Search of human proteins with 56090539

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56090539 dysferlin-interacting protein 1 [Homo sapiens]
         (154 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56090539 dysferlin-interacting protein 1 [Homo sapiens]            314   2e-86
gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo ...   100   6e-22
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni...    96   2e-20
gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit...    96   2e-20
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun...    89   1e-18
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit...    89   1e-18
gi|28626517 protein phosphatase 1 regulatory inhibitor subunit 1...    80   5e-16
gi|14249672 protein phosphatase 1, regulatory (inhibitor) subuni...    77   8e-15
gi|51972284 NOTCH-regulated ankyrin repeat protein [Homo sapiens]      72   1e-13
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]         70   9e-13
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]         70   9e-13
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun...    65   2e-11
gi|239754054 PREDICTED: ankyrin repeat domain 31 [Homo sapiens]        65   3e-11
gi|239748581 PREDICTED: ankyrin repeat domain 31 [Homo sapiens]        65   3e-11
gi|239742600 PREDICTED: ankyrin repeat domain 31 [Homo sapiens]        65   3e-11
gi|4506217 proteasome 26S non-ATPase subunit 10 isoform 1 [Homo ...    64   7e-11
gi|28605137 proteasome 26S non-ATPase subunit 10 isform 2 [Homo ...    64   7e-11
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    64   7e-11
gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Hom...    63   1e-10
gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo ...    63   1e-10
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]                        63   1e-10
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]                         63   1e-10
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         63   1e-10
gi|68131557 ankyrin repeat domain 28 [Homo sapiens]                    62   2e-10
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]                        62   2e-10
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]                         62   2e-10
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]                         62   2e-10
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]                         62   2e-10
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]                         62   2e-10
gi|7705748 TNNI3 interacting kinase isoform b [Homo sapiens]           62   2e-10

>gi|56090539 dysferlin-interacting protein 1 [Homo sapiens]
          Length = 154

 Score =  314 bits (805), Expect = 2e-86
 Identities = 154/154 (100%), Positives = 154/154 (100%)

Query: 1   MPSRTARYARYSPRQRRRRMLADRSVRFPNDVLFLDHIRQGDLEQVGRFIRTRKVSLATI 60
           MPSRTARYARYSPRQRRRRMLADRSVRFPNDVLFLDHIRQGDLEQVGRFIRTRKVSLATI
Sbjct: 1   MPSRTARYARYSPRQRRRRMLADRSVRFPNDVLFLDHIRQGDLEQVGRFIRTRKVSLATI 60

Query: 61  HPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLG 120
           HPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLG
Sbjct: 61  HPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLG 120

Query: 121 ADRDATNDDGDLPSDLIDPDYKELVELFKGTTMD 154
           ADRDATNDDGDLPSDLIDPDYKELVELFKGTTMD
Sbjct: 121 ADRDATNDDGDLPSDLIDPDYKELVELFKGTTMD 154


>gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo
           sapiens]
          Length = 782

 Score =  100 bits (248), Expect = 6e-22
 Identities = 60/151 (39%), Positives = 80/151 (52%), Gaps = 21/151 (13%)

Query: 9   ARYSPRQRRRRMLADRSVRFPNDVLFLDHIRQGDLEQVGRFIRTR--------------- 53
           A   P +RR R     +VRF     FL     GDL++    +R                 
Sbjct: 35  AEPGPGERRAR-----TVRFERAAEFLAACAGGDLDEARLMLRAADPGPGAELDPAAPPP 89

Query: 54  -KVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDI 112
            +  L + +  G++ALH+A +  NLE V+ LV+ GA ++Q D  GWTPLH+A S GY DI
Sbjct: 90  ARAVLDSTNADGISALHQACIDENLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDI 149

Query: 113 ARYLISLGADRDATNDDGDLPSDLIDPDYKE 143
           ARYL+S GA+  A N DGDLP DL + D  E
Sbjct: 150 ARYLLSHGANIAAVNSDGDLPLDLAESDAME 180



 Score = 63.2 bits (152), Expect = 9e-11
 Identities = 35/87 (40%), Positives = 45/87 (51%), Gaps = 1/87 (1%)

Query: 61  HP-SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISL 119
           HP +G +ALH A   G +E ++LL++ G D   RD  GWTPLH A   G  D  R L   
Sbjct: 223 HPRTGASALHVAAAKGYIEVMRLLLQAGYDPELRDGDGWTPLHAAAHWGVEDACRLLAEH 282

Query: 120 GADRDATNDDGDLPSDLIDPDYKELVE 146
           G   D+    G  P DL D +   L+E
Sbjct: 283 GGGMDSLTHAGQRPCDLADEEVLSLLE 309


>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
           12B isoform b [Homo sapiens]
          Length = 998

 Score = 95.5 bits (236), Expect = 2e-20
 Identities = 56/140 (40%), Positives = 83/140 (59%), Gaps = 8/140 (5%)

Query: 13  PRQRR---RRMLADRS---VRFPNDVLFLDHIRQGDLEQVGRFIRTRKVSLATIHPSGLA 66
           P +RR   R+ L  R    VRF +  +FL     GD ++V + +  R   + T++  GL 
Sbjct: 35  PAERRGAGRQPLTRRGSPRVRFEDGAVFLAACSSGDTDEVRKLL-ARGADINTVNVDGLT 93

Query: 67  ALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDAT 126
           ALH+A +  NL+ VK LV+  A+++Q+D  GWTPLH A S GY +IA Y I+ GA     
Sbjct: 94  ALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIV 153

Query: 127 NDDGDLPSDLI-DPDYKELV 145
           N +G++PSDL  +P  K+L+
Sbjct: 154 NSEGEVPSDLAEEPAMKDLL 173



 Score = 57.8 bits (138), Expect = 4e-09
 Identities = 33/107 (30%), Positives = 51/107 (47%)

Query: 43  LEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLH 102
           L+   +++ + K+       SG  ALH A   G  E ++LL++ G +++ +D  GWTPLH
Sbjct: 196 LQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLH 255

Query: 103 IACSDGYPDIARYLISLGADRDATNDDGDLPSDLIDPDYKELVELFK 149
            A   G  +    L     D D  N  G  P D+ D    E +EL +
Sbjct: 256 AAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLELLQ 302


>gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit
           12B isoform a [Homo sapiens]
          Length = 982

 Score = 95.5 bits (236), Expect = 2e-20
 Identities = 56/140 (40%), Positives = 83/140 (59%), Gaps = 8/140 (5%)

Query: 13  PRQRR---RRMLADRS---VRFPNDVLFLDHIRQGDLEQVGRFIRTRKVSLATIHPSGLA 66
           P +RR   R+ L  R    VRF +  +FL     GD ++V + +  R   + T++  GL 
Sbjct: 35  PAERRGAGRQPLTRRGSPRVRFEDGAVFLAACSSGDTDEVRKLL-ARGADINTVNVDGLT 93

Query: 67  ALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDAT 126
           ALH+A +  NL+ VK LV+  A+++Q+D  GWTPLH A S GY +IA Y I+ GA     
Sbjct: 94  ALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIV 153

Query: 127 NDDGDLPSDLI-DPDYKELV 145
           N +G++PSDL  +P  K+L+
Sbjct: 154 NSEGEVPSDLAEEPAMKDLL 173



 Score = 57.8 bits (138), Expect = 4e-09
 Identities = 33/107 (30%), Positives = 51/107 (47%)

Query: 43  LEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLH 102
           L+   +++ + K+       SG  ALH A   G  E ++LL++ G +++ +D  GWTPLH
Sbjct: 196 LQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLH 255

Query: 103 IACSDGYPDIARYLISLGADRDATNDDGDLPSDLIDPDYKELVELFK 149
            A   G  +    L     D D  N  G  P D+ D    E +EL +
Sbjct: 256 AAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLELLQ 302


>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
           12A isoform a [Homo sapiens]
          Length = 1030

 Score = 89.0 bits (219), Expect = 1e-18
 Identities = 47/118 (39%), Positives = 68/118 (57%), Gaps = 1/118 (0%)

Query: 26  VRFPNDVLFLDHIRQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVK 85
           V+F +  +FL     GD ++V + +  R   +   +  GL ALH+A +  N++ VK LV+
Sbjct: 36  VKFDDGAVFLAACSSGDTDEVLKLLH-RGADINYANVDGLTALHQACIDDNVDMVKFLVE 94

Query: 86  YGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDGDLPSDLIDPDYKE 143
            GA+I+Q D  GW PLH A S GY DIA +LI  GA   A N +GD P D+ + +  E
Sbjct: 95  NGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAME 152



 Score = 56.6 bits (135), Expect = 8e-09
 Identities = 30/78 (38%), Positives = 40/78 (51%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           SG  ALH A   G  E +KLL++ G D++ +D  GWTPLH A   G  +  R L+    D
Sbjct: 198 SGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCD 257

Query: 123 RDATNDDGDLPSDLIDPD 140
            +  N  G    D+ D D
Sbjct: 258 MEMVNKVGQTAFDVADED 275



 Score = 32.0 bits (71), Expect = 0.22
 Identities = 14/39 (35%), Positives = 23/39 (58%)

Query: 95  EAGWTPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           ++G T LH+A + GY ++ + LI  G D +  + DG  P
Sbjct: 197 KSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTP 235


>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit
           12A isoform a [Homo sapiens]
          Length = 1030

 Score = 89.0 bits (219), Expect = 1e-18
 Identities = 47/118 (39%), Positives = 68/118 (57%), Gaps = 1/118 (0%)

Query: 26  VRFPNDVLFLDHIRQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVK 85
           V+F +  +FL     GD ++V + +  R   +   +  GL ALH+A +  N++ VK LV+
Sbjct: 36  VKFDDGAVFLAACSSGDTDEVLKLLH-RGADINYANVDGLTALHQACIDDNVDMVKFLVE 94

Query: 86  YGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDGDLPSDLIDPDYKE 143
            GA+I+Q D  GW PLH A S GY DIA +LI  GA   A N +GD P D+ + +  E
Sbjct: 95  NGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAME 152



 Score = 56.6 bits (135), Expect = 8e-09
 Identities = 30/78 (38%), Positives = 40/78 (51%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           SG  ALH A   G  E +KLL++ G D++ +D  GWTPLH A   G  +  R L+    D
Sbjct: 198 SGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCD 257

Query: 123 RDATNDDGDLPSDLIDPD 140
            +  N  G    D+ D D
Sbjct: 258 MEMVNKVGQTAFDVADED 275



 Score = 32.0 bits (71), Expect = 0.22
 Identities = 14/39 (35%), Positives = 23/39 (58%)

Query: 95  EAGWTPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           ++G T LH+A + GY ++ + LI  G D +  + DG  P
Sbjct: 197 KSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTP 235


>gi|28626517 protein phosphatase 1 regulatory inhibitor subunit 16B
           [Homo sapiens]
          Length = 567

 Score = 80.5 bits (197), Expect = 5e-16
 Identities = 49/147 (33%), Positives = 77/147 (52%), Gaps = 7/147 (4%)

Query: 14  RQRRRRMLADR--SVRFPNDVLFLDHIRQGDLEQVGRFIRTRKVSLATIHPSGLAALHEA 71
           +  R+R    R   V F   V  L+   + D E+V  F++  KVS    +  GL ALH+ 
Sbjct: 50  KHERKRSTGGRRKKVSFEASVALLEASLRNDAEEVRYFLKN-KVSPDLCNEDGLTALHQC 108

Query: 72  VLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDGD 131
            +    E VKLL+ +GA+++ +D   WTPLH A + G+ ++ + L+  GAD  A N DG+
Sbjct: 109 CIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGN 168

Query: 132 LPSDLIDP----DYKELVELFKGTTMD 154
           +P DL +     D  E    ++G T +
Sbjct: 169 MPYDLCEDEPTLDVIETCMAYQGITQE 195



 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 27/81 (33%), Positives = 39/81 (48%)

Query: 60  IHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISL 119
           I   G   LH A  +G L   +LL+ +G  +  +D  GW PLH A   G   +A  L+S 
Sbjct: 225 IDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSH 284

Query: 120 GADRDATNDDGDLPSDLIDPD 140
           GA   A     ++P DL + +
Sbjct: 285 GASLSARTSMDEMPIDLCEEE 305



 Score = 30.0 bits (66), Expect = 0.82
 Identities = 17/51 (33%), Positives = 25/51 (49%)

Query: 80  VKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDG 130
           +  ++  G D+   D  G T LHIA ++GY   A  L+  G   D  + DG
Sbjct: 212 IHCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDG 262


>gi|14249672 protein phosphatase 1, regulatory (inhibitor) subunit
           16A [Homo sapiens]
          Length = 528

 Score = 76.6 bits (187), Expect = 8e-15
 Identities = 52/150 (34%), Positives = 78/150 (52%), Gaps = 9/150 (6%)

Query: 13  PRQRRRRMLAD----RSVRFPNDVLFLDHIRQGDLEQVGRFIRTRKVSLATIHPSGLAAL 68
           P +R R+  A     + V FP  V+ L+   + DLE+V +F+ +  VS    +  GL AL
Sbjct: 50  PGERPRKEAASQGLLKQVLFPPSVVLLEAAARNDLEEVRQFLGSG-VSPDLANEDGLTAL 108

Query: 69  HEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATND 128
           H+  +    E V+ L++ GA+I+  D   WTPLH A + G+  +   LI+ GA+  A N 
Sbjct: 109 HQCCIDDFREMVQQLLEAGANINACDSECWTPLHAAATCGHLHLVELLIASGANLLAVNT 168

Query: 129 DGDLPSDLIDP----DYKELVELFKGTTMD 154
           DG++P DL D     D  E     +G T D
Sbjct: 169 DGNMPYDLCDDEQTLDCLETAMADRGITQD 198



 Score = 48.5 bits (114), Expect = 2e-06
 Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 3/90 (3%)

Query: 50  IRTRKVSLATIHPS---GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACS 106
           IR+R  + A +H     G   LH A  +G  E   LL+++ A +  +D+ GW PLH A  
Sbjct: 215 IRSRLQAGADLHAPLDHGATLLHVAAANGFSEAAALLLEHRASLSAKDQDGWEPLHAAAY 274

