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Search of human proteins with 134268640
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|134268640 tectorin alpha precursor [Homo sapiens]
(2155 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|134268640 tectorin alpha precursor [Homo sapiens] 4571 0.0
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens] 858 0.0
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ... 848 0.0
gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr... 731 0.0
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 654 0.0
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 638 0.0
gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr... 560 e-159
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom... 300 1e-80
gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom... 300 1e-80
gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap... 300 1e-80
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 270 1e-71
gi|122937283 6720455I24Rik homolog [Homo sapiens] 270 1e-71
gi|116284392 mucin 2 precursor [Homo sapiens] 268 4e-71
gi|239757284 PREDICTED: similar to Fc fragment of IgG binding pr... 247 8e-65
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] 237 8e-62
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens] 237 8e-62
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens] 237 8e-62
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens] 237 8e-62
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens] 237 8e-62
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens] 237 8e-62
gi|161019170 mucin 5AC [Homo sapiens] 236 2e-61
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 236 2e-61
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens] 231 6e-60
gi|56550049 uromodulin precursor [Homo sapiens] 214 6e-55
gi|59850812 uromodulin precursor [Homo sapiens] 214 6e-55
gi|134031945 SCO-spondin [Homo sapiens] 210 1e-53
gi|119220571 zymogen granule membrane glycoprotein 2 isoform 2 [... 206 2e-52
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 206 3e-52
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 206 3e-52
gi|119220569 zymogen granule membrane glycoprotein 2 isoform 1 [... 205 4e-52
>gi|134268640 tectorin alpha precursor [Homo sapiens]
Length = 2155
Score = 4571 bits (11857), Expect = 0.0
Identities = 2155/2155 (100%), Positives = 2155/2155 (100%)
Query: 1 MNYSSFLRIWVSFIFALVQHQAQPRELMYPFWQNDTKTPKVDDGSSSEIKLAIPVFFFGV 60
MNYSSFLRIWVSFIFALVQHQAQPRELMYPFWQNDTKTPKVDDGSSSEIKLAIPVFFFGV
Sbjct: 1 MNYSSFLRIWVSFIFALVQHQAQPRELMYPFWQNDTKTPKVDDGSSSEIKLAIPVFFFGV 60
Query: 61 PYRTVYVNNNGVVSFNVLVSQFTPESFPLTDGRAFVAPFWADVHNGIRGEIYYRETMEPA 120
PYRTVYVNNNGVVSFNVLVSQFTPESFPLTDGRAFVAPFWADVHNGIRGEIYYRETMEPA
Sbjct: 61 PYRTVYVNNNGVVSFNVLVSQFTPESFPLTDGRAFVAPFWADVHNGIRGEIYYRETMEPA 120
Query: 121 ILKRATKDIRKYFKDMATFSATWVFIVTWEEVTFYGGSSTTPVNTFQAVLVSDGSYTFTL 180
ILKRATKDIRKYFKDMATFSATWVFIVTWEEVTFYGGSSTTPVNTFQAVLVSDGSYTFTL
Sbjct: 121 ILKRATKDIRKYFKDMATFSATWVFIVTWEEVTFYGGSSTTPVNTFQAVLVSDGSYTFTL 180
Query: 181 FNYYEINWTTGTASGGDPLTGLGGVMAQAGFNGGNLTNFFSLPGSRTPEIVNIQETTNVN 240
FNYYEINWTTGTASGGDPLTGLGGVMAQAGFNGGNLTNFFSLPGSRTPEIVNIQETTNVN
Sbjct: 181 FNYYEINWTTGTASGGDPLTGLGGVMAQAGFNGGNLTNFFSLPGSRTPEIVNIQETTNVN 240
Query: 241 VPGRWAFKVDGKEIDPANGCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCS 300
VPGRWAFKVDGKEIDPANGCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCS
Sbjct: 241 VPGRWAFKVDGKEIDPANGCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCS 300
Query: 301 PYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPF 360
PYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPF
Sbjct: 301 PYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPF 360
Query: 361 FSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKI 420
FSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKI
Sbjct: 361 FSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKI 420
Query: 421 YQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPA 480
YQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPA
Sbjct: 421 YQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPA 480
Query: 481 MSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTV 540
MSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTV
Sbjct: 481 MSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTV 540
Query: 541 VDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSF 600
VDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSF
Sbjct: 541 VDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSF 600
Query: 601 SHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYT 660
SHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYT
Sbjct: 601 SHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYT 660
Query: 661 MGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQV 720
MGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQV
Sbjct: 661 MGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQV 720
Query: 721 LHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKI 780
LHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKI
Sbjct: 721 LHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKI 780
Query: 781 GGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTT 840
GGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTT
Sbjct: 781 GGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTT 840
Query: 841 YFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDS 900
YFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDS
Sbjct: 841 YFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDS 900
Query: 901 ELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARY 960
ELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARY
Sbjct: 901 ELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARY 960
Query: 961 ASACKNADVEVGPWRTYDFCPLECPENSHFEECITCTETCETLTLGPICVDSCSEGCQCD 1020
ASACKNADVEVGPWRTYDFCPLECPENSHFEECITCTETCETLTLGPICVDSCSEGCQCD
Sbjct: 961 ASACKNADVEVGPWRTYDFCPLECPENSHFEECITCTETCETLTLGPICVDSCSEGCQCD 1020
Query: 1021 EGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDD 1080
EGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDD
Sbjct: 1021 EGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDD 1080
Query: 1081 EYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPK 1140
EYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPK
Sbjct: 1081 EYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPK 1140
Query: 1141 FVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINI 1200
FVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINI
Sbjct: 1141 FVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINI 1200
Query: 1201 FSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLA 1260
FSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLA
Sbjct: 1201 FSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLA 1260
Query: 1261 SSVNEFGQSWVKRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNP 1320
SSVNEFGQSWVKRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNP
Sbjct: 1261 SSVNEFGQSWVKRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNP 1320
Query: 1321 TFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYES 1380
TFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYES
Sbjct: 1321 TFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYES 1380
Query: 1381 CVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLF 1440
CVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLF
Sbjct: 1381 CVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLF 1440
Query: 1441 WNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDG 1500
WNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDG
Sbjct: 1441 WNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDG 1500
Query: 1501 AFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRN 1560
AFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRN
Sbjct: 1501 AFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRN 1560
Query: 1561 TVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCG 1620
TVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCG
Sbjct: 1561 TVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCG 1620
Query: 1621 LCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNV 1680
LCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNV
Sbjct: 1621 LCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNV 1680
Query: 1681 HIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQLCGSLAAYGEA 1740
HIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQLCGSLAAYGEA
Sbjct: 1681 HIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQLCGSLAAYGEA 1740
Query: 1741 CRSFGILSTEWIEKENCSGVVEDPCVGADCPNRTCELGNGRELCGCIEPPPYGNNSHDII 1800
CRSFGILSTEWIEKENCSGVVEDPCVGADCPNRTCELGNGRELCGCIEPPPYGNNSHDII
Sbjct: 1741 CRSFGILSTEWIEKENCSGVVEDPCVGADCPNRTCELGNGRELCGCIEPPPYGNNSHDII 1800
Query: 1801 DAEVTCKAAQMEVSISKCKLFQLGFEREGVRINDRQCTGIEGEDFISFQINNTKGNCGNI 1860
DAEVTCKAAQMEVSISKCKLFQLGFEREGVRINDRQCTGIEGEDFISFQINNTKGNCGNI
Sbjct: 1801 DAEVTCKAAQMEVSISKCKLFQLGFEREGVRINDRQCTGIEGEDFISFQINNTKGNCGNI 1860
Query: 1861 VQSNGTHIMYKNTLWIESANNTGNIITRDRTINVEFSCAYELDIKISLDSVVKPMLSVIN 1920
VQSNGTHIMYKNTLWIESANNTGNIITRDRTINVEFSCAYELDIKISLDSVVKPMLSVIN
Sbjct: 1861 VQSNGTHIMYKNTLWIESANNTGNIITRDRTINVEFSCAYELDIKISLDSVVKPMLSVIN 1920
Query: 1921 LTVPTQEGSFITKMALYKNASYKHPYRQGEVVLTTRDVLYVGVFVVGADATHLILTLNKC 1980
LTVPTQEGSFITKMALYKNASYKHPYRQGEVVLTTRDVLYVGVFVVGADATHLILTLNKC
Sbjct: 1921 LTVPTQEGSFITKMALYKNASYKHPYRQGEVVLTTRDVLYVGVFVVGADATHLILTLNKC 1980
Query: 1981 YATPTRDSNDKLRYFIIEGGCQNLKDNTIGIEENAVSLTCRFHVTVFKFIGDYDEVHLHC 2040
YATPTRDSNDKLRYFIIEGGCQNLKDNTIGIEENAVSLTCRFHVTVFKFIGDYDEVHLHC
Sbjct: 1981 YATPTRDSNDKLRYFIIEGGCQNLKDNTIGIEENAVSLTCRFHVTVFKFIGDYDEVHLHC 2040
Query: 2041 AVSLCDSEKYSCKITCPHNSRIATDYTKEPKEQIISVGPIRRKRLDWCEDNGGCEQICTS 2100
AVSLCDSEKYSCKITCPHNSRIATDYTKEPKEQIISVGPIRRKRLDWCEDNGGCEQICTS
Sbjct: 2041 AVSLCDSEKYSCKITCPHNSRIATDYTKEPKEQIISVGPIRRKRLDWCEDNGGCEQICTS 2100
Query: 2101 RVDGPLCSCVTGTLQEDGKSCRASNSSMELQVWTLLLIMIQISLWHFVYKSGTTS 2155
RVDGPLCSCVTGTLQEDGKSCRASNSSMELQVWTLLLIMIQISLWHFVYKSGTTS
Sbjct: 2101 RVDGPLCSCVTGTLQEDGKSCRASNSSMELQVWTLLLIMIQISLWHFVYKSGTTS 2155
>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
Length = 5405
Score = 858 bits (2218), Expect = 0.0
Identities = 512/1620 (31%), Positives = 751/1620 (46%), Gaps = 99/1620 (6%)
Query: 239 VNVPGRWAFKVDGKEIDPAN--GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQE 296
V +PG F G PA+ GCT +G L G+ W D C +C C +++ C++
Sbjct: 781 VCLPG---FVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 837
Query: 297 -ASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQT 355
SC E C + C TC G+PHY +FDG F F G+C YLL C Q
Sbjct: 838 KQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQN 897
Query: 356 SSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDL 415
++LP F V +NEHR VS+ + + VE G K+ + + G+V V+D++ LP
Sbjct: 898 AALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAAD 957
Query: 416 GTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRP 475
G V++++ G V TDFGL VT+D + VP SY + CGLCGN+N +P DD
Sbjct: 958 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
Query: 476 DGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLW 535
G A + L G SW+ C + +C + D+ + CG L GP
Sbjct: 1018 GGGQAANALAFGNSWQ-EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFR 1076
Query: 536 ECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTV 595
EC + +DP V CVYD C + LC A+ YA CQA G + WR++ C +
Sbjct: 1077 ECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELC--PL 1134
Query: 596 QCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFD 655
CP SHY C+ CP +C DL C + C EGC C++GF LS C+PL CGC
Sbjct: 1135 SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQ 1194
Query: 656 GHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLL 715
G Y+ G+ F+ C C C+EGG V C + +CG E C G GC + C
Sbjct: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQA 1254
Query: 716 SQNQVLHTFDGASYAFPSEFSYTLLKTCPERP---EYLEIDINKKKPDAGPAWLRGLRIL 772
S + TFDG + F Y L +TC RP + + N + + R + +
Sbjct: 1255 SGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQ 1314
Query: 773 VADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGL 832
VA+ +++ +V +NG +++LP +G++ ++ + +E+ + V Y +
Sbjct: 1315 VANFTLRLEQ-RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYY 1373
Query: 833 LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEI-------- 884
+ + + Y+ GLCG YN + D+F PNG N F SW EE+
Sbjct: 1374 VRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSW---EEVVPDSPCLP 1430
Query: 885 ---CNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLF 941
C D + + EL K Y+ CG+++ P+ CH +V+ + C+F
Sbjct: 1431 PTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPT-GPLSSCHKLVDPQGPLKDCIF 1489
Query: 942 RLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECI-TCTETC 1000
LC GGN S LC ++ Y SAC+ A V PWRT FCP+ECP NSH+E C TC+ C
Sbjct: 1490 DLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC 1549
Query: 1001 ETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIF 1060
L+ P C D C+EGCQCD G+ G CV +CGC G +T +D +C+
Sbjct: 1550 SALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLID-NCRQQ 1608
Query: 1061 CYCSGTDNRV-------------------------HCETIPCKDDEYCMEEGGLYYCQAR 1095
C C V C + C+ E C E+GG C
Sbjct: 1609 CTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPN 1668
Query: 1096 TDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTG-SRPSSDSFPKFVVTAKNEDRDPSL 1154
+A+C + G HY +FDG FDFQ +C +L TTG S+ F VT KN++R
Sbjct: 1669 YEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPA 1728
Query: 1155 ALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFG 1214
+V+ V V G +I IH+ V VN LP+ + G+I++ ++ DFG
Sbjct: 1729 VSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFG 1788
Query: 1215 LKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKR- 1273
L+V YDW + +T+P S + GLCG + NP++D P G LA S+ +G SW
Sbjct: 1789 LQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPG 1848
Query: 1274 -DTFCQVGCGDRCPSCA--KVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFD 1330
D C C CP+C ++E + L P F+ CH+ V P F+K C+ D
Sbjct: 1849 WDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLD 1908
Query: 1331 SCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRC- 1389
C+ GG C L +Y + CQ G+ + WR C +TCP NSHYE C S C C
Sbjct: 1909 VCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCP 1968
Query: 1390 --AAIRLKSDCSHYCVEGCHCDAGYVLNGKSCI-LPHSCGCYSDGKYYEPKQLFW-NSDC 1445
A + + C CVEGC CDAG+VL+ C+ L + CGC+++G Y+E FW + C
Sbjct: 1969 SPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTC 2028
Query: 1446 TRRCRCF-RRNVIQCDPRQCKSDEECA-LRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFL 1503
++ CRC + C P C E C L +G GC T+ C A G + T DG
Sbjct: 2029 SQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRF 2088
Query: 1504 RFPANCAFVLSTICQKLP--DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDR-- 1559
F C ++LS C P +F + + + + ++ V I + ++ R
Sbjct: 2089 NFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWP 2148
Query: 1560 NTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVC 1619
++V+G V +PF + S +V+ T+ + + ++G + +++ + +C
Sbjct: 2149 RKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLC 2208
Query: 1620 GLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDN 1679
GLCGN+N D DD + GKP W+ G Q C E + C
Sbjct: 2209 GLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQ------GCGECVSKPCPSPCTP 2254
Query: 1680 VHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGC-YSHKKFQLCGSLAAYG 1738
+ G C ++ G PC+GL+ P +++ C LD C LC ++A Y
Sbjct: 2255 EQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYV 2314
Query: 1739 EACRSFGILSTEWIEKENCS---------GVVEDPCVGADCPNRTCELG---NGRELCGC 1786
AC++ G EW + C + D C G+ CP+ + G RE C C
Sbjct: 2315 AACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGS-CPSLSAPEGCESACREGCVC 2373
Score = 850 bits (2197), Expect = 0.0
Identities = 506/1557 (32%), Positives = 740/1557 (47%), Gaps = 109/1557 (7%)
Query: 294 CQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCL 353
C+ C+ + C+ G C A T+ C G+PHY TFDG + G+C+Y + C
Sbjct: 444 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 503
Query: 354 QTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTL 413
+ +LP FSVEAKNEHR VS+V ++V + + + +G G V V++ + LPV+L
Sbjct: 504 EDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSL 563
Query: 414 DLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFL 473
G +++YQSG VE FGL+VT+D ++S+P + + CGLCGNYN +P DDFL
Sbjct: 564 SEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 623
Query: 474 RPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGP 533
PDG A ++ SW++ D+ C+ GC +NC C Y G CG L K DGP
Sbjct: 624 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 683
Query: 534 LWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVS 593
C +DP F+ CVYDLC V LC+ + AYA C LGI +GDWR+ C
Sbjct: 684 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC-- 741
Query: 594 TVQCPSFSHYSVCTSSCPDTCSDLTASRNCA-TPCTEGCECNQGFVLSTSQCVPLHKCGC 652
+ CP+ S Y +C +CP +C+ A NC+ PC EGC C GFV S CVP CGC
Sbjct: 742 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801
Query: 653 DFDGHYYTMGEFFWATANCTVQCLCEEG-GDVYCFNK-TCGSGEVCAVEDGYQGCFPKRE 710
F G G+ WA C +C C V C +K +C +GE C+V++G GC+P R
Sbjct: 802 TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 861
Query: 711 TVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPER---PEYLEIDINKKKPDAGPAWLR 767
C S + +FDG + F +Y L+ +C + P + + N+ + ++ R
Sbjct: 862 GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTR 921
Query: 768 GLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQY 827
+R+ +V + +V ++ LPF G+++++R V + +TV Y
Sbjct: 922 AVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTY 981
Query: 828 SDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNG 887
+ ++ ++Y GLCG +N + +D+ L G N F SW EE G
Sbjct: 982 DWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ--EETRPG 1039
Query: 888 ----ECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRL 943
E GD K DS + + +S++ CGI+ DP F ECH ++ R C++
Sbjct: 1040 CGATEPGDCPKL---DSLVAQQLQSKNECGILADP-KGPFRECHSKLDPQGAVRDCVYDR 1095
Query: 944 CQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC-ITCTETCET 1002
C G LCD++A YA+AC+ A V PWR+ + CPL CP +SH+E C C +C
Sbjct: 1096 CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGD 1155
