Guide to the Human Genome
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Search of human proteins with 58530853

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|58530853 growth hormone releasing hormone receptor isoform b
precursor [Homo sapiens]
         (337 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|58530853 growth hormone releasing hormone receptor isoform b ...   714   0.0  
gi|58530851 growth hormone releasing hormone receptor isoform a ...   688   0.0  
gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]   265   3e-71
gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]   258   5e-69
gi|114205383 secretin receptor precursor [Homo sapiens]               254   6e-68
gi|29171759 adenylate cyclase activating polypeptide 1 (pituitar...   249   3e-66
gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]    186   3e-47
gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapi...   176   3e-44
gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]          167   1e-41
gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]    165   6e-41
gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]     164   1e-40
gi|4503947 glucagon receptor [Homo sapiens]                           160   1e-39
gi|223717985 corticotropin releasing hormone receptor 1 isoform ...   125   7e-29
gi|19923245 corticotropin releasing hormone receptor 1 isoform 2...   125   7e-29
gi|32307159 corticotropin releasing hormone receptor 2 [Homo sap...   119   4e-27
gi|4502547 calcitonin receptor [Homo sapiens]                         109   3e-24
gi|223717971 corticotropin releasing hormone receptor 1 isoform ...   109   3e-24
gi|223717978 corticotropin releasing hormone receptor 1 isoform ...   108   5e-24
gi|5031621 calcitonin receptor-like [Homo sapiens]                    105   4e-23
gi|133930786 egf-like module-containing mucin-like receptor 3 [H...    57   2e-08
gi|163792198 latrophilin 3 precursor [Homo sapiens]                    57   3e-08
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]           56   5e-08
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]           56   5e-08
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s...    54   2e-07
gi|45433552 G protein-coupled receptor 133 [Homo sapiens]              54   2e-07
gi|23397681 egf-like module containing, mucin-like, hormone rece...    52   1e-06
gi|23397693 egf-like module containing, mucin-like, hormone rece...    52   1e-06
gi|23397691 egf-like module containing, mucin-like, hormone rece...    52   1e-06
gi|23397689 egf-like module containing, mucin-like, hormone rece...    52   1e-06
gi|23397687 egf-like module containing, mucin-like, hormone rece...    52   1e-06

>gi|58530853 growth hormone releasing hormone receptor isoform b
           precursor [Homo sapiens]
          Length = 337

 Score =  714 bits (1844), Expect = 0.0
 Identities = 337/337 (100%), Positives = 337/337 (100%)

Query: 1   MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD 60
           MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD
Sbjct: 1   MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD 60

Query: 61  GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA 120
           GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA
Sbjct: 61  GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA 120

Query: 121 EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF 180
           EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF
Sbjct: 121 EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF 180

Query: 181 LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR 240
           LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR
Sbjct: 181 LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR 240

Query: 241 AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF 300
           AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF
Sbjct: 241 AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF 300

Query: 301 LNIIRILVRKLEPAQGSLHTQSQYWYCVFVSGDTGKG 337
           LNIIRILVRKLEPAQGSLHTQSQYWYCVFVSGDTGKG
Sbjct: 301 LNIIRILVRKLEPAQGSLHTQSQYWYCVFVSGDTGKG 337


>gi|58530851 growth hormone releasing hormone receptor isoform a
           precursor [Homo sapiens]
          Length = 423

 Score =  688 bits (1776), Expect = 0.0
 Identities = 325/325 (100%), Positives = 325/325 (100%)

Query: 1   MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD 60
           MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD
Sbjct: 1   MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD 60

Query: 61  GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA 120
           GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA
Sbjct: 61  GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA 120

Query: 121 EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF 180
           EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF
Sbjct: 121 EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF 180

Query: 181 LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR 240
           LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR
Sbjct: 181 LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR 240

Query: 241 AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF 300
           AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF
Sbjct: 241 AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF 300

Query: 301 LNIIRILVRKLEPAQGSLHTQSQYW 325
           LNIIRILVRKLEPAQGSLHTQSQYW
Sbjct: 301 LNIIRILVRKLEPAQGSLHTQSQYW 325


>gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]
          Length = 457

 Score =  265 bits (678), Expect = 3e-71
 Identities = 134/305 (43%), Positives = 181/305 (59%), Gaps = 7/305 (2%)

Query: 14  LSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEW 73
           L P       +  ECD++  +      CL+ A+ + N T+GC   WD L CWP    G+ 
Sbjct: 23  LGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQ-LENETIGCSKMWDNLTCWPATPRGQV 81

Query: 74  VTLPCPDFFSHFSSESGA-VKRDCTITGWSEPFP-PYPVACPVPLELLAEEES---YFST 128
           V L CP  F  FSS  G  V R CT  GW+   P PYP+AC +  +  + +E    ++ +
Sbjct: 82  VVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASLDEQQTMFYGS 141

Query: 129 VKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFH 188
           VK  YT+G+ +S+  L VA  IL   R+LHC RNY+H  LF +FIL+A AVF+KD ALF 
Sbjct: 142 VKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFD 201

Query: 189 SDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLA 248
           S ++D CS  +V CK ++    +  M NF WLL E +YL  LLA +  S R+ FW  +L 
Sbjct: 202 SGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILI 261