Query: 107 DGYPDIARYLISLGADRDATNDDGDLPSDL 136
            G   +   L++ GAD +A +   + P D+
Sbjct: 275 WGQVPLVELLVAHGADLNAKSLMDETPLDV 304



 Score = 35.0 bits (79), Expect = 0.025
 Identities = 17/54 (31%), Positives = 31/54 (57%)

Query: 77  LECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDG 130
           L+ ++  ++ GAD+H   + G T LH+A ++G+ + A  L+   A   A + DG
Sbjct: 212 LDDIRSRLQAGADLHAPLDHGATLLHVAAANGFSEAAALLLEHRASLSAKDQDG 265


>gi|51972284 NOTCH-regulated ankyrin repeat protein [Homo sapiens]
          Length = 114

 Score = 72.4 bits (176), Expect = 1e-13
 Identities = 35/89 (39%), Positives = 57/89 (64%), Gaps = 3/89 (3%)

Query: 33  LFLDHIRQGDLEQVGRFIRTR---KVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGAD 89
           +F + +R+G+ +++   ++     + ++ +  P G  ALH++V+ GNLE VKLLVK+GAD
Sbjct: 17  IFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGAD 76

Query: 90  IHQRDEAGWTPLHIACSDGYPDIARYLIS 118
           I   +  GW+ LHIA   G+ DI  YLI+
Sbjct: 77  IRLANRDGWSALHIAAFGGHQDIVLYLIT 105



 Score = 30.0 bits (66), Expect = 0.82
 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 4/73 (5%)

Query: 62  PSGLAALHEAVLSGNLECVKLLVKYGAD----IHQRDEAGWTPLHIACSDGYPDIARYLI 117
           P       EAV  GN + ++ L++   +    ++     G T LH +  DG  ++ + L+
Sbjct: 12  PQTQRIFQEAVRKGNTQELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLV 71

Query: 118 SLGADRDATNDDG 130
             GAD    N DG
Sbjct: 72  KFGADIRLANRDG 84


>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
          Length = 2039

 Score = 69.7 bits (169), Expect = 9e-13
 Identities = 35/85 (41%), Positives = 54/85 (63%), Gaps = 1/85 (1%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G   LH A + G+++ VK L+  GA+++ +D AGWTPLH AC+ GY D+A+ LI+ GAD 
Sbjct: 162 GETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADV 221

Query: 124 DATNDDGDLP-SDLIDPDYKELVEL 147
           +    D D P  D     ++++V+L
Sbjct: 222 NTQGLDDDTPLHDSASSGHRDIVKL 246



 Score = 51.6 bits (122), Expect = 3e-07
 Identities = 32/106 (30%), Positives = 55/106 (51%), Gaps = 1/106 (0%)

Query: 40  QGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWT 99
           +GD++QV   I +   ++     +G   LHEA   G  +  K+L+  GAD++ +     T
Sbjct: 172 RGDVKQVKELI-SLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDT 230

Query: 100 PLHIACSDGYPDIARYLISLGADRDATNDDGDLPSDLIDPDYKELV 145
           PLH + S G+ DI + L+  G +    N  G+ P D+ + +  EL+
Sbjct: 231 PLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELL 276



 Score = 33.5 bits (75), Expect = 0.074
 Identities = 20/80 (25%), Positives = 42/80 (52%), Gaps = 3/80 (3%)

Query: 58  ATIHPSGL---AALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIAR 114
           A ++  GL     LH++  SG+ + VKLL+++G +  Q ++ G  P+ +A ++    + +
Sbjct: 219 ADVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLK 278

Query: 115 YLISLGADRDATNDDGDLPS 134
             + L  D ++  D  +  S
Sbjct: 279 REVPLSDDDESYTDSEEAQS 298


>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
          Length = 2062

 Score = 69.7 bits (169), Expect = 9e-13
 Identities = 35/85 (41%), Positives = 54/85 (63%), Gaps = 1/85 (1%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G   LH A + G+++ VK L+  GA+++ +D AGWTPLH AC+ GY D+A+ LI+ GAD 
Sbjct: 185 GETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADV 244

Query: 124 DATNDDGDLP-SDLIDPDYKELVEL 147
           +    D D P  D     ++++V+L
Sbjct: 245 NTQGLDDDTPLHDSASSGHRDIVKL 269



 Score = 51.6 bits (122), Expect = 3e-07
 Identities = 32/106 (30%), Positives = 55/106 (51%), Gaps = 1/106 (0%)

Query: 40  QGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWT 99
           +GD++QV   I +   ++     +G   LHEA   G  +  K+L+  GAD++ +     T
Sbjct: 195 RGDVKQVKELI-SLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDT 253

Query: 100 PLHIACSDGYPDIARYLISLGADRDATNDDGDLPSDLIDPDYKELV 145
           PLH + S G+ DI + L+  G +    N  G+ P D+ + +  EL+
Sbjct: 254 PLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELL 299



 Score = 33.5 bits (75), Expect = 0.074
 Identities = 20/80 (25%), Positives = 42/80 (52%), Gaps = 3/80 (3%)

Query: 58  ATIHPSGL---AALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIAR 114
           A ++  GL     LH++  SG+ + VKLL+++G +  Q ++ G  P+ +A ++    + +
Sbjct: 242 ADVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLK 301

Query: 115 YLISLGADRDATNDDGDLPS 134
             + L  D ++  D  +  S
Sbjct: 302 REVPLSDDDESYTDSEEAQS 321


>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
           12A isoform b [Homo sapiens]
          Length = 943

 Score = 65.1 bits (157), Expect = 2e-11
 Identities = 32/64 (50%), Positives = 40/64 (62%)

Query: 80  VKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDGDLPSDLIDP 139
           VK LV+ GA+I+Q D  GW PLH A S GY DIA +LI  GA   A N +GD P D+ + 
Sbjct: 2   VKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEE 61

Query: 140 DYKE 143
           +  E
Sbjct: 62  EAME 65



 Score = 56.6 bits (135), Expect = 8e-09
 Identities = 30/78 (38%), Positives = 40/78 (51%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           SG  ALH A   G  E +KLL++ G D++ +D  GWTPLH A   G  +  R L+    D
Sbjct: 111 SGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCD 170

Query: 123 RDATNDDGDLPSDLIDPD 140
            +  N  G    D+ D D
Sbjct: 171 MEMVNKVGQTAFDVADED 188



 Score = 32.0 bits (71), Expect = 0.22
 Identities = 14/39 (35%), Positives = 23/39 (58%)

Query: 95  EAGWTPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           ++G T LH+A + GY ++ + LI  G D +  + DG  P
Sbjct: 110 KSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTP 148



 Score = 27.7 bits (60), Expect = 4.1
 Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 1/67 (1%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLIS-LGAD 122
           G   LH A   G L+  + L+  GA +   +  G TPL IA  +   ++ +  ++  G D
Sbjct: 19  GWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVD 78

Query: 123 RDATNDD 129
            +A   +
Sbjct: 79  IEAARKE 85


>gi|239754054 PREDICTED: ankyrin repeat domain 31 [Homo sapiens]
          Length = 1873

 Score = 64.7 bits (156), Expect = 3e-11
 Identities = 34/70 (48%), Positives = 43/70 (61%)

Query: 64   GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
            G + LH AV  GNL  VK L++ GAD++  D AGWTPLH A ++G  DI   L+  GA  
Sbjct: 1155 GESQLHLAVRRGNLPLVKALIESGADVNLNDNAGWTPLHEASNEGSIDIIVELLKAGAKV 1214

Query: 124  DATNDDGDLP 133
            +  N DG LP
Sbjct: 1215 NCENIDGILP 1224



 Score = 46.6 bits (109), Expect = 8e-06
 Identities = 28/73 (38%), Positives = 38/73 (52%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G  ALHEA + G       L+K GAD++ +     TPLH A  +G+  +A  L+  GAD
Sbjct: 521 AGWTALHEASVGGFYRTASELLKGGADVNIKGLYQITPLHDAVMNGHYKVAELLLLNGAD 580

Query: 123 RDATNDDGDLPSD 135
               NDDG    D
Sbjct: 581 PLFRNDDGKCALD 593



 Score = 39.3 bits (90), Expect = 0.001
 Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 50  IRTRKVSLATIHPSGLAA---LHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACS 106
           ++  K+SL +I+   +     +++A L  + + V   +K G +++Q   AGWT LH A  
Sbjct: 472 MKVNKISLHSINRRNIFGENLVYKAALHDDADLVHHCIKKGGNVNQPSYAGWTALHEASV 531

Query: 107 DGYPDIARYLISLGAD 122
            G+   A  L+  GAD
Sbjct: 532 GGFYRTASELLKGGAD 547



 Score = 37.4 bits (85), Expect = 0.005
 Identities = 30/112 (26%), Positives = 54/112 (48%), Gaps = 3/112 (2%)

Query: 38   IRQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAG 97
            +R+G+L  V   I +    +     +G   LHEA   G+++ +  L+K GA ++  +  G
Sbjct: 1163 VRRGNLPLVKALIESG-ADVNLNDNAGWTPLHEASNEGSIDIIVELLKAGAKVNCENIDG 1221

Query: 98   WTPLHIACSDGYPDIARYLISLGADRDATNDDGDLPSDLIDPDYKELVELFK 149
              PLH A ++ +   A  L+  GA  +    D    S L + D +++ EL +
Sbjct: 1222 ILPLHDAVANNHLKAAEILLQNGA--NPNQKDQKQKSALDEADDEKMKELLR 1271


>gi|239748581 PREDICTED: ankyrin repeat domain 31 [Homo sapiens]
          Length = 1873

 Score = 64.7 bits (156), Expect = 3e-11
 Identities = 34/70 (48%), Positives = 43/70 (61%)

Query: 64   GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
            G + LH AV  GNL  VK L++ GAD++  D AGWTPLH A ++G  DI   L+  GA  
Sbjct: 1155 GESQLHLAVRRGNLPLVKALIESGADVNLNDNAGWTPLHEASNEGSIDIIVELLKAGAKV 1214

Query: 124  DATNDDGDLP 133
            +  N DG LP
Sbjct: 1215 NCENIDGILP 1224



 Score = 46.6 bits (109), Expect = 8e-06
 Identities = 28/73 (38%), Positives = 38/73 (52%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G  ALHEA + G       L+K GAD++ +     TPLH A  +G+  +A  L+  GAD
Sbjct: 521 AGWTALHEASVGGFYRTASELLKGGADVNIKGLYQITPLHDAVMNGHYKVAELLLLNGAD 580

Query: 123 RDATNDDGDLPSD 135
               NDDG    D
Sbjct: 581 PLFRNDDGKCALD 593



 Score = 39.3 bits (90), Expect = 0.001
 Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 50  IRTRKVSLATIHPSGLAA---LHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACS 106
           ++  K+SL +I+   +     +++A L  + + V   +K G +++Q   AGWT LH A  
Sbjct: 472 MKVNKISLHSINRRNIFGENLVYKAALHDDADLVHHCIKKGGNVNQPSYAGWTALHEASV 531

Query: 107 DGYPDIARYLISLGAD 122
            G+   A  L+  GAD
Sbjct: 532 GGFYRTASELLKGGAD 547



 Score = 37.4 bits (85), Expect = 0.005
 Identities = 30/112 (26%), Positives = 54/112 (48%), Gaps = 3/112 (2%)

Query: 38   IRQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAG 97
            +R+G+L  V   I +    +     +G   LHEA   G+++ +  L+K GA ++  +  G
Sbjct: 1163 VRRGNLPLVKALIESG-ADVNLNDNAGWTPLHEASNEGSIDIIVELLKAGAKVNCENIDG 1221

Query: 98   WTPLHIACSDGYPDIARYLISLGADRDATNDDGDLPSDLIDPDYKELVELFK 149
              PLH A ++ +   A  L+  GA  +    D    S L + D +++ EL +
Sbjct: 1222 ILPLHDAVANNHLKAAEILLQNGA--NPNQKDQKQKSALDEADDEKMKELLR 1271


>gi|239742600 PREDICTED: ankyrin repeat domain 31 [Homo sapiens]
          Length = 1873

 Score = 64.7 bits (156), Expect = 3e-11
 Identities = 34/70 (48%), Positives = 43/70 (61%)

Query: 64   GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
            G + LH AV  GNL  VK L++ GAD++  D AGWTPLH A ++G  DI   L+  GA  
Sbjct: 1155 GESQLHLAVRRGNLPLVKALIESGADVNLNDNAGWTPLHEASNEGSIDIIVELLKAGAKV 1214

Query: 124  DATNDDGDLP 133
            +  N DG LP
Sbjct: 1215 NCENIDGILP 1224



 Score = 46.6 bits (109), Expect = 8e-06
 Identities = 28/73 (38%), Positives = 38/73 (52%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G  ALHEA + G       L+K GAD++ +     TPLH A  +G+  +A  L+  GAD
Sbjct: 521 AGWTALHEASVGGFYRTASELLKGGADVNIKGLYQITPLHDAVMNGHYKVAELLLLNGAD 580

Query: 123 RDATNDDGDLPSD 135
               NDDG    D
Sbjct: 581 PLFRNDDGKCALD 593



 Score = 39.3 bits (90), Expect = 0.001
 Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 50  IRTRKVSLATIHPSGLAA---LHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACS 106
           ++  K+SL +I+   +     +++A L  + + V   +K G +++Q   AGWT LH A  
Sbjct: 472 MKVNKISLHSINRRNIFGENLVYKAALHDDADLVHHCIKKGGNVNQPSYAGWTALHEASV 531

Query: 107 DGYPDIARYLISLGAD 122
            G+   A  L+  GAD
Sbjct: 532 GGFYRTASELLKGGAD 547



 Score = 37.4 bits (85), Expect = 0.005
 Identities = 30/112 (26%), Positives = 54/112 (48%), Gaps = 3/112 (2%)

Query: 38   IRQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAG 97
            +R+G+L  V   I +    +     +G   LHEA   G+++ +  L+K GA ++  +  G
Sbjct: 1163 VRRGNLPLVKALIESG-ADVNLNDNAGWTPLHEASNEGSIDIIVELLKAGAKVNCENIDG 1221

