Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 56118221
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56118221 amyloid beta (A4) precursor protein-binding, family
B, member 1 interacting protein [Homo sapiens]
(666 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56118221 amyloid beta (A4) precursor protein-binding, family ... 1378 0.0
gi|47132519 Ras association and pleckstrin homology domains 1 is... 482 e-136
gi|42740893 Ras association and pleckstrin homology domains 1 is... 418 e-117
gi|71979663 growth factor receptor-bound protein 14 [Homo sapiens] 172 9e-43
gi|48762679 growth factor receptor-bound protein 10 isoform a [H... 160 4e-39
gi|48762697 growth factor receptor-bound protein 10 isoform c [H... 159 1e-38
gi|48762695 growth factor receptor-bound protein 10 isoform c [H... 159 1e-38
gi|71979665 growth factor receptor-bound protein 7 [Homo sapiens] 142 1e-33
gi|71979667 growth factor receptor-bound protein 7 [Homo sapiens] 142 1e-33
gi|153792074 proline rich 12 [Homo sapiens] 99 1e-20
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 95 2e-19
gi|160707881 formin 2 [Homo sapiens] 94 3e-19
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 90 8e-18
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 90 8e-18
gi|210032580 SET domain containing 1B [Homo sapiens] 87 6e-17
gi|150417989 cyclin K isoform 1 [Homo sapiens] 84 4e-16
gi|11386183 WAS protein family, member 2 [Homo sapiens] 83 7e-16
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 80 5e-15
gi|157168329 formin 1 [Homo sapiens] 79 1e-14
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 79 1e-14
gi|52485606 formin-like 2 [Homo sapiens] 79 2e-14
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 79 2e-14
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 76 9e-14
gi|7706501 WW domain binding protein 11 [Homo sapiens] 76 1e-13
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho... 75 1e-13
gi|33356148 formin-like 1 [Homo sapiens] 75 2e-13
gi|48762693 growth factor receptor-bound protein 10 isoform b [H... 75 3e-13
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 75 3e-13
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 75 3e-13
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 74 4e-13
>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
member 1 interacting protein [Homo sapiens]
Length = 666
Score = 1378 bits (3567), Expect = 0.0
Identities = 666/666 (100%), Positives = 666/666 (100%)
Query: 1 MGESSEDIDQMFSTLLGEMDLLTQSLGVDTLPPPDPNPPRAEFNYSVGFKDLNESLNALE 60
MGESSEDIDQMFSTLLGEMDLLTQSLGVDTLPPPDPNPPRAEFNYSVGFKDLNESLNALE
Sbjct: 1 MGESSEDIDQMFSTLLGEMDLLTQSLGVDTLPPPDPNPPRAEFNYSVGFKDLNESLNALE 60
Query: 61 DQDLDALMADLVADISEAEQRTIQAQKESLQNQHHSASLQASIFSGAASLGYGTNVAATG 120
DQDLDALMADLVADISEAEQRTIQAQKESLQNQHHSASLQASIFSGAASLGYGTNVAATG
Sbjct: 61 DQDLDALMADLVADISEAEQRTIQAQKESLQNQHHSASLQASIFSGAASLGYGTNVAATG 120
Query: 121 ISQYEDDLPPPPADPVLDLPLPPPPPEPLSQEEEEAQAKADKIKLALEKLKEAKVKKLVV 180
ISQYEDDLPPPPADPVLDLPLPPPPPEPLSQEEEEAQAKADKIKLALEKLKEAKVKKLVV
Sbjct: 121 ISQYEDDLPPPPADPVLDLPLPPPPPEPLSQEEEEAQAKADKIKLALEKLKEAKVKKLVV 180
Query: 181 KVHMNDNSTKSLMVDERQLARDVLDNLFEKTHCDCNVDWCLYEIYPELQIERFFEDHENV 240
KVHMNDNSTKSLMVDERQLARDVLDNLFEKTHCDCNVDWCLYEIYPELQIERFFEDHENV
Sbjct: 181 KVHMNDNSTKSLMVDERQLARDVLDNLFEKTHCDCNVDWCLYEIYPELQIERFFEDHENV 240
Query: 241 VEVLSDWTRDTENKILFLEKEEKYAVFKNPQNFYLDNRGKKESKETNEKMNAKNKESLLE 300
VEVLSDWTRDTENKILFLEKEEKYAVFKNPQNFYLDNRGKKESKETNEKMNAKNKESLLE
Sbjct: 241 VEVLSDWTRDTENKILFLEKEEKYAVFKNPQNFYLDNRGKKESKETNEKMNAKNKESLLE 300
Query: 301 ESFCGTSIIVPELEGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFE 360
ESFCGTSIIVPELEGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFE
Sbjct: 301 ESFCGTSIIVPELEGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFE 360
Query: 361 NVNIYYGTQHKMKYKAPTDYCFVLKHPQIQKESQYIKYLCCDDTRTLNQWVMGIRIAKYG 420
NVNIYYGTQHKMKYKAPTDYCFVLKHPQIQKESQYIKYLCCDDTRTLNQWVMGIRIAKYG
Sbjct: 361 NVNIYYGTQHKMKYKAPTDYCFVLKHPQIQKESQYIKYLCCDDTRTLNQWVMGIRIAKYG 420
Query: 421 KTLYDNYQRAVAKAGLASRWTNLGTVNAAAPAQPSTGPKTGTTQPNGQIPQATHSVSAVL 480
KTLYDNYQRAVAKAGLASRWTNLGTVNAAAPAQPSTGPKTGTTQPNGQIPQATHSVSAVL
Sbjct: 421 KTLYDNYQRAVAKAGLASRWTNLGTVNAAAPAQPSTGPKTGTTQPNGQIPQATHSVSAVL 480
Query: 481 QEAQRHAETSKDKKPALGNHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKG 540
QEAQRHAETSKDKKPALGNHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKG
Sbjct: 481 QEAQRHAETSKDKKPALGNHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKG 540
Query: 541 TGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPP 600
TGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPP
Sbjct: 541 TGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPP 600
Query: 601 PPPPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGAGGGEQDFMSDLMKALQK 660
PPPPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGAGGGEQDFMSDLMKALQK
Sbjct: 601 PPPPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGAGGGEQDFMSDLMKALQK 660
Query: 661 KRGNVS 666
KRGNVS
Sbjct: 661 KRGNVS 666
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 482 bits (1240), Expect = e-136
Identities = 276/649 (42%), Positives = 372/649 (57%), Gaps = 90/649 (13%)
Query: 63 DLDALMADLVADISEAEQRTIQAQKESLQNQHHSASLQASIFSGAA--SLGYGTNVAATG 120
D+ A + + EA Q+++ + L H + A S A S+ ++ + T
Sbjct: 155 DVTAQLEQASLSMDEAAQQSVLEDTKPLVTNQHRRTASAGTVSDAEVHSISNSSHSSITS 214
Query: 121 ISQYEDDLPPPPADPVLDLPLPPPPPEPLSQEEEEAQAKADKIKLALEKLKEAKVKKLVV 180
+ D L +L L +P+++EE+ A+ KA+KI++ALEK+KEA+VKKLV+
Sbjct: 215 AASSMDSLDIDKVTRPQELDLTHQG-QPITEEEQAAKLKAEKIRVALEKIKEAQVKKLVI 273
Query: 181 KVHMNDNSTKSLMVDERQLARDVLDNLFEKTHCDCNVDWCLYEIYPELQIERFFEDHENV 240
+VHM+D+S+K++MVDERQ R VLDNL +K+HC ++DW L E ELQ+ER FEDHEN+
Sbjct: 274 RVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETVSELQMERIFEDHENL 333
Query: 241 VEVLSDWTRDTENKILFLEKEEKYAVFKNPQNFYLDNRGKKESKETNEKMNAKNKESLLE 300
VE L +WTRD++NK++F+E+ EKYA+FKNPQN+ L GKKE+ E M +NKE LLE
Sbjct: 334 VENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLL---GKKETAE----MADRNKEVLLE 386
Query: 301 ESFCGTSIIVPELEGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFE 360
E FCG+S+ VPE+EG L+LK+DGKKSWK+RYFLLRASGIYYVPKGK K SRDL CF+Q +
Sbjct: 387 ECFCGSSVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLD 446
Query: 361 NVNIYYGTQHKMKYKAPTDYCFVLKHPQIQKESQYIKYLCCDDTRTLNQWVMGIRIAKYG 420
+VN+YYG ++ KYKAPTDYC VLKHPQIQK+SQYIKYLCCDD RTL+QWV GIRIAKYG
Sbjct: 447 HVNVYYGQDYRNKYKAPTDYCLVLKHPQIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKYG 506
Query: 421 KTLYDNYQRAVAKAGLASRWTNLGTVNAAAPAQPSTGPKT------------GTTQPNGQ 468
K LY NYQ A+ + A WT+L + + + + S+ P++ TQP G
Sbjct: 507 KQLYMNYQEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGH 566
Query: 469 IPQATHSVSAVLQEAQRHA----ETSKDK----------------------KPALGNHHD 502
+ ++ VS+V EA + E+SK + P +
Sbjct: 567 V-RSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPS 625
Query: 503 PAVPRAPHAPKSSLPPPPP----------------------------VRRSSDTSGS--- 531
P +P P P PPPPP ++ +S SG+
Sbjct: 626 PPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFK 685
Query: 532 -PATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDP-----ELPPPPPDFMEPPPDFVPP 585
P P+ + + PP+ +PPPPPPPP P +L P P P F P
Sbjct: 686 PPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAP--CAPSLPQFSAP 743
Query: 586 PPPSYAGIAG--SELPPPPPPPPAPAPAPVPDSARPPPAVAKRPPVPPK 632
PPP +++ PP PPPP P PAP+P A P P V P K
Sbjct: 744 PPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTK 792
Score = 79.0 bits (193), Expect = 1e-14
Identities = 67/235 (28%), Positives = 91/235 (38%), Gaps = 59/235 (25%)
Query: 450 APAQPSTGPKTGTTQPNGQIPQATHSVSAVLQEAQRHAETSK----DKKPALGNHHDPAV 505
AP P PK T P P +T +V+ V+ +A T K+PA + P
Sbjct: 771 APLPPQAPPKPLVTIP---APTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS 827
Query: 506 PRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDD 565
P P P +PPP ++ S + P +PL + + + PPPP PP ++
Sbjct: 828 PPTPPVP---VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQ----FPPPPTPPAMES 880
Query: 566 -----------PELPP---------------PPPDFMEPPPD---FVPPPPPSYAGIAGS 596
P+ PP P PDF PPP+ PPPPPS
Sbjct: 881 QPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPV----- 935
Query: 597 ELPPPPPPPPAPAPAPVPDSARPP--------PAVAKRPPVPPKRQENPGHPGGA 643
P PPPPP P +P PD + P K+PP P+R + GA
Sbjct: 936 ---PAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGA 987
Score = 57.8 bits (138), Expect = 3e-08
Identities = 34/75 (45%), Positives = 42/75 (56%), Gaps = 6/75 (8%)
Query: 3 ESSEDIDQMFSTLLGEMDLLTQSLGVDTLPPPDPNPP------RAEFNYSVGFKDLNESL 56
+ +D+D+MF LGE+D LTQSL D P P A F+Y +LNE+L
Sbjct: 19 KEDQDLDKMFGAWLGELDKLTQSLDSDKPMEPVKRSPLRQETNMANFSYRFSIYNLNEAL 78
Query: 57 NALEDQDLDALMADL 71
N E DLDALMADL
Sbjct: 79 NQGETVDLDALMADL 93
Score = 57.0 bits (136), Expect = 5e-08
Identities = 62/230 (26%), Positives = 95/230 (41%), Gaps = 31/230 (13%)
Query: 455 STGPKTG-TTQPNGQIPQATHSVSAVLQEAQRHAETSKDKKPALGNHHDPAVPRAPHAP- 512
S G KT T+ P G+ P T ++ ++ + AE + K+P++ + P A
Sbjct: 955 SPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSG-AEHPEPKRPSVDSLVSKFTPPAESGSP 1013
Query: 513 -KSSLPPP--PPVRRSSDTSG--------SPATPLKAKGTGGGG------LPAPPDDFLP 555
K +LPPP PP + SG KA G G P+PP D
Sbjct: 1014 SKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDF 1073
Query: 556 PPPPP---PPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAP 612
PPPPP PL E+P P V P P ++ ++ + PPP P
Sbjct: 1074 PPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKR------ 1127
Query: 613 VPDSARPPPA-VAKRPPVPPKRQENPGHPGGAGGGEQDFMSDLMKALQKK 661
DS R A ++++P + + P P + + F++DL + LQ+K
Sbjct: 1128 -NDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRK 1176
Score = 37.4 bits (85), Expect = 0.045
Identities = 40/166 (24%), Positives = 60/166 (36%), Gaps = 39/166 (23%)
Query: 455 STGPKTGTTQPNGQ------IPQATHSVSAVLQEAQRHAETSKDKKPALGNHHDPAVPRA 508
+T PK P Q + +A ++ R + ++P + VP+
Sbjct: 1096 NTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMAT----VVPQV 1151
Query: 509 PHAPKSSLPPPPPVRRSSDTSGSPATPLKAKG-TGGGGLPAPPDDFLPPPPPPPPLDDPE 567
P +PKSSL P + + L+ K T G L + + P +DD
Sbjct: 1152 PTSPKSSLSVQPGFLADLNRT------LQRKSITRHGSLSSR----MSRAEPTATMDDMA 1201
Query: 568 LPPPPPDFMEPPPDFVPPPPPSYAGIAGSEL---------PPPPPP 604
LPPPPP+ + AG GS + PPP PP
Sbjct: 1202 LPPPPPELLS---------DQQKAGYGGSHISGYATLRRGPPPAPP 1238
Score = 32.3 bits (72), Expect = 1.4
Identities = 14/34 (41%), Positives = 16/34 (47%), Gaps = 3/34 (8%)
Query: 129 PPPPADPVLDLPLPPPPPEPLSQEEEEAQAKADK 162
PPPP PV P PPPPP P + + K
Sbjct: 928 PPPPPSPV---PAPPPPPPPTASPTPDKSGSPGK 958
Score = 31.2 bits (69), Expect = 3.2
Identities = 12/22 (54%), Positives = 13/22 (59%)
Query: 127 DLPPPPADPVLDLPLPPPPPEP 148
D PPPP + L P PPP P P
Sbjct: 915 DFPPPPPESSLVFPPPPPSPVP 936
>gi|42740893 Ras association and pleckstrin homology domains 1
isoform 3 [Homo sapiens]
Length = 644
Score = 418 bits (1074), Expect = e-117
Identities = 206/351 (58%), Positives = 267/351 (76%), Gaps = 20/351 (5%)
Query: 145 PPEPLSQEEEEAQAKADKIKLALEKLKEAKVKKLVVKVHMNDNSTKSLMVDERQLARDVL 204
P L++EE+ A+ KA+KI++ALEK+KEA+VKKLV++VHM+D+S+K++MVDERQ R VL
Sbjct: 290 PSHLLTKEEQAAKLKAEKIRVALEKIKEAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVL 349
