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Search of human proteins with 58761548
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58761548 tau tubulin kinase 1 [Homo sapiens]
(1321 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 2626 0.0
gi|116812624 tau tubulin kinase 2 [Homo sapiens] 662 0.0
gi|20544145 casein kinase 1, delta isoform 2 [Homo sapiens] 180 9e-45
gi|20149530 casein kinase 1, delta isoform 1 [Homo sapiens] 180 9e-45
gi|23199991 casein kinase 1 epsilon [Homo sapiens] 176 1e-43
gi|4503093 casein kinase 1 epsilon [Homo sapiens] 176 1e-43
gi|68303572 casein kinase 1, alpha 1 isoform 2 [Homo sapiens] 172 2e-42
gi|98986450 casein kinase 1, gamma 1 [Homo sapiens] 163 9e-40
gi|68303575 casein kinase 1, alpha 1 isoform 1 [Homo sapiens] 161 4e-39
gi|21624639 casein kinase 1, alpha 1-like [Homo sapiens] 161 4e-39
gi|153791733 casein kinase 1, gamma 2 [Homo sapiens] 160 6e-39
gi|113462010 casein kinase 1, gamma 3 isoform 4 [Homo sapiens] 154 4e-37
gi|113462008 casein kinase 1, gamma 3 isoform 3 [Homo sapiens] 154 4e-37
gi|73532780 casein kinase 1, gamma 3 isoform 2 [Homo sapiens] 154 4e-37
gi|73532778 casein kinase 1, gamma 3 isoform 1 [Homo sapiens] 154 4e-37
gi|194440713 vaccinia related kinase 2 isoform 3 [Homo sapiens] 100 7e-21
gi|194440711 vaccinia related kinase 2 isoform 2 [Homo sapiens] 100 7e-21
gi|194440709 vaccinia related kinase 2 isoform 1 [Homo sapiens] 100 7e-21
gi|194440707 vaccinia related kinase 2 isoform 1 [Homo sapiens] 100 7e-21
gi|71164884 vaccinia related kinase 2 isoform 1 [Homo sapiens] 100 7e-21
gi|4507903 vaccinia related kinase 1 [Homo sapiens] 95 5e-19
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a... 87 1e-16
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b... 87 1e-16
gi|15011880 serine/threonine protein kinase MST4 isoform 1 [Homo... 86 2e-16
gi|209862855 vaccinia related kinase 2 isoform 6 [Homo sapiens] 83 2e-15
gi|17975763 myelin transcription factor 1 [Homo sapiens] 82 3e-15
gi|110349738 serine/threonine kinase 24 isoform b [Homo sapiens] 79 3e-14
gi|20070158 serine/threonine kinase 24 isoform a [Homo sapiens] 79 3e-14
gi|21361358 serine/threonine kinase 25 [Homo sapiens] 78 5e-14
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 78 6e-14
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 2626 bits (6807), Expect = 0.0
Identities = 1321/1321 (100%), Positives = 1321/1321 (100%)
Query: 1 MQCLAAALKDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENV 60
MQCLAAALKDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENV
Sbjct: 1 MQCLAAALKDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENV 60
Query: 61 ALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRS 120
ALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRS
Sbjct: 61 ALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRS 120
Query: 121 QPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLA 180
QPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLA
Sbjct: 121 QPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLA 180
Query: 181 RQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWR 240
RQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWR
Sbjct: 181 RQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWR 240
Query: 241 KIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKER 300
KIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKER
Sbjct: 241 KIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKER 300
Query: 301 GIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQ 360
GIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQ
Sbjct: 301 GIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQ 360
Query: 361 GEHLSDQENAPPILPGRPSEGLGPSPHLVPHPGGPEAEVWEETDVNRNKLRINIGKSPCV 420
GEHLSDQENAPPILPGRPSEGLGPSPHLVPHPGGPEAEVWEETDVNRNKLRINIGKSPCV
Sbjct: 361 GEHLSDQENAPPILPGRPSEGLGPSPHLVPHPGGPEAEVWEETDVNRNKLRINIGKSPCV 420
Query: 421 EEEQSRGMGVPSSPVRAPPDSPTTPVRSLRYRRVNSPESERLSTADGRVELPERRSRMDL 480
EEEQSRGMGVPSSPVRAPPDSPTTPVRSLRYRRVNSPESERLSTADGRVELPERRSRMDL
Sbjct: 421 EEEQSRGMGVPSSPVRAPPDSPTTPVRSLRYRRVNSPESERLSTADGRVELPERRSRMDL 480
Query: 481 PGSPSRQACSSQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFRSVPLAEEEDFDS 540
PGSPSRQACSSQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFRSVPLAEEEDFDS
Sbjct: 481 PGSPSRQACSSQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFRSVPLAEEEDFDS 540
Query: 541 KEWVIIDKETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLGAEPTVRPRGRSM 600
KEWVIIDKETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLGAEPTVRPRGRSM
Sbjct: 541 KEWVIIDKETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLGAEPTVRPRGRSM 600
Query: 601 QALAEEDLQHLPPQPLPPQLSQGDGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQ 660
QALAEEDLQHLPPQPLPPQLSQGDGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQ
Sbjct: 601 QALAEEDLQHLPPQPLPPQLSQGDGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQ 660
Query: 661 RQVFSVAPPFEVNGLPRAVPLSLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQV 720
RQVFSVAPPFEVNGLPRAVPLSLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQV
Sbjct: 661 RQVFSVAPPFEVNGLPRAVPLSLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQV 720
Query: 721 PLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGE 780
PLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGE
Sbjct: 721 PLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGE 780
Query: 781 VLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVS 840
VLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVS
Sbjct: 781 VLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVS 840
Query: 841 PGDMKKSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPKPPGP 900
PGDMKKSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPKPPGP
Sbjct: 841 PGDMKKSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPKPPGP 900
Query: 901 GAGLGAGTVTTGVGGVAVTSSPFTKVERTFVHIAEKTHLNVMSSGGQALRSEEFSAGGEL 960
GAGLGAGTVTTGVGGVAVTSSPFTKVERTFVHIAEKTHLNVMSSGGQALRSEEFSAGGEL
Sbjct: 901 GAGLGAGTVTTGVGGVAVTSSPFTKVERTFVHIAEKTHLNVMSSGGQALRSEEFSAGGEL 960
Query: 961 GLELASDGGAVEEGARAPLENGLALSGLNGAEIEGSALSGAPRETPSEMATNSLPNGPAL 1020
GLELASDGGAVEEGARAPLENGLALSGLNGAEIEGSALSGAPRETPSEMATNSLPNGPAL
Sbjct: 961 GLELASDGGAVEEGARAPLENGLALSGLNGAEIEGSALSGAPRETPSEMATNSLPNGPAL 1020
Query: 1021 ADGPAPVSPLEPSPEKVATISPRRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWS 1080
ADGPAPVSPLEPSPEKVATISPRRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWS
Sbjct: 1021 ADGPAPVSPLEPSPEKVATISPRRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWS 1080
Query: 1081 KRARPQQDLARLVMEKRQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAA 1140
KRARPQQDLARLVMEKRQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAA
Sbjct: 1081 KRARPQQDLARLVMEKRQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAA 1140