Query: 98   WTPLHIACSDGYPDIARYLISLGADRDATNDDGDLPSDLIDPDYKELVELFK 149
              PLH A ++ +   A  L+  GA  +    D    S L + D +++ EL +
Sbjct: 1222 ILPLHDAVANNHLKAAEILLQNGA--NPNQKDQKQKSALDEADDEKMKELLR 1271


>gi|4506217 proteasome 26S non-ATPase subunit 10 isoform 1 [Homo
           sapiens]
          Length = 226

 Score = 63.5 bits (153), Expect = 7e-11
 Identities = 33/93 (35%), Positives = 50/93 (53%)

Query: 41  GDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTP 100
           G LE++   I   K            ALH A  +G+ E V+ L++ G  ++ +D+AGW+P
Sbjct: 17  GKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSP 76

Query: 101 LHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           LHIA S G  +I + L+  GA  +A N +G  P
Sbjct: 77  LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTP 109



 Score = 48.1 bits (113), Expect = 3e-06
 Identities = 24/67 (35%), Positives = 37/67 (55%)

Query: 67  ALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDAT 126
           A+H A   GNL+ + +L+ Y A  + +D  G TPLH+AC +   + A+ L+S GA     
Sbjct: 142 AMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIE 201

Query: 127 NDDGDLP 133
           N +   P
Sbjct: 202 NKEEKTP 208



 Score = 43.1 bits (100), Expect = 9e-05
 Identities = 25/63 (39%), Positives = 36/63 (57%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G + LH A  +G  E VK L+  GA ++  ++ G TPLH A S    +IA  L+  GA+
Sbjct: 72  AGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGAN 131

Query: 123 RDA 125
            DA
Sbjct: 132 PDA 134



 Score = 26.9 bits (58), Expect = 6.9
 Identities = 16/41 (39%), Positives = 21/41 (51%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIA 104
           G   LH A     +E  KLLV  GA I+  ++   TPL +A
Sbjct: 172 GNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212


>gi|28605137 proteasome 26S non-ATPase subunit 10 isform 2 [Homo
           sapiens]
          Length = 151

 Score = 63.5 bits (153), Expect = 7e-11
 Identities = 33/93 (35%), Positives = 50/93 (53%)

Query: 41  GDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTP 100
           G LE++   I   K            ALH A  +G+ E V+ L++ G  ++ +D+AGW+P
Sbjct: 17  GKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSP 76

Query: 101 LHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           LHIA S G  +I + L+  GA  +A N +G  P
Sbjct: 77  LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTP 109



 Score = 43.1 bits (100), Expect = 9e-05
 Identities = 25/63 (39%), Positives = 36/63 (57%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G + LH A  +G  E VK L+  GA ++  ++ G TPLH A S    +IA  L+  GA+
Sbjct: 72  AGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGAN 131

Query: 123 RDA 125
            DA
Sbjct: 132 PDA 134


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 63.5 bits (153), Expect = 7e-11
 Identities = 29/70 (41%), Positives = 43/70 (61%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G   LH A + G+   +K L+  GAD++ +D AGWT LH AC+ GY D+A+ L++ GA+ 
Sbjct: 168 GETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEV 227

Query: 124 DATNDDGDLP 133
           +    D D P
Sbjct: 228 NTKGLDDDTP 237



 Score = 44.7 bits (104), Expect = 3e-05
 Identities = 26/89 (29%), Positives = 45/89 (50%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G  ALHEA   G  +  K L+  GA+++ +     TPLH A ++G+  + + L+  G +
Sbjct: 200 AGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGN 259

Query: 123 RDATNDDGDLPSDLIDPDYKELVELFKGT 151
              +N  G+ P  + +      + L KGT
Sbjct: 260 PQQSNRKGETPLKVANSPTMVNLLLGKGT 288


>gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Homo
            sapiens]
          Length = 1134

 Score = 62.8 bits (151), Expect = 1e-10
 Identities = 36/97 (37%), Positives = 53/97 (54%), Gaps = 3/97 (3%)

Query: 26   VRFPNDVLFLDHIRQGDLEQVGRFI-RTRKVSLATIHPSGLAALHEAVLSGNLECVKLLV 84
            V+F    L LD   +G+ + V R I      SL   +  G+ ALH AV +G+ E VK LV
Sbjct: 928  VKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLP--NDEGITALHNAVCAGHTEIVKFLV 985

Query: 85   KYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGA 121
            ++G +++  D  GWTPLH A S     + ++L+  GA
Sbjct: 986  QFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 1022



 Score = 37.0 bits (84), Expect = 0.007
 Identities = 20/69 (28%), Positives = 36/69 (52%)

Query: 65   LAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRD 124
            LA L ++ L G  + V+ ++    D    ++ G T LH A   G+ +I ++L+  G + +
Sbjct: 933  LALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVN 992

Query: 125  ATNDDGDLP 133
            A + DG  P
Sbjct: 993  AADSDGWTP 1001


>gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo
           sapiens]
          Length = 1005

 Score = 62.8 bits (151), Expect = 1e-10
 Identities = 36/97 (37%), Positives = 53/97 (54%), Gaps = 3/97 (3%)

Query: 26  VRFPNDVLFLDHIRQGDLEQVGRFI-RTRKVSLATIHPSGLAALHEAVLSGNLECVKLLV 84
           V+F    L LD   +G+ + V R I      SL   +  G+ ALH AV +G+ E VK LV
Sbjct: 799 VKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLP--NDEGITALHNAVCAGHTEIVKFLV 856

Query: 85  KYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGA 121
           ++G +++  D  GWTPLH A S     + ++L+  GA
Sbjct: 857 QFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893



 Score = 37.0 bits (84), Expect = 0.007
 Identities = 20/69 (28%), Positives = 36/69 (52%)

Query: 65  LAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRD 124
           LA L ++ L G  + V+ ++    D    ++ G T LH A   G+ +I ++L+  G + +
Sbjct: 804 LALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVN 863

Query: 125 ATNDDGDLP 133
           A + DG  P
Sbjct: 864 AADSDGWTP 872


>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
          Length = 1863

 Score = 62.8 bits (151), Expect = 1e-10
 Identities = 31/81 (38%), Positives = 50/81 (61%)

Query: 53  RKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDI 112
           R  S+ +    G  ALH A L+G  E VK+LVK GA+I+ + + G+TPL++A  + + D+
Sbjct: 65  RGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDV 124

Query: 113 ARYLISLGADRDATNDDGDLP 133
            +YL+  GA++    +DG  P
Sbjct: 125 VKYLLENGANQSTATEDGFTP 145



 Score = 52.8 bits (125), Expect = 1e-07
 Identities = 27/69 (39%), Positives = 39/69 (56%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A     ++ ++LLVKYGA I    E+G TP+H+A   G+ +I   L+  GA 
Sbjct: 376 NGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGAS 435

Query: 123 RDATNDDGD 131
            D TN  G+
Sbjct: 436 PDVTNIRGE 444



 Score = 48.1 bits (113), Expect = 3e-06
 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 1/98 (1%)

Query: 39  RQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGW 98
           + G L+ V + +  R+ +  +   +GL  LH A    N +   LL++ GA  H   + G+
Sbjct: 551 KYGSLD-VAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGY 609

Query: 99  TPLHIACSDGYPDIARYLISLGADRDATNDDGDLPSDL 136
           TPLHIA       IA  L++ GA+ +     G  P  L
Sbjct: 610 TPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHL 647



 Score = 47.4 bits (111), Expect = 5e-06
 Identities = 26/70 (37%), Positives = 38/70 (54%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G+  LH A   G+ + V LL+  GA+IH   ++G T LH+A  +   ++A  L   GAD+
Sbjct: 641 GVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQ 700

Query: 124 DATNDDGDLP 133
           DA    G  P
Sbjct: 701 DAHTKLGYTP 710



 Score = 47.4 bits (111), Expect = 5e-06
 Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 3/79 (3%)

Query: 58  ATIH---PSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIAR 114
           A IH    SGL +LH A     +    +L K+GAD     + G+TPL +AC  G   +  
Sbjct: 665 ANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVN 724

Query: 115 YLISLGADRDATNDDGDLP 133
           +L+  GA+ +A   +G  P
Sbjct: 725 FLLKQGANVNAKTKNGYTP 743



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 32/107 (29%), Positives = 46/107 (42%)

Query: 27  RFPNDVLFLDHIRQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKY 86
           R  N +  L    QGD  +  + +   K  +  +    L ALH A   G+    KLL+  
Sbjct: 307 RTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDK 366

Query: 87  GADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
            A+ + R   G+TPLHIAC      +   L+  GA   A  + G  P
Sbjct: 367 RANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTP 413



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 24/68 (35%), Positives = 38/68 (55%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G   L  A   GN++ V  L+K GA+++ + + G+TPLH A   G+  I   L+  GA  
Sbjct: 707 GYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKP 766

Query: 124 DATNDDGD 131
           +AT  +G+
Sbjct: 767 NATTANGN 774



 Score = 45.1 bits (105), Expect = 2e-05
 Identities = 25/71 (35%), Positives = 33/71 (46%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G+  LH A   GN   VKLL+  G  I  +   G TPLH A   G+  +   L+  GA 
Sbjct: 244 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAP 303

Query: 123 RDATNDDGDLP 133
             A   +G  P
Sbjct: 304 LLARTKNGLSP 314



 Score = 43.9 bits (102), Expect = 5e-05
 Identities = 25/71 (35%), Positives = 33/71 (46%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           SG   LH A   GN+    LL+  GA +      G TPLH+A   G  ++ + L+  G  
Sbjct: 211 SGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQ 270

Query: 123 RDATNDDGDLP 133
            DA   DG  P
Sbjct: 271 IDAKTRDGLTP 281



 Score = 43.5 bits (101), Expect = 7e-05
 Identities = 26/70 (37%), Positives = 36/70 (51%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G  ALH A  +G +E V+ L++ GA +  R     TPLHIA   G  +I + L+   A  
Sbjct: 443 GETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHP 502

Query: 124 DATNDDGDLP 133
           DA   +G  P
Sbjct: 503 DAATTNGYTP 512



 Score = 43.1 bits (100), Expect = 9e-05
 Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 2/114 (1%)

Query: 17  RRRMLADRSVRFPNDVLFLDHIRQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGN 76
           +RR  AD + +  N +  L      D ++V   +  +  S      +G   LH A     
Sbjct: 563 QRRAAADSAGK--NGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQ 620

Query: 77  LECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDG 130
           ++    L+ YGA+ +   + G TPLH+A  +G+ D+   L+  GA+   +   G
Sbjct: 621 MQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSG 674



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 27/78 (34%), Positives = 38/78 (48%)

Query: 56  SLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARY 115
           S+  I  SGL  +H A   G+L  V LL++ GA     +  G T LH+A   G  ++ R 
Sbjct: 402 SIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRC 461

Query: 116 LISLGADRDATNDDGDLP 133
           L+  GA  DA   +   P
Sbjct: 462 LLRNGALVDARAREEQTP 479



 Score = 41.2 bits (95), Expect = 4e-04
 Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 2/78 (2%)

Query: 56  SLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARY 115
           SLAT    G   LH A   G+L+  KLL++  A      + G TPLH+A       +A  
Sbjct: 536 SLAT--KKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALL 593

Query: 116 LISLGADRDATNDDGDLP 133
           L+  GA   AT  +G  P
Sbjct: 594 LLEKGASPHATAKNGYTP 611



 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 23/66 (34%), Positives = 32/66 (48%)

Query: 68  LHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATN 127
           LH A   G  E V+LL+++ A        G+TPLHI+  +G  D+A  L+  GA      
Sbjct: 480 LHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLAT 539

Query: 128 DDGDLP 133
             G  P
Sbjct: 540 KKGFTP 545



 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 21/71 (29%), Positives = 36/71 (50%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH +   G ++   +L++ GA      + G+TPLH+A   G  D+A+ L+   A 
Sbjct: 508 NGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAA 567

Query: 123 RDATNDDGDLP 133
            D+   +G  P
Sbjct: 568 ADSAGKNGLTP 578



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 21/61 (34%), Positives = 35/61 (57%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           GL  LH A  SG+ + V+LL++ GA +  R + G +PLH+A    + +  ++L+   A  
Sbjct: 278 GLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPV 337

Query: 124 D 124
           D
Sbjct: 338 D 338



 Score = 37.7 bits (86), Expect = 0.004
 Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 8/77 (10%)

Query: 65  LAALHEAVLSGNLECVKLLVK--YGADIHQR------DEAGWTPLHIACSDGYPDIARYL 116
           L ALH A    + +   LL++  + AD+  +       E+G+TPLHIA   G  ++A  L
Sbjct: 172 LPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLL 231

Query: 117 ISLGADRDATNDDGDLP 133
           ++ GA  D T  +G  P
Sbjct: 232 LNRGAAVDFTARNGITP 248



 Score = 37.7 bits (86), Expect = 0.004
 Identities = 25/90 (27%), Positives = 43/90 (47%)

Query: 44  EQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHI 103
           +QV   +  R   L     +GL+ LH A    ++ECVK L+++ A +        T LH+
Sbjct: 291 DQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHV 350

Query: 104 ACSDGYPDIARYLISLGADRDATNDDGDLP 133
           A   G+  + + L+   A+ +A   +G  P
Sbjct: 351 AAHCGHYRVTKLLLDKRANPNARALNGFTP 380



 Score = 36.6 bits (83), Expect = 0.009
 Identities = 19/66 (28%), Positives = 35/66 (53%)

Query: 66  AALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDA 125
           A+   A  +GNL+ V   +K G DI+  ++ G   LH+A  +G+  + + L+  G+  D+
Sbjct: 12  ASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDS 71

Query: 126 TNDDGD 131
               G+
Sbjct: 72  ATKKGN 77



 Score = 32.0 bits (71), Expect = 0.22
 Identities = 16/55 (29%), Positives = 28/55 (50%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLI 117
           +G   L+ A    +++ VK L++ GA+     E G+TPL +A   G+      L+
Sbjct: 108 NGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILL 162



 Score = 27.7 bits (60), Expect = 4.1
 Identities = 15/47 (31%), Positives = 24/47 (51%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGY 109
           +G   LH+A   G+   + +L+++GA  +     G T L IA   GY
Sbjct: 739 NGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGY 785


