508
Query: 375 EGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLT 434
+ LQ ++ + +EE + ++ A V ++ E ++ + + +++ +
Sbjct: 1509 KQRALQALEELRLQAEEAERRLR------QAEVERARQVQVALETAQRSAEAELQSKRAS 1562
Query: 435 SAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQI 482
AEK A++++ ++E + +++ + ER QQ E +E + ++
Sbjct: 1563 FAEKTAQLERSLQEEHVAVAQLR-EEAERRAQQQAEAERAREEAEREL 1609
Score = 33.5 bits (75), Expect = 1.1
Identities = 68/334 (20%), Positives = 133/334 (39%), Gaps = 35/334 (10%)
Query: 176 QEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAE--LKSK 233
Q +Q++AE ++++ + +R ++ A E ++ E + Q+ LAE LK K
Sbjct: 2241 QRFLQEEAEKMKQVAEE-------AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2293
Query: 234 GKKTARAPIIRVGGALK------APSQNRGLQNPFPQQMQNNSRITVFDENADEA----- 282
+ A ++ L A Q R LQ Q Q + T + EA
Sbjct: 2294 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQ 2353
Query: 283 ----STAELSKPTVQPWIAPPMPRAKEN--ELQAGPWNTGRSLEHRPRGNTASLIAVPAV 336
+ AE K V ++ RA+E+ + G L HR T + +
Sbjct: 2354 LEMSAEAERLKLRVAE-MSRAQARAEEDAQRFRKQAEEIGEKL-HRTELATQEKVTLVQT 2411
Query: 337 LPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKM 396
L + A++ ++E + K + + + +Q VQ Q E + +
Sbjct: 2412 LEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQ 2471
Query: 397 MYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEI 456
+ EK E E+ +A KL++ + E+ + + R E Q+Q ++ME++ + +
Sbjct: 2472 SFLSEKDSLLQRERFIEQEKA-----KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRL 2526
Query: 457 QTTQQE--RTGDQQEETMPTKETTKLQIASESQK 488
+ +E R + EE + K+ Q+ + ++
Sbjct: 2527 VASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2560
Score = 32.3 bits (72), Expect = 2.4
Identities = 62/319 (19%), Positives = 128/319 (40%), Gaps = 31/319 (9%)
Query: 176 QEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGK 235
+E QQK+ + Q + + R+ + + E+ E + ++ LAE ++ +
Sbjct: 1627 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1686
Query: 236 KTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPW 295
A +IR+ + Q R L ++Q + EA A++
Sbjct: 1687 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV-------- 1738
Query: 296 IAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQ-QPVMT 354
RA+ L A + R+ E + S + A F EE A+ + +
Sbjct: 1739 ------RAEMEVLLA---SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE 1789
Query: 355 PCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEE 414
K + + + R+ + E +++ + +A+ K E + KEK E E
Sbjct: 1790 EAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK------EAENER 1843
Query: 415 IRA----EVF-RKKLKEQREAELLTSAEKRAEMQKQIE-EMEKKLKEIQTTQQERTGDQQ 468
+R E F R++L+EQ E+ A+++K + E+E++ ++ T ++R +
Sbjct: 1844 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR-QVE 1902
Query: 469 EETMPTKETTKLQIASESQ 487
EE + K + + A +++
Sbjct: 1903 EEILALKASFEKAAAGKAE 1921
Score = 31.6 bits (70), Expect = 4.1
Identities = 28/114 (24%), Positives = 56/114 (49%), Gaps = 14/114 (12%)
Query: 379 LQRVQSHQQASEEKKEKMMYCKEKIYAGVGE----FSFEEIRAEVFRKKLK------EQR 428
LQ Q+ QQ+ +K+ ++ + I + F E +A+ R++ + EQ
Sbjct: 2463 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2522
Query: 429 EAELLTSAEKRAEMQKQIEE-MEKKLKEIQTTQQERTGDQQEETMPTKETTKLQ 481
L+ S E+ Q + EE + +K +E+Q +Q+R +Q+E + +E +L+
Sbjct: 2523 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR---RQQEELLAEENQRLR 2573
Score = 31.2 bits (69), Expect = 5.4
Identities = 66/342 (19%), Positives = 127/342 (37%), Gaps = 30/342 (8%)
Query: 163 EARENFRKADAIFQEGIQQKAE---PLERLQSQ-------HRQFQARVSRQTLLALEKEE 212
+ E A F++ KAE L R++S Q + +RQ LA E+E
Sbjct: 1900 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1959
Query: 213 EEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRI 272
E V + E ++ +K A + R+ ++ + R L+ Q+ ++
Sbjct: 1960 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQLQL 2016
Query: 273 TVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIA 332
