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Search of human proteins with 56117820
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56117820 testis and skeletal muscle-specific dual
specificity phosphatase isoform 2 [Homo sapiens]
(248 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56117820 testis and skeletal muscle-specific dual specificity... 497 e-141
gi|56117822 testis and skeletal muscle-specific dual specificity... 397 e-111
gi|56237018 testis and skeletal muscle-specific dual specificity... 396 e-111
gi|56117818 muscle-restricted dual specificity phosphatase isofo... 197 7e-51
gi|51491914 dual specificity phosphatase and pro isomerase domai... 181 5e-46
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 167 1e-41
gi|122937243 dual specificity phosphatase 27 [Homo sapiens] 150 1e-36
gi|4758208 dual specificity phosphatase 3 [Homo sapiens] 130 8e-31
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 80 1e-15
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 80 1e-15
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 77 1e-14
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 76 2e-14
gi|239582767 slingshot homolog 3 [Homo sapiens] 74 1e-13
gi|225703077 dual specificity phosphatase 21 [Homo sapiens] 74 2e-13
gi|51093845 dual specificity phosphatase 18 [Homo sapiens] 73 3e-13
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 71 1e-12
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 70 1e-12
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 70 2e-12
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 65 5e-11
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 65 7e-11
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 64 2e-10
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 63 3e-10
gi|194733759 serine/threonine/tyrosine interacting protein [Homo... 63 3e-10
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ... 63 3e-10
gi|75750526 dual specificity phosphatase 28 [Homo sapiens] 62 4e-10
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 61 1e-09
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 60 1e-09
gi|37674210 slingshot 2 [Homo sapiens] 60 2e-09
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 59 4e-09
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 59 5e-09
>gi|56117820 testis and skeletal muscle-specific dual specificity
phosphatase isoform 2 [Homo sapiens]
Length = 248
Score = 497 bits (1279), Expect = e-141
Identities = 248/248 (100%), Positives = 248/248 (100%)
Query: 1 MAETSLPELGGEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLFIGDAMDSLQKQDLR 60
MAETSLPELGGEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLFIGDAMDSLQKQDLR
Sbjct: 1 MAETSLPELGGEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLFIGDAMDSLQKQDLR 60
Query: 61 RPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQL 120
RPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQL
Sbjct: 61 RPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQL 120
Query: 121 GITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVP 180
GITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVP
Sbjct: 121 GITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVP 180
Query: 181 QGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNR 240
QGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNR
Sbjct: 181 QGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNR 240