Query: 205 DNLFEKTHCDCNVDWCLYEIYPELQIERFFEDHENVVEVLSDWTRDTENKILFLEKEEKY 264
DNL +K+HC ++DW L E ELQ+ER FEDHEN+VE L +WTRD++NK++F+E+ EKY
Sbjct: 350 DNLMDKSHCGYSLDWSLVETVSELQMERIFEDHENLVENLLNWTRDSQNKLIFMERIEKY 409
Query: 265 AVFKNPQNFYLDNRGKKESKETNEKMNAKNKESLLEESFCGTSIIVPELEGALYLKEDGK 324
A+FKNPQN+ L GKKE+ E M +NKE LLEE FCG+S+ VPE+EG L+LK+DGK
Sbjct: 410 ALFKNPQNYLL---GKKETAE----MADRNKEVLLEECFCGSSVTVPEIEGVLWLKDDGK 462
Query: 325 KSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFENVNIYYGTQHKMKYKAPTDYCFVL 384
KSWK+RYFLLRASGIYYVPKGK K SRDL CF+Q ++VN+YYG ++ KYKAPTDYC VL
Sbjct: 463 KSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDYCLVL 522
Query: 385 KHPQIQKESQYIKYLCCDDTRTLNQWVMGIRIAKYGKTLYDNYQRAVAKAGLASRWTNLG 444
KHPQIQK+SQYIKYLCCDD RTL+QWV GIRIAKYGK LY NYQ A+ + A WT+L
Sbjct: 523 KHPQIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKYGKQLYMNYQEALKRTESAYDWTSLS 582
Query: 445 TVNAAAPAQPSTGPKT------------GTTQPNGQIPQATHSVSAVLQEA 483
+ + + + S+ P++ TQP G + ++ VS+V EA
Sbjct: 583 SSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHV-RSQSIVSSVFSEA 632
Score = 57.8 bits (138), Expect = 3e-08
Identities = 34/75 (45%), Positives = 42/75 (56%), Gaps = 6/75 (8%)
Query: 3 ESSEDIDQMFSTLLGEMDLLTQSLGVDTLPPPDPNPP------RAEFNYSVGFKDLNESL 56
+ +D+D+MF LGE+D LTQSL D P P A F+Y +LNE+L
Sbjct: 19 KEDQDLDKMFGAWLGELDKLTQSLDSDKPMEPVKRSPLRQETNMANFSYRFSIYNLNEAL 78
Query: 57 NALEDQDLDALMADL 71
N E DLDALMADL
Sbjct: 79 NQGETVDLDALMADL 93
>gi|71979663 growth factor receptor-bound protein 14 [Homo sapiens]
Length = 540
Score = 172 bits (436), Expect = 9e-43
Identities = 106/294 (36%), Positives = 149/294 (50%), Gaps = 16/294 (5%)
Query: 137 LDLPLPPPPPEPLSQ---EEEEAQAKADKIKLALEKLKEAKVKKLVVKVHMNDNSTKSLM 193
LD+P P P P + + AD A + KK V+KV+ D ++++L
Sbjct: 70 LDVPEMPSIPNPFPELCCSPFTSVLSADLFPKANSR------KKQVIKVYSEDETSRALD 123
Query: 194 VDERQLARDVLDNLFEKTHCDCNVDWCLYEIYPELQIERFFEDHENVVEVLSDWTRDTEN 253
V ARDV L K H + W L+E P + +ER EDHE V+EVLS+W + EN
Sbjct: 124 VPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIEEEN 183
Query: 254 KILFLEKEEKYAVFKNPQNFYLDNRGKKESKETNEKMNAKNKESLLEESFCGTSIIVPEL 313
K+ F + KY FKNP F+ ++ ++ E + + L S PE+
Sbjct: 184 KLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSS------TYPEI 237
Query: 314 EGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFENVNIYYGTQHKMK 373
G L+ KE GKKSWK+ YF LR SG+Y+ KG +K R L F +F N +IY K K
Sbjct: 238 HGFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKK 297
Query: 374 YKAPTDYCFVLKHPQIQKESQYIKYLCCDDTRTLNQWVMGIRIAKYGKTLYDNY 427
+ APT+Y F K P + +K LC ++ ++ WV IR+ KYG LY NY
Sbjct: 298 HGAPTNYGFCFK-PNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNY 350
>gi|48762679 growth factor receptor-bound protein 10 isoform a [Homo
sapiens]
Length = 594
Score = 160 bits (405), Expect = 4e-39
Identities = 123/400 (30%), Positives = 185/400 (46%), Gaps = 50/400 (12%)
Query: 60 EDQDLDALMADLVADISEAEQRTIQAQKES---LQNQHHSAS----------LQASIFSG 106
+D DL+AL+ D+ A + E+ Q ++ LQN H+ S +Q +
Sbjct: 48 DDVDLEALVNDMNASL-ESLYSACSMQSDTVPLLQNGQHARSQPRASGPPRSIQPQVSPR 106
Query: 107 A-ASLGYGTNVAATGISQYEDDLPPPPADPVLDLPLP-------PPPPEPLSQEEEEAQA 158
++ A Q ED + P + P P PP P S +A A
Sbjct: 107 QRVQRSQPVHILAVRRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAA 166
Query: 159 KADKIKLALEKLKEAKVKKLVVKVHMNDNSTKSLMVDERQLARDVLDNLFEKTHCDCNVD 218
K D VKV D ++K + + ARD+ L K+HC +
Sbjct: 167 KQD------------------VKVFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDDNS 208
Query: 219 WCLYEIYPELQIERFFEDHENVVEVLSDWTRDTENKILFLEKEEKYAVFKNPQNFYLDNR 278
W L E +P L +ER EDHE VV+V S T +E+K LF + KY FKNP NF+
Sbjct: 209 WTLVEHHPHLGLERCLEDHELVVQVES--TMASESKFLFRKNYAKYEFFKNPMNFF---- 262
Query: 279 GKKESKETNEKMNAKNKESLLEESFCGTSIIVPELEGALYLKEDGKKSWKRRYFLLRASG 338
E T + + ++ LL+ +S PE++G L++KE GKKSWK+ Y LR SG
Sbjct: 263 --PEQMVTWCQQSNGSQTQLLQNFLNSSSC--PEIQGFLHVKELGKKSWKKLYVCLRRSG 318
Query: 339 IYYVPKGKTKTSRDLACFIQFENVNIYYGTQHKMKYKAPTDYCFVLKHPQIQKESQYIKY 398
+Y KG +K R L E+ NI+ + +Y APTD+ +K +++ E++ ++
Sbjct: 319 LYCSTKGTSKEPRHLQLLADLEDSNIFSLIAGRKQYNAPTDHGLCIKPNKVRNETKELRL 378
Query: 399 LCCDDTRTLNQWVMGIRIAKYGKTLYDNYQRAVAKAGLAS 438
LC +D +T W+ R+ KYG LY NY+ + L S
Sbjct: 379 LCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIPQQRKALLS 418
>gi|48762697 growth factor receptor-bound protein 10 isoform c [Homo
sapiens]
Length = 536
Score = 159 bits (401), Expect = 1e-38
Identities = 105/308 (34%), Positives = 152/308 (49%), Gaps = 28/308 (9%)
Query: 131 PPADPVLDLPLPPPPPEPLSQEEEEAQAKADKIKLALEKLKEAKVKKLVVKVHMNDNSTK 190
P P L P PP P S +A AK D VKV D ++K
Sbjct: 81 PNPFPELCGPGSPPVLTPGSLPPSQAAAKQD------------------VKVFSEDGTSK 122
Query: 191 SLMVDERQLARDVLDNLFEKTHCDCNVDWCLYEIYPELQIERFFEDHENVVEVLSDWTRD 250
+ + ARD+ L K+HC + W L E +P L +ER EDHE VV+V S T
Sbjct: 123 VVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVES--TMA 180
Query: 251 TENKILFLEKEEKYAVFKNPQNFYLDNRGKKESKETNEKMNAKNKESLLEESFCGTSIIV 310
+E+K LF + KY FKNP NF+ E T + + ++ LL+ +S
Sbjct: 181 SESKFLFRKNYAKYEFFKNPMNFF------PEQMVTWCQQSNGSQTQLLQNFLNSSSC-- 232
Query: 311 PELEGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFENVNIYYGTQH 370
PE++G L++KE GKKSWK+ Y LR SG+Y KG +K R L E+ NI+
Sbjct: 233 PEIQGFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFSLIAG 292
Query: 371 KMKYKAPTDYCFVLKHPQIQKESQYIKYLCCDDTRTLNQWVMGIRIAKYGKTLYDNYQRA 430
+ +Y APTD+ +K +++ E++ ++ LC +D +T W+ R+ KYG LY NY+
Sbjct: 293 RKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIP 352
Query: 431 VAKAGLAS 438
+ L S
Sbjct: 353 QQRKALLS 360
>gi|48762695 growth factor receptor-bound protein 10 isoform c [Homo
sapiens]
Length = 536
Score = 159 bits (401), Expect = 1e-38
Identities = 105/308 (34%), Positives = 152/308 (49%), Gaps = 28/308 (9%)
Query: 131 PPADPVLDLPLPPPPPEPLSQEEEEAQAKADKIKLALEKLKEAKVKKLVVKVHMNDNSTK 190
P P L P PP P S +A AK D VKV D ++K
Sbjct: 81 PNPFPELCGPGSPPVLTPGSLPPSQAAAKQD------------------VKVFSEDGTSK 122
Query: 191 SLMVDERQLARDVLDNLFEKTHCDCNVDWCLYEIYPELQIERFFEDHENVVEVLSDWTRD 250
+ + ARD+ L K+HC + W L E +P L +ER EDHE VV+V S T
Sbjct: 123 VVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVES--TMA 180
Query: 251 TENKILFLEKEEKYAVFKNPQNFYLDNRGKKESKETNEKMNAKNKESLLEESFCGTSIIV 310
+E+K LF + KY FKNP NF+ E T + + ++ LL+ +S
Sbjct: 181 SESKFLFRKNYAKYEFFKNPMNFF------PEQMVTWCQQSNGSQTQLLQNFLNSSSC-- 232
Query: 311 PELEGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFENVNIYYGTQH 370
PE++G L++KE GKKSWK+ Y LR SG+Y KG +K R L E+ NI+
Sbjct: 233 PEIQGFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFSLIAG 292
Query: 371 KMKYKAPTDYCFVLKHPQIQKESQYIKYLCCDDTRTLNQWVMGIRIAKYGKTLYDNYQRA 430
+ +Y APTD+ +K +++ E++ ++ LC +D +T W+ R+ KYG LY NY+
Sbjct: 293 RKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIP 352
Query: 431 VAKAGLAS 438
+ L S
Sbjct: 353 QQRKALLS 360
>gi|71979665 growth factor receptor-bound protein 7 [Homo sapiens]
Length = 532
Score = 142 bits (357), Expect = 1e-33
Identities = 80/255 (31%), Positives = 132/255 (51%), Gaps = 5/255 (1%)
Query: 179 VVKVHMNDNSTKSLMVDERQLARDVLDNLFEKTHCDCNVDWCLYEIYPELQIERFFEDHE 238
VVKV+ D + +S+ V AR V + L ++ H + W L E +P L +ER EDHE
Sbjct: 103 VVKVYSEDGACRSVEVAAGATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHE 162
Query: 239 NVVEVLSDWTRDTENKILFLEKEEKYAVFKNPQNFYLDNRGKKESKETNEKMNAKNKESL 298
+VVEV + W +++ +F + KY +FK+ + + + + ++ E L
Sbjct: 163 SVVEVQAAWPVGGDSRFVFRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGIS---HEDL 219
Query: 299 LEESFCGTSIIVPELEGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQ 358
++ S PE++G L L+ G+K WKR + LR SG+YY KG +K R L
Sbjct: 220 IQNFLNAGSF--PEIQGFLQLRGSGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVAD 277
Query: 359 FENVNIYYGTQHKMKYKAPTDYCFVLKHPQIQKESQYIKYLCCDDTRTLNQWVMGIRIAK 418
N+Y TQ + Y PTD+ F +K +++ + ++ C +D ++ W+ R+ K
Sbjct: 278 VNESNVYVVTQGRKLYGMPTDFGFCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFK 337
Query: 419 YGKTLYDNYQRAVAK 433
YG LY NYQ+A ++
Sbjct: 338 YGVQLYKNYQQAQSR 352
Score = 29.6 bits (65), Expect = 9.4
Identities = 28/94 (29%), Positives = 36/94 (38%), Gaps = 10/94 (10%)
Query: 546 LPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSY--AGIAGSELPPPPP 603
L + P+D P P PP P P P + P +P + LP P
Sbjct: 10 LSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTTGRKLREEERRATSLPSIPN 69
Query: 604 PPP----APAPAPV---PDSARP-PPAVAKRPPV 629
P P P+ +P+ P SAR P A RP V
Sbjct: 70 PFPELCSPPSQSPILGGPSSARGLLPRDASRPHV 103
>gi|71979667 growth factor receptor-bound protein 7 [Homo sapiens]
Length = 532
Score = 142 bits (357), Expect = 1e-33
Identities = 80/255 (31%), Positives = 132/255 (51%), Gaps = 5/255 (1%)
Query: 179 VVKVHMNDNSTKSLMVDERQLARDVLDNLFEKTHCDCNVDWCLYEIYPELQIERFFEDHE 238
VVKV+ D + +S+ V AR V + L ++ H + W L E +P L +ER EDHE
Sbjct: 103 VVKVYSEDGACRSVEVAAGATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHE 162
Query: 239 NVVEVLSDWTRDTENKILFLEKEEKYAVFKNPQNFYLDNRGKKESKETNEKMNAKNKESL 298
+VVEV + W +++ +F + KY +FK+ + + + + ++ E L
Sbjct: 163 SVVEVQAAWPVGGDSRFVFRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGIS---HEDL 219
Query: 299 LEESFCGTSIIVPELEGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQ 358
++ S PE++G L L+ G+K WKR + LR SG+YY KG +K R L
Sbjct: 220 IQNFLNAGSF--PEIQGFLQLRGSGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVAD 277
Query: 359 FENVNIYYGTQHKMKYKAPTDYCFVLKHPQIQKESQYIKYLCCDDTRTLNQWVMGIRIAK 418
N+Y TQ + Y PTD+ F +K +++ + ++ C +D ++ W+ R+ K
Sbjct: 278 VNESNVYVVTQGRKLYGMPTDFGFCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFK 337
Query: 419 YGKTLYDNYQRAVAK 433
YG LY NYQ+A ++
Sbjct: 338 YGVQLYKNYQQAQSR 352
Score = 29.6 bits (65), Expect = 9.4
Identities = 28/94 (29%), Positives = 36/94 (38%), Gaps = 10/94 (10%)
Query: 546 LPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSY--AGIAGSELPPPPP 603
L + P+D P P PP P P P + P +P + LP P
Sbjct: 10 LSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTTGRKLREEERRATSLPSIPN 69
Query: 604 PPP----APAPAPV---PDSARP-PPAVAKRPPV 629
P P P+ +P+ P SAR P A RP V
Sbjct: 70 PFPELCSPPSQSPILGGPSSARGLLPRDASRPHV 103
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 99.0 bits (245), Expect = 1e-20
Identities = 69/188 (36%), Positives = 85/188 (45%), Gaps = 24/188 (12%)
Query: 480 LQEAQRHAETSKDKKPALGNHHDPAVPRAPHAPKSSLPPPPPVRR--SSDTSGSPATPLK 537
LQE+ A ++ D P G P AP +++P PPP+ S++++G+P PL
Sbjct: 1394 LQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLL 1453
Query: 538 AKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPP-----DFMEPPPDFVPPPPPSYAG 592
+ PAP PPPPPPPP P LP PPP PPP PPPPP
Sbjct: 1454 EEKPPPTPPPAPTPQPQPPPPPPPP--QPALPSPPPLVAPTPSSPPPPPLPPPPPP---- 1507
Query: 593 IAGSELPPPPPPPPAPAPAPVPDSARPPPAVAKRPPVPP----KRQENPGHPG------G 642
A PPPPPP AP AP + A P P + P P K+QE G G
Sbjct: 1508 -AMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAG 1566
Query: 643 AGGGEQDF 650
GGE F
Sbjct: 1567 ESGGEGIF 1574
Score = 54.7 bits (130), Expect = 3e-07
Identities = 58/198 (29%), Positives = 69/198 (34%), Gaps = 34/198 (17%)
Query: 457 GPKTGTTQPNGQIPQATHSVSAVLQEAQRHAETSKDKKPALGNHHDPAV------PRAPH 510
GP+ G P G H A +E + S P P P
Sbjct: 731 GPERGGETPEGLATSVVH-YGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPD 789
Query: 511 APKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPP 570