A EA+ L A + KE ELQ L+ A+ A
Sbjct: 2017 ------AQEAAQKRLQAEEKAHAFA---VQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2067
Query: 333 VPAVLPSFTPYVEETAQ--QPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASE 390
+ E AQ + V +++ S R + + L R ++ Q+A+
Sbjct: 2068 AEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL-RKEAEQEAAR 2126
Query: 391 EKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEME 450
+ + ++K A ++ + R+K + ++E L + + QK + + E
Sbjct: 2127 RAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2186
Query: 451 KKLKEIQTTQQERTGDQQEETM-----PTKETTKLQIASESQ 487
+ + + T+ R Q EE + +E +KL+ E++
Sbjct: 2187 LQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2228
Score = 30.8 bits (68), Expect = 7.0
Identities = 25/157 (15%), Positives = 77/157 (49%), Gaps = 14/157 (8%)
Query: 334 PAVLPSFTPYVEETAQQPVMTPCKIEPSINHILS-TRKPGKEEGDPLQRVQSHQQASEEK 392
P P+ P V+ ++ + + + + + T + K + L+R++ ++ +E++
Sbjct: 1273 PVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQ 1332
Query: 393 KEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRA-EMQKQIEEMEK 451
+ + +E++ E+ A + +++ + A+ AE+ A E+Q++++E
Sbjct: 1333 RAEE---RERL---------AEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVV 1380
Query: 452 KLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQK 488
+ +E Q++ QEE +++++ +I +++++
Sbjct: 1381 RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQ 1417
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 40.8 bits (94), Expect = 0.007
Identities = 85/468 (18%), Positives = 172/468 (36%), Gaps = 34/468 (7%)
Query: 33 RQGRIMSTLQGALAQESACNNTLQQQKRAFEYEIRFYTGNDPLDVW---DRYISWTEQNY 89
R +++ Q LAQ L+Q R Y + DPL W R Q
Sbjct: 1166 RVAQLLERWQAVLAQTDVRQRELEQLGRQLRY---YRESADPLGAWLQDARRRQEQIQAM 1222
Query: 90 PQGGKESNMSTLL-------------ERAVEALQGEKRYYSDPRFLNLWLKLGRLCNEPL 136
P ++ L E+ E + K+Y + + L L + EP+
Sbjct: 1223 PLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPV 1282
Query: 137 DMYSYLHN-QGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQQKAEPLERLQSQHRQ 195
+ Q S+ Q Y+ Y F ++ E ERL Q R
Sbjct: 1283 ASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA 1342
Query: 196 FQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQN 255
+ + ALEK+ + + ++ E K ++ + R A+ A Q
Sbjct: 1343 EERERLAEVEAALEKQRQLAEAHAQAKAQAE-REAKELQQRMQEEVVRREEAAVDAQQQK 1401
Query: 256 RGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQ-AGPWN 314
R +Q QQ++ +S + A +A AE S+ ++ I + + E Q G
Sbjct: 1402 RSIQEEL-QQLRQSSEAEI-QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1459
Query: 315 TGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKE 374
++L R A V++ +Q+ ++ + + + + +E
Sbjct: 1460 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVEL---ASRVKAEAEAARE 1516
Query: 375 EGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLT 434
+ LQ ++ + +EE + ++ A V ++ E ++ + + +++ +
Sbjct: 1517 KQRALQALEELRLQAEEAERRLR------QAEVERARQVQVALETAQRSAEAELQSKRAS 1570
Query: 435 SAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQI 482
AEK A++++ ++E + +++ + ER QQ E +E + ++
Sbjct: 1571 FAEKTAQLERSLQEEHVAVAQLR-EEAERRAQQQAEAERAREEAEREL 1617
Score = 33.5 bits (75), Expect = 1.1
Identities = 68/334 (20%), Positives = 133/334 (39%), Gaps = 35/334 (10%)
Query: 176 QEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAE--LKSK 233
Q +Q++AE ++++ + +R ++ A E ++ E + Q+ LAE LK K
Sbjct: 2249 QRFLQEEAEKMKQVAEE-------AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2301
Query: 234 GKKTARAPIIRVGGALK------APSQNRGLQNPFPQQMQNNSRITVFDENADEA----- 282
+ A ++ L A Q R LQ Q Q + T + EA
Sbjct: 2302 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQ 2361
Query: 283 ----STAELSKPTVQPWIAPPMPRAKEN--ELQAGPWNTGRSLEHRPRGNTASLIAVPAV 336
+ AE K V ++ RA+E+ + G L HR T + +
Sbjct: 2362 LEMSAEAERLKLRVAE-MSRAQARAEEDAQRFRKQAEEIGEKL-HRTELATQEKVTLVQT 2419