Query: 241 LGRETGRF 248
LGRETGRF
Sbjct: 241 LGRETGRF 248
>gi|56117822 testis and skeletal muscle-specific dual specificity
phosphatase isoform 3 [Homo sapiens]
Length = 291
Score = 397 bits (1019), Expect = e-111
Identities = 203/222 (91%), Positives = 206/222 (92%), Gaps = 3/222 (1%)
Query: 28 LRAGKSSC-SRVDEVWPNLFIGDAMDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLW 86
L+A ++C S W MDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLW
Sbjct: 72 LKASSTNCPSEKCTAWARY--SHRMDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLW 129
Query: 87 VRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMS 146
VRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMS
Sbjct: 130 VRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMS 189
Query: 147 LEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMIC 206
LEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMIC
Sbjct: 190 LEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMIC 249
Query: 207 ENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRETGRF 248
ENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRETGRF
Sbjct: 250 ENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRETGRF 291
>gi|56237018 testis and skeletal muscle-specific dual specificity
phosphatase isoform 6 [Homo sapiens]
Length = 198
Score = 396 bits (1018), Expect = e-111
Identities = 198/198 (100%), Positives = 198/198 (100%)
Query: 51 MDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYA 110
MDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYA
Sbjct: 1 MDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYA 60
Query: 111 ARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVA 170
ARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVA
Sbjct: 61 ARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVA 120
Query: 171 RYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGF 230
RYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGF
Sbjct: 121 RYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGF 180
Query: 231 LRQLQVLDNRLGRETGRF 248
LRQLQVLDNRLGRETGRF
Sbjct: 181 LRQLQVLDNRLGRETGRF 198
Score = 38.5 bits (88), Expect = 0.005
Identities = 23/68 (33%), Positives = 40/68 (58%), Gaps = 3/68 (4%)
Query: 7 PELGGEDKATPC--PSILELEELLRAGKSSC-SRVDEVWPNLFIGDAMDSLQKQDLRRPK 63
P++ G +A+P P++ L+ LL +++ + +DEVWP+LF+GDA + K L +
Sbjct: 12 PKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLG 71
Query: 64 IHGAVQAS 71
I V A+
Sbjct: 72 ITHVVNAA 79
>gi|56117818 muscle-restricted dual specificity phosphatase isoform
1 [Homo sapiens]
Length = 188
Score = 197 bits (501), Expect = 7e-51
Identities = 118/241 (48%), Positives = 139/241 (57%), Gaps = 59/241 (24%)
Query: 1 MAETSLPELGGEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLFIGDAMDSLQKQDLR 60
MAETSLPELGGEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLFIGD
Sbjct: 1 MAETSLPELGGEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLFIGD----------- 49
Query: 61 RPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQL 120
AAT N+ E+W +L
Sbjct: 50 -----------------------------AATANNRFELW------------------KL 62
Query: 121 GITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVP 180
GITHV+NAA G FY G S+ Y G+ A D P FD+S YF A +I AL+ P
Sbjct: 63 GITHVLNAAHKGLYCQGGPDFY-GSSVSYLGVPAHDLPDFDISAYFSSAADFIHRALNTP 121
Query: 181 QGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNR 240