Query: 1003 LTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCY 1062
L + C C EGC CDEG+AL G C+ + CGC +G +TF+ C C+
Sbjct: 1156 LPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCH 1215
Query: 1063 CSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSC 1122
C V CE+ C E C GG C A ++C SG HY TFDG FDF +C
Sbjct: 1216 CQ-EGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC 1274
Query: 1123 PLILC-TTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVL 1181
+L T G+RP +F V +N + + V V +++ + + + V
Sbjct: 1275 VYVLAQTCGTRP---GLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQR-QWKVT 1330
Query: 1182 VNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLC 1241
VN + LP+ L G+I G VV+ETDFGL+V YD ++ +TVP + GLC
Sbjct: 1331 VNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLC 1390
Query: 1242 GRYNGNPDDDLEMPMGLLASSVNEFGQSWVK--------RDTFCQVGCGDRCPS--C-AK 1290
G YNG+P DD + P G A + NEFG SW + T C G D PS C +
Sbjct: 1391 GNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPE 1450
Query: 1291 VEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYAS 1350
+E + ++ C L+ + S CH V+P K+C+FD C+ GG + CS + Y S
Sbjct: 1451 LEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVS 1510
Query: 1351 TCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDA 1410
CQ G V WR T C + CPPNSHYE C C C+A+ C C EGC CD+
Sbjct: 1511 ACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDS 1570
Query: 1411 GYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEEC 1470
G++ NG++C+ CGCY +G YYEP+Q +C ++C C + C CK + C
Sbjct: 1571 GFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVC 1630
Query: 1471 ALRNGVRGCFSTKTSY---------CLAAGG-GV----------------FRTFDGAFLR 1504
G+ C + + C GG GV + +FDG
Sbjct: 1631 QPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 1690
Query: 1505 FPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRN---- 1560
F C +VL+T P +S Q + F + N +P Y+ + N
Sbjct: 1691 FQGTCNYVLAT--TGCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVVTVAALGTNISIH 1747
Query: 1561 -----TVKVNGTQVNVPFITG---LATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISE 1612
V+VNG +P ++ +S+ LV D +Q+ Y+ + +++
Sbjct: 1748 KDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFG--LQVSYDWNWRVDVTLPS 1805
Query: 1613 RLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGM------QKRPLAPSCN 1666
VCGLCGN + + +D V G S + SW+ G + R P+C
Sbjct: 1806 SYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCP 1865
Query: 1667 ELQFSQYAAMCDNVHIQKMQGDGYCLKLT-DMKGFFQPCYGLLDPLPFYESCYLDGCY-S 1724
E + QY +G G+C L G F C+ + P F++ C LD C
Sbjct: 1866 EDRLEQY------------EGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGG 1913
Query: 1725 HKKFQLCGSLAAYGEACRSFGILSTEWIEKENCS---------GVVEDPCVGADCPN 1772
+ LC +LA+Y AC++ G++ +W + C V PC A CP+
Sbjct: 1914 GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPC-PASCPS 1969
Score = 798 bits (2061), Expect = 0.0
Identities = 510/1642 (31%), Positives = 747/1642 (45%), Gaps = 163/1642 (9%)
Query: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVE 318
GC G + + D NC +C C + CQE SC P +VC+P G C +
Sbjct: 2787 GCYHNGAYYEPEQTVLID-NCRQQCTC-HVGKVVVCQEHSCKPGQVCQPSGGILSCVNKD 2844
Query: 319 T--------------------------STCVVFGEPHYHTFDGFLFHFQGSCAYLLARQ- 351
+TC ++G+PHYH+FDG F FQG+C Y+LA
Sbjct: 2845 PCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 2904
Query: 352 C--LQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSL 409
C + T L F+V KN++R AVS+V+ ++V G I I K G+V+VN ++T+L
Sbjct: 2905 CPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 2964
Query: 410 PVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPL 469
PV++ G + + Q + DFGL V++D +++P SY + CGLCGN ++NP
Sbjct: 2965 PVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPN 3024
Query: 470 DDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNK 529
+D + P+G A S+ G SWR D C C +C C Y G +CG L
Sbjct: 3025 NDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAP 3084
Query: 530 -TDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQ 588
T GP C V P +F CV D+C + +LC+A+ +Y CQA G+ I DWR Q
Sbjct: 3085 GTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQ 3144
Query: 589 TGCVSTVQCPSFSHYSVCTSSCPDTC---SDLTASRNCATPCTEGCECNQGFVLSTSQCV 645
GC T CP SHY VC CP +C + LT C PC EGC+C+ GFVLS +CV
Sbjct: 3145 VGCEIT--CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCV 3202
Query: 646 PLHK-CGCDFDGHYYTMGEFFWATANCTVQCLCEEGG-DVYCFNKTCGSGEVCAV-EDGY 702
PL+ CGC +G Y+ G FWA C+ C C GG + C +CG GEVC + G
Sbjct: 3203 PLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQ 3262
Query: 703 QGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERP---EYLEIDI-NKKK 758
GC P C + T DG + F Y L C P E + + N+ +
Sbjct: 3263 HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHR 3322
Query: 759 PDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVE 818
++ R + + + + + + +++++G V LPF S L + + V
Sbjct: 3323 GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDS-LLHAHLSGADVVVT 3381
Query: 819 SKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESW 878
+ +++ + + +R+ Y GLCG YN + +D+ GK W
Sbjct: 3382 TTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA--------GW 3433
Query: 879 TTFEEICNGECGDLLKACNNDS--ELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYY 936
GEC + K C + E + + CG+I+ ++ CHG+V Y+
Sbjct: 3434 QVGGAQGCGEC--VSKPCPSPCTPEQQESFGGPDACGVIS-ATDGPLAPCHGLVPPAQYF 3490
Query: 937 RTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC-IT 995
+ CL CQ G+ LC +VA Y +AC+ A ++ WR DFCP +CP +SH+E C +
Sbjct: 3491 QGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDS 3550
Query: 996 CTETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDL 1055
C +C +L+ C +C EGC CD G+ L G CV +CGC + +TF+
Sbjct: 3551 CPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGP 3610
Query: 1056 DCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFP 1115
C C C V CE C E C GG C A +C SG HY TFDG
Sbjct: 3611 GCDSLCRCR-EGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHR 3669
Query: 1116 FDFQTSCPLILCTT-GSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHR 1174
FDF +C +L T G+RP +F V +N + + V V +++ + +
Sbjct: 3670 FDFMGTCVYVLAQTCGTRPG---LHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 3726
Query: 1175 AYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQ 1234
+ V VN + LP+ L G+I G VV+ETDFGL+V YD ++ +TVP +
Sbjct: 3727 R-QWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYY 3785
Query: 1235 NSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSW--VKRDTFC---------QVGC-- 1281
GLCG YNG+P DD + P G A + NEFG SW V D+ C GC
Sbjct: 3786 QLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIP 3845
Query: 1282 GDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTA 1341
D+CP ++E + ++ C L+ + S CH V+P K+C+FD C+ GG +
Sbjct: 3846 SDKCPP--ELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 3903
Query: 1342 CSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHY 1401
CS + Y S CQ G V WRN T C + CP NSHYE C C C+A+ C
Sbjct: 3904 CSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDG 3963
Query: 1402 CVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDP 1461
C EGC CD+G++ NG++C+ CGCY +G YYEP+Q +C ++C C V+ C
Sbjct: 3964 CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQE 4023
Query: 1462 RQCKSDEECALRNGVRGCFSTKTSY---------CLAAGG-GV----------------F 1495
CK + C G+ C + + C GG GV +
Sbjct: 4024 HSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHY 4083
Query: 1496 RTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQIL 1555
+FDG F C +VL+T P +S Q + F + N +P Y+ +
Sbjct: 4084 HSFDGRKFDFQGTCNYVLAT--TGCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVVTVA 4140
Query: 1556 INDRN---------TVKVNGTQVNVPFITG---LATKIYSSEGFLVIDTSPDIQIYYNGF 1603
N V+VNG +P ++ +S+ LV D +Q+ Y+
Sbjct: 4141 ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFG--LQVSYDWN 4198
Query: 1604 NVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGM------Q 1657
+ +++ VCGLCGN + + +D V G S + SW+ G +
Sbjct: 4199 WRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDE 4258
Query: 1658 KRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTD-MKGFFQPCYGLLDPLPFYES 1716
R P+C E + QY +G G+C L+ G F C+ + P F++
Sbjct: 4259 CRGSCPTCPEDRLEQY------------EGPGFCGPLSSGTGGPFTTCHAHVPPESFFKG 4306
Query: 1717 CYLDGCY-SHKKFQLCGSLAAYGEACRSFGILSTEWIEKENCSGVVEDPCVGADCPNRTC 1775
C LD C + LC +LA+Y AC++ G++ +W + C TC
Sbjct: 4307 CVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGC--------------EITC 4352
Query: 1776 ELGNGRELCG------CIEPPP 1791
+ E+CG C P P
Sbjct: 4353 PENSHYEVCGPPCPASCPSPAP 4374
Score = 795 bits (2054), Expect = 0.0
Identities = 510/1642 (31%), Positives = 746/1642 (45%), Gaps = 163/1642 (9%)
Query: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVE 318
GC G + + D NC +C C + CQE SC P +VC+P G C +
Sbjct: 1586 GCYHNGVYYEPEQTVLID-NCRQQCTC-HAGKGMVCQEHSCKPGQVCQPSGGILSCVTKD 1643
Query: 319 T--------------------------STCVVFGEPHYHTFDGFLFHFQGSCAYLLARQ- 351
+TC ++G+PHYH+FDG F FQG+C Y+LA
Sbjct: 1644 PCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 1703
Query: 352 C--LQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSL 409
C + T L F+V KN++R AVS+V+ ++V G I I K G+V+VN ++T+L
Sbjct: 1704 CPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 1763
Query: 410 PVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPL 469
PV++ G + + Q + DFGL V++D +++P SY + CGLCGN ++NP
Sbjct: 1764 PVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPN 1823
Query: 470 DDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNK 529
+D + P+G A S+ G SWR D C C +C C Y G +CG L
Sbjct: 1824 NDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAP 1883
Query: 530 -TDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQ 588
T GP C V P +F CV D+C + +LC+A+ +Y CQA G+ I DWR Q
Sbjct: 1884 GTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQ 1943
Query: 589 TGCVSTVQCPSFSHYSVCTSSCPDTC---SDLTASRNCATPCTEGCECNQGFVLSTSQCV 645
GC T CP SHY VC S CP +C + LT C PC EGC+C+ GFVLS +CV
Sbjct: 1944 VGCEIT--CPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCV 2001
Query: 646 PLHK-CGCDFDGHYYTMGEFFWATANCTVQCLCEEGG-DVYCFNKTCGSGEVCAV-EDGY 702
PL+ CGC +G Y+ G FWA C+ C C GG + C +CG GEVC + G
Sbjct: 2002 PLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQ 2061
Query: 703 QGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERP---EYLEIDI-NKKK 758
GC P C + T DG + F Y L C P E + + N+ +
Sbjct: 2062 HGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHR 2121
Query: 759 PDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVE 818
++ R + + + + + + +++++G V LPF S L + + V
Sbjct: 2122 GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDS-LLHAHLSGADVVVT 2180
Query: 819 SKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESW 878
+ +++ + + +R+ Y GLCG YN + +D+ GK W
Sbjct: 2181 TTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA--------GW 2232
Query: 879 TTFEEICNGECGDLLKACNNDS--ELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYY 936
GEC + K C + E + + CG+I+ ++ CHG+V Y+
Sbjct: 2233 QVGGAQGCGEC--VSKPCPSPCTPEQQESFGGPDACGVIS-ATDGPLAPCHGLVPPAQYF 2289
Query: 937 RTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC-IT 995
+ CL CQ G+ LC +VA Y +AC+ A ++ WR DFCP +CP +SH+E C +
Sbjct: 2290 QGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDS 2349
Query: 996 CTETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDL 1055
C +C +L+ C +C EGC CD G+ L G CV +CGC + +TF+
Sbjct: 2350 CPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGP 2409
Query: 1056 DCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFP 1115
C C C V CE C E C GG C A +C SG HY TFDG
Sbjct: 2410 GCDSLCRCR-EGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRR 2468
Query: 1116 FDFQTSCPLILCTT-GSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHR 1174
FDF +C +L T G+RP +F V +N + + V V +++ + +
Sbjct: 2469 FDFMGTCVYVLAQTCGTRPG---LHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 2525
Query: 1175 AYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQ 1234
+ V VN + LP+ L G+I G VV+ETDFGL+V YD ++ +TVP +
Sbjct: 2526 R-QWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYY 2584
Query: 1235 NSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSW--VKRDTFC---------QVGC-- 1281
GLCG YNG+P DD + P G A + NEFG SW V D+ C GC
Sbjct: 2585 QLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIP 2644
Query: 1282 GDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTA 1341
+ CP ++E + ++ C L+ + S CH V+P K+C+FD C+ GG +
Sbjct: 2645 SEECPP--ELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 2702
Query: 1342 CSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHY 1401
CS + Y S CQ G V WRN T C + CP NSHYE C C C+A+ C
Sbjct: 2703 CSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDG 2762
Query: 1402 CVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDP 1461
C EGC CD+G++ NG++C+ CGCY +G YYEP+Q +C ++C C V+ C
Sbjct: 2763 CAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQE 2822
Query: 1462 RQCKSDEECALRNGVRGCFSTKTSY---------CLAAGG-GV----------------F 1495
CK + C G+ C + + C GG GV +
Sbjct: 2823 HSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHY 2882
Query: 1496 RTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQIL 1555
+FDG F C +VL+T P +S Q + F + N +P Y+ +
Sbjct: 2883 HSFDGRKFDFQGTCNYVLAT--TGCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVVTVA 2939
Query: 1556 INDRN---------TVKVNGTQVNVPFITG---LATKIYSSEGFLVIDTSPDIQIYYNGF 1603
N V+VNG +P ++ +S+ LV D +Q+ Y+
Sbjct: 2940 ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFG--LQVSYDWN 2997
Query: 1604 NVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGM------Q 1657
+ +++ VCGLCGN + + +D V G S + SW+ G +
Sbjct: 2998 WRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDE 3057
Query: 1658 KRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLT-DMKGFFQPCYGLLDPLPFYES 1716
R P+C E + QY +G G+C L G F C+ + P F++
Sbjct: 3058 CRGSCPTCPEDRLEQY------------EGPGFCGPLAPGTGGPFTTCHAHVPPESFFKG 3105
Query: 1717 CYLDGCY-SHKKFQLCGSLAAYGEACRSFGILSTEWIEKENCSGVVEDPCVGADCPNRTC 1775
C LD C + LC +LA+Y AC++ G++ +W + C TC
Sbjct: 3106 CVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGC--------------EITC 3151
Query: 1776 ELGNGRELCG------CIEPPP 1791
+ E+CG C P P
Sbjct: 3152 PENSHYEVCGPPCPASCPSPAP 3173
Score = 783 bits (2023), Expect = 0.0
Identities = 469/1558 (30%), Positives = 717/1558 (46%), Gaps = 91/1558 (5%)
Query: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVE 318
GC ++ G+ F+ C CRC + E+ C+ +SC P+E C P G C AV
Sbjct: 3592 GCLHDDRYYPLGQTFYPGPGCDSLCRCRE-GGEVSCEPSSCGPHETCRPSGGSLGCVAVG 3650
Query: 319 TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWV 378
++TC G+PHY TFDG F F G+C Y+LA+ C L F+V +N VS
Sbjct: 3651 STTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVT 3710
Query: 379 KELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVT 438
+ ++V+V + + + + + +V VN + LPV L G ++ Q G +ETDFGL V
Sbjct: 3711 RVITVQVANFTLRLEQRQW-KVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVA 3769
Query: 439 FDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK 498
+D +Y ++VPG+Y CGLCGNYN +P DDF +P+G A + + G SW D
Sbjct: 3770 YDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSP 3829
Query: 499 C---------DSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHS 549
C +GC+ + +C E Y ++CG L+ GPL C +VDP +
Sbjct: 3830 CLPPPTCPPGSAGCIPS-DKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 3888
Query: 550 CVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSS 609
C++DLC N ++LC I AY CQA G + WR +T C ++CP SHY +C +
Sbjct: 3889 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFC--PMECPQNSHYELCADT 3946
Query: 610 CPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATA 669
C CS L+A C C EGC+C+ GF+ + CVP+ +CGC +G YY +
Sbjct: 3947 CSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLID- 4005
Query: 670 NCTVQCLCEEGGDVYCFNKTCGSGEVC-------------------------AVEDGYQG 704
NC QC C G V C +C G+VC E G QG
Sbjct: 4006 NCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQG 4065
Query: 705 -CFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKT-CPE-----RPEYLEIDINKK 757
C P E C L + H+FDG + F +Y L T CP + N+
Sbjct: 4066 VCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQN 4125
Query: 758 KPDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTV 817
+ + +++R + + + I +V++NG LP G++ + + + +
Sbjct: 4126 RGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALL 4185
Query: 818 ESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLES 877
+ + V Y + + L ++Y GLCG + N +++ PNG ++ ++ S
Sbjct: 4186 VADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGS 4245
Query: 878 WTT--FEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAY 935
W ++ +C EC C D L+ Y CG ++ + F CH V ++
Sbjct: 4246 WRAPGWDPLCWDECRGSCPTCPEDR--LEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESF 4303
Query: 936 YRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC-I 994
++ C+ +C GG+ LC ++A Y +AC+ A V + WR C + CPENSH+E C
Sbjct: 4304 FKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGP 4363
Query: 995 TCTETCET---LTLGPICVDSCSEGCQCDEGYALLGSQCVTRSE-CGCNFEGHQLATNET 1050
C +C + LT +C C EGCQCD G+ L +CV + CGC G
Sbjct: 4364 PCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSE 4423
Query: 1051 FWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYC-MEEGGLYYCQARTDASCIVSGYGHYL 1109
FW D C +C C + C C E C + G + CQ + A C G HY+
Sbjct: 4424 FWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYV 4483
Query: 1110 TFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYS 1169
T DG FDFQ +C +L P + F VT NE R + + V + ++ +S
Sbjct: 4484 TLDGHRFDFQGTCEYLLSAPCHGPPLGA-ENFTVTVANEHRGSQAVSYTRSVTLQIYNHS 4542
Query: 1170 IVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITV 1229
+ + + + V+ + LP +L ++ G VVV T GL + +D +F+ + V
Sbjct: 4543 LTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRV 4601
Query: 1230 PRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGCGD----RC 1285
P + S GLCG YN +P DDL+ G A Q GCG+ C
Sbjct: 4602 PAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQ-----------GCGECVSKPC 4650
Query: 1286 PSCAKVEGFSKV--QQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACS 1343
PS E C +I + + CH V P +++ CL D+C G C
Sbjct: 4651 PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCP 4710
Query: 1344 WLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCV 1403
+ Y + CQ G + WR C + CP +SHYE C C C ++ C C
Sbjct: 4711 AVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACR 4770