>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
          Length = 1872

 Score = 62.8 bits (151), Expect = 1e-10
 Identities = 31/81 (38%), Positives = 50/81 (61%)

Query: 53  RKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDI 112
           R  S+ +    G  ALH A L+G  E VK+LVK GA+I+ + + G+TPL++A  + + D+
Sbjct: 86  RGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDV 145

Query: 113 ARYLISLGADRDATNDDGDLP 133
            +YL+  GA++    +DG  P
Sbjct: 146 VKYLLENGANQSTATEDGFTP 166



 Score = 52.8 bits (125), Expect = 1e-07
 Identities = 27/69 (39%), Positives = 39/69 (56%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A     ++ ++LLVKYGA I    E+G TP+H+A   G+ +I   L+  GA 
Sbjct: 397 NGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGAS 456

Query: 123 RDATNDDGD 131
            D TN  G+
Sbjct: 457 PDVTNIRGE 465



 Score = 48.1 bits (113), Expect = 3e-06
 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 1/98 (1%)

Query: 39  RQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGW 98
           + G L+ V + +  R+ +  +   +GL  LH A    N +   LL++ GA  H   + G+
Sbjct: 572 KYGSLD-VAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGY 630

Query: 99  TPLHIACSDGYPDIARYLISLGADRDATNDDGDLPSDL 136
           TPLHIA       IA  L++ GA+ +     G  P  L
Sbjct: 631 TPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHL 668



 Score = 47.4 bits (111), Expect = 5e-06
 Identities = 26/70 (37%), Positives = 38/70 (54%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G+  LH A   G+ + V LL+  GA+IH   ++G T LH+A  +   ++A  L   GAD+
Sbjct: 662 GVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQ 721

Query: 124 DATNDDGDLP 133
           DA    G  P
Sbjct: 722 DAHTKLGYTP 731



 Score = 47.4 bits (111), Expect = 5e-06
 Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 3/79 (3%)

Query: 58  ATIH---PSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIAR 114
           A IH    SGL +LH A     +    +L K+GAD     + G+TPL +AC  G   +  
Sbjct: 686 ANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVN 745

Query: 115 YLISLGADRDATNDDGDLP 133
           +L+  GA+ +A   +G  P
Sbjct: 746 FLLKQGANVNAKTKNGYTP 764



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 32/107 (29%), Positives = 46/107 (42%)

Query: 27  RFPNDVLFLDHIRQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKY 86
           R  N +  L    QGD  +  + +   K  +  +    L ALH A   G+    KLL+  
Sbjct: 328 RTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDK 387

Query: 87  GADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
            A+ + R   G+TPLHIAC      +   L+  GA   A  + G  P
Sbjct: 388 RANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTP 434



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 24/68 (35%), Positives = 38/68 (55%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G   L  A   GN++ V  L+K GA+++ + + G+TPLH A   G+  I   L+  GA  
Sbjct: 728 GYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKP 787

Query: 124 DATNDDGD 131
           +AT  +G+
Sbjct: 788 NATTANGN 795



 Score = 45.1 bits (105), Expect = 2e-05
 Identities = 25/71 (35%), Positives = 33/71 (46%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G+  LH A   GN   VKLL+  G  I  +   G TPLH A   G+  +   L+  GA 
Sbjct: 265 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAP 324

Query: 123 RDATNDDGDLP 133
             A   +G  P
Sbjct: 325 LLARTKNGLSP 335



 Score = 43.9 bits (102), Expect = 5e-05
 Identities = 25/71 (35%), Positives = 33/71 (46%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           SG   LH A   GN+    LL+  GA +      G TPLH+A   G  ++ + L+  G  
Sbjct: 232 SGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQ 291

Query: 123 RDATNDDGDLP 133
            DA   DG  P
Sbjct: 292 IDAKTRDGLTP 302



 Score = 43.5 bits (101), Expect = 7e-05
 Identities = 26/70 (37%), Positives = 36/70 (51%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G  ALH A  +G +E V+ L++ GA +  R     TPLHIA   G  +I + L+   A  
Sbjct: 464 GETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHP 523

Query: 124 DATNDDGDLP 133
           DA   +G  P
Sbjct: 524 DAATTNGYTP 533



 Score = 43.1 bits (100), Expect = 9e-05
 Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 2/114 (1%)

Query: 17  RRRMLADRSVRFPNDVLFLDHIRQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGN 76
           +RR  AD + +  N +  L      D ++V   +  +  S      +G   LH A     
Sbjct: 584 QRRAAADSAGK--NGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQ 641

Query: 77  LECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDG 130
           ++    L+ YGA+ +   + G TPLH+A  +G+ D+   L+  GA+   +   G
Sbjct: 642 MQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSG 695



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 27/78 (34%), Positives = 38/78 (48%)

Query: 56  SLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARY 115
           S+  I  SGL  +H A   G+L  V LL++ GA     +  G T LH+A   G  ++ R 
Sbjct: 423 SIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRC 482

Query: 116 LISLGADRDATNDDGDLP 133
           L+  GA  DA   +   P
Sbjct: 483 LLRNGALVDARAREEQTP 500



 Score = 41.2 bits (95), Expect = 4e-04
 Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 2/78 (2%)

Query: 56  SLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARY 115
           SLAT    G   LH A   G+L+  KLL++  A      + G TPLH+A       +A  
Sbjct: 557 SLAT--KKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALL 614

Query: 116 LISLGADRDATNDDGDLP 133
           L+  GA   AT  +G  P
Sbjct: 615 LLEKGASPHATAKNGYTP 632



 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 23/66 (34%), Positives = 32/66 (48%)

Query: 68  LHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATN 127
           LH A   G  E V+LL+++ A        G+TPLHI+  +G  D+A  L+  GA      
Sbjct: 501 LHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLAT 560

Query: 128 DDGDLP 133
             G  P
Sbjct: 561 KKGFTP 566



 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 21/71 (29%), Positives = 36/71 (50%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH +   G ++   +L++ GA      + G+TPLH+A   G  D+A+ L+   A 
Sbjct: 529 NGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAA 588

Query: 123 RDATNDDGDLP 133
            D+   +G  P
Sbjct: 589 ADSAGKNGLTP 599



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 21/61 (34%), Positives = 35/61 (57%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           GL  LH A  SG+ + V+LL++ GA +  R + G +PLH+A    + +  ++L+   A  
Sbjct: 299 GLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPV 358

Query: 124 D 124
           D
Sbjct: 359 D 359



 Score = 37.7 bits (86), Expect = 0.004
 Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 8/77 (10%)

Query: 65  LAALHEAVLSGNLECVKLLVK--YGADIHQR------DEAGWTPLHIACSDGYPDIARYL 116
           L ALH A    + +   LL++  + AD+  +       E+G+TPLHIA   G  ++A  L
Sbjct: 193 LPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLL 252

Query: 117 ISLGADRDATNDDGDLP 133
           ++ GA  D T  +G  P
Sbjct: 253 LNRGAAVDFTARNGITP 269



 Score = 37.7 bits (86), Expect = 0.004
 Identities = 25/90 (27%), Positives = 43/90 (47%)

Query: 44  EQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHI 103
           +QV   +  R   L     +GL+ LH A    ++ECVK L+++ A +        T LH+
Sbjct: 312 DQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHV 371

Query: 104 ACSDGYPDIARYLISLGADRDATNDDGDLP 133
           A   G+  + + L+   A+ +A   +G  P
Sbjct: 372 AAHCGHYRVTKLLLDKRANPNARALNGFTP 401



 Score = 32.0 bits (71), Expect = 0.22
 Identities = 16/55 (29%), Positives = 28/55 (50%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLI 117
           +G   L+ A    +++ VK L++ GA+     E G+TPL +A   G+      L+
Sbjct: 129 NGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILL 183



 Score = 27.7 bits (60), Expect = 4.1
 Identities = 15/47 (31%), Positives = 24/47 (51%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGY 109
           +G   LH+A   G+   + +L+++GA  +     G T L IA   GY
Sbjct: 760 NGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGY 806


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 62.8 bits (151), Expect = 1e-10
 Identities = 31/81 (38%), Positives = 50/81 (61%)

Query: 53  RKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDI 112
           R  S+ +    G  ALH A L+G  E VK+LVK GA+I+ + + G+TPL++A  + + D+
Sbjct: 86  RGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDV 145

Query: 113 ARYLISLGADRDATNDDGDLP 133
            +YL+  GA++    +DG  P
Sbjct: 146 VKYLLENGANQSTATEDGFTP 166



 Score = 52.8 bits (125), Expect = 1e-07
 Identities = 27/69 (39%), Positives = 39/69 (56%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A     ++ ++LLVKYGA I    E+G TP+H+A   G+ +I   L+  GA 
Sbjct: 397 NGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGAS 456

Query: 123 RDATNDDGD 131
            D TN  G+
Sbjct: 457 PDVTNIRGE 465



 Score = 48.1 bits (113), Expect = 3e-06
 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 1/98 (1%)

Query: 39  RQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGW 98
           + G L+ V + +  R+ +  +   +GL  LH A    N +   LL++ GA  H   + G+
Sbjct: 572 KYGSLD-VAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGY 630

Query: 99  TPLHIACSDGYPDIARYLISLGADRDATNDDGDLPSDL 136
           TPLHIA       IA  L++ GA+ +     G  P  L
Sbjct: 631 TPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHL 668



 Score = 47.4 bits (111), Expect = 5e-06
 Identities = 26/70 (37%), Positives = 38/70 (54%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G+  LH A   G+ + V LL+  GA+IH   ++G T LH+A  +   ++A  L   GAD+
Sbjct: 662 GVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQ 721

Query: 124 DATNDDGDLP 133
           DA    G  P
Sbjct: 722 DAHTKLGYTP 731



 Score = 47.4 bits (111), Expect = 5e-06
 Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 3/79 (3%)

Query: 58  ATIH---PSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIAR 114
           A IH    SGL +LH A     +    +L K+GAD     + G+TPL +AC  G   +  
Sbjct: 686 ANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVN 745

Query: 115 YLISLGADRDATNDDGDLP 133
           +L+  GA+ +A   +G  P
Sbjct: 746 FLLKQGANVNAKTKNGYTP 764



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 32/107 (29%), Positives = 46/107 (42%)

Query: 27  RFPNDVLFLDHIRQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKY 86
           R  N +  L    QGD  +  + +   K  +  +    L ALH A   G+    KLL+  
Sbjct: 328 RTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDK 387

Query: 87  GADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
            A+ + R   G+TPLHIAC      +   L+  GA   A  + G  P
Sbjct: 388 RANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTP 434



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 24/68 (35%), Positives = 38/68 (55%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G   L  A   GN++ V  L+K GA+++ + + G+TPLH A   G+  I   L+  GA  
Sbjct: 728 GYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKP 787

Query: 124 DATNDDGD 131
           +AT  +G+
Sbjct: 788 NATTANGN 795



 Score = 45.1 bits (105), Expect = 2e-05
 Identities = 25/71 (35%), Positives = 33/71 (46%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G+  LH A   GN   VKLL+  G  I  +   G TPLH A   G+  +   L+  GA 
Sbjct: 265 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAP 324

Query: 123 RDATNDDGDLP 133
             A   +G  P
Sbjct: 325 LLARTKNGLSP 335



 Score = 43.9 bits (102), Expect = 5e-05
 Identities = 25/71 (35%), Positives = 33/71 (46%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           SG   LH A   GN+    LL+  GA +      G TPLH+A   G  ++ + L+  G  
Sbjct: 232 SGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQ 291

Query: 123 RDATNDDGDLP 133
            DA   DG  P
Sbjct: 292 IDAKTRDGLTP 302



 Score = 43.5 bits (101), Expect = 7e-05
 Identities = 26/70 (37%), Positives = 36/70 (51%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G  ALH A  +G +E V+ L++ GA +  R     TPLHIA   G  +I + L+   A  
Sbjct: 464 GETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHP 523

Query: 124 DATNDDGDLP 133
           DA   +G  P
Sbjct: 524 DAATTNGYTP 533



 Score = 43.1 bits (100), Expect = 9e-05
 Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 2/114 (1%)

Query: 17  RRRMLADRSVRFPNDVLFLDHIRQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGN 76
           +RR  AD + +  N +  L      D ++V   +  +  S      +G   LH A     
Sbjct: 584 QRRAAADSAGK--NGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQ 641

Query: 77  LECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDG 130
           ++    L+ YGA+ +   + G TPLH+A  +G+ D+   L+  GA+   +   G
Sbjct: 642 MQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSG 695



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 27/78 (34%), Positives = 38/78 (48%)

Query: 56  SLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARY 115
           S+  I  SGL  +H A   G+L  V LL++ GA     +  G T LH+A   G  ++ R 
Sbjct: 423 SIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRC 482

Query: 116 LISLGADRDATNDDGDLP 133
           L+  GA  DA   +   P
Sbjct: 483 LLRNGALVDARAREEQTP 500



 Score = 41.2 bits (95), Expect = 4e-04
 Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 2/78 (2%)

Query: 56  SLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARY 115
           SLAT    G   LH A   G+L+  KLL++  A      + G TPLH+A       +A  
Sbjct: 557 SLAT--KKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALL 614

Query: 116 LISLGADRDATNDDGDLP 133
           L+  GA   AT  +G  P
Sbjct: 615 LLEKGASPHATAKNGYTP 632



 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 23/66 (34%), Positives = 32/66 (48%)

Query: 68  LHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATN 127
           LH A   G  E V+LL+++ A        G+TPLHI+  +G  D+A  L+  GA      
Sbjct: 501 LHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLAT 560

Query: 128 DDGDLP 133
             G  P
Sbjct: 561 KKGFTP 566



 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 21/71 (29%), Positives = 36/71 (50%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH +   G ++   +L++ GA      + G+TPLH+A   G  D+A+ L+   A 
Sbjct: 529 NGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAA 588

Query: 123 RDATNDDGDLP 133
            D+   +G  P
Sbjct: 589 ADSAGKNGLTP 599



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 21/61 (34%), Positives = 35/61 (57%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           GL  LH A  SG+ + V+LL++ GA +  R + G +PLH+A    + +  ++L+   A  
Sbjct: 299 GLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPV 358