Query: 1141 ALPRKSGRAAATRSRIPRPIGLRMPMPVAAQQPASRSHGAAPALDTAITSRLQLQTPPGS 1200
ALPRKSGRAAATRSRIPRPIGLRMPMPVAAQQPASRSHGAAPALDTAITSRLQLQTPPGS
Sbjct: 1141 ALPRKSGRAAATRSRIPRPIGLRMPMPVAAQQPASRSHGAAPALDTAITSRLQLQTPPGS 1200
Query: 1201 ATAADLRPKQPPGRGLGPGRAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRRESP 1260
ATAADLRPKQPPGRGLGPGRAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRRESP
Sbjct: 1201 ATAADLRPKQPPGRGLGPGRAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRRESP 1260
Query: 1261 SPSHQARPGVPPPRGVPPARAQPDGTPSPGGSKKGPRGKLQAQRATTKGRAGGAEGRAGA 1320
SPSHQARPGVPPPRGVPPARAQPDGTPSPGGSKKGPRGKLQAQRATTKGRAGGAEGRAGA
Sbjct: 1261 SPSHQARPGVPPPRGVPPARAQPDGTPSPGGSKKGPRGKLQAQRATTKGRAGGAEGRAGA 1320
Query: 1321 R 1321
R
Sbjct: 1321 R 1321
>gi|116812624 tau tubulin kinase 2 [Homo sapiens]
Length = 1244
Score = 662 bits (1709), Expect = 0.0
Identities = 383/716 (53%), Positives = 470/716 (65%), Gaps = 74/716 (10%)
Query: 14 MSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQV 73
MSGGGEQ DIL +VK+RWKVL+KIGGGGFGEIY+A+D+LTRENVALKVESAQQPKQV
Sbjct: 1 MSGGGEQLDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQV 60
Query: 74 LKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLR 133
LKMEVAVLKKLQGKDHVCRFIGCGRN++FNYVVMQLQGRNLADLRRSQ RGTFT+STTLR
Sbjct: 61 LKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLR 120
Query: 134 LGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPP 193
LG+QILESIE+IHSVGFLHRDIKPSNFAMGR PST RKCYMLDFGLARQ+TN+ GDVRPP
Sbjct: 121 LGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVRPP 180
Query: 194 RNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKE 253
R VAGFRGTVRYAS+NAH+NREMGRHDDLWSLFYMLVEF VGQLPWRKIKDKEQVG IKE
Sbjct: 181 RAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKE 240
Query: 254 KYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKA 313
+Y+HR++LKH+P EF +FLDHI+SLDYFTKPDYQL+ SVF+NS+K G+ E++ FDWEK
Sbjct: 241 RYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWEKT 300
Query: 314 GTD-ALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPP 372
G D +L +T+TST PQ +TR T A G+ N TP+PGDLLRENT++V E LSD EN P
Sbjct: 301 GNDGSLTTTTTSTTPQLHTRLTPAAIGIANATPIPGDLLRENTDEVFPDEQLSDGENGIP 360
Query: 373 ILPGRPSEGLGPS--PHLVPHPGGPEAEVWEETDVNRNKLRINIGKSPCVEEEQSRG--- 427
+ G+ P P + HP E +VWEE D N+NK+++ I K+ EEE S G
Sbjct: 361 V-------GVSPDKLPGSLGHPRPQEKDVWEEMDANKNKIKLGICKA-ATEEENSHGQAN 412
Query: 428 --MGVPS--SPVR-----APPDSPTTPVRSLRYRRVNSPESERLSTADGRVE----LPER 474
+ PS SP+R PD VR L R ++S E E+ T + + + L
Sbjct: 413 GLLNAPSLGSPIRVRSEITQPDRDIPLVRKL--RSIHSFELEKRLTLEPKPDTDKFLETC 470
Query: 475 RSRMDLPGSPSRQAC-------SSQPAQMLSVDTGHADRQ--ASGRMDVSASVEQEA--- 522
+M S +++ PA + H D + SA+ ++A
Sbjct: 471 LEKMQKDTSAGKESILPALLHKPCVPAVSRTDHIWHYDEEYLPDASKPASANTPEQADGG 530
Query: 523 LSNAFRSVPLAE-EEDFDSKEWVIIDKETELKDFPPG---AEPSTSGTTDEEPEELRPL- 577
SN F +V L+ +++ DSKEWVI+DKE +L+DF +T +DEEPE L+ L
Sbjct: 531 GSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPSDEEPEVLQVLE 590
Query: 578 PEEGEERRRLG--AEPTVRPRGRSMQALA-----------EEDLQHLPPQP--------- 615
+E+ +LG AE + S LA E+ L QP
Sbjct: 591 ASPQDEKLQLGPWAENDHLKKETSGVVLALSAEGPPTAASEQYTDRLELQPGAASQFIAA 650
Query: 616 LPPQL--SQGDGRSETSQPPTPGSPS----HSPLHSGPRPRRRESDPTGPQRQVFS 665
P L +Q +G P P S H G +P +++ P P +++S
Sbjct: 651 TPTSLMEAQAEGPLTAITIPRPSVASTQSTSGSFHCGQQPEKKDLQPMEPTVELYS 706
Score = 73.9 bits (180), Expect = 9e-13
Identities = 82/281 (29%), Positives = 117/281 (41%), Gaps = 24/281 (8%)
Query: 1054 SRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLVMEKRQGRLLLRLASGASSSS 1113
SRIPVL E D+ E S +SAKE+ ++ Q DL +L++EKRQ + L S AS
Sbjct: 943 SRIPVLAQEIDSTLESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKL 1002
Query: 1114 SEEQRRASETLSGTGSEEDTPASEPAAALPRKSGRAA-----------ATRSRIPRPIGL 1162
EE+ T+ EE+ + R+A + +S+IPRP+
Sbjct: 1003 LEEK---LATVPAPFCEEEVLTPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSW 1059
Query: 1163 RMPMPV---AAQQPASRSHGAAPALDTAITSRLQLQTPPGSATA-ADL--RPKQPPGRGL 1216
V + Q R P + +RL+ GS+ + +DL R Q G
Sbjct: 1060 VNTDQVNSSTSSQFFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGS 1119
Query: 1217 GPGRAQAGARPP-APRSPRLPASTSAA--RNASASPRSQSLSRRESPSPSHQARPGVPPP 1273
R+ + P +P +P+ P + R+ SASPRS SL R S SPS RP
Sbjct: 1120 QKPRSTTQCKSPGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPH-HDQ 1178
Query: 1274 RGVPPARAQPDGTPSPGGSKKGPRGKLQAQRATTKGRAGGA 1314
R P + PS GS R Q +K G+
Sbjct: 1179 RSSSPHLGRSKSPPSHSGSSSSRRSCQQEHCKPSKNGLKGS 1219
>gi|20544145 casein kinase 1, delta isoform 2 [Homo sapiens]
Length = 409
Score = 180 bits (456), Expect = 9e-45
Identities = 109/292 (37%), Positives = 155/292 (53%), Gaps = 17/292 (5%)
Query: 30 VKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDH 89
V +R+++ +KIG G FG+IY D+ E VA+K+E + L +E + K +QG
Sbjct: 5 VGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVG 64
Query: 90 VCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVG 149
+ CG +N +VM+L G +L DL R F+L T L L Q++ IE IHS
Sbjct: 65 IPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSR-KFSLKTVLLLADQMISRIEYIHSKN 123
Query: 150 FLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNT-TGDVRPPRNVAGFRGTVRYASV 208
F+HRD+KP NF MG L Y++DFGLA++Y + T P R GT RYAS+
Sbjct: 124 FIHRDVKPDNFLMG-LGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASI 182
Query: 209 NAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEH----------R 258
N H E R DDL SL Y+L+ F +G LPW+ +K + ++KYE
Sbjct: 183 NTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATK----RQKYERISEKKMSTPIE 238
Query: 259 MLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDW 310
+L K PSEF +L+ SL + KPDY + +F N +G + + FDW
Sbjct: 239 VLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW 290
>gi|20149530 casein kinase 1, delta isoform 1 [Homo sapiens]
Length = 415
Score = 180 bits (456), Expect = 9e-45
Identities = 109/292 (37%), Positives = 155/292 (53%), Gaps = 17/292 (5%)
Query: 30 VKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDH 89
V +R+++ +KIG G FG+IY D+ E VA+K+E + L +E + K +QG
Sbjct: 5 VGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVG 64
Query: 90 VCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVG 149
+ CG +N +VM+L G +L DL R F+L T L L Q++ IE IHS
Sbjct: 65 IPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSR-KFSLKTVLLLADQMISRIEYIHSKN 123
Query: 150 FLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNT-TGDVRPPRNVAGFRGTVRYASV 208
F+HRD+KP NF MG L Y++DFGLA++Y + T P R GT RYAS+
Sbjct: 124 FIHRDVKPDNFLMG-LGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASI 182
Query: 209 NAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEH----------R 258
N H E R DDL SL Y+L+ F +G LPW+ +K + ++KYE
Sbjct: 183 NTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATK----RQKYERISEKKMSTPIE 238
Query: 259 MLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDW 310