Query: 1404 EGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW-NSDCTRRCRCFRRNVIQC-DP 1461
EGC CDAG+VL+G +C+ CGC DG+YY ++F+ +C RRC C + C +
Sbjct: 4771 EGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEG 4830
Query: 1462 RQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLP 1521
C EEC L +GV+ C +T CLA GG + T DG +C++VL+ +C P
Sbjct: 4831 AACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKP 4890
Query: 1522 -DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATK 1580
D F +++ +K +A +L + + + + + V V+G V +P G +
Sbjct: 4891 GDEDFSIVL--EKNAAGDL---QRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVG-RVR 4944
Query: 1581 IYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKP 1640
+ + +V+ T+ +++ ++G + +SI + ++CGLCGNFNG+ +DD+V G
Sbjct: 4945 VTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSA 5004
Query: 1641 VVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGF 1700
S +W+ G K C E Q +C + + C +L + +G
Sbjct: 5005 ASSVETFGAAWRAPGSSK-----GCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGP 5059
Query: 1701 FQPCYGLLDPLPFYESCYLDGC-YSHKKFQLCGSLAAYGEACRSFGILSTEWIEKENC 1757
F C +L P ++ C D C K LC SLAAY AC++ G+ W C
Sbjct: 5060 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFC 5117
Score = 754 bits (1948), Expect = 0.0
Identities = 468/1605 (29%), Positives = 711/1605 (44%), Gaps = 111/1605 (6%)
Query: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVE 318
GC +G + G+ F+ C C C + + C+ +SC P+E C+P G C AV
Sbjct: 1190 GCVHQGTYHPPGQTFYPGPGCDSLCHCQE-GGLVSCESSSCGPHEACQPSGGSLGCVAVG 1248
Query: 319 TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWV 378
+STC G+PHY TFDG F F G+C Y+LA+ C L F+V +N VS
Sbjct: 1249 SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVT 1308
Query: 379 KELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVT 438
+ ++V+V + + + + + +V VN + LPV L G ++ Q G +ETDFGL V
Sbjct: 1309 RVITVQVANFTLRLEQRQW-KVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVA 1367
Query: 439 FDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK 498
+D +Y ++VPG+Y CGLCGNYN +P DDF +P+G A + + G SW D
Sbjct: 1368 YDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSP 1427
Query: 499 C---------DSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHS 549
C C+ + +C E Y ++CG L+ GPL C +VDP +
Sbjct: 1428 CLPPTPCPPGSEDCIPS-HKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 1486
Query: 550 CVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSS 609
C++DLC N ++LC I AY CQA G + WRT+T C ++CP SHY +C +
Sbjct: 1487 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFC--PMECPPNSHYELCADT 1544
Query: 610 CPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATA 669
C CS L+A C C EGC+C+ GF+ + CVP+ +CGC +G YY E
Sbjct: 1545 CSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYE-PEQTVLID 1603
Query: 670 NCTVQCLCEEGGDVYCFNKTCGSGEVC-------------------------AVEDGYQG 704
NC QC C G + C +C G+VC E G QG
Sbjct: 1604 NCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQG 1663
Query: 705 -CFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKT-CP-----ERPEYLEIDINKK 757
C P E C L + H+FDG + F +Y L T CP + N+
Sbjct: 1664 VCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQN 1723
Query: 758 KPDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTV 817
+ + +++R + + + I +V++NG LP G++ + + + +
Sbjct: 1724 RGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALL 1783
Query: 818 ESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLES 877
+ + V Y + + L ++Y GLCG + N +++ PNG ++ ++ S
Sbjct: 1784 VADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGS 1843
Query: 878 WTT--FEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAY 935
W ++ +C EC C D L+ Y CG + + F CH V ++
Sbjct: 1844 WRAPGWDPLCWDECRGSCPTCPEDR--LEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESF 1901
Query: 936 YRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC-I 994
++ C+ +C GG+ LC ++A Y +AC+ A V + WR C + CPENSH+E C
Sbjct: 1902 FKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGS 1961
Query: 995 TCTETCET---LTLGPICVDSCSEGCQCDEGYALLGSQCV-TRSECGCNFEGHQLATNET 1050
C +C + LT +C C EGCQCD G+ L +CV + CGC G
Sbjct: 1962 PCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSE 2021
Query: 1051 FWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYC-MEEGGLYYCQARTDASCIVSGYGHYL 1109
FW D C +C C + C C E C + G + CQ + A C G HY+
Sbjct: 2022 FWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYV 2081
Query: 1110 TFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYS 1169
T DG F+FQ +C +L P + F VT NE R + + V + ++ +S
Sbjct: 2082 TLDGHRFNFQGTCEYLLSAPCHGPPLGA-ENFTVTVANEHRGSQAVSYTRSVTLQIYNHS 2140
Query: 1170 IVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITV 1229
+ + + + V+ + LP +L ++ G VVV T GL + +D +F+ + V
Sbjct: 2141 LTLSARWPRKLQVDGVFVTLPFQL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRV 2199
Query: 1230 PRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGCGD----RC 1285
P + S GLCG YN +P DDL+ G A Q GCG+ C
Sbjct: 2200 PAAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQ-----------GCGECVSKPC 2248
Query: 1286 PS-CA--KVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTAC 1342
PS C + E F C +I + + CH V P +++ CL D+C G C
Sbjct: 2249 PSPCTPEQQESFGG-PDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLC 2307
Query: 1343 SWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYC 1402
+ Y + CQ G + WR C CP +SHYE C C C ++ C C
Sbjct: 2308 PAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESAC 2367
Query: 1403 VEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW-NSDCTRRCRCFRRNVIQCDP 1461
EGC CDAG+VL+G +C+ CGC D +YY Q F+ C CRC + C+P
Sbjct: 2368 REGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEP 2427
Query: 1462 RQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLP 1521
C E C G GC + ++ C A+G + TFDG F C +VL+ C P
Sbjct: 2428 SSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP 2487
Query: 1522 DI-SFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRN-TVKVNGTQVNVPFITGLAT 1579
+ F ++ W +++ + + + + R V VNG + +P +
Sbjct: 2488 GLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQ 2547
Query: 1580 KIYSSEGF-LVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRG 1638
S G +VI+T +++ Y+ +++++ +CGLCGN+NGD DD+ G
Sbjct: 2548 IRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNG 2607
Query: 1639 KPVVSSVVLAQSWK----TNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKL 1694
++ SW+ + P P +E + C +K Q + +C L
Sbjct: 2608 SQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIP--SEECPPELEKKYQKEEFCGLL 2665
Query: 1695 TDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQ-LCGSLAAYGEACRSFGILSTEWIE 1753
+ G C+ L+DP + C D C LC ++ AY AC++ G W
Sbjct: 2666 SSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRN 2725
Query: 1754 KENCSGVVEDPCVGADCPNR--------TCELGNGRELCGCIEPP 1790
+ C +CP TC LG C + P
Sbjct: 2726 ETFCP---------MECPQNSHYELCADTCSLG-----CSALSAP 2756
Score = 737 bits (1902), Expect = 0.0
Identities = 444/1435 (30%), Positives = 684/1435 (47%), Gaps = 81/1435 (5%)
Query: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVE 318
GC G + + D NC +C C + CQE SC P +VC+P G C +
Sbjct: 3988 GCYHNGVYYEPEQTVLID-NCRQQCTC-HVGKVVVCQEHSCKPGQVCQPSGGILSCVTKD 4045
Query: 319 T--------------------------STCVVFGEPHYHTFDGFLFHFQGSCAYLLARQ- 351
+TC ++G+PHYH+FDG F FQG+C Y+LA
Sbjct: 4046 PCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 4105
Query: 352 C--LQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSL 409
C + T L F+V KN++R AVS+V+ ++V G I I K G+V+VN ++T+L
Sbjct: 4106 CPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 4165
Query: 410 PVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPL 469
PV++ G + + Q + DFGL V++D +++P SY + CGLCGN ++NP
Sbjct: 4166 PVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPN 4225
Query: 470 DDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNK 529
+D + P+G A S+ G SWR D C C +C C Y G +CG L+
Sbjct: 4226 NDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSS 4285
Query: 530 -TDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQ 588
T GP C V P +F CV D+C + +LC+A+ +Y CQA G+ I DWR Q
Sbjct: 4286 GTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQ 4345
Query: 589 TGCVSTVQCPSFSHYSVCTSSCPDTC---SDLTASRNCATPCTEGCECNQGFVLSTSQCV 645
GC T CP SHY VC CP +C + LT C PC EGC+C+ GFVLS +CV
Sbjct: 4346 VGCEIT--CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCV 4403
Query: 646 PLHK-CGCDFDGHYYTMGEFFWATANCTVQCLCEEGG-DVYCFNKTCGSGEVCAV-EDGY 702
PL+ CGC +G Y+ G FWA C+ C C GG + C +CG GEVC + G
Sbjct: 4404 PLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQ 4463
Query: 703 QGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERP---EYLEIDI-NKKK 758
GC P C + T DG + F Y L C P E + + N+ +
Sbjct: 4464 HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHR 4523
Query: 759 PDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVE 818
++ R + + + + + + +++++G V LPF S L + + V
Sbjct: 4524 GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDS-LLHAHLSGADVVVT 4582
Query: 819 SKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESW 878
+ +++ + + +R+ Y GLCG YN + +D+ GK W
Sbjct: 4583 TTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GW 4634
Query: 879 TTFEEICNGECGDLLKACNNDS--ELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYY 936
GEC + K C + E + + CG+I+ ++ CHG+V Y+
Sbjct: 4635 QVGGAQGCGEC--VSKPCPSPCTPEQQESFGGPDACGVIS-ATDGPLAPCHGLVPPAQYF 4691
Query: 937 RTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC-IT 995
+ CL CQ G+ LC +VA Y +AC+ A ++G WR DFCPL+CP +SH+E C +
Sbjct: 4692 QGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDS 4751
Query: 996 CTETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDL 1055
C +C +L+ C +C EGC CD G+ L G CV +CGC +G E F+
Sbjct: 4752 CPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGP 4811
Query: 1056 DCQIFCYCSGTDNRVHC-ETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGF 1114
+C+ C C G V C E C E C E G+ C A C+ +G HY+T DG
Sbjct: 4812 ECERRCEC-GPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 4870
Query: 1115 PFDFQTSCPLILCTT-GSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIH 1173
+D SC +L +P + F +V KN D ++++ VTV G V+
Sbjct: 4871 VYDLHGSCSYVLAQVCHPKPGDEDFS--IVLEKNAAGD------LQRLLVTVAGQ--VVS 4920
Query: 1174 RAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSM 1233
A V V+ E + LP+ +G ++ + + G ++V++T GL++++D L +++P
Sbjct: 4921 LAQGQQVTVDGEAVALPVAVG--RVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPF 4978
Query: 1234 QNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTF--CQVGCGDR-CPSCAK 1290
+ GLCG +NGN DD +P G ASSV FG +W + C GCG + CP C
Sbjct: 4979 RGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLA 5038
Query: 1291 VEGFS-KVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYA 1349
E + + C + N F+ C + ++P+ +++ C++D C G C L Y
Sbjct: 5039 EETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 5098
Query: 1350 STCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCD 1409
+ CQ G+ V WR + C + CP +SHY C CQ CAA+ + C+ C EGC CD
Sbjct: 5099 AACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECD 5158
Query: 1410 AGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEE 1469
++L+ CI CGC +G+Y SDC+ RC C + + C C
Sbjct: 5159 DRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRV 5218
Query: 1470 CALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPD-ISFQLI 1528
C ++ R C++T+ C+ + G TFDGA + + LS+ C L + I + +
Sbjct: 5219 CEVKAEARNCWATR-GLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRV 5277
Query: 1529 INFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKI-YSSEGF 1587
+ + + V+ + + + + V VNG +V++P + + + +G
Sbjct: 5278 VAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGS 5337
Query: 1588 LVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVV 1642
L++ +Q++ + + +S K+CG CGNF+GD T+D+ + KP +
Sbjct: 5338 LLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAM 5392
>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
sapiens]
Length = 3003
Score = 848 bits (2191), Expect = 0.0
Identities = 508/1575 (32%), Positives = 743/1575 (47%), Gaps = 121/1575 (7%)
Query: 294 CQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCL 353
C+ C+ + C+ G C A T+ C G+PHY TFDG + G+C+Y + C
Sbjct: 444 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 503
Query: 354 QTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTL 413
+ +LP FSVEAKNEHR VS+V ++V + + + +G G V V++ + LPV+L
Sbjct: 504 EDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSL 563
Query: 414 DLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFL 473
G +++YQSG VE FGL+VT+D ++S+P + + CGLCGNYN +P DDFL
Sbjct: 564 SEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 623
Query: 474 RPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGP 533
PDG A ++ SW++ D+ C+ GC +NC C Y G CG L K DGP
Sbjct: 624 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 683
Query: 534 LWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVS 593
C +DP F+ CVYDLC V LC+ + AYA C LGI +GDWR+ C
Sbjct: 684 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC-- 741
Query: 594 TVQCPSFSHYSVCTSSCPDTCSDLTASRNCA-TPCTEGCECNQGFVLSTSQCVPLHKCGC 652
+ CP+ S Y +C +CP +C+ A NC+ PC EGC C GFV S CVP CGC
Sbjct: 742 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801
Query: 653 DFDGHYYTMGEFFWATANCTVQCLCEEG-GDVYCFNK-TCGSGEVCAVEDGYQGCFPKRE 710
F G G+ WA C +C C V C +K +C +GE C+V++G GC+P R
Sbjct: 802 TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 861
Query: 711 TVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPER---PEYLEIDINKKKPDAGPAWLR 767
C S + +FDG + F +Y L+ +C + P + + N+ + ++ R
Sbjct: 862 GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTR 921
Query: 768 GLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQY 827
+R+ +V + +V ++ LPF G+++++R V + +TV Y
Sbjct: 922 AVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTY 981
Query: 828 SDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNG 887
+ ++ ++Y GLCG +N + +D+ L G N F SW EE G
Sbjct: 982 DWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ--EETRPG 1039
Query: 888 ----ECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRL 943
E GD K DS + + +S++ CGI+ DP F ECH ++ R C++
Sbjct: 1040 CGATEPGDCPKL---DSLVAQQLQSKNECGILADP-KGPFRECHSKLDPQGAVRDCVYDR 1095
Query: 944 CQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC-ITCTETCET 1002
C G LCD++A YA+AC+ A V PWR+ + CPL CP +SH+E C C +C
Sbjct: 1096 CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGD 1155
Query: 1003 LTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCY 1062
L + C C EGC CDEG+AL G C+ + CGC +G +TF+ C C+
Sbjct: 1156 LPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCH 1215
Query: 1063 CSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSC 1122
C V CE+ C E C GG C A ++C SG HY TFDG FDF +C
Sbjct: 1216 CQ-EGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC 1274
Query: 1123 PLILC-TTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVL 1181
+L T G+RP +F V +N + + V V +++ + + + V
Sbjct: 1275 VYVLAQTCGTRP---GLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQR-QWKVT 1330
Query: 1182 VNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLC 1241
VN + LP+ L G+I G VV+ETDFGL+V YD ++ +TVP + GLC
Sbjct: 1331 VNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLC 1390
Query: 1242 GRYNGNPDDDLEMPMGLLASSVNEFGQSWVK--------RDTFCQVGCGDRCPS--C-AK 1290
G YNG+P DD + P G A + NEFG SW + T C G D PS C +
Sbjct: 1391 GNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPE 1450
Query: 1291 VEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYAS 1350
+E + ++ C L+ + S CH V+P K+C+FD C+ GG + CS + Y S
Sbjct: 1451 LEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVS 1510
Query: 1351 TCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDA 1410
CQ G V WR T C + CPPNSHYE C C C+A+ C C EGC CD+
Sbjct: 1511 ACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDS 1570
Query: 1411 GYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEEC 1470
G++ NG++C+ CGCY +G YYEP+Q +C ++C C + C CK + C
Sbjct: 1571 GFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVC 1630
Query: 1471 ALRNGVRGCFSTKTSY---------CLAAGG-GV----------------FRTFDGAFLR 1504
G+ C + + C GG GV + +FDG
Sbjct: 1631 QPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 1690
Query: 1505 FPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRN---- 1560
F C +VL+T P +S Q + F + N +P Y+ + N
Sbjct: 1691 FQGTCNYVLAT--TGCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVVTVAALGTNISIH 1747
Query: 1561 -------TVKVNGTQVNVPFITG---LATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISI 1610
V VNG +P ++ +S+ LV D +Q+ Y+ + +++
Sbjct: 1748 KDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFG--LQVSYDWNWRVDVTL 1805
Query: 1611 SERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGM------QKRPLAPS 1664
VCGLCGN + + +D V G S + SW+ G + R P+
Sbjct: 1806 PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT 1865
Query: 1665 CNELQFSQYAAMCDNVHIQKMQGDGYCLKL-TDMKGFFQPCYGLLDPLPFYESCYLDGCY 1723
C E + QY +G G+C L + G F C+ + P F++ C LD C
Sbjct: 1866 CPEDRLEQY------------EGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCM 1913
Query: 1724 -SHKKFQLCGSLAAYGEACRSFGILSTEWIEKENCSGVVEDPCVGADCPNRTCELGNGRE 1782
+ LC +LA+Y AC++ G++ +W + C TC + E
Sbjct: 1914 GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGC--------------EITCPENSHYE 1959
Query: 1783 LCG------CIEPPP 1791
+CG C P P
Sbjct: 1960 VCGPPCPASCPSPAP 1974
Score = 848 bits (2191), Expect = 0.0
Identities = 501/1581 (31%), Positives = 736/1581 (46%), Gaps = 88/1581 (5%)
Query: 239 VNVPGRWAFKVDGKEIDPAN--GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQE 296
V +PG F G PA+ GCT +G L G+ W D C +C C +++ C++
Sbjct: 781 VCLPG---FVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 837
Query: 297 -ASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQT 355
SC E C + C TC G+PHY +FDG F F G+C YLL C Q
Sbjct: 838 KQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQN 897
Query: 356 SSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDL 415
++LP F V +NEHR VS+ + + VE G K+ + + G+V V+D++ LP
Sbjct: 898 AALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAAD 957
Query: 416 GTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRP 475
G V++++ G V TDFGL VT+D + VP SY + CGLCGN+N +P DD
Sbjct: 958 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
