Guide to the Human Genome
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Name: CYP46A1 Sequence: fasta or formatted (500aa) NCBI GI: 5729796
Description:

cytochrome P450, family 46

Referenced in:

Bile Acids and Other Cholesterol Derivatives
Cytochrome P450 Enzymes

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.4         32           2
 C cysteine            1.4          7           2
 D aspartate           4.2         21           2
 E glutamate           7.0         35           3
 F phenylalanine       6.0         30           2
 G glycine             6.8         34           2
 H histidine           1.6          8           1
 I isoleucine          2.8         14           1
 K lysine              5.4         27           2
 L leucine            12.6         63           4
 M methionine          3.0         15           1
 N asparagine          1.8          9           1
 P proline             6.6         33           5
 Q glutamine           5.2         26           2
 R arginine            7.8         39           3
 S serine              5.4         27           2
 T threonine           5.0         25           1
 V valine              7.4         37           2
 W tryptophan          1.2          6           1
 Y tyrosine            2.4         12           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   cytochrome P450, family 46 
CYP3A4                0.123   cytochrome P450, family 3, subfamily A, polypeptide ...
CYP4V2                0.119   cytochrome P450, family 4, subfamily v, polypeptide...
CYP3A5                0.119   cytochrome P450, family 3, subfamily A, polypeptide 5...
CYP4F3                0.118   cytochrome P450, family 4, subfamily F, polypeptide...
CYP3A7                0.117   cytochrome P450, family 3, subfamily A, polypeptide 7...
CYP4F22               0.115   cytochrome P450, family 4, subfamily F, polypeptide...
CYP4F8                0.113   cytochrome P450, family 4, subfamily F, polypeptide 8...
CYP4F12               0.112   cytochrome P450, family 4, subfamily F, polypeptide...
CYP4F2                0.111   cytochrome P450, family 4, subfamily F, polypeptide ...
CYP3A43               0.105   cytochrome P450, family 3, subfamily A, polypeptide ...
CYP4B1                0.101   cytochrome P450, family 4, subfamily B, polypeptide...
CYP4B1                0.101   cytochrome P450, family 4, subfamily B, polypeptide...
CYP3A43               0.101   cytochrome P450, family 3, subfamily A, polypeptide ...
CYP4F11               0.101   cytochrome P450 family 4 subfamily F polypeptide 11...
CYP4F11               0.101   cytochrome P450 family 4 subfamily F polypeptide 11...
TBXAS1                0.096   thromboxane A synthase 1, platelet isoform TXS-I [H...
TBXAS1                0.096   thromboxane A synthase 1, platelet isoform TXS-I [H...
CYP4Z1                0.093   cytochrome P450 4Z1 
CYP4X1                0.093   cytochrome P450, family 4, subfamily X, polypeptide ...
CYP2J2                0.090   cytochrome P450, family 2, subfamily J, polypeptide ...
CYP4A11               0.088   cytochrome P450, family 4, subfamily A, polypeptide...
CYP27B1               0.087   cytochrome P450, family 27, subfamily B, polypeptide ...
CYP4A22               0.086   cytochrome P450, family 4, subfamily A, polypeptide ...
CYP27A1               0.083   cytochrome P450, family 27, subfamily A, polypeptide ...
CYP2B6                0.082   cytochrome P450, family 2, subfamily B, polypeptide 6...
CYP24A1               0.080   cytochrome P450 family 24 subfamily A polypeptide 1 ...
CYP2A6                0.079   cytochrome P450, family 2, subfamily A, polypeptide...
CYP3A43               0.079   cytochrome P450, family 3, subfamily A, polypeptide ...
CYP2U1                0.076   cytochrome P450, family 2, subfamily U, polypeptide ...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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