P LPPPPP S S +P+ A G L D P PPPPPP PP
Sbjct: 790 LPLV-LPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPP------PP 842
Query: 571 PPPDFME--------------PPPDFVP----PPPPSYAGIAGSELPPPPPPPPAPAPAP 612
PPP ++ P P P PP + + G+ L P PP P P
Sbjct: 843 PPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGA-LEPLPPAPGDTGVGP 901
Query: 613 VPDSARPPPAVAKRPPVP 630
P+S PA A R P P
Sbjct: 902 -PNSEGKDPAGAYRSPSP 918
Score = 53.9 bits (128), Expect = 5e-07
Identities = 46/163 (28%), Positives = 57/163 (34%), Gaps = 35/163 (21%)
Query: 524 RSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPE---------------- 567
R +T AT + G G L A PPPPP P
Sbjct: 734 RGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLV 793
Query: 568 LPPPPPDFMEPPPDFVPPPPPSYAGIA-----------GSELPPPPPPPPAPAPAPVPDS 616
LPPPPP + P P PS + + + PPPPPPPP P P +
Sbjct: 794 LPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAH 853
Query: 617 ARPPPAVAKRPPVPPKRQENPGHPGGAGGGEQDFMSDLMKALQ 659
R + P P R E P GA M +L+ AL+
Sbjct: 854 LR-SHGLEPAAPSPRLRPEESLDPPGA-------MQELLGALE 888
Score = 49.7 bits (117), Expect = 9e-06
Identities = 50/171 (29%), Positives = 64/171 (37%), Gaps = 37/171 (21%)
Query: 490 SKDKKPALGNHHDPAVPRAPHAPK----SSLPPPPPVRRSSDTSGSPATPLKAKGTGGG- 544
S+ K PA G + P+ P+ AP+ +S+ P + + + S P + GGG
Sbjct: 904 SEGKDPA-GAYRSPS-PQGTKAPRFVPLTSICFPDSLLQDEERSFFPTME---EMFGGGA 958
Query: 545 ----GLPAPPDDFLPP-----PPPPPPLDDPELPPPPPDFMEPPPD-----FVPPPPPSY 590
G PP+D P PPP PP DP P P P+ P PP
Sbjct: 959 ADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPEL 1018
Query: 591 AGIAGSEL-------------PPPPPPPPAPAPAPVPDSARPPPAVAKRPP 628
+E PPPPPPPP PAPA P P P
Sbjct: 1019 PSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKP 1069
Score = 39.3 bits (90), Expect = 0.012
Identities = 47/160 (29%), Positives = 56/160 (35%), Gaps = 32/160 (20%)
Query: 518 PPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPP---PPPD 574
PP PVRRS G P+ A GG P P PP P P E PP P
Sbjct: 1670 PPVPVRRS----GQAKNPVSA---GGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETA 1722
Query: 575 FMEPP----PDFVPP---------------PPPSYAGIAGSELPPPPP-PPPAPAPAPVP 614
EPP P + P P +G + P PA + +P
Sbjct: 1723 MPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLP 1782
Query: 615 DSARPPPAVAKRPPVPPKR-QENPGHPGGAGGGEQDFMSD 653
ARP A+ PP K+ + G AGGG SD
Sbjct: 1783 -KARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSD 1821
Score = 38.1 bits (87), Expect = 0.026
Identities = 37/122 (30%), Positives = 44/122 (36%), Gaps = 29/122 (23%)
Query: 529 SGSPATP--LKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDF---- 582
S +P P L + GGG+ P L P PP P PPPPP + P F
Sbjct: 194 SQAPTVPSSLGFERLAGGGVLGPAG--LGPAQTPPYRPGPPDPPPPPRHL--PTQFNLLA 249
Query: 583 --------VPPPPPSYAGIAGSELPPPPPPPPAPAPAPV------PDSARPPPAVAKRPP 628
P +G+ PPPP P V P SA+PPP PP
Sbjct: 250 SSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPP-----PP 304
Query: 629 VP 630
P
Sbjct: 305 PP 306
Score = 34.3 bits (77), Expect = 0.38
Identities = 31/97 (31%), Positives = 35/97 (36%), Gaps = 34/97 (35%)
Query: 542 GGGGLPAPPDDFLPPPPPPPPL---------------------DDPEL--------PPPP 572
G G PP PP PPPPP P+L PPP
Sbjct: 218 GLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPP 277
Query: 573 PDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPA 609
P+ P D V Y A ++ PPPPPPPA A
Sbjct: 278 PERALPRQDTVIK---HYQRPASAQ--PPPPPPPAHA 309
Score = 33.9 bits (76), Expect = 0.50
Identities = 23/76 (30%), Positives = 27/76 (35%), Gaps = 19/76 (25%)
Query: 556 PPPPPPPLDDPELPPP------PPDFMEPPPDFVPPPPPSY-------------AGIAGS 596
P P L DP PP P D + P P P S AG+ +
Sbjct: 163 PVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPA 222
Query: 597 ELPPPPPPPPAPAPAP 612
+ PP P PP P P P
Sbjct: 223 QTPPYRPGPPDPPPPP 238
Score = 33.5 bits (75), Expect = 0.65
Identities = 43/164 (26%), Positives = 54/164 (32%), Gaps = 37/164 (22%)
Query: 509 PHAPKSSLPPPPPVRRSSD---TSGSPATPLKAKGTG------GGGLPAPPDDFLPPPPP 559
P+ P PPPPP + + S A A+ + G P PP PP
Sbjct: 226 PYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPP----PPERA 281
Query: 560 PPPLDDPELPPPPPDFMEPPPDFVPPPPPSY------------------AGIAGSELPPP 601
P D P +PP PPPPP++ A +A S L
Sbjct: 282 LPRQDTVIKHYQRPASAQPP----PPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGG 337
Query: 602 PPPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGAGG 645
P P A P+ S A A P+ G GG GG
Sbjct: 338 EPSPGAGEPSKAGPSG--ATAGASGRATGPEAAGGGGAGGGGGG 379
Score = 32.3 bits (72), Expect = 1.4
Identities = 23/61 (37%), Positives = 23/61 (37%), Gaps = 10/61 (16%)
Query: 552 DFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPA 611
DFL PPL L PP PP VPP P A P PP P P P
Sbjct: 1287 DFLKSGKRHPPLYQAGLTPPLS-----PPKSVPPSVP-----ARGLQPQPPATPAVPHPP 1336
Query: 612 P 612
P
Sbjct: 1337 P 1337
Score = 30.8 bits (68), Expect = 4.2
Identities = 19/44 (43%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
Query: 116 VAATGISQYEDDLPPPPADPVLDLPLPPPP-PEPLSQEEEEAQA 158
VA T S LPPPP + P PPPP PL+ EE A
Sbjct: 1489 VAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAA 1532
Score = 29.6 bits (65), Expect = 9.4
Identities = 11/20 (55%), Positives = 12/20 (60%)
Query: 129 PPPPADPVLDLPLPPPPPEP 148
PPP P P PPPPP+P
Sbjct: 1461 PPPAPTPQPQPPPPPPPPQP 1480
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 94.7 bits (234), Expect = 2e-19
Identities = 53/131 (40%), Positives = 60/131 (45%), Gaps = 20/131 (15%)
Query: 496 ALGNHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLP 555
A+ N P P + PPPPP +S G P P + G G P PP P
Sbjct: 267 AVKNELRRQAPPPPPPSRGGPPPPPPPPHNS---GPPPPPAR-----GRGAPPPPPSRAP 318
Query: 556 ---PPPPPPPLDDPELPPPPPDFMEPPPDFV---------PPPPPSYAGIAGSELPPPPP 603
PPPPPP +PPPPP+ M PPP PPPPPS G+ PPPPP
Sbjct: 319 TAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPP 378
Query: 604 PPPAPAPAPVP 614
PPP P P P P
Sbjct: 379 PPPPPGPPPPP 389
Score = 71.2 bits (173), Expect = 3e-12
Identities = 50/128 (39%), Positives = 55/128 (42%), Gaps = 29/128 (22%)
Query: 544 GGLPAPPDDFLPPPPPPPP--LDDPELPPPPPDFMEPPPD-----FVPPPPPSYAGIAGS 596
GG+ A ++ PPPPP P PPPPP PPP PPPPPS A A
Sbjct: 263 GGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAP 322
Query: 597 ELPPP-------PPPPP----APAPAPVPDSA-----RPPPA------VAKRPPVPPKRQ 634
PPP PPPPP P P +P SA PPP+ VA PP PP
Sbjct: 323 PPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPP 382
Query: 635 ENPGHPGG 642
P P G
Sbjct: 383 PGPPPPPG 390
Score = 42.4 bits (98), Expect = 0.001
Identities = 28/78 (35%), Positives = 30/78 (38%), Gaps = 25/78 (32%)
Query: 495 PALGNHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFL 554
P + P P P + S PPPPP G G APP
Sbjct: 337 PPPNRMYPPPPPALPSSAPSGPPPPPP------------------SVLGVGPVAPP---- 374
Query: 555 PPPPPPPPLDDPELPPPP 572
PPPPPPPP P PPPP
Sbjct: 375 PPPPPPPP---PGPPPPP 389
Score = 32.0 bits (71), Expect = 1.9
Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 5/60 (8%)
Query: 120 GISQYEDDLPPPPADPVLDLPLPPPPPEPLSQEEEEAQAKADKIKLALEKLKE-AKVKKL 178
G+ PPPP P P PPPPP S + + A L++++E A++KK+
Sbjct: 367 GVGPVAPPPPPPPPPP----PGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKV 422
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 94.4 bits (233), Expect = 3e-19
Identities = 79/243 (32%), Positives = 100/243 (41%), Gaps = 62/243 (25%)
Query: 451 PAQPSTGPKTGTTQPNGQIPQATHSVSAVLQEAQRHAETSKDKK---------------- 494
P PS G QP Q P HS+S Q + H+ +S K
Sbjct: 811 PPPPSLLWSAGQGQPGSQPP---HSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESS 867
Query: 495 ---PALGNHHDPAVP----RAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGT------ 541
P LG P P P P +++P PPP++ ++ P PL G
Sbjct: 868 SSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQ-GTEMLPPPPPPLPGAGIPPPPPL 926
Query: 542 -GGGGLPAPP--DDFLPPPPP--------PPPLDDPELPPPPP---DFMEPPPDF----V 583
G G LP PP +PPPPP PPPL +P PPP + PPP +
Sbjct: 927 PGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGI 986
Query: 584 PPPPPSYAGIAGSELPPPPPPPPA--PAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPG 641
PPPPP + G+ +PPPPP P A P P P+P + PPP PP+P P
Sbjct: 987 PPPPP----LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-----PPLPGAGIPPPPPLP 1037
Query: 642 GAG 644
GAG
Sbjct: 1038 GAG 1040
Score = 91.7 bits (226), Expect = 2e-18
Identities = 56/147 (38%), Positives = 72/147 (48%), Gaps = 32/147 (21%)
Query: 505 VPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPD---DFLPPPPP-- 559
+P P P + +PPPPP+ +G P P G G+P PP +PPPPP
Sbjct: 1019 IPPPPPLPGAGIPPPPPL----PGAGIPPPP----PLPGAGIPPPPPLPGAGIPPPPPLP 1070
Query: 560 ------PPPLDDPELPPPPP---DFMEPPPDF----VPPPPPSYAGIAGSELPPPPPPPP 606
PPPL +PPPPP + PPP +PPPPP + G+ +PPPPP P
Sbjct: 1071 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP----LPGAGIPPPPPLPG 1126
Query: 607 A--PAPAPVPDSARPPPAVAKRPPVPP 631
A P P P+P + PPP R +PP
Sbjct: 1127 AGIPPPPPLPGAGIPPPPPLPRVGIPP 1153
Score = 89.7 bits (221), Expect = 8e-18
Identities = 58/150 (38%), Positives = 73/150 (48%), Gaps = 35/150 (23%)
Query: 505 VPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPD---DFLPPPPP-- 559
+P P P + +PPPPP+ +G P P G G+P PP +PPPPP
Sbjct: 964 IPLPPPLPGAGIPPPPPL----PGAGIPPPP----PLPGAGIPPPPPLPGAGIPPPPPLP 1015
Query: 560 ------PPPLDDPELPPPPP---DFMEPPPDF----VPPPPPSYAGIAGSELPPPPPPPP 606
PPPL +PPPPP + PPP +PPPPP + G+ +PPPPP P
Sbjct: 1016 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP----LPGAGIPPPPPLPG 1071
Query: 607 A--PAPAPVPDSARPPPAV---AKRPPVPP 631
A P P P+P + PPP A PP PP
Sbjct: 1072 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1101
Score = 89.4 bits (220), Expect = 1e-17
Identities = 57/149 (38%), Positives = 73/149 (48%), Gaps = 26/149 (17%)
Query: 505 VPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLD 564
+P P P +++PPPPP+ +G P P G G+P PP PPPPPL
Sbjct: 942 IPPPPPLPGAAIPPPPPL----PGAGIPLPP----PLPGAGIPPPPPLPGAGIPPPPPLP 993
Query: 565 DPELPPPPP---DFMEPPPDF----VPPPPPSYAGIAGSELPPPPPPPPA--PAPAPVPD 615
+PPPPP + PPP +PPPPP + G+ +PPPPP P A P P P+P
Sbjct: 994 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP----LPGAGIPPPPPLPGAGIPPPPPLPG 1049
Query: 616 SARPPPAVAKRPPVPPKRQENPGHPGGAG 644
+ PPP PP+P P GAG
Sbjct: 1050 AGIPPP-----PPLPGAGIPPPPPLPGAG 1073
Score = 89.0 bits (219), Expect = 1e-17
Identities = 60/162 (37%), Positives = 73/162 (45%), Gaps = 36/162 (22%)
Query: 505 VPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTG------GGGLPAPPD---DFLP 555
+P P P + +PPPPP+ P PL G G G+P PP +P
Sbjct: 1085 IPPPPPLPGAGIPPPPPL---PGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1141
Query: 556 PPPP--------PPPLDDPELPPPPP---DFMEPPPDF----VPPPPPSYAGIAGSELPP 600
PPPP PPPL +PPPPP + PPP +PPPPP + G +PP
Sbjct: 1142 PPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP----LPGVGIPP 1197
Query: 601 PPPPPPA--PAPAPVPDSARPPPAVAKRPPVPPKRQENPGHP 640
PPP P A P P P+P PP A PP+PP P P
Sbjct: 1198 PPPLPGAGIPPPPPLPGMGIPP---APAPPLPPPGTGIPPPP 1236
Score = 87.8 bits (216), Expect = 3e-17
Identities = 57/150 (38%), Positives = 72/150 (48%), Gaps = 35/150 (23%)
Query: 505 VPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPD---DFLPPPPP-- 559
+P P P + +PPPPP+ +G P P G G+P PP +PPPPP
Sbjct: 1041 IPPPPPLPGAGIPPPPPL----PGAGIPPPP----PLPGAGIPPPPPLPGAGIPPPPPLP 1092
Query: 560 ------PPPLDDPELPPPPP---DFMEPPPDF----VPPPPPSYAGIAGSELPPPPPPPP 606