+VLVHC +GVSRSATLVLA+LM+ + ++L +A+ TV+ HR + PN GFL QL LD +
Sbjct: 122 GAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVFPNRGFLHQLCRLDQQ 181
Query: 241 L 241
L
Sbjct: 182 L 182
>gi|51491914 dual specificity phosphatase and pro isomerase domain
containing 1 [Homo sapiens]
Length = 220
Score = 181 bits (459), Expect = 5e-46
Identities = 91/186 (48%), Positives = 126/186 (67%), Gaps = 1/186 (0%)
Query: 62 PKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLG 121
PK+ + Y P L+RL W + + H++EVWP L++GD A D+ +L + G
Sbjct: 22 PKMEEEGEEEDYCTPGAFELERLFW-KGSPQYTHVNEVWPKLYIGDEATALDRYRLQKAG 80
Query: 122 ITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQ 181
THV+NAA G++ VDTG +YR M ++Y+G+EADD P FDLSV+F P A +I ALS
Sbjct: 81 FTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRALSDDH 140
Query: 182 GRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRL 241
++LVHC MG SRSATLVLA+LMI ++MTLV+AIQ V +R + PN GFL+QL+ LD +L
Sbjct: 141 SKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNRCVLPNRGFLKQLRELDKQL 200
Query: 242 GRETGR 247
++ R
Sbjct: 201 VQQRRR 206
Score = 40.4 bits (93), Expect = 0.001
Identities = 19/51 (37%), Positives = 28/51 (54%)
Query: 11 GEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLFIGDAMDSLQKQDLRR 61
GE++ P ELE L G + V+EVWP L+IGD +L + L++
Sbjct: 28 GEEEDYCTPGAFELERLFWKGSPQYTHVNEVWPKLYIGDEATALDRYRLQK 78
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 167 bits (422), Expect = 1e-41
Identities = 86/161 (53%), Positives = 116/161 (72%), Gaps = 3/161 (1%)
Query: 81 LQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAK 140
L+RLL+ + A NH DEVWP L+LGD A ++ +L +LGITHV+NA+ +++ A
Sbjct: 48 LERLLYTGKTAC-NHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEA- 105
Query: 141 FYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVL 200
Y G+ + Y G+EA D+P FD+S++F A +I ALS P G++LVHCA+GVSRSATLVL
Sbjct: 106 -YEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVL 164
Query: 201 AFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRL 241
A+LM+ ++TLVEAI+ V+ HR I PN GFLRQL LD RL
Sbjct: 165 AYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRL 205
Score = 49.7 bits (117), Expect = 2e-06
Identities = 23/55 (41%), Positives = 35/55 (63%)
Query: 17 PCPSILELEELLRAGKSSCSRVDEVWPNLFIGDAMDSLQKQDLRRPKIHGAVQAS 71
P ++ ELE LL GK++C+ DEVWP L++GD + +++LRR I + AS
Sbjct: 41 PFLNVFELERLLYTGKTACNHADEVWPGLYLGDQDMANNRRELRRLGITHVLNAS 95
>gi|122937243 dual specificity phosphatase 27 [Homo sapiens]
Length = 1158
Score = 150 bits (379), Expect = 1e-36
Identities = 86/209 (41%), Positives = 126/209 (60%), Gaps = 4/209 (1%)
Query: 37 RVDEVWPNLFIGDAMDSLQKQDLRRPKIHGAVQASPYQPPTLASLQR-LLWVRQAATLNH 95
R D P + ++ + L +DL S Y P + LQR L+ RQ A N
Sbjct: 76 RADAECPGML--ESAEQLLVEDLYNRVREKMDDTSLYNTPCVLDLQRALVQDRQEAPWNE 133
Query: 96 IDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEAD 155
+DEVWP++F+ + A +K +L +LGITH++NAA G V TG +FY G+ ++Y G+E D
Sbjct: 134 VDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAAHGT-GVYTGPEFYTGLEIQYLGVEVD 192
Query: 156 DNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAI 215
D P D+S +F + ++ AL +G+VLV MG+SRSA LV+A+LMI NM ++EA+
Sbjct: 193 DFPEVDISQHFRKASEFLDEALLTYRGKVLVSSEMGISRSAVLVVAYLMIFHNMAILEAL 252
Query: 216 QTVQAHRNICPNSGFLRQLQVLDNRLGRE 244
TV+ R I PN GFL+QL+ L+ +L E
Sbjct: 253 MTVRKKRAIYPNEGFLKQLRELNEKLMEE 281
Score = 33.9 bits (76), Expect = 0.14
Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 4/48 (8%)
Query: 16 TPCPSILELEELLRAGKSSC--SRVDEVWPNLFIGDAMDSLQKQDLRR 61
TPC +L+L+ L + + VDEVWPN+FI + ++ K L+R
Sbjct: 112 TPC--VLDLQRALVQDRQEAPWNEVDEVWPNVFIAEKSVAVNKGRLKR 157
>gi|4758208 dual specificity phosphatase 3 [Homo sapiens]
Length = 185
Score = 130 bits (328), Expect = 8e-31
Identities = 71/150 (47%), Positives = 99/150 (66%), Gaps = 2/150 (1%)
Query: 97 DEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGK--FQVDTGAKFYRGMSLEYYGIEA 154
+EV P +++G+A A+D KL +LGITHV+NAA G+ V+T A FY+ + Y GI+A
Sbjct: 31 NEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKA 90
Query: 155 DDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEA 214
+D F+LS YF A +I AL+ GRVLVHC G SRS TLV+A+LM+ + M + A
Sbjct: 91 NDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSA 150
Query: 215 IQTVQAHRNICPNSGFLRQLQVLDNRLGRE 244
+ V+ +R I PN GFL QL L++RL +E
Sbjct: 151 LSIVRQNREIGPNDGFLAQLCQLNDRLAKE 180
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 80.5 bits (197), Expect = 1e-15
Identities = 53/145 (36%), Positives = 81/145 (55%), Gaps = 9/145 (6%)
Query: 98 EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 157
E+ P L+LG AY A + L LGIT ++N ++ + G +Y I +DN
Sbjct: 198 EILPFLYLGSAYHAARRDMLDALGITALLNVSSDC------PNHFEG-HYQYKCIPVEDN 250
Query: 158 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 217
D+S +F+ YI A +GRVLVHC G+SRSAT+ LA+LM+ + + L EA +
Sbjct: 251 HKADISSWFMEAIEYIDAVKDC-RGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEF 309
Query: 218 VQAHRN-ICPNSGFLRQLQVLDNRL 241
V+ R+ I PN F+ QL ++++
Sbjct: 310 VKQRRSIISPNFSFMGQLLQFESQV 334
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 80.5 bits (197), Expect = 1e-15
Identities = 53/145 (36%), Positives = 81/145 (55%), Gaps = 9/145 (6%)
Query: 98 EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 157
E+ P L+LG AY A + L LGIT ++N ++ + G +Y I +DN
Sbjct: 107 EILPFLYLGSAYHAARRDMLDALGITALLNVSSDC------PNHFEG-HYQYKCIPVEDN 159
Query: 158 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 217
D+S +F+ YI A +GRVLVHC G+SRSAT+ LA+LM+ + + L EA +
Sbjct: 160 HKADISSWFMEAIEYIDAVKDC-RGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEF 218
Query: 218 VQAHRN-ICPNSGFLRQLQVLDNRL 241
V+ R+ I PN F+ QL ++++
Sbjct: 219 VKQRRSIISPNFSFMGQLLQFESQV 243
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 77.0 bits (188), Expect = 1e-14
Identities = 58/152 (38%), Positives = 80/152 (52%), Gaps = 10/152 (6%)
Query: 96 IDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEAD 155
I ++ SLFLG A ++ L GIT +VNA ++ + EY +
Sbjct: 27 IAQITSSLFLGRGSVASNRHLLQARGITCIVNAT---IEIPN----FNWPQFEYVKVPLA 79
Query: 156 DNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAI 215
D P + +YF VA I + +S G LVHCA GVSRSATL +A+LM N+ L+EA
Sbjct: 80 DMPHAPIGLYFDTVADKIHS-VSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAY 138
Query: 216 QTVQAHRNIC-PNSGFLRQLQVLDNRL-GRET 245
V+A R + PN GF RQL + +L G+ T
Sbjct: 139 NWVKARRPVIRPNVGFWRQLIDYERQLFGKST 170
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 76.3 bits (186), Expect = 2e-14
Identities = 57/155 (36%), Positives = 78/155 (50%), Gaps = 14/155 (9%)
Query: 98 EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 157
E+ P L+LG AY A K L LGIT ++N +A + G +Y I +DN
Sbjct: 176 EILPFLYLGSAYHASRKDMLDALGITALINVSANC------PNHFEG-HYQYKSIPVEDN 228
Query: 158 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 217