Query: 249 GWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILV 308
           GWG+P  FT  W   ++ FED  CWD  ++S  WWIIKGPI+ S+ VNF LF+ IIRIL+
Sbjct: 262 GWGVPSTFTMVWTIARIHFEDYGCWDTINSS-LWWIIKGPILTSILVNFILFICIIRILL 320

Query: 309 RKLEP 313
           +KL P
Sbjct: 321 QKLRP 325


>gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]
          Length = 438

 Score =  258 bits (659), Expect = 5e-69
 Identities = 127/304 (41%), Positives = 181/304 (59%), Gaps = 4/304 (1%)

Query: 24  MHPECDFITQLREDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFS 83
           +HPEC F  +++E+E+ C +           C   WD + CW  A  GE VT+PCP  FS
Sbjct: 21  IHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNITCWRPANVGETVTVPCPKVFS 80

Query: 84  HFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVA 143
           +F S++G + ++CT  GWSE FP +  AC         + +++  VK IYT+G+S+S+++
Sbjct: 81  NFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMS 140

Query: 144 LFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDTDHC---SFSTV 200
           L     IL   R+LHC RNY+H  LF +FIL+A +V +KD  L+ S  T HC     S V
Sbjct: 141 LATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWV 200

Query: 201 LCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTW 260
            CK+S+    +  M NF WLL E +YL+ LL +  P  RR F   +L GWGLP +  G W
Sbjct: 201 GCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLP-PRRCFLAYLLIGWGLPTVCIGAW 259

Query: 261 VSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHT 320
            + +L  ED  CWD +D S  WW+I+ PI++S+ VNF LF++IIRIL++KL       + 
Sbjct: 260 TAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGND 319

Query: 321 QSQY 324
           QSQY
Sbjct: 320 QSQY 323


>gi|114205383 secretin receptor precursor [Homo sapiens]
          Length = 440

 Score =  254 bits (650), Expect = 6e-68
 Identities = 126/306 (41%), Positives = 178/306 (58%), Gaps = 9/306 (2%)

Query: 28  CDFITQLREDESACLQAAEEMPNTTLG-------CPATWDGLLCWPTAGSGEWVTLPCPD 80
           CD +  L E++  CLQ         LG       C   WD + CWP++  G  V + CP 
Sbjct: 32  CDVLQVLWEEQDQCLQELSREQTGDLGTEQPVPGCEGMWDNISCWPSSVPGRMVEVECPR 91

Query: 81  FFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEE--SYFSTVKIIYTVGHS 138
           F    +S +G++ R+CT  GWSE FP   +AC V +   + E+  SY   +K++YTVG+S
Sbjct: 92  FLRMLTSRNGSLFRNCTQDGWSETFPRPNLACGVNVNDSSNEKRHSYLLKLKVMYTVGYS 151

Query: 139 ISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDTDHCSFS 198
            S+V L VA+ IL A RRLHC RNY+H  LF +FIL+A + F+KDA LF SDD  +C   
Sbjct: 152 SSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAH 211

Query: 199 TVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTG 258
              CK+ +    +  M N+SWLL E +YL+ LLA +  S R+     V  GWG P +F  
Sbjct: 212 RAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVA 271

Query: 259 TWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSL 318
            W   +   ED+ CWD++  +  WWII+GP++LS+ +NF LF+NI+RIL+RKL   +   
Sbjct: 272 LWAIARHFLEDVGCWDINANASIWWIIRGPVILSILINFILFINILRILMRKLRTQETRG 331

Query: 319 HTQSQY 324
           +  S Y
Sbjct: 332 NEVSHY 337


>gi|29171759 adenylate cyclase activating polypeptide 1 (pituitary)
           receptor type I precursor [Homo sapiens]
          Length = 468

 Score =  249 bits (635), Expect = 3e-66
 Identities = 125/320 (39%), Positives = 183/320 (57%), Gaps = 35/320 (10%)

Query: 24  MHPECDFITQLREDESACL---QAAEEMP---NTTLGCPATWDGLLCWPTAGSGEWVTLP 77
           MH +C F    +++++ CL   Q A E+    +++ GCP  WD + CW  A  GE V + 
Sbjct: 21  MHSDCIF----KKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVLVS 76

Query: 78  CPDFFSHFS-----------------------SESGAVKRDCTITGWSEPFPPYPVACPV 114
           CP+ F  F+                       S+ G V R+CT  GWSEPFP Y  AC  
Sbjct: 77  CPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGF 136

Query: 115 PL--ELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTF 172
                   +++ Y+ +VK +YTVG+S S+V L  A+ IL   R+LHC RN++H  LF +F
Sbjct: 137 DEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSF 196

Query: 173 ILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLA 232
           +L+A +VF+KD  L+   D++HC  STV CK  +   H+  ++N+ WL  E +YL  LL 
Sbjct: 197 MLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLV 256

Query: 233 STSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLS 292
            T    RR F+W  + GWG P +    W + +L F+D  CWD++D++  WW+IKGP+V S
Sbjct: 257 ETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGS 316

Query: 293 VGVNFGLFLNIIRILVRKLE 312
           + VNF LF+ II ILV+KL+
Sbjct: 317 IMVNFVLFIGIIVILVQKLQ 336


>gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]
          Length = 593

 Score =  186 bits (471), Expect = 3e-47
 Identities = 105/298 (35%), Positives = 150/298 (50%), Gaps = 30/298 (10%)

