Search of human proteins with 58530851

Search of human proteins with 58530851

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|58530851 growth hormone releasing hormone receptor isoform a
precursor [Homo sapiens]
         (423 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|58530851 growth hormone releasing hormone receptor isoform a ...   889   0.0  
gi|58530853 growth hormone releasing hormone receptor isoform b ...   688   0.0  
gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]   353   1e-97
gi|29171759 adenylate cyclase activating polypeptide 1 (pituitar...   340   1e-93
gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]   338   5e-93
gi|114205383 secretin receptor precursor [Homo sapiens]               338   5e-93
gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]    249   3e-66
gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapi...   233   2e-61
gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]    233   3e-61
gi|4503947 glucagon receptor [Homo sapiens]                           231   9e-61
gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]     225   5e-59
gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]          223   3e-58
gi|19923245 corticotropin releasing hormone receptor 1 isoform 2...   177   1e-44
gi|32307159 corticotropin releasing hormone receptor 2 [Homo sap...   171   2e-42
gi|223717971 corticotropin releasing hormone receptor 1 isoform ...   162   5e-40
gi|223717978 corticotropin releasing hormone receptor 1 isoform ...   161   9e-40
gi|4502547 calcitonin receptor [Homo sapiens]                         160   3e-39
gi|223717985 corticotropin releasing hormone receptor 1 isoform ...   146   4e-35
gi|5031621 calcitonin receptor-like [Homo sapiens]                    137   1e-32
gi|45433552 G protein-coupled receptor 133 [Homo sapiens]              76   5e-14
gi|240120161 G protein-coupled receptor 144 [Homo sapiens]             72   9e-13
gi|133930786 egf-like module-containing mucin-like receptor 3 [H...    72   1e-12
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]            69   6e-12
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]            69   6e-12
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]            69   6e-12
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]           69   1e-11
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]           69   1e-11
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s...    65   2e-10
gi|163792198 latrophilin 3 precursor [Homo sapiens]                    65   2e-10
gi|23397681 egf-like module containing, mucin-like, hormone rece...    64   2e-10

>gi|58530851 growth hormone releasing hormone receptor isoform a
           precursor [Homo sapiens]
          Length = 423

 Score =  889 bits (2297), Expect = 0.0
 Identities = 423/423 (100%), Positives = 423/423 (100%)

Query: 1   MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD 60
           MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD
Sbjct: 1   MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD 60

Query: 61  GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA 120
           GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA
Sbjct: 61  GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA 120

Query: 121 EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF 180
           EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF
Sbjct: 121 EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF 180

Query: 181 LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR 240
           LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR
Sbjct: 181 LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR 240

Query: 241 AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF 300
           AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF
Sbjct: 241 AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF 300

Query: 301 LNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPL 360
           LNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPL
Sbjct: 301 LNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPL 360

Query: 361 ELGLGSFQGFIVAILYCFLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKVLT 420
           ELGLGSFQGFIVAILYCFLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKVLT
Sbjct: 361 ELGLGSFQGFIVAILYCFLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKVLT 420

Query: 421 SMC 423
           SMC
Sbjct: 421 SMC 423


>gi|58530853 growth hormone releasing hormone receptor isoform b
           precursor [Homo sapiens]
          Length = 337

 Score =  688 bits (1776), Expect = 0.0
 Identities = 325/325 (100%), Positives = 325/325 (100%)

Query: 1   MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD 60
           MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD
Sbjct: 1   MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD 60

Query: 61  GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA 120
           GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA
Sbjct: 61  GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA 120

Query: 121 EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF 180
           EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF
Sbjct: 121 EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF 180

Query: 181 LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR 240
           LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR
Sbjct: 181 LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR 240

Query: 241 AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF 300
           AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF
Sbjct: 241 AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF 300

Query: 301 LNIIRILVRKLEPAQGSLHTQSQYW 325
           LNIIRILVRKLEPAQGSLHTQSQYW
Sbjct: 301 LNIIRILVRKLEPAQGSLHTQSQYW 325


>gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]
          Length = 457

 Score =  353 bits (907), Expect = 1e-97
 Identities = 181/414 (43%), Positives = 246/414 (59%), Gaps = 7/414 (1%)

Query: 14  LSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEW 73
           L P       +  ECD++  +      CL+ A+ + N T+GC   WD L CWP    G+ 
Sbjct: 23  LGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQ-LENETIGCSKMWDNLTCWPATPRGQV 81

Query: 74  VTLPCPDFFSHFSSESGA-VKRDCTITGWSEPFP-PYPVACPVPLELLAEEES---YFST 128
           V L CP  F  FSS  G  V R CT  GW+   P PYP+AC +  +  + +E    ++ +
Sbjct: 82  VVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASLDEQQTMFYGS 141

Query: 129 VKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFH 188
           VK  YT+G+ +S+  L VA  IL   R+LHC RNY+H  LF +FIL+A AVF+KD ALF 
Sbjct: 142 VKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFD 201

Query: 189 SDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLA 248
           S ++D CS  +V CK ++    +  M NF WLL E +YL  LLA +  S R+ FW  +L 
Sbjct: 202 SGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILI 261

Query: 249 GWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILV 308
           GWG+P  FT  W   ++ FED  CWD  ++S  WWIIKGPI+ S+ VNF LF+ IIRIL+
Sbjct: 262 GWGVPSTFTMVWTIARIHFEDYGCWDTINSS-LWWIIKGPILTSILVNFILFICIIRILL 320

Query: 309 RKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGSFQ 368
           +KL P        S Y RL++STL LIPLFG+HYI+F F PDN    +++  EL +GSFQ
Sbjct: 321 QKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGSFQ 380

Query: 369 GFIVAILYCFLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKVLTSM 422
           GF+VAILYCFLN EV+ E+ RKW     + +  W  + +  +   + A   T +
Sbjct: 381 GFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCSTQV 434


>gi|29171759 adenylate cyclase activating polypeptide 1 (pituitary)
           receptor type I precursor [Homo sapiens]
          Length = 468

 Score =  340 bits (872), Expect = 1e-93
 Identities = 172/399 (43%), Positives = 238/399 (59%), Gaps = 35/399 (8%)

Query: 24  MHPECDFITQLREDESACL---QAAEEMP---NTTLGCPATWDGLLCWPTAGSGEWVTLP 77
           MH +C F    +++++ CL   Q A E+    +++ GCP  WD + CW  A  GE V + 
Sbjct: 21  MHSDCIF----KKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVLVS 76