D+S +F +I + + GRV VHC G+SRSAT+ LA+LM + L EA +
Sbjct: 229 HKADISSWFNEAIDFIDSIKNAG-GRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEF 287
Query: 218 VQAHRN-ICPNSGFLRQL-----QVLDNRLGRETG 246
V+ R+ I PN F+ QL QVL E G
Sbjct: 288 VKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAG 322
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 73.9 bits (180), Expect = 1e-13
Identities = 68/217 (31%), Positives = 110/217 (50%), Gaps = 27/217 (12%)
Query: 23 ELEELLRAGKSSCSRVDEVWPNLFIGDAMDSLQKQDLRRP-KIHGAVQASPYQPPTLASL 81
++E+ +RA E+W L + D ++S+ +++R+ ++ + Y+
Sbjct: 270 QMEQAIRA---------ELWKVLDVSD-LESVTSKEIRQALELRLGLPLQQYRD--FIDN 317
Query: 82 QRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKF 141
Q LL V Q + ++P L+LG + A + +L + +TH++N A ++D F
Sbjct: 318 QMLLLVAQR---DRASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAR---EIDN---F 368
Query: 142 YRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQG-RVLVHCAMGVSRSATLVL 200
Y Y+ + D L ++ R+I AA + QG VLVHC MGVSRSA VL
Sbjct: 369 YPER-FTYHNVRLWDEESAQLLPHWKETHRFIEAARA--QGTHVLVHCKMGVSRSAATVL 425
Query: 201 AFLMICENMTLVEAIQTVQAHRNIC-PNSGFLRQLQV 236
A+ M +L +A++ VQ R I PN GFLRQLQ+
Sbjct: 426 AYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQI 462
>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
Length = 190
Score = 73.6 bits (179), Expect = 2e-13
Identities = 53/147 (36%), Positives = 78/147 (53%), Gaps = 9/147 (6%)
Query: 89 QAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLE 148
Q ++ ++ SLFL + AA DK L IT +VNA+ V F+ G ++
Sbjct: 15 QQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNV-----FFEG--IQ 67
Query: 149 YYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICEN 208
Y + D L +F P+A I + + QGR L+HC GVSRSA+L LA+LM +
Sbjct: 68 YIKVPVTDARDSRLYDFFDPIADLIHT-IDMRQGRTLLHCMAGVSRSASLCLAYLMKYHS 126
Query: 209 MTLVEAIQTVQAHRNIC-PNSGFLRQL 234
M+L++A ++ R I PN+GF QL
Sbjct: 127 MSLLDAHTWTKSRRPIIRPNNGFWEQL 153
>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
Length = 188
Score = 72.8 bits (177), Expect = 3e-13
Identities = 50/144 (34%), Positives = 80/144 (55%), Gaps = 9/144 (6%)
Query: 92 TLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYG 151
+++ + ++ SL++ + AA +K L IT V+N + V+ Y ++Y
Sbjct: 16 SVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVS-----VEVVNTLYE--DIQYMQ 68
Query: 152 IEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTL 211
+ D+P L +F P+A +I + + + QGR L+HCA GVSRSA L LA+LM M+L
Sbjct: 69 VPVADSPNSRLCDFFDPIADHIHS-VEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSL 127
Query: 212 VEAIQTVQAHRNIC-PNSGFLRQL 234
++A ++ R I PNSGF QL
Sbjct: 128 LDAHTWTKSCRPIIRPNSGFWEQL 151
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 70.9 bits (172), Expect = 1e-12
Identities = 52/163 (31%), Positives = 79/163 (48%), Gaps = 11/163 (6%)
Query: 86 WVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGM 145
+V+ ++ + + P L LG AA D L + +TH++N A G Y+ +
Sbjct: 56 YVQDLSSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSI 115
Query: 146 SLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMI 205
S+ D P ++ YF +I A G VLVHC GVSR+A +V+ FLM
Sbjct: 116 SIL-------DLPETNILSYFPECFEFIEEAKR-KDGVVLVHCNAGVSRAAAIVIGFLMN 167
Query: 206 CENMTLVEAIQTVQ-AHRNICPNSGFLRQLQVLDNRLGRETGR 247
E + A V+ A +ICPNSGF+ QL+ G+E+ +
Sbjct: 168 SEQTSFTSAFSLVKNARPSICPNSGFMEQLRTYQE--GKESNK 208