Query: 124 D 124
           D
Sbjct: 359 D 359



 Score = 37.7 bits (86), Expect = 0.004
 Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 8/77 (10%)

Query: 65  LAALHEAVLSGNLECVKLLVK--YGADIHQR------DEAGWTPLHIACSDGYPDIARYL 116
           L ALH A    + +   LL++  + AD+  +       E+G+TPLHIA   G  ++A  L
Sbjct: 193 LPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLL 252

Query: 117 ISLGADRDATNDDGDLP 133
           ++ GA  D T  +G  P
Sbjct: 253 LNRGAAVDFTARNGITP 269



 Score = 37.7 bits (86), Expect = 0.004
 Identities = 25/90 (27%), Positives = 43/90 (47%)

Query: 44  EQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHI 103
           +QV   +  R   L     +GL+ LH A    ++ECVK L+++ A +        T LH+
Sbjct: 312 DQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHV 371

Query: 104 ACSDGYPDIARYLISLGADRDATNDDGDLP 133
           A   G+  + + L+   A+ +A   +G  P
Sbjct: 372 AAHCGHYRVTKLLLDKRANPNARALNGFTP 401



 Score = 32.0 bits (71), Expect = 0.22
 Identities = 16/55 (29%), Positives = 28/55 (50%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLI 117
           +G   L+ A    +++ VK L++ GA+     E G+TPL +A   G+      L+
Sbjct: 129 NGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILL 183



 Score = 27.7 bits (60), Expect = 4.1
 Identities = 15/47 (31%), Positives = 24/47 (51%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGY 109
           +G   LH+A   G+   + +L+++GA  +     G T L IA   GY
Sbjct: 760 NGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGY 806


>gi|68131557 ankyrin repeat domain 28 [Homo sapiens]
          Length = 1053

 Score = 62.0 bits (149), Expect = 2e-10
 Identities = 29/86 (33%), Positives = 48/86 (55%)

Query: 48  RFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSD 107
           + + +R  ++         A+H A   G++E VKLLV +GA++  +D+  +TPLH A S 
Sbjct: 157 KLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASS 216

Query: 108 GYPDIARYLISLGADRDATNDDGDLP 133
           G   + +YL+ LG D +  N  G+ P
Sbjct: 217 GMISVVKYLLDLGVDMNEPNAYGNTP 242



 Score = 48.5 bits (114), Expect = 2e-06
 Identities = 25/66 (37%), Positives = 36/66 (54%)

Query: 68  LHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATN 127
           LH A  SG +  VK L+  G D+++ +  G TPLH+AC +G   +   LI  GA  +  N
Sbjct: 210 LHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKN 269

Query: 128 DDGDLP 133
           + G  P
Sbjct: 270 EKGFTP 275



 Score = 48.5 bits (114), Expect = 2e-06
 Identities = 25/70 (35%), Positives = 38/70 (54%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G   LH A   GNLEC+ LL+  GAD +++D+ G +PLH A ++        L+  GA  
Sbjct: 405 GRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASV 464

Query: 124 DATNDDGDLP 133
           +  ++ G  P
Sbjct: 465 NDLDERGCTP 474



 Score = 46.6 bits (109), Expect = 8e-06
 Identities = 23/68 (33%), Positives = 36/68 (52%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G  ALH   ++G+ ECV  L+++GA    RD  G TP+H++ + G+  +   L+   A  
Sbjct: 686 GRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASM 745

Query: 124 DATNDDGD 131
           DA     D
Sbjct: 746 DANPATAD 753



 Score = 45.4 bits (106), Expect = 2e-05
 Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 5/89 (5%)

Query: 47  GRFIRTRKV--SLATIH---PSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPL 101
           GRF R++ +  S A I     +G   LH A   G+   +  L+  GAD  +R   G  PL
Sbjct: 317 GRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPL 376

Query: 102 HIACSDGYPDIARYLISLGADRDATNDDG 130
           H+A   G+ D  R L+S G D D  +D G
Sbjct: 377 HLAALSGFSDCCRKLLSSGFDIDTPDDFG 405



 Score = 43.5 bits (101), Expect = 7e-05
 Identities = 23/55 (41%), Positives = 34/55 (61%)

Query: 65  LAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISL 119
           L  LH AV S + E V++L+K+ AD++ RD+   TPLHIA ++     A  L+ L
Sbjct: 75  LTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPL 129



 Score = 43.1 bits (100), Expect = 9e-05
 Identities = 25/70 (35%), Positives = 36/70 (51%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G+  LH A LSG  +C + L+  G DI   D+ G T LH A + G  +    L++ GAD 
Sbjct: 372 GMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADF 431

Query: 124 DATNDDGDLP 133
           +  +  G  P
Sbjct: 432 NKKDKFGRSP 441



 Score = 41.6 bits (96), Expect = 3e-04
 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 1/71 (1%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIA-RYLISLGAD 122
           G   LH A  +G    V  L+  GA ++Q++E G+TPLH A +  +  +    L+  GAD
Sbjct: 239 GNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGAD 298

Query: 123 RDATNDDGDLP 133
            +  + DG  P
Sbjct: 299 VNMKSKDGKTP 309



 Score = 41.2 bits (95), Expect = 4e-04
 Identities = 18/55 (32%), Positives = 31/55 (56%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLIS 118
           G   LH A  + ++EC++LL+ + A ++  D  G TPL +A  +G  +    L+S
Sbjct: 823 GRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVS 877



 Score = 40.4 bits (93), Expect = 6e-04
 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 1/71 (1%)

Query: 64  GLAALHEAVLSGN-LECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           G   LH A  S +   C++LLV  GAD++ + + G TPLH+    G    ++ +I  GA 
Sbjct: 272 GFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAV 331

Query: 123 RDATNDDGDLP 133
            D  + +G+ P
Sbjct: 332 IDCEDKNGNTP 342



 Score = 39.3 bits (90), Expect = 0.001
 Identities = 25/73 (34%), Positives = 33/73 (45%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G   LH   L G     + +++ GA I   D+ G TPLHIA   G+  +   LI+ GAD 
Sbjct: 306 GKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADT 365

Query: 124 DATNDDGDLPSDL 136
                 G  P  L
Sbjct: 366 AKRGIHGMFPLHL 378



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 2/71 (2%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEA-GWTPLHIACSDGYPDIARYLISLGA 121
           SG   L  A   G++ECV +L+  GA I  +D     TP+H A ++G+ +  R LI    
Sbjct: 582 SGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAE 641

Query: 122 DRDATN-DDGD 131
            ++A +  DG+
Sbjct: 642 PQNAVDIQDGN 652



 Score = 38.1 bits (87), Expect = 0.003
 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 1/68 (1%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIAC-SDGYPDIARYLISLGAD 122
           G + LH A  + N +C+  LV  GA ++  DE G TPLH A  SD       YL+   A+
Sbjct: 438 GRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDAN 497

Query: 123 RDATNDDG 130
               +  G
Sbjct: 498 PGIRDKQG 505



 Score = 37.7 bits (86), Expect = 0.004
 Identities = 20/66 (30%), Positives = 34/66 (51%)

Query: 68  LHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATN 127
           LH A   G+ E ++LL+  GA ++ +D    TPLH A +    +  + L+   AD +A +
Sbjct: 45  LHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARD 104

Query: 128 DDGDLP 133
            +   P
Sbjct: 105 KNWQTP 110



 Score = 37.0 bits (84), Expect = 0.007
 Identities = 19/58 (32%), Positives = 34/58 (58%)

Query: 68  LHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDA 125
           LH A  +  ++C + LV   ++++  D AG T LH A   G+ ++ + L+S GA+ +A
Sbjct: 111 LHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINA 168



 Score = 36.6 bits (83), Expect = 0.009
 Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 5/64 (7%)

Query: 58  ATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLI 117
           ATI P  LAA H     G+ + +++LV+   D+  R+ +G TPL +A   G+ +    LI
Sbjct: 549 ATISPLHLAAYH-----GHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLI 603

Query: 118 SLGA 121
           + GA
Sbjct: 604 NQGA 607



 Score = 35.8 bits (81), Expect = 0.015
 Identities = 19/59 (32%), Positives = 32/59 (54%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGA 121
           +G   L  +VL+G+ +CV  L+  GA++  +D+ G T LH     G+ +    L+  GA
Sbjct: 652 NGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGA 710



 Score = 35.4 bits (80), Expect = 0.019
 Identities = 22/68 (32%), Positives = 38/68 (55%), Gaps = 7/68 (10%)

Query: 68  LHEAVLSGNLECVKLLV-----KYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +H A  +G+ EC++LL+     +   DI  +D  G TPL ++  +G+ D    L++ GA+
Sbjct: 621 IHAAATNGHSECLRLLIGNAEPQNAVDI--QDGNGQTPLMLSVLNGHTDCVYSLLNKGAN 678

Query: 123 RDATNDDG 130
            DA +  G
Sbjct: 679 VDAKDKWG 686



 Score = 33.9 bits (76), Expect = 0.057
 Identities = 28/79 (35%), Positives = 42/79 (53%), Gaps = 5/79 (6%)

Query: 58  ATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEA-GWTPLHIACSDGYPDIARYL 116
           AT    G  ALH A  +G+  CV+LL++   ++ Q+ E   ++PLH A  +     A  L
Sbjct: 750 ATADNHGYTALHWACYNGHETCVELLLE--QEVFQKTEGNAFSPLHCAVINDNEGAAEML 807

Query: 117 I-SLGAD-RDATNDDGDLP 133
           I +LGA   +AT+  G  P
Sbjct: 808 IDTLGASIVNATDSKGRTP 826



 Score = 32.7 bits (73), Expect = 0.13
 Identities = 30/118 (25%), Positives = 49/118 (41%), Gaps = 5/118 (4%)

Query: 41  GDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGAD---IHQRDEAG 97
           G    V   + +    L     S   ALH A   G+     L+++   D   I+  + A 
Sbjct: 867 GQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAAL 926

Query: 98  WTPLHIACSDGYPDIARYLISLGADRDATNDDGDLPSDLIDP--DYKELVELFKGTTM 153
            TPLH+A  +G   + + L+  GA   A +++G  P+    P  D  + + L   T M
Sbjct: 927 QTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILATMM 984



 Score = 31.2 bits (69), Expect = 0.37
 Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 2/73 (2%)

Query: 63  SGLAALHEAVLSGNLECVKLLVK-YGADI-HQRDEAGWTPLHIACSDGYPDIARYLISLG 120
           +  + LH AV++ N    ++L+   GA I +  D  G TPLH A    + +  + L+S  
Sbjct: 787 NAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHN 846

Query: 121 ADRDATNDDGDLP 133
           A  ++ +  G  P
Sbjct: 847 AQVNSVDSTGKTP 859



 Score = 30.4 bits (67), Expect = 0.63
 Identities = 18/55 (32%), Positives = 30/55 (54%)

Query: 67  ALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGA 121
           +L +A+ +G+ + V+ L+    D++ +D    TPLH A   G  +I   LI  GA
Sbjct: 11  SLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGA 65



 Score = 29.3 bits (64), Expect = 1.4
 Identities = 22/85 (25%), Positives = 34/85 (40%), Gaps = 12/85 (14%)

Query: 64  GLAALHEAVLSGNLECVKLLVKY----------GADI--HQRDEAGWTPLHIACSDGYPD 111
           G  A+H +   G+  C++L+             G D+     + A  +PLH+A   G+  
Sbjct: 505 GYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQ 564

Query: 112 IARYLISLGADRDATNDDGDLPSDL 136
               L+    D D  N  G  P DL
Sbjct: 565 ALEVLVQSLLDLDVRNSSGRTPLDL 589


>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
          Length = 1897

 Score = 62.0 bits (149), Expect = 2e-10
 Identities = 29/95 (30%), Positives = 58/95 (61%), Gaps = 1/95 (1%)

Query: 39  RQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGW 98
           ++G ++ V   +  +++ L T    G  ALH A L+G  E V+ LV YGA+++ + + G+
Sbjct: 87  KEGHVKMVVELLH-KEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGF 145

Query: 99  TPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           TPL++A  + + ++ ++L+  GA+++   +DG  P
Sbjct: 146 TPLYMAAQENHLEVVKFLLENGANQNVATEDGFTP 180



 Score = 53.5 bits (127), Expect = 7e-08
 Identities = 25/70 (35%), Positives = 40/70 (57%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G   LH A   GN++ VK L+++ AD++ + + G++PLH A   G+ DI   L+  GA  
Sbjct: 734 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASP 793

Query: 124 DATNDDGDLP 133
           +  + DG  P
Sbjct: 794 NEVSSDGTTP 803



 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 32/86 (37%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +GL  LH AV   NL+ VKLL+  G   H     G+TPLHIA      ++AR L+  G  
Sbjct: 601 NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGS 660

Query: 123 RDATNDDGDLPSDLIDPD-YKELVEL 147
            +A +  G  P  L   + + E+V L
Sbjct: 661 ANAESVQGVTPLHLAAQEGHAEMVAL 686



 Score = 47.4 bits (111), Expect = 5e-06
 Identities = 34/119 (28%), Positives = 57/119 (47%), Gaps = 1/119 (0%)

Query: 15  QRRRRMLADRSVRFPNDVLFLDHIRQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLS 74
           ++RR    DR  +      FL   R G+L++    +R   V + T + +GL  LH A   
Sbjct: 30  RKRRNRSRDRKKKADAATSFLRAARSGNLDKALDHLRNG-VDINTCNQNGLNGLHLASKE 88

Query: 75  GNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           G+++ V  L+     +    + G T LHIA   G  ++ R L++ GA+ +A +  G  P
Sbjct: 89  GHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTP 147



 Score = 47.4 bits (111), Expect = 5e-06
 Identities = 30/94 (31%), Positives = 41/94 (43%)

Query: 40  QGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWT 99
           QGD     R +      +  I    L  LH A   G+    K+L+  GA  + R   G+T
Sbjct: 347 QGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFT 406

Query: 100 PLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           PLHIAC   +  +   L+  GA  DA  + G  P
Sbjct: 407 PLHIACKKNHVRVMELLLKTGASIDAVTESGLTP 440



 Score = 46.6 bits (109), Expect = 8e-06
 Identities = 24/71 (33%), Positives = 41/71 (57%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +GL+ +H A    +L+CV+LL++Y A+I        TPLH+A   G+  +A+ L+  GA 
Sbjct: 337 NGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAK 396