+L K PSEF +L+ SL + KPDY + +F N +G + + FDW
Sbjct: 239 VLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW 290
>gi|23199991 casein kinase 1 epsilon [Homo sapiens]
Length = 416
Score = 176 bits (447), Expect = 1e-43
Identities = 144/485 (29%), Positives = 204/485 (42%), Gaps = 87/485 (17%)
Query: 30 VKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDH 89
V +++++ +KIG G FG+IY ++ + E VA+K+E + L +E K +QG
Sbjct: 5 VGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVG 64
Query: 90 VCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVG 149
+ CG +N +VM+L G +L DL R F+L T L L Q++ IE IHS
Sbjct: 65 IPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSR-KFSLKTVLLLADQMISRIEYIHSKN 123
Query: 150 FLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNT-TGDVRPPRNVAGFRGTVRYASV 208
F+HRD+KP NF MG L Y++DFGLA++Y + T P R GT RYAS+
Sbjct: 124 FIHRDVKPDNFLMG-LGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASI 182
Query: 209 NAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEH----------R 258
N H E R DDL SL Y+L+ F +G LPW+ +K + ++KYE
Sbjct: 183 NTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATK----RQKYERISEKKMSTPIE 238
Query: 259 MLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDAL 318
+L K PSEF +L+ SL + KPDY + +F N +G + + FDW
Sbjct: 239 VLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW-------- 290
Query: 319 LSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPILPGRP 378
FG N EDV + ++E L G
Sbjct: 291 ---------------NMLKFGAA-----------RNPEDVDRERREHEREERMGQLRGSA 324
Query: 379 SEGLGPSPHLVPHPGGPEAEVWEETDVNRNKLRINIGKSPCVEEEQSRGMGVPSSPVRAP 438
+ L P P T N+LR + PV +
Sbjct: 325 TRALPPGP---------------PTGATANRLR------------------SAAEPVAST 351
Query: 439 PDSPTTPVRSLRYRRVNSPESERLSTADGRVELPERRSRMDLPGSPSRQACSSQPAQMLS 498
P S P + R ++ + ER + P S DL G RQ S PA S
Sbjct: 352 PASRIQPAGNTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTG---RQEVSRIPASQTS 408
Query: 499 VDTGH 503
V H
Sbjct: 409 VPFDH 413
>gi|4503093 casein kinase 1 epsilon [Homo sapiens]
Length = 416
Score = 176 bits (447), Expect = 1e-43
Identities = 144/485 (29%), Positives = 204/485 (42%), Gaps = 87/485 (17%)
Query: 30 VKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDH 89
V +++++ +KIG G FG+IY ++ + E VA+K+E + L +E K +QG
Sbjct: 5 VGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVG 64
Query: 90 VCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVG 149
+ CG +N +VM+L G +L DL R F+L T L L Q++ IE IHS
Sbjct: 65 IPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSR-KFSLKTVLLLADQMISRIEYIHSKN 123
Query: 150 FLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNT-TGDVRPPRNVAGFRGTVRYASV 208
F+HRD+KP NF MG L Y++DFGLA++Y + T P R GT RYAS+
Sbjct: 124 FIHRDVKPDNFLMG-LGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASI 182
Query: 209 NAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEH----------R 258
N H E R DDL SL Y+L+ F +G LPW+ +K + ++KYE
Sbjct: 183 NTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATK----RQKYERISEKKMSTPIE 238
Query: 259 MLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDAL 318
+L K PSEF +L+ SL + KPDY + +F N +G + + FDW
Sbjct: 239 VLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW-------- 290
Query: 319 LSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPILPGRP 378
FG N EDV + ++E L G
Sbjct: 291 ---------------NMLKFGAA-----------RNPEDVDRERREHEREERMGQLRGSA 324
Query: 379 SEGLGPSPHLVPHPGGPEAEVWEETDVNRNKLRINIGKSPCVEEEQSRGMGVPSSPVRAP 438
+ L P P T N+LR + PV +
Sbjct: 325 TRALPPGP---------------PTGATANRLR------------------SAAEPVAST 351
Query: 439 PDSPTTPVRSLRYRRVNSPESERLSTADGRVELPERRSRMDLPGSPSRQACSSQPAQMLS 498
P S P + R ++ + ER + P S DL G RQ S PA S
Sbjct: 352 PASRIQPAGNTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTG---RQEVSRIPASQTS 408
Query: 499 VDTGH 503
V H
Sbjct: 409 VPFDH 413
>gi|68303572 casein kinase 1, alpha 1 isoform 2 [Homo sapiens]
Length = 337
Score = 172 bits (435), Expect = 2e-42
Identities = 113/328 (34%), Positives = 169/328 (51%), Gaps = 25/328 (7%)
Query: 26 ANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQ 85
A ++V ++K+++KIG G FG+IY A+++ E VA+K+ES + L E + K LQ
Sbjct: 9 AEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQ 68
Query: 86 GKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAI 145
G + G+ + +N +VM L G +L DL R FT+ T L L Q++ IE +
Sbjct: 69 GGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSR-RFTMKTVLMLADQMISRIEYV 127
Query: 146 HSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQY-TNTTGDVRPPRNVAGFRGTVR 204
H+ F+HRDIKP NF MG + K +++DFGLA++Y N T P R GT R
Sbjct: 128 HTKNFIHRDIKPDNFLMG-IGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTAR 186
Query: 205 YASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEH------- 257
YAS+NAH E R DD+ SL Y+L+ F LPW+ +K + K+KYE
Sbjct: 187 YASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATK----KQKYEKISEKKMS 242
Query: 258 ---RMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDW---- 310
+L K P+EF ++L++ L + PDY + +F + + FDW
Sbjct: 243 TPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLK 302
Query: 311 EKAGTDALLST----STSTPPQQNTRQT 334
+KA A S+ TP + T +T
Sbjct: 303 QKAAQQAASSSGQGQQAQTPTGKQTDKT 330
>gi|98986450 casein kinase 1, gamma 1 [Homo sapiens]
Length = 422
Score = 163 bits (413), Expect = 9e-40
Identities = 104/308 (33%), Positives = 163/308 (52%), Gaps = 20/308 (6%)
Query: 15 SGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVL 74
SG + +L +V ++V KKIG G FGE+ +L T E VA+K+E + L
Sbjct: 29 SGSSSSSGVL----MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQL 84
Query: 75 KMEVAVLKKL----QGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLST 130
+E K+L +G V F CG K+N +V++L G +L DL R TFTL T
Sbjct: 85 HLEYRFYKQLGSAGEGLPQVYYFGPCG---KYNAMVLELLGPSLEDLFDLCDR-TFTLKT 140
Query: 131 TLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKC-YMLDFGLARQYTNT-TG 188
L + Q+L +E +HS ++RD+KP NF +GR + +++DFGLA++Y + T
Sbjct: 141 VLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETK 200
Query: 189 DVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDK--- 245
P R GT RY S+N H +E R DDL +L +M + F G LPW+ +K
Sbjct: 201 KHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLK 260
Query: 246 ---EQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGI 302
+++G K L ++ P E +L ++ LD+F KPDY+ + ++F + +++G
Sbjct: 261 ERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGY 320
Query: 303 AENEAFDW 310
+ A+DW
Sbjct: 321 TFDYAYDW 328
>gi|68303575 casein kinase 1, alpha 1 isoform 1 [Homo sapiens]
Length = 365
Score = 161 bits (407), Expect = 4e-39
Identities = 115/355 (32%), Positives = 170/355 (47%), Gaps = 51/355 (14%)
Query: 26 ANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQ 85
A ++V ++K+++KIG G FG+IY A+++ E VA+K+ES + L E + K LQ
Sbjct: 9 AEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQ 68