PPPL +PPPPP + PPP +PPPPP + G+ +PPPPP P
Sbjct: 1093 GAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP----LPGAGIPPPPPLPR 1148
Query: 607 A--PAPAPVPDSARPPPAV---AKRPPVPP 631
P P P+P + PPP A PP PP
Sbjct: 1149 VGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1178
Score = 87.4 bits (215), Expect = 4e-17
Identities = 61/171 (35%), Positives = 77/171 (45%), Gaps = 48/171 (28%)
Query: 505 VPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPD---DFLPPPPP-- 559
+P P P + +PPPPP+ +G P P G G+P PP +PPPPP
Sbjct: 986 IPPPPPLPGAGIPPPPPL----PGAGIPPPP----PLPGAGIPPPPPLPGAGIPPPPPLP 1037
Query: 560 ------PPPLDDPELPPPPP---DFMEPPPDF----VPPPPPSYAGIAGSELPPPPP--- 603
PPPL +PPPPP + PPP +PPPPP + G+ +PPPPP
Sbjct: 1038 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP----LPGAGIPPPPPLPG 1093
Query: 604 ---PPPAPAPA-------PVPDSARPPPAVAKRPPVPPKRQENPGHPGGAG 644
PPP P P P+P + PPP PP+P P GAG
Sbjct: 1094 AGIPPPPPLPGVGIPPPPPLPGAGIPPP-----PPLPGAGIPPPPPLPGAG 1139
Score = 86.3 bits (212), Expect = 8e-17
Identities = 61/171 (35%), Positives = 76/171 (44%), Gaps = 48/171 (28%)
Query: 505 VPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPD---DFLPPPPP-- 559
+P P P + +PPPPP+ +G P P G G+P PP +PPPPP
Sbjct: 975 IPPPPPLPGAGIPPPPPL----PGAGIPPPP----PLPGAGIPPPPPLPGAGIPPPPPLP 1026
Query: 560 ------PPPLDDPELPPPPP---DFMEPPPDF----VPPPPPSYAGIAGSELPPPPP--- 603
PPPL +PPPPP + PPP +PPPPP + G+ +PPPPP
Sbjct: 1027 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP----LPGAGIPPPPPLPG 1082
Query: 604 ---PPPAPAPA-------PVPDSARPPPAVAKRPPVPPKRQENPGHPGGAG 644
PPP P P P+P PPP PP+P P GAG
Sbjct: 1083 AGIPPPPPLPGAGIPPPPPLPGVGIPPP-----PPLPGAGIPPPPPLPGAG 1128
Score = 86.3 bits (212), Expect = 8e-17
Identities = 58/154 (37%), Positives = 74/154 (48%), Gaps = 38/154 (24%)
Query: 505 VPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPD----DFLPPPP-- 558
+P P P + +PPPPP+ +G P P G G+P PP PPPP
Sbjct: 1107 IPPPPPLPGAGIPPPPPL----PGAGIPPPP----PLPGAGIPPPPPLPRVGIPPPPPLP 1158
Query: 559 -----PPPPLDDPELPPPPP---DFMEPPPDF----VPPPPPSYAGIAGSELPPPPP--- 603
PPPPL +PPPPP + PPP +PPPPP + G+ +PPPPP
Sbjct: 1159 GAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP----LPGAGIPPPPPLPG 1214
Query: 604 --PPPAPA-PAPVPDSARPPPAV--AKRPPVPPK 632
PPAPA P P P + PPP + PP+ P+
Sbjct: 1215 MGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQ 1248
Score = 81.6 bits (200), Expect = 2e-15
Identities = 60/171 (35%), Positives = 74/171 (43%), Gaps = 48/171 (28%)
Query: 505 VPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPD---DFLPPPPP-- 559
+P P P + +PPPPP+ +G P P G G+P PP +PPPPP
Sbjct: 1052 IPPPPPLPGAGIPPPPPL----PGAGIPPPP----PLPGAGIPPPPPLPGAGIPPPPPLP 1103
Query: 560 ------PPPLDDPELPPPPP---DFMEPPPDF----VPPPPPSYAGIAGSELPPPPP--- 603
PPPL +PPPPP + PPP +PPPPP + +PPPPP
Sbjct: 1104 GVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP----LPRVGIPPPPPLPG 1159
Query: 604 ---PPPAPAPA-------PVPDSARPPPAVAKRPPVPPKRQENPGHPGGAG 644
PPP P P P+P PPP PP+P P GAG
Sbjct: 1160 AGIPPPPPLPGAGIPPPPPLPGVGIPPP-----PPLPGVGIPPPPPLPGAG 1205
Score = 74.3 bits (181), Expect = 3e-13
Identities = 55/149 (36%), Positives = 63/149 (42%), Gaps = 32/149 (21%)
Query: 505 VPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTG------GGGLPAPPD----DFL 554
+P P P + +PPPPP+ R P PL G G G+P PP
Sbjct: 1129 IPPPPPLPGAGIPPPPPLPR---VGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIP 1185
Query: 555 PPPP-------PPPPLDDPELPPPPP-DFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPP 606
PPPP PPPPL +PPPPP M PP PP PP GI PPPP P
Sbjct: 1186 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGI------PPPPLLP 1239
Query: 607 APAPAPVPD---SARPPPAVA--KRPPVP 630
P +P S P P V PP+P
Sbjct: 1240 VSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
Score = 68.2 bits (165), Expect = 2e-11
Identities = 60/205 (29%), Positives = 75/205 (36%), Gaps = 79/205 (38%)
Query: 510 HAPKSSL--PPPPPVRRSSDTSGSPAT----------------PLKAKGTGGGGLPAPPD 551
H P S+ PPPPP S G P + + + +P+PP
Sbjct: 801 HQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPP 860
Query: 552 -------------DFLPPPPP-----------------PPPLDDPE-LPPPPPDF----M 576
+PPPPP PPPL E LPPPPP +
Sbjct: 861 LPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGI 920
Query: 577 EPPPDF---------------VPPPPPSYAGIAGSELPPPPPPPPA--PAPAPVPDSARP 619
PPP +PPPPP + G+ +PPPPP P A P P P+P + P
Sbjct: 921 PPPPPLPGAGILPLPPLPGAGIPPPPP----LPGAAIPPPPPLPGAGIPLPPPLPGAGIP 976
Query: 620 PPAVAKRPPVPPKRQENPGHPGGAG 644
PP PP+P P GAG
Sbjct: 977 PP-----PPLPGAGIPPPPPLPGAG 996
Score = 41.6 bits (96), Expect = 0.002
Identities = 36/130 (27%), Positives = 42/130 (32%), Gaps = 41/130 (31%)
Query: 543 GGGLPAPPDDFLPPPPPPPP----------------LDDPELPPPPPDFMEPPPDF-VPP 585
GG L PP D LP PP PP + P D +P PP
Sbjct: 752 GGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPP 811
Query: 586 PPPSYAGIAGSELPPPPPPP------------------------PAPAPAPVPDSARPPP 621
PPPS AG P PP P+P P P +S+ P
Sbjct: 812 PPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMP 871
Query: 622 AVAKRPPVPP 631
+ PP PP
Sbjct: 872 GLGMVPPPPP 881
Score = 32.0 bits (71), Expect = 1.9
Identities = 24/66 (36%), Positives = 26/66 (39%), Gaps = 8/66 (12%)
Query: 495 PALGNHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPP-DDF 553
P L P P P P + PPPP+ SG P P G LP P F
Sbjct: 1210 PPLPGMGIPPAPAPPLPPPGTGIPPPPL---LPVSGPPLLP----QVGSSTLPTPQVCGF 1262
Query: 554 LPPPPP 559
LPPP P
Sbjct: 1263 LPPPLP 1268
Score = 30.4 bits (67), Expect = 5.5
Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 7/29 (24%)
Query: 128 LPPPPADPVLDLPLPP-------PPPEPL 149
+PPPP P +PLPP PPP PL
Sbjct: 953 IPPPPPLPGAGIPLPPPLPGAGIPPPPPL 981
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 89.7 bits (221), Expect = 8e-18
Identities = 66/210 (31%), Positives = 83/210 (39%), Gaps = 54/210 (25%)
Query: 476 VSAVLQEAQRHAETSKDKKPALGNHHDPAVPRAPHAP-KSSLPPPPPVRRSSDTSGSPAT 534
VS + E + + +D K + + A+ P P ++ +PP PP+ S T P
Sbjct: 532 VSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPP- 590
Query: 535 PLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELP-----PPPPDF-----MEPPPDF-- 582
PAP D PPPPPPPP P LP PP + PPP
Sbjct: 591 ------------PAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSG 638
Query: 583 ---VPPPPPSYAGIA---------GSELPP----------PPPPPPAPAPAPVPDSARPP 620
+PPPPP G+ G+ +PP PPPPPP P A +P P
Sbjct: 639 DATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPL 698
Query: 621 PAVAKRPPVPPKRQENPG------HPGGAG 644
P A PP PP PG PGG G
Sbjct: 699 PGEAGMPPPPPPLPGGPGIPPPPPFPGGPG 728
Score = 78.6 bits (192), Expect = 2e-14
Identities = 47/122 (38%), Positives = 57/122 (46%), Gaps = 18/122 (14%)
Query: 506 PRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLP-----PPPPP 560
P P + +++PPPPP+ + P GG +P PP LP PPPPP
Sbjct: 632 PPPPLSGDATIPPPPPLPEGVGIPSPSSLP------GGTAIPPPPP--LPGSARIPPPPP 683
Query: 561 PPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPA-PAPVPDSARP 619
P +PPPPP P +PPPPP G G +PPPPP P P P P P P
Sbjct: 684 PLPGSAGIPPPPPPL--PGEAGMPPPPPPLPG--GPGIPPPPPFPGGPGIPPPPPGMGMP 739
Query: 620 PP 621
PP
Sbjct: 740 PP 741
Score = 38.1 bits (87), Expect = 0.026
Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 4/113 (3%)
Query: 40 RAEFNYSVGFKDLNESLNAL--EDQDLDALMADLVADISEAEQRTIQAQKESLQNQHHSA 97
+ E ++ +DL +AL E Q + DL A++S+ + KE + A
Sbjct: 495 KMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMA 554
Query: 98 SLQASIFSGAASLGYGTNVAATGISQYEDD--LPPPPADPVLDLPLPPPPPEP 148
SL A+ + S+ V + +PPPPA P PPPPP P
Sbjct: 555 SLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPP 607
Score = 34.3 bits (77), Expect = 0.38
Identities = 26/98 (26%), Positives = 42/98 (42%), Gaps = 13/98 (13%)
Query: 58 ALEDQDLDALMADLVADISEAEQRTIQAQKESLQNQHHSASLQASIFSGAASL------G 111
A E QDL+A ++ L ++++ + A+KE + ++ S+ S A G
Sbjct: 522 ATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPG 581
Query: 112 YGTNVAATGISQYEDDLPPPPADPVLDLPLPPPPPEPL 149
+ + + PPPP P PPPPP PL
Sbjct: 582 DSGTIIPPPPAPGDSTTPPPP-------PPPPPPPPPL 612
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 89.7 bits (221), Expect = 8e-18
Identities = 66/210 (31%), Positives = 83/210 (39%), Gaps = 54/210 (25%)
Query: 476 VSAVLQEAQRHAETSKDKKPALGNHHDPAVPRAPHAP-KSSLPPPPPVRRSSDTSGSPAT 534
VS + E + + +D K + + A+ P P ++ +PP PP+ S T P
Sbjct: 541 VSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPP- 599
Query: 535 PLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELP-----PPPPDF-----MEPPPDF-- 582
PAP D PPPPPPPP P LP PP + PPP
Sbjct: 600 ------------PAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSG 647
Query: 583 ---VPPPPPSYAGIA---------GSELPP----------PPPPPPAPAPAPVPDSARPP 620
+PPPPP G+ G+ +PP PPPPPP P A +P P
Sbjct: 648 DATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPL 707
Query: 621 PAVAKRPPVPPKRQENPG------HPGGAG 644
P A PP PP PG PGG G
Sbjct: 708 PGEAGMPPPPPPLPGGPGIPPPPPFPGGPG 737
Score = 78.6 bits (192), Expect = 2e-14
Identities = 47/122 (38%), Positives = 57/122 (46%), Gaps = 18/122 (14%)
Query: 506 PRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLP-----PPPPP 560
P P + +++PPPPP+ + P GG +P PP LP PPPPP
Sbjct: 641 PPPPLSGDATIPPPPPLPEGVGIPSPSSLP------GGTAIPPPPP--LPGSARIPPPPP 692
Query: 561 PPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPA-PAPVPDSARP 619
P +PPPPP P +PPPPP G G +PPPPP P P P P P P
Sbjct: 693 PLPGSAGIPPPPPPL--PGEAGMPPPPPPLPG--GPGIPPPPPFPGGPGIPPPPPGMGMP 748
Query: 620 PP 621
PP
Sbjct: 749 PP 750
Score = 38.1 bits (87), Expect = 0.026
Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 4/113 (3%)
Query: 40 RAEFNYSVGFKDLNESLNAL--EDQDLDALMADLVADISEAEQRTIQAQKESLQNQHHSA 97
+ E ++ +DL +AL E Q + DL A++S+ + KE + A
Sbjct: 504 KMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMA 563
Query: 98 SLQASIFSGAASLGYGTNVAATGISQYEDD--LPPPPADPVLDLPLPPPPPEP 148
SL A+ + S+ V + +PPPPA P PPPPP P
Sbjct: 564 SLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPP 616
Score = 34.3 bits (77), Expect = 0.38
Identities = 26/98 (26%), Positives = 42/98 (42%), Gaps = 13/98 (13%)
Query: 58 ALEDQDLDALMADLVADISEAEQRTIQAQKESLQNQHHSASLQASIFSGAASL------G 111
A E QDL+A ++ L ++++ + A+KE + ++ S+ S A G
Sbjct: 531 ATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPG 590
Query: 112 YGTNVAATGISQYEDDLPPPPADPVLDLPLPPPPPEPL 149
+ + + PPPP P PPPPP PL
Sbjct: 591 DSGTIIPPPPAPGDSTTPPPP-------PPPPPPPPPL 621
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 86.7 bits (213), Expect = 6e-17
Identities = 60/185 (32%), Positives = 78/185 (42%), Gaps = 33/185 (17%)
Query: 454 PSTGPKTGTTQPNGQIPQATHSVSAVLQEAQRHAETSKDKKPALGNHHDPAVPRAPHAPK 513
P P+ G P G + Q ++ + +E + + + G + + P AP
Sbjct: 592 PRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPI 651
Query: 514 SSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPP 573
+S P P+ + + A + A LP PP PP PPPPP PPP P
Sbjct: 652 TSADCPKPMVVTPGAAAVAAPSVLAPT-----LPLPPPPGFPPLPPPPPP-----PPPQP 701
Query: 574 DFMEPPPDFVPPPPPSYAGIAGSELPPPP-------PPPPAPAPAPVPDSARPPPAVAKR 626
F PPP +PPPPP PPPP PPPP PAP VP PPP +
Sbjct: 702 GFPMPPP--LPPPPP----------PPPPAHPAVTVPPPPLPAPPGVP----PPPILPPL 745
Query: 627 PPVPP 631
PP PP
Sbjct: 746 PPFPP 750
Score = 57.8 bits (138), Expect = 3e-08
Identities = 36/95 (37%), Positives = 40/95 (42%), Gaps = 23/95 (24%)