Query: 123 RDATNDDGDLP 133
            ++   +G  P
Sbjct: 397 PNSRALNGFTP 407



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 27/78 (34%), Positives = 41/78 (52%)

Query: 56  SLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARY 115
           S+  +  SGL  LH A   G+L  VK L++ GA  +  +    TPLH+A   G+ ++A+Y
Sbjct: 429 SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKY 488

Query: 116 LISLGADRDATNDDGDLP 133
           L+   A  +A   D   P
Sbjct: 489 LLQNKAKVNAKAKDDQTP 506



 Score = 45.1 bits (105), Expect = 2e-05
 Identities = 28/88 (31%), Positives = 43/88 (48%)

Query: 46  VGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIAC 105
           V + +  R  S+     +G+  LH A   GN+  V+LL+  GA I  + +   TPLH A 
Sbjct: 254 VAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAA 313

Query: 106 SDGYPDIARYLISLGADRDATNDDGDLP 133
            +G+  I+  L+  GA   A   +G  P
Sbjct: 314 RNGHVRISEILLDHGAPIQAKTKNGLSP 341



 Score = 44.3 bits (103), Expect = 4e-05
 Identities = 24/71 (33%), Positives = 38/71 (53%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A    ++  ++LL+K GA I    E+G TPLH+A   G+  I + L+  GA 
Sbjct: 403 NGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS 462

Query: 123 RDATNDDGDLP 133
            + +N   + P
Sbjct: 463 PNVSNVKVETP 473



 Score = 44.3 bits (103), Expect = 4e-05
 Identities = 22/75 (29%), Positives = 37/75 (49%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A     +E  + L++YG   +     G TPLH+A  +G+ ++   L+S  A+
Sbjct: 634 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 693

Query: 123 RDATNDDGDLPSDLI 137
            +  N  G  P  L+
Sbjct: 694 GNLGNKSGLTPLHLV 708



 Score = 43.5 bits (101), Expect = 7e-05
 Identities = 25/70 (35%), Positives = 37/70 (52%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G+  LH A   G+ E V LL+   A+ +  +++G TPLH+   +G+  +A  LI  G   
Sbjct: 668 GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMV 727

Query: 124 DATNDDGDLP 133
           DAT   G  P
Sbjct: 728 DATTRMGYTP 737



 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 22/71 (30%), Positives = 35/71 (49%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           SGL  LH     G++    +L+K+G  +      G+TPLH+A   G   + ++L+   AD
Sbjct: 700 SGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQAD 759

Query: 123 RDATNDDGDLP 133
            +A    G  P
Sbjct: 760 VNAKTKLGYSP 770



 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 20/57 (35%), Positives = 33/57 (57%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLG 120
           G   L+ A    +LE VK L++ GA+ +   E G+TPL +A   G+ ++  +LI+ G
Sbjct: 144 GFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG 200



 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 39  RQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGW 98
           R+G++  V R +  R   + T     L  LH A  +G++   ++L+ +GA I  + + G 
Sbjct: 281 RRGNVIMV-RLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGL 339

Query: 99  TPLHIACSDGYPDIARYLISLGADRD 124
           +P+H+A    + D  R L+   A+ D
Sbjct: 340 SPIHMAAQGDHLDCVRLLLQYDAEID 365



 Score = 39.3 bits (90), Expect = 0.001
 Identities = 23/67 (34%), Positives = 32/67 (47%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A    NL   +LL+  GA ++   + G TPLHIA   G   + R L+  GA 
Sbjct: 238 TGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQ 297

Query: 123 RDATNDD 129
            +    D
Sbjct: 298 IETKTKD 304



 Score = 38.1 bits (87), Expect = 0.003
 Identities = 24/89 (26%), Positives = 39/89 (43%)

Query: 45  QVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIA 104
           +V +++   K  +          LH A   G+   VKLL++  A+ +    AG TPLHIA
Sbjct: 484 EVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIA 543

Query: 105 CSDGYPDIARYLISLGADRDATNDDGDLP 133
             +G+ +    L+   A +      G  P
Sbjct: 544 AREGHVETVLALLEKEASQACMTKKGFTP 572



 Score = 37.7 bits (86), Expect = 0.004
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 1/95 (1%)

Query: 39  RQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGW 98
           R+G +E V   +  ++ S A +   G   LH A   G +   +LL++  A  +   + G 
Sbjct: 545 REGHVETVLALLE-KEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGL 603

Query: 99  TPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           TPLH+A      DI + L+  G    +   +G  P
Sbjct: 604 TPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTP 638



 Score = 35.8 bits (81), Expect = 0.015
 Identities = 22/71 (30%), Positives = 34/71 (47%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A   G++E V  L++  A      + G+TPLH+A   G   +A  L+   A 
Sbjct: 535 AGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAH 594

Query: 123 RDATNDDGDLP 133
            +A   +G  P
Sbjct: 595 PNAAGKNGLTP 605



 Score = 35.4 bits (80), Expect = 0.019
 Identities = 20/53 (37%), Positives = 28/53 (52%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYL 116
           G + LH+A   G+ + V LL+K GA  ++    G TPL IA   GY  +   L
Sbjct: 767 GYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 819



 Score = 34.7 bits (78), Expect = 0.033
 Identities = 18/66 (27%), Positives = 33/66 (50%)

Query: 68  LHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATN 127
           LH A  +G+ E  K L++  A ++ + +   TPLH A   G+ ++ + L+   A+ +   
Sbjct: 474 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 533

Query: 128 DDGDLP 133
             G  P
Sbjct: 534 TAGHTP 539



 Score = 32.7 bits (73), Expect = 0.13
 Identities = 20/69 (28%), Positives = 35/69 (50%)

Query: 65  LAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRD 124
           L ALH A  + +     +L++   +     + G+TPLHIA      ++A+ L++ GA  +
Sbjct: 207 LPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVN 266

Query: 125 ATNDDGDLP 133
            T  +G  P
Sbjct: 267 FTPQNGITP 275


>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
          Length = 1881

 Score = 62.0 bits (149), Expect = 2e-10
 Identities = 29/95 (30%), Positives = 58/95 (61%), Gaps = 1/95 (1%)

Query: 39  RQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGW 98
           ++G ++ V   +  +++ L T    G  ALH A L+G  E V+ LV YGA+++ + + G+
Sbjct: 54  KEGHVKMVVELLH-KEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGF 112

Query: 99  TPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           TPL++A  + + ++ ++L+  GA+++   +DG  P
Sbjct: 113 TPLYMAAQENHLEVVKFLLENGANQNVATEDGFTP 147



 Score = 53.5 bits (127), Expect = 7e-08
 Identities = 25/70 (35%), Positives = 40/70 (57%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G   LH A   GN++ VK L+++ AD++ + + G++PLH A   G+ DI   L+  GA  
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASP 760

Query: 124 DATNDDGDLP 133
           +  + DG  P
Sbjct: 761 NEVSSDGTTP 770



 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 32/86 (37%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +GL  LH AV   NL+ VKLL+  G   H     G+TPLHIA      ++AR L+  G  
Sbjct: 568 NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGS 627

Query: 123 RDATNDDGDLPSDLIDPD-YKELVEL 147
            +A +  G  P  L   + + E+V L
Sbjct: 628 ANAESVQGVTPLHLAAQEGHAEMVAL 653



 Score = 47.4 bits (111), Expect = 5e-06
 Identities = 30/94 (31%), Positives = 41/94 (43%)

Query: 40  QGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWT 99
           QGD     R +      +  I    L  LH A   G+    K+L+  GA  + R   G+T
Sbjct: 314 QGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFT 373

Query: 100 PLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           PLHIAC   +  +   L+  GA  DA  + G  P
Sbjct: 374 PLHIACKKNHVRVMELLLKTGASIDAVTESGLTP 407



 Score = 46.6 bits (109), Expect = 8e-06
 Identities = 24/71 (33%), Positives = 41/71 (57%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +GL+ +H A    +L+CV+LL++Y A+I        TPLH+A   G+  +A+ L+  GA 
Sbjct: 304 NGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAK 363

Query: 123 RDATNDDGDLP 133
            ++   +G  P
Sbjct: 364 PNSRALNGFTP 374



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 27/78 (34%), Positives = 41/78 (52%)

Query: 56  SLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARY 115
           S+  +  SGL  LH A   G+L  VK L++ GA  +  +    TPLH+A   G+ ++A+Y
Sbjct: 396 SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKY 455

Query: 116 LISLGADRDATNDDGDLP 133
           L+   A  +A   D   P
Sbjct: 456 LLQNKAKVNAKAKDDQTP 473



 Score = 45.1 bits (105), Expect = 2e-05
 Identities = 28/88 (31%), Positives = 43/88 (48%)

Query: 46  VGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIAC 105
           V + +  R  S+     +G+  LH A   GN+  V+LL+  GA I  + +   TPLH A 
Sbjct: 221 VAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAA 280

Query: 106 SDGYPDIARYLISLGADRDATNDDGDLP 133
            +G+  I+  L+  GA   A   +G  P
Sbjct: 281 RNGHVRISEILLDHGAPIQAKTKNGLSP 308



 Score = 44.3 bits (103), Expect = 4e-05
 Identities = 24/71 (33%), Positives = 38/71 (53%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A    ++  ++LL+K GA I    E+G TPLH+A   G+  I + L+  GA 
Sbjct: 370 NGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS 429

Query: 123 RDATNDDGDLP 133
            + +N   + P
Sbjct: 430 PNVSNVKVETP 440



 Score = 44.3 bits (103), Expect = 4e-05
 Identities = 22/75 (29%), Positives = 37/75 (49%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A     +E  + L++YG   +     G TPLH+A  +G+ ++   L+S  A+
Sbjct: 601 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 660

Query: 123 RDATNDDGDLPSDLI 137
            +  N  G  P  L+
Sbjct: 661 GNLGNKSGLTPLHLV 675



 Score = 43.5 bits (101), Expect = 7e-05
 Identities = 25/70 (35%), Positives = 37/70 (52%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G+  LH A   G+ E V LL+   A+ +  +++G TPLH+   +G+  +A  LI  G   
Sbjct: 635 GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMV 694

Query: 124 DATNDDGDLP 133
           DAT   G  P
Sbjct: 695 DATTRMGYTP 704



 Score = 43.1 bits (100), Expect = 9e-05
 Identities = 30/100 (30%), Positives = 50/100 (50%), Gaps = 1/100 (1%)

Query: 34  FLDHIRQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQR 93
           FL   R G+L++    +R   V + T + +GL  LH A   G+++ V  L+     +   
Sbjct: 16  FLRAARSGNLDKALDHLRNG-VDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETT 74

Query: 94  DEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
            + G T LHIA   G  ++ R L++ GA+ +A +  G  P
Sbjct: 75  TKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTP 114



 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 22/71 (30%), Positives = 35/71 (49%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           SGL  LH     G++    +L+K+G  +      G+TPLH+A   G   + ++L+   AD
Sbjct: 667 SGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQAD 726

Query: 123 RDATNDDGDLP 133
            +A    G  P
Sbjct: 727 VNAKTKLGYSP 737



 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 20/57 (35%), Positives = 33/57 (57%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLG 120
           G   L+ A    +LE VK L++ GA+ +   E G+TPL +A   G+ ++  +LI+ G
Sbjct: 111 GFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG 167



 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 39  RQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGW 98
           R+G++  V R +  R   + T     L  LH A  +G++   ++L+ +GA I  + + G 
Sbjct: 248 RRGNVIMV-RLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGL 306

Query: 99  TPLHIACSDGYPDIARYLISLGADRD 124
           +P+H+A    + D  R L+   A+ D
Sbjct: 307 SPIHMAAQGDHLDCVRLLLQYDAEID 332



 Score = 39.3 bits (90), Expect = 0.001
 Identities = 23/67 (34%), Positives = 32/67 (47%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A    NL   +LL+  GA ++   + G TPLHIA   G   + R L+  GA 
Sbjct: 205 TGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQ 264

Query: 123 RDATNDD 129
            +    D
Sbjct: 265 IETKTKD 271



 Score = 38.1 bits (87), Expect = 0.003
 Identities = 24/89 (26%), Positives = 39/89 (43%)

Query: 45  QVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIA 104
           +V +++   K  +          LH A   G+   VKLL++  A+ +    AG TPLHIA
Sbjct: 451 EVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIA 510

Query: 105 CSDGYPDIARYLISLGADRDATNDDGDLP 133
             +G+ +    L+   A +      G  P
Sbjct: 511 AREGHVETVLALLEKEASQACMTKKGFTP 539



 Score = 37.7 bits (86), Expect = 0.004
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 1/95 (1%)

Query: 39  RQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGW 98
           R+G +E V   +  ++ S A +   G   LH A   G +   +LL++  A  +   + G 
Sbjct: 512 REGHVETVLALLE-KEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGL 570

Query: 99  TPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           TPLH+A      DI + L+  G    +   +G  P
Sbjct: 571 TPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTP 605



 Score = 35.8 bits (81), Expect = 0.015
 Identities = 22/71 (30%), Positives = 34/71 (47%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A   G++E V  L++  A      + G+TPLH+A   G   +A  L+   A 
Sbjct: 502 AGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAH 561

Query: 123 RDATNDDGDLP 133
            +A   +G  P
Sbjct: 562 PNAAGKNGLTP 572



 Score = 35.4 bits (80), Expect = 0.019
 Identities = 20/53 (37%), Positives = 28/53 (52%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYL 116
           G + LH+A   G+ + V LL+K GA  ++    G TPL IA   GY  +   L
Sbjct: 734 GYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786



 Score = 34.7 bits (78), Expect = 0.033
 Identities = 18/66 (27%), Positives = 33/66 (50%)

Query: 68  LHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATN 127
           LH A  +G+ E  K L++  A ++ + +   TPLH A   G+ ++ + L+   A+ +   
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 500

Query: 128 DDGDLP 133
             G  P
Sbjct: 501 TAGHTP 506



 Score = 32.7 bits (73), Expect = 0.13
 Identities = 20/69 (28%), Positives = 35/69 (50%)