Query: 86 GKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAI 145
G + G+ + +N +VM L G +L DL R FT+ T L L Q++ IE +
Sbjct: 69 GGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSR-RFTMKTVLMLADQMISRIEYV 127
Query: 146 HSVGFLHRDIKPSNFAMG---------RLPSTYRK------------------CYMLDFG 178
H+ F+HRDIKP NF MG P RK +++DFG
Sbjct: 128 HTKNFIHRDIKPDNFLMGIGRHCNKCLESPVGKRKRSMTVSTSQDPSFSGLNQLFLIDFG 187
Query: 179 LARQY-TNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQL 237
LA++Y N T P R GT RYAS+NAH E R DD+ SL Y+L+ F L
Sbjct: 188 LAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSL 247
Query: 238 PWRKIKDKEQVGMIKEKYEH----------RMLLKHMPSEFHLFLDHIASLDYFTKPDYQ 287
PW+ +K + K+KYE +L K P+EF ++L++ L + PDY
Sbjct: 248 PWQGLKAATK----KQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYM 303
Query: 288 LIMSVFENSMKERGIAENEAFDW----EKAGTDALLST----STSTPPQQNTRQT 334
+ +F + + FDW +KA A S+ TP + T +T
Sbjct: 304 YLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKT 358
>gi|21624639 casein kinase 1, alpha 1-like [Homo sapiens]
Length = 337
Score = 161 bits (407), Expect = 4e-39
Identities = 112/324 (34%), Positives = 160/324 (49%), Gaps = 27/324 (8%)
Query: 26 ANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQ 85
A VV ++K+++KIG G FG++Y + E VA+K+ES + L E + LQ
Sbjct: 9 AELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEEVAVKLESQKVKHPQLLYESKLYTILQ 68
Query: 86 GKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAI 145
G + G+ + N +VM L G +L DL R FT+ T L L Q++ IE +
Sbjct: 69 GGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSR-RFTMKTVLMLADQMISRIEYV 127
Query: 146 HSVGFLHRDIKPSNFAMGRLPSTYRKC---YMLDFGLARQYT-NTTGDVRPPRNVAGFRG 201
H+ FLHRDIKP NF MG T R C +++DFGLA++Y N T P R G
Sbjct: 128 HTKNFLHRDIKPDNFLMG----TGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIG 183
Query: 202 TVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEH---- 257
TVRYAS+NAH E R DD+ SL Y+ + F LPW+ +K + K+KYE
Sbjct: 184 TVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTK----KQKYEKISEK 239
Query: 258 ------RMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDW- 310
+L K P+EF ++L++ L + PDY + +F + + FDW
Sbjct: 240 KMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWT 299
Query: 311 ---EKAGTDALLSTSTSTPPQQNT 331
+KA A S+ Q T
Sbjct: 300 MLKQKAAQQAASSSGQGQQAQTQT 323
>gi|153791733 casein kinase 1, gamma 2 [Homo sapiens]
Length = 415
Score = 160 bits (406), Expect = 6e-39
Identities = 101/310 (32%), Positives = 159/310 (51%), Gaps = 11/310 (3%)
Query: 29 VVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKD 88
+V ++V KKIG G FGE+ +L T E VA+K+E + L +E K+L +
Sbjct: 41 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATE 100
Query: 89 HVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSV 148
V + G K+N +V++L G +L DL R TFTL T L + Q++ +E +H+
Sbjct: 101 GVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDR-TFTLKTVLMIAIQLITRMEYVHTK 159
Query: 149 GFLHRDIKPSNFAMGRLPSTYRK--CYMLDFGLARQYTN-TTGDVRPPRNVAGFRGTVRY 205
++RD+KP NF +GR P T R+ +++DFGLA++Y + T P R GT RY
Sbjct: 160 SLIYRDVKPENFLVGR-PGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARY 218
Query: 206 ASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDK------EQVGMIKEKYEHRM 259
S+N H +E R DDL +L +M + F G LPW+ +K +++G K +
Sbjct: 219 MSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEV 278
Query: 260 LLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALL 319
L ++ P E +L ++ LD+F KPDY + +F + G + +DW +
Sbjct: 279 LCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPI 338
Query: 320 STSTSTPPQQ 329
T + P Q
Sbjct: 339 GTVHTDLPSQ 348
>gi|113462010 casein kinase 1, gamma 3 isoform 4 [Homo sapiens]
Length = 455
Score = 154 bits (390), Expect = 4e-37
Identities = 96/290 (33%), Positives = 154/290 (53%), Gaps = 10/290 (3%)
Query: 29 VVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKD 88
+V ++V KKIG G FGE+ +L T E VA+K+E + L +E K+L D
Sbjct: 38 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGD 97
Query: 89 HVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSV 148
+ + G K+N +V++L G +L DL R TF+L T L + Q++ +E +HS
Sbjct: 98 GIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDR-TFSLKTVLMIAIQLISRMEYVHSK 156
Query: 149 GFLHRDIKPSNFAMGRLPS-TYRKCYMLDFGLARQYTN-TTGDVRPPRNVAGFRGTVRYA 206
++RD+KP NF +GR + T + +++DFGLA++Y + T P R GT RY
Sbjct: 157 NLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 216
Query: 207 SVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDK------EQVGMIKEKYEHRML 260
S+N H +E R DDL +L +M + F G LPW+ +K +++G K +L
Sbjct: 217 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 276
Query: 261 LKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDW 310
++ P E +L ++ LD+F KPDY + +F + +G + +DW
Sbjct: 277 CENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDW 325
>gi|113462008 casein kinase 1, gamma 3 isoform 3 [Homo sapiens]
Length = 415
Score = 154 bits (390), Expect = 4e-37
Identities = 96/290 (33%), Positives = 154/290 (53%), Gaps = 10/290 (3%)
Query: 29 VVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKD 88
+V ++V KKIG G FGE+ +L T E VA+K+E + L +E K+L D
Sbjct: 38 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGD 97
Query: 89 HVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSV 148
+ + G K+N +V++L G +L DL R TF+L T L + Q++ +E +HS
Sbjct: 98 GIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDR-TFSLKTVLMIAIQLISRMEYVHSK 156
Query: 149 GFLHRDIKPSNFAMGRLPS-TYRKCYMLDFGLARQYTN-TTGDVRPPRNVAGFRGTVRYA 206
++RD+KP NF +GR + T + +++DFGLA++Y + T P R GT RY
Sbjct: 157 NLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 216
Query: 207 SVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDK------EQVGMIKEKYEHRML 260
S+N H +E R DDL +L +M + F G LPW+ +K +++G K +L
Sbjct: 217 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 276
Query: 261 LKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDW 310
++ P E +L ++ LD+F KPDY + +F + +G + +DW
Sbjct: 277 CENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDW 325
>gi|73532780 casein kinase 1, gamma 3 isoform 2 [Homo sapiens]
Length = 423
Score = 154 bits (390), Expect = 4e-37
Identities = 96/290 (33%), Positives = 154/290 (53%), Gaps = 10/290 (3%)
Query: 29 VVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKD 88
+V ++V KKIG G FGE+ +L T E VA+K+E + L +E K+L D
Sbjct: 38 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGD 97
Query: 89 HVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSV 148
+ + G K+N +V++L G +L DL R TF+L T L + Q++ +E +HS
Sbjct: 98 GIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDR-TFSLKTVLMIAIQLISRMEYVHSK 156
Query: 149 GFLHRDIKPSNFAMGRLPS-TYRKCYMLDFGLARQYTN-TTGDVRPPRNVAGFRGTVRYA 206
++RD+KP NF +GR + T + +++DFGLA++Y + T P R GT RY
Sbjct: 157 NLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 216
Query: 207 SVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDK------EQVGMIKEKYEHRML 260