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 70.5 bits (171), Expect = 1e-12
Identities = 50/138 (36%), Positives = 69/138 (50%), Gaps = 9/138 (6%)
Query: 98 EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 157
E+ P LFLG + D L GIT V+N +A + + G+ Y I +DN
Sbjct: 175 EILPYLFLGSCSHSSDLQGLQACGITAVLNVSA------SCPNHFEGL-FRYKSIPVEDN 227
Query: 158 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 217
++S +F +I + GRVLVHC G+SRSAT+ LA+LM + L EA
Sbjct: 228 QMVEISAWFQEAIGFIDWVKN-SGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDF 286
Query: 218 VQAHRN-ICPNSGFLRQL 234
V+ R I PN F+ QL
Sbjct: 287 VKQRRGVISPNFSFMGQL 304
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 69.7 bits (169), Expect = 2e-12
Identities = 47/143 (32%), Positives = 78/143 (54%), Gaps = 10/143 (6%)
Query: 94 NHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIE 153
N ++++ P L++G+ ARD +L + +TH+++ D+ G+ +Y I
Sbjct: 3 NGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVH------DSARPMLEGV--KYLCIP 54
Query: 154 ADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVE 213
A D+P +L+ +F ++I + LVHC GVSRS TLV+A++M + +
Sbjct: 55 AADSPSQNLTRHFKESIKFIHECRLRGES-CLVHCLAGVSRSVTLVIAYIMTVTDFGWED 113
Query: 214 AIQTVQAHRNIC-PNSGFLRQLQ 235
A+ TV+A R+ PN GF RQLQ
Sbjct: 114 ALHTVRAGRSCANPNVGFQRQLQ 136
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 65.1 bits (157), Expect = 5e-11
Identities = 59/191 (30%), Positives = 91/191 (47%), Gaps = 29/191 (15%)
Query: 52 DSLQKQDLRRPKIHGAVQAS----PYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGD 107
+SLQ Q+ R ++ G A+ P PT ++ + + P LFLG+
Sbjct: 286 NSLQLQECR--EVGGGASAASSLLPQPIPTTPDIENA----------ELTPILPFLFLGN 333
Query: 108 AYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFY---RGMSLEYYGIEADDNPFFDLSV 164
A+D + +L I +V+N V T Y +G+ Y + A D+ +L
Sbjct: 334 EQDAQDLDTMQRLNIGYVIN-------VTTHLPLYHYEKGL-FNYKRLPATDSNKQNLRQ 385
Query: 165 YFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRN- 223
YF +I A +G +L+HC GVSRSAT+V+A+LM MT+ +A + V+ R
Sbjct: 386 YFEEAFEFIEEAHQCGKG-LLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPI 444
Query: 224 ICPNSGFLRQL 234
I PN F+ QL
Sbjct: 445 ISPNLNFMGQL 455
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 64.7 bits (156), Expect = 7e-11
Identities = 45/138 (32%), Positives = 67/138 (48%), Gaps = 9/138 (6%)
Query: 98 EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 157
E+ P L+LG AY A L L IT ++N + + L Y I +D+
Sbjct: 181 EILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACA-------THLHYKWIPVEDS 233
Query: 158 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 217
D+S +F +I G+VLVHC G+SRS T+ +A+LM + L EA
Sbjct: 234 HTADISSHFQEAIDFIDCVRE-KGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDY 292
Query: 218 VQAHRN-ICPNSGFLRQL 234
++ R+ + PN GF+ QL
Sbjct: 293 IKQRRSMVSPNFGFMGQL 310
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 63.5 bits (153), Expect = 2e-10
Identities = 48/148 (32%), Positives = 74/148 (50%), Gaps = 7/148 (4%)
Query: 98 EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 157
++ P+L+LG A + + L +LGI +++N F + Y I D+
Sbjct: 206 QILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNF-----FEKNGDFHYKQIPISDH 260
Query: 158 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 217
+LS +F +I ALS G VLVHC GVSRS T+ +A+LM +++L +A
Sbjct: 261 WSQNLSRFFPEAIEFIDEALSQNCG-VLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDL 319
