BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|58530853 growth hormone releasing hormone receptor isoform b precursor [Homo sapiens] (337 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|58530853 growth hormone releasing hormone receptor isoform b ... 714 0.0 gi|58530851 growth hormone releasing hormone receptor isoform a ... 688 0.0 gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens] 265 3e-71 gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens] 258 5e-69 gi|114205383 secretin receptor precursor [Homo sapiens] 254 6e-68 gi|29171759 adenylate cyclase activating polypeptide 1 (pituitar... 249 3e-66 gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens] 186 3e-47 gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapi... 176 3e-44 gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens] 167 1e-41 gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens] 165 6e-41 gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens] 164 1e-40 gi|4503947 glucagon receptor [Homo sapiens] 160 1e-39 gi|223717985 corticotropin releasing hormone receptor 1 isoform ... 125 7e-29 gi|19923245 corticotropin releasing hormone receptor 1 isoform 2... 125 7e-29 gi|32307159 corticotropin releasing hormone receptor 2 [Homo sap... 119 4e-27 gi|4502547 calcitonin receptor [Homo sapiens] 109 3e-24 gi|223717971 corticotropin releasing hormone receptor 1 isoform ... 109 3e-24 gi|223717978 corticotropin releasing hormone receptor 1 isoform ... 108 5e-24 gi|5031621 calcitonin receptor-like [Homo sapiens] 105 4e-23 gi|133930786 egf-like module-containing mucin-like receptor 3 [H... 57 2e-08 gi|163792198 latrophilin 3 precursor [Homo sapiens] 57 3e-08 gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens] 56 5e-08 gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens] 56 5e-08 gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s... 54 2e-07 gi|45433552 G protein-coupled receptor 133 [Homo sapiens] 54 2e-07 gi|23397681 egf-like module containing, mucin-like, hormone rece... 52 1e-06 gi|23397693 egf-like module containing, mucin-like, hormone rece... 52 1e-06 gi|23397691 egf-like module containing, mucin-like, hormone rece... 52 1e-06 gi|23397689 egf-like module containing, mucin-like, hormone rece... 52 1e-06 gi|23397687 egf-like module containing, mucin-like, hormone rece... 52 1e-06 >gi|58530853 growth hormone releasing hormone receptor isoform b precursor [Homo sapiens] Length = 337 Score = 714 bits (1844), Expect = 0.0 Identities = 337/337 (100%), Positives = 337/337 (100%) Query: 1 MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD 60 MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD Sbjct: 1 MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD 60 Query: 61 GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA 120 GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA Sbjct: 61 GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA 120 Query: 121 EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF 180 EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF Sbjct: 121 EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF 180 Query: 181 LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR 240 LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR Sbjct: 181 LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR 240 Query: 241 AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF 300 AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF Sbjct: 241 AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF 300 Query: 301 LNIIRILVRKLEPAQGSLHTQSQYWYCVFVSGDTGKG 337 LNIIRILVRKLEPAQGSLHTQSQYWYCVFVSGDTGKG Sbjct: 301 LNIIRILVRKLEPAQGSLHTQSQYWYCVFVSGDTGKG 337 >gi|58530851 growth hormone releasing hormone receptor isoform a precursor [Homo sapiens] Length = 423 Score = 688 bits (1776), Expect = 0.0 Identities = 325/325 (100%), Positives = 325/325 (100%) Query: 1 MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD 60 MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD Sbjct: 1 MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD 60 Query: 61 GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA 120 GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA Sbjct: 61 GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA 120 Query: 121 EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF 180 EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF Sbjct: 121 EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF 180 Query: 181 LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR 240 LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR Sbjct: 181 LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR 240 Query: 241 AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF 300 AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF Sbjct: 241 AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF 300 Query: 301 LNIIRILVRKLEPAQGSLHTQSQYW 325 LNIIRILVRKLEPAQGSLHTQSQYW Sbjct: 301 LNIIRILVRKLEPAQGSLHTQSQYW 325 >gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens] Length = 457 Score = 265 bits (678), Expect = 3e-71 Identities = 134/305 (43%), Positives = 181/305 (59%), Gaps = 7/305 (2%) Query: 14 LSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEW 73 L P + ECD++ + CL+ A+ + N T+GC WD L CWP G+ Sbjct: 23 LGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQ-LENETIGCSKMWDNLTCWPATPRGQV 81 Query: 74 VTLPCPDFFSHFSSESGA-VKRDCTITGWSEPFP-PYPVACPVPLELLAEEES---YFST 128 V L CP F FSS G V R CT GW+ P PYP+AC + + + +E ++ + Sbjct: 82 VVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASLDEQQTMFYGS 141 Query: 129 VKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFH 188 VK YT+G+ +S+ L VA IL R+LHC RNY+H LF +FIL+A AVF+KD ALF Sbjct: 142 VKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFD 201 Query: 189 SDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLA 248 S ++D CS +V CK ++ + M NF WLL E +YL LLA + S R+ FW +L Sbjct: 202 SGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILI 261 Query: 249 GWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILV 308 GWG+P FT W ++ FED CWD ++S WWIIKGPI+ S+ VNF LF+ IIRIL+ Sbjct: 262 GWGVPSTFTMVWTIARIHFEDYGCWDTINSS-LWWIIKGPILTSILVNFILFICIIRILL 320 Query: 309 RKLEP 313 +KL P Sbjct: 321 QKLRP 325 >gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens] Length = 438 Score = 258 bits (659), Expect = 5e-69 Identities = 127/304 (41%), Positives = 181/304 (59%), Gaps = 4/304 (1%) Query: 24 MHPECDFITQLREDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFS 83 +HPEC F +++E+E+ C + C WD + CW A GE VT+PCP FS Sbjct: 21 IHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNITCWRPANVGETVTVPCPKVFS 80 Query: 84 HFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVA 143 +F S++G + ++CT GWSE FP + AC + +++ VK IYT+G+S+S+++ Sbjct: 81 NFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMS 140 Query: 144 LFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDTDHC---SFSTV 200 L IL R+LHC RNY+H LF +FIL+A +V +KD L+ S T HC S V Sbjct: 141 LATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWV 200 Query: 201 LCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTW 260 CK+S+ + M NF WLL E +YL+ LL + P RR F +L GWGLP + G W Sbjct: 201 GCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLP-PRRCFLAYLLIGWGLPTVCIGAW 259 Query: 261 VSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHT 320 + +L ED CWD +D S WW+I+ PI++S+ VNF LF++IIRIL++KL + Sbjct: 260 TAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGND 319 Query: 321 QSQY 324 QSQY Sbjct: 320 QSQY 323 >gi|114205383 secretin receptor precursor [Homo sapiens] Length = 440 Score = 254 bits (650), Expect = 6e-68 Identities = 126/306 (41%), Positives = 178/306 (58%), Gaps = 9/306 (2%) Query: 28 CDFITQLREDESACLQAAEEMPNTTLG-------CPATWDGLLCWPTAGSGEWVTLPCPD 80 CD + L E++ CLQ LG C WD + CWP++ G V + CP Sbjct: 32 CDVLQVLWEEQDQCLQELSREQTGDLGTEQPVPGCEGMWDNISCWPSSVPGRMVEVECPR 91 Query: 81 FFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEE--SYFSTVKIIYTVGHS 138 F +S +G++ R+CT GWSE FP +AC V + + E+ SY +K++YTVG+S Sbjct: 92 FLRMLTSRNGSLFRNCTQDGWSETFPRPNLACGVNVNDSSNEKRHSYLLKLKVMYTVGYS 151 Query: 139 ISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDTDHCSFS 198 S+V L VA+ IL A RRLHC RNY+H LF +FIL+A + F+KDA LF SDD +C Sbjct: 152 SSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAH 211 Query: 199 TVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTG 258 CK+ + + M N+SWLL E +YL+ LLA + S R+ V GWG P +F Sbjct: 212 RAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVA 271 Query: 259 TWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSL 318 W + ED+ CWD++ + WWII+GP++LS+ +NF LF+NI+RIL+RKL + Sbjct: 272 LWAIARHFLEDVGCWDINANASIWWIIRGPVILSILINFILFINILRILMRKLRTQETRG 331 Query: 319 HTQSQY 324 + S Y Sbjct: 332 NEVSHY 337 >gi|29171759 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I precursor [Homo sapiens] Length = 468 Score = 249 bits (635), Expect = 3e-66 Identities = 125/320 (39%), Positives = 183/320 (57%), Gaps = 35/320 (10%) Query: 24 MHPECDFITQLREDESACL---QAAEEMP---NTTLGCPATWDGLLCWPTAGSGEWVTLP 77 MH +C F +++++ CL Q A E+ +++ GCP WD + CW A GE V + Sbjct: 21 MHSDCIF----KKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVLVS 76 Query: 78 CPDFFSHFS-----------------------SESGAVKRDCTITGWSEPFPPYPVACPV 114 CP+ F F+ S+ G V R+CT GWSEPFP Y AC Sbjct: 