Query: 337 LPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKM 396
L + A++ ++E + K + + + +Q VQ Q E + +
Sbjct: 2420 LEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQ 2479
Query: 397 MYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEI 456
+ EK E E+ +A KL++ + E+ + + R E Q+Q ++ME++ + +
Sbjct: 2480 SFLSEKDSLLQRERFIEQEKA-----KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRL 2534
Query: 457 QTTQQE--RTGDQQEETMPTKETTKLQIASESQK 488
+ +E R + EE + K+ Q+ + ++
Sbjct: 2535 VASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2568
Score = 32.3 bits (72), Expect = 2.4
Identities = 62/319 (19%), Positives = 128/319 (40%), Gaps = 31/319 (9%)
Query: 176 QEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGK 235
+E QQK+ + Q + + R+ + + E+ E + ++ LAE ++ +
Sbjct: 1635 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1694
Query: 236 KTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPW 295
A +IR+ + Q R L ++Q + EA A++
Sbjct: 1695 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV-------- 1746
Query: 296 IAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQ-QPVMT 354
RA+ L A + R+ E + S + A F EE A+ + +
Sbjct: 1747 ------RAEMEVLLA---SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE 1797
Query: 355 PCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEE 414
K + + + R+ + E +++ + +A+ K E + KEK E E
Sbjct: 1798 EAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK------EAENER 1851
Query: 415 IRA----EVF-RKKLKEQREAELLTSAEKRAEMQKQIE-EMEKKLKEIQTTQQERTGDQQ 468
+R E F R++L+EQ E+ A+++K + E+E++ ++ T ++R +
Sbjct: 1852 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR-QVE 1910
Query: 469 EETMPTKETTKLQIASESQ 487
EE + K + + A +++
Sbjct: 1911 EEILALKASFEKAAAGKAE 1929
Score = 31.6 bits (70), Expect = 4.1
Identities = 28/114 (24%), Positives = 56/114 (49%), Gaps = 14/114 (12%)
Query: 379 LQRVQSHQQASEEKKEKMMYCKEKIYAGVGE----FSFEEIRAEVFRKKLK------EQR 428
LQ Q+ QQ+ +K+ ++ + I + F E +A+ R++ + EQ
Sbjct: 2471 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2530
Query: 429 EAELLTSAEKRAEMQKQIEE-MEKKLKEIQTTQQERTGDQQEETMPTKETTKLQ 481
L+ S E+ Q + EE + +K +E+Q +Q+R +Q+E + +E +L+
Sbjct: 2531 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR---RQQEELLAEENQRLR 2581
Score = 31.2 bits (69), Expect = 5.4
Identities = 66/342 (19%), Positives = 127/342 (37%), Gaps = 30/342 (8%)
Query: 163 EARENFRKADAIFQEGIQQKAE---PLERLQSQ-------HRQFQARVSRQTLLALEKEE 212
+ E A F++ KAE L R++S Q + +RQ LA E+E
Sbjct: 1908 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1967
Query: 213 EEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRI 272
E V + E ++ +K A + R+ ++ + R L+ Q+ ++
Sbjct: 1968 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQLQL 2024
Query: 273 TVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIA 332
A EA+ L A + KE ELQ L+ A+ A
Sbjct: 2025 ------AQEAAQKRLQAEEKAHAFA---VQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2075
Query: 333 VPAVLPSFTPYVEETAQ--QPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASE 390
+ E AQ + V +++ S R + + L R ++ Q+A+
Sbjct: 2076 AEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL-RKEAEQEAAR 2134
Query: 391 EKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEME 450
+ + ++K A ++ + R+K + ++E L + + QK + + E
Sbjct: 2135 RAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2194
Query: 451 KKLKEIQTTQQERTGDQQEETM-----PTKETTKLQIASESQ 487
+ + + T+ R Q EE + +E +KL+ E++
Sbjct: 2195 LQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2236
Score = 30.8 bits (68), Expect = 7.0
Identities = 25/157 (15%), Positives = 77/157 (49%), Gaps = 14/157 (8%)
Query: 334 PAVLPSFTPYVEETAQQPVMTPCKIEPSINHILS-TRKPGKEEGDPLQRVQSHQQASEEK 392
P P+ P V+ ++ + + + + + T + K + L+R++ ++ +E++
Sbjct: 1281 PVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQ 1340