Query: 476 DGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLW 535
G A + L G SW+ C + +C + D+ + CG L GP
Sbjct: 1018 GGGQAANALAFGNSWQ-EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFR 1076
Query: 536 ECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTV 595
EC + +DP V CVYD C + LC A+ YA CQA G + WR++ C +
Sbjct: 1077 ECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELC--PL 1134
Query: 596 QCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFD 655
CP SHY C+ CP +C DL C + C EGC C++GF LS C+PL CGC
Sbjct: 1135 SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQ 1194
Query: 656 GHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLL 715
G Y+ G+ F+ C C C+EGG V C + +CG E C G GC + C
Sbjct: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQA 1254
Query: 716 SQNQVLHTFDGASYAFPSEFSYTLLKTCPERP---EYLEIDINKKKPDAGPAWLRGLRIL 772
S + TFDG + F Y L +TC RP + + N + + R + +
Sbjct: 1255 SGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQ 1314
Query: 773 VADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGL 832
VA+ +++ +V +NG +++LP +G++ ++ + +E+ + V Y +
Sbjct: 1315 VANFTLRLEQ-RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYY 1373
Query: 833 LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEI-------- 884
+ + + Y+ GLCG YN + D+F PNG N F SW EE+
Sbjct: 1374 VRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSW---EEVVPDSPCLP 1430
Query: 885 ---CNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLF 941
C D + + EL K Y+ CG+++ P+ CH +V+ + C+F
Sbjct: 1431 PTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPT-GPLSSCHKLVDPQGPLKDCIF 1489
Query: 942 RLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECI-TCTETC 1000
LC GGN S LC ++ Y SAC+ A V PWRT FCP+ECP NSH+E C TC+ C
Sbjct: 1490 DLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC 1549
Query: 1001 ETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIF 1060
L+ P C D C+EGCQCD G+ G CV +CGC G +T +D +C+
Sbjct: 1550 SALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLID-NCRQQ 1608
Query: 1061 CYCSGTDNRV-------------------------HCETIPCKDDEYCMEEGGLYYCQAR 1095
C C V C + C+ E C E+GG C
Sbjct: 1609 CTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPN 1668
Query: 1096 TDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTG-SRPSSDSFPKFVVTAKNEDRDPSL 1154
+A+C + G HY +FDG FDFQ +C +L TTG S+ F VT KN++R
Sbjct: 1669 YEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPA 1728
Query: 1155 ALWVKQVDVTVFGYSIVIHR--AYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETD 1212
+V+ V V G +I IH+ K V VN LP+ + G+I++ ++ D
Sbjct: 1729 VSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVAD 1788
Query: 1213 FGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVK 1272
FGL+V YDW + +T+P S + GLCG + NP++D P G LA S+ +G SW
Sbjct: 1789 FGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRA 1848
Query: 1273 R--DTFCQVGCGDRCPSCA--KVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCL 1328
D C C CP+C ++E + L F+ CH+ V P F+K C+
Sbjct: 1849 PGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCV 1908
Query: 1329 FDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPR 1388
D C+ GG C L +Y + CQ G+ + WR C +TCP NSHYE C C
Sbjct: 1909 LDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPAS 1968
Query: 1389 C---AAIRLKSDCSHYCVEGCHCDAGYVLNGKSCI-LPHSCGCYSDGKYYEPKQLFW-NS 1443
C A + + C CVEGC CDAG+VL+ C+ L + CGC+++G Y+E FW +
Sbjct: 1969 CPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADG 2028
Query: 1444 DCTRRCRCF-RRNVIQCDPRQCKSDEECA-LRNGVRGCFSTKTSYCLAAGGGVFRTFDGA 1501
C++ CRC + C P C E C L +G GC T+ C A G + T DG
Sbjct: 2029 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGH 2088
Query: 1502 FLRFPANCAFVLSTICQKLP--DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDR 1559
F C ++LS C P +F + + + + ++ V I + ++ R
Sbjct: 2089 RFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR 2148
Query: 1560 --NTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNK 1617
++V+G V +PF + S +V+ T+ + + ++G + +++ +
Sbjct: 2149 WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAAS 2208
Query: 1618 VCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMC 1677
+CGLCGN+N D DD + GKP W+ G Q C E + C
Sbjct: 2209 LCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQ------GCGECVSKPCPSPC 2254
Query: 1678 DNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGC-YSHKKFQLCGSLAA 1736
+ G C ++ G PC+GL+ P +++ C LD C LC ++A
Sbjct: 2255 TPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVAT 2314
Query: 1737 YGEACRSFGILSTEWIEKENC 1757
Y AC++ G EW + C
Sbjct: 2315 YVAACQAAGAQLGEWRRPDFC 2335
Score = 778 bits (2010), Expect = 0.0
Identities = 473/1561 (30%), Positives = 718/1561 (45%), Gaps = 95/1561 (6%)
Query: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVE 318
GC +G + G+ F+ C C C + + C+ +SC P+E C+P G C AV
Sbjct: 1190 GCVHQGTYHPPGQTFYPGPGCDSLCHCQE-GGLVSCESSSCGPHEACQPSGGSLGCVAVG 1248
Query: 319 TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWV 378
+STC G+PHY TFDG F F G+C Y+LA+ C L F+V +N VS
Sbjct: 1249 SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVT 1308
Query: 379 KELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVT 438
+ ++V+V + + + + + +V VN + LPV L G ++ Q G +ETDFGL V
Sbjct: 1309 RVITVQVANFTLRLEQRQW-KVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVA 1367
Query: 439 FDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK 498
+D +Y ++VPG+Y CGLCGNYN +P DDF +P+G A + + G SW D
Sbjct: 1368 YDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSP 1427
Query: 499 C---------DSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHS 549
C C+ + +C E Y ++CG L+ GPL C +VDP +
Sbjct: 1428 CLPPTPCPPGSEDCIPS-HKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 1486
Query: 550 CVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSS 609
C++DLC N ++LC I AY CQA G + WRT+T C ++CP SHY +C +
Sbjct: 1487 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFC--PMECPPNSHYELCADT 1544
Query: 610 CPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATA 669
C CS L+A C C EGC+C+ GF+ + CVP+ +CGC +G YY E
Sbjct: 1545 CSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYE-PEQTVLID 1603
Query: 670 NCTVQCLCEEGGDVYCFNKTCGSGEVC-------------------------AVEDGYQG 704
NC QC C G + C +C G+VC E G QG
Sbjct: 1604 NCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQG 1663
Query: 705 -CFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKT-CP-----ERPEYLEIDINKK 757
C P E C L + H+FDG + F +Y L T CP + N+
Sbjct: 1664 VCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQN 1723
Query: 758 KPDAGPAWLRGLRILVADQEVKI--GGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNST 815
+ + +++R + + + I IG V +NG LP G++ + + +
Sbjct: 1724 RGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKA 1783
Query: 816 TVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFL 875
+ + + V Y + + L ++Y GLCG + N +++ PNG ++ ++
Sbjct: 1784 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 1843
Query: 876 ESWTT--FEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVT 933
SW ++ +C EC C D L+ Y CG + + F CH V
Sbjct: 1844 GSWRAPGWDPLCWDECRGSCPTCPEDR--LEQYEGPGFCGPLASGTGGPFTTCHAHVPPE 1901
Query: 934 AYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC 993
++++ C+ +C GG+ LC ++A Y +AC+ A V + WR C + CPENSH+E C
Sbjct: 1902 SFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVC 1961
Query: 994 -ITCTETCET---LTLGPICVDSCSEGCQCDEGYALLGSQCV-TRSECGCNFEGHQLATN 1048
C +C + LT +C C EGCQCD G+ L +CV + CGC G
Sbjct: 1962 GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAG 2021
Query: 1049 ETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYC-MEEGGLYYCQARTDASCIVSGYGH 1107
FW D C +C C + C C E C + G + CQ + A C G H
Sbjct: 2022 SEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPH 2081
Query: 1108 YLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFG 1167
Y+T DG FDFQ +C +L P + F VT NE R + + V + ++
Sbjct: 2082 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGA-ENFTVTVANEHRGSQAVSYTRSVTLQIYN 2140
Query: 1168 YSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSI 1227
+S+ + + + V+ + LP +L ++ G VVV T GL + +D +F+ +
Sbjct: 2141 HSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL 2199
Query: 1228 TVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGCGD---- 1283
VP + S GLCG YN +P DDL+ G A Q GCG+
Sbjct: 2200 RVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQ-----------GCGECVSK 2248
Query: 1284 RCPS-CA--KVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQT 1340
CPS C + E F C +I + + CH V P +++ CL D+C G
Sbjct: 2249 PCPSPCTPEQQESFGG-PDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGG 2307
Query: 1341 ACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSH 1400
C + Y + CQ G + WR C + CP +SHYE C C C ++ C
Sbjct: 2308 LCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCES 2367
Query: 1401 YCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW-NSDCTRRCRCFRRNVIQC 1459
C EGC CDAG+VL+G +C+ CGC DG+YY ++F+ +C RRC C + C
Sbjct: 2368 ACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTC 2427
Query: 1460 -DPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQ 1518
+ C EEC L +GV+ C +T CLA GG + T DG +C++VL+ +C
Sbjct: 2428 QEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCH 2487
Query: 1519 KLP-DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGL 1577
P D F +++ +K +A +L + + + + + V V+G V +P G
Sbjct: 2488 PKPGDEDFSIVL--EKNAAGDL---QRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVG- 2541
Query: 1578 ATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLR 1637
++ + +V+ T+ +++ ++G + +SI + ++CGLCGNFNG+ +DD+V
Sbjct: 2542 RVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPN 2601
Query: 1638 GKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDM 1697
G S +W+ G K C E Q +C + + C +L +
Sbjct: 2602 GSAASSVETFGAAWRAPGSSK-----GCGEGCGPQGCPVCLAEETAPYESNEACGQLRNP 2656
Query: 1698 KGFFQPCYGLLDPLPFYESCYLDGC-YSHKKFQLCGSLAAYGEACRSFGILSTEWIEKEN 1756
+G F C +L P ++ C D C K LC SLAAY AC++ G+ W
Sbjct: 2657 QGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSF 2716
Query: 1757 C 1757
C
Sbjct: 2717 C 2717
Score = 730 bits (1884), Expect = 0.0
Identities = 444/1437 (30%), Positives = 684/1437 (47%), Gaps = 83/1437 (5%)
Query: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVE 318
GC G + + D NC +C C + CQE SC P +VC+P G C +
Sbjct: 1586 GCYHNGVYYEPEQTVLID-NCRQQCTC-HAGKGMVCQEHSCKPGQVCQPSGGILSCVTKD 1643
Query: 319 T--------------------------STCVVFGEPHYHTFDGFLFHFQGSCAYLLARQ- 351
+TC ++G+PHYH+FDG F FQG+C Y+LA
Sbjct: 1644 PCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 1703
Query: 352 C--LQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKV--NDLVT 407
C + T L F+V KN++R AVS+V+ ++V G I I K G+V+V N ++T
Sbjct: 1704 CPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLT 1763
Query: 408 SLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKN 467
+LPV++ G + + Q + DFGL V++D +++P SY + CGLCGN ++N
Sbjct: 1764 ALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRN 1823
Query: 468 PLDDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFL 527
P +D + P+G A S+ G SWR D C C +C C Y G +CG L
Sbjct: 1824 PNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPL 1883
Query: 528 -NKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWR 586
+ T GP C V P +F CV D+C + +LC+A+ +Y CQA G+ I DWR
Sbjct: 1884 ASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWR 1943
Query: 587 TQTGCVSTVQCPSFSHYSVCTSSCPDTC---SDLTASRNCATPCTEGCECNQGFVLSTSQ 643
Q GC T CP SHY VC CP +C + LT C PC EGC+C+ GFVLS +
Sbjct: 1944 AQVGCEIT--CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADR 2001
Query: 644 CVPLHK-CGCDFDGHYYTMGEFFWATANCTVQCLCEEGG-DVYCFNKTCGSGEVCAV-ED 700
CVPL+ CGC +G Y+ G FWA C+ C C GG + C +CG GEVC +
Sbjct: 2002 CVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPS 2061
Query: 701 GYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERP---EYLEIDI-NK 756
G GC P C + T DG + F Y L C P E + + N+
Sbjct: 2062 GQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE 2121
Query: 757 KKPDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTT 816
+ ++ R + + + + + + +++++G V LPF S L + +
Sbjct: 2122 HRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDS-LLHAHLSGADVV 2180
Query: 817 VESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLE 876
V + +++ + + +R+ Y GLCG YN + +D+ GK
Sbjct: 2181 VTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA-------- 2232
Query: 877 SWTTFEEICNGECGDLLKACNNDS--ELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTA 934
W GEC + K C + E + + CG+I+ ++ CHG+V
Sbjct: 2233 GWQVGGAQGCGEC--VSKPCPSPCTPEQQESFGGPDACGVIS-ATDGPLAPCHGLVPPAQ 2289
Query: 935 YYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC- 993
Y++ CL CQ G+ LC +VA Y +AC+ A ++G WR DFCPL+CP +SH+E C
Sbjct: 2290 YFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCG 2349
Query: 994 ITCTETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWV 1053
+C +C +L+ C +C EGC CD G+ L G CV +CGC +G E F+
Sbjct: 2350 DSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYP 2409
Query: 1054 DLDCQIFCYCSGTDNRVHC-ETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFD 1112
+C+ C C G V C E C E C E G+ C A C+ +G HY+T D
Sbjct: 2410 GPECERRCEC-GPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLD 2468
Query: 1113 GFPFDFQTSCPLILCTT-GSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIV 1171
G +D SC +L +P + F +V KN D ++++ VTV G V
Sbjct: 2469 GRVYDLHGSCSYVLAQVCHPKPGDEDFS--IVLEKNAAGD------LQRLLVTVAGQ--V 2518
Query: 1172 IHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPR 1231
+ A V V+ E + LP+ +G ++ + + G ++V++T GL++++D L +++P
Sbjct: 2519 VSLAQGQQVTVDGEAVALPVAVG--RVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPS 2576
Query: 1232 SMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTF--CQVGCGDR-CPSC 1288
+ GLCG +NGN DD +P G ASSV FG +W + C GCG + CP C
Sbjct: 2577 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVC 2636
Query: 1289 AKVEGFS-KVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQN 1347
E + + C + N F+ C + ++P+ +++ C++D C G C L
Sbjct: 2637 LAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAA 2696
Query: 1348 YASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCH 1407
Y + CQ G+ V WR + C + CP +SHY C CQ CAA+ + C+ C EGC
Sbjct: 2697 YTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCE 2756
Query: 1408 CDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSD 1467
CD ++L+ CI CGC +G+Y SDC+ RC C + + C C
Sbjct: 2757 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 2816
Query: 1468 EECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPD-ISFQ 1526
C ++ R C++T+ C+ + G TFDGA + + LS+ C L + I +
Sbjct: 2817 RVCEVKAEARNCWATR-GLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWY 2875
Query: 1527 LIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKI-YSSE 1585
++ + + V+ + + + + V VNG +V++P + + + +
Sbjct: 2876 RVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPD 2935
Query: 1586 GFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVV 1642
G L++ +Q++ + + +S K+CG CGNF+GD T+D+ + KP +
Sbjct: 2936 GSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAM 2992
>gi|239757282 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1403
Score = 731 bits (1888), Expect = 0.0
Identities = 434/1374 (31%), Positives = 667/1374 (48%), Gaps = 53/1374 (3%)
Query: 294 CQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQ-C 352
C +C P E C+ +G C +TC ++G+PHYH+FDG F FQG+C Y+LA C
Sbjct: 47 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 106
Query: 353 L--QTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLP 410
L T L F+V KNE+R AVS+V+ ++V G I I K G+V+VN ++T+LP
Sbjct: 107 LGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 166
Query: 411 VTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLD 470
V++ G + + Q + DFGL V++D +++P SY + CGLCGN ++NP +
Sbjct: 167 VSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 226
Query: 471 DFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNK- 529
D + P+G A S+ G SWR D C C +C C Y G +CG L
Sbjct: 227 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPG 286
Query: 530 TDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQT 589
T GP C V P +F CV D+C + +LC+A+ +Y CQA G+ I DWR Q
Sbjct: 287 TGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQV 346
Query: 590 GCVSTVQCPSFSHYSVCTSSCPDTC---SDLTASRNCATPCTEGCECNQGFVLSTSQCVP 646
GC T CP SHY VC CP +C + LT C PC EGC+C+ GFVLS +CVP
Sbjct: 347 GCEIT--CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVP 404
Query: 647 LHK-CGCDFDGHYYTMGEFFWATANCTVQCLCEEGG-DVYCFNKTCGSGEVCAV-EDGYQ 703
L+ CGC +G Y+ G FWA C+ C C GG + C +CG GEVC + G
Sbjct: 405 LNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH 464
Query: 704 GCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERP---EYLEIDI-NKKKP 759
GC P C + T DG + F Y L C P E + + N+ +
Sbjct: 465 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 524
Query: 760 DAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVES 819
++ R + + + + + + +++++G V LPF S L + + V +
Sbjct: 525 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDS-LLHAHLSGADVVVTT 583
Query: 820 KGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWT 879
+++ + + +R+ Y GLCG YN + +D+ GK W
Sbjct: 584 TSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQ 635
Query: 880 TFEEICNGECGDLLKACNNDS--ELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYR 937
GEC + K C + E + + CG+I+ ++ CHG+V Y++
Sbjct: 636 VGGAQGCGEC--VSKPCPSPCTPEQQESFGGPDACGVIS-ATDGPLAPCHGLVPPAQYFQ 692
Query: 938 TCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC-ITC 996
CL CQ G+ LC +VA Y +AC+ A ++G WR DFCPL+CP +SH+E C +C
Sbjct: 693 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 752
Query: 997 TETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLD 1056
+C +L+ C +C EGC CD G+ L G CV +CGC +G E F+ +
Sbjct: 753 PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE 812
Query: 1057 CQIFCYCSGTDNRVHC-ETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFP 1115
C+ C C G V C E C E C E G+ C A C+ +G HY+T DG
Sbjct: 813 CERRCEC-GPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRV 871
Query: 1116 FDFQTSCPLILCTT-GSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHR 1174
+D SC +L +P + F +V KN D ++++ VTV G V+
Sbjct: 872 YDLHGSCSYVLAQVCHPKPGDEDFS--IVLEKNAAGD------LQRLLVTVAGQ--VVSL 921
Query: 1175 AYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQ 1234
A V V+ E + LP+ +G ++ + + G ++V++T GL++++D L +++P +