Query: 503 PAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPP 562
P +P P LPPPPP P P G P PP LPPPPPPPP
Sbjct: 677 PTLPLPPPPGFPPLPPPPPP--------PPPQP---------GFPMPPP--LPPPPPPPP 717
Query: 563 LDDPELPPPPPDFMEPP----PDFVPPPPPSYAGI 593
P + PPP PP P +PP PP G+
Sbjct: 718 PAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGL 752
Score = 47.0 bits (110), Expect = 6e-05
Identities = 63/215 (29%), Positives = 75/215 (34%), Gaps = 39/215 (18%)
Query: 443 LGTVNAAAPAQPSTGPKTGT-----TQPNGQIPQATHSVS---AVLQEAQRHAETSKDKK 494
L T N+ P T P+ GT + + + P ++ S AV +A+RH D
Sbjct: 263 LDTPNSYGQGTPLT-PRLGTPFSQDSSYSSRQPTPSYLFSQDPAVTFKARRHESKFTDAY 321
Query: 495 PALGNHH----DPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPP 550
HH PAV A + R SSD P A G GG
Sbjct: 322 NRRHEHHYVHNSPAVTAVAGATAA-------FRGSSDL------PFGAVGGTGGSSG--- 365
Query: 551 DDFLPPPPPPPPLDDPELP-PPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPA 609
PP P D PPP P P F P +A PPPP P A A
Sbjct: 366 -----PPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVA--HFPPPPEEPTATA 418
Query: 610 PAPVPDSA--RPPPAVAKRPPVPPKRQENPGHPGG 642
DS R PA PP P +E PG P G
Sbjct: 419 AFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPG 453
Score = 45.1 bits (105), Expect = 2e-04
Identities = 46/149 (30%), Positives = 54/149 (36%), Gaps = 33/149 (22%)
Query: 508 APHAPKSSLPPPP---PVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPP---- 560
AP S L PP V +D+ P P GL L P PP
Sbjct: 1199 APEERPSMLDEPPLPVGVEEPADSREPPEEP---------GLSQEGAMLLSPEPPAKEVE 1249
Query: 561 --PPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSAR 618
PPL PE P +EP P + P P L PP PPP P P P
Sbjct: 1250 ARPPLS-PERAPEHDLEVEPEPPMMLPLP----------LQPPLPPPRPPRPPSPP--PE 1296
Query: 619 PPPAVAKRPPVPPK--RQENPGHPGGAGG 645
P A P VPP+ +++P H G G
Sbjct: 1297 PETTDASHPSVPPEPLAEDHPPHTPGLCG 1325
Score = 43.9 bits (102), Expect = 5e-04
Identities = 43/159 (27%), Positives = 63/159 (39%), Gaps = 36/159 (22%)
Query: 4 SSEDIDQMFSTLLGEMDLLTQ-SLGVDTLPPPDPNPPRAEFNYSVGFKDLNESLNALEDQ 62
SS ++ + T L + D + LG+ PPP+P PP L Q
Sbjct: 565 SSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPA---------------GLLSQ 609
Query: 63 DLDALMADLVADISEAEQRTIQAQKESLQNQHHSASLQAS-------------IFSGAAS 109
+ + DLV D + ++ + Q+ S ++ S S + GAA+
Sbjct: 610 TAEVAL-DLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAA 668
Query: 110 LGYGTNVAATGISQYEDDLPPPPADPVLDLPLPPPPPEP 148
VAA + LPPPP P L P PPPPP+P
Sbjct: 669 ------VAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQP 701
Score = 43.1 bits (100), Expect = 8e-04
Identities = 31/88 (35%), Positives = 40/88 (45%), Gaps = 19/88 (21%)
Query: 545 GLPAPPDDFLP---PPPPPPPLDDPELPPPPPDFMEPPPDFVPPPP-------PSYAGIA 594
G+PAPP P PPPPPPP++ +LP D + P + +PP P Y +A
Sbjct: 1535 GIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELD-NQWPSEAIPPGPRGRDEVTEEYMELA 1593
Query: 595 GSELPPPPPP--------PPAPAPAPVP 614
S P PP PPA +P P
Sbjct: 1594 KSRGPWRRPPKKRHEDLVPPAGSPELSP 1621
Score = 41.6 bits (96), Expect = 0.002
Identities = 52/190 (27%), Positives = 62/190 (32%), Gaps = 41/190 (21%)
Query: 490 SKDKKPALGNHHDPAVPRAPHAPKSSLPPPPP-----VRRSSDTSGSPATPLKAKGTGGG 544
S +P + P+VP P A PP P + +S T PATP GG
Sbjct: 1292 SPPPEPETTDASHPSVPPEPLAEDH--PPHTPGLCGSLAKSQSTETVPATPGGEPPLSGG 1349
Query: 545 --GL----PAPPDDFLPPPPPPPPLDDPELPPPP-------PDFMEPPPDFVPPPPPSYA 591
GL P P P P P L LP P P F EP + P P
Sbjct: 1350 SSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPT 1409
Query: 592 G--------IAGSELPPPPPPPPAPAPAPVP-------------DSARPPPAVAKRPPVP 630
G +A L P P P P P+P + PP A P
Sbjct: 1410 GRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCP 1469
Query: 631 PKRQENPGHP 640
P + PG P
Sbjct: 1470 PPMKRKPGRP 1479
Score = 40.0 bits (92), Expect = 0.007
Identities = 43/156 (27%), Positives = 53/156 (33%), Gaps = 29/156 (18%)
Query: 506 PRAPHAPKSSLPPPPPVRRSS-DTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLD 564
P P + PP P R D P P+ LP P L PP PPP
Sbjct: 1241 PEPPAKEVEARPPLSPERAPEHDLEVEPEPPMM--------LPLP----LQPPLPPPRPP 1288
Query: 565 DPELPPPPPDFMEPPPDFVPPP------PPSYAGIAGS-------ELPPPPP---PPPAP 608
P PPP P+ + VPP PP G+ GS E P P PP +
Sbjct: 1289 RPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSG 1348
Query: 609 APAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGAG 644
+ + S+ P P P + G P G
Sbjct: 1349 GSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPG 1384
Score = 40.0 bits (92), Expect = 0.007
Identities = 46/159 (28%), Positives = 56/159 (35%), Gaps = 44/159 (27%)
Query: 503 PAVPRAPHAPKSSLPP---------PPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDD- 552
PAV RA + LPP PPP++R G P + + G L PP
Sbjct: 1444 PAVLRAQARAPTPLPPLLPAPLASCPPPMKRKP---GRPRRSPPSMLSLDGPLVRPPAGA 1500
Query: 553 -------FLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPP 605
LP P P P P ++ +P PPP P PP PP
Sbjct: 1501 ALGRELLLLPGQPQTPVF--PSTHDPRTVTLDFRNAGIPAPPP----------PLPPQPP 1548
Query: 606 PAPAPAPVP---------DSARPPPAVAKRPPVPPKRQE 635
P P P PV D+ P A+ PP P R E
Sbjct: 1549 PPPPPPPVEPTKLPFKELDNQWPSEAI---PPGPRGRDE 1584
Score = 36.6 bits (83), Expect = 0.077
Identities = 47/198 (23%), Positives = 60/198 (30%), Gaps = 59/198 (29%)
Query: 519 PPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLP---------------PPPPPPPL 563
P P R + SG A+P+ + GLP P LP P P PP L
Sbjct: 1406 PLPTGRRDERSGPLASPVLLET----GLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLL 1461
Query: 564 DDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPP--------------------- 602
P PPP M+ P PPS + G + PP
Sbjct: 1462 PAPLASCPPP--MKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFP 1519
Query: 603 -----------------PPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGAGG 645
P PP P P P PPP + P + P G
Sbjct: 1520 STHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGP 1579
Query: 646 GEQDFMSDLMKALQKKRG 663
+D +++ L K RG
Sbjct: 1580 RGRDEVTEEYMELAKSRG 1597
Score = 35.8 bits (81), Expect = 0.13
Identities = 31/104 (29%), Positives = 37/104 (35%), Gaps = 27/104 (25%)
Query: 512 PKSSLPPPPP---------VRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFL-------P 555
P + PPPP R S + +PA P P PP + L P
Sbjct: 403 PVAHFPPPPEEPTATAAFGARDSGEFRRAPAPP-----------PLPPAEPLAKEKPGTP 451
Query: 556 PPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELP 599
P PPPP + EL P P P P P + AG E P
Sbjct: 452 PGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKP 495
Score = 35.0 bits (79), Expect = 0.22
Identities = 41/170 (24%), Positives = 47/170 (27%), Gaps = 31/170 (18%)
Query: 503 PAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPP 562
PA P A P + PPPP S + G P + G P P P
Sbjct: 439 PAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDS 498
Query: 563 LD----------------------DPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPP 600
LD D EL P P G P
Sbjct: 499 LDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPT 558
Query: 601 PPPPPPAP------APAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGAG 644
PP P+ +P P+PDS P PP PG P AG
Sbjct: 559 PPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPP---PEPGPPDPAG 605
Score = 30.0 bits (66), Expect = 7.2
Identities = 11/20 (55%), Positives = 13/20 (65%)
Query: 129 PPPPADPVLDLPLPPPPPEP 148
PPPPA P + +P PP P P
Sbjct: 715 PPPPAHPAVTVPPPPLPAPP 734
Score = 30.0 bits (66), Expect = 7.2
Identities = 12/20 (60%), Positives = 12/20 (60%)
Query: 129 PPPPADPVLDLPLPPPPPEP 148
PPPP P P PPPP EP
Sbjct: 1539 PPPPLPPQPPPPPPPPPVEP 1558
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 84.0 bits (206), Expect = 4e-16
Identities = 78/245 (31%), Positives = 94/245 (38%), Gaps = 50/245 (20%)
Query: 447 NAAAPAQPSTGPKTGTTQPN----GQIPQATHSVSAVLQEAQRHAETSKDKKPALGNHHD 502
N AA P PK TT P P ++A L EA+ P +
Sbjct: 345 NKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKV-QIPP 403
Query: 503 PAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATP--------------LKAKGTGGGGLP- 547
PA P H P PPP SS +G T +K +G G LP
Sbjct: 404 PAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPP 463
Query: 548 --APPDDF------LPPPPPPPPLDDPE-------LPPPPPDFMEPPPDF---VPPPPPS 589
PP PP PPPPP+ P +PPP P + PPP + PPPPP
Sbjct: 464 AYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPP- 522
Query: 590 YAGIAGSELPPPPPPPPAPAPA-PVPDSARPPPAV--AKRPPVPPKRQENPGHPGGAGGG 646
LPP PP P P +P ++ PPPAV +PPVPP PG P G G
Sbjct: 523 -------RLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPP-PGMPPVGGLG 574
Query: 647 EQDFM 651
+M
Sbjct: 575 RAAWM 579
Score = 59.7 bits (143), Expect = 8e-09
Identities = 50/176 (28%), Positives = 67/176 (38%), Gaps = 39/176 (22%)
Query: 464 QPNGQIPQATHSVSAVLQEAQRHAETSKDKKPALGNHHDPAVPRAPHAPKSSLPPPPPVR 523
QP Q+PQ S + S+ +P+ DP P P P P
Sbjct: 280 QPTPQVPQVQQS------------QPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSP-- 325
Query: 524 RSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFV 583
P++P + K + +P ++ PPPP + E PP PPPD
Sbjct: 326 -------QPSSPRQVKRAV---VVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRK 375
Query: 584 PP--------PPPSYAGIAGSELPPPPPPPPAPAPAPVPDSARPPPAVAKRPPVPP 631
PP PP + ++LP PPPA PAPV PP + RPP PP
Sbjct: 376 PPLAAALGEAEPP--GPVDATDLPKVQIPPPA-HPAPV----HQPPPLPHRPPPPP 424
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 83.2 bits (204), Expect = 7e-16
Identities = 66/201 (32%), Positives = 79/201 (39%), Gaps = 49/201 (24%)
Query: 502 DPAVPRAPHAPKSSLPPPP-----PV-----------RRSSDTSGSPATPLKAKGTGGGG 545
D A +P + +LPPPP PV +RSS S S P G+ G
Sbjct: 253 DSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGP 312
Query: 546 LPA-----------PPDDFLPPPPPPPPLDDPELPPPP--------PDFMEPPPDFVPP- 585
P PP +PPPPPP P PPPP PDF PPP PP
Sbjct: 313 KPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPA 372
Query: 586 ------PPPSYAGIAGSELPPPPPPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGH 639
PPP + G PPPPPPPP P P P PP A P P +
Sbjct: 373 ADYPTLPPPPLSQPTGGAPPPPPPPPP-PGPPP------PPFTGADGQPAIPPPLSDTTK 425
Query: 640 PGGAGGGEQDFMSDLMKALQK 660
P + D SDL+ A+++
Sbjct: 426 PKSSLPAVSDARSDLLSAIRQ 446
Score = 81.6 bits (200), Expect = 2e-15
Identities = 56/136 (41%), Positives = 59/136 (43%), Gaps = 29/136 (21%)
Query: 495 PALGNHHDP----AVPRAPHAPKSSL----PPPPPVRRSSDTSGSPATPLKAKGTGGGGL 546
P LG+ P A P AP P + PPPPPV GSP TP
Sbjct: 304 PPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPV-----GFGSPGTP---PPPSPPSF 355
Query: 547 PAPPDDFLPPPPPPPPLDD-PELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPP 605
P PD PPPPPPPP D P LPPPP + P PPPPP PPPP PP
Sbjct: 356 PPHPDFAAPPPPPPPPAADYPTLPPPP---LSQPTGGAPPPPPP---------PPPPGPP 403
Query: 606 PAPAPAPVPDSARPPP 621
P P A PPP
Sbjct: 404 PPPFTGADGQPAIPPP 419
Score = 61.2 bits (147), Expect = 3e-09
Identities = 55/188 (29%), Positives = 72/188 (38%), Gaps = 37/188 (19%)
Query: 479 VLQEAQRHAETSKDKKPALGNHHDPAVP-RAPHAPKSSLPPP-PPVRRSSDTSGSPATPL 536
+++E ++H + KD P GN + + R K + + TSG P T +
Sbjct: 171 IMKEKRKHRKEKKDN-PNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLV 229
Query: 537 KAKGTGGGGLPAPPDDFLPPPP------PPPPLDDPELPPPPPDFMEP------------ 578
G+ G + PPP P P + LPPPP +F P
Sbjct: 230 YQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGP 289
Query: 579 ------PPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSARPPPAVAKRPPVPPK 632
P PP PP GS PP P P AP PAP P PPP + PP PP
Sbjct: 290 KRSSVVSPSHPPPAPP-----LGS--PPGPKPGFAPPPAPPPP---PPPMIGIPPPPPPV 339
Query: 633 RQENPGHP 640
+PG P
Sbjct: 340 GFGSPGTP 347
Score = 57.0 bits (136), Expect = 5e-08
Identities = 33/85 (38%), Positives = 41/85 (48%), Gaps = 7/85 (8%)
Query: 498 GNHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPP 557
G P+ P P P + PPPPP ++D P PL ++ TGG P PP PP
Sbjct: 345 GTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPL-SQPTGGAPPPPPPPP--PPG 401
Query: 558 PPPPPL----DDPELPPPPPDFMEP 578
PPPPP P +PPP D +P
Sbjct: 402 PPPPPFTGADGQPAIPPPLSDTTKP 426
Score = 31.2 bits (69), Expect = 3.2
Identities = 10/17 (58%), Positives = 13/17 (76%)
Query: 129 PPPPADPVLDLPLPPPP 145
PPPP P++ +P PPPP
Sbjct: 322 PPPPPPPMIGIPPPPPP 338
Score = 30.8 bits (68), Expect = 4.2
Identities = 11/18 (61%), Positives = 11/18 (61%)
Query: 129 PPPPADPVLDLPLPPPPP 146
PPPP P D P PPPP
Sbjct: 365 PPPPPPPAADYPTLPPPP 382
Score = 30.4 bits (67), Expect = 5.5
Identities = 13/22 (59%), Positives = 14/22 (63%), Gaps = 1/22 (4%)
Query: 128 LPPPP-ADPVLDLPLPPPPPEP 148
LPPPP + P P PPPPP P
Sbjct: 378 LPPPPLSQPTGGAPPPPPPPPP 399
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 80.5 bits (197), Expect = 5e-15
Identities = 63/174 (36%), Positives = 70/174 (40%), Gaps = 20/174 (11%)
Query: 478 AVLQEAQ-RHAETSKDKKPALGNHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPL 536
A + EAQ AETSK + + R + LPPPPP R + P
Sbjct: 274 AGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVG 333
Query: 537 KAKGTGGGGLPAPPDDFLPPPP----PPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAG 592
KG G LP P PPPP PPPP PPPPP P +PPPPP G
Sbjct: 334 GNKGRSGP-LPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRSGP--LPPPPPGAGG 390
Query: 593 IAGSELPPPPPPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGAGGG 646
PP PPP P P P P S P PP+PP G G G G
Sbjct: 391 --------PPMPPPPPPPPPPPSSGNGPAP----PPLPPALVPAGGLAPGGGRG 432
Score = 30.8 bits (68), Expect = 4.2
Identities = 24/92 (26%), Positives = 35/92 (38%), Gaps = 7/92 (7%)
Query: 557 PPPPPPLDDPELPPPPPDFMEPPPD-FVPPPPPSYAGIAGSELPPPPPPP------PAPA 609
PPPP P ++ PP + P D PP P G+A ++ P PAP
Sbjct: 160 PPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPG 219
Query: 610 PAPVPDSARPPPAVAKRPPVPPKRQENPGHPG 641
P+P ++K P ++ H G
Sbjct: 220 PSPADKKRSGKKKISKADIGAPSGFKHVSHVG 251
Score = 30.4 bits (67), Expect = 5.5
Identities = 14/26 (53%), Positives = 15/26 (57%), Gaps = 3/26 (11%)
Query: 128 LPPPP---ADPVLDLPLPPPPPEPLS 150
LPPPP P + P PPPPP P S
Sbjct: 381 LPPPPPGAGGPPMPPPPPPPPPPPSS 406
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 79.0 bits (193), Expect = 1e-14
Identities = 61/183 (33%), Positives = 76/183 (41%), Gaps = 49/183 (26%)
Query: 462 TTQPNGQIPQATHSVS-AVLQEAQRHAETSKDKKPALG--NHHDPAVPRAPHAPKSSLPP 518
TT+ N +P+ + S + L H + +P G ++ A+P P +S+PP
Sbjct: 599 TTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALP----PPPASIPP 654
Query: 519 PPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEP 578
PPP LP+ P PP PP P LPPPPP P
Sbjct: 655 PPP------------------------LPSGLGSLSPAPPMPPVSAGPPLPPPPP----P 686
Query: 579 PPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPG 638
PP P PPPS AG PPPPPPPP P+P+S PP P PP P
Sbjct: 687 PP---PLPPPSSAG------PPPPPPPP-----PLPNSPAPPNPGGPPPAPPPPGLAPPP 732
Query: 639 HPG 641
PG
Sbjct: 733 PPG 735
Score = 61.2 bits (147), Expect = 3e-09
Identities = 36/82 (43%), Positives = 39/82 (47%), Gaps = 21/82 (25%)
Query: 576 MEPPPDFVPPPPP--SYAG-----------IAGSELPPPPPPPPAPAPAPVPDSARPPPA 622
+ PPP +PPPPP S G AG LPPPPPPPP P P P SA PPP
Sbjct: 645 LPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPP---PLPPPSSAGPPP- 700
Query: 623 VAKRPPVPPKRQENPGHPGGAG 644
PP PP +P P G
Sbjct: 701 ----PPPPPPLPNSPAPPNPGG 718
Score = 39.3 bits (90), Expect = 0.012
Identities = 21/53 (39%), Positives = 25/53 (47%), Gaps = 4/53 (7%)
Query: 598 LPPPP----PPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGAGGG 646
LPPPP PPPP P+ A P P V+ PP+PP P P + G
Sbjct: 645 LPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAG 697
Score = 30.0 bits (66), Expect = 7.2
Identities = 13/31 (41%), Positives = 15/31 (48%)
Query: 119 TGISQYEDDLPPPPADPVLDLPLPPPPPEPL 149
+G+ P PP LP PPPPP PL
Sbjct: 660 SGLGSLSPAPPMPPVSAGPPLPPPPPPPPPL 690
Score = 29.6 bits (65), Expect = 9.4
Identities = 14/26 (53%), Positives = 14/26 (53%), Gaps = 5/26 (19%)
Query: 129 PPPPADPVLDLPL-----PPPPPEPL 149
PPPP P L P PPPPP PL
Sbjct: 682 PPPPPPPPLPPPSSAGPPPPPPPPPL 707
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 79.0 bits (193), Expect = 1e-14
Identities = 55/149 (36%), Positives = 60/149 (40%), Gaps = 17/149 (11%)
Query: 503 PAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPP 562
PA P P P PPPP+ +G P P + LP PP LP PP PP
Sbjct: 218 PAPPSLPAGPPGVKRPPPPLM-----NGLPPRPPLPES-----LPPPPPGGLPLPPMPPT 267
Query: 563 LDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPA---PAP---VPDS 616
P PP PP P P PP P + +G P P PPAP PAP P S
Sbjct: 268 GPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTS 327
Query: 617 ARPPPAVAKRPPVPPKRQENPG-HPGGAG 644
PPA PP P PG HP G
Sbjct: 328 GVHPPAPGVHPPAPGVHPPAPGVHPPAPG 356
Score = 71.2 bits (173), Expect = 3e-12
Identities = 60/186 (32%), Positives = 69/186 (37%), Gaps = 27/186 (14%)
Query: 484 QRHAETSKDKKPALGNHHDPAVPRAPHAPKSSLPPPPPVRRS---SDTSGSPATPLKAKG 540
Q H + K P P V R P + LPP PP+ S G P P+ G
Sbjct: 209 QFHFKMEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTG 268
Query: 541 TGGGGLPAPPDDFLPPP-----PPPPPLDDPE--LPPPPPDFMEPPPDFVPPPP---PSY 590
G P PP LPPP PP P + P + PP P P P PP P P
Sbjct: 269 PAPSGPPGPPQ--LPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPT 326
Query: 591 AGI---AGSELPPPP---PP-----PPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPG- 638
+G+ A PP P PP PPAP P PPP+ P P P
Sbjct: 327 SGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAV 386
Query: 639 HPGGAG 644
HP G
Sbjct: 387 HPQAPG 392
Score = 53.5 bits (127), Expect = 6e-07
Identities = 60/206 (29%), Positives = 66/206 (32%), Gaps = 30/206 (14%)
Query: 451 PAQPSTGPKTGTTQPNGQIPQATHSVSAVLQEAQRHAETSKDKKPALGNHHD-PAV-PRA 508
P P TGP Q+P V H S PA G H P V P A
Sbjct: 262 PPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVV--HPPASGVHPPAPGVHPPAPGVHPPA 319
Query: 509 P--HAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPP-------- 558
P H P S + PP P P P G PAP + PPP
Sbjct: 320 PGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPG---VHPPPSAGVHPQA 376
Query: 559 ----PPPPLDDPELP---PPPPDFMEPPPDFVPPPPPSYAGIAGSELPPP---PPPPPAP 608
P P P+ P PP P P P PP + G PP P P
Sbjct: 377 PGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVH 436
Query: 609 APAPVPDSARPP---PAVAKRPPVPP 631
P P+P RPP PP PP
Sbjct: 437 PPTPMPPMLRPPLPSEGPGNIPPPPP 462
Score = 36.2 bits (82), Expect = 0.10
Identities = 30/95 (31%), Positives = 38/95 (40%), Gaps = 23/95 (24%)
Query: 503 PAV-PRAP--HAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPP-----DDFL 554
PAV P+AP H P + P P P+ P G P PP + +
Sbjct: 384 PAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAP--------GVHPQPPGVHPSNPGV 435
Query: 555 PPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPS 589
PP P PP+ P LP P +PPPPP+
Sbjct: 436 HPPTPMPPMLRPPLP-------SEGPGNIPPPPPT 463
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 78.6 bits (192), Expect = 2e-14
Identities = 49/126 (38%), Positives = 56/126 (44%), Gaps = 37/126 (29%)
Query: 498 GNHHDPAVPRAPHAPKSSLPPPPPVRRSSDT----SGSPATPLKAKGTGGGGLPAPPDDF 553
GN P + A P PPPPP+ SSDT P TP P PP
Sbjct: 511 GNSVGPTMGAASSGPLP--PPPPPLPPSSDTPETVQNGPVTP-----------PMPP--- 554
Query: 554 LPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPV 613
PPPPPPPP PPPPP PPPPP G A +P PP PP P+ P+
Sbjct: 555 -PPPPPPPP------PPPPP----------PPPPPPLPGPAAETVPAPPLAPPLPSAPPL 597
Query: 614 PDSARP 619
P ++ P
Sbjct: 598 PGTSSP 603
Score = 59.7 bits (143), Expect = 8e-09
Identities = 40/116 (34%), Positives = 44/116 (37%), Gaps = 26/116 (22%)
Query: 525 SSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVP 584
S +G+ P + G P PP PPPP PP D PE P V
Sbjct: 506 SEVVAGNSVGPTMGAASSG---PLPP----PPPPLPPSSDTPETVQNGP---------VT 549
Query: 585 PPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHP 640
PP P PPPPPPPP P P P P P A+ P PP P P
Sbjct: 550 PPMP----------PPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAP 595
Score = 39.7 bits (91), Expect = 0.009
Identities = 22/59 (37%), Positives = 25/59 (42%), Gaps = 9/59 (15%)
Query: 594 AGSELPPPPPPPPAPAPAPVPDS---------ARPPPAVAKRPPVPPKRQENPGHPGGA 643
A S P PPPPPP P + P++ PPP PP PP P PG A
Sbjct: 520 AASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPA 578
Score = 32.7 bits (73), Expect = 1.1
Identities = 13/21 (61%), Positives = 13/21 (61%)
Query: 129 PPPPADPVLDLPLPPPPPEPL 149
PPPP P P PPPPP PL
Sbjct: 554 PPPPPPPPPPPPPPPPPPPPL 574
Score = 32.0 bits (71), Expect = 1.9
Identities = 34/127 (26%), Positives = 49/127 (38%), Gaps = 31/127 (24%)
Query: 49 FKDLNESLNAL-----EDQDLDALMADLVADISEAE-QRTIQAQKESLQNQHHSASLQAS 102
+KD N ++ L E ++ + L I E E Q TI+ QK+ ++
Sbjct: 441 YKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGTIKIQKKG----DGDIAILPV 496
Query: 103 IFSGAASLGY----GTNVAATGISQYEDDLPPPP-----------------ADPVLDLPL 141
+ SG S+G G +V T + LPPPP P + P
Sbjct: 497 VASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPP 556
Query: 142 PPPPPEP 148
PPPPP P
Sbjct: 557 PPPPPPP 563
Score = 32.0 bits (71), Expect = 1.9
Identities = 12/21 (57%), Positives = 13/21 (61%)
Query: 128 LPPPPADPVLDLPLPPPPPEP 148
+PPPP P P PPPPP P
Sbjct: 552 MPPPPPPPPPPPPPPPPPPPP 572
Score = 30.4 bits (67), Expect = 5.5
Identities = 12/20 (60%), Positives = 12/20 (60%)
Query: 129 PPPPADPVLDLPLPPPPPEP 148
PPPP P P PPPPP P
Sbjct: 556 PPPPPPPPPPPPPPPPPPLP 575
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 78.6 bits (192), Expect = 2e-14
Identities = 81/253 (32%), Positives = 97/253 (38%), Gaps = 58/253 (22%)
Query: 456 TGPKTGTTQPNGQIPQATHSVSAVLQEAQRHAETSKDKKPALGNHHDPAVPRAPHAPKSS 515
TG G+ P+ ++P T S + + R TS+ A P VP P P +
Sbjct: 122 TGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPP--PPTP 179
Query: 516 LPPPPPVRRSSDTSGSPATPLKAKG--TGGGGLP--APPDDFLPPPPPPPPLDDPELPPP 571
PPPPP+ +S TPL + G LP APP PPPPPPPP P PPP
Sbjct: 180 PPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPP---PPTPPP 236
Query: 572 PP------DFMEPP-------PDFVPP----PPPSYAGI-------AGSELPPPPPPPPA 607
P D P P PP PP Y G+ A PP PPPP
Sbjct: 237 LPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPL 296
Query: 608 PAPAPV-PDSARPPPAV-------AKRPPVPPKRQENPGHPGGAGG----------GEQD 649
P A P ++ P P + PP+PPK P AG G Q
Sbjct: 297 PPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQP 356
Query: 650 FMSDLMKALQKKR 662
F LQKKR
Sbjct: 357 F-------LQKKR 362
Score = 74.7 bits (182), Expect = 3e-13
Identities = 55/162 (33%), Positives = 67/162 (41%), Gaps = 25/162 (15%)
Query: 502 DPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTG------GGGLPAPPDDFLP 555
D A + P S P P R + T P P + G G APP +P
Sbjct: 116 DVAGGKTGQGPGSRAPSP---RLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVP 172
Query: 556 PPPPP-PPLDDPELPPPPPDFMEPPPDFVPPPPPSYAG---IAGSEL---PPPPPPPPAP 608
PPPP PP P LPPP P V PP P G + + PPPPPPPP P
Sbjct: 173 APPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPP 232