Query: 393 KEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRA-EMQKQIEEMEK 451
+ + +E++ E+ A + +++ + A+ AE+ A E+Q++++E
Sbjct: 1341 RAEE---RERL---------AEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVV 1388
Query: 452 KLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQK 488
+ +E Q++ QEE +++++ +I +++++
Sbjct: 1389 RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQ 1425
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 40.8 bits (94), Expect = 0.007
Identities = 85/468 (18%), Positives = 172/468 (36%), Gaps = 34/468 (7%)
Query: 33 RQGRIMSTLQGALAQESACNNTLQQQKRAFEYEIRFYTGNDPLDVW---DRYISWTEQNY 89
R +++ Q LAQ L+Q R Y + DPL W R Q
Sbjct: 1207 RVAQLLERWQAVLAQTDVRQRELEQLGRQLRY---YRESADPLGAWLQDARRRQEQIQAM 1263
Query: 90 PQGGKESNMSTLL-------------ERAVEALQGEKRYYSDPRFLNLWLKLGRLCNEPL 136
P ++ L E+ E + K+Y + + L L + EP+
Sbjct: 1264 PLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPV 1323
Query: 137 DMYSYLHN-QGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQQKAEPLERLQSQHRQ 195
+ Q S+ Q Y+ Y F ++ E ERL Q R
Sbjct: 1324 ASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA 1383
Query: 196 FQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQN 255
+ + ALEK+ + + ++ E K ++ + R A+ A Q
Sbjct: 1384 EERERLAEVEAALEKQRQLAEAHAQAKAQAE-REAKELQQRMQEEVVRREEAAVDAQQQK 1442
Query: 256 RGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQ-AGPWN 314
R +Q QQ++ +S + A +A AE S+ ++ I + + E Q G
Sbjct: 1443 RSIQEEL-QQLRQSSEAEI-QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1500
Query: 315 TGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKE 374
++L R A V++ +Q+ ++ + + + + +E
Sbjct: 1501 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVEL---ASRVKAEAEAARE 1557
Query: 375 EGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLT 434
+ LQ ++ + +EE + ++ A V ++ E ++ + + +++ +
Sbjct: 1558 KQRALQALEELRLQAEEAERRLR------QAEVERARQVQVALETAQRSAEAELQSKRAS 1611
Query: 435 SAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKLQI 482
AEK A++++ ++E + +++ + ER QQ E +E + ++
Sbjct: 1612 FAEKTAQLERSLQEEHVAVAQLR-EEAERRAQQQAEAERAREEAEREL 1658
Score = 33.5 bits (75), Expect = 1.1
Identities = 68/334 (20%), Positives = 133/334 (39%), Gaps = 35/334 (10%)
Query: 176 QEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAE--LKSK 233
Q +Q++AE ++++ + +R ++ A E ++ E + Q+ LAE LK K
Sbjct: 2290 QRFLQEEAEKMKQVAEE-------AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2342
Query: 234 GKKTARAPIIRVGGALK------APSQNRGLQNPFPQQMQNNSRITVFDENADEA----- 282
+ A ++ L A Q R LQ Q Q + T + EA
Sbjct: 2343 MQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQ 2402
Query: 283 ----STAELSKPTVQPWIAPPMPRAKEN--ELQAGPWNTGRSLEHRPRGNTASLIAVPAV 336
+ AE K V ++ RA+E+ + G L HR T + +
Sbjct: 2403 LEMSAEAERLKLRVAE-MSRAQARAEEDAQRFRKQAEEIGEKL-HRTELATQEKVTLVQT 2460
Query: 337 LPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKM 396
L + A++ ++E + K + + + +Q VQ Q E + +
Sbjct: 2461 LEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQ 2520
Query: 397 MYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEI 456
+ EK E E+ +A KL++ + E+ + + R E Q+Q ++ME++ + +
Sbjct: 2521 SFLSEKDSLLQRERFIEQEKA-----KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRL 2575
Query: 457 QTTQQE--RTGDQQEETMPTKETTKLQIASESQK 488
+ +E R + EE + K+ Q+ + ++
Sbjct: 2576 VASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2609
Score = 32.3 bits (72), Expect = 2.4
Identities = 62/319 (19%), Positives = 128/319 (40%), Gaps = 31/319 (9%)
Query: 176 QEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGK 235
+E QQK+ + Q + + R+ + + E+ E + ++ LAE ++ +
Sbjct: 1676 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1735
Query: 236 KTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPW 295
A +IR+ + Q R L ++Q + EA A++
Sbjct: 1736 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKV-------- 1787