S+N H +E R DDL +L +M + F G LPW+ +K +++G K +L
Sbjct: 217 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 276
Query: 261 LKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDW 310
++ P E +L ++ LD+F KPDY + +F + +G + +DW
Sbjct: 277 CENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDW 325
>gi|73532778 casein kinase 1, gamma 3 isoform 1 [Homo sapiens]
Length = 447
Score = 154 bits (390), Expect = 4e-37
Identities = 96/290 (33%), Positives = 154/290 (53%), Gaps = 10/290 (3%)
Query: 29 VVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKD 88
+V ++V KKIG G FGE+ +L T E VA+K+E + L +E K+L D
Sbjct: 38 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGD 97
Query: 89 HVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSV 148
+ + G K+N +V++L G +L DL R TF+L T L + Q++ +E +HS
Sbjct: 98 GIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDR-TFSLKTVLMIAIQLISRMEYVHSK 156
Query: 149 GFLHRDIKPSNFAMGRLPS-TYRKCYMLDFGLARQYTN-TTGDVRPPRNVAGFRGTVRYA 206
++RD+KP NF +GR + T + +++DFGLA++Y + T P R GT RY
Sbjct: 157 NLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 216
Query: 207 SVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDK------EQVGMIKEKYEHRML 260
S+N H +E R DDL +L +M + F G LPW+ +K +++G K +L
Sbjct: 217 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 276
Query: 261 LKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDW 310
++ P E +L ++ LD+F KPDY + +F + +G + +DW
Sbjct: 277 CENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDW 325
>gi|194440713 vaccinia related kinase 2 isoform 3 [Homo sapiens]
Length = 396
Score = 100 bits (250), Expect = 7e-21
Identities = 86/290 (29%), Positives = 135/290 (46%), Gaps = 33/290 (11%)
Query: 32 DRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQ-QPKQVLKMEVAVLKKLQGKDHV 90
++W + KKIG GGFG IY A E A V + Q L E+ +++ KD +
Sbjct: 27 NQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGPLFSELKFYQRVAKKDCI 86
Query: 91 CRFI--------------GCGRNE----KFNYVVMQLQGRNLADLRRSQPRGTFTLSTTL 132
++I G G E + ++VM+ G +L + S GTF ST L
Sbjct: 87 KKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKI--SGQNGTFKKSTVL 144
Query: 133 RLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRP 192
+LG ++L+ +E IH ++H DIK +N +G + Y+ D+GL+ +Y +
Sbjct: 145 QLGIRMLDVLEYIHENEYVHGDIKAANLLLGY--KNPDQVYLADYGLSYRYCPNGNHKQY 202
Query: 193 PRNV-AGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPW-RKIKDKEQVGM 250
N G GT+ + S++AHK + R D+ L Y ++ + G+LPW + +KD V
Sbjct: 203 QENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQT 262
Query: 251 IKEKYEHRM---LLKHMPS-----EFHLFLDHIASLDYFTKPDYQLIMSV 292
K + +LK PS E FL SL Y KP+YQ + +
Sbjct: 263 AKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKI 312
>gi|194440711 vaccinia related kinase 2 isoform 2 [Homo sapiens]
Length = 485
Score = 100 bits (250), Expect = 7e-21
Identities = 86/290 (29%), Positives = 135/290 (46%), Gaps = 33/290 (11%)
Query: 32 DRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQ-QPKQVLKMEVAVLKKLQGKDHV 90
++W + KKIG GGFG IY A E A V + Q L E+ +++ KD +
Sbjct: 4 NQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGPLFSELKFYQRVAKKDCI 63
Query: 91 CRFI--------------GCGRNE----KFNYVVMQLQGRNLADLRRSQPRGTFTLSTTL 132
++I G G E + ++VM+ G +L + S GTF ST L
Sbjct: 64 KKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKI--SGQNGTFKKSTVL 121
Query: 133 RLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRP 192
+LG ++L+ +E IH ++H DIK +N +G + Y+ D+GL+ +Y +
Sbjct: 122 QLGIRMLDVLEYIHENEYVHGDIKAANLLLGY--KNPDQVYLADYGLSYRYCPNGNHKQY 179
Query: 193 PRNV-AGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPW-RKIKDKEQVGM 250
N G GT+ + S++AHK + R D+ L Y ++ + G+LPW + +KD V
Sbjct: 180 QENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQT 239
Query: 251 IKEKYEHRM---LLKHMPS-----EFHLFLDHIASLDYFTKPDYQLIMSV 292
K + +LK PS E FL SL Y KP+YQ + +
Sbjct: 240 AKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKI 289
>gi|194440709 vaccinia related kinase 2 isoform 1 [Homo sapiens]
Length = 508
Score = 100 bits (250), Expect = 7e-21
Identities = 86/290 (29%), Positives = 135/290 (46%), Gaps = 33/290 (11%)
Query: 32 DRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQ-QPKQVLKMEVAVLKKLQGKDHV 90
++W + KKIG GGFG IY A E A V + Q L E+ +++ KD +
Sbjct: 27 NQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGPLFSELKFYQRVAKKDCI 86
Query: 91 CRFI--------------GCGRNE----KFNYVVMQLQGRNLADLRRSQPRGTFTLSTTL 132
++I G G E + ++VM+ G +L + S GTF ST L
Sbjct: 87 KKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKI--SGQNGTFKKSTVL 144
Query: 133 RLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRP 192
+LG ++L+ +E IH ++H DIK +N +G + Y+ D+GL+ +Y +
Sbjct: 145 QLGIRMLDVLEYIHENEYVHGDIKAANLLLGY--KNPDQVYLADYGLSYRYCPNGNHKQY 202
Query: 193 PRNV-AGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPW-RKIKDKEQVGM 250
N G GT+ + S++AHK + R D+ L Y ++ + G+LPW + +KD V
Sbjct: 203 QENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQT 262
Query: 251 IKEKYEHRM---LLKHMPS-----EFHLFLDHIASLDYFTKPDYQLIMSV 292
K + +LK PS E FL SL Y KP+YQ + +
Sbjct: 263 AKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKI 312
>gi|194440707 vaccinia related kinase 2 isoform 1 [Homo sapiens]
Length = 508
Score = 100 bits (250), Expect = 7e-21
Identities = 86/290 (29%), Positives = 135/290 (46%), Gaps = 33/290 (11%)
Query: 32 DRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQ-QPKQVLKMEVAVLKKLQGKDHV 90
++W + KKIG GGFG IY A E A V + Q L E+ +++ KD +
Sbjct: 27 NQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGPLFSELKFYQRVAKKDCI 86
Query: 91 CRFI--------------GCGRNE----KFNYVVMQLQGRNLADLRRSQPRGTFTLSTTL 132
++I G G E + ++VM+ G +L + S GTF ST L
Sbjct: 87 KKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKI--SGQNGTFKKSTVL 144
Query: 133 RLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRP 192
+LG ++L+ +E IH ++H DIK +N +G + Y+ D+GL+ +Y +
Sbjct: 145 QLGIRMLDVLEYIHENEYVHGDIKAANLLLGY--KNPDQVYLADYGLSYRYCPNGNHKQY 202
Query: 193 PRNV-AGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPW-RKIKDKEQVGM 250
N G GT+ + S++AHK + R D+ L Y ++ + G+LPW + +KD V
Sbjct: 203 QENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQT 262
Query: 251 IKEKYEHRM---LLKHMPS-----EFHLFLDHIASLDYFTKPDYQLIMSV 292
K + +LK PS E FL SL Y KP+YQ + +
Sbjct: 263 AKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKI 312
>gi|71164884 vaccinia related kinase 2 isoform 1 [Homo sapiens]
Length = 508
Score = 100 bits (250), Expect = 7e-21
Identities = 86/290 (29%), Positives = 135/290 (46%), Gaps = 33/290 (11%)
Query: 32 DRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQ-QPKQVLKMEVAVLKKLQGKDHV 90
++W + KKIG GGFG IY A E A V + Q L E+ +++ KD +
Sbjct: 27 NQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGPLFSELKFYQRVAKKDCI 86
Query: 91 CRFI--------------GCGRNE----KFNYVVMQLQGRNLADLRRSQPRGTFTLSTTL 132