Query: 55  CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA--- 111
           C   WD +LCWP    GE V +PCPD+   F+ +  A +R C   G  E  P +      
Sbjct: 108 CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRR-CDRNGSWELVPGHNRTWAN 166

Query: 112 ---CPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQL 168
              C   L     E   F  + +IYTVG+S+S+ +L VA+ IL   RRLHC RNY+H  L
Sbjct: 167 YSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHL 226

Query: 169 FTTFILKAGAVFLKDAALFHSDDTDHCSFST---------------------VLCKVSVA 207
           F +F+L+A ++F+KDA L+     D     T                       C+V+V 
Sbjct: 227 FLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVT 286

Query: 208 ASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAF 267
              +   TN+ W+L E +YL+ L+     S ++  W   + GWGLP +F   WVS +   
Sbjct: 287 FFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATL 346

Query: 268 EDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKL-EPAQGSLHTQSQY 324
            +  CWDL   +   WII+ PI+ S+ +NF LF+NI+R+L  KL E   G   T+ QY
Sbjct: 347 ANTGCWDLSSGNKK-WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQY 403


>gi|4758438 glucagon-like peptide 2 receptor precursor [Homo
           sapiens]
          Length = 553

 Score =  176 bits (446), Expect = 3e-44
 Identities = 101/296 (34%), Positives = 154/296 (52%), Gaps = 20/296 (6%)

Query: 38  ESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSES-GAVKRDC 96
           + ACL+   + P+    C  T+D  +CWP +  G  V++PCP +   +S ES G   R C
Sbjct: 80  KQACLRDLLKEPSGIF-CNGTFDQYVCWPHSSPGN-VSVPCPSYLPWWSEESSGRAYRHC 137

Query: 97  TITG-WSEPFPPYPV-----ACPVPLELLAEEESY--FSTVKIIYTVGHSISIVALFVAI 148
              G W        +      C          + Y   ST++++YTVG+S S+++LF+A+
Sbjct: 138 LAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLAL 197

Query: 149 TILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDT---------DHCSFST 199
           T+L+ LR+LHC RNY+H  LF +FIL+  AV +KD   ++S             + S  +
Sbjct: 198 TLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMS 257

Query: 200 VLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGT 259
             C+      H+    N+ WLL E +YL+ LL  T    RR +   +L GW  PVLF   
Sbjct: 258 TSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVP 317

Query: 260 WVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQ 315
           W   +   E+  CW  +     WWII+GP++L V VNF +FL I+++L+ KL+  Q
Sbjct: 318 WGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQ 373


>gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]
          Length = 463

 Score =  167 bits (423), Expect = 1e-41
 Identities = 107/301 (35%), Positives = 150/301 (49%), Gaps = 19/301 (6%)

Query: 31  ITQLREDESACLQAAEE--MPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSS- 87
           + + RE    C ++  E   P T L C  T+D   CWP    G +V + CP +    SS 
Sbjct: 36  VQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSV 95

Query: 88  ESGAVKRDCTITG-W------SEPFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSIS 140
             G V R CT  G W      S P+              +  E     + IIYTVG+++S
Sbjct: 96  PQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALS 155

Query: 141 IVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAAL--FHSDDTDHCSFS 198
             AL +A  IL+  R LHC RNY+H  LF +FIL+A +VF+KDAAL   +S       + 
Sbjct: 156 FSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWD 215

Query: 199 TVL-------CKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWG 251
            +L       C++      +    N+ WLL E VYL  LLA +  S +  F   V  GWG
Sbjct: 216 GLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWG 275

Query: 252 LPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKL 311
           +P+LF   W   K  +ED  CW  +    YW II+ PI+ ++GVNF +F+ +I I+V KL
Sbjct: 276 VPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKL 335

Query: 312 E 312
           +
Sbjct: 336 K 336


>gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]
          Length = 550

 Score =  165 bits (417), Expect = 6e-41
 Identities = 95/301 (31%), Positives = 145/301 (48%), Gaps = 36/301 (11%)

Query: 55  CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITG-----------WSE 103
           C   WDGL+CWP    G+   +PCP +   F+ + G   R C   G           W+ 
Sbjct: 63  CFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHK-GVAFRHCNPNGTWDFMHSLNKTWAN 121

Query: 104 PFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNY 163
                    P   ++   ++ +F  + ++YTVG+SIS  +L VAI I+   RRLHC RNY
Sbjct: 122 YSDCLRFLQP---DISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNY 178

Query: 164 VHTQLFTTFILKAGAVFLKD------------AALFHSDDTDHCSFST-------VLCKV 204
           +H  LF +F+L+A ++F+KD             +L   DD  +   +T       + CK+
Sbjct: 179 IHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKI 238

Query: 205 SVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCK 264
           +V    +   TN+ W+L E +YL+ L+     S  +  W  +L GWG P  F   W   +
Sbjct: 239 AVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVAR 298

Query: 265 LAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLH-TQSQ 323
               D  CW+L       WI + PI+ ++G+NF LFLN +R+L  K+       H T+ Q
Sbjct: 299 ATLADARCWEL-SAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQ 357