77 CPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGF 136 Query: 115 PL--ELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTF 172 +++ Y+ +VK +YTVG+S S+V L A+ IL R+LHC RN++H LF +F Sbjct: 137 DEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSF 196 Query: 173 ILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLA 232 +L+A +VF+KD L+ D++HC STV CK + H+ ++N+ WL E +YL LL Sbjct: 197 MLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLV 256 Query: 233 STSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLS 292 T RR F+W + GWG P + W + +L F+D CWD++D++ WW+IKGP+V S Sbjct: 257 ETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGS 316 Query: 293 VGVNFGLFLNIIRILVRKLE 312 + VNF LF+ II ILV+KL+ Sbjct: 317 IMVNFVLFIGIIVILVQKLQ 336 >gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens] Length = 593 Score = 186 bits (471), Expect = 3e-47 Identities = 105/298 (35%), Positives = 150/298 (50%), Gaps = 30/298 (10%) Query: 55 CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA--- 111 C WD +LCWP GE V +PCPD+ F+ + A +R C G E P + Sbjct: 108 CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRR-CDRNGSWELVPGHNRTWAN 166 Query: 112 ---CPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQL 168 C L E F + +IYTVG+S+S+ +L VA+ IL RRLHC RNY+H L Sbjct: 167 YSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHL 226 Query: 169 FTTFILKAGAVFLKDAALFHSDDTDHCSFST---------------------VLCKVSVA 207 F +F+L+A ++F+KDA L+ D T C+V+V Sbjct: 227 FLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVT 286 Query: 208 ASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAF 267 + TN+ W+L E +YL+ L+ S ++ W + GWGLP +F WVS + Sbjct: 287 FFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATL 346 Query: 268 EDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKL-EPAQGSLHTQSQY 324 + CWDL + WII+ PI+ S+ +NF LF+NI+R+L KL E G T+ QY Sbjct: 347 ANTGCWDLSSGNKK-WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQY 403 >gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapiens] Length = 553 Score = 176 bits (446), Expect = 3e-44 Identities = 101/296 (34%), Positives = 154/296 (52%), Gaps = 20/296 (6%) Query: 38 ESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSES-GAVKRDC 96 + ACL+ + P+ C T+D +CWP + G V++PCP + +S ES G R C Sbjct: 80 KQACLRDLLKEPSGIF-CNGTFDQYVCWPHSSPGN-VSVPCPSYLPWWSEESSGRAYRHC 137 Query: 97 TITG-WSEPFPPYPV-----ACPVPLELLAEEESY--FSTVKIIYTVGHSISIVALFVAI 148 G W + C + Y ST++++YTVG+S S+++LF+A+ Sbjct: 138 LAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLAL 197 Query: 149 TILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDT---------DHCSFST 199 T+L+ LR+LHC RNY+H LF +FIL+ AV +KD ++S + S + Sbjct: 198 TLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMS 257 Query: 200 VLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGT 259 C+ H+ N+ WLL E +YL+ LL T RR + +L GW PVLF Sbjct: 258 TSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVP 317 Query: 260 WVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQ 315 W + E+ CW + WWII+GP++L V VNF +FL I+++L+ KL+ Q Sbjct: 318 WGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQ 373 >gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens] Length = 463 Score = 167 bits (423), Expect = 1e-41 Identities = 107/301 (35%), Positives = 150/301 (49%), Gaps = 19/301 (6%) Query: 31 ITQLREDESACLQAAEE--MPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSS- 87 + + RE C ++ E P T L C T+D CWP G +V + CP + SS Sbjct: 36 VQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSV 95 Query: 88 ESGAVKRDCTITG-W------SEPFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSIS 140 G V R CT G W S P+ + E + IIYTVG+++S Sbjct: 96 PQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALS 155 Query: 141 IVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAAL--FHSDDTDHCSFS 198 AL +A IL+ R LHC RNY+H LF +FIL+A +VF+KDAAL +S + Sbjct: 156 FSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWD 215 Query: 199 TVL-------CKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWG 251 +L C++ + N+ WLL E VYL LLA + S + F V GWG Sbjct: 216 GLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWG 275 Query: 252 LPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKL 311 +P+LF W K +ED CW + YW II+ PI+ ++GVNF +F+ +I I+V KL Sbjct: 276 VPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKL 335 Query: 312 E 312 + Sbjct: 336 K 336 >gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens] Length = 550 Score = 165 bits (417), Expect = 6e-41 Identities = 95/301 (31%), Positives = 145/301 (48%), Gaps = 36/301 (11%) Query: 55 CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITG-----------WSE 103 C WDGL+CWP G+ +PCP + F+ + G R C G W+ Sbjct: 63 CFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHK-GVAFRHCNPNGTWDFMHSLNKTWAN 121 Query: 104 PFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNY 163 P ++ ++ +F + ++YTVG+SIS +L VAI I+ RRLHC RNY Sbjct: 122 YSDCLRFLQP---DISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNY 178 Query: 164 VHTQLFTTFILKAGAVFLKD------------AALFHSDDTDHCSFST-------VLCKV 204 +H LF +F+L+A ++F+KD +L DD + +T + CK+ Sbjct: 179 IHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKI 238 Query: 205 SVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCK 264 +V + TN+ W+L E +YL+ L+ S + W +L GWG P F W + Sbjct: 239 AVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVAR 298 Query: 265 LAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLH-TQSQ 323 D CW+L WI + PI+ ++G+NF LFLN +R+L K+ H T+ Q Sbjct: 299 ATLADARCWEL-SAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQ 357 Query: 324 Y 324 Y Sbjct: 358 Y 358 >gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens] Length = 466 Score = 164 bits (414), Expect = 1e-40 Identities = 93/289 (32%), Positives = 145/289 (50%), Gaps = 10/289 (3%) Query: 35 REDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFS-HFSSESGAVK 93 R + L AAE P + L C ++D +CW A CP + H +G V Sbjct: 43 RRECQETLAAAE--PPSGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVL 100 Query: 94 RDCTITG-WSEPFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILV 152 R C G W P E ++ ++++YTVG+S+S+ L +A+ IL Sbjct: 101 RQCGSDGQWGLWRDHTQCENPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILS 160 Query: 153 ALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALF----HSDDTDHCSFSTVL--CKVSV 206 RRLHC RNY+H LFT+F+L+A A+ +D L + D ++ L C+ + Sbjct: 161 LFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQ 220 Query: 207 AASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLA 266 + + N++WLL E VYL+ LL S F + +L GWG P LF WV + Sbjct: 221 IVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYL 280 Query: 267 FEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQ 315 +E+ CW+ ++ WWII+ PI++++ +NF +F+ I+ IL+ KL Q Sbjct: 281 YENTQCWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQ 329 >gi|4503947 glucagon receptor [Homo sapiens] Length = 477 Score = 160 bits (406), Expect = 1e-39 Identities = 94/286 (32%), Positives = 146/286 (51%), Gaps = 19/286 (6%) Query: 49 PNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFS-HFSSESGAVKRDCTITGWSEPFP- 106 P T L C T+D CWP + + CP + H + V + C G P Sbjct: 52 PPTELVCNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPR 111 Query: 107 --PYPVA--CPVP---LELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHC 159 P+ A C + +E+ E +S+ +++YTVG+S+S+ AL +A+ IL L +LHC Sbjct: 112 GQPWRDASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHC 171 Query: 160 PRNYVHTQLFTTFILKAGAVFLKDAAL---FHSDDTDHCSFSTVL-------CKVSVAAS 209 RN +H LF +F+LKA +V + D L + D S ST L C+V+ Sbjct: 172 TRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFM 231 Query: 210 HFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFED 269 + + N+ WLL E +YL+ LL + R F + GWG P+LF W K FE+ Sbjct: 232 QYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFEN 291 Query: 270 IACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQ 315 + CW +D +WWI++ P+ L++ +NF +F+ I+++LV KL Q Sbjct: 292 VQCWTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQ 337 >gi|223717985 corticotropin releasing hormone receptor 1 isoform 4 [Homo sapiens] Length = 401 Score = 125 bits (313), Expect = 7e-29 Identities = 83/274 (30%), Positives = 130/274 (47%), Gaps = 20/274 (7%) Query: 53 LGCPATWDGL-LCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA 111 L C A+ D + CWP + +G+ V PCP FF V+ + T G+ E A Sbjct: 42 LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFY-------GVRYNTTNNGYRECLANGSWA 94 Query: 112 CPVPL----ELLAEEES---YFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYV 164 V E+L EE+ ++ II +GH IS+VAL VA + + LR + C RN + Sbjct: 95 ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNII 154 Query: 165 HTQLFTTFILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEA 224 H L + FIL+ F+ + + + C++ AA ++ +TNF W+ E Sbjct: 155 HWNLISAFILRNATWFVVQLTMSPEVHQSNVGW----CRLVTAAYNYFHVTNFFWMFGEG 210 Query: 225 VYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYW-W 283 YL+ + T + R W + GWG+P W KL +++ CW Y + Sbjct: 211 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDY 270 Query: 284 IIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGS 317 I +GP++L + +NF NI+RIL+ KL + S Sbjct: 271 IYQGPMILVLLINFIFLFNIVRILMTKLRASTTS 304 >gi|19923245 corticotropin releasing hormone receptor 1 isoform 2 [Homo sapiens] Length = 415 Score = 125 bits (313), Expect = 7e-29 Identities = 83/274 (30%), Positives = 130/274 (47%), Gaps = 20/274 (7%) Query: 53 LGCPATWDGL-LCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA 111 L C A+ D + CWP + +G+ V PCP FF V+ + T G+ E A Sbjct: 42 LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFY-------GVRYNTTNNGYRECLANGSWA 94 Query: 112 CPVPL----ELLAEEES---YFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYV 164 V E+L EE+ ++ II +GH IS+VAL VA + + LR + C RN + Sbjct: 95 ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNII 154 Query: 165 HTQLFTTFILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEA 224 H L + FIL+ F+ + + + C++ AA ++ +TNF W+ E Sbjct: 155 HWNLISAFILRNATWFVVQLTMSPEVHQSNVGW----CRLVTAAYNYFHVTNFFWMFGEG 210 Query: 225 VYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYW-W 283 YL+ + T + R W + GWG+P W KL +++ CW Y + Sbjct: 211 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDY 270 Query: 284 IIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGS 317 I +GP++L + +NF NI+RIL+ KL + S Sbjct: 271 IYQGPMILVLLINFIFLFNIVRILMTKLRASTTS 304 >gi|32307159 corticotropin releasing hormone receptor 2 [Homo sapiens] Length = 411 Score = 119 bits (298), Expect = 4e-27 Identities = 77/271 (28%), Positives = 124/271 (45%), Gaps = 18/271 (6%) Query: 55 CPATWDGL-LCWPTAGSGEWVTLPCPDFFSHFS-SESGAVKRDCTITGWSEPFPPYPVAC 112 C T D + CWP + +G V PCP++F+ + + R+C G Y Sbjct: 40 CNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCE 99 Query: 113 PVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTF 172 P+ + + + ++ ++ +GH +S+ AL A + +ALR + C RN +H L TTF Sbjct: 100 PILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTF 159 Query: 173 ILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLA 232 IL+ FL D + + V C+ ++ +TNF W+ E YL+ + Sbjct: 160 ILRNVMWFLLQLV-----DHEVHESNEVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIV 214 Query: 233 STSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACW------DLDDTSPYWWIIK 286 T + R + GW +P W KL +E+ CW DL D +I + Sbjct: 215 MTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFGKEPGDLVD-----YIYQ 269 Query: 287 GPIVLSVGVNFGLFLNIIRILVRKLEPAQGS 317 GPI+L + +NF NI+RIL+ KL + S Sbjct: 270 GPIILVLLINFVFLFNIVRILMTKLRASTTS 300 >gi|4502547 calcitonin receptor [Homo sapiens] Length = 474 Score = 109 bits (273), Expect = 3e-24 Identities = 75/264 (28%), Positives = 122/264 (46%), Gaps = 15/264 (5%) Query: 55 CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITG-W------SEPFPP 107 C TWDG LCW +G CPD+F F S V + C G W + + Sbjct: 72 CNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDP-SEKVTKYCDEKGVWFKHPENNRTWSN 130 Query: 108 YPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQ 167 Y + E L + +Y + + VGHS+SI L +++ I V R L C R +H Sbjct: 131 YTMCNAFTPEKL--KNAY--VLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKN 186 Query: 168 LFTTFILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL 227 +F T+IL + + + + + + V CK+ + N+ W+L E +YL Sbjct: 187 MFLTYILNSMIIIIHLVEVVPNGEL--VRRDPVSCKILHFFHQYMMACNYFWMLCEGIYL 244 Query: 228 NCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKG 287 + L+ + ++ W L GWG P++ T + + + CW L + +II G Sbjct: 245 HTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCW-LSVETHLLYIIHG 303 Query: 288 PIVLSVGVNFGLFLNIIRILVRKL 311 P++ ++ VNF LNI+R+LV K+ Sbjct: 304 PVMAALVVNFFFLLNIVRVLVTKM 327 >gi|223717971 corticotropin releasing hormone receptor 1 isoform 1 [Homo sapiens] Length = 444 Score = 109 bits (273), Expect = 3e-24 Identities = 83/303 (27%), Positives = 130/303 (42%), Gaps = 49/303 (16%) Query: 53 LGCPATWDGL-LCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA 111 L C A+ D + CWP + +G+ V PCP FF V+ + T G+ E A Sbjct: 42 LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFY-------GVRYNTTNNGYRECLANGSWA 94 Query: 112 CPVPL----ELLAEEES---YFSTVKIIYTVGHSISIVALFVAITILVALR--------- 155 V E+L EE+ ++ II +GH IS+VAL VA + + LR Sbjct: 95 ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQ 154 Query: 156 --------------------RLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDTDHC 195 + C RN +H L + FIL+ F+ + + Sbjct: 155 ADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEVHQSNV 214 Query: 196 SFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVL 255 + C++ AA ++ +TNF W+ E YL+ + T + R W + GWG+P Sbjct: 215 GW----CRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFP 270 Query: 256 FTGTWVSCKLAFEDIACWDLDDTSPYW-WIIKGPIVLSVGVNFGLFLNIIRILVRKLEPA 314 W KL +++ CW Y +I +GP++L + +NF NI+RIL+ KL + Sbjct: 271 IIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRAS 330 Query: 315 QGS 317 S Sbjct: 331 TTS 333 >gi|223717978 corticotropin releasing hormone receptor 1 isoform 3 [Homo sapiens] Length = 375 Score = 108 bits (271), Expect = 5e-24 Identities = 63/205 (30%), Positives = 102/205 (49%), Gaps = 8/205 (3%) Query: 117 ELLAEEES---YFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFI 173 E+L EE+ ++ II +GH IS+VAL VA + + LR + C RN +H L + FI Sbjct: 64 EILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFI 123 Query: 174 LKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLAS 233 L+ F+ + + + C++ AA ++ +TNF W+ E YL+ + Sbjct: 124 LRNATWFVVQLTMSPEVHQSNVGW----CRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVL 179 Query: 234 TSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYW-WIIKGPIVLS 292 T + R W + GWG+P W KL +++ CW Y +I +GP++L Sbjct: 180 TYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILV 239 Query: 293 VGVNFGLFLNIIRILVRKLEPAQGS 317 + +NF NI+RIL+ KL + S Sbjct: 240 LLINFIFLFNIVRILMTKLRASTTS 264 >gi|5031621 calcitonin receptor-like [Homo sapiens] Length = 461 Score = 105 bits (263), Expect = 4e-23 Identities = 70/261 (26%), Positives = 115/261 (44%), Gaps = 7/261 (2%) Query: 55 CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITG-WSEPFPPYPVACP 113 C TWDG LCW +G CPD+F F S V + C G W Sbjct: 65 CNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDP-SEKVTKICDQDGNWFRHPASNRTWTN 123 Query: 114 VPLELLAEEESYFSTVKIIYT--VGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTT 171 + E + + + Y +GH +SI +L +++ I + L C R +H LF + Sbjct: 124 YTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFS 183 Query: 172 FILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLL 231 F+ + + A+ ++ + + V CKVS + N+ W+L E +YL+ L+ Sbjct: 184 FVCNSVVTIIHLTAVANNQAL--VATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLI 241 Query: 232 ASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVL 291 + ++ W GWG P++ + + + CW DT +II GPI Sbjct: 242 VVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTH-LLYIIHGPICA 300 Query: 292 SVGVNFGLFLNIIRILVRKLE 312 ++ VN LNI+R+L+ KL+ Sbjct: 301 ALLVNLFFLLNIVRVLITKLK 321 >gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo sapiens] Length = 652 Score = 57.4 bits (137), Expect = 2e-08 Identities = 56/214 (26%), Positives = 88/214 (41%), Gaps = 20/214 (9%) Query: 114 VPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFI 173 V + L ++EE TV I VG S+S++ L +A + + + +H QL Sbjct: 343 VLMALTSQEEDPVLTV--ITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLF 400 Query: 174 LKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL-----N 228 L A +FL D T+ VLC + A H+ + F+W+L E V+L N Sbjct: 401 L-AHLLFLVGI-----DRTE----PKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARN 450 Query: 229 CLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIA--CWDLDDTSPYWWIIK 286 + + S +R W + G+G+P + + A CW L + W Sbjct: 451 LTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCW-LHLDQGFMWSFL 509 Query: 287 GPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHT 320 GP+ N LF+ + IL RKL + T Sbjct: 510 GPVCAIFSANLVLFILVFWILKRKLSSLNSEVST 543 >gi|163792198 latrophilin 3 precursor [Homo sapiens] Length = 1469 Score = 56.6 bits (135), Expect = 3e-08 Identities = 55/179 (30%), Positives = 79/179 (44%), Gaps = 22/179 (12%) Query: 131 IIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSD 190 +I VG +S+V L + I R L RN +H L + + A +FL + Sbjct: 879 VITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFV-AELLFL-----IGIN 932 Query: 191 DTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLAST--SPSSRRAFWWLVLA 248 TD + C V A HF + F+W+ E V L +L S SRR +++LV Sbjct: 933 RTDQ----PIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLV-- 986 Query: 249 GWGLPVLFTGTWVSCKLAFE----DIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNI 303 G+G+P L VS + + D CW DT W I GP L + +N +FL I Sbjct: 987 GYGMPALIVA--VSAAVDYRSYGTDKVCWLRLDTYFIWSFI-GPATLIIMLNV-IFLGI 1041 >gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens] Length = 1474 Score = 55.8 bits (133), Expect = 5e-08 Identities = 52/199 (26%), Positives = 79/199 (39%), Gaps = 18/199 (9%) Query: 118 LLAEEESYFSTVK-----IIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTF 172 L+A E Y + +I VG IS+V L + I+ LR L RN +H L Sbjct: 844 LMAHREIYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINL 903 Query: 173 ILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLA 232 L A +FL D T + + C + H+ + FSWL E V+L LL Sbjct: 904 FL-AELLFLVGI-----DKTQY----EIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLV 953 Query: 233 STSPSSRRAFWWLVLAGWGLPVLFTG--TWVSCKLAFEDIACWDLDDTSPYWWIIKGPIV 290 S + L G+ P L G + + + ACW L + + W GP+ Sbjct: 954 EVFESEYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACW-LRVDNYFIWSFIGPVS 1012 Query: 291 LSVGVNFGLFLNIIRILVR 309 + VN + + ++R Sbjct: 1013 