Query: 78  CPDFFSHFS-----------------------SESGAVKRDCTITGWSEPFPPYPVACPV 114
           CP+ F  F+                       S+ G V R+CT  GWSEPFP Y  AC  
Sbjct: 77  CPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGF 136

Query: 115 PL--ELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTF 172
                   +++ Y+ +VK +YTVG+S S+V L  A+ IL   R+LHC RN++H  LF +F
Sbjct: 137 DEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSF 196

Query: 173 ILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLA 232
           +L+A +VF+KD  L+   D++HC  STV CK  +   H+  ++N+ WL  E +YL  LL 
Sbjct: 197 MLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLV 256

Query: 233 STSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLS 292
            T    RR F+W  + GWG P +    W + +L F+D  CWD++D++  WW+IKGP+V S
Sbjct: 257 ETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGS 316

Query: 293 VGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNA 352
           + VNF LF+ II ILV+KL+      +  S Y RL++STL LIPLFGIHY +F F P+N 
Sbjct: 317 IMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSPENV 376

Query: 353 GLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKW 391
               RL  ELGLGSFQGF+VA+LYCFLN EV+ EI RKW
Sbjct: 377 SKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKW 415


>gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]
          Length = 438

 Score =  338 bits (867), Expect = 5e-93
 Identities = 166/376 (44%), Positives = 231/376 (61%), Gaps = 4/376 (1%)

Query: 24  MHPECDFITQLREDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFS 83
           +HPEC F  +++E+E+ C +           C   WD + CW  A  GE VT+PCP  FS
Sbjct: 21  IHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNITCWRPANVGETVTVPCPKVFS 80

Query: 84  HFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVA 143
           +F S++G + ++CT  GWSE FP +  AC         + +++  VK IYT+G+S+S+++
Sbjct: 81  NFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMS 140

Query: 144 LFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDTDHCS---FSTV 200
           L     IL   R+LHC RNY+H  LF +FIL+A +V +KD  L+ S  T HC     S V
Sbjct: 141 LATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWV 200

Query: 201 LCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTW 260
            CK+S+    +  M NF WLL E +YL+ LL +  P  RR F   +L GWGLP +  G W
Sbjct: 201 GCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPP-RRCFLAYLLIGWGLPTVCIGAW 259

Query: 261 VSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHT 320
            + +L  ED  CWD +D S  WW+I+ PI++S+ VNF LF++IIRIL++KL       + 
Sbjct: 260 TAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGND 319

Query: 321 QSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGSFQGFIVAILYCFLN 380
           QSQY RL+KSTL LIPLFG+HY++F   P +     ++  EL LGSFQG +VA+LYCFLN
Sbjct: 320 QSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFELCLGSFQGLVVAVLYCFLN 379

Query: 381 QEVRTEISRKWHGHDP 396
            EV+ E+ RKW    P
Sbjct: 380 SEVQCELKRKWRSRCP 395


>gi|114205383 secretin receptor precursor [Homo sapiens]
          Length = 440

 Score =  338 bits (867), Expect = 5e-93
 Identities = 168/373 (45%), Positives = 232/373 (62%), Gaps = 10/373 (2%)

Query: 28  CDFITQLREDESACLQAAEEMPNTTLG-------CPATWDGLLCWPTAGSGEWVTLPCPD 80
           CD +  L E++  CLQ         LG       C   WD + CWP++  G  V + CP 
Sbjct: 32  CDVLQVLWEEQDQCLQELSREQTGDLGTEQPVPGCEGMWDNISCWPSSVPGRMVEVECPR 91

Query: 81  FFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEE--SYFSTVKIIYTVGHS 138
           F    +S +G++ R+CT  GWSE FP   +AC V +   + E+  SY   +K++YTVG+S
Sbjct: 92  FLRMLTSRNGSLFRNCTQDGWSETFPRPNLACGVNVNDSSNEKRHSYLLKLKVMYTVGYS 151

Query: 139 ISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDTDHCSFS 198
            S+V L VA+ IL A RRLHC RNY+H  LF +FIL+A + F+KDA LF SDD  +C   
Sbjct: 152 SSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAH 211

Query: 199 TVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTG 258
              CK+ +    +  M N+SWLL E +YL+ LLA +  S R+     V  GWG P +F  
Sbjct: 212 RAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVA 271

Query: 259 TWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSL 318
            W   +   ED+ CWD++  +  WWII+GP++LS+ +NF LF+NI+RIL+RKL   +   
Sbjct: 272 LWAIARHFLEDVGCWDINANASIWWIIRGPVILSILINFILFINILRILMRKLRTQETRG 331

Query: 319 HTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGSFQGFIVAILYCF 378
           +  S Y RL++STL LIPLFGIHYI+F F P++A + I+L  EL LGSFQG +VA+LYCF
Sbjct: 332 NEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDA-MEIQLFFELALGSFQGLVVAVLYCF 390

Query: 379 LNQEVRTEISRKW 391
           LN EV+ E+ +KW
Sbjct: 391 LNGEVQLEVQKKW 403


>gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]
          Length = 593

 Score =  249 bits (636), Expect = 3e-66
 Identities = 139/369 (37%), Positives = 195/369 (52%), Gaps = 34/369 (9%)

Query: 55  CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA--- 111
           C   WD +LCWP    GE V +PCPD+   F+ +  A +R C   G  E  P +      
Sbjct: 108 CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRR-CDRNGSWELVPGHNRTWAN 166

Query: 112 ---CPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQL 168
              C   L     E   F  + +IYTVG+S+S+ +L VA+ IL   RRLHC RNY+H  L
Sbjct: 167 YSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHL 226

Query: 169 FTTFILKAGAVFLKDAALFHSDDTDHCSFST---------------------VLCKVSVA 207
           F +F+L+A ++F+KDA L+     D     T                       C+V+V 
Sbjct: 227 FLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVT 286

Query: 208 ASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAF 267
              +   TN+ W+L E +YL+ L+     S ++  W   + GWGLP +F   WVS +   
Sbjct: 287 FFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATL 346

Query: 268 EDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKL-EPAQGSLHTQSQYWR 326
            +  CWDL   +   WII+ PI+ S+ +NF LF+NI+R+L  KL E   G   T+ QY +
Sbjct: 347 ANTGCWDLSSGNKK-WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRK 405