Query: 65  LAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRD 124
           L ALH A  + +     +L++   +     + G+TPLHIA      ++A+ L++ GA  +
Sbjct: 174 LPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVN 233

Query: 125 ATNDDGDLP 133
            T  +G  P
Sbjct: 234 FTPQNGITP 242


>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
          Length = 1880

 Score = 62.0 bits (149), Expect = 2e-10
 Identities = 29/95 (30%), Positives = 58/95 (61%), Gaps = 1/95 (1%)

Query: 39  RQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGW 98
           ++G ++ V   +  +++ L T    G  ALH A L+G  E V+ LV YGA+++ + + G+
Sbjct: 54  KEGHVKMVVELLH-KEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGF 112

Query: 99  TPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           TPL++A  + + ++ ++L+  GA+++   +DG  P
Sbjct: 113 TPLYMAAQENHLEVVKFLLENGANQNVATEDGFTP 147



 Score = 53.5 bits (127), Expect = 7e-08
 Identities = 25/70 (35%), Positives = 40/70 (57%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G   LH A   GN++ VK L+++ AD++ + + G++PLH A   G+ DI   L+  GA  
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASP 760

Query: 124 DATNDDGDLP 133
           +  + DG  P
Sbjct: 761 NEVSSDGTTP 770



 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 32/86 (37%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +GL  LH AV   NL+ VKLL+  G   H     G+TPLHIA      ++AR L+  G  
Sbjct: 568 NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGS 627

Query: 123 RDATNDDGDLPSDLIDPD-YKELVEL 147
            +A +  G  P  L   + + E+V L
Sbjct: 628 ANAESVQGVTPLHLAAQEGHAEMVAL 653



 Score = 47.4 bits (111), Expect = 5e-06
 Identities = 30/94 (31%), Positives = 41/94 (43%)

Query: 40  QGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWT 99
           QGD     R +      +  I    L  LH A   G+    K+L+  GA  + R   G+T
Sbjct: 314 QGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFT 373

Query: 100 PLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           PLHIAC   +  +   L+  GA  DA  + G  P
Sbjct: 374 PLHIACKKNHVRVMELLLKTGASIDAVTESGLTP 407



 Score = 46.6 bits (109), Expect = 8e-06
 Identities = 24/71 (33%), Positives = 41/71 (57%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +GL+ +H A    +L+CV+LL++Y A+I        TPLH+A   G+  +A+ L+  GA 
Sbjct: 304 NGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAK 363

Query: 123 RDATNDDGDLP 133
            ++   +G  P
Sbjct: 364 PNSRALNGFTP 374



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 27/78 (34%), Positives = 41/78 (52%)

Query: 56  SLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARY 115
           S+  +  SGL  LH A   G+L  VK L++ GA  +  +    TPLH+A   G+ ++A+Y
Sbjct: 396 SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKY 455

Query: 116 LISLGADRDATNDDGDLP 133
           L+   A  +A   D   P
Sbjct: 456 LLQNKAKVNAKAKDDQTP 473



 Score = 45.1 bits (105), Expect = 2e-05
 Identities = 28/88 (31%), Positives = 43/88 (48%)

Query: 46  VGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIAC 105
           V + +  R  S+     +G+  LH A   GN+  V+LL+  GA I  + +   TPLH A 
Sbjct: 221 VAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAA 280

Query: 106 SDGYPDIARYLISLGADRDATNDDGDLP 133
            +G+  I+  L+  GA   A   +G  P
Sbjct: 281 RNGHVRISEILLDHGAPIQAKTKNGLSP 308



 Score = 44.3 bits (103), Expect = 4e-05
 Identities = 24/71 (33%), Positives = 38/71 (53%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A    ++  ++LL+K GA I    E+G TPLH+A   G+  I + L+  GA 
Sbjct: 370 NGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS 429

Query: 123 RDATNDDGDLP 133
            + +N   + P
Sbjct: 430 PNVSNVKVETP 440



 Score = 44.3 bits (103), Expect = 4e-05
 Identities = 22/75 (29%), Positives = 37/75 (49%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A     +E  + L++YG   +     G TPLH+A  +G+ ++   L+S  A+
Sbjct: 601 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 660

Query: 123 RDATNDDGDLPSDLI 137
            +  N  G  P  L+
Sbjct: 661 GNLGNKSGLTPLHLV 675



 Score = 43.5 bits (101), Expect = 7e-05
 Identities = 25/70 (35%), Positives = 37/70 (52%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G+  LH A   G+ E V LL+   A+ +  +++G TPLH+   +G+  +A  LI  G   
Sbjct: 635 GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMV 694

Query: 124 DATNDDGDLP 133
           DAT   G  P
Sbjct: 695 DATTRMGYTP 704



 Score = 43.1 bits (100), Expect = 9e-05
 Identities = 30/100 (30%), Positives = 50/100 (50%), Gaps = 1/100 (1%)

Query: 34  FLDHIRQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQR 93
           FL   R G+L++    +R   V + T + +GL  LH A   G+++ V  L+     +   
Sbjct: 16  FLRAARSGNLDKALDHLRNG-VDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETT 74

Query: 94  DEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
            + G T LHIA   G  ++ R L++ GA+ +A +  G  P
Sbjct: 75  TKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTP 114



 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 22/71 (30%), Positives = 35/71 (49%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           SGL  LH     G++    +L+K+G  +      G+TPLH+A   G   + ++L+   AD
Sbjct: 667 SGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQAD 726

Query: 123 RDATNDDGDLP 133
            +A    G  P
Sbjct: 727 VNAKTKLGYSP 737



 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 20/57 (35%), Positives = 33/57 (57%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLG 120
           G   L+ A    +LE VK L++ GA+ +   E G+TPL +A   G+ ++  +LI+ G
Sbjct: 111 GFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG 167



 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 39  RQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGW 98
           R+G++  V R +  R   + T     L  LH A  +G++   ++L+ +GA I  + + G 
Sbjct: 248 RRGNVIMV-RLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGL 306

Query: 99  TPLHIACSDGYPDIARYLISLGADRD 124
           +P+H+A    + D  R L+   A+ D
Sbjct: 307 SPIHMAAQGDHLDCVRLLLQYDAEID 332



 Score = 39.3 bits (90), Expect = 0.001
 Identities = 23/67 (34%), Positives = 32/67 (47%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A    NL   +LL+  GA ++   + G TPLHIA   G   + R L+  GA 
Sbjct: 205 TGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQ 264

Query: 123 RDATNDD 129
            +    D
Sbjct: 265 IETKTKD 271



 Score = 38.1 bits (87), Expect = 0.003
 Identities = 24/89 (26%), Positives = 39/89 (43%)

Query: 45  QVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIA 104
           +V +++   K  +          LH A   G+   VKLL++  A+ +    AG TPLHIA
Sbjct: 451 EVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIA 510

Query: 105 CSDGYPDIARYLISLGADRDATNDDGDLP 133
             +G+ +    L+   A +      G  P
Sbjct: 511 AREGHVETVLALLEKEASQACMTKKGFTP 539



 Score = 37.7 bits (86), Expect = 0.004
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 1/95 (1%)

Query: 39  RQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGW 98
           R+G +E V   +  ++ S A +   G   LH A   G +   +LL++  A  +   + G 
Sbjct: 512 REGHVETVLALLE-KEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGL 570

Query: 99  TPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           TPLH+A      DI + L+  G    +   +G  P
Sbjct: 571 TPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTP 605



 Score = 35.8 bits (81), Expect = 0.015
 Identities = 22/71 (30%), Positives = 34/71 (47%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A   G++E V  L++  A      + G+TPLH+A   G   +A  L+   A 
Sbjct: 502 AGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAH 561

Query: 123 RDATNDDGDLP 133
            +A   +G  P
Sbjct: 562 PNAAGKNGLTP 572



 Score = 35.4 bits (80), Expect = 0.019
 Identities = 20/53 (37%), Positives = 28/53 (52%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYL 116
           G + LH+A   G+ + V LL+K GA  ++    G TPL IA   GY  +   L
Sbjct: 734 GYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786



 Score = 34.7 bits (78), Expect = 0.033
 Identities = 18/66 (27%), Positives = 33/66 (50%)

Query: 68  LHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATN 127
           LH A  +G+ E  K L++  A ++ + +   TPLH A   G+ ++ + L+   A+ +   
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 500

Query: 128 DDGDLP 133
             G  P
Sbjct: 501 TAGHTP 506



 Score = 32.7 bits (73), Expect = 0.13
 Identities = 20/69 (28%), Positives = 35/69 (50%)

Query: 65  LAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRD 124
           L ALH A  + +     +L++   +     + G+TPLHIA      ++A+ L++ GA  +
Sbjct: 174 LPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVN 233

Query: 125 ATNDDGDLP 133
            T  +G  P
Sbjct: 234 FTPQNGITP 242


>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
          Length = 1719

 Score = 62.0 bits (149), Expect = 2e-10
 Identities = 29/95 (30%), Positives = 58/95 (61%), Gaps = 1/95 (1%)

Query: 39  RQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGW 98
           ++G ++ V   +  +++ L T    G  ALH A L+G  E V+ LV YGA+++ + + G+
Sbjct: 54  KEGHVKMVVELLH-KEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGF 112

Query: 99  TPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           TPL++A  + + ++ ++L+  GA+++   +DG  P
Sbjct: 113 TPLYMAAQENHLEVVKFLLENGANQNVATEDGFTP 147



 Score = 53.5 bits (127), Expect = 7e-08
 Identities = 25/70 (35%), Positives = 40/70 (57%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G   LH A   GN++ VK L+++ AD++ + + G++PLH A   G+ DI   L+  GA  
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASP 760

Query: 124 DATNDDGDLP 133
           +  + DG  P
Sbjct: 761 NEVSSDGTTP 770



 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 32/86 (37%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +GL  LH AV   NL+ VKLL+  G   H     G+TPLHIA      ++AR L+  G  
Sbjct: 568 NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGS 627

Query: 123 RDATNDDGDLPSDLIDPD-YKELVEL 147
            +A +  G  P  L   + + E+V L
Sbjct: 628 ANAESVQGVTPLHLAAQEGHAEMVAL 653



 Score = 47.4 bits (111), Expect = 5e-06
 Identities = 30/94 (31%), Positives = 41/94 (43%)

Query: 40  QGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWT 99
           QGD     R +      +  I    L  LH A   G+    K+L+  GA  + R   G+T
Sbjct: 314 QGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFT 373

Query: 100 PLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           PLHIAC   +  +   L+  GA  DA  + G  P
Sbjct: 374 PLHIACKKNHVRVMELLLKTGASIDAVTESGLTP 407



 Score = 46.6 bits (109), Expect = 8e-06
 Identities = 24/71 (33%), Positives = 41/71 (57%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +GL+ +H A    +L+CV+LL++Y A+I        TPLH+A   G+  +A+ L+  GA 
Sbjct: 304 NGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAK 363

Query: 123 RDATNDDGDLP 133
            ++   +G  P
Sbjct: 364 PNSRALNGFTP 374



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 27/78 (34%), Positives = 41/78 (52%)

Query: 56  SLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARY 115
           S+  +  SGL  LH A   G+L  VK L++ GA  +  +    TPLH+A   G+ ++A+Y
Sbjct: 396 SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKY 455

Query: 116 LISLGADRDATNDDGDLP 133
           L+   A  +A   D   P
Sbjct: 456 LLQNKAKVNAKAKDDQTP 473



 Score = 45.1 bits (105), Expect = 2e-05
 Identities = 28/88 (31%), Positives = 43/88 (48%)

Query: 46  VGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIAC 105
           V + +  R  S+     +G+  LH A   GN+  V+LL+  GA I  + +   TPLH A 
Sbjct: 221 VAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAA 280

Query: 106 SDGYPDIARYLISLGADRDATNDDGDLP 133
            +G+  I+  L+  GA   A   +G  P
Sbjct: 281 RNGHVRISEILLDHGAPIQAKTKNGLSP 308



 Score = 44.3 bits (103), Expect = 4e-05
 Identities = 24/71 (33%), Positives = 38/71 (53%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A    ++  ++LL+K GA I    E+G TPLH+A   G+  I + L+  GA 
Sbjct: 370 NGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS 429

Query: 123 RDATNDDGDLP 133
            + +N   + P
Sbjct: 430 PNVSNVKVETP 440



 Score = 44.3 bits (103), Expect = 4e-05
 Identities = 22/75 (29%), Positives = 37/75 (49%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A     +E  + L++YG   +     G TPLH+A  +G+ ++   L+S  A+
Sbjct: 601 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 660

Query: 123 RDATNDDGDLPSDLI 137
            +  N  G  P  L+
Sbjct: 661 GNLGNKSGLTPLHLV 675



 Score = 43.5 bits (101), Expect = 7e-05
 Identities = 25/70 (35%), Positives = 37/70 (52%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G+  LH A   G+ E V LL+   A+ +  +++G TPLH+   +G+  +A  LI  G   
Sbjct: 635 GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMV 694

Query: 124 DATNDDGDLP 133
           DAT   G  P
Sbjct: 695 DATTRMGYTP 704



 Score = 43.1 bits (100), Expect = 9e-05
 Identities = 30/100 (30%), Positives = 50/100 (50%), Gaps = 1/100 (1%)

Query: 34  FLDHIRQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQR 93
           FL   R G+L++    +R   V + T + +GL  LH A   G+++ V  L+     +   
Sbjct: 16  FLRAARSGNLDKALDHLRNG-VDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETT 74

Query: 94  DEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
            + G T LHIA   G  ++ R L++ GA+ +A +  G  P
Sbjct: 75  TKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTP 114



 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 22/71 (30%), Positives = 35/71 (49%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           SGL  LH     G++    +L+K+G  +      G+TPLH+A   G   + ++L+   AD
Sbjct: 667 SGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQAD 726

Query: 123 RDATNDDGDLP 133
            +A    G  P
Sbjct: 727 VNAKTKLGYSP 737



 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 20/57 (35%), Positives = 33/57 (57%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLG 120
           G   L+ A    +LE VK L++ GA+ +   E G+TPL +A   G+ ++  +LI+ G
Sbjct: 111 GFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG 167



 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 39  RQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGW 98
           R+G++  V R +  R   + T     L  LH A  +G++   ++L+ +GA I  + + G 
Sbjct: 248 RRGNVIMV-RLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGL 306