Sbjct: 922 AQGQQVTVDGEAVALPVAVG--RVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 979
Query: 1235 NSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTF--CQVGCGDR-CPSCAKV 1291
GLCG +NGN DD +P G ASSV FG +W + C GCG + CP C
Sbjct: 980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAE 1039
Query: 1292 EGFS-KVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYAS 1350
E + + C + N F+ C + ++P+ +++ C++D C G C L Y +
Sbjct: 1040 ETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTA 1099
Query: 1351 TCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDA 1410
CQ G+ V WR + C + CP +SHY C CQ CAA+ + C+ C EGC CD
Sbjct: 1100 ACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDD 1159
Query: 1411 GYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEEC 1470
++L+ CI CGC +G+Y SDC+ RC C + + C C C
Sbjct: 1160 RFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVC 1219
Query: 1471 ALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPD-ISFQLII 1529
++ R C++T+ C+ + G TFDGA + + LS+ C L + I + ++
Sbjct: 1220 EVKAEARNCWATR-GLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVV 1278
Query: 1530 NFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKI-YSSEGFL 1588
+ + V+ + + + + V VNG +V++P + + + +G L
Sbjct: 1279 AEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSL 1338
Query: 1589 VIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVV 1642
++ +Q++ + + +S K+CG CGNF+GD T+D+ + KP +
Sbjct: 1339 LVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAM 1392
Score = 496 bits (1276), Expect = e-139
Identities = 294/865 (33%), Positives = 419/865 (48%), Gaps = 36/865 (4%)
Query: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCE--PKGKFFYCSA 316
GC + G + G FW D C+ CRC + C ASC EVC P G+ C
Sbjct: 410 GCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQ-HGCQP 468
Query: 317 VETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCL-QTSSLPFFSVEAKNEHRRGSAV 375
V T+ C +G+PHY T DG F FQG+C YLL+ C F+V NEHR AV
Sbjct: 469 VSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAV 528
Query: 376 SWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGL 435
S+ + +++++ + + + +++V+ + +LP LD + + SG V T GL
Sbjct: 529 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLD-SLLHAHLSGADVVVTTTSGL 587
Query: 436 LVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHA 495
+ FDG + + VP +Y S CGLCGNYN++P DD G+PA W+V A
Sbjct: 588 SLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGA 639
Query: 496 DWKCDSGCVDNC-TQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDL 554
C C + C + + G D CG ++ TDGPL C +V P + C+ D
Sbjct: 640 Q-GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDA 698
Query: 555 CSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTC 614
C V+ + LC A+ Y CQA G +G+WR C +QCP+ SHY +C SCP +C
Sbjct: 699 CQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFC--PLQCPAHSHYELCGDSCPVSC 756
Query: 615 SDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQ 674
L+A C + C EGC C+ GFVLS CVP+ +CGC DG YY +GE F+ C +
Sbjct: 757 PSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERR 816
Query: 675 CLCEEGGDVYC-FNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPS 733
C C GG V C CG E C +EDG Q C CL + T DG Y
Sbjct: 817 CECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHG 876
Query: 734 EFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQ 793
SY L + C +P + I +K AG L+ L + VA Q V + +V ++G+
Sbjct: 877 SCSYVLAQVCHPKPGDEDFSIVLEKNAAGD--LQRLLVTVAGQVVSLA--QGQQVTVDGE 932
Query: 794 EVELPFFHPSGKLEI-YRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFY 852
V LP G++ + +N +KG+ + D LL + + + + GLCG +
Sbjct: 933 AVALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLL-MSIPSPFRGRLCGLCGNF 989
Query: 853 NANASDEFCLPNGKCTDNLAVFLESWTT--FEEICNGECGDL-LKACNNDSELLKFYRSR 909
N N SD+F LPNG ++ F +W + C CG C +E Y S
Sbjct: 990 NGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCL--AEETAPYESN 1047
Query: 910 SRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADV 969
CG + +P F C V++ + Y+R C++ LC G+++ LC S+A Y +AC+ A V
Sbjct: 1048 EACGQLRNP-QGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGV 1106
Query: 970 EVGPWRTYDFCPLECPENSHFEECI-TCTETCETLTLGPICVDSCSEGCQCDEGYALLGS 1028
V PWRT FCPL CP +SH+ C TC +C L+ C C EGC+CD+ + L
Sbjct: 1107 AVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQG 1166
Query: 1029 QCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGG 1088
C+ +CGC G L N + + DC C CS + + C+ C C +
Sbjct: 1167 VCIPVQDCGCTHNGRYLPVNSSL-LTSDCSERCSCSSSSG-LTCQAAGCPPGRVCEVKAE 1224
Query: 1089 LYYCQARTDASCIVSGYGHYLTFDG 1113
C A T C++S + TFDG
Sbjct: 1225 ARNCWA-TRGLCVLSVGANLTTFDG 1248
Score = 487 bits (1253), Expect = e-137
Identities = 307/1097 (27%), Positives = 484/1097 (44%), Gaps = 50/1097 (4%)
Query: 685 CFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKT-- 742
C TC E C + G C P E C L + H+FDG + F +Y L T
Sbjct: 47 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 106
Query: 743 ----CPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELP 798
+ N+ + + +++R + + + I +V++NG LP
Sbjct: 107 LGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 166
Query: 799 FFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASD 858
G++ + + + + + + V Y + + L ++Y GLCG + N ++
Sbjct: 167 VSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 226
Query: 859 EFCLPNGKCTDNLAVFLESWTT--FEEICNGECGDLLKACNNDSELLKFYRSRSRCGIIN 916
+ PNG ++ ++ SW ++ +C EC C D L+ Y CG +
Sbjct: 227 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDR--LEQYEGPGFCGPLA 284
Query: 917 DPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRT 976
+ F CH V ++++ C+ +C GG+ LC ++A Y +AC+ A V + WR
Sbjct: 285 PGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRA 344
Query: 977 YDFCPLECPENSHFEEC-ITCTETCET---LTLGPICVDSCSEGCQCDEGYALLGSQCVT 1032
C + CPENSH+E C C +C + LT +C C EGCQCD G+ L +CV
Sbjct: 345 QVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVP 404
Query: 1033 RSE-CGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYC-MEEGGLY 1090
+ CGC G FW D C +C C + C C E C + G +
Sbjct: 405 LNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH 464
Query: 1091 YCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDR 1150
CQ + A C G HY+T DG FDFQ +C +L P + F VT NE R
Sbjct: 465 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGA-ENFTVTVANEHR 523
Query: 1151 DPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVE 1210
+ + V + ++ +S+ + + + V+ + LP +L ++ G VVV
Sbjct: 524 GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVVT 582
Query: 1211 TDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSW 1270
T GL + +D +F+ + VP + S GLCG YN +P DDL+ G A Q
Sbjct: 583 TTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQ-- 640
Query: 1271 VKRDTFCQVGCGD----RCPSCAKVEGFSKV--QQLCSLIPNQNAAFSKCHSKVNPTFFY 1324
GCG+ CPS E C +I + + CH V P ++
Sbjct: 641 ---------GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYF 691
Query: 1325 KNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSV 1384
+ CL D+C G C + Y + CQ G + WR C + CP +SHYE C
Sbjct: 692 QGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDS 751
Query: 1385 CQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW-NS 1443
C C ++ C C EGC CDAG+VL+G +C+ CGC DG+YY ++F+
Sbjct: 752 CPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGP 811
Query: 1444 DCTRRCRCFRRNVIQC-DPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAF 1502
+C RRC C + C + C EEC L +GV+ C +T CLA GG + T DG
Sbjct: 812 ECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRV 871
Query: 1503 LRFPANCAFVLSTICQKLP-DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNT 1561
+C++VL+ +C P D F +++ +K +A +L + + + + +
Sbjct: 872 YDLHGSCSYVLAQVCHPKPGDEDFSIVL--EKNAAGDL---QRLLVTVAGQVVSLAQGQQ 926
Query: 1562 VKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGL 1621
V V+G V +P G ++ + +V+ T+ +++ ++G + +SI + ++CGL
Sbjct: 927 VTVDGEAVALPVAVG-RVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGL 985
Query: 1622 CGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVH 1681
CGNFNG+ +DD+V G S +W+ G K C E Q +C
Sbjct: 986 CGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSK-----GCGEGCGPQGCPVCLAEE 1040
Query: 1682 IQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGC-YSHKKFQLCGSLAAYGEA 1740
+ + C +L + +G F C +L P ++ C D C K LC SLAAY A
Sbjct: 1041 TAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAA 1100
Query: 1741 CRSFGILSTEWIEKENC 1757
C++ G+ W C
Sbjct: 1101 CQAAGVAVKPWRTDSFC 1117
Score = 307 bits (787), Expect = 6e-83
Identities = 193/611 (31%), Positives = 290/611 (47%), Gaps = 29/611 (4%)
Query: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQE-ASCSPYEVCEPKGKFFYCSAV 317
GC G++ GEVF+ C +C C + CQE A+C P+E C + C A
Sbjct: 793 GCLHDGRYYPLGEVFYPGPECERRCECGP-GGHVTCQEGAACGPHEECRLEDGVQACHAT 851
Query: 318 ETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSW 377
C+ G HY T DG ++ GSC+Y+LA+ C FS+ + +A
Sbjct: 852 GCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK-----NAAGD 906
Query: 378 VKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLV 437
++ L V V G + + +G +V V+ +LPV +G V++ G + ++T GL +
Sbjct: 907 LQRLLVTVAGQVVSLAQGQ--QVTVDGEAVALPVA--VGRVRVTAEGRNMVLQTTKGLRL 962
Query: 438 TFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADW 497
FDG + +S+P + CGLCGN+N N DDF+ P+G A SV G +WRV +
Sbjct: 963 LFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSK 1022
Query: 498 KCDSGC-VDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCS 556
C GC C C A A Y ++ CG L GP C V+ P+ + CVYDLC+
Sbjct: 1023 GCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA 1082
Query: 557 VRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSD 616
+ + LC+++ AY CQA G+ + WRT + C + CP+ SHYS+CT +C +C+
Sbjct: 1083 QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFC--PLHCPAHSHYSICTRTCQGSCAA 1140
Query: 617 LTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCL 676
L+ C T C EGCEC+ F+LS C+P+ CGC +G Y + T++C+ +C
Sbjct: 1141 LSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSL-LTSDCSERCS 1199
Query: 677 CEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFS 736
C + C C G VC V+ + C+ R +C+LS L TFDGA A S
Sbjct: 1200 CSSSSGLTCQAAGCPPGRVCEVKAEARNCWATR-GLCVLSVGANLTTFDGARGATTSPGV 1258
Query: 737 YTLLKTCP----ERPEY---LEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVK 789
Y L CP P Y E+ I K +A + + I D V + V
Sbjct: 1259 YELSSRCPGLQNTIPWYRVVAEVQICHGKTEA----VGQVHIFFQDGMVTL--TPNKGVW 1312
Query: 790 LNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLC 849
+NG V+LP + S V K V V G + + +S + G C
Sbjct: 1313 VNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGAC 1372
Query: 850 GFYNANASDEF 860
G ++ + ++++
Sbjct: 1373 GNFDGDQTNDW 1383
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 654 bits (1687), Expect = 0.0
Identities = 454/1577 (28%), Positives = 706/1577 (44%), Gaps = 98/1577 (6%)
Query: 274 WDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVE-TSTCVVFGEPHYHT 332
W NCT CRC + + CQ + C + VC+ K + C T+TC+V+G+PHY T
Sbjct: 1108 WFSPNCTEHCRCWP-GSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVT 1166
Query: 333 FDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILI 392
FDG F F G C Y+LA+ C S+ PFF V AKNE + VS + ++ V + + +
Sbjct: 1167 FDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTL 1225
Query: 393 PKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGS 452
KG R V +LP G V + SG ++T+FGL V +DG ++V +
Sbjct: 1226 LKGR--RTLVGGQQVTLPAIPSKG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSST 1282
Query: 453 YINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRV-YHADWKCDSGCVDNCTQCD 511
Y CGLCGNY+ N +D L+ DG PA +LG SW+ D +C V N CD
Sbjct: 1283 YSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCD 1342
Query: 512 AATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAY 571
++ ++ G +CG L T GP C V +F SC+ D+C + LLC +
Sbjct: 1343 SSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTM 1402
Query: 572 ALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGC 631
CQ G + WR C + CP S YS+C CPDTC + C+ C E C
Sbjct: 1403 TTTCQDAGHAVKPWREPHFC--PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEAC 1460
Query: 632 ECNQGFVLSTSQCVPLHKCGCDFD-GHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTC 690
ECN GFVLS +C+P +CGC G Y+ +GE W C C+CE + C C
Sbjct: 1461 ECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGE-RWYKPGCKELCVCESNNRIRCQPWRC 1519
Query: 691 GSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYL 750
+ E C +DG GC + C S + TFDGA + F +Y L + C R +
Sbjct: 1520 RAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDS 1579
Query: 751 EIDINKKKPDAG----PAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKL 806
++ + G ++++ + + V D + + + +V LNG V LP + G++
Sbjct: 1580 YFVVSATNENRGGILEVSYIKAVHVTVFDLSISL--LRGCKVMLNGHRVALPVWLAQGRV 1637
Query: 807 EIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGK 866
I + N + + + V+Y L+ + + ++Y GLCG YN N+ D+ P+ K
Sbjct: 1638 TIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697
Query: 867 CTDNLAVFLESWTTFEEICNG--ECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFL 924
+ +W E G G +C +S + ++ C I+ +P F
Sbjct: 1698 LAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKN---CAILINP-QGPFS 1753
Query: 925 ECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLEC 984
+CH VV + + +C+ C + G+ + LC S+ YAS C A + WR FCP+ C
Sbjct: 1754 QCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRC 1812
Query: 985 PENSHFEECIT-CTETCETLTLGPICVDS--CSEGCQCDEGYALLGSQCVTRSECGC-NF 1040
P S + C + C +TC ++ C + C+E C+C +G+ L G+ CV +CGC +
Sbjct: 1813 PPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDP 1872
Query: 1041 EGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASC 1100
G E ++ + C C CS N + C CK ++ C GL C+A C
Sbjct: 1873 AGSYHPVGERWYTENTCTRLCTCS-VHNNITCFQSTCKPNQICWALDGLLRCRASGVGVC 1931
Query: 1101 IVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSL-ALWVK 1159
+ G HY++FDG +C L+L P+ + P F ++AK+E + A +
Sbjct: 1932 QLPGESHYVSFDGSNHSIPDACTLVLVKV-CHPAM-ALPFFKISAKHEKEEGGTEAFRLH 1989
Query: 1160 QVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVY 1219
+V + ++ + + + H VL+NS+++ LP +++ S + +V G++V +
Sbjct: 1990 EVYIDIYDAQVTLQKG--HRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF 2047
Query: 1220 DWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKR--DTFC 1277
D L I +P + G+CG +N +D+L MP +A+S +EF SW + D C
Sbjct: 2048 DGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSC 2107
Query: 1278 QVGCGDRCPSCAKVE----GFSKVQQLCSLIPNQNAA-----FSKCHSKVNPTFFYKNCL 1328
Q D A+ + G + L AA +++C S+++ T F +C
Sbjct: 2108 QSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCA 2167
Query: 1329 FDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPR 1388
C GG Q C LQ + +TCQ+QG+ WRN + C + CP S Y +C+ C P
Sbjct: 2168 NTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPS 2227
Query: 1389 CAAIRLKSDCSHY---CVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW-NSD 1444
C + + + + C EGC C GYVL+ C+ CGC P W +S
Sbjct: 2228 CWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSG 2287
Query: 1445 CTRRCRCFRRNVIQCDPRQCKSDEECALR--NGVRGCFSTKTSYCLAAGGGVFRTFDGAF 1502
CT +C C IQC +C S C L N C S K+ C G + TFDG
Sbjct: 2288 CTEKCVC-TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFS 2346
Query: 1503 LRFPANCAFVLSTICQKLPD-ISFQLIINFDKWSAPNLTI-----ISPVYFYINEEQILI 1556
R +VL LP+ + L+ +K P +I I+ VY Y ++ +
Sbjct: 2347 YRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGY----KVQL 2402
Query: 1557 NDRNTVKVNGTQVNVPFITG--LATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERL 1614
+ VN ++ VP+ L ++ +LV D ++ + + G IS+
Sbjct: 2403 QAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDF--ELVVSFGGRKNAVISLPSMY 2460
Query: 1615 QNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKT---NGMQKRPLAPSCNE---- 1667
+ V GLCGN++ + +D + G + SW+ + + + P A E
Sbjct: 2461 EGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQG 2520
Query: 1668 ----LQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCY 1723
L+ + C + C L D +G F C+ + P PF E C LD C
Sbjct: 2521 AELGLRTGLQVSECSPEQLASNSTQA-CRVLADPQGPFAACHQTVAPEPFQEHCVLDLCS 2579
Query: 1724 S----HKKFQLCGSLAAYGEACRSFGILSTEWIEKENCSGVVEDPCVGADCPNR------ 1773
+ ++ C L+ Y C+ G W ++ C E PC+ C N
Sbjct: 2580 AQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLC----ESPCLQNPCQNDGQCREQ 2635
Query: 1774 ------TCELGNGRELC 1784
CE+G G LC
Sbjct: 2636 GATFTCECEVGYGGGLC 2652
Score = 547 bits (1409), Expect = e-155
Identities = 360/1229 (29%), Positives = 563/1229 (45%), Gaps = 92/1229 (7%)
Query: 247 FKVDGKEIDPANGCTS---RGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYE 303
F + G E P + C G + + GE W C C C + NN I CQ C E
Sbjct: 1466 FVLSGLECIPRSQCGCLHPAGSYFKVGER-WYKPGCKELCVC-ESNNRIRCQPWRCRAQE 1523
Query: 304 VCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSV 363
C + + C A +TC G+PHY TFDG L HF G+C Y+L R C S +F V
Sbjct: 1524 FCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVV 1583
Query: 364 EAKNEHRRGSA-VSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQ 422
A NE+R G VS++K + V V I + +G +V +N +LPV L G V I
Sbjct: 1584 SATNENRGGILEVSYIKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRL 1641
Query: 423 SGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMS 482
S + T+FGL V +DG H ++VP SY CGLCGNYN N LDD LRPD + A
Sbjct: 1642 SSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGD 1701
Query: 483 VLDLGESWRVYHADWKCDSGCV---DNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGT 539
+ LG +W++ + + GC + C + A + + C L GP +C
Sbjct: 1702 SMQLGAAWKLPESS---EPGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQ 1757
Query: 540 VVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPS 599
VV P + SCV+ C + + T LC+++QAYA +C G WR +T C ++CP
Sbjct: 1758 VVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFC--PMRCPP 1814
Query: 600 FSHYSVCTSSCPDTCSDLTASRNC--ATPCTEGCECNQGFVLSTSQCVPLHKCGC-DFDG 656
S YS C+S CPDTCS + R+C A PC E CEC +G +LS + CVPL +CGC D G
Sbjct: 1815 GSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAG 1874
Query: 657 HYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLS 716
Y+ +GE ++ CT C C ++ CF TC ++C DG C VC L
Sbjct: 1875 SYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLP 1934
Query: 717 QNQVLHTFDGASYAFPSEFSYTLLKTCPERP--EYLEIDINKKKPDAGPAWLRGLRILVA 774
+FDG++++ P + L+K C + +I +K + G R + +
Sbjct: 1935 GESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYID 1994