Query: 324 Y 324
           Y
Sbjct: 358 Y 358


>gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]
          Length = 466

 Score =  164 bits (414), Expect = 1e-40
 Identities = 93/289 (32%), Positives = 145/289 (50%), Gaps = 10/289 (3%)

Query: 35  REDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFS-HFSSESGAVK 93
           R +    L AAE  P + L C  ++D  +CW  A         CP +   H    +G V 
Sbjct: 43  RRECQETLAAAE--PPSGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVL 100

Query: 94  RDCTITG-WSEPFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILV 152
           R C   G W           P   E   ++      ++++YTVG+S+S+  L +A+ IL 
Sbjct: 101 RQCGSDGQWGLWRDHTQCENPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILS 160

Query: 153 ALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALF----HSDDTDHCSFSTVL--CKVSV 206
             RRLHC RNY+H  LFT+F+L+A A+  +D  L     +  D     ++  L  C+ + 
Sbjct: 161 LFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQ 220

Query: 207 AASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLA 266
             + +    N++WLL E VYL+ LL     S    F + +L GWG P LF   WV  +  
Sbjct: 221 IVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYL 280

Query: 267 FEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQ 315
           +E+  CW+ ++    WWII+ PI++++ +NF +F+ I+ IL+ KL   Q
Sbjct: 281 YENTQCWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQ 329


>gi|4503947 glucagon receptor [Homo sapiens]
          Length = 477

 Score =  160 bits (406), Expect = 1e-39
 Identities = 94/286 (32%), Positives = 146/286 (51%), Gaps = 19/286 (6%)

Query: 49  PNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFS-HFSSESGAVKRDCTITGWSEPFP- 106
           P T L C  T+D   CWP   +     + CP +   H   +   V + C   G     P 
Sbjct: 52  PPTELVCNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPR 111

Query: 107 --PYPVA--CPVP---LELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHC 159
             P+  A  C +    +E+  E    +S+ +++YTVG+S+S+ AL +A+ IL  L +LHC
Sbjct: 112 GQPWRDASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHC 171

Query: 160 PRNYVHTQLFTTFILKAGAVFLKDAAL---FHSDDTDHCSFSTVL-------CKVSVAAS 209
            RN +H  LF +F+LKA +V + D  L   +     D  S ST L       C+V+    
Sbjct: 172 TRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFM 231

Query: 210 HFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFED 269
            +  + N+ WLL E +YL+ LL   +   R  F   +  GWG P+LF   W   K  FE+
Sbjct: 232 QYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFEN 291

Query: 270 IACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQ 315
           + CW  +D   +WWI++ P+ L++ +NF +F+ I+++LV KL   Q
Sbjct: 292 VQCWTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQ 337


>gi|223717985 corticotropin releasing hormone receptor 1 isoform 4
           [Homo sapiens]
          Length = 401

 Score =  125 bits (313), Expect = 7e-29
 Identities = 83/274 (30%), Positives = 130/274 (47%), Gaps = 20/274 (7%)

Query: 53  LGCPATWDGL-LCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA 111
           L C A+ D +  CWP + +G+ V  PCP FF         V+ + T  G+ E       A
Sbjct: 42  LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFY-------GVRYNTTNNGYRECLANGSWA 94

Query: 112 CPVPL----ELLAEEES---YFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYV 164
             V      E+L EE+    ++    II  +GH IS+VAL VA  + + LR + C RN +
Sbjct: 95  ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNII 154

Query: 165 HTQLFTTFILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEA 224
           H  L + FIL+    F+    +       +  +    C++  AA ++  +TNF W+  E 
Sbjct: 155 HWNLISAFILRNATWFVVQLTMSPEVHQSNVGW----CRLVTAAYNYFHVTNFFWMFGEG 210

Query: 225 VYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYW-W 283
            YL+  +  T  + R   W  +  GWG+P      W   KL +++  CW       Y  +
Sbjct: 211 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDY 270

Query: 284 IIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGS 317
           I +GP++L + +NF    NI+RIL+ KL  +  S
Sbjct: 271 IYQGPMILVLLINFIFLFNIVRILMTKLRASTTS 304


>gi|19923245 corticotropin releasing hormone receptor 1 isoform 2
           [Homo sapiens]
          Length = 415

 Score =  125 bits (313), Expect = 7e-29
 Identities = 83/274 (30%), Positives = 130/274 (47%), Gaps = 20/274 (7%)

Query: 53  LGCPATWDGL-LCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA 111
           L C A+ D +  CWP + +G+ V  PCP FF         V+ + T  G+ E       A
Sbjct: 42  LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFY-------GVRYNTTNNGYRECLANGSWA 94

Query: 112 CPVPL----ELLAEEES---YFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYV 164
             V      E+L EE+    ++    II  +GH IS+VAL VA  + + LR + C RN +
Sbjct: 95  ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNII 154

Query: 165 HTQLFTTFILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEA 224
           H  L + FIL+    F+    +       +  +    C++  AA ++  +TNF W+  E 
Sbjct: 155 HWNLISAFILRNATWFVVQLTMSPEVHQSNVGW----CRLVTAAYNYFHVTNFFWMFGEG 210

Query: 225 VYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYW-W 283
            YL+  +  T  + R   W  +  GWG+P      W   KL +++  CW       Y  +
Sbjct: 211 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDY 270