FVIVVNLVFLMVTLHKMIR 1031 >gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens] Length = 1469 Score = 55.8 bits (133), Expect = 5e-08 Identities = 52/199 (26%), Positives = 79/199 (39%), Gaps = 18/199 (9%) Query: 118 LLAEEESYFSTVK-----IIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTF 172 L+A E Y + +I VG IS+V L + I+ LR L RN +H L Sbjct: 839 LMAHREIYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINL 898 Query: 173 ILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLA 232 L A +FL D T + + C + H+ + FSWL E V+L LL Sbjct: 899 FL-AELLFLVGI-----DKTQY----EIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLV 948 Query: 233 STSPSSRRAFWWLVLAGWGLPVLFTG--TWVSCKLAFEDIACWDLDDTSPYWWIIKGPIV 290 S + L G+ P L G + + + ACW L + + W GP+ Sbjct: 949 EVFESEYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACW-LRVDNYFIWSFIGPVS 1007 Query: 291 LSVGVNFGLFLNIIRILVR 309 + VN + + ++R Sbjct: 1008 FVIVVNLVFLMVTLHKMIR 1026 >gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo sapiens] Length = 3014 Score = 53.9 bits (128), Expect = 2e-07 Identities = 46/186 (24%), Positives = 73/186 (39%), Gaps = 15/186 (8%) Query: 114 VPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFI 173 V +++ E +KI+ S+S+ AL VA +L +R L + +H L Sbjct: 2453 VLMDISRRENGEVLPLKIVTYAAVSLSLAALLVAFVLLSLVRMLRSNLHSIHKHL----- 2507 Query: 174 LKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLAS 233 A A+FL + F LC V H+ M+ F+W L E++++ +L Sbjct: 2508 --AVALFLSQLVFVIGINQTENPF---LCTVVAILLHYIYMSTFAWTLVESLHVYRMLTE 2562 Query: 234 TSPSSRRAFWWLVLAGWGLPVLFTGTWVSCK---LAFEDIACWDLDDTSPYWWIIKGPIV 290 + + GWG+P + TG V D L DT W GPI Sbjct: 2563 VRNIDTGPMRFYYVVGWGIPAIVTGLAVGLDPQGYGNPDFCWLSLQDT--LIWSFAGPIG 2620 Query: 291 LSVGVN 296 + +N Sbjct: 2621 AVIIIN 2626 Score = 30.4 bits (67), Expect = 2.3 Identities = 15/51 (29%), Positives = 21/51 (41%), Gaps = 5/51 (9%) Query: 54 GCPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEP 104 GCP ++ + WP G+ +PCP S AV+ GW P Sbjct: 2054 GCPKAFEAGIWWPQTKFGQPAAVPCPK-----GSVGNAVRHCSGEKGWLPP 2099 >gi|45433552 G protein-coupled receptor 133 [Homo sapiens] Length = 874 Score = 53.9 bits (128), Expect = 2e-07 Identities = 44/198 (22%), Positives = 80/198 (40%), Gaps = 17/198 (8%) Query: 114 VPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFI 173 VPLEL + S++ + + +VA V +L ++ + R ++H L Sbjct: 554 VPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANL----- 608 Query: 174 LKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLAS 233 + AV + L S + T C+V H+ ++ F+W+L E ++L ++ Sbjct: 609 --SFAVLVAQVLLLISFRLEP---GTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIK 663 Query: 234 TSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIA----CWDLDDTSPYWWIIKGPI 289 S + GWG P+L +S A + CW L S W P Sbjct: 664 VFGSEDSKHRYYYGMGWGFPLLI--CIISLSFAMDSYGTSNNCW-LSLASGAIWAFVAPA 720 Query: 290 VLSVGVNFGLFLNIIRIL 307 + + VN G+ + + R++ Sbjct: 721 LFVIVVNIGILIAVTRVI 738 >gi|23397681 egf-like module containing, mucin-like, hormone receptor-like sequence 2 isoform a [Homo sapiens] Length = 823 Score = 51.6 bits (122), Expect = 1e-06 Identities = 60/259 (23%), Positives = 99/259 (38%), Gaps = 33/259 (12%) Query: 69 GSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFST 128 G G W T C + ++ + R ++ ++ Y V +EE T Sbjct: 491 GCGHWATTGCSTIGTR---DTSTICRCTHLSSFAVLMAHYDV----------QEEDPVLT 537 Query: 129 VKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFH 188 V I +G S+S++ L +A + + + +H QL L A +FL Sbjct: 538 V--ITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFL-AHLLFLVAI---- 590 Query: 189 SDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL-----NCLLASTSPSSRRAFW 243 D T H VLC + H+ + +W+L EA+YL N + + S +R Sbjct: 591 -DQTGH----KVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKK 645 Query: 244 WLVLAGWGLPVLFTGTWVSCK--LAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFL 301 + G+G+P + + + L CW L + W GP+ VN LFL Sbjct: 646 LMFPVGYGVPAVTVAISAASRPHLYGTPSRCW-LQPEKGFIWGFLGPVCAIFSVNLVLFL 704 Query: 302 NIIRILVRKLEPAQGSLHT 320 + IL +L + T Sbjct: 705 VTLWILKNRLSSLNSEVST 723 >gi|23397693 egf-like module containing, mucin-like, hormone receptor-like sequence 2 isoform g [Homo sapiens] Length = 719 Score = 51.6 bits (122), Expect = 1e-06 Identities = 60/259 (23%), Positives = 99/259 (38%), Gaps = 33/259 (12%) Query: 69 GSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFST 128 G G W T C + ++ + R ++ ++ Y V +EE T Sbjct: 387 GCGHWATTGCSTIGTR---DTSTICRCTHLSSFAVLMAHYDV----------QEEDPVLT 433 Query: 129 VKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFH 188 V I +G S+S++ L +A + + + +H QL L A +FL Sbjct: 434 V--ITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFL-AHLLFLVAI---- 