Query: 327 LSKSTLFLIPLFGIHYIIFNFLPDNAGLG----IRLPLELGLGSFQGFIVAILYCFLNQE 382
           L KSTL L+PLFG+HYI+F   P     G    +++  E+   SFQGF VAI+YCF N E
Sbjct: 406 LLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGE 465

Query: 383 VRTEISRKW 391
           V+ EI + W
Sbjct: 466 VQAEIKKSW 474


>gi|4758438 glucagon-like peptide 2 receptor precursor [Homo
           sapiens]
          Length = 553

 Score =  233 bits (594), Expect = 2e-61
 Identities = 136/376 (36%), Positives = 205/376 (54%), Gaps = 26/376 (6%)

Query: 38  ESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSES-GAVKRDC 96
           + ACL+   + P+    C  T+D  +CWP +  G  V++PCP +   +S ES G   R C
Sbjct: 80  KQACLRDLLKEPSGIF-CNGTFDQYVCWPHSSPGN-VSVPCPSYLPWWSEESSGRAYRHC 137

Query: 97  TITG-WSEPFPPYPV-----ACPVPLELLAEEESY--FSTVKIIYTVGHSISIVALFVAI 148
              G W        +      C          + Y   ST++++YTVG+S S+++LF+A+
Sbjct: 138 LAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLAL 197

Query: 149 TILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDT---------DHCSFST 199
           T+L+ LR+LHC RNY+H  LF +FIL+  AV +KD   ++S             + S  +
Sbjct: 198 TLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMS 257

Query: 200 VLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGT 259
             C+      H+    N+ WLL E +YL+ LL  T    RR +   +L GW  PVLF   
Sbjct: 258 TSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVP 317

Query: 260 WVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLH 319
           W   +   E+  CW  +     WWII+GP++L V VNF +FL I+++L+ KL+  Q  + 
Sbjct: 318 WGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQ--MC 375

Query: 320 TQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLG----IRLPLELGLGSFQGFIVAIL 375
            +   +RL+KSTL LIPL G+H I+F+F+ D+   G    IRL ++L L SF GF+VA+ 
Sbjct: 376 FRDYKYRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQ 435

Query: 376 YCFLNQEVRTEISRKW 391
           Y F N EV+ E+ + W
Sbjct: 436 YGFANGEVKAELRKYW 451


>gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]
          Length = 550

 Score =  233 bits (593), Expect = 3e-61
 Identities = 139/406 (34%), Positives = 205/406 (50%), Gaps = 51/406 (12%)

Query: 55  CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITG-----------WSE 103
           C   WDGL+CWP    G+   +PCP +   F+ + G   R C   G           W+ 
Sbjct: 63  CFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHK-GVAFRHCNPNGTWDFMHSLNKTWAN 121

Query: 104 PFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNY 163
                    P   ++   ++ +F  + ++YTVG+SIS  +L VAI I+   RRLHC RNY
Sbjct: 122 YSDCLRFLQP---DISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNY 178

Query: 164 VHTQLFTTFILKAGAVFLKD------------AALFHSDDTDHCSFST-------VLCKV 204
           +H  LF +F+L+A ++F+KD             +L   DD  +   +T       + CK+
Sbjct: 179 IHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKI 238

Query: 205 SVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCK 264
           +V    +   TN+ W+L E +YL+ L+     S  +  W  +L GWG P  F   W   +
Sbjct: 239 AVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVAR 298

Query: 265 LAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLH-TQSQ 323
               D  CW+L       WI + PI+ ++G+NF LFLN +R+L  K+       H T+ Q
Sbjct: 299 ATLADARCWEL-SAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQ 357

Query: 324 YWRLSKSTLFLIPLFGIHYIIFNFLPDN-AGLG--IRLPLELGLGSFQGFIVAILYCFLN 380
           Y +L+KSTL L+ +FG+HYI+F  LP +  GLG  IR+  EL   SFQGF V+I+YC+ N
Sbjct: 358 YRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCN 417

Query: 381 QEVRTEISRKWHGHDPELLPAWRTRAKW-TTP---SRSAAKVLTSM 422
            EV+ E+ + W          W     W  TP   SR    VLT++
Sbjct: 418 GEVQAEVKKMW--------SRWNLSVDWKRTPPCGSRRCGSVLTTV 455


>gi|4503947 glucagon receptor [Homo sapiens]
          Length = 477

 Score =  231 bits (589), Expect = 9e-61
 Identities = 132/367 (35%), Positives = 200/367 (54%), Gaps = 25/367 (6%)

Query: 49  PNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFS-HFSSESGAVKRDCTITGWSEPFP- 106
           P T L C  T+D   CWP   +     + CP +   H   +   V + C   G     P 
Sbjct: 52  PPTELVCNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPR 111

Query: 107 --PYPVA--CPVP---LELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHC 159
             P+  A  C +    +E+  E    +S+ +++YTVG+S+S+ AL +A+ IL  L +LHC
Sbjct: 112 GQPWRDASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHC 171

Query: 160 PRNYVHTQLFTTFILKAGAVFLKDAAL---FHSDDTDHCSFSTVL-------CKVSVAAS 209
            RN +H  LF +F+LKA +V + D  L   +     D  S ST L       C+V+    
Sbjct: 172 TRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFM 231

Query: 210 HFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFED 269
            +  + N+ WLL E +YL+ LL   +   R  F   +  GWG P+LF   W   K  FE+
Sbjct: 232 QYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFEN 291

Query: 270 IACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSK 329
           + CW  +D   +WWI++ P+ L++ +NF +F+ I+++LV KL   Q  +H     +RL+K
Sbjct: 292 VQCWTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQ--MHHTDYKFRLAK 349

Query: 330 STLFLIPLFGIHYIIFNFLPDNAGLG----IRLPLELGLGSFQGFIVAILYCFLNQEVRT 385
           STL LIPL G+H ++F F+ D    G     +L  +L L SFQG +VA+LYCFLN+EV++
Sbjct: 350 STLTLIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQS 409

Query: 386 EISRKWH 392
           E+ R+WH
Sbjct: 410 ELRRRWH 416


>gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]
          Length = 466

 Score =  225 bits (574), Expect = 5e-59
 Identities = 126/370 (34%), Positives = 197/370 (53%), Gaps = 16/370 (4%)

Query: 35  REDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFS-HFSSESGAVK 93
           R +    L AAE  P + L C  ++D  +CW  A         CP +   H    +G V 
Sbjct: 43  RRECQETLAAAE--PPSGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVL 100