++I G G E + ++VM+ G +L + S GTF ST L
Sbjct: 87 KKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKI--SGQNGTFKKSTVL 144
Query: 133 RLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRP 192
+LG ++L+ +E IH ++H DIK +N +G + Y+ D+GL+ +Y +
Sbjct: 145 QLGIRMLDVLEYIHENEYVHGDIKAANLLLGY--KNPDQVYLADYGLSYRYCPNGNHKQY 202
Query: 193 PRNV-AGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPW-RKIKDKEQVGM 250
N G GT+ + S++AHK + R D+ L Y ++ + G+LPW + +KD V
Sbjct: 203 QENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQT 262
Query: 251 IKEKYEHRM---LLKHMPS-----EFHLFLDHIASLDYFTKPDYQLIMSV 292
K + +LK PS E FL SL Y KP+YQ + +
Sbjct: 263 AKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKI 312
>gi|4507903 vaccinia related kinase 1 [Homo sapiens]
Length = 396
Score = 94.7 bits (234), Expect = 5e-19
Identities = 86/319 (26%), Positives = 143/319 (44%), Gaps = 48/319 (15%)
Query: 29 VVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVA------LKVES---------------A 67
+ K WKV IG GGFG IY A D+ + E+V +KVE A
Sbjct: 32 MAKKEWKVGLPIGQGGFGCIYLA-DMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRA 90
Query: 68 QQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEK----FNYVVMQLQGRNLADLRRSQPR 123
+P+Q+ K K G V ++ G G ++K + +++M G +L + + +
Sbjct: 91 AKPEQIQKWIRTRKLKYLG---VPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAK 147
Query: 124 GTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQY 183
F+ T L+L +IL+ +E IH ++H DIK SN + + Y++D+GLA +Y
Sbjct: 148 -RFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNY--KNPDQVYLVDYGLAYRY 204
Query: 184 ----TNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPW 239
+ P R GT+ + S++AH R DL L Y ++++ G LPW
Sbjct: 205 CPEGVHKEYKEDPKRC---HDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPW 261
Query: 240 R-KIKDKEQVGMIKEKYEHRMLL--------KHMPSEFHLFLDHIASLDYFTKPDYQLIM 290
+KD + V K +Y + K+ P E +++ + LDY KP Y+ +
Sbjct: 262 EDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLR 321
Query: 291 SVFENSMKERGIAENEAFD 309
+ +K G ++ D
Sbjct: 322 DILLQGLKAIGSKDDGKLD 340
>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
[Homo sapiens]
Length = 1130
Score = 86.7 bits (213), Expect = 1e-16
Identities = 147/677 (21%), Positives = 248/677 (36%), Gaps = 87/677 (12%)
Query: 32 DRWKVLK-------KIGGGGFGEIYEAMDLLTRENVALKV--ESAQQPKQVLKMEVAVLK 82
D+W++ + K+GGG +GE+YE + VA+K E + ++ LK E AV+K
Sbjct: 233 DKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLK-EAAVMK 291
Query: 83 KLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESI 142
+++ + V C R F + + NL D R R L + QI ++
Sbjct: 292 EIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAM 351
Query: 143 EAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGT 202
E + F+HRD+ N +G + DFGL+R T T AG +
Sbjct: 352 EYLEKKNFIHRDLAARNCLVGE----NHLVKVADFGLSRLMTGDTYTAH-----AGAKFP 402
Query: 203 VRYASVNAHKNREMGRHDDLWSLFYMLVEFAV-GQLPWRKIKDKEQVGMIKEKYEHRMLL 261
+++ + + + D+W+ +L E A G P+ I D QV + EK
Sbjct: 403 IKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGI-DLSQVYELLEKDYRMERP 461
Query: 262 KHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALLST 321
+ P + + + + +P + I FE +E I++ + K G +ST
Sbjct: 462 EGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVST 521
Query: 322 STSTPP-QQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPILPGRPSE 380
P TR + + T VP E QGE ++ P + P P +
Sbjct: 522 LLQAPELPTKTRTSRRAAEHRDTTDVP-----EMPHSKGQGES-DPLDHEPAVSPLLPRK 575
Query: 381 GLGPSPHLVPHPGGPEAEVWEETDVNRNKLRINIGKSPCVEEEQSRGMGVPSSPVRAPPD 440
GP PE + E+ + + N+ + +++++
Sbjct: 576 ERGP----------PEGGLNEDERLLPKDKKTNLFSALIKKKKKT--------------- 610
Query: 441 SPTTPVRSLRYRRVN-SPESERLSTADGR-----------------VELPERRSRMDLPG 482
+PT P RS +R ++ PE +GR + P+ + +P
Sbjct: 611 APTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPN 670
Query: 483 SPSRQACSS---QPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFRS-VPLAEEEDF 538
R++ S P T + R A+G + S + L + S VP ++
Sbjct: 671 GALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKD-- 728
Query: 539 DSKEWVIIDKETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLGAEPTVRPRGR 598
EW + +L+ + ST G E L P GE R TV P R
Sbjct: 729 --TEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPAL-PRKRAGENRSDQVTRGTVTPPPR 785
Query: 599 SMQALAE------EDLQHLPPQPLPPQLSQGDGRSETSQPPTPGSPSHSPLHSGPR-PRR 651
++ E +D+ P PP L+ R + + P G P G
Sbjct: 786 LVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTP 845
Query: 652 RESDPTGPQRQVFSVAP 668
++P P + S AP
Sbjct: 846 AAAEPVTPTSKAGSGAP 862
Score = 36.6 bits (83), Expect = 0.16
Identities = 47/191 (24%), Positives = 69/191 (36%), Gaps = 37/191 (19%)
Query: 1100 RLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAAALPRKSGRAAATRSRIPRP 1159
R + +A + EE + S + +E TP S+ + P + + A SR+ R
Sbjct: 819 RRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRR- 877
Query: 1160 IGLRMPMPVAAQQPASRSHGAAPALDTAITSRLQLQTPP---GSATAADLRPKQPPGRGL 1216
+ +P D SRL+ PP SA A +P Q P +
Sbjct: 878 ---------------HKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQE- 921
Query: 1217 GPGRAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRRESPSPSHQARPGVPPPRGV 1276
G A GA+ A S A N+ A+ SQ + P P P P+
Sbjct: 922 AAGEAVLGAKTKA-------TSLVDAVNSDAAKPSQPGEGLKKP-----VLPATPKPQS- 968
Query: 1277 PPARAQPDGTP 1287
A+P GTP
Sbjct: 969 ----AKPSGTP 975
>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
[Homo sapiens]
Length = 1149
Score = 86.7 bits (213), Expect = 1e-16
Identities = 147/677 (21%), Positives = 248/677 (36%), Gaps = 87/677 (12%)
Query: 32 DRWKVLK-------KIGGGGFGEIYEAMDLLTRENVALKV--ESAQQPKQVLKMEVAVLK 82
D+W++ + K+GGG +GE+YE + VA+K E + ++ LK E AV+K
Sbjct: 252 DKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLK-EAAVMK 310
Query: 83 KLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESI 142
+++ + V C R F + + NL D R R L + QI ++
Sbjct: 311 EIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAM 370
Query: 143 EAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGT 202
E + F+HRD+ N +G + DFGL+R T T AG +
Sbjct: 371 EYLEKKNFIHRDLAARNCLVGE----NHLVKVADFGLSRLMTGDTYTAH-----AGAKFP 421
Query: 203 VRYASVNAHKNREMGRHDDLWSLFYMLVEFAV-GQLPWRKIKDKEQVGMIKEKYEHRMLL 261
+++ + + + D+W+ +L E A G P+ I D QV + EK
Sbjct: 422 IKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGI-DLSQVYELLEKDYRMERP 480
Query: 262 KHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALLST 321
+ P + + + + +P + I FE +E I++ + K G +ST
Sbjct: 481 EGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVST 540
Query: 322 STSTPP-QQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPILPGRPSE 380
P TR + + T VP E QGE ++ P + P P +
Sbjct: 541 LLQAPELPTKTRTSRRAAEHRDTTDVP-----EMPHSKGQGES-DPLDHEPAVSPLLPRK 594
Query: 381 GLGPSPHLVPHPGGPEAEVWEETDVNRNKLRINIGKSPCVEEEQSRGMGVPSSPVRAPPD 440
GP PE + E+ + + N+ + +++++