Query: 609 APAPVPDSA-------RPPPAVAKRPPVPPKRQENP--GHPG 641
P P+P ++ +P A PP+PP P G+PG
Sbjct: 233 TPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPG 274
Score = 50.1 bits (118), Expect = 7e-06
Identities = 57/198 (28%), Positives = 64/198 (32%), Gaps = 65/198 (32%)
Query: 503 PAVPRAPHAPKSSLPP-PPPVRRSSDTSGSPATPLKAK--------------GTGGGGLP 547
P VP AP P PP PPP+ +S S P A G GL
Sbjct: 217 PPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLK 276
Query: 548 APP----DDFLPPPPPPPPLDD-------------------------PELPPPPPDFMEP 578
A P D PP PPPPL P LPP P F P
Sbjct: 277 AEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAP 336
Query: 579 PPDF------VPPPPPSYA-----------GIAGSELPPPPPPPPAPAPAPVPD-SARPP 620
P PP PP G G +L PPP P PA +P + S++
Sbjct: 337 PQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAP---PARSPTTELSSKSQ 393
Query: 621 PAVAKRPPVPPKRQENPG 638
A A P P Q G
Sbjct: 394 QATAWTPTQQPGGQLRNG 411
Score = 42.0 bits (97), Expect = 0.002
Identities = 21/50 (42%), Positives = 24/50 (48%), Gaps = 13/50 (26%)
Query: 568 LPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSA 617
+P PPP PPP PPPPP L PPPPPP+ P S+
Sbjct: 1 MPVPPP----PPPPLPPPPPP---------LGAPPPPPPSAPPVSTDTSS 37
Score = 42.0 bits (97), Expect = 0.002
Identities = 20/34 (58%), Positives = 20/34 (58%), Gaps = 10/34 (29%)
Query: 556 PPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPS 589
PPPPPPPL PPPPP P PPPPPS
Sbjct: 4 PPPPPPPL-----PPPPPPLGAP-----PPPPPS 27
Score = 40.4 bits (93), Expect = 0.005
Identities = 16/30 (53%), Positives = 16/30 (53%)
Query: 600 PPPPPPPAPAPAPVPDSARPPPAVAKRPPV 629
P PPPPP P P P P PPP PPV
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPV 31
Score = 39.3 bits (90), Expect = 0.012
Identities = 17/28 (60%), Positives = 18/28 (64%), Gaps = 2/28 (7%)
Query: 546 LPAPPDDFLPPPPPPPPLDDPELPPPPP 573
+P PP P PPPPPPL P PPPPP
Sbjct: 1 MPVPPPPPPPLPPPPPPLGAP--PPPPP 26
Score = 37.7 bits (86), Expect = 0.034
Identities = 21/53 (39%), Positives = 23/53 (43%), Gaps = 15/53 (28%)
Query: 566 PELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSAR 618
P PPPPP +PPPPP PPPPPP AP + S R
Sbjct: 2 PVPPPPPPP--------LPPPPPPLGA-------PPPPPPSAPPVSTDTSSLR 39
Score = 35.0 bits (79), Expect = 0.22
Identities = 16/31 (51%), Positives = 16/31 (51%), Gaps = 8/31 (25%)
Query: 600 PPPPPPPAPAPAPVPDSARPPPAVAKRPPVP 630
PPPPPPP P P PPP A PP P
Sbjct: 4 PPPPPPPLPPP--------PPPLGAPPPPPP 26
Score = 33.9 bits (76), Expect = 0.50
Identities = 19/64 (29%), Positives = 27/64 (42%), Gaps = 7/64 (10%)
Query: 599 PPPPPPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGAGGGEQDFMSDLMKAL 658
PPPPPP P P P P A PPP P PP + G ++D+ +
Sbjct: 5 PPPPPPLPPPPP---PLGAPPPPP----PSAPPVSTDTSSLRRADPKGRSALLADIQQGT 57
Query: 659 QKKR 662
+ ++
Sbjct: 58 RLRK 61
Score = 31.2 bits (69), Expect = 3.2
Identities = 15/31 (48%), Positives = 17/31 (54%), Gaps = 6/31 (19%)
Query: 601 PPPPPPAPAPAPVPDSARPPPAVAKRPPVPP 631
P PPPP P P+P PPP + PP PP
Sbjct: 2 PVPPPP---PPPLPP---PPPPLGAPPPPPP 26
Score = 30.8 bits (68), Expect = 4.2
Identities = 15/34 (44%), Positives = 18/34 (52%), Gaps = 2/34 (5%)
Query: 128 LPPPPADPVLDLPLPPPPPEPLSQEEEEAQAKAD 161
LPPPP P L P PPPP P + + +AD
Sbjct: 11 LPPPP--PPLGAPPPPPPSAPPVSTDTSSLRRAD 42
Score = 29.6 bits (65), Expect = 9.4
Identities = 12/21 (57%), Positives = 12/21 (57%)
Query: 129 PPPPADPVLDLPLPPPPPEPL 149
PP P P P PPPPP PL
Sbjct: 166 PPRPNVPAPPPPTPPPPPPPL 186
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 76.3 bits (186), Expect = 9e-14
Identities = 54/149 (36%), Positives = 59/149 (39%), Gaps = 12/149 (8%)
Query: 503 PAVPRAPHAPKSSLPP----PPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPP 558
P P P P PP PPP+ + P P+ G G P P LPP P
Sbjct: 240 PLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGP---LPPGP 296
Query: 559 PPPP--LDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPP---PPPPPPAPAPAPV 613
PPP P PPPP PPP PP PP G + PP P PPP AP PAP
Sbjct: 297 PPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPH 356
Query: 614 PDSARPPPAVAKRPPVPPKRQENPGHPGG 642
+ A PP P R P P G
Sbjct: 357 VNPAFFPPPTNSGMPTSDSRGPPPTDPYG 385
Score = 70.1 bits (170), Expect = 6e-12
Identities = 57/151 (37%), Positives = 65/151 (43%), Gaps = 21/151 (13%)
Query: 504 AVPRAPHAPKSSLP--PPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPP 561
AVP P + P PPPP P PL G G P PP LPPP P
Sbjct: 210 AVPGGDRFPGPAGPGGPPPPFPAGQTP---PRPPLGPPGPPGPPGPPPPGQVLPPPLAGP 266
Query: 562 PLDDPELPPPP-----PDFMEPPPDFVPPPPPSYAGIAGSELPP-PPPPPPAPAPAPVPD 615
P + + PPPP F +PP +PP PP + G PP PPPP P P P P
Sbjct: 267 P-NRGDRPPPPVLFPGQPFGQPPLGPLPPGPPP--PVPGYGPPPGPPPPQQGPPPPPGPF 323
Query: 616 SARPPPAVAKRPPV---PPKRQENPGHPGGA 643
RPP + PP+ PP PG P GA
Sbjct: 324 PPRPPGPLG--PPLTLAPPPHL--PGPPPGA 350
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 75.9 bits (185), Expect = 1e-13
Identities = 50/133 (37%), Positives = 55/133 (41%), Gaps = 18/133 (13%)
Query: 503 PAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPP-- 560
PA P P P + LPP PP P P + G GL P LPP PPP
Sbjct: 417 PAPPLRPPGPPTGLPPGPP----------PGAPPFLRPPGMPGLRGPLPRLLPPGPPPGR 466
Query: 561 ----PPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPV-PD 615
PP P LPP PP PPP PP PP + PP PP PAP + P
Sbjct: 467 PPGPPPGPPPGLPPGPPP-RGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPP 525
Query: 616 SARPPPAVAKRPP 628
+ P P V PP
Sbjct: 526 APLPNPGVLSAPP 538
Score = 63.5 bits (153), Expect = 6e-10
Identities = 43/106 (40%), Positives = 44/106 (41%), Gaps = 18/106 (16%)
Query: 549 PPDDFLPPPPP-PPPLDDPELPP-----PPPDFMEPPPDFVPP--PPPSYAGIAGSE--- 597
PP PP P PPPL P PP PP PP PP PP G+ G
Sbjct: 398 PPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRL 457
Query: 598 LPPPPPP--PPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPG 641
LPP PPP PP P P P P PP P PP R P PG
Sbjct: 458 LPPGPPPGRPPGPPPGPPPGLPPGPP-----PRGPPPRLPPPAPPG 498
Score = 62.0 bits (149), Expect = 2e-09
Identities = 53/171 (30%), Positives = 65/171 (38%), Gaps = 31/171 (18%)
Query: 481 QEAQRHAETSKDKKPALGNHHDPAVPRAPHAPKSSLPP---PPPVRRSSDTSGSPATPLK 537
Q ++H E S + + A P++ + PP PPP+ PA PL+
Sbjct: 369 QSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPL------GPPPAPPLR 422
Query: 538 AKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPP-PDFMEPPPDFVPPPPPSYAGIAGS 596
P PP P PPP P P L PP P P P +PP PP G
Sbjct: 423 P--------PGPPTGLPPGPPPGAP---PFLRPPGMPGLRGPLPRLLPPGPPP-GRPPGP 470
Query: 597 ELPPPPPPPPAP--------APAPVPDSARPP-PAVAKRPPVPPKRQENPG 638
PPP PP P P P P PP P + + P VPP PG
Sbjct: 471 PPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPG 521
Score = 52.4 bits (124), Expect = 1e-06
Identities = 35/94 (37%), Positives = 40/94 (42%), Gaps = 16/94 (17%)
Query: 555 PPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPP--PPAPAPAP 612
P PP + P +P PPP P P PP PP+ LPP PPP PP P
Sbjct: 394 PQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPT-------GLPPGPPPGAPPFLRPPG 446
Query: 613 VPDSARPPPAVAKRPPVPPKRQENPGHPGGAGGG 646
+P P P + PP PP PG P G G
Sbjct: 447 MPGLRGPLPRLL--PPGPP-----PGRPPGPPPG 473
Score = 37.4 bits (85), Expect = 0.045
Identities = 23/75 (30%), Positives = 30/75 (40%), Gaps = 14/75 (18%)
Query: 505 VPRAPHAPKSSL--------PPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPP 556
+P PHAP + L PP + + + G P + G G+P P PP
Sbjct: 141 LPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPP 200
Query: 557 PPPPPPLDDPELPPP 571
PPP P PPP
Sbjct: 201 GPPPGP------PPP 209
Score = 30.0 bits (66), Expect = 7.2
Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 18/94 (19%)
Query: 554 LPPPPPPPPLDDPELP-PPPPDFMEPPPDFVPPPPP-SYAGIAGSELP--PPPPPPPAPA 609
+P P + D LP PP ++ + PP S + G +P PP PP P
Sbjct: 144 MPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPP 203
Query: 610 PAPVPDSARPPPAVAK--------RPPVPPKRQE 635
P P PPP V + +PP+R++
Sbjct: 204 PGP------PPPQVVQMYGRKVGFALDLPPRRRD 231
>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
sapiens]
Length = 406
Score = 75.5 bits (184), Expect = 1e-13
Identities = 53/145 (36%), Positives = 62/145 (42%), Gaps = 12/145 (8%)
Query: 495 PALGNHHDPAVPRAPHAPKSSLPPPPP-VRRSSDTSGSPATPLKAKGTGGGGLPAPPDDF 553
PAL H P +PR P P +PP PP V +P P+ G P PP
Sbjct: 231 PALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPR 290
Query: 554 LPPPPPPPPLDD-PELPPPPPDFMEPPPDFVPPPPPSYAGIAGSEL------PPPPPPPP 606
+ P PP PP+ P PP P PP VPP PP G + PP P PP
Sbjct: 291 MAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPP 350
Query: 607 APAPAPVPDSARPPPAVAKRPPVPP 631
P AP+P P P +A PP PP
Sbjct: 351 GPPMAPLP----PGPPMAPLPPGPP 371
Score = 53.9 bits (128), Expect = 5e-07
Identities = 41/117 (35%), Positives = 48/117 (41%), Gaps = 19/117 (16%)
Query: 542 GGGGLPAPPDD------FLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAG 595
GG AP D +P P PP L P +PP PP PP + P PP G
Sbjct: 220 GGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPG 279
Query: 596 SELPPPPPPPPAPAPAP--VPDSARPP----------PAVAKRPPVPPKRQENPGHP 640
S + P PP P AP P P + PP P +A PP PP + PG P
Sbjct: 280 SRMAPVPPGP-RMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPP 335
Score = 46.2 bits (108), Expect = 1e-04
Identities = 35/98 (35%), Positives = 39/98 (39%), Gaps = 10/98 (10%)
Query: 503 PAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGL----PAPPDDFLPPPP 558
P P P AP PP PV + P P A+ G + P PP LPP P
Sbjct: 293 PVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGP 352
Query: 559 PPPPLDDPELPPPPPDFMEPP-PDFVPPPPPSYAGIAG 595
P PL PP PP PP P P PP S+ G
Sbjct: 353 PMAPL-----PPGPPMAPLPPGPPMAPLPPRSHVPHTG 385
Score = 32.3 bits (72), Expect = 1.4
Identities = 22/50 (44%), Positives = 25/50 (50%), Gaps = 6/50 (12%)
Query: 597 ELPPPP----PPPPAPAPAPVPDSARPPPA-VAKRPPVPPKRQENPGHPG 641
+LP PP PP P P P VP RPP A + PVPP + P PG
Sbjct: 240 QLPRPPVLPVPPMP-PRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPG 288
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 75.1 bits (183), Expect = 2e-13
Identities = 47/135 (34%), Positives = 56/135 (41%), Gaps = 19/135 (14%)
Query: 498 GNHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPP 557
G+ P A AP ++ PPPPP+ P P + APP P P
Sbjct: 524 GSPSPDLAPAAEPAPGAAPPPPPPL---------PGLPSPQEAPPSAPPQAPPLPGSPEP 574
Query: 558 PPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSA 617
PP PPL +LPPPPP PPPPP G PPPPPPP P A +
Sbjct: 575 PPAPPLPG-DLPPPPPP---------PPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDS 624
Query: 618 RPPPAVAKRPPVPPK 632
P V + P+ K
Sbjct: 625 ELGPGVKAKKPIQTK 639
Score = 72.0 bits (175), Expect = 2e-12
Identities = 60/211 (28%), Positives = 73/211 (34%), Gaps = 31/211 (14%)
Query: 468 QIPQATHSVSAVLQEAQRHAETSKDKKPALGNHHDPAVPRAPHAPKSSLPPPPP------ 521
Q+ QA + + + ++P PA P P A + +
Sbjct: 432 QLSQARKELETLRERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRI 491
Query: 522 VRRSSDTSGSPATPLKAKGTGGGGLPAP------PDDFLPP---------PPPPPPLDDP 566
+R D P+ GG P P P L P PPPPPPL P
Sbjct: 492 LRGPGDAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPL--P 549
Query: 567 ELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSARPPPAVAKR 626
LP P E PP P PP + GS PPP PP P P P P PP
Sbjct: 550 GLPSP----QEAPPSAPPQAPP----LPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPV 601