Query: 284 IIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGS 317
           I +GP++L + +NF    NI+RIL+ KL  +  S
Sbjct: 271 IYQGPMILVLLINFIFLFNIVRILMTKLRASTTS 304


>gi|32307159 corticotropin releasing hormone receptor 2 [Homo
           sapiens]
          Length = 411

 Score =  119 bits (298), Expect = 4e-27
 Identities = 77/271 (28%), Positives = 124/271 (45%), Gaps = 18/271 (6%)

Query: 55  CPATWDGL-LCWPTAGSGEWVTLPCPDFFSHFS-SESGAVKRDCTITGWSEPFPPYPVAC 112
           C  T D +  CWP + +G  V  PCP++F+    + +    R+C   G       Y    
Sbjct: 40  CNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCE 99

Query: 113 PVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTF 172
           P+  +   + + ++    ++  +GH +S+ AL  A  + +ALR + C RN +H  L TTF
Sbjct: 100 PILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTF 159

Query: 173 ILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLA 232
           IL+    FL         D +    + V C+      ++  +TNF W+  E  YL+  + 
Sbjct: 160 ILRNVMWFLLQLV-----DHEVHESNEVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIV 214

Query: 233 STSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACW------DLDDTSPYWWIIK 286
            T  + R      +  GW +P      W   KL +E+  CW      DL D     +I +
Sbjct: 215 MTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFGKEPGDLVD-----YIYQ 269

Query: 287 GPIVLSVGVNFGLFLNIIRILVRKLEPAQGS 317
           GPI+L + +NF    NI+RIL+ KL  +  S
Sbjct: 270 GPIILVLLINFVFLFNIVRILMTKLRASTTS 300


>gi|4502547 calcitonin receptor [Homo sapiens]
          Length = 474

 Score =  109 bits (273), Expect = 3e-24
 Identities = 75/264 (28%), Positives = 122/264 (46%), Gaps = 15/264 (5%)

Query: 55  CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITG-W------SEPFPP 107
           C  TWDG LCW    +G      CPD+F  F   S  V + C   G W      +  +  
Sbjct: 72  CNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDP-SEKVTKYCDEKGVWFKHPENNRTWSN 130

Query: 108 YPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQ 167
           Y +      E L  + +Y   +  +  VGHS+SI  L +++ I V  R L C R  +H  
Sbjct: 131 YTMCNAFTPEKL--KNAY--VLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKN 186

Query: 168 LFTTFILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL 227
           +F T+IL +  + +    +  + +        V CK+      +    N+ W+L E +YL
Sbjct: 187 MFLTYILNSMIIIIHLVEVVPNGEL--VRRDPVSCKILHFFHQYMMACNYFWMLCEGIYL 244

Query: 228 NCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKG 287
           + L+     + ++   W  L GWG P++ T      +  + +  CW L   +   +II G
Sbjct: 245 HTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCW-LSVETHLLYIIHG 303

Query: 288 PIVLSVGVNFGLFLNIIRILVRKL 311
           P++ ++ VNF   LNI+R+LV K+
Sbjct: 304 PVMAALVVNFFFLLNIVRVLVTKM 327


>gi|223717971 corticotropin releasing hormone receptor 1 isoform 1
           [Homo sapiens]
          Length = 444

 Score =  109 bits (273), Expect = 3e-24
 Identities = 83/303 (27%), Positives = 130/303 (42%), Gaps = 49/303 (16%)

Query: 53  LGCPATWDGL-LCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA 111
           L C A+ D +  CWP + +G+ V  PCP FF         V+ + T  G+ E       A
Sbjct: 42  LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFY-------GVRYNTTNNGYRECLANGSWA 94

Query: 112 CPVPL----ELLAEEES---YFSTVKIIYTVGHSISIVALFVAITILVALR--------- 155
             V      E+L EE+    ++    II  +GH IS+VAL VA  + + LR         
Sbjct: 95  ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQ 154

Query: 156 --------------------RLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDTDHC 195
                                + C RN +H  L + FIL+    F+    +       + 
Sbjct: 155 ADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEVHQSNV 214

Query: 196 SFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVL 255
            +    C++  AA ++  +TNF W+  E  YL+  +  T  + R   W  +  GWG+P  
Sbjct: 215 GW----CRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFP 270

Query: 256 FTGTWVSCKLAFEDIACWDLDDTSPYW-WIIKGPIVLSVGVNFGLFLNIIRILVRKLEPA 314
               W   KL +++  CW       Y  +I +GP++L + +NF    NI+RIL+ KL  +
Sbjct: 271 IIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRAS 330

Query: 315 QGS 317
             S
Sbjct: 331 TTS 333


>gi|223717978 corticotropin releasing hormone receptor 1 isoform 3
           [Homo sapiens]
          Length = 375

 Score =  108 bits (271), Expect = 5e-24
 Identities = 63/205 (30%), Positives = 102/205 (49%), Gaps = 8/205 (3%)

Query: 117 ELLAEEES---YFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFI 173
           E+L EE+    ++    II  +GH IS+VAL VA  + + LR + C RN +H  L + FI
Sbjct: 64  EILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFI 123

Query: 174 LKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLAS 233
           L+    F+    +       +  +    C++  AA ++  +TNF W+  E  YL+  +  
Sbjct: 124 LRNATWFVVQLTMSPEVHQSNVGW----CRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVL 179