Sbjct: 595 ERGP----------PEGGLNEDERLLPKDKKTNLFSALIKKKKKT--------------- 629
Query: 441 SPTTPVRSLRYRRVN-SPESERLSTADGR-----------------VELPERRSRMDLPG 482
+PT P RS +R ++ PE +GR + P+ + +P
Sbjct: 630 APTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPN 689
Query: 483 SPSRQACSS---QPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFRS-VPLAEEEDF 538
R++ S P T + R A+G + S + L + S VP ++
Sbjct: 690 GALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKD-- 747
Query: 539 DSKEWVIIDKETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLGAEPTVRPRGR 598
EW + +L+ + ST G E L P GE R TV P R
Sbjct: 748 --TEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPAL-PRKRAGENRSDQVTRGTVTPPPR 804
Query: 599 SMQALAE------EDLQHLPPQPLPPQLSQGDGRSETSQPPTPGSPSHSPLHSGPR-PRR 651
++ E +D+ P PP L+ R + + P G P G
Sbjct: 805 LVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTP 864
Query: 652 RESDPTGPQRQVFSVAP 668
++P P + S AP
Sbjct: 865 AAAEPVTPTSKAGSGAP 881
Score = 36.6 bits (83), Expect = 0.16
Identities = 47/191 (24%), Positives = 69/191 (36%), Gaps = 37/191 (19%)
Query: 1100 RLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAAALPRKSGRAAATRSRIPRP 1159
R + +A + EE + S + +E TP S+ + P + + A SR+ R
Sbjct: 838 RRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRR- 896
Query: 1160 IGLRMPMPVAAQQPASRSHGAAPALDTAITSRLQLQTPP---GSATAADLRPKQPPGRGL 1216
+ +P D SRL+ PP SA A +P Q P +
Sbjct: 897 ---------------HKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQE- 940
Query: 1217 GPGRAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRRESPSPSHQARPGVPPPRGV 1276
G A GA+ A S A N+ A+ SQ + P P P P+
Sbjct: 941 AAGEAVLGAKTKA-------TSLVDAVNSDAAKPSQPGEGLKKP-----VLPATPKPQS- 987
Query: 1277 PPARAQPDGTP 1287
A+P GTP
Sbjct: 988 ----AKPSGTP 994
>gi|15011880 serine/threonine protein kinase MST4 isoform 1 [Homo
sapiens]
Length = 416
Score = 85.9 bits (211), Expect = 2e-16
Identities = 89/338 (26%), Positives = 155/338 (45%), Gaps = 30/338 (8%)
Query: 37 LKKIGGGGFGEIYEAMDLLTRENVALKV---ESAQQPKQVLKMEVAVLKKLQGKDHVCRF 93
L++IG G FGE+++ +D T++ VA+K+ E A+ + ++ E+ VL + +V ++
Sbjct: 27 LERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCD-SSYVTKY 85
Query: 94 IGCGRNEKFNYVVMQ-LQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLH 152
G +++M+ L G + DL R+ P F ++T L K+IL+ ++ +HS +H
Sbjct: 86 YGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATML---KEILKGLDYLHSEKKIH 142
Query: 153 RDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHK 212
RDIK +N L S + DFG+A Q T D + RN F GT + + +
Sbjct: 143 RDIKAANV----LLSEQGDVKLADFGVAGQLT----DTQIKRNT--FVGTPFWMAPEVIQ 192
Query: 213 NREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFL 272
D+WSL +E A G+ P + + +I K L+ F F+
Sbjct: 193 QSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLI-PKNNPPTLVGDFTKSFKEFI 251
Query: 273 DHIASLDYFTKPDYQLIMS---VFENSMKERGIAE--NEAFDWEKAG-----TDALLSTS 322
D + D +P + ++ + +NS K + E + W+ G +D+ S S
Sbjct: 252 DACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELIDRFKRWKAEGHSDDESDSEGSDS 311
Query: 323 TSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQ 360
ST + NT + F V P P + +D++Q
Sbjct: 312 ESTSRENNTHPEWS-FTTVRKKPDPKKVQNGAEQDLVQ 348
>gi|209862855 vaccinia related kinase 2 isoform 6 [Homo sapiens]
Length = 390
Score = 82.8 bits (203), Expect = 2e-15
Identities = 62/198 (31%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Query: 105 VVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGR 164
+VM+ G +L + S GTF ST L+LG ++L+ +E IH ++H DIK +N +G
Sbjct: 1 MVMERLGIDLQKI--SGQNGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY 58
Query: 165 LPSTYRKCYMLDFGLARQYTNTTGDVRPPRNV-AGFRGTVRYASVNAHKNREMGRHDDLW 223
+ Y+ D+GL+ +Y + N G GT+ + S++AHK + R D+
Sbjct: 59 --KNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVE 116
Query: 224 SLFYMLVEFAVGQLPW-RKIKDKEQVGMIKEKYEHRM---LLKHMPS-----EFHLFLDH 274
L Y ++ + G+LPW + +KD V K + +LK PS E FL
Sbjct: 117 ILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEIAQFLVC 176
Query: 275 IASLDYFTKPDYQLIMSV 292
SL Y KP+YQ + +
Sbjct: 177 AHSLAYDEKPNYQALKKI 194
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 82.0 bits (201), Expect = 3e-15
Identities = 72/202 (35%), Positives = 94/202 (46%), Gaps = 35/202 (17%)
Query: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAA--VALGEVLGPRSGSS 789
+EEEEEEEEDEEEEEE+EEEEEEEEEEEEEEEEEEEEEEE AA V E S
Sbjct: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQK 324
Query: 790 S---EGSERSTDRSQEGAPSTLLADDQK--ESRGRASMADGDLEPEEGSKTLVLVSPGDM 844
+ G E + + + + +DD K ++ R S + E ++ +++ G++
Sbjct: 325 APELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQD------MMTRGNL 378
Query: 845 KKSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVL------------- 891
L + P E+ SQL + EPG + L
Sbjct: 379 GLLEQAIALKAEQVRTVCEPGCPPAEQ-----SQLGLGEPGKAAKPLDTVRKSYYSKDPS 433
Query: 892 ---KSEPKPPGPGAGLGAGTVT 910
K E K P PG G G VT
Sbjct: 434 RAEKREIKCPTPGCD-GTGHVT 454
Score = 66.6 bits (161), Expect = 1e-10
Identities = 36/67 (53%), Positives = 45/67 (67%), Gaps = 4/67 (5%)
Query: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEE----EEEEEAAAAVALGEV 781
+ + +EEEEEEEE+EEEEEE+EEEEEEEEEEEEEEE +E+ +A E+
Sbjct: 269 EEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPEL 328
Query: 782 LGPRSGS 788
GP S S
Sbjct: 329 RGPESPS 335
>gi|110349738 serine/threonine kinase 24 isoform b [Homo sapiens]
Length = 431
Score = 79.0 bits (193), Expect = 3e-14
Identities = 62/206 (30%), Positives = 105/206 (50%), Gaps = 18/206 (8%)
Query: 37 LKKIGGGGFGEIYEAMDLLTRENVALKV---ESAQQPKQVLKMEVAVLKKLQGKDHVCRF 93
L+KIG G FGE+++ +D T++ VA+K+ E A+ + ++ E+ VL + +V ++
Sbjct: 27 LEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCD-SPYVTKY 85
Query: 94 IGCGRNEKFNYVVMQ-LQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLH 152
G + +++M+ L G + DL P ++T LR +IL+ ++ +HS +H
Sbjct: 86 YGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILR---EILKGLDYLHSEKKIH 142
Query: 153 RDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHK 212
RDIK +N L S + + + DFG+A Q T D + RN F GT + + K
Sbjct: 143 RDIKAANV----LLSEHGEVKLADFGVAGQLT----DTQIKRNT--FVGTPFWMAPEVIK 192
Query: 213 NREMGRHDDLWSLFYMLVEFAVGQLP 238
D+WSL +E A G+ P
Sbjct: 193 QSAYDSKADIWSLGITAIELARGEPP 218
>gi|20070158 serine/threonine kinase 24 isoform a [Homo sapiens]
Length = 443
Score = 79.0 bits (193), Expect = 3e-14
Identities = 62/206 (30%), Positives = 105/206 (50%), Gaps = 18/206 (8%)
Query: 37 LKKIGGGGFGEIYEAMDLLTRENVALKV---ESAQQPKQVLKMEVAVLKKLQGKDHVCRF 93
L+KIG G FGE+++ +D T++ VA+K+ E A+ + ++ E+ VL + +V ++
Sbjct: 39 LEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCD-SPYVTKY 97
Query: 94 IGCGRNEKFNYVVMQ-LQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLH 152
G + +++M+ L G + DL P ++T LR +IL+ ++ +HS +H
Sbjct: 98 YGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILR---EILKGLDYLHSEKKIH 154