Query: 94  RDCTITG-WSEPFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILV 152
           R C   G W           P   E   ++      ++++YTVG+S+S+  L +A+ IL 
Sbjct: 101 RQCGSDGQWGLWRDHTQCENPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILS 160

Query: 153 ALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALF----HSDDTDHCSFSTVL--CKVSV 206
             RRLHC RNY+H  LFT+F+L+A A+  +D  L     +  D     ++  L  C+ + 
Sbjct: 161 LFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQ 220

Query: 207 AASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLA 266
             + +    N++WLL E VYL+ LL     S    F + +L GWG P LF   WV  +  
Sbjct: 221 IVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYL 280

Query: 267 FEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWR 326
           +E+  CW+ ++    WWII+ PI++++ +NF +F+ I+ IL+ KL   Q  +  +    R
Sbjct: 281 YENTQCWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQ--MRCRDYRLR 338

Query: 327 LSKSTLFLIPLFGIHYIIFNFLPDNAGLG----IRLPLELGLGSFQGFIVAILYCFLNQE 382
           L++STL L+PL G+H ++F  + +    G     +L  E+ L SFQGF+V++LYCF+N+E
Sbjct: 339 LARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKE 398

Query: 383 VRTEISRKWH 392
           V++EI R WH
Sbjct: 399 VQSEIRRGWH 408


>gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]
          Length = 463

 Score =  223 bits (568), Expect = 3e-58
 Identities = 146/384 (38%), Positives = 198/384 (51%), Gaps = 25/384 (6%)

Query: 31  ITQLREDESACLQAAEE--MPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSS- 87
           + + RE    C ++  E   P T L C  T+D   CWP    G +V + CP +    SS 
Sbjct: 36  VQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSV 95

Query: 88  ESGAVKRDCTITG-W------SEPFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSIS 140
             G V R CT  G W      S P+              +  E     + IIYTVG+++S
Sbjct: 96  PQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALS 155

Query: 141 IVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAAL--FHSDDTDHCSFS 198
             AL +A  IL+  R LHC RNY+H  LF +FIL+A +VF+KDAAL   +S       + 
Sbjct: 156 FSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWD 215

Query: 199 TVL-------CKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWG 251
            +L       C++      +    N+ WLL E VYL  LLA +  S +  F   V  GWG
Sbjct: 216 GLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWG 275

Query: 252 LPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKL 311
           +P+LF   W   K  +ED  CW  +    YW II+ PI+ ++GVNF +F+ +I I+V KL
Sbjct: 276 VPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKL 335

Query: 312 EPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLG----IRLPLELGLGSF 367
           + A     T  +  RL+KSTL LIPL G H +IF F+ D    G    I+L  EL   SF
Sbjct: 336 K-ANLMCKTDIK-CRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSF 393

Query: 368 QGFIVAILYCFLNQEVRTEISRKW 391
           QG +VAILYCF+N EV+ E  + W
Sbjct: 394 QGLMVAILYCFVNNEVQLEFRKSW 417


>gi|19923245 corticotropin releasing hormone receptor 1 isoform 2
           [Homo sapiens]
          Length = 415

 Score =  177 bits (450), Expect = 1e-44
 Identities = 115/351 (32%), Positives = 174/351 (49%), Gaps = 24/351 (6%)

Query: 53  LGCPATWDGL-LCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA 111
           L C A+ D +  CWP + +G+ V  PCP FF         V+ + T  G+ E       A
Sbjct: 42  LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFY-------GVRYNTTNNGYRECLANGSWA 94

Query: 112 CPVPL----ELLAEEES---YFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYV 164
             V      E+L EE+    ++    II  +GH IS+VAL VA  + + LR + C RN +
Sbjct: 95  ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNII 154

Query: 165 HTQLFTTFILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEA 224
           H  L + FIL+    F+    +       +  +    C++  AA ++  +TNF W+  E 
Sbjct: 155 HWNLISAFILRNATWFVVQLTMSPEVHQSNVGW----CRLVTAAYNYFHVTNFFWMFGEG 210

Query: 225 VYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYW-W 283
            YL+  +  T  + R   W  +  GWG+P      W   KL +++  CW       Y  +
Sbjct: 211 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDY 270

Query: 284 IIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYI 343
           I +GP++L + +NF    NI+RIL+ KL  +  S     QY +  K+TL L+PL GI Y+
Sbjct: 271 IYQGPMILVLLINFIFLFNIVRILMTKLRASTTS--ETIQYRKAVKATLVLLPLLGITYM 328

Query: 344 IFNFLP--DNAGLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKWH 392
           +F   P  D     + +     L SFQGF V++ YCFLN EVR+ I ++WH
Sbjct: 329 LFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWH 379


>gi|32307159 corticotropin releasing hormone receptor 2 [Homo
           sapiens]
          Length = 411

 Score =  171 bits (432), Expect = 2e-42
 Identities = 113/372 (30%), Positives = 178/372 (47%), Gaps = 25/372 (6%)

Query: 55  CPATWDGL-LCWPTAGSGEWVTLPCPDFFSHFS-SESGAVKRDCTITGWSEPFPPYPVAC 112
           C  T D +  CWP + +G  V  PCP++F+    + +    R+C   G       Y    
Sbjct: 40  CNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCE 99

Query: 113 PVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTF 172
           P+  +   + + ++    ++  +GH +S+ AL  A  + +ALR + C RN +H  L TTF
Sbjct: 100 PILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTF 159

Query: 173 ILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLA 232
           IL+    FL         D +    + V C+      ++  +TNF W+  E  YL+  + 
Sbjct: 160 ILRNVMWFLLQLV-----DHEVHESNEVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIV 214

Query: 233 STSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACW------DLDDTSPYWWIIK 286
            T  + R      +  GW +P      W   KL +E+  CW      DL D     +I +
Sbjct: 215 MTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFGKEPGDLVD-----YIYQ 269

Query: 287 GPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFN 346
           GPI+L + +NF    NI+RIL+ KL  +  S     QY +  K+TL L+PL GI Y++F 
Sbjct: 270 GPIILVLLINFVFLFNIVRILMTKLRASTTS--ETIQYRKAVKATLVLLPLLGITYMLFF 327

Query: 347 FLP--DNAGLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKWH---GHDPELLPA 401
             P  D+    + +     L SFQGF V++ YCF N EVR+ + ++WH    H    +P 
Sbjct: 328 VNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRWHRWQDHHSLRVPM 387

Query: 402 WRTRAKWTTPSR 413
            R  +  T+P+R
Sbjct: 388 ARAMSIPTSPTR 399


>gi|223717971 corticotropin releasing hormone receptor 1 isoform 1
           [Homo sapiens]
          Length = 444

 Score =  162 bits (410), Expect = 5e-40
 Identities = 115/380 (30%), Positives = 174/380 (45%), Gaps = 53/380 (13%)

Query: 53  LGCPATWDGL-LCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA 111
           L C A+ D +  CWP + +G+ V  PCP FF         V+ + T  G+ E       A
Sbjct: 42  LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFY-------GVRYNTTNNGYRECLANGSWA 94

Query: 112 CPVPL----ELLAEEES---YFSTVKIIYTVGHSISIVALFVAITILVALR--------- 155
             V      E+L EE+    ++    II  +GH IS+VAL VA  + + LR         
Sbjct: 95  ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQ 154

Query: 156 --------------------RLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDTDHC 195
                                + C RN +H  L + FIL+    F+    +       + 
Sbjct: 155 ADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEVHQSNV 214

Query: 196 SFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVL 255
            +    C++  AA ++  +TNF W+  E  YL+  +  T  + R   W  +  GWG+P  
Sbjct: 215 GW----CRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFP 270

Query: 256 FTGTWVSCKLAFEDIACWDLDDTSPYW-WIIKGPIVLSVGVNFGLFLNIIRILVRKLEPA 314
               W   KL +++  CW       Y  +I +GP++L + +NF    NI+RIL+ KL  +
Sbjct: 271 IIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRAS 330

Query: 315 QGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLP--DNAGLGIRLPLELGLGSFQGFIV 372
             S     QY +  K+TL L+PL GI Y++F   P  D     + +     L SFQGF V
Sbjct: 331 TTS--ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFV 388

Query: 373 AILYCFLNQEVRTEISRKWH 392
           ++ YCFLN EVR+ I ++WH
Sbjct: 389 SVFYCFLNSEVRSAIRKRWH 408


>gi|223717978 corticotropin releasing hormone receptor 1 isoform 3
           [Homo sapiens]
          Length = 375

 Score =  161 bits (408), Expect = 9e-40
 Identities = 95/282 (33%), Positives = 146/282 (51%), Gaps = 12/282 (4%)

Query: 117 ELLAEEES---YFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFI 173
           E+L EE+    ++    II  +GH IS+VAL VA  + + LR + C RN +H  L + FI
Sbjct: 64  EILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFI 123

Query: 174 LKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLAS 233
           L+    F+    +       +  +    C++  AA ++  +TNF W+  E  YL+  +  
Sbjct: 124 LRNATWFVVQLTMSPEVHQSNVGW----CRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVL 179

Query: 234 TSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYW-WIIKGPIVLS 292
           T  + R   W  +  GWG+P      W   KL +++  CW       Y  +I +GP++L 
Sbjct: 180 TYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILV 239

Query: 293 VGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLP--D 350
           + +NF    NI+RIL+ KL  +  S     QY +  K+TL L+PL GI Y++F   P  D
Sbjct: 240 LLINFIFLFNIVRILMTKLRASTTS--ETIQYRKAVKATLVLLPLLGITYMLFFVNPGED 297

Query: 351 NAGLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKWH 392
                + +     L SFQGF V++ YCFLN EVR+ I ++WH
Sbjct: 298 EVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWH 339


>gi|4502547 calcitonin receptor [Homo sapiens]
          Length = 474

 Score =  160 bits (404), Expect = 3e-39
 Identities = 107/346 (30%), Positives = 168/346 (48%), Gaps = 20/346 (5%)

Query: 55  CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITG-W------SEPFPP 107
           C  TWDG LCW    +G      CPD+F  F   S  V + C   G W      +  +  
Sbjct: 72  CNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDP-SEKVTKYCDEKGVWFKHPENNRTWSN 130

Query: 108 YPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQ 167
           Y +      E L  + +Y   +  +  VGHS+SI  L +++ I V  R L C R  +H  
Sbjct: 131 YTMCNAFTPEKL--KNAY--VLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKN 186

Query: 168 LFTTFILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL 227
           +F T+IL +  + +    +  + +        V CK+      +    N+ W+L E +YL
Sbjct: 187 MFLTYILNSMIIIIHLVEVVPNGEL--VRRDPVSCKILHFFHQYMMACNYFWMLCEGIYL 244

Query: 228 NCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKG 287
           + L+     + ++   W  L GWG P++ T      +  + +  CW L   +   +II G
Sbjct: 245 HTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCW-LSVETHLLYIIHG 303

Query: 288 PIVLSVGVNFGLFLNIIRILVRKL-EPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFN 346
           P++ ++ VNF   LNI+R+LV K+ E  +   H    Y +  K+T+ L+PL GI +++F 
Sbjct: 304 PVMAALVVNFFFLLNIVRVLVTKMRETHEAESH---MYLKAVKATMILVPLLGIQFVVFP 360

Query: 347 FLPDNAGLG-IRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKW 391
           + P N  LG I   +   L  FQGF VA +YCF N EV+T + R+W
Sbjct: 361 WRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQW 406


>gi|223717985 corticotropin releasing hormone receptor 1 isoform 4
           [Homo sapiens]
          Length = 401

 Score =  146 bits (368), Expect = 4e-35
 Identities = 106/351 (30%), Positives = 163/351 (46%), Gaps = 38/351 (10%)

Query: 53  LGCPATWDGL-LCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA 111
           L C A+ D +  CWP + +G+ V  PCP FF         V+ + T  G+ E       A
Sbjct: 42  LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFY-------GVRYNTTNNGYRECLANGSWA 94

Query: 112 CPVPL----ELLAEEES---YFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYV 164
             V      E+L EE+    ++    II  +GH IS+VAL VA  + + LR + C RN +
Sbjct: 95  ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNII 154

Query: 165 HTQLFTTFILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEA 224
           H  L + FIL+    F+    +       +  +    C++  AA ++  +TNF W+  E 
Sbjct: 155 HWNLISAFILRNATWFVVQLTMSPEVHQSNVGW----CRLVTAAYNYFHVTNFFWMFGEG 210

Query: 225 VYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYW-W 283
            YL+  +  T  + R   W  +  GWG+P      W   KL +++  CW       Y  +
Sbjct: 211 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDY 270