Query: 234 TSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYW-WIIKGPIVLS 292
           T  + R   W  +  GWG+P      W   KL +++  CW       Y  +I +GP++L 
Sbjct: 180 TYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILV 239

Query: 293 VGVNFGLFLNIIRILVRKLEPAQGS 317
           + +NF    NI+RIL+ KL  +  S
Sbjct: 240 LLINFIFLFNIVRILMTKLRASTTS 264


>gi|5031621 calcitonin receptor-like [Homo sapiens]
          Length = 461

 Score =  105 bits (263), Expect = 4e-23
 Identities = 70/261 (26%), Positives = 115/261 (44%), Gaps = 7/261 (2%)

Query: 55  CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITG-WSEPFPPYPVACP 113
           C  TWDG LCW    +G      CPD+F  F   S  V + C   G W            
Sbjct: 65  CNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDP-SEKVTKICDQDGNWFRHPASNRTWTN 123

Query: 114 VPLELLAEEESYFSTVKIIYT--VGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTT 171
                +   E   + + + Y   +GH +SI +L +++ I    + L C R  +H  LF +
Sbjct: 124 YTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFS 183

Query: 172 FILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLL 231
           F+  +    +   A+ ++      + + V CKVS     +    N+ W+L E +YL+ L+
Sbjct: 184 FVCNSVVTIIHLTAVANNQAL--VATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLI 241

Query: 232 ASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVL 291
                + ++   W    GWG P++        +  + +  CW   DT    +II GPI  
Sbjct: 242 VVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTH-LLYIIHGPICA 300

Query: 292 SVGVNFGLFLNIIRILVRKLE 312
           ++ VN    LNI+R+L+ KL+
Sbjct: 301 ALLVNLFFLLNIVRVLITKLK 321


>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
           sapiens]
          Length = 652

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 56/214 (26%), Positives = 88/214 (41%), Gaps = 20/214 (9%)

Query: 114 VPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFI 173
           V + L ++EE    TV  I  VG S+S++ L +A    +  + +      +H QL     
Sbjct: 343 VLMALTSQEEDPVLTV--ITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLF 400

Query: 174 LKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL-----N 228
           L A  +FL        D T+      VLC +   A H+  +  F+W+L E V+L     N
Sbjct: 401 L-AHLLFLVGI-----DRTE----PKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARN 450

Query: 229 CLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIA--CWDLDDTSPYWWIIK 286
             + + S  +R   W +   G+G+P +      +        A  CW L     + W   
Sbjct: 451 LTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCW-LHLDQGFMWSFL 509

Query: 287 GPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHT 320
           GP+      N  LF+ +  IL RKL      + T
Sbjct: 510 GPVCAIFSANLVLFILVFWILKRKLSSLNSEVST 543


>gi|163792198 latrophilin 3 precursor [Homo sapiens]
          Length = 1469

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 55/179 (30%), Positives = 79/179 (44%), Gaps = 22/179 (12%)

Query: 131  IIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSD 190
            +I  VG  +S+V L + I      R L   RN +H  L  +  + A  +FL        +
Sbjct: 879  VITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFV-AELLFL-----IGIN 932

Query: 191  DTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLAST--SPSSRRAFWWLVLA 248
             TD      + C V  A  HF  +  F+W+  E V L  +L     S  SRR +++LV  
Sbjct: 933  RTDQ----PIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLV-- 986

Query: 249  GWGLPVLFTGTWVSCKLAFE----DIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNI 303
            G+G+P L     VS  + +     D  CW   DT   W  I GP  L + +N  +FL I
Sbjct: 987  GYGMPALIVA--VSAAVDYRSYGTDKVCWLRLDTYFIWSFI-GPATLIIMLNV-IFLGI 1041


>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
          Length = 1474

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 52/199 (26%), Positives = 79/199 (39%), Gaps = 18/199 (9%)

Query: 118  LLAEEESYFSTVK-----IIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTF 172
            L+A  E Y   +      +I  VG  IS+V L + I+    LR L   RN +H  L    
Sbjct: 844  LMAHREIYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINL 903

Query: 173  ILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLA 232
             L A  +FL        D T +     + C +     H+  +  FSWL  E V+L  LL 
Sbjct: 904  FL-AELLFLVGI-----DKTQY----EIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLV 953

Query: 233  STSPSSRRAFWWLVLAGWGLPVLFTG--TWVSCKLAFEDIACWDLDDTSPYWWIIKGPIV 290
                S      +  L G+  P L  G    +  +    + ACW L   + + W   GP+ 
Sbjct: 954  EVFESEYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACW-LRVDNYFIWSFIGPVS 1012

Query: 291  LSVGVNFGLFLNIIRILVR 309
              + VN    +  +  ++R
Sbjct: 1013 FVIVVNLVFLMVTLHKMIR 1031


>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
          Length = 1469

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 52/199 (26%), Positives = 79/199 (39%), Gaps = 18/199 (9%)

Query: 118  LLAEEESYFSTVK-----IIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTF 172
            L+A  E Y   +      +I  VG  IS+V L + I+    LR L   RN +H  L    
Sbjct: 839  LMAHREIYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINL 898