Query: 296 IAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQ-QPVMT 354
RA+ L A + R+ E + S + A F EE A+ + +
Sbjct: 1788 ------RAEMEVLLA---SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE 1838
Query: 355 PCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEE 414
K + + + R+ + E +++ + +A+ K E + KEK E E
Sbjct: 1839 EAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK------EAENER 1892
Query: 415 IRA----EVF-RKKLKEQREAELLTSAEKRAEMQKQIE-EMEKKLKEIQTTQQERTGDQQ 468
+R E F R++L+EQ E+ A+++K + E+E++ ++ T ++R +
Sbjct: 1893 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR-QVE 1951
Query: 469 EETMPTKETTKLQIASESQ 487
EE + K + + A +++
Sbjct: 1952 EEILALKASFEKAAAGKAE 1970
Score = 31.6 bits (70), Expect = 4.1
Identities = 28/114 (24%), Positives = 56/114 (49%), Gaps = 14/114 (12%)
Query: 379 LQRVQSHQQASEEKKEKMMYCKEKIYAGVGE----FSFEEIRAEVFRKKLK------EQR 428
LQ Q+ QQ+ +K+ ++ + I + F E +A+ R++ + EQ
Sbjct: 2512 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2571
Query: 429 EAELLTSAEKRAEMQKQIEE-MEKKLKEIQTTQQERTGDQQEETMPTKETTKLQ 481
L+ S E+ Q + EE + +K +E+Q +Q+R +Q+E + +E +L+
Sbjct: 2572 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR---RQQEELLAEENQRLR 2622
Score = 31.2 bits (69), Expect = 5.4
Identities = 66/342 (19%), Positives = 127/342 (37%), Gaps = 30/342 (8%)
Query: 163 EARENFRKADAIFQEGIQQKAE---PLERLQSQ-------HRQFQARVSRQTLLALEKEE 212
+ E A F++ KAE L R++S Q + +RQ LA E+E
Sbjct: 1949 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 2008
Query: 213 EEEVFESSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRI 272
E V + E ++ +K A + R+ ++ + R L+ Q+ ++
Sbjct: 2009 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVE---EARRLRERAEQESARQLQL 2065
Query: 273 TVFDENADEASTAELSKPTVQPWIAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIA 332
A EA+ L A + KE ELQ L+ A+ A
Sbjct: 2066 ------AQEAAQKRLQAEEKAHAFA---VQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2116
Query: 333 VPAVLPSFTPYVEETAQ--QPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASE 390
+ E AQ + V +++ S R + + L R ++ Q+A+
Sbjct: 2117 AEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL-RKEAEQEAAR 2175
Query: 391 EKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEME 450
+ + ++K A ++ + R+K + ++E L + + QK + + E
Sbjct: 2176 RAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEE 2235
Query: 451 KKLKEIQTTQQERTGDQQEETM-----PTKETTKLQIASESQ 487
+ + + T+ R Q EE + +E +KL+ E++
Sbjct: 2236 LQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2277
Score = 30.8 bits (68), Expect = 7.0
Identities = 25/157 (15%), Positives = 77/157 (49%), Gaps = 14/157 (8%)
Query: 334 PAVLPSFTPYVEETAQQPVMTPCKIEPSINHILS-TRKPGKEEGDPLQRVQSHQQASEEK 392
P P+ P V+ ++ + + + + + T + K + L+R++ ++ +E++
Sbjct: 1322 PVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQ 1381
Query: 393 KEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRA-EMQKQIEEMEK 451
+ + +E++ E+ A + +++ + A+ AE+ A E+Q++++E
Sbjct: 1382 RAEE---RERL---------AEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVV 1429
Query: 452 KLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQK 488
+ +E Q++ QEE +++++ +I +++++
Sbjct: 1430 RREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQ 1466
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,088,263
Number of Sequences: 37866
Number of extensions: 1947971
Number of successful extensions: 12905
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 116
Number of HSP's successfully gapped in prelim test: 464
Number of HSP's that attempted gapping in prelim test: 9727
Number of HSP's gapped (non-prelim): 2787
length of query: 1050
length of database: 18,247,518
effective HSP length: 113
effective length of query: 937
effective length of database: 13,968,660
effective search space: 13088634420
effective search space used: 13088634420
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.