Query: 284 IIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYI 343
           I +GP++L + +NF    NI+RIL+ KL  +  S     QY +  K+TL L+PL GI Y+
Sbjct: 271 IYQGPMILVLLINFIFLFNIVRILMTKLRASTTS--ETIQYRKAVKATLVLLPLLGITYM 328

Query: 344 IFNFLP--DNAGLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKWH 392
           +F   P  D     + +     L SFQ              VR+ I ++WH
Sbjct: 329 LFFVNPGEDEVSRVVFIYFNSFLESFQ--------------VRSAIRKRWH 365


>gi|5031621 calcitonin receptor-like [Homo sapiens]
          Length = 461

 Score =  137 bits (346), Expect = 1e-32
 Identities = 92/347 (26%), Positives = 158/347 (45%), Gaps = 20/347 (5%)

Query: 55  CPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITG-WSEPFPPYPVACP 113
           C  TWDG LCW    +G      CPD+F  F   S  V + C   G W            
Sbjct: 65  CNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDP-SEKVTKICDQDGNWFRHPASNRTWTN 123

Query: 114 VPLELLAEEESYFSTVKIIYT--VGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTT 171
                +   E   + + + Y   +GH +SI +L +++ I    + L C R  +H  LF +
Sbjct: 124 YTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFS 183

Query: 172 FILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLL 231
           F+  +    +   A+ ++      + + V CKVS     +    N+ W+L E +YL+ L+
Sbjct: 184 FVCNSVVTIIHLTAVANNQAL--VATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLI 241

Query: 232 ASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVL 291
                + ++   W    GWG P++        +  + +  CW   DT    +II GPI  
Sbjct: 242 VVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTH-LLYIIHGPICA 300

Query: 292 SVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDN 351
           ++ VN    LNI+R+L+ KL+    +    + Y +  ++TL L+PL GI +++  + P+ 
Sbjct: 301 ALLVNLFFLLNIVRVLITKLKVTHQA--ESNLYMKAVRATLILVPLLGIEFVLIPWRPEG 358

Query: 352 AGLGIRLPLELG------LGSFQGFIVAILYCFLNQEVRTEISRKWH 392
                ++  E+       L  FQG +V+ ++CF N EV+  + R W+
Sbjct: 359 -----KIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWN 400


>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
          Length = 874

 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 64/282 (22%), Positives = 116/282 (41%), Gaps = 20/282 (7%)

Query: 114 VPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFI 173
           VPLEL    +   S++  +      + +VA  V   +L ++  +   R ++H  L     
Sbjct: 554 VPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANL----- 608

Query: 174 LKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLAS 233
             + AV +    L  S   +     T  C+V     H+  ++ F+W+L E ++L  ++  
Sbjct: 609 --SFAVLVAQVLLLISFRLEP---GTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIK 663

Query: 234 TSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIA----CWDLDDTSPYWWIIKGPI 289
              S      +    GWG P+L     +S   A +       CW L   S   W    P 
Sbjct: 664 VFGSEDSKHRYYYGMGWGFPLLI--CIISLSFAMDSYGTSNNCW-LSLASGAIWAFVAPA 720

Query: 290 VLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRL-SKSTLFLIPLFGIHYIIFNFL 348
           +  + VN G+ + + R+ + ++      +H     ++L +K+   L+P+ G  + +F  L
Sbjct: 721 LFVIVVNIGILIAVTRV-ISQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSW-VFGVL 778

Query: 349 PDNAGLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRK 390
             N    +   +   L S QG  + + +C LN EVR     K
Sbjct: 779 AVNGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAFKHK 820


>gi|240120161 G protein-coupled receptor 144 [Homo sapiens]
          Length = 963

 Score = 72.0 bits (175), Expect = 9e-13
 Identities = 80/307 (26%), Positives = 123/307 (40%), Gaps = 44/307 (14%)

Query: 121 EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF 180
           EEES   T+     VG  +S  AL     + +        R  VH  L  TF L +   F
Sbjct: 653 EEESLLRTLSF---VGCGVSFCALTTTFLLFLVAGVPKSERTTVHKNL--TFSLASAEGF 707

Query: 181 LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR 240
           L  +    +++        V C     A HF  +  FSW+L E + L   + + S     
Sbjct: 708 LMTSEWAKANE--------VACVAVTVAMHFLFLVAFSWMLVEGLLLWRKVVAVSMHPGP 759

Query: 241 AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIA---CWDLDDTSPYWWIIKGPIVLSVGVNF 297
                   GWG+PV      ++  L  + +A   CW    T+  W  + GP++  +  N 
Sbjct: 760 GMRLYHATGWGVPVGIVAVTLAM-LPHDYVAPGHCWLNVHTNAIWAFV-GPVLFVLTANT 817

Query: 298 GLFLNIIRILV-------RKLEPAQGSLHTQ--SQYWRLSKSTLFLIPLFGIHYIIFNFL 348
            +   ++ I V       R L P Q  L  Q  +Q W   K  L L+P+ G+ ++     
Sbjct: 818 CILARVVMITVSSARRRARMLSP-QPCLQQQIWTQIWATVKPVLVLLPVLGLTWL----- 871

Query: 349 PDNAGLGIRLP-----LELGLGSFQGFIVAILYCFLNQEVRTEISRKWHGHDPELLPA-- 401
              AG+ + L        +GL S QG  + ++Y   N+EVR+ + R       E+L A  
Sbjct: 872 ---AGILVHLSPAWAYAAVGLNSIQGLYIFLVYAACNEEVRSALQRMAEKKVAEVLRALG 928

Query: 402 -WRTRAK 407
            W   AK
Sbjct: 929 VWGGAAK 935


>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
           sapiens]
          Length = 652

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 71/285 (24%), Positives = 118/285 (41%), Gaps = 22/285 (7%)

Query: 114 VPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFI 173
           V + L ++EE    TV  I  VG S+S++ L +A    +  + +      +H QL     
Sbjct: 343 VLMALTSQEEDPVLTV--ITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLF 400

Query: 174 LKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL-----N 228
           L A  +FL        D T+      VLC +   A H+  +  F+W+L E V+L     N
Sbjct: 401 L-AHLLFLVGI-----DRTE----PKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARN 450

Query: 229 CLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIA--CWDLDDTSPYWWIIK 286
             + + S  +R   W +   G+G+P +      +        A  CW L     + W   
Sbjct: 451 LTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCW-LHLDQGFMWSFL 509