Query: 173  ILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLA 232
             L A  +FL        D T +     + C +     H+  +  FSWL  E V+L  LL 
Sbjct: 899  FL-AELLFLVGI-----DKTQY----EIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLV 948

Query: 233  STSPSSRRAFWWLVLAGWGLPVLFTG--TWVSCKLAFEDIACWDLDDTSPYWWIIKGPIV 290
                S      +  L G+  P L  G    +  +    + ACW L   + + W   GP+ 
Sbjct: 949  EVFESEYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACW-LRVDNYFIWSFIGPVS 1007

Query: 291  LSVGVNFGLFLNIIRILVR 309
              + VN    +  +  ++R
Sbjct: 1008 FVIVVNLVFLMVTLHKMIR 1026


>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
            sapiens]
          Length = 3014

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 46/186 (24%), Positives = 73/186 (39%), Gaps = 15/186 (8%)

Query: 114  VPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFI 173
            V +++   E      +KI+     S+S+ AL VA  +L  +R L    + +H  L     
Sbjct: 2453 VLMDISRRENGEVLPLKIVTYAAVSLSLAALLVAFVLLSLVRMLRSNLHSIHKHL----- 2507

Query: 174  LKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLAS 233
              A A+FL         +     F   LC V     H+  M+ F+W L E++++  +L  
Sbjct: 2508 --AVALFLSQLVFVIGINQTENPF---LCTVVAILLHYIYMSTFAWTLVESLHVYRMLTE 2562

Query: 234  TSPSSRRAFWWLVLAGWGLPVLFTGTWVSCK---LAFEDIACWDLDDTSPYWWIIKGPIV 290
                      +  + GWG+P + TG  V          D     L DT    W   GPI 
Sbjct: 2563 VRNIDTGPMRFYYVVGWGIPAIVTGLAVGLDPQGYGNPDFCWLSLQDT--LIWSFAGPIG 2620

Query: 291  LSVGVN 296
              + +N
Sbjct: 2621 AVIIIN 2626



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 15/51 (29%), Positives = 21/51 (41%), Gaps = 5/51 (9%)

Query: 54   GCPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEP 104
            GCP  ++  + WP    G+   +PCP       S   AV+      GW  P
Sbjct: 2054 GCPKAFEAGIWWPQTKFGQPAAVPCPK-----GSVGNAVRHCSGEKGWLPP 2099


>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
          Length = 874

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 44/198 (22%), Positives = 80/198 (40%), Gaps = 17/198 (8%)

Query: 114 VPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFI 173
           VPLEL    +   S++  +      + +VA  V   +L ++  +   R ++H  L     
Sbjct: 554 VPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANL----- 608

Query: 174 LKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLAS 233
             + AV +    L  S   +     T  C+V     H+  ++ F+W+L E ++L  ++  
Sbjct: 609 --SFAVLVAQVLLLISFRLEP---GTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIK 663

Query: 234 TSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIA----CWDLDDTSPYWWIIKGPI 289
              S      +    GWG P+L     +S   A +       CW L   S   W    P 
Sbjct: 664 VFGSEDSKHRYYYGMGWGFPLLI--CIISLSFAMDSYGTSNNCW-LSLASGAIWAFVAPA 720

Query: 290 VLSVGVNFGLFLNIIRIL 307
           +  + VN G+ + + R++
Sbjct: 721 LFVIVVNIGILIAVTRVI 738


>gi|23397681 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform a [Homo sapiens]
          Length = 823

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 60/259 (23%), Positives = 99/259 (38%), Gaps = 33/259 (12%)

Query: 69  GSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFST 128
           G G W T  C    +    ++  + R   ++ ++     Y V          +EE    T
Sbjct: 491 GCGHWATTGCSTIGTR---DTSTICRCTHLSSFAVLMAHYDV----------QEEDPVLT 537

Query: 129 VKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFH 188
           V  I  +G S+S++ L +A    +  + +      +H QL     L A  +FL       
Sbjct: 538 V--ITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFL-AHLLFLVAI---- 590

Query: 189 SDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL-----NCLLASTSPSSRRAFW 243
            D T H     VLC +     H+  +   +W+L EA+YL     N  + + S  +R    
Sbjct: 591 -DQTGH----KVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKK 645

Query: 244 WLVLAGWGLPVLFTGTWVSCK--LAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFL 301
            +   G+G+P +      + +  L      CW L     + W   GP+     VN  LFL
Sbjct: 646 LMFPVGYGVPAVTVAISAASRPHLYGTPSRCW-LQPEKGFIWGFLGPVCAIFSVNLVLFL 704

Query: 302 NIIRILVRKLEPAQGSLHT 320
             + IL  +L      + T
Sbjct: 705 VTLWILKNRLSSLNSEVST 723


>gi|23397693 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform g [Homo sapiens]
          Length = 719

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 60/259 (23%), Positives = 99/259 (38%), Gaps = 33/259 (12%)

Query: 69  GSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFST 128
           G G W T  C    +    ++  + R   ++ ++     Y V          +EE    T
Sbjct: 387 GCGHWATTGCSTIGTR---DTSTICRCTHLSSFAVLMAHYDV----------QEEDPVLT 433

Query: 129 VKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFH 188
           V  I  +G S+S++ L +A    +  + +      +H QL     L A  +FL       
Sbjct: 434 V--ITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFL-AHLLFLVAI---- 486