Query: 775 DQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLY 834
+ ++ V +N ++V LP + + + + V K V V++ LL
Sbjct: 1995 IYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLE 2054
Query: 835 IRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLL- 893
I + TTY+ G+CG +N DE +P+ + ++ + F+ SW ++ + C LL
Sbjct: 2055 IEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWK--DKDIDPSCQSLLV 2112
Query: 894 ----------KACNNDSELLKFYRSRSRC-GIINDPSNSSFLECHGVVNVTAYYRTCLFR 942
+ + + R+R +C + P + +C +++T + C
Sbjct: 2113 DEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAP---VWAQCASRIDLTPFLVDCANT 2169
Query: 943 LCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECI-TCTETCE 1001
LC+ GG LC ++ + + C++ ++ WR FCPLECP S + C+ +C+ +C
Sbjct: 2170 LCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCW 2229
Query: 1002 TL---TLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGC-NFEGHQLATNETFWVDLDC 1057
L G +C+EGC C GY L +CV RS+CGC + G + ++ WV C
Sbjct: 2230 DLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKS-WVSSGC 2288
Query: 1058 QIFCYCSGTDNRVHCETIPCKDDEYCM--EEGGLYYCQARTDASCIVSGYGHYLTFDGFP 1115
C C+G + C C +C + C + C V G YLTFDGF
Sbjct: 2289 TEKCVCTG--GAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFS 2346
Query: 1116 FDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRA 1175
+ Q +L T + +V +N+ P ++++++V TV+GY + +
Sbjct: 2347 YRLQGRMTYVLIKTVD-VLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAG 2405
Query: 1176 YKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQN 1235
+ ++VN++++ +P + + + + +G + + TDF L V + + I++P +
Sbjct: 2406 LE--LVVNNQKMAVPYRPNE-HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEG 2462
Query: 1236 STYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSW-VKRDTF----------------CQ 1278
GLCG Y+ N +D+ +P G L ++N FG SW VK + +
Sbjct: 2463 LVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAE 2522
Query: 1279 VG--CGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCI--- 1333
+G G + C+ + S Q C ++ + F+ CH V P F ++C+ D C
Sbjct: 2523 LGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQD 2582
Query: 1334 DGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIR 1393
+ C L YA CQ G + GWR+ T C C N C+ + A
Sbjct: 2583 PREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQNPCQND--GQCREQGATFT 2640
Query: 1394 LKSDCSHYCVEGCHCDAGYVLNGKSCILP 1422
C C+ GY G C+ P
Sbjct: 2641 ------------CECEVGY--GGGLCMEP 2655
Score = 545 bits (1403), Expect = e-154
Identities = 355/1201 (29%), Positives = 549/1201 (45%), Gaps = 57/1201 (4%)
Query: 587 TQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVP 646
T T ST +CP + Y C +CP +C S C C EGC CN GF+ S + C+
Sbjct: 1034 TTTSRSSTERCPPNARYESC--ACPASCKSPRPS--CGPLCREGCVCNPGFLFSDNHCIQ 1089
Query: 647 LHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCF 706
C C ++ YY G W + NCT C C G V C CG+ VC +++G GC
Sbjct: 1090 ASSCNCFYNNDYYEPGA-EWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCH 1148
Query: 707 PKRET-VCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPER--PEYLEIDINKKKPDAGP 763
P T CL+ + TFDG + F + +Y L + C P + N+++ G
Sbjct: 1149 PYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGV 1208
Query: 764 AWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVV 823
+ L + + + + V + + + GQ+V LP PS + + + ++++ +
Sbjct: 1209 SCLSKVYVTLPESTVTL--LKGRRTLVGGQQVTLPAI-PSKGVFLGASGRFVELQTEFGL 1265
Query: 824 TVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEE 883
V++ LY+ +S+TY GLCG Y+ N+ ++ +G + SW T ++
Sbjct: 1266 RVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQD 1325
Query: 884 ICNGECG--DLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLF 941
+ EC ++ + + DS L CG + D ++ F C V +++ +C+
Sbjct: 1326 E-DQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVD-THGPFETCLLHVKAASFFDSCML 1383
Query: 942 RLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECI-TCTETC 1000
+C G + LC ++ + C++A V PWR FCP+ CP NS + C C +TC
Sbjct: 1384 DMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTC 1443
Query: 1001 ETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIF 1060
+ G C D C E C+C+ G+ L G +C+ RS+CGC W C+
Sbjct: 1444 HSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKEL 1503
Query: 1061 CYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQT 1120
C C ++NR+ C+ C+ E+C ++ G+Y C A+ A+C SG HYLTFDG F
Sbjct: 1504 CVCE-SNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562
Query: 1121 SCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLAL-WVKQVDVTVFGYSIVIHRAYKHT 1179
+C +L S DS+ FVV+A NE+R L + ++K V VTVF SI + R K
Sbjct: 1563 TCTYVLTRPCWSRSQDSY--FVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCK-- 1618
Query: 1180 VLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYG 1239
V++N R+ LP+ L QG++ I V++ T+FGL+V YD + +TVP S G
Sbjct: 1619 VMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCG 1678
Query: 1240 LCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGC---GDRCPSCAKVEGFSK 1296
LCG YN N DD P LA + G +W K + GC G + SC +
Sbjct: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW-KLPESSEPGCFLVGGKPSSCQENSMADA 1737
Query: 1297 VQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQG 1356
+ C+++ N FS+CH V P + +C+ C G C LQ YAS C G
Sbjct: 1738 WNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAG 1797
Query: 1357 ITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHY--CVEGCHCDAGYVL 1414
WRN T C + CPP S Y C S C C++I DC C E C C G++L
Sbjct: 1798 -QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHIL 1856
Query: 1415 NGKSCILPHSCGCYSDGKYYEPKQLFWNSD--CTRRCRCFRRNVIQCDPRQCKSDEECAL 1472
+G SC+ CGC Y P W ++ CTR C C N I C CK ++ C
Sbjct: 1857 SGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWA 1916
Query: 1473 RNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDIS-FQLIINF 1531
+G+ C ++ C G + +FDG+ P C VL +C + F++
Sbjct: 1917 LDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKH 1976
Query: 1532 DKWSAPNLTI-ISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGL-ATKIYSSEGFLV 1589
+K + VY I + Q+ + + V +N QV +P I+ + + SS + +
Sbjct: 1977 EKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSI 2036
Query: 1590 IDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQ 1649
++ +Q+ ++G ++++I I KVCG+CGNFN + D+ + + S
Sbjct: 2037 VNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVN 2096
Query: 1650 SWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLL- 1708
SWK + + PSC L + + Q+ G C + D++ + C L
Sbjct: 2097 SWK-----DKDIDPSCQSLLVDEQQIPAE----QQENPSGNC-RAADLRRAREKCEAALR 2146
Query: 1709 -----------DPLPFYESCYLDGCYSHKKFQ-LCGSLAAYGEACRSFGILSTEWIEKEN 1756
D PF C C +Q LC +L A+G C+S G+ W
Sbjct: 2147 APVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSF 2206
Query: 1757 C 1757
C
Sbjct: 2207 C 2207
Score = 209 bits (533), Expect = 2e-53
Identities = 127/455 (27%), Positives = 202/455 (44%), Gaps = 41/455 (9%)
Query: 1367 SCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCG 1426
S T CPPN+ YESC C C + R C C EGC C+ G++ + CI SC
Sbjct: 1039 SSTERCPPNARYESCA--CPASCKSPR--PSCGPLCREGCVCNPGFLFSDNHCIQASSCN 1094
Query: 1427 CYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFS-TKTS 1485
C+ + YYEP +++ +CT CRC+ + ++C QC + C L+NG GC T+
Sbjct: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154
Query: 1486 YCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPV 1545
CL G + TFDG F C ++L+ C D F++ ++ ++ +S V
Sbjct: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKV 1214
Query: 1546 YFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNV 1605
Y + E + + V G QV +P I + +S F+ + T +++ ++G
Sbjct: 1215 YVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQ 1274
Query: 1606 IKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSC 1665
+ +++S K+CGLCGN++G+ +D++ L G P L SW+T+ + + C
Sbjct: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ----EC 1330
Query: 1666 NELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGC-YS 1724
+ Q + CD+ M G G+C +L D G F+ C + F++SC LD C +
Sbjct: 1331 QKYQVVN-SPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
Query: 1725 HKKFQLCGSLAAYGEACRSFGILSTEWIEKENCS---------GVVEDPC--------VG 1767
+ LC ++ C+ G W E C + PC G
Sbjct: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSG 1449
Query: 1768 ADCPNR---TCELGNG----------RELCGCIEP 1789
C +R CE G R CGC+ P
Sbjct: 1450 MFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 638 bits (1646), Expect = 0.0
Identities = 436/1499 (29%), Positives = 679/1499 (45%), Gaps = 78/1499 (5%)
Query: 274 WDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVE-TSTCVVFGEPHYHT 332
W NCT CRC + + CQ + C + VC+ K + C T+TC+V+G+PHY T
Sbjct: 1108 WFSPNCTEHCRCWP-GSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVT 1166
Query: 333 FDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILI 392
FDG F F G C Y+LA+ C S+ PFF V AKNE + VS + ++ V + + +
Sbjct: 1167 FDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTL 1225
Query: 393 PKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGS 452
KG R V +LP G V + SG ++T+FGL V +DG ++V +
Sbjct: 1226 LKGR--RTLVGGQQVTLPAIPSKG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSST 1282
Query: 453 YINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRV-YHADWKCDSGCVDNCTQCD 511
Y CGLCGNY+ N +D L+ DG PA +LG SW+ D +C V N CD
Sbjct: 1283 YSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCD 1342
Query: 512 AATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAY 571
++ ++ G +CG L T GP C V +F SC+ D+C + LLC +
Sbjct: 1343 SSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTM 1402
Query: 572 ALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGC 631
CQ G + WR C + CP S YS+C CPDTC + C+ C E C
Sbjct: 1403 TTTCQDAGHAVKPWREPHFC--PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEAC 1460
Query: 632 ECNQGFVLSTSQCVPLHKCGCDFD-GHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTC 690
ECN GFVLS +C+P +CGC G Y+ +GE W C C+CE + C C
Sbjct: 1461 ECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGE-RWYKPGCKELCVCESNNRIRCQPWRC 1519
Query: 691 GSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYL 750
+ E C +DG GC + C S + TFDGA + F +Y L + C R +
Sbjct: 1520 RAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDS 1579
Query: 751 EIDINKKKPDAG----PAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKL 806
++ + G ++++ + + V D + + + +V LNG V LP + G++
Sbjct: 1580 YFVVSATNENRGGILEVSYIKAVHVTVFDLSISL--LRGCKVMLNGHRVALPVWLAQGRV 1637
Query: 807 EIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGK 866
I + N + + + V+Y L+ + + ++Y GLCG YN N+ D+ P+ K
Sbjct: 1638 TIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697
Query: 867 CTDNLAVFLESWTTFEEICNG--ECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFL 924
+ +W E G G +C +S + ++ C I+ +P F
Sbjct: 1698 LAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKN---CAILINP-QGPFS 1753
Query: 925 ECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLEC 984
+CH VV + + +C+ C + G+ + LC S+ YAS C A + WR FCP+ C
Sbjct: 1754 QCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRC 1812
Query: 985 PENSHFEECIT-CTETCETLTLGPICVDS--CSEGCQCDEGYALLGSQCVTRSECGC-NF 1040
P S + C + C +TC ++ C + C+E C+C +G+ L G+ CV +CGC +
Sbjct: 1813 PPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDP 1872
Query: 1041 EGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASC 1100
G E ++ + C C CS N + C CK ++ C GL C+A C
Sbjct: 1873 AGSYHPVGERWYTENTCTRLCTCS-VHNNITCFQSTCKPNQICWALDGLLRCRASGVGVC 1931
Query: 1101 IVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSL-ALWVK 1159
+ G HY++FDG +C L+L P+ + P F ++AK+E + A +
Sbjct: 1932 QLPGESHYVSFDGSNHSIPDACTLVLVKV-CHPAM-ALPFFKISAKHEKEEGGTEAFRLH 1989
Query: 1160 QVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVY 1219
+V + ++ + + + H VL+NS+++ LP +++ S + +V G++V +
Sbjct: 1990 EVYIDIYDAQVTLQKG--HRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF 2047
Query: 1220 DWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKR--DTFC 1277
D L I +P + G+CG +N +D+L MP +A+S +EF SW + D C
Sbjct: 2048 DGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSC 2107
Query: 1278 QVGCGDRCPSCAKVE----GFSKVQQLCSLIPNQNAA-----FSKCHSKVNPTFFYKNCL 1328
Q D A+ + G + L AA +++C S+++ T F +C
Sbjct: 2108 QSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCA 2167
Query: 1329 FDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPR 1388
C GG Q C LQ + +TCQ+QG+ WRN + C + CP S Y +C+ C P
Sbjct: 2168 NTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPS 2227
Query: 1389 CAAIRLKSDCSHY---CVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW-NSD 1444
C + + + + C EGC C GYVL+ C+ CGC P W +S
Sbjct: 2228 CWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSG 2287
Query: 1445 CTRRCRCFRRNVIQCDPRQCKSDEECALR--NGVRGCFSTKTSYCLAAGGGVFRTFDGAF 1502
CT +C C IQC +C S C L N C S K+ C G + TFDG
Sbjct: 2288 CTEKCVC-TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFS 2346
Query: 1503 LRFPANCAFVLSTICQKLPD-ISFQLIINFDKWSAPNLTI-----ISPVYFYINEEQILI 1556
R +VL LP+ + L+ +K P +I I+ VY Y ++ +
Sbjct: 2347 YRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGY----KVQL 2402
Query: 1557 NDRNTVKVNGTQVNVPFITG--LATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERL 1614
+ VN ++ VP+ L ++ +LV D ++ + + G IS+
Sbjct: 2403 QAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDF--ELVVSFGGRKNAVISLPSMY 2460
Query: 1615 QNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKT---NGMQKRPLAPSCNE---- 1667
+ V GLCGN++ + +D + G + SW+ + + + P A E
Sbjct: 2461 EGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQG 2520
Query: 1668 ----LQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGC 1722
L+ + C + C L D +G F C+ + P PF E C LD C
Sbjct: 2521 AELGLRTGLQVSECSPEQLASNSTQA-CRVLADPQGPFAACHQTVAPEPFQEHCVLDLC 2578
Score = 559 bits (1440), Expect = e-158
Identities = 375/1294 (28%), Positives = 592/1294 (45%), Gaps = 112/1294 (8%)
Query: 247 FKVDGKEIDPANGCTS---RGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYE 303
F + G E P + C G + + GE W C C C + NN I CQ C E
Sbjct: 1466 FVLSGLECIPRSQCGCLHPAGSYFKVGER-WYKPGCKELCVC-ESNNRIRCQPWRCRAQE 1523
Query: 304 VCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSV 363
C + + C A +TC G+PHY TFDG L HF G+C Y+L R C S +F V
Sbjct: 1524 FCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVV 1583
Query: 364 EAKNEHRRGSA-VSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQ 422
A NE+R G VS++K + V V I + +G +V +N +LPV L G V I
Sbjct: 1584 SATNENRGGILEVSYIKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRL 1641
Query: 423 SGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMS 482
S + T+FGL V +DG H ++VP SY CGLCGNYN N LDD LRPD + A
Sbjct: 1642 SSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGD 1701
Query: 483 VLDLGESWRVYHADWKCDSGCV---DNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGT 539
+ LG +W++ + + GC + C + A + + C L GP +C
Sbjct: 1702 SMQLGAAWKLPESS---EPGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQ 1757
Query: 540 VVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPS 599
VV P + SCV+ C + + T LC+++QAYA +C G WR +T C ++CP
Sbjct: 1758 VVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFC--PMRCPP 1814
Query: 600 FSHYSVCTSSCPDTCSDLTASRNC--ATPCTEGCECNQGFVLSTSQCVPLHKCGC-DFDG 656
S YS C+S CPDTCS + R+C A PC E CEC +G +LS + CVPL +CGC D G
Sbjct: 1815 GSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAG 1874
Query: 657 HYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLS 716
Y+ +GE ++ CT C C ++ CF TC ++C DG C VC L
Sbjct: 1875 SYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLP 1934
Query: 717 QNQVLHTFDGASYAFPSEFSYTLLKTCPERP--EYLEIDINKKKPDAGPAWLRGLRILVA 774
+FDG++++ P + L+K C + +I +K + G R + +
Sbjct: 1935 GESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYID 1994
Query: 775 DQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLY 834
+ ++ V +N ++V LP + + + + V K V V++ LL
Sbjct: 1995 IYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLE 2054
Query: 835 IRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLL- 893
I + TTY+ G+CG +N DE +P+ + ++ + F+ SW ++ + C LL
Sbjct: 2055 IEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWK--DKDIDPSCQSLLV 2112
Query: 894 ----------KACNNDSELLKFYRSRSRC-GIINDPSNSSFLECHGVVNVTAYYRTCLFR 942
+ + + R+R +C + P + +C +++T + C
Sbjct: 2113 DEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAP---VWAQCASRIDLTPFLVDCANT 2169
Query: 943 LCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECI-TCTETCE 1001
LC+ GG LC ++ + + C++ ++ WR FCPLECP S + C+ +C+ +C
Sbjct: 2170 LCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCW 2229
Query: 1002 TL---TLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGC-NFEGHQLATNETFWVDLDC 1057
L G +C+EGC C GY L +CV RS+CGC + G + ++ WV C
Sbjct: 2230 DLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKS-WVSSGC 2288
Query: 1058 QIFCYCSGTDNRVHCETIPCKDDEYCM--EEGGLYYCQARTDASCIVSGYGHYLTFDGFP 1115
C C+G + C C +C + C + C V G YLTFDGF
Sbjct: 2289 TEKCVCTG--GAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFS 2346
Query: 1116 FDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRA 1175
+ Q +L T + +V +N+ P ++++++V TV+GY + +
Sbjct: 2347 YRLQGRMTYVLIKTVD-VLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAG 2405
Query: 1176 YKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQN 1235
+ ++VN++++ +P + + + + +G + + TDF L V + + I++P +
Sbjct: 2406 LE--LVVNNQKMAVPYRPNE-HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEG 2462
Query: 1236 STYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSW-VKRDTF----------------CQ 1278
GLCG Y+ N +D+ +P G L ++N FG SW VK + +
Sbjct: 2463 LVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAE 2522
Query: 1279 VG--CGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGG 1336
+G G + C+ + S Q C ++ + F+ CH V P F ++C+ D C
Sbjct: 2523 LGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLC---- 2578
Query: 1337 AVQTACSWLQNYASTCQT-QGITVTGWRNYTSCTVTCPPNSHYESCVSVCQP-RCAAIR- 1393
+A + CQ G V+ + + T P +CQP R +R
Sbjct: 2579 ---SAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPS--------ILCQPGRPRGLRG 2627
Query: 1394 -LKSDCSHYCVEGCHCDAGYVLNGKSCILPH------SCGCYSDGKYYEPKQLFWNSDCT 1446
L+ + + C+ H CGC S+G YY+ F DC+
Sbjct: 2628 PLRGRLRQH--------------PRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCS 2673
Query: 1447 RRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCF 1480
+RC C ++ C+P C++ E C L N +GCF
Sbjct: 2674 QRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCF 2707
Score = 545 bits (1403), Expect = e-154