Query: 218 VQAHR-NICPNSGFLRQLQVLDNRLGRE 244
V+ + NI PN F+ QL + L E
Sbjct: 320 VKRKKSNISPNFNFMGQLLDFERSLRLE 347
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 62.8 bits (151), Expect = 3e-10
Identities = 52/148 (35%), Positives = 76/148 (51%), Gaps = 16/148 (10%)
Query: 96 IDEVWPSLFLGDAYAARDKSKLIQL---GITHVV----NAAAGKFQVDTGAKFYRGMSLE 148
+ E+ P LFLG Y++ KSKL L GITH++ N A + + F
Sbjct: 29 MQEILPGLFLGP-YSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLF------R 81
Query: 149 YYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICEN 208
Y ++ DNP ++ +F +I +L + G+VLVH G+SRSA V+A++M
Sbjct: 82 YLVLDIADNPVENIIRFFPMTKEFIDGSLQMG-GKVLVHGNAGISRSAAFVIAYIMETFG 140
Query: 209 MTLVEAIQTVQAHR-NICPNSGFLRQLQ 235
M +A VQ R I PN+GF+ QLQ
Sbjct: 141 MKYRDAFAYVQERRFCINPNAGFVHQLQ 168
>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 62.8 bits (151), Expect = 3e-10
Identities = 52/148 (35%), Positives = 76/148 (51%), Gaps = 16/148 (10%)
Query: 96 IDEVWPSLFLGDAYAARDKSKLIQL---GITHVV----NAAAGKFQVDTGAKFYRGMSLE 148
+ E+ P LFLG Y++ KSKL L GITH++ N A + + F
Sbjct: 29 MQEILPGLFLGP-YSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLF------R 81
Query: 149 YYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICEN 208
Y ++ DNP ++ +F +I +L + G+VLVH G+SRSA V+A++M
Sbjct: 82 YLVLDIADNPVENIIRFFPMTKEFIDGSLQMG-GKVLVHGNAGISRSAAFVIAYIMETFG 140
Query: 209 MTLVEAIQTVQAHR-NICPNSGFLRQLQ 235
M +A VQ R I PN+GF+ QLQ
Sbjct: 141 MKYRDAFAYVQERRFCINPNAGFVHQLQ 168
>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 62.8 bits (151), Expect = 3e-10
Identities = 52/148 (35%), Positives = 76/148 (51%), Gaps = 16/148 (10%)
Query: 96 IDEVWPSLFLGDAYAARDKSKLIQL---GITHVV----NAAAGKFQVDTGAKFYRGMSLE 148
+ E+ P LFLG Y++ KSKL L GITH++ N A + + F
Sbjct: 29 MQEILPGLFLGP-YSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLF------R 81
Query: 149 YYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICEN 208
Y ++ DNP ++ +F +I +L + G+VLVH G+SRSA V+A++M
Sbjct: 82 YLVLDIADNPVENIIRFFPMTKEFIDGSLQMG-GKVLVHGNAGISRSAAFVIAYIMETFG 140
Query: 209 MTLVEAIQTVQAHR-NICPNSGFLRQLQ 235
M +A VQ R I PN+GF+ QLQ
Sbjct: 141 MKYRDAFAYVQERRFCINPNAGFVHQLQ 168
>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
Length = 176
Score = 62.4 bits (150), Expect = 4e-10
Identities = 49/144 (34%), Positives = 71/144 (49%), Gaps = 9/144 (6%)
Query: 99 VWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNP 158
V PSLFLG A AA + +L + G+T VN + + G R + + D+P
Sbjct: 22 VAPSLFLGSARAAGAEEQLARAGVTLCVNVS----RQQPGP---RAPGVAELRVPVFDDP 74
Query: 159 FFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTV 218
DL + P + AA+ G LV+C G SRSA + A+LM ++L +A Q V
Sbjct: 75 AEDLLAHLEPTCAAMEAAVRAG-GACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMV 133
Query: 219 QAHRNIC-PNSGFLRQLQVLDNRL 241
++ R + PN GF QLQ + L
Sbjct: 134 KSARPVAEPNPGFWSQLQKYEEAL 157
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 60.8 bits (146), Expect = 1e-09
Identities = 47/146 (32%), Positives = 72/146 (49%), Gaps = 7/146 (4%)
Query: 98 EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 157
++ P L+LG A + + L + GI +++N + F G Y I D+
Sbjct: 247 QILPYLYLGCAKDSTNLDVLGKYGIKYILNVTP-----NLPNAFEHGGEFTYKQIPISDH 301
Query: 158 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 217
+LS +F +I A S G VLVHC G+SRS T+ +A+LM N++L +A
Sbjct: 302 WSQNLSQFFPEAISFIDEARSKKCG-VLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDF 360