Query: 99  TPLHIACSDGYPDIARYLISLGADRD 124
           +P+H+A    + D  R L+   A+ D
Sbjct: 307 SPIHMAAQGDHLDCVRLLLQYDAEID 332



 Score = 39.3 bits (90), Expect = 0.001
 Identities = 23/67 (34%), Positives = 32/67 (47%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A    NL   +LL+  GA ++   + G TPLHIA   G   + R L+  GA 
Sbjct: 205 TGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQ 264

Query: 123 RDATNDD 129
            +    D
Sbjct: 265 IETKTKD 271



 Score = 38.1 bits (87), Expect = 0.003
 Identities = 24/89 (26%), Positives = 39/89 (43%)

Query: 45  QVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIA 104
           +V +++   K  +          LH A   G+   VKLL++  A+ +    AG TPLHIA
Sbjct: 451 EVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIA 510

Query: 105 CSDGYPDIARYLISLGADRDATNDDGDLP 133
             +G+ +    L+   A +      G  P
Sbjct: 511 AREGHVETVLALLEKEASQACMTKKGFTP 539



 Score = 37.7 bits (86), Expect = 0.004
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 1/95 (1%)

Query: 39  RQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGW 98
           R+G +E V   +  ++ S A +   G   LH A   G +   +LL++  A  +   + G 
Sbjct: 512 REGHVETVLALLE-KEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGL 570

Query: 99  TPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           TPLH+A      DI + L+  G    +   +G  P
Sbjct: 571 TPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTP 605



 Score = 35.8 bits (81), Expect = 0.015
 Identities = 22/71 (30%), Positives = 34/71 (47%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A   G++E V  L++  A      + G+TPLH+A   G   +A  L+   A 
Sbjct: 502 AGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAH 561

Query: 123 RDATNDDGDLP 133
            +A   +G  P
Sbjct: 562 PNAAGKNGLTP 572



 Score = 35.4 bits (80), Expect = 0.019
 Identities = 20/53 (37%), Positives = 28/53 (52%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYL 116
           G + LH+A   G+ + V LL+K GA  ++    G TPL IA   GY  +   L
Sbjct: 734 GYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786



 Score = 34.7 bits (78), Expect = 0.033
 Identities = 18/66 (27%), Positives = 33/66 (50%)

Query: 68  LHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATN 127
           LH A  +G+ E  K L++  A ++ + +   TPLH A   G+ ++ + L+   A+ +   
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 500

Query: 128 DDGDLP 133
             G  P
Sbjct: 501 TAGHTP 506



 Score = 32.7 bits (73), Expect = 0.13
 Identities = 20/69 (28%), Positives = 35/69 (50%)

Query: 65  LAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRD 124
           L ALH A  + +     +L++   +     + G+TPLHIA      ++A+ L++ GA  +
Sbjct: 174 LPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVN 233

Query: 125 ATNDDGDLP 133
            T  +G  P
Sbjct: 234 FTPQNGITP 242


>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
          Length = 1856

 Score = 62.0 bits (149), Expect = 2e-10
 Identities = 29/95 (30%), Positives = 58/95 (61%), Gaps = 1/95 (1%)

Query: 39  RQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGW 98
           ++G ++ V   +  +++ L T    G  ALH A L+G  E V+ LV YGA+++ + + G+
Sbjct: 54  KEGHVKMVVELLH-KEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGF 112

Query: 99  TPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           TPL++A  + + ++ ++L+  GA+++   +DG  P
Sbjct: 113 TPLYMAAQENHLEVVKFLLENGANQNVATEDGFTP 147



 Score = 53.5 bits (127), Expect = 7e-08
 Identities = 25/70 (35%), Positives = 40/70 (57%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G   LH A   GN++ VK L+++ AD++ + + G++PLH A   G+ DI   L+  GA  
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASP 760

Query: 124 DATNDDGDLP 133
           +  + DG  P
Sbjct: 761 NEVSSDGTTP 770



 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 32/86 (37%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +GL  LH AV   NL+ VKLL+  G   H     G+TPLHIA      ++AR L+  G  
Sbjct: 568 NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGS 627

Query: 123 RDATNDDGDLPSDLIDPD-YKELVEL 147
            +A +  G  P  L   + + E+V L
Sbjct: 628 ANAESVQGVTPLHLAAQEGHAEMVAL 653



 Score = 47.4 bits (111), Expect = 5e-06
 Identities = 30/94 (31%), Positives = 41/94 (43%)

Query: 40  QGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWT 99
           QGD     R +      +  I    L  LH A   G+    K+L+  GA  + R   G+T
Sbjct: 314 QGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFT 373

Query: 100 PLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           PLHIAC   +  +   L+  GA  DA  + G  P
Sbjct: 374 PLHIACKKNHVRVMELLLKTGASIDAVTESGLTP 407



 Score = 46.6 bits (109), Expect = 8e-06
 Identities = 24/71 (33%), Positives = 41/71 (57%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +GL+ +H A    +L+CV+LL++Y A+I        TPLH+A   G+  +A+ L+  GA 
Sbjct: 304 NGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAK 363

Query: 123 RDATNDDGDLP 133
            ++   +G  P
Sbjct: 364 PNSRALNGFTP 374



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 27/78 (34%), Positives = 41/78 (52%)

Query: 56  SLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARY 115
           S+  +  SGL  LH A   G+L  VK L++ GA  +  +    TPLH+A   G+ ++A+Y
Sbjct: 396 SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKY 455

Query: 116 LISLGADRDATNDDGDLP 133
           L+   A  +A   D   P
Sbjct: 456 LLQNKAKVNAKAKDDQTP 473



 Score = 45.1 bits (105), Expect = 2e-05
 Identities = 28/88 (31%), Positives = 43/88 (48%)

Query: 46  VGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIAC 105
           V + +  R  S+     +G+  LH A   GN+  V+LL+  GA I  + +   TPLH A 
Sbjct: 221 VAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAA 280

Query: 106 SDGYPDIARYLISLGADRDATNDDGDLP 133
            +G+  I+  L+  GA   A   +G  P
Sbjct: 281 RNGHVRISEILLDHGAPIQAKTKNGLSP 308



 Score = 44.3 bits (103), Expect = 4e-05
 Identities = 24/71 (33%), Positives = 38/71 (53%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A    ++  ++LL+K GA I    E+G TPLH+A   G+  I + L+  GA 
Sbjct: 370 NGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS 429

Query: 123 RDATNDDGDLP 133
            + +N   + P
Sbjct: 430 PNVSNVKVETP 440



 Score = 44.3 bits (103), Expect = 4e-05
 Identities = 22/75 (29%), Positives = 37/75 (49%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A     +E  + L++YG   +     G TPLH+A  +G+ ++   L+S  A+
Sbjct: 601 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN 660

Query: 123 RDATNDDGDLPSDLI 137
            +  N  G  P  L+
Sbjct: 661 GNLGNKSGLTPLHLV 675



 Score = 43.5 bits (101), Expect = 7e-05
 Identities = 25/70 (35%), Positives = 37/70 (52%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           G+  LH A   G+ E V LL+   A+ +  +++G TPLH+   +G+  +A  LI  G   
Sbjct: 635 GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMV 694

Query: 124 DATNDDGDLP 133
           DAT   G  P
Sbjct: 695 DATTRMGYTP 704



 Score = 43.1 bits (100), Expect = 9e-05
 Identities = 30/100 (30%), Positives = 50/100 (50%), Gaps = 1/100 (1%)

Query: 34  FLDHIRQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQR 93
           FL   R G+L++    +R   V + T + +GL  LH A   G+++ V  L+     +   
Sbjct: 16  FLRAARSGNLDKALDHLRNG-VDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETT 74

Query: 94  DEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
            + G T LHIA   G  ++ R L++ GA+ +A +  G  P
Sbjct: 75  TKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTP 114



 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 22/71 (30%), Positives = 35/71 (49%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           SGL  LH     G++    +L+K+G  +      G+TPLH+A   G   + ++L+   AD
Sbjct: 667 SGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQAD 726

Query: 123 RDATNDDGDLP 133
            +A    G  P
Sbjct: 727 VNAKTKLGYSP 737



 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 20/57 (35%), Positives = 33/57 (57%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLG 120
           G   L+ A    +LE VK L++ GA+ +   E G+TPL +A   G+ ++  +LI+ G
Sbjct: 111 GFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG 167



 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 39  RQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGW 98
           R+G++  V R +  R   + T     L  LH A  +G++   ++L+ +GA I  + + G 
Sbjct: 248 RRGNVIMV-RLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGL 306

Query: 99  TPLHIACSDGYPDIARYLISLGADRD 124
           +P+H+A    + D  R L+   A+ D
Sbjct: 307 SPIHMAAQGDHLDCVRLLLQYDAEID 332



 Score = 39.3 bits (90), Expect = 0.001
 Identities = 23/67 (34%), Positives = 32/67 (47%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A    NL   +LL+  GA ++   + G TPLHIA   G   + R L+  GA 
Sbjct: 205 TGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQ 264

Query: 123 RDATNDD 129
            +    D
Sbjct: 265 IETKTKD 271



 Score = 38.1 bits (87), Expect = 0.003
 Identities = 24/89 (26%), Positives = 39/89 (43%)

Query: 45  QVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIA 104
           +V +++   K  +          LH A   G+   VKLL++  A+ +    AG TPLHIA
Sbjct: 451 EVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIA 510

Query: 105 CSDGYPDIARYLISLGADRDATNDDGDLP 133
             +G+ +    L+   A +      G  P
Sbjct: 511 AREGHVETVLALLEKEASQACMTKKGFTP 539



 Score = 37.7 bits (86), Expect = 0.004
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 1/95 (1%)

Query: 39  RQGDLEQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGW 98
           R+G +E V   +  ++ S A +   G   LH A   G +   +LL++  A  +   + G 
Sbjct: 512 REGHVETVLALLE-KEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGL 570

Query: 99  TPLHIACSDGYPDIARYLISLGADRDATNDDGDLP 133
           TPLH+A      DI + L+  G    +   +G  P
Sbjct: 571 TPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTP 605



 Score = 35.8 bits (81), Expect = 0.015
 Identities = 22/71 (30%), Positives = 34/71 (47%)

Query: 63  SGLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           +G   LH A   G++E V  L++  A      + G+TPLH+A   G   +A  L+   A 
Sbjct: 502 AGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAH 561

Query: 123 RDATNDDGDLP 133
            +A   +G  P
Sbjct: 562 PNAAGKNGLTP 572



 Score = 35.4 bits (80), Expect = 0.019
 Identities = 20/53 (37%), Positives = 28/53 (52%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYL 116
           G + LH+A   G+ + V LL+K GA  ++    G TPL IA   GY  +   L
Sbjct: 734 GYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786



 Score = 34.7 bits (78), Expect = 0.033
 Identities = 18/66 (27%), Positives = 33/66 (50%)

Query: 68  LHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATN 127
           LH A  +G+ E  K L++  A ++ + +   TPLH A   G+ ++ + L+   A+ +   
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 500

Query: 128 DDGDLP 133
             G  P
Sbjct: 501 TAGHTP 506



 Score = 32.7 bits (73), Expect = 0.13
 Identities = 20/69 (28%), Positives = 35/69 (50%)

Query: 65  LAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRD 124
           L ALH A  + +     +L++   +     + G+TPLHIA      ++A+ L++ GA  +
Sbjct: 174 LPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVN 233

Query: 125 ATNDDGDLP 133
            T  +G  P
Sbjct: 234 FTPQNGITP 242


>gi|7705748 TNNI3 interacting kinase isoform b [Homo sapiens]
          Length = 835

 Score = 62.0 bits (149), Expect = 2e-10
 Identities = 29/73 (39%), Positives = 47/73 (64%)

Query: 64  GLAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADR 123
           GL ALH A ++G+LE   +L+++GA+++ +D   +TPLHIA   G+  + R L+  GAD 
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193

Query: 124 DATNDDGDLPSDL 136
           + + + GD P  L
Sbjct: 194 NVSGEVGDRPLHL 206



 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 23/64 (35%), Positives = 38/64 (59%)

Query: 68  LHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATN 127
           LH A   G+ +  +LL+K+GAD++   E G  PLH+A + G+ +IA+ L+  G+  D   
Sbjct: 171 LHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNA 230

Query: 128 DDGD 131
            D +
Sbjct: 231 QDNE 234



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 4/97 (4%)

Query: 44  EQVGRFIRTRKVSLATIHPSGLAALHEAVLSGNLECVKLLVKYG--ADIHQRDEAGWTPL 101
           EQV R +      +      G   LH A   G L   KLL++ G  AD++ +D     PL
Sbjct: 180 EQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPL 239

Query: 102 HIACSDGYPDIARYLI--SLGADRDATNDDGDLPSDL 136
           H     G+ DI +YL+   L       N  GD P  L
Sbjct: 240 HFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHL 276



 Score = 32.3 bits (72), Expect = 0.16
 Identities = 18/64 (28%), Positives = 34/64 (53%), Gaps = 2/64 (3%)

Query: 68  LHEAVLSGNLECVKLLVKYGADI--HQRDEAGWTPLHIACSDGYPDIARYLISLGADRDA 125
           LH     G+ + VK L++   ++  H  +  G TPLH+AC +G  ++A+ +I +      
Sbjct: 239 LHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESL 298

Query: 126 TNDD 129
           T ++
Sbjct: 299 TKEN 302



 Score = 31.2 bits (69), Expect = 0.37
 Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 2/58 (3%)

Query: 67  ALHEAVLSG-NLECVKLLVKYGA-DIHQRDEAGWTPLHIACSDGYPDIARYLISLGAD 122
           A H A   G +++ VK L+     +I+ +   G T LH AC  G+  + ++L+  GAD
Sbjct: 308 AFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGAD 365


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,747,454
Number of Sequences: 37866
Number of extensions: 238371
Number of successful extensions: 2380
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 361
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 518
Number of HSP's gapped (non-prelim): 1646
length of query: 154
length of database: 18,247,518
effective HSP length: 93
effective length of query: 61
effective length of database: 14,725,980
effective search space: 898284780
effective search space used: 898284780
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.