Query: 189 SDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL-----NCLLASTSPSSRRAFW 243
            D T H     VLC +     H+  +   +W+L EA+YL     N  + + S  +R    
Sbjct: 487 -DQTGH----KVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKK 541

Query: 244 WLVLAGWGLPVLFTGTWVSCK--LAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFL 301
            +   G+G+P +      + +  L      CW L     + W   GP+     VN  LFL
Sbjct: 542 LMFPVGYGVPAVTVAISAASRPHLYGTPSRCW-LQPEKGFIWGFLGPVCAIFSVNLVLFL 600

Query: 302 NIIRILVRKLEPAQGSLHT 320
             + IL  +L      + T
Sbjct: 601 VTLWILKNRLSSLNSEVST 619


>gi|23397691 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform f [Homo sapiens]
          Length = 763

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 60/259 (23%), Positives = 99/259 (38%), Gaps = 33/259 (12%)

Query: 69  GSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFST 128
           G G W T  C    +    ++  + R   ++ ++     Y V          +EE    T
Sbjct: 431 GCGHWATTGCSTIGTR---DTSTICRCTHLSSFAVLMAHYDV----------QEEDPVLT 477

Query: 129 VKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFH 188
           V  I  +G S+S++ L +A    +  + +      +H QL     L A  +FL       
Sbjct: 478 V--ITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFL-AHLLFLVAI---- 530

Query: 189 SDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL-----NCLLASTSPSSRRAFW 243
            D T H     VLC +     H+  +   +W+L EA+YL     N  + + S  +R    
Sbjct: 531 -DQTGH----KVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKK 585

Query: 244 WLVLAGWGLPVLFTGTWVSCK--LAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFL 301
            +   G+G+P +      + +  L      CW L     + W   GP+     VN  LFL
Sbjct: 586 LMFPVGYGVPAVTVAISAASRPHLYGTPSRCW-LQPEKGFIWGFLGPVCAIFSVNLVLFL 644

Query: 302 NIIRILVRKLEPAQGSLHT 320
             + IL  +L      + T
Sbjct: 645 VTLWILKNRLSSLNSEVST 663


>gi|23397689 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform e [Homo sapiens]
          Length = 812

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 60/259 (23%), Positives = 99/259 (38%), Gaps = 33/259 (12%)

Query: 69  GSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFST 128
           G G W T  C    +    ++  + R   ++ ++     Y V          +EE    T
Sbjct: 480 GCGHWATTGCSTIGTR---DTSTICRCTHLSSFAVLMAHYDV----------QEEDPVLT 526

Query: 129 VKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFH 188
           V  I  +G S+S++ L +A    +  + +      +H QL     L A  +FL       
Sbjct: 527 V--ITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFL-AHLLFLVAI---- 579

Query: 189 SDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL-----NCLLASTSPSSRRAFW 243
            D T H     VLC +     H+  +   +W+L EA+YL     N  + + S  +R    
Sbjct: 580 -DQTGH----KVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKK 634

Query: 244 WLVLAGWGLPVLFTGTWVSCK--LAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFL 301
            +   G+G+P +      + +  L      CW L     + W   GP+     VN  LFL
Sbjct: 635 LMFPVGYGVPAVTVAISAASRPHLYGTPSRCW-LQPEKGFIWGFLGPVCAIFSVNLVLFL 693

Query: 302 NIIRILVRKLEPAQGSLHT 320
             + IL  +L      + T
Sbjct: 694 VTLWILKNRLSSLNSEVST 712


>gi|23397687 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform d [Homo sapiens]
          Length = 681

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 60/259 (23%), Positives = 99/259 (38%), Gaps = 33/259 (12%)

Query: 69  GSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFST 128
           G G W T  C    +    ++  + R   ++ ++     Y V          +EE    T
Sbjct: 349 GCGHWATTGCSTIGTR---DTSTICRCTHLSSFAVLMAHYDV----------QEEDPVLT 395

Query: 129 VKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFH 188
           V  I  +G S+S++ L +A    +  + +      +H QL     L A  +FL       
Sbjct: 396 V--ITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFL-AHLLFLVAI---- 448

Query: 189 SDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL-----NCLLASTSPSSRRAFW 243
            D T H     VLC +     H+  +   +W+L EA+YL     N  + + S  +R    
Sbjct: 449 -DQTGH----KVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKK 503

Query: 244 WLVLAGWGLPVLFTGTWVSCK--LAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFL 301
            +   G+G+P +      + +  L      CW L     + W   GP+     VN  LFL
Sbjct: 504 LMFPVGYGVPAVTVAISAASRPHLYGTPSRCW-LQPEKGFIWGFLGPVCAIFSVNLVLFL 562

Query: 302 NIIRILVRKLEPAQGSLHT 320
             + IL  +L      + T
Sbjct: 563 VTLWILKNRLSSLNSEVST 581


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.138    0.472 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,128,964
Number of Sequences: 37866
Number of extensions: 667587
Number of successful extensions: 2081
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 1943
Number of HSP's gapped (non-prelim): 102
length of query: 337
length of database: 18,247,518
effective HSP length: 103
effective length of query: 234
effective length of database: 14,347,320
effective search space: 3357272880
effective search space used: 3357272880
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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