Query: 218 VQAHR-NICPNSGFLRQLQVLDNRLG 242
V+ + NI PN F+ QL + LG
Sbjct: 361 VKRKKSNISPNFNFMGQLLDFERTLG 386
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 60.5 bits (145), Expect = 1e-09
Identities = 49/155 (31%), Positives = 78/155 (50%), Gaps = 20/155 (12%)
Query: 99 VWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN- 157
+ P+L+LG +K + Q GI +V+NA+ +T K + + +D+
Sbjct: 162 ILPNLYLGCQRDVLNKELMQQNGIGYVLNAS------NTCPKPDFIPESHFLRVPVNDSF 215
Query: 158 -----PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLV 212
P+ D SV F+ A+ G VLVHC G+SRSAT+ +A++M +M+L
Sbjct: 216 CEKILPWLDKSVDFIEKAK-------ASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLD 268
Query: 213 EAIQTVQAHR-NICPNSGFLRQLQVLDNRLGRETG 246
EA + V+ R I PN FL QL + ++ +TG
Sbjct: 269 EAYRFVKEKRPTISPNFNFLGQLLDYEKKIKNQTG 303
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 60.1 bits (144), Expect = 2e-09
Identities = 43/139 (30%), Positives = 69/139 (49%), Gaps = 9/139 (6%)
Query: 98 EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 157
+++ +FLG + A + L G+ +++N ++D F+ G+ EY+ I D
Sbjct: 310 QIFEHVFLGSEWNASNLEDLQNRGVRYILNVTR---EIDN---FFPGV-FEYHNIRVYDE 362
Query: 158 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 217
DL Y+ ++I A + LVHC MGVSRSA+ V+A+ M L A
Sbjct: 363 EATDLLAYWNDTYKFISKAKK-HGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDY 421
Query: 218 VQAHRNIC-PNSGFLRQLQ 235
V+ R + PN F+RQL+
Sbjct: 422 VKERRTVTKPNPSFMRQLE 440
>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
Length = 381
Score = 58.9 bits (141), Expect = 4e-09
Identities = 45/146 (30%), Positives = 71/146 (48%), Gaps = 7/146 (4%)
Query: 98 EVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDN 157
E+ P L+LG A + + L + GI +++N + F +Y I D+
Sbjct: 209 EILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNL-----FENAGEFKYKQIPISDH 263
Query: 158 PFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQT 217
+LS +F +I A G VLVHC G+SRS T+ +A+LM N+++ +A
Sbjct: 264 WSQNLSQFFPEAISFIDEARGKNCG-VLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDI 322
Query: 218 VQAHR-NICPNSGFLRQLQVLDNRLG 242
V+ + NI PN F+ QL + LG
Sbjct: 323 VKMKKSNISPNFNFMGQLLDFERTLG 348
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 58.5 bits (140), Expect = 5e-09
Identities = 40/143 (27%), Positives = 68/143 (47%), Gaps = 10/143 (6%)
Query: 94 NHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIE 153
N + +V P L+LG+ A+D +L + ITH+++ + + Y I
Sbjct: 3 NGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLL--------QDITYLRIP 54
Query: 154 ADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVE 213
D P + +F +I + G LVHC G+SRS T+V A++M + +
Sbjct: 55 VADTPEVPIKKHFKECINFIHCC-RLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRD 113
Query: 214 AIQTVQAHRNIC-PNSGFLRQLQ 235
++ ++A R I PN GF +QL+
Sbjct: 114 VLEAIKATRPIANPNPGFRQQLE 136
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,882,020
Number of Sequences: 37866
Number of extensions: 352703
Number of successful extensions: 769
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 668
Number of HSP's gapped (non-prelim): 85
length of query: 248
length of database: 18,247,518
effective HSP length: 100
effective length of query: 148
effective length of database: 14,460,918
effective search space: 2140215864
effective search space used: 2140215864
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.