Query: 287 GPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFN 346
           GP+      N  LF+ +  IL RKL      + T      L+      + + G  + +  
Sbjct: 510 GPVCAIFSANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCL-G 568

Query: 347 FLPDNAGLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKW 391
            L       +   L   + S QGF + ++YC L+Q+V+ +  +KW
Sbjct: 569 LLQVGPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQY-QKW 612


>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
          Length = 786

 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 58/265 (21%), Positives = 110/265 (41%), Gaps = 17/265 (6%)

Query: 131 IIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSD 190
           +I  VG ++S+  L + I   + +R +   R  +H  L     +         + +F + 
Sbjct: 500 LITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFV--------GSTIFLAG 551

Query: 191 DTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGW 250
             +      + C++     H+  +  F W+  E + L  L+         +  WL L G+
Sbjct: 552 IENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGY 611

Query: 251 GLPVLFTGTWVSCKLAFEDIA----CWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRI 306
           G+P+L  G  VS  +  +       CW LD    + W   GP+   +  N  +F+  +  
Sbjct: 612 GVPLLIVG--VSAAIYSKGYGRPRYCW-LDFEQGFLWSFLGPVTFIILCNAVIFVTTVWK 668

Query: 307 LVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGS 366
           L +K       +    +   L+ + +  + L G  ++   F+ D+  L +     + L  
Sbjct: 669 LTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTI-LNC 727

Query: 367 FQGFIVAILYCFLNQEVRTEISRKW 391
            QG  + +L+C LN++VR E  RKW
Sbjct: 728 LQGAFLYLLHCLLNKKVREEY-RKW 751


>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
          Length = 742

 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 58/265 (21%), Positives = 110/265 (41%), Gaps = 17/265 (6%)

Query: 131 IIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSD 190
           +I  VG ++S+  L + I   + +R +   R  +H  L     +         + +F + 
Sbjct: 456 LITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFV--------GSTIFLAG 507

Query: 191 DTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGW 250
             +      + C++     H+  +  F W+  E + L  L+         +  WL L G+
Sbjct: 508 IENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGY 567

Query: 251 GLPVLFTGTWVSCKLAFEDIA----CWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRI 306
           G+P+L  G  VS  +  +       CW LD    + W   GP+   +  N  +F+  +  
Sbjct: 568 GVPLLIVG--VSAAIYSKGYGRPRYCW-LDFEQGFLWSFLGPVTFIILCNAVIFVTTVWK 624

Query: 307 LVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGS 366
           L +K       +    +   L+ + +  + L G  ++   F+ D+  L +     + L  
Sbjct: 625 LTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTI-LNC 683

Query: 367 FQGFIVAILYCFLNQEVRTEISRKW 391
            QG  + +L+C LN++VR E  RKW
Sbjct: 684 LQGAFLYLLHCLLNKKVREEY-RKW 707


>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
          Length = 835

 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 58/265 (21%), Positives = 110/265 (41%), Gaps = 17/265 (6%)

Query: 131 IIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSD 190
           +I  VG ++S+  L + I   + +R +   R  +H  L     +         + +F + 
Sbjct: 549 LITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFV--------GSTIFLAG 600

Query: 191 DTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGW 250
             +      + C++     H+  +  F W+  E + L  L+         +  WL L G+
Sbjct: 601 IENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGY 660

Query: 251 GLPVLFTGTWVSCKLAFEDIA----CWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRI 306
           G+P+L  G  VS  +  +       CW LD    + W   GP+   +  N  +F+  +  
Sbjct: 661 GVPLLIVG--VSAAIYSKGYGRPRYCW-LDFEQGFLWSFLGPVTFIILCNAVIFVTTVWK 717

Query: 307 LVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGS 366
           L +K       +    +   L+ + +  + L G  ++   F+ D+  L +     + L  
Sbjct: 718 LTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTI-LNC 776

Query: 367 FQGFIVAILYCFLNQEVRTEISRKW 391
            QG  + +L+C LN++VR E  RKW
Sbjct: 777 LQGAFLYLLHCLLNKKVREEY-RKW 800


>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
          Length = 1474

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 72/285 (25%), Positives = 114/285 (40%), Gaps = 31/285 (10%)

Query: 118  LLAEEESYFSTVK-----IIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTF 172
            L+A  E Y   +      +I  VG  IS+V L + I+    LR L   RN +H  L    
Sbjct: 844  LMAHREIYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINL 903

Query: 173  ILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLA 232
             L A  +FL        D T +     + C +     H+  +  FSWL  E V+L  LL 
Sbjct: 904  FL-AELLFLVGI-----DKTQY----EIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLV 953

Query: 233  STSPSSRRAFWWLVLAGWGLPVLFTG--TWVSCKLAFEDIACWDLDDTSPYWWIIKGPIV 290
                S      +  L G+  P L  G    +  +    + ACW L   + + W   GP+ 
Sbjct: 954  EVFESEYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACW-LRVDNYFIWSFIGPVS 1012

Query: 291  LSVGVNFGLFLNIIRILVRK---LEPAQGSLHTQSQYWRLSKSTLFLIPL---FGIHYII 344
              + VN    +  +  ++R    L+P    L     +   + + LFL+ L   FG+ +I 
Sbjct: 1013 FVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFI- 1071

Query: 345  FNFLPDNAGLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISR 389
                  N    +   L     +FQG  + + +C L ++V  E S+
Sbjct: 1072 ------NKESVVMAYLFTTFNAFQGVFIFVFHCALQKKVHKEYSK 1110


>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
          Length = 1469

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 72/285 (25%), Positives = 114/285 (40%), Gaps = 31/285 (10%)

Query: 118  LLAEEESYFSTVK-----IIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTF 172
            L+A  E Y   +      +I  VG  IS+V L + I+    LR L   RN +H  L    
Sbjct: 839  LMAHREIYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINL 898

Query: 173  ILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLA 232
             L A  +FL        D T +     + C +     H+  +  FSWL  E V+L  LL 
Sbjct: 899  FL-AELLFLVGI-----DKTQY----EIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLV 948

Query: 233  STSPSSRRAFWWLVLAGWGLPVLFTG--TWVSCKLAFEDIACWDLDDTSPYWWIIKGPIV 290
                S      +  L G+  P L  G    +  +    + ACW L   + + W   GP+ 
Sbjct: 949  EVFESEYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACW-LRVDNYFIWSFIGPVS 1007