Identities = 355/1201 (29%), Positives = 549/1201 (45%), Gaps = 57/1201 (4%)
Query: 587 TQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVP 646
T T ST +CP + Y C +CP +C S C C EGC CN GF+ S + C+
Sbjct: 1034 TTTSRSSTERCPPNARYESC--ACPASCKSPRPS--CGPLCREGCVCNPGFLFSDNHCIQ 1089
Query: 647 LHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCF 706
C C ++ YY G W + NCT C C G V C CG+ VC +++G GC
Sbjct: 1090 ASSCNCFYNNDYYEPGA-EWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCH 1148
Query: 707 PKRET-VCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPER--PEYLEIDINKKKPDAGP 763
P T CL+ + TFDG + F + +Y L + C P + N+++ G
Sbjct: 1149 PYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGV 1208
Query: 764 AWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVV 823
+ L + + + + V + + + GQ+V LP PS + + + ++++ +
Sbjct: 1209 SCLSKVYVTLPESTVTL--LKGRRTLVGGQQVTLPAI-PSKGVFLGASGRFVELQTEFGL 1265
Query: 824 TVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEE 883
V++ LY+ +S+TY GLCG Y+ N+ ++ +G + SW T ++
Sbjct: 1266 RVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQD 1325
Query: 884 ICNGECG--DLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLF 941
+ EC ++ + + DS L CG + D ++ F C V +++ +C+
Sbjct: 1326 E-DQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVD-THGPFETCLLHVKAASFFDSCML 1383
Query: 942 RLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECI-TCTETC 1000
+C G + LC ++ + C++A V PWR FCP+ CP NS + C C +TC
Sbjct: 1384 DMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTC 1443
Query: 1001 ETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIF 1060
+ G C D C E C+C+ G+ L G +C+ RS+CGC W C+
Sbjct: 1444 HSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKEL 1503
Query: 1061 CYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQT 1120
C C ++NR+ C+ C+ E+C ++ G+Y C A+ A+C SG HYLTFDG F
Sbjct: 1504 CVCE-SNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562
Query: 1121 SCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLAL-WVKQVDVTVFGYSIVIHRAYKHT 1179
+C +L S DS+ FVV+A NE+R L + ++K V VTVF SI + R K
Sbjct: 1563 TCTYVLTRPCWSRSQDSY--FVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCK-- 1618
Query: 1180 VLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYG 1239
V++N R+ LP+ L QG++ I V++ T+FGL+V YD + +TVP S G
Sbjct: 1619 VMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCG 1678
Query: 1240 LCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGC---GDRCPSCAKVEGFSK 1296
LCG YN N DD P LA + G +W K + GC G + SC +
Sbjct: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW-KLPESSEPGCFLVGGKPSSCQENSMADA 1737
Query: 1297 VQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQG 1356
+ C+++ N FS+CH V P + +C+ C G C LQ YAS C G
Sbjct: 1738 WNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAG 1797
Query: 1357 ITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHY--CVEGCHCDAGYVL 1414
WRN T C + CPP S Y C S C C++I DC C E C C G++L
Sbjct: 1798 -QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHIL 1856
Query: 1415 NGKSCILPHSCGCYSDGKYYEPKQLFWNSD--CTRRCRCFRRNVIQCDPRQCKSDEECAL 1472
+G SC+ CGC Y P W ++ CTR C C N I C CK ++ C
Sbjct: 1857 SGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWA 1916
Query: 1473 RNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDIS-FQLIINF 1531
+G+ C ++ C G + +FDG+ P C VL +C + F++
Sbjct: 1917 LDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKH 1976
Query: 1532 DKWSAPNLTI-ISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGL-ATKIYSSEGFLV 1589
+K + VY I + Q+ + + V +N QV +P I+ + + SS + +
Sbjct: 1977 EKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSI 2036
Query: 1590 IDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQ 1649
++ +Q+ ++G ++++I I KVCG+CGNFN + D+ + + S
Sbjct: 2037 VNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVN 2096
Query: 1650 SWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLL- 1708
SWK + + PSC L + + Q+ G C + D++ + C L
Sbjct: 2097 SWK-----DKDIDPSCQSLLVDEQQIPAE----QQENPSGNC-RAADLRRAREKCEAALR 2146
Query: 1709 -----------DPLPFYESCYLDGCYSHKKFQ-LCGSLAAYGEACRSFGILSTEWIEKEN 1756
D PF C C +Q LC +L A+G C+S G+ W
Sbjct: 2147 APVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSF 2206
Query: 1757 C 1757
C
Sbjct: 2207 C 2207
Score = 209 bits (533), Expect = 2e-53
Identities = 127/455 (27%), Positives = 202/455 (44%), Gaps = 41/455 (9%)
Query: 1367 SCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCG 1426
S T CPPN+ YESC C C + R C C EGC C+ G++ + CI SC
Sbjct: 1039 SSTERCPPNARYESCA--CPASCKSPR--PSCGPLCREGCVCNPGFLFSDNHCIQASSCN 1094
Query: 1427 CYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFS-TKTS 1485
C+ + YYEP +++ +CT CRC+ + ++C QC + C L+NG GC T+
Sbjct: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154
Query: 1486 YCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPV 1545
CL G + TFDG F C ++L+ C D F++ ++ ++ +S V
Sbjct: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKV 1214
Query: 1546 YFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNV 1605
Y + E + + V G QV +P I + +S F+ + T +++ ++G
Sbjct: 1215 YVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQ 1274
Query: 1606 IKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSC 1665
+ +++S K+CGLCGN++G+ +D++ L G P L SW+T+ + + C
Sbjct: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ----EC 1330
Query: 1666 NELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGC-YS 1724
+ Q + CD+ M G G+C +L D G F+ C + F++SC LD C +
Sbjct: 1331 QKYQVVN-SPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
Query: 1725 HKKFQLCGSLAAYGEACRSFGILSTEWIEKENCS---------GVVEDPC--------VG 1767
+ LC ++ C+ G W E C + PC G
Sbjct: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSG 1449
Query: 1768 ADCPNR---TCELGNG----------RELCGCIEP 1789
C +R CE G R CGC+ P
Sbjct: 1450 MFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
Score = 151 bits (381), Expect = 8e-36
Identities = 129/488 (26%), Positives = 191/488 (39%), Gaps = 56/488 (11%)
Query: 274 WDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCE--PKGKFFYCSAVETSTCVVFGEPHYH 331
W CT KC C I C + C C+ C + ++ C V+G+P Y
Sbjct: 2283 WVSSGCTEKCVCT--GGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYL 2340
Query: 332 TFDGFLFHFQGSCAYLLARQC-LQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKI 390
TFDGF + QG Y+L + + + VE +N+ + +++E+ V GYK+
Sbjct: 2341 TFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV 2400
Query: 391 LIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVP 450
+ G + VN+ ++P + +++ G + TDF L+V+F G+ A IS+P
Sbjct: 2401 QLQAGL--ELVVNNQKMAVPYRPN-EHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLP 2457
Query: 451 GSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHAD-------------- 496
Y GLCGNY+KN +D + P G ++ G SW V D
Sbjct: 2458 SMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEE 2517
Query: 497 -WKCDSGCVDNCTQCDAATEALYFGSDY-CGFLNKTDGPLWECGTVVDPTAFVHSCVYDL 554
+ G + + E L S C L GP C V P F CV DL
Sbjct: 2518 GQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDL 2577
Query: 555 CSVRD---NGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCP 611
CS +D L CQ + + + S H S + P
Sbjct: 2578 CSAQDPREQEELRCQVLSGHGV------------------------SSRYHISELYDTLP 2613
Query: 612 DTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANC 671
R P + L PL CGC +G YY +G F T +C
Sbjct: 2614 SILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSSF-LTEDC 2672
Query: 672 TVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLS--QNQVLHTFDGASY 729
+ +C C + C +C +GEVC + + QGCFP E+ CL + QN GA++
Sbjct: 2673 SQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFP--ESPCLQNPCQNDGQCREQGATF 2730
Query: 730 AFPSEFSY 737
E Y
Sbjct: 2731 TCECEVGY 2738
>gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1472
Score = 560 bits (1444), Expect = e-159
Identities = 312/906 (34%), Positives = 455/906 (50%), Gaps = 25/906 (2%)
Query: 294 CQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCL 353
C+ C+ + C+ G C A T+ C G+PHY TFDG + G+C+Y + C
Sbjct: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 564
Query: 354 QTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTL 413
+ +LP FSVEAKNEHR VS+V ++V + + + +G G V V++ + LPV+L
Sbjct: 565 EDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSL 624
Query: 414 DLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFL 473
G +++YQSG VE FGL+VT+D ++S+P + + CGLCGNYN +P DDFL
Sbjct: 625 SEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 684
Query: 474 RPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGP 533
PDG A ++ SW++ D+ C+ GC +NC C Y G CG L K DGP
Sbjct: 685 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 744
Query: 534 LWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVS 593
C +DP F+ CVYDLC V LC+ + AYA C LGI +GDWR+ C
Sbjct: 745 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC-- 802
Query: 594 TVQCPSFSHYSVCTSSCPDTCSDLTASRNCA-TPCTEGCECNQGFVLSTSQCVPLHKCGC 652
+ CP+ S Y +C +CP +C+ A NC+ PC EGC C GFV S CVP CGC
Sbjct: 803 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 862
Query: 653 DFDGHYYTMGEFFWATANCTVQCLCEEG-GDVYCFNK-TCGSGEVCAVEDGYQGCFPKRE 710
F G G+ WA C +C C V C +K +C +GE C+V++G GC+P R
Sbjct: 863 TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 922
Query: 711 TVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPER---PEYLEIDINKKKPDAGPAWLR 767
C S + +FDG + F +Y L+ +C + P + + N+ + ++ R
Sbjct: 923 GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTR 982
Query: 768 GLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQY 827
+R+ +V + +V ++ LPF G+++++R V + +TV Y
Sbjct: 983 AVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTY 1042
Query: 828 SDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNG 887
+ ++ ++Y GLCG +N + +D+ L G N F SW EE G
Sbjct: 1043 DWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ--EETRPG 1100
Query: 888 ----ECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRL 943
E GD K DS + + +S++ CGI+ DP F ECH ++ R C++
Sbjct: 1101 CGATEPGDCPKL---DSLVAQQLQSKNECGILADP-KGPFRECHSKLDPQGAVRDCVYDR 1156
Query: 944 CQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC-ITCTETCET 1002
C G LCD++A YA+AC+ A V PWR+ + CPL CP +SH+E C C +C
Sbjct: 1157 CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGD 1216
Query: 1003 LTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCY 1062
L + C C EGC CDEG+AL G C+ + CGC +G +TF+ C C+
Sbjct: 1217 LPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCH 1276
Query: 1063 CSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSC 1122
C V CE+ C E C GG C A ++C SG HY TFDG FDF +C
Sbjct: 1277 CQ-EGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC 1335
Query: 1123 PLILC-TTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVI-HRAYKHTV 1180
+L T G+RP +F V +N + + V V +++ + R +K TV
Sbjct: 1336 VYVLAQTCGTRP---GLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 1392
Query: 1181 LVNSER 1186
+ E+
Sbjct: 1393 RADGEQ 1398
Score = 474 bits (1220), Expect = e-133
Identities = 278/903 (30%), Positives = 408/903 (45%), Gaps = 28/903 (3%)
Query: 685 CFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCP 744
C C +G+ C V G GC + VC + TFDG Y SYT+++ C
Sbjct: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 564
Query: 745 ERPEYLEIDINKKKPDAGP---AWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFH 801
E + K G +++ + + V + V ++ Q LP
Sbjct: 565 EDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSL 624
Query: 802 PSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFC 861
G+L +Y++ VE + V Y L + L + + GLCG YN + +D+F
Sbjct: 625 SEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 684
Query: 862 LPNGKCTDNLAVFLESWTTFEE--ICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPS 919
P+G + F SW + +C C + AC + Y CG++
Sbjct: 685 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQA--QHYEGDRLCGMLTK-L 741
Query: 920 NSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDF 979
+ F CH ++ + C++ LC GG LC ++ YA AC + VG WR+
Sbjct: 742 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 801
Query: 980 CPLECPENSHFEEC-ITCTETCETLTLGPICVDS-CSEGCQCDEGYALLGSQCVTRSECG 1037
CPL CP NS +E C C +C C C EGC C G+ G CV S CG
Sbjct: 802 CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCG 861
Query: 1038 CNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHC-ETIPCKDDEYCMEEGGLYYCQART 1096
C F+G QLA + W D CQ C C+G ++V C + C E C + GL C
Sbjct: 862 CTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDR 921
Query: 1097 DASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLAL 1156
+C SG HY++FDG FDF +C +L GS + + P F V +NE R
Sbjct: 922 FGTCQGSGDPHYVSFDGRRFDFMGTCTYLL--VGSCGQNAALPAFRVLVENEHRGSQTVS 979
Query: 1157 WVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLK 1216
+ + V V G + + R Y VLV+ YLP + G++ +F G VV TDFGL
Sbjct: 980 YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLT 1039
Query: 1217 VVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTF 1276
V YDW ++ VP S + GLCG +NG+P DDL + G A++ FG SW +
Sbjct: 1040 VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEET-- 1097
Query: 1277 CQVGCGDRCPS-CAKVEGFSKVQQL-----CSLIPNQNAAFSKCHSKVNPTFFYKNCLFD 1330
+ GCG P C K++ QQL C ++ + F +CHSK++P ++C++D
Sbjct: 1098 -RPGCGATEPGDCPKLDSLV-AQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYD 1155
Query: 1331 SCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCA 1390
C+ G C L YA+ CQ G TV WR+ C ++CPP+SHYE+C C C
Sbjct: 1156 RCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCG 1215
Query: 1391 AIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW-NSDCTRRC 1449
+ + C C EGC CD G+ L+G+SC+ SCGC G Y+ P Q F+ C C
Sbjct: 1216 DLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLC 1275
Query: 1450 RCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANC 1509
C ++ C+ C E C G GC + +S C A+G + TFDG F C
Sbjct: 1276 HCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC 1335
Query: 1510 AFVLSTICQKLPDI-SFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRN---TVKVN 1565
+VL+ C P + F ++ W +++ + + + + R TV+ +
Sbjct: 1336 VYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVRAD 1395
Query: 1566 GTQ 1568
G Q
Sbjct: 1396 GEQ 1398
Score = 355 bits (911), Expect = 3e-97
Identities = 211/698 (30%), Positives = 322/698 (46%), Gaps = 21/698 (3%)
Query: 1072 CETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGS 1131
CE + C + C GG C A + A C G HY TFDG +D +C + S
Sbjct: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 564
Query: 1132 RPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPL 1191
D+ P F V AKNE R +V V V + +S+ + R VLV+++R LP+
Sbjct: 565 E--DDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
Query: 1192 KLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDD 1251
L +G++ ++ G VVE FGL V YDW L++++P Q+ GLCG YNG+P DD
Sbjct: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
Query: 1252 LEMPMGLLASSVNEFGQSWV--KRDTFCQVGCGDRCPSCAKVEG-FSKVQQLCSLIPNQN 1308
P G LA EF SW D C+ GC + CP+C + + +LC ++ +
Sbjct: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 742
Query: 1309 AAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSC 1368
F+ CH ++P F + C++D C+ GG + C L YA C GI+V WR+ +C
Sbjct: 743 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 802
Query: 1369 TVTCPPNSHYESCVSVCQPRCAAIRLKSDCS-HYCVEGCHCDAGYVLNGKSCILPHSCGC 1427
++CP NS YE C C C S+CS CVEGC C G+V +G +C+ SCGC
Sbjct: 803 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 862
Query: 1428 YSDGKYYEPKQLFWNSD-CTRRCRCF-RRNVIQC-DPRQCKSDEECALRNGVRGCFSTKT 1484
G P Q W + C RRC C + + C D + C + E C+++NG+ GC+ +
Sbjct: 863 TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 922
Query: 1485 SYCLAAGGGVFRTFDGAFLRFPANCAFVLSTIC-QKLPDISFQLIINFDKWSAPNLTIIS 1543
C +G + +FDG F C ++L C Q +F++++ + + ++
Sbjct: 923 GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTR 982
Query: 1544 PVYFYINEEQILINDR--NTVKVNGTQVNVPFITGLA-TKIYSSEGFLVIDTSPDIQIYY 1600
V ++ + V V+ +PF +++ V+ T + + Y
Sbjct: 983 AVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTY 1042
Query: 1601 NGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRP 1660
+ + + +CGLCGNFNGD DD G +++ SW +
Sbjct: 1043 DWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSW------QEE 1096
Query: 1661 LAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLD 1720
P C + + D++ Q++Q C L D KG F+ C+ LDP C D
Sbjct: 1097 TRPGCGATEPGDCPKL-DSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYD 1155
Query: 1721 GC-YSHKKFQLCGSLAAYGEACRSFGILSTEWIEKENC 1757
C + LC +LA Y AC++ G W +E C
Sbjct: 1156 RCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELC 1193
Score = 342 bits (878), Expect = 2e-93
Identities = 183/512 (35%), Positives = 250/512 (48%), Gaps = 9/512 (1%)
Query: 239 VNVPGRWAFKVDGKEIDPAN--GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQE 296
V +PG F G PA+ GCT +G L G+ W D C +C C +++ C++
Sbjct: 842 VCLPG---FVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 898
Query: 297 -ASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQT 355
SC E C + C TC G+PHY +FDG F F G+C YLL C Q
Sbjct: 899 KQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQN 958
Query: 356 SSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDL 415
++LP F V +NEHR VS+ + + VE G K+ + + G+V V+D++ LP
Sbjct: 959 AALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAAD 1018
Query: 416 GTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRP 475
G V++++ G V TDFGL VT+D + VP SY + CGLCGN+N +P DD
Sbjct: 1019 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1078
Query: 476 DGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLW 535
G A + L G SW+ C + +C + D+ + CG L GP
Sbjct: 1079 GGGQAANALAFGNSWQ-EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFR 1137
Query: 536 ECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTV 595
EC + +DP V CVYD C + LC A+ YA CQA G + WR++ C +
Sbjct: 1138 ECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELC--PL 1195
Query: 596 QCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFD 655
CP SHY C+ CP +C DL C + C EGC C++GF LS C+PL CGC
Sbjct: 1196 SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQ 1255
Query: 656 GHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLL 715
G Y+ G+ F+ C C C+EGG V C + +CG E C G GC + C
Sbjct: 1256 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQA 1315
Query: 716 SQNQVLHTFDGASYAFPSEFSYTLLKTCPERP 747
S + TFDG + F Y L +TC RP
Sbjct: 1316 SGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP 1347