486 Query: 189 SDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL-----NCLLASTSPSSRRAFW 243 D T H VLC + H+ + +W+L EA+YL N + + S +R Sbjct: 487 -DQTGH----KVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKK 541 Query: 244 WLVLAGWGLPVLFTGTWVSCK--LAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFL 301 + G+G+P + + + L CW L + W GP+ VN LFL Sbjct: 542 LMFPVGYGVPAVTVAISAASRPHLYGTPSRCW-LQPEKGFIWGFLGPVCAIFSVNLVLFL 600 Query: 302 NIIRILVRKLEPAQGSLHT 320 + IL +L + T Sbjct: 601 VTLWILKNRLSSLNSEVST 619 >gi|23397691 egf-like module containing, mucin-like, hormone receptor-like sequence 2 isoform f [Homo sapiens] Length = 763 Score = 51.6 bits (122), Expect = 1e-06 Identities = 60/259 (23%), Positives = 99/259 (38%), Gaps = 33/259 (12%) Query: 69 GSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFST 128 G G W T C + ++ + R ++ ++ Y V +EE T Sbjct: 431 GCGHWATTGCSTIGTR---DTSTICRCTHLSSFAVLMAHYDV----------QEEDPVLT 477 Query: 129 VKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFH 188 V I +G S+S++ L +A + + + +H QL L A +FL Sbjct: 478 V--ITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFL-AHLLFLVAI---- 530 Query: 189 SDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL-----NCLLASTSPSSRRAFW 243 D T H VLC + H+ + +W+L EA+YL N + + S +R Sbjct: 531 -DQTGH----KVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKK 585 Query: 244 WLVLAGWGLPVLFTGTWVSCK--LAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFL 301 + G+G+P + + + L CW L + W GP+ VN LFL Sbjct: 586 LMFPVGYGVPAVTVAISAASRPHLYGTPSRCW-LQPEKGFIWGFLGPVCAIFSVNLVLFL 644 Query: 302 NIIRILVRKLEPAQGSLHT 320 + IL +L + T Sbjct: 645 VTLWILKNRLSSLNSEVST 663 >gi|23397689 egf-like module containing, mucin-like, hormone receptor-like sequence 2 isoform e [Homo sapiens] Length = 812 Score = 51.6 bits (122), Expect = 1e-06 Identities = 60/259 (23%), Positives = 99/259 (38%), Gaps = 33/259 (12%) Query: 69 GSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFST 128 G G W T C + ++ + R ++ ++ Y V +EE T Sbjct: 480 GCGHWATTGCSTIGTR---DTSTICRCTHLSSFAVLMAHYDV----------QEEDPVLT 526 Query: 129 VKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFH 188 V I +G S+S++ L +A + + + +H QL L A +FL Sbjct: 527 V--ITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFL-AHLLFLVAI---- 579 Query: 189 SDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL-----NCLLASTSPSSRRAFW 243 D T H VLC + H+ + +W+L EA+YL N + + S +R Sbjct: 580 -DQTGH----KVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKK 634 Query: 244 WLVLAGWGLPVLFTGTWVSCK--LAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFL 301 + G+G+P + + + L CW L + W GP+ VN LFL Sbjct: 635 LMFPVGYGVPAVTVAISAASRPHLYGTPSRCW-LQPEKGFIWGFLGPVCAIFSVNLVLFL 693 Query: 302 NIIRILVRKLEPAQGSLHT 320 + IL +L + T Sbjct: 694 VTLWILKNRLSSLNSEVST 712 >gi|23397687 egf-like module containing, mucin-like, hormone receptor-like sequence 2 isoform d [Homo sapiens] Length = 681 Score = 51.6 bits (122), Expect = 1e-06 Identities = 60/259 (23%), Positives = 99/259 (38%), Gaps = 33/259 (12%) Query: 69 GSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFST 128 G G W T C + ++ + R ++ ++ Y V +EE T Sbjct: 349 GCGHWATTGCSTIGTR---DTSTICRCTHLSSFAVLMAHYDV----------QEEDPVLT 395 Query: 129 VKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFH 188 V I +G S+S++ L +A + + + +H QL L A +FL Sbjct: 396 V--ITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFL-AHLLFLVAI---- 448 Query: 189 SDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL-----NCLLASTSPSSRRAFW 243 D T H VLC + H+ + +W+L EA+YL N + + S +R Sbjct: 449 -DQTGH----KVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKK 503 Query: 244 WLVLAGWGLPVLFTGTWVSCK--LAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFL 301 + G+G+P + + + L CW L + W GP+ VN LFL Sbjct: 504 LMFPVGYGVPAVTVAISAASRPHLYGTPSRCW-LQPEKGFIWGFLGPVCAIFSVNLVLFL 562 Query: 302 NIIRILVRKLEPAQGSLHT 320 + IL +L + T Sbjct: 563 VTLWILKNRLSSLNSEVST 581 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.325 0.138 0.472 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,128,964 Number of Sequences: 37866 Number of extensions: 667587 Number of successful extensions: 2081 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 41 Number of HSP's successfully gapped in prelim test: 44 Number of HSP's that attempted gapping in prelim test: 1943 Number of HSP's gapped (non-prelim): 102 length of query: 337 length of database: 18,247,518 effective HSP length: 103 effective length of query: 234 effective length of database: 14,347,320 effective search space: 3357272880 effective search space used: 3357272880 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.