Query: 291  LSVGVNFGLFLNIIRILVRK---LEPAQGSLHTQSQYWRLSKSTLFLIPL---FGIHYII 344
              + VN    +  +  ++R    L+P    L     +   + + LFL+ L   FG+ +I 
Sbjct: 1008 FVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFI- 1066

Query: 345  FNFLPDNAGLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISR 389
                  N    +   L     +FQG  + + +C L ++V  E S+
Sbjct: 1067 ------NKESVVMAYLFTTFNAFQGVFIFVFHCALQKKVHKEYSK 1105


>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
            sapiens]
          Length = 3014

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 72/308 (23%), Positives = 115/308 (37%), Gaps = 32/308 (10%)

Query: 114  VPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFI 173
            V +++   E      +KI+     S+S+ AL VA  +L  +R L    + +H  L     
Sbjct: 2453 VLMDISRRENGEVLPLKIVTYAAVSLSLAALLVAFVLLSLVRMLRSNLHSIHKHL----- 2507

Query: 174  LKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLAS 233
              A A+FL         +     F   LC V     H+  M+ F+W L E++++  +L  
Sbjct: 2508 --AVALFLSQLVFVIGINQTENPF---LCTVVAILLHYIYMSTFAWTLVESLHVYRMLTE 2562

Query: 234  TSPSSRRAFWWLVLAGWGLPVLFTGTWVSCK---LAFEDIACWDLDDTSPYWWIIKGPIV 290
                      +  + GWG+P + TG  V          D     L DT    W   GPI 
Sbjct: 2563 VRNIDTGPMRFYYVVGWGIPAIVTGLAVGLDPQGYGNPDFCWLSLQDT--LIWSFAGPIG 2620

Query: 291  LSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYW------RLSKSTLFLIPLFGIHYII 344
              + +N           V  +  A+ S   +  Y+       L ++   L+ L    +++
Sbjct: 2621 AVIIIN----------TVTSVLSAKVSCQRKHHYYGKKGIVSLLRTAFLLLLLISATWLL 2670

Query: 345  FNFLPDNAGLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKWHGHDPELLPAWRT 404
                 +   L       +  G  QG  V + +C LNQEVR  +     G    L  +  T
Sbjct: 2671 GLLAVNRDALSFHYLFAIFSG-LQGPFVLLFHCVLNQEVRKHLKGVLGGRKLHLEDSATT 2729

Query: 405  RAKWTTPS 412
            RA   T S
Sbjct: 2730 RATLLTRS 2737



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 15/51 (29%), Positives = 21/51 (41%), Gaps = 5/51 (9%)

Query: 54   GCPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEP 104
            GCP  ++  + WP    G+   +PCP       S   AV+      GW  P
Sbjct: 2054 GCPKAFEAGIWWPQTKFGQPAAVPCPK-----GSVGNAVRHCSGEKGWLPP 2099


>gi|163792198 latrophilin 3 precursor [Homo sapiens]
          Length = 1469

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 76/281 (27%), Positives = 115/281 (40%), Gaps = 35/281 (12%)

Query: 131  IIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSD 190
            +I  VG  +S+V L + I      R L   RN +H  L  +  + A  +FL        +
Sbjct: 879  VITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFV-AELLFL-----IGIN 932

Query: 191  DTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLAST--SPSSRRAFWWLVLA 248
             TD      + C V  A  HF  +  F+W+  E V L  +L     S  SRR +++LV  
Sbjct: 933  RTDQ----PIACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLV-- 986

Query: 249  GWGLPVLFTGTWVSCKLAFE----DIACWDLDDTSPYWWIIKGPIVLSVGVN---FGLFL 301
            G+G+P L     VS  + +     D  CW   DT   W  I GP  L + +N    G+ L
Sbjct: 987  GYGMPALIVA--VSAAVDYRSYGTDKVCWLRLDTYFIWSFI-GPATLIIMLNVIFLGIAL 1043

Query: 302  NIIRILVRKLEPAQGSLHTQS--------QYWRLSKSTLFLIPLFGIHYIIFNFLPDNAG 353
              +      L+P  G L   +        + W +    + L+ L G+ +  F  +  N  
Sbjct: 1044 YKMFHHTAILKPESGCLDNINYEDNRPFIKSWVI--GAIALLCLLGLTW-AFGLMYINES 1100

Query: 354  LGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKWHGH 394
              I   L     S QG  + I +C L ++VR E  +    H
Sbjct: 1101 TVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTH 1141


>gi|23397681 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform a [Homo sapiens]
          Length = 823

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 75/330 (22%), Positives = 127/330 (38%), Gaps = 35/330 (10%)

Query: 69  GSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFST 128
           G G W T  C    +    ++  + R   ++ ++     Y V          +EE    T
Sbjct: 491 GCGHWATTGCSTIGTR---DTSTICRCTHLSSFAVLMAHYDV----------QEEDPVLT 537

Query: 129 VKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFH 188
           V  I  +G S+S++ L +A    +  + +      +H QL     L A  +FL       
Sbjct: 538 V--ITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFL-AHLLFLVAI---- 590

Query: 189 SDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYL-----NCLLASTSPSSRRAFW 243
            D T H     VLC +     H+  +   +W+L EA+YL     N  + + S  +R    
Sbjct: 591 -DQTGH----KVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKK 645

Query: 244 WLVLAGWGLPVLFTGTWVSCK--LAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFL 301
            +   G+G+P +      + +  L      CW L     + W   GP+     VN  LFL
Sbjct: 646 LMFPVGYGVPAVTVAISAASRPHLYGTPSRCW-LQPEKGFIWGFLGPVCAIFSVNLVLFL 704

Query: 302 NIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLE 361
             + IL  +L      + T      L+      + + G  + +   L       +   L 
Sbjct: 705 VTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCL-GILQVGPAARVMAYLF 763

Query: 362 LGLGSFQGFIVAILYCFLNQEVRTEISRKW 391
             + S QG  + ++YC L+Q+VR +   KW
Sbjct: 764 TIINSLQGVFIFLVYCLLSQQVREQYG-KW 792


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.470 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,194,447
Number of Sequences: 37866
Number of extensions: 807506
Number of successful extensions: 2497
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 56
Number of HSP's that attempted gapping in prelim test: 2292
Number of HSP's gapped (non-prelim): 117
length of query: 423
length of database: 18,247,518
effective HSP length: 105
effective length of query: 318
effective length of database: 14,271,588
effective search space: 4538364984
effective search space used: 4538364984
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.