Query: 627 PPVPPKRQENPGHPGGAGGGEQDFMSDLMKA 657
PP PP PG P A G + +KA
Sbjct: 602 PPPPPPPPPPPGGPPDALGRRDSELGPGVKA 632
Score = 35.4 bits (80), Expect = 0.17
Identities = 13/20 (65%), Positives = 14/20 (70%)
Query: 129 PPPPADPVLDLPLPPPPPEP 148
PPPP P D P+PPPPP P
Sbjct: 589 PPPPPPPGTDGPVPPPPPPP 608
Score = 32.3 bits (72), Expect = 1.4
Identities = 14/20 (70%), Positives = 15/20 (75%), Gaps = 1/20 (5%)
Query: 130 PPPADPVL-DLPLPPPPPEP 148
PPPA P+ DLP PPPPP P
Sbjct: 574 PPPAPPLPGDLPPPPPPPPP 593
Score = 29.6 bits (65), Expect = 9.4
Identities = 12/20 (60%), Positives = 12/20 (60%)
Query: 129 PPPPADPVLDLPLPPPPPEP 148
P PP P L LPPPPP P
Sbjct: 572 PEPPPAPPLPGDLPPPPPPP 591
>gi|48762693 growth factor receptor-bound protein 10 isoform b [Homo
sapiens]
Length = 548
Score = 74.7 bits (182), Expect = 3e-13
Identities = 70/236 (29%), Positives = 100/236 (42%), Gaps = 42/236 (17%)
Query: 60 EDQDLDALMADLVADISEAEQRTIQAQKES---LQNQHHSAS----------LQASIFSG 106
+D DL+AL+ D+ A + E+ Q ++ LQN H+ S +Q +
Sbjct: 48 DDVDLEALVNDMNASL-ESLYSACSMQSDTVPLLQNGQHARSQPRASGPPRSIQPQVSPR 106
Query: 107 A-ASLGYGTNVAATGISQYEDDLPPPPADPVLDLPLP-------PPPPEPLSQEEEEAQA 158
++ A Q ED + P + P P PP P S +A A
Sbjct: 107 QRVQRSQPVHILAVRRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAA 166
Query: 159 KADKIKLALEKLKEAKVKKLVVKVHMNDNSTKSLMVDERQLARDVLDNLFEKTHCDCNVD 218
K D VKV D ++K + + ARD+ L K+HC +
Sbjct: 167 KQD------------------VKVFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDDNS 208
Query: 219 WCLYEIYPELQIERFFEDHENVVEVLSDWTRDTENKILFLEKEEKYAVFKNPQNFY 274
W L E +P L +ER EDHE VV+V S T +E+K LF + KY FKNP NF+
Sbjct: 209 WTLVEHHPHLGLERCLEDHELVVQVES--TMASESKFLFRKNYAKYEFFKNPMNFF 262
Score = 57.4 bits (137), Expect = 4e-08
Identities = 27/88 (30%), Positives = 46/88 (52%)
Query: 351 RDLACFIQFENVNIYYGTQHKMKYKAPTDYCFVLKHPQIQKESQYIKYLCCDDTRTLNQW 410
R L E+ NI+ + +Y APTD+ +K +++ E++ ++ LC +D +T W
Sbjct: 285 RHLQLLADLEDSNIFSLIAGRKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCW 344
Query: 411 VMGIRIAKYGKTLYDNYQRAVAKAGLAS 438
+ R+ KYG LY NY+ + L S
Sbjct: 345 MTAFRLLKYGMLLYQNYRIPQQRKALLS 372
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 74.7 bits (182), Expect = 3e-13
Identities = 65/197 (32%), Positives = 77/197 (39%), Gaps = 44/197 (22%)
Query: 442 NLGTVNAAAPAQPSTGPKTGTTQPNGQIPQATHSVSAVLQEAQRHAETSKDKKPALGNHH 501
NL + Q +T PK GQ P A A E HA++ K +
Sbjct: 363 NLDQSQRGSSPQNTTTPKPSV---EGQQPAA-----AAACEPVDHAQSESILKVSQ---- 410
Query: 502 DPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPP 561
PRA S+ PPPPP +S P P LP+ LP PPPP
Sbjct: 411 ----PRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPP-----PLPSVGAKALPTAPPPP 461
Query: 562 PLDD--------PELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPP--------P 605
PL P LPPP P E F+PPPPP G+ PPPPPP P
Sbjct: 462 PLPGLGAMAPPAPPLPPPLPGSCE----FLPPPPPPLPGLG---CPPPPPPLLPGMGWGP 514
Query: 606 PAPAPAPVPDSARPPPA 622
P P P +P + PP A
Sbjct: 515 PPPPPPLLPCTCSPPVA 531
Score = 63.9 bits (154), Expect = 4e-10
Identities = 43/116 (37%), Positives = 47/116 (40%), Gaps = 22/116 (18%)
Query: 555 PPPPPPPPL-----DDPELPPPPPDF----MEPPPDFVPPPPPSYAGIAGSELPPPPPPP 605
PPPPPPPPL +P PPPPP + P PPPP G PP PPP
Sbjct: 421 PPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPL 480
Query: 606 PA------PAPAPVPDSARPPPAVA-------KRPPVPPKRQENPGHPGGAGGGEQ 648
P P P P+P PPP PP PP P AGG E+
Sbjct: 481 PGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGGMEE 536
Score = 47.0 bits (110), Expect = 6e-05
Identities = 36/90 (40%), Positives = 36/90 (40%), Gaps = 25/90 (27%)
Query: 495 PALGNHHDPAVPRAPHAPKSS--LPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDD 552
P LG PA P P P S LPPPPP PL G G P PP
Sbjct: 464 PGLGAMAPPAPPLPPPLPGSCEFLPPPPP-------------PLP-----GLGCPPPPPP 505
Query: 553 FLP-----PPPPPPPLDDPELPPPPPDFME 577
LP PPPPPPPL PP ME
Sbjct: 506 LLPGMGWGPPPPPPPLLPCTCSPPVAGGME 535
Score = 38.5 bits (88), Expect = 0.020
Identities = 24/65 (36%), Positives = 28/65 (43%), Gaps = 20/65 (30%)
Query: 594 AGSELPPPPP---------PPPAPAPAPVPD-------SARPPPAV----AKRPPVPPKR 633
A + PPPPP PPP P P P+P +A PPP + A PP PP
Sbjct: 418 ASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLP 477
Query: 634 QENPG 638
PG
Sbjct: 478 PPLPG 482
Score = 32.0 bits (71), Expect = 1.9
Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 4/67 (5%)
Query: 87 KESLQNQHHSASLQASIFSGAASLGYGTNVAATGISQYEDDLPPPPADPVLD----LPLP 142
K S++ Q +A+ A S + Q PPPP P+L P P
Sbjct: 380 KPSVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPP 439
Query: 143 PPPPEPL 149
PPPP PL
Sbjct: 440 PPPPPPL 446
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 74.7 bits (182), Expect = 3e-13
Identities = 65/197 (32%), Positives = 77/197 (39%), Gaps = 44/197 (22%)
Query: 442 NLGTVNAAAPAQPSTGPKTGTTQPNGQIPQATHSVSAVLQEAQRHAETSKDKKPALGNHH 501
NL + Q +T PK GQ P A A E HA++ K +
Sbjct: 363 NLDQSQRGSSPQNTTTPKPSV---EGQQPAA-----AAACEPVDHAQSESILKVSQ---- 410
Query: 502 DPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPP 561
PRA S+ PPPPP +S P P LP+ LP PPPP
Sbjct: 411 ----PRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPP-----PLPSVGAKALPTAPPPP 461
Query: 562 PLDD--------PELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPP--------P 605
PL P LPPP P E F+PPPPP G+ PPPPPP P
Sbjct: 462 PLPGLGAMAPPAPPLPPPLPGSCE----FLPPPPPPLPGLG---CPPPPPPLLPGMGWGP 514
Query: 606 PAPAPAPVPDSARPPPA 622
P P P +P + PP A
Sbjct: 515 PPPPPPLLPCTCSPPVA 531
Score = 63.9 bits (154), Expect = 4e-10
Identities = 43/116 (37%), Positives = 47/116 (40%), Gaps = 22/116 (18%)
Query: 555 PPPPPPPPL-----DDPELPPPPPDF----MEPPPDFVPPPPPSYAGIAGSELPPPPPPP 605
PPPPPPPPL +P PPPPP + P PPPP G PP PPP
Sbjct: 421 PPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPL 480
Query: 606 PA------PAPAPVPDSARPPPAVA-------KRPPVPPKRQENPGHPGGAGGGEQ 648
P P P P+P PPP PP PP P AGG E+
Sbjct: 481 PGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGGMEE 536
Score = 47.0 bits (110), Expect = 6e-05
Identities = 36/90 (40%), Positives = 36/90 (40%), Gaps = 25/90 (27%)
Query: 495 PALGNHHDPAVPRAPHAPKSS--LPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDD 552
P LG PA P P P S LPPPPP PL G G P PP
Sbjct: 464 PGLGAMAPPAPPLPPPLPGSCEFLPPPPP-------------PLP-----GLGCPPPPPP 505
Query: 553 FLP-----PPPPPPPLDDPELPPPPPDFME 577
LP PPPPPPPL PP ME
Sbjct: 506 LLPGMGWGPPPPPPPLLPCTCSPPVAGGME 535
Score = 38.5 bits (88), Expect = 0.020
Identities = 24/65 (36%), Positives = 28/65 (43%), Gaps = 20/65 (30%)
Query: 594 AGSELPPPPP---------PPPAPAPAPVPD-------SARPPPAV----AKRPPVPPKR 633
A + PPPPP PPP P P P+P +A PPP + A PP PP
Sbjct: 418 ASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLP 477
Query: 634 QENPG 638
PG
Sbjct: 478 PPLPG 482
Score = 32.0 bits (71), Expect = 1.9
Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 4/67 (5%)
Query: 87 KESLQNQHHSASLQASIFSGAASLGYGTNVAATGISQYEDDLPPPPADPVLD----LPLP 142
K S++ Q +A+ A S + Q PPPP P+L P P
Sbjct: 380 KPSVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPP 439
Query: 143 PPPPEPL 149
PPPP PL
Sbjct: 440 PPPPPPL 446
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 73.9 bits (180), Expect = 4e-13
Identities = 64/201 (31%), Positives = 73/201 (36%), Gaps = 39/201 (19%)
Query: 457 GPKTGTTQPNGQIPQATHSVSAVLQEAQRHAETSKDKKPALGNHHDPAVPRAPHAPKSSL 516
GP G + P IP Q+ + P H P PH +
Sbjct: 48 GPGPGQSGPKPPIPPPP-------PHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQ-- 98
Query: 517 PPPPPVRRSSDTSGSPATPLKAKGTG---GGGLPAPPDDFLPPPPPP----PPLDDP-EL 568
PPPPP S P+ A+G G G G P PP PP PP P
Sbjct: 99 PPPPPQDSSK--------PVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPT 150
Query: 569 PPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPP----PPPPPAPAPAPVPDSARPPPAVA 624
P PPP PP PP PPS +G PP PPPPPA P P P + P
Sbjct: 151 PTPPPAVTSAPPGAPPPTPPS----SGVPTTPPQAGGPPPPPAAVPGPGPGPKQGP---- 202
Query: 625 KRPPVPPKRQENPGHPGGAGG 645
P PK + PG P GG
Sbjct: 203 --GPGGPKGGKMPGGPKPGGG 221
Score = 68.2 bits (165), Expect = 2e-11
Identities = 47/159 (29%), Positives = 57/159 (35%), Gaps = 26/159 (16%)
Query: 512 PKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPP----------- 560
PK +PPPPP ++ P + P P PPPPP
Sbjct: 56 PKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGP 115
Query: 561 ---------PPLDDPELPPPPPDFMEPP---PDFVPPPPPSYAGIAGSELPPPPPPPPAP 608
PP P PP PP P P PPP+ PPP PP +
Sbjct: 116 GPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGA--PPPTPPSSG 173
Query: 609 APAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGAGGGE 647
P P + PPP A P P ++ PG PGG GG+
Sbjct: 174 VPTTPPQAGGPPPPPAAVPGPGPGPKQGPG-PGGPKGGK 211
Score = 65.5 bits (158), Expect = 2e-10
Identities = 59/192 (30%), Positives = 75/192 (39%), Gaps = 31/192 (16%)
Query: 481 QEAQRHAETSKDKKPALGNHHDPA--VPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKA 538
Q+ Q KP + PA V AP A S+ P PP TSG+P
Sbjct: 95 QQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPP------TSGAPP----- 143
Query: 539 KGTGGGGLPAPPDDFL--PP--PPPPPPLDDPELPPPPPDFMEPPPDFVPPP------PP 588
G+G G P PP PP PPP PP PP PPP VP P P
Sbjct: 144 -GSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGP 202
Query: 589 SYAGIAGSELPPPPPPPPAPAPAPVPDSARPP------PAVAKRPPVPPKRQENPG-HPG 641
G G ++P P P P + +PP P ++ P +Q + G PG
Sbjct: 203 GPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPG 262
Query: 642 GAGGGEQDFMSD 653
G GG ++ +SD
Sbjct: 263 GPGGRSEEKISD 274
Score = 62.4 bits (150), Expect = 1e-09
Identities = 39/109 (35%), Positives = 46/109 (42%), Gaps = 11/109 (10%)
Query: 544 GGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPP-PPPSYAGIAGSELPPPP 602
G + P P PP PPP + PPP +PPP PP PP + + PPPP
Sbjct: 45 GPMGPGPGQSGPKPPIPPPPPHQQQQQPPP--QQPPPQQPPPHQPPPHPQPHQQQQPPPP 102
Query: 603 P-----PPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGAGGG 646
P P A P P P PPA + PP P G P G+G G
Sbjct: 103 PQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATP---PTSGAPPGSGPG 148
Score = 58.9 bits (141), Expect = 1e-08
Identities = 54/157 (34%), Positives = 58/157 (36%), Gaps = 50/157 (31%)
Query: 519 PPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPP------PPPLDDPELPPPP 572
PPP + G P P G G G P PP +PPPPP PPP P PPP
Sbjct: 34 PPPGMGLNQNRG-PMGP----GPGQSG-PKPP---IPPPPPHQQQQQPPPQQPPPQQPPP 84
Query: 573 PDFMEPPP-----DFVPPPPP-------------------SYAGIAGSELPPPPPP---- 604
+PPP PPPP A A S PP PP
Sbjct: 85 H---QPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGA 141
Query: 605 PPAPAPAPVPDSARPPPAVAKRPP-VPPKRQENPGHP 640
PP P P P PPPAV PP PP + G P
Sbjct: 142 PPGSGPGPTP---TPPPAVTSAPPGAPPPTPPSSGVP 175
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.133 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,143,685
Number of Sequences: 37866
Number of extensions: 3053643
Number of successful extensions: 96302
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1369
Number of HSP's successfully gapped in prelim test: 1604
Number of HSP's that attempted gapping in prelim test: 20368
Number of HSP's gapped (non-prelim): 28914
length of query: 666
length of database: 18,247,518
effective HSP length: 109
effective length of query: 557
effective length of database: 14,120,124
effective search space: 7864909068
effective search space used: 7864909068
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.