Query: 153 RDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHK 212
RDIK +N L S + + + DFG+A Q T D + RN F GT + + K
Sbjct: 155 RDIKAANV----LLSEHGEVKLADFGVAGQLT----DTQIKRNT--FVGTPFWMAPEVIK 204
Query: 213 NREMGRHDDLWSLFYMLVEFAVGQLP 238
D+WSL +E A G+ P
Sbjct: 205 QSAYDSKADIWSLGITAIELARGEPP 230
>gi|21361358 serine/threonine kinase 25 [Homo sapiens]
Length = 426
Score = 78.2 bits (191), Expect = 5e-14
Identities = 63/206 (30%), Positives = 102/206 (49%), Gaps = 18/206 (8%)
Query: 37 LKKIGGGGFGEIYEAMDLLTRENVALKV---ESAQQPKQVLKMEVAVLKKLQGKDHVCRF 93
L +IG G FGE+Y+ +D T+E VA+K+ E A+ + ++ E+ VL + ++ R+
Sbjct: 23 LDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCD-SPYITRY 81
Query: 94 IGCGRNEKFNYVVMQ-LQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLH 152
G +++M+ L G + DL + P ++T LR +IL+ ++ +HS +H
Sbjct: 82 FGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILR---EILKGLDYLHSERKIH 138
Query: 153 RDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHK 212
RDIK +N L S + DFG+A Q T D + RN F GT + + K
Sbjct: 139 RDIKAANV----LLSEQGDVKLADFGVAGQLT----DTQIKRNT--FVGTPFWMAPEVIK 188
Query: 213 NREMGRHDDLWSLFYMLVEFAVGQLP 238
D+WSL +E A G+ P
Sbjct: 189 QSAYDFKADIWSLGITAIELAKGEPP 214
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 77.8 bits (190), Expect = 6e-14
Identities = 85/298 (28%), Positives = 116/298 (38%), Gaps = 50/298 (16%)
Query: 611 LPPQPLPPQLSQGDGRSETSQPPTPGSPSHSPLHSGPRPRRRESD--PTGPQRQVFSVAP 668
LPP P PP + P P +P+ P S P P + E + P P P
Sbjct: 795 LPPLPPPPP---------SGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPP 845
Query: 669 PFEVNGLPRAVPLSLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLAPVQPQ 728
P V G P++LP +L+ G L + L +
Sbjct: 846 PPPVPG-----PVTLP-------------PPQLVPEGTPGGGGPPAL---EEDLTVININ 884
Query: 729 ANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEE--EEEEEEEEAAAAVALGEVLGPRS 786
++ +EEEEEEEE+EEEEEE+EEEE+ EEEEE+EEE EEEEEEEE E
Sbjct: 885 SSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEE-----EFEEEFEEEE 939
Query: 787 GSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVSPG-DMK 845
G E E + +E + E E EEG+ + P
Sbjct: 940 GELEEEEEEEDEEEEE----------ELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPP 989
Query: 846 KSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPKPPGPGAG 903
+SP + P+P+ G L + + P L S + E + P AG
Sbjct: 990 ESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAG 1047
Score = 57.8 bits (138), Expect = 7e-08
Identities = 113/467 (24%), Positives = 162/467 (34%), Gaps = 73/467 (15%)
Query: 326 PPQQNTRQTAAMFGVVNVTP--VPGDLLRE--NTEDVLQGEHLSDQENAPPILPGRPSEG 381
PP ++ G+V+V P +PG + ED + L+ PP +P P E
Sbjct: 702 PPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPI----LAPSGTPPPTIP--PDET 755
Query: 382 LG---PSPHLVPHPG--GPEAEVWEETDVNRNKLRINIGKSPCVEEEQSRGMGVPSSPVR 436
G P P V + + E+ E+D + + + + G P S P +P
Sbjct: 756 FGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTG 815
Query: 437 APPDSPTTPVRSLRYRRVNSPESERLSTADGRVELPERRSRMDLPGSPSRQACSSQPAQM 496
P SP P + E E L A G + P P P + P Q+
Sbjct: 816 PPTASPPVPAKE---------EPEELPAAPGPLPPPPP------PPPPVPGPVTLPPPQL 860
Query: 497 LSVDTGHADRQASGRMDVSASVEQEALSNAFRSVPLAEEEDFDSKEWVIIDKETELKDFP 556
+ T G A E + N S EEE+ + +E ++E E +DF
Sbjct: 861 VPEGT-------PGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEE--EEEEEEEDFE 911
Query: 557 PGAEPSTSGTTDEEPEELRPLPEEGEERRRLGAEPTVRPRGRSMQALAEEDLQHLPPQPL 616
E +EE EE E EE L E + EDL+
Sbjct: 912 EEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLE------- 964
Query: 617 PPQLSQGDGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFE----V 672
G E PP P P P P + E +P P + P E
Sbjct: 965 ---FGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPE-PGLLLEVEEPGTEEERGA 1020
Query: 673 NGLPRAVPLSLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLAPVQPQANGK 732
+ P P +LP Q V R G S PQ L +P A
Sbjct: 1021 DTAPTLAPEALPSQ----------------GEVEREGESPAAGPPPQ-ELVEEEPSAPPT 1063
Query: 733 --EEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVA 777
EEE E+ D+ + + EEE E E E E +E+E+++ AA +A
Sbjct: 1064 LLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLA 1110
Score = 37.7 bits (86), Expect = 0.073
Identities = 102/489 (20%), Positives = 145/489 (29%), Gaps = 72/489 (14%)
Query: 841 PGDMKKSPVTAELAPDPDLGTLAALTP-QHERPQP--TGSQLDVSEPGTLSSVLKSEPKP 897
PG M P P G + + P RP P T + L +S PG +S + P P
Sbjct: 668 PGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGP 727
Query: 898 PGPGAGLGAGTVTTGVGGVAVTSSPFTKVERTFVHIAEKTHLNVMSSGGQALR------S 951
AG + G T P + TF GG+ R
Sbjct: 728 ENHRAGSNEDPILAPSG----TPPPTIPPDETF--------------GGRVPRPAFVHYD 769
Query: 952 EEFSAGGELGLELASDGGAVEEGARAPLENGLALSGLNGAEIEGSALSGAPRETPSEMAT 1011
+E ++ E+ LE SD V P L +GA A +G P +P A
Sbjct: 770 KEEASDVEISLESDSDDSVVIVPEGLP---PLPPPPPSGATPPPIAPTGPPTASPPVPAK 826
Query: 1012 NSLPNGPALADGPAPVSPLEPSPEKVATISPRRHAMPGSRPRSRIPVLLSEEDT----GS 1067
PA A GP P P P P P +P P P L E+ T S
Sbjct: 827 EEPEELPA-APGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININS 885
Query: 1068 EPSGSLSAKERWSKRARPQQDLARLVMEKRQGRLLLRLASGASSSSSEEQRRASETLSGT 1127
+E + +++ E+ EE L
Sbjct: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEE 945
Query: 1128 GSEEDTPASEPAAALPRKSGRAAA--TRSRIPRPIGLRMPMPVAAQQPASRSHGAAPALD 1185
EED E + A P P L +P P P +
Sbjct: 946 EEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPK-----VQPEPE 1000
Query: 1186 TAITSRLQLQTP-----PGSATAADLRPKQPPGRGLGPGRAQAGARPPAPRS-------- 1232
L+++ P G+ TA L P+ P +G ++ A P P+
Sbjct: 1001 PEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSA 1060
Query: 1233 -PRL--------------PASTSAARNASASPRSQSLSRRESPSPSHQARPGV--PPPRG 1275
P L P T A +++L +E + + PP
Sbjct: 1061 PPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDE 1120
Query: 1276 VPPARAQPD 1284
PP +PD
Sbjct: 1121 KPPPPTEPD 1129
Score = 37.7 bits (86), Expect = 0.073
Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Query: 1211 PPGRGLGPGRAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRRESPSPSHQARPGV 1270
P G P +GA PP P +P P + S A P + P P P V
Sbjct: 792 PEGLPPLPPPPPSGATPP-PIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPP-V 849
Query: 1271 PPPRGVPPARAQPDGTPSPGG 1291
P P +PP + P+GTP GG
Sbjct: 850 PGPVTLPPPQLVPEGTPGGGG 870
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,136,826
Number of Sequences: 37866
Number of extensions: 4248605
Number of successful extensions: 148260
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1742
Number of HSP's successfully gapped in prelim test: 2409
Number of HSP's that attempted gapping in prelim test: 42806
Number of HSP's gapped (non-prelim): 46668
length of query: 1321
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1207
effective length of database: 13,930,794
effective search space: 16814468358
effective search space used: 16814468358
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.