Score = 129 bits (324), Expect = 3e-29
Identities = 91/340 (26%), Positives = 142/340 (41%), Gaps = 41/340 (12%)
Query: 1459 CDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQ 1518
C+ QC + + C + G GC + T+ C A G + TFDG C++ + +C
Sbjct: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 564
Query: 1519 K---LPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPF-I 1574
+ LP S + + + V Y + + + V V+ + +P +
Sbjct: 565 EDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSL 624
Query: 1575 TGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYV 1634
+ ++Y S V++ + + Y+ + +S+ R Q++VCGLCGN+NGD DD++
Sbjct: 625 SEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 684
Query: 1635 TLRGKPVVSSVVLAQSWK--------TNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQ 1686
T G +V A SWK +G Q P+C Q Y +
Sbjct: 685 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNN--CPACTPGQAQHY------------E 730
Query: 1687 GDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGC-YSHKKFQLCGSLAAYGEACRSFG 1745
GD C LT + G F C+ LDP PF E C D C ++ LC L+AY +AC G
Sbjct: 731 GDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELG 790
Query: 1746 ILSTEWIEKENCSGVVEDPCVGADCPNRTCELGNGRELCG 1785
I +W NC +C + ELCG
Sbjct: 791 ISVGDWRSPANCP--------------LSCPANSRYELCG 816
Score = 94.4 bits (233), Expect = 1e-18
Identities = 46/132 (34%), Positives = 69/132 (52%), Gaps = 1/132 (0%)
Query: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVE 318
GC +G + G+ F+ C C C + + C+ +SC P+E C+P G C AV
Sbjct: 1251 GCVHQGTYHPPGQTFYPGPGCDSLCHCQE-GGLVSCESSSCGPHEACQPSGGSLGCVAVG 1309
Query: 319 TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWV 378
+STC G+PHY TFDG F F G+C Y+LA+ C L F+V +N VS
Sbjct: 1310 SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVT 1369
Query: 379 KELSVEVNGYKI 390
+ ++V+V + +
Sbjct: 1370 RVITVQVANFTL 1381
>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 300 bits (768), Expect = 1e-80
Identities = 280/1119 (25%), Positives = 458/1119 (40%), Gaps = 139/1119 (12%)
Query: 322 CVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHR-RGSAVSWVKE 380
C +G+ H+ TFDG ++F G+C+Y+ A+ C P ++V N + GS S +
Sbjct: 64 CKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLE--PRYTVWVHNSPKCLGSVYSCYRS 121
Query: 381 LSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFD 440
+S+ + + + G +K N + +LP T +G + I + V+T FG + +D
Sbjct: 122 ISLFFSNQEEIRIYGH--EIKKNGISLTLPQT--IGQIFIEKLADYILVKTTFGFSLAWD 177
Query: 441 GQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCD 500
G + + + +CGLCGNYN DDF+ + SW V D D
Sbjct: 178 GISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPD---D 234
Query: 501 SGCV-------DNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYD 553
+ CV + C+ A EA++F C L P C +DP ++ SCV D
Sbjct: 235 TKCVLTPSDFPNPCSSGMPAFEAIFF---KCQIL--LQFPFLSCHEYIDPYLYIASCVND 289
Query: 554 LCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDT 613
LC D+ T C+A YA C G PI DWR + SF H C S CP T
Sbjct: 290 LCKTDDDET-YCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRD-CISCCPPT 347
Query: 614 CSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTV 673
C+ C +GC C G V+ C+ L C C F G Y++G CT
Sbjct: 348 CTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKI--EQECT- 404
Query: 674 QCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPS 733
+C+C GG C + C C + + TFDG Y+F
Sbjct: 405 ECVC-VGGVWNCTEQDC-------------------PVQCSVVGDSHFTTFDGRHYSFIG 444
Query: 734 EFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQ 793
Y L+K + + + + + G L+ + +++ D K +G GQ
Sbjct: 445 MCQYILVKGTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGR-----GGQ 499
Query: 794 EVELP--FFHPSGKLEIYRNKNSTTVESK---GVVTVQYSDIGLLYIRLSTTYFNCTGGL 848
+ P F+ +G +EI + +S + K G+ + D +YI+L++ + T GL
Sbjct: 500 ILTSPNQGFNLNGIVEI-QTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGL 558
Query: 849 CGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRS 908
CG +N N D+F P+G + +W ++ CN + + + +
Sbjct: 559 CGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGY--- 615
Query: 909 RSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNAD 968
+ C +I+ F CH ++ YY+ C C+ G S LC+++A YA C
Sbjct: 616 AAHCDVIH---QELFAPCHIYISPGLYYQLCRHDACKCG--SSCLCNALAHYAYLCGQHG 670
Query: 969 VEVGPWRTYDFCPLECPENSHFEECIT-CTETCETLTLGPICVDSCSEGCQCDEG--YAL 1025
V + FC + C + + C + C +C +L+ C D C+EGC C EG Y
Sbjct: 671 VPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYED 730
Query: 1026 LGSQCVTRSECGCNFEG-------------------------HQLATNETFWVDLDCQIF 1060
+ CV C C++ G +LAT + + + +
Sbjct: 731 TLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEY 790
Query: 1061 CYCSGTD-----NRVHCET--------IPCKDDEYCME---------EGGLYYC-QARTD 1097
C D V+CET C C+ G++ C
Sbjct: 791 FDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCP 850
Query: 1098 ASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALW 1157
A C + G HY +FDG +D+ + C + L + + DS V A+N+ + +
Sbjct: 851 AVCTIYGDRHYYSFDGLEYDYISDCQVFLI----KSADDS--DISVIAQNKKCFDNDIVC 904
Query: 1158 VKQVDVTVFGYSIVIH-RAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVE-TDFGL 1215
K V ++V I ++ YK +L K ++ G+++VV + +
Sbjct: 905 SKSVLISVGDTEIYLNDTPYKQ----KQSGFFLENK---STYQLWKAGYYIVVYFPEKDI 957
Query: 1216 KVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDT 1275
+++D KT + I V +N GLCG ++ +D+ L + FG SW
Sbjct: 958 TILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQ- 1016
Query: 1276 FCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCID- 1334
C+ P A F ++ CS++ + F+ C + ++ T F KNC D+C
Sbjct: 1017 -CESPDETIKPCEAHQNKFPYAKKECSIL--YSDIFASCRNVIDVTSFAKNCHEDTCNCN 1073
Query: 1335 -GGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTC 1372
GG + C+ + YA C +GI++ WR+ T C++ C
Sbjct: 1074 LGGDCECLCTSIAAYAYKCCQEGISI-HWRSSTVCSLDC 1111
Score = 250 bits (638), Expect = 1e-65
Identities = 270/1182 (22%), Positives = 448/1182 (37%), Gaps = 175/1182 (14%)
Query: 664 FFWATANCTVQCL----CEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQ 719
FF + +C +CL C + G C G C + R+ +C
Sbjct: 15 FFSPSGSCPYECLNGAFCSKTGTCDC-QIFQALGTRCQIIPNMGN---GRDGICKTWGQY 70
Query: 720 VLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAW--LRGLRILVADQ- 776
TFDG Y FP SY K C + + ++ G + R + + ++Q
Sbjct: 71 HFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCYRSISLFFSNQE 130
Query: 777 EVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIR 836
E++I G E+K NG + LP G++ I + + V++ ++ + I +Y++
Sbjct: 131 EIRIYG---HEIKKNGISLTLP--QTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLK 185
Query: 837 LSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESW---TTFEEICNGECGDLL 893
LS + + GLCG YN SD+F + T+++A+F SW T + C D
Sbjct: 186 LSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFP 245
Query: 894 KACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESEL 953
C+ S + F +C I+ FL CH ++ Y +C+ LC++ +E+
Sbjct: 246 NPCS--SGMPAFEAIFFKCQIL---LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET-Y 299
Query: 954 CDSVARYASACKNADVEVGPWR-TYDFCPLECPENSHFEECITCTETCETLTLGPICVDS 1012
C + YA AC +A + WR + C +C ++ +CI+C T T C+ S
Sbjct: 300 CRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCP--PTCTFEKQCLGS 357
Query: 1013 ---CSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNR 1069
C +GC C +G + C++ C C F G Y G+
Sbjct: 358 NLHCLDGCYCPDGLVMDNGTCISLENCPCGFHG-----------------LAYSVGSKIE 400
Query: 1070 VHCETIPCKDDEYCMEEGGLYYC-QARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCT 1128
C C+ GG++ C + C V G H+ TFDG + F C IL
Sbjct: 401 QECTE--------CVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK 452
Query: 1129 -TGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAY-KHTVLVNSER 1186
TG KF +T + + +L L V + ++++ + K L +
Sbjct: 453 GTGK-------DKFTITLQKAPCEQNLGL------VCLQSITLILEDDFNKQVTLGRGGQ 499
Query: 1187 LYLPLKLG---QGKINIFSF-GFHVVVETDFGLKVVY--DWKTFLSITVPRSMQNSTYGL 1240
+ G G + I + ++++T FGLK+++ D + + I + + + T GL
Sbjct: 500 ILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWKRRTLGL 558
Query: 1241 CGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTF---CQVGCGDRCPSCAKVEGFSKV 1297
CG +NGN DD P G++ + +W T V D C + G++
Sbjct: 559 CGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGYA-- 616
Query: 1298 QQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGI 1357
C +I + F+ CH ++P +Y+ C D+C G + C+ L +YA C G+
Sbjct: 617 -AHCDVIHQE--LFAPCHIYISPGLYYQLCRHDACKCGSS--CLCNALAHYAYLCGQHGV 671
Query: 1358 TVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAG--YVLN 1415
+ + C V C Y C S C C ++ CS C EGC+C G Y
Sbjct: 672 PIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDT 731
Query: 1416 GKSCILPHSCGCYSDGKYYEPKQLF----------------------------------- 1440
C+ C C+ G Y+P +L
Sbjct: 732 LNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYF 791
Query: 1441 -----------WNSDCTRRCRCFRRNVIQCDPRQCKSDEECA---LRNGVRGC-FSTKTS 1485
+C C N C S CA R G+ C + +
Sbjct: 792 DCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPA 851
Query: 1486 YCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPV 1545
C G + +FDG + ++C L + D +I K ++ V
Sbjct: 852 VCTIYGDRHYYSFDGLEYDYISDCQVFL---IKSADDSDISVIAQNKKCFDNDIVCSKSV 908
Query: 1546 YFYINEEQILINDR-NTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSP--DIQIYYNG 1602
+ + +I +ND K +G F+ +T G+ ++ P DI I ++
Sbjct: 909 LISVGDTEIYLNDTPYKQKQSGF-----FLENKSTYQLWKAGYYIVVYFPEKDITILWDR 963
Query: 1603 FNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQK--RP 1660
I I + + +NK+ GLCGNF+ ++D T V ++ V SW +
Sbjct: 964 KTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQCESPDET 1023
Query: 1661 LAP-SCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYL 1719
+ P ++ +F C ++ F C ++D F ++C+
Sbjct: 1024 IKPCEAHQNKFPYAKKECSILY----------------SDIFASCRNVIDVTSFAKNCHE 1067
Query: 1720 DGCYSHKKFQ---LCGSLAAYGEACRSFGILSTEWIEKENCS 1758
D C + LC S+AAY C GI S W CS
Sbjct: 1068 DTCNCNLGGDCECLCTSIAAYAYKCCQEGI-SIHWRSSTVCS 1108
Score = 86.7 bits (213), Expect = 2e-16
Identities = 73/295 (24%), Positives = 118/295 (40%), Gaps = 29/295 (9%)
Query: 1487 CLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVY 1546
C G F TFDG + FP NC+++ + C L + W + + VY
Sbjct: 64 CKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEP-------RYTVWVHNSPKCLGSVY 116
Query: 1547 --------FYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQI 1598
F+ N+E+I I +K NG + +P G I ++++ T+ +
Sbjct: 117 SCYRSISLFFSNQEEIRIYGHE-IKKNGISLTLPQTIGQIF-IEKLADYILVKTTFGFSL 174
Query: 1599 YYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSW--KTNGM 1656
++G + I + +SE + K CGLCGN+N +DD++ L+ + A SW +T
Sbjct: 175 AWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDD 234
Query: 1657 QKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYES 1716
K L PS S + + + C L F C+ +DP + S
Sbjct: 235 TKCVLTPSDFPNPCSSGMPAFEAIFFK-------CQILLQFP--FLSCHEYIDPYLYIAS 285
Query: 1717 CYLDGCYSHKKFQLCGSLAAYGEACRSFGILSTEWIEK-ENCSGVVEDPCVGADC 1770
C D C + C + Y AC G +W + C+ +D V DC
Sbjct: 286 CVNDLCKTDDDETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDC 340
Score = 81.3 bits (199), Expect = 1e-14
Identities = 90/369 (24%), Positives = 152/369 (41%), Gaps = 43/369 (11%)
Query: 705 CFPKRETVC---LLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDA 761
C P+ E C +LS+ ++ TFDG + A S SY L++ E + I K +
Sbjct: 1431 CCPEWECPCRCSMLSELSII-TFDGNNAALYSMASYILVRI---PGEIIVAHIEKCSMNQ 1486
Query: 762 GPAW------LRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNST 815
P+ + L + ++ + + A +V+++ V LPF S +L I + +
Sbjct: 1487 APSGRISGLCFKKLNVTTPIHKIIVNRL-ARKVEVDSIVVPLPF--SSQELSIEDSGSMY 1543
Query: 816 TVESKGVVTVQYSDI-GLLYIRLSTTY--FNCTGGLCGFYNANASDEFCLPNGKCTDNL- 871
+ + + +++S + G++ I + + T GLCG N + D+ + NG N+
Sbjct: 1544 VITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNME 1603
Query: 872 --AVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGV 929
+F+ESW EI + + N +E S+C I+ + F+ CH
Sbjct: 1604 DIGLFIESW----EIEKSFEVTMRRPVRNCTE-----HDCSQC--IDLLNRRIFIPCHDK 1652
Query: 930 VNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSH 989
V+ + E CD+++ Y + C D+ + WRT D+C L CPE
Sbjct: 1653 VSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGKE 1708
Query: 990 FEECITCTETCETLTLGPICVDSC---SEGCQCDEGYAL---LGSQCVTRSECGCNFEGH 1043
++ C+ E L SC E C C G L +QC+ EC C
Sbjct: 1709 YQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECACTDSED 1768
Query: 1044 QLATNETFW 1052
Q T W
Sbjct: 1769 QPRTAGEIW 1777
Score = 80.5 bits (197), Expect = 2e-14
Identities = 83/329 (25%), Positives = 134/329 (40%), Gaps = 40/329 (12%)
Query: 277 LNCTVKCRCLDFNNEIYCQEAS-CSPYEVCEP----KGKF----FYCSAVETSTCVVFGE 327
+NC C L N C +S C VC P +G F + C AV C ++G+
Sbjct: 805 VNCETTCANLAMN--FTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAV----CTIYGD 858
Query: 328 PHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNG 387
HY++FDG + + C L + + SV A+N+ + + K + + V
Sbjct: 859 RHYYSFDGLEYDYISDCQVFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGD 914
Query: 388 YKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAV---ETDFGLLVTFDGQHY 444
+I + Y + + + + T +++++G V E D +L +D +
Sbjct: 915 TEIYLNDTPYKQKQSGFFLE------NKSTYQLWKAGYYIVVYFPEKDITIL--WDRKTT 966
Query: 445 ASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCV 504
I V + N GLCGN++K +D + + G+SW A +C+S
Sbjct: 967 IHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW----ALGQCESP-D 1021
Query: 505 DNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNG--T 562
+ C+A + C L C V+D T+F +C D C+ G
Sbjct: 1022 ETIKPCEAHQNKFPYAKKECSIL--YSDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCE 1079
Query: 563 LLCQAIQAYALVCQALGIPIGDWRTQTGC 591
LC +I AYA C GI I WR+ T C
Sbjct: 1080 CLCTSIAAYAYKCCQEGISI-HWRSSTVC 1107
Score = 75.9 bits (185), Expect = 4e-13
Identities = 73/306 (23%), Positives = 122/306 (39%), Gaps = 30/306 (9%)
Query: 1156 LWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGL 1215
L K+++VT + I+++R + V + + +PL +++I G V+ T GL
Sbjct: 1495 LCFKKLNVTTPIHKIIVNRLARK---VEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGL 1551
Query: 1216 KVVYDWKTFL---SITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFG---QS 1269
+ + T + ++ + T GLCG N +PDDDL M G + +++ + G +S
Sbjct: 1552 IIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIES 1611
Query: 1270 WVKRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLF 1329
W +F +V +C + + + L F CH KV+P F +
Sbjct: 1612 WEIEKSF-EVTMRRPVRNCTEHDCSQCIDLL------NRRIFIPCHDKVSPEDFCEKMWI 1664
Query: 1330 DSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRC 1389
+ C L Y + C I + WR C+++CP Y+ CV C+ R
Sbjct: 1665 NYTY---FWNYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEART 1720
Query: 1390 AAIRL---KSDCSHYCVEGCHCDAGYVL---NGKSCILPHSCGCYSDGKYYEPKQLFWN- 1442
+ + C + E C C G VL + CI C C WN
Sbjct: 1721 CLNQWFYGHTSCLN-LREDCVCKVGTVLHRPHSAQCIPEKECACTDSEDQPRTAGEIWNG 1779
Query: 1443 --SDCT 1446
+CT
Sbjct: 1780 GIDECT 1785
Score = 72.4 bits (176), Expect = 4e-12
Identities = 100/431 (23%), Positives = 157/431 (36%), Gaps = 62/431 (14%)
Query: 278 NCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFL 337
+C + R + N++I C E C C + E TFDG
Sbjct: 1416 DCGFRGRPVQVNSDICCPEWECP-------------------CRCSMLSELSIITFDGNN 1456
Query: 338 FHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWV--KELSVEVNGYKILIPKG 395
+Y+L R + + + +S + K+L+V +KI++ +
Sbjct: 1457 AALYSMASYILVR--IPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRL 1514
Query: 396 SYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQ------HYASISV 449
+ +V+V+ +V LP + + I SG + T GL++ + H+
Sbjct: 1515 AR-KVEVDSIVVPLPFSSQ--ELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFN 1571
Query: 450 PGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLG---ESWRVYHADWKCDSGCVDN 506
SY CG+C N++P DD +G ++ D+G ESW + + V N
Sbjct: 1572 LSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRN 1628
Query: 507 CTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQ 566
CT+ D S LN+ C V P F C + C
Sbjct: 1629 CTEHDC--------SQCIDLLNRRI--FIPCHDKVSPEDF---CEKMWINYTYFWNYECD 1675
Query: 567 AIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPD-TCSD--LTASRNC 623
A+ AY +C I I WRT C ++ CP Y C C TC + +C
Sbjct: 1676 ALSAYVALCNKFDICI-QWRTPDYC--SLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC 1732
Query: 624 ATPCTEGCECNQGFVLS---TSQCVPLHKCGC-DFDGHYYTMGEFFWATANCTVQCLCEE 679
E C C G VL ++QC+P +C C D + T GE + + C E
Sbjct: 1733 LN-LREDCVCKVGTVLHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLE 1791
Query: 680 GGDVYCFNKTC 690
G + C
Sbjct: 1792 NGSIIPIEPDC 1802
>gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 300 bits (768), Expect = 1e-80
Identities = 280/1119 (25%), Positives = 458/1119 (40%), Gaps = 139/1119 (12%)
Query: 322 CVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHR-RGSAVSWVKE 380
C +G+ H+ TFDG ++F G+C+Y+ A+ C P ++V N + GS S +
Sbjct: 64 CKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLE--PRYTVWVHNSPKCLGSVYSCYRS 121
Query: 381 LSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFD 440
+S+ + + + G +K N + +LP T +G + I + V+T FG + +D
Sbjct: 122 ISLFFSNQEEIRIYGH--EIKKNGISLTLPQT--IGQIFIEKLADYILVKTTFGFSLAWD 177
Query: 441 GQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCD 500
G + + + +CGLCGNYN DDF+ + SW V D D
Sbjct: 178 GISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPD---D 234
Query: 501 SGCV-------DNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYD 553
+ CV + C+ A EA++F C L P C +DP ++ SCV D
Sbjct: 235 TKCVLTPSDFPNPCSSGMPAFEAIFF---KCQIL--LQFPFLSCHEYIDPYLYIASCVND 289
Query: 554 LCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDT 613
LC D+ T C+A YA C G PI DWR + SF H C S CP T
Sbjct: 290 LCKTDDDET-YCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRD-CISCCPPT 347
Query: 614 CSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTV 673
C+ C +GC C G V+ C+ L C C F G Y++G CT
Sbjct: 348 CTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKI--EQECT- 404
Query: 674 QCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPS 733
+C+C GG C + C C + + TFDG Y+F
Sbjct: 405 ECVC-VGGVWNCTEQDC-------------------PVQCSVVGDSHFTTFDGRHYSFIG 444
Query: 734 EFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQ 793
Y L+K + + + + + G L+ + +++ D K +G GQ
Sbjct: 445 MCQYILVKGTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGR-----GGQ 499
Query: 794 EVELP--FFHPSGKLEIYRNKNSTTVESK---GVVTVQYSDIGLLYIRLSTTYFNCTGGL 848
+ P F+ +G +EI + +S + K G+ + D +YI+L++ + T GL
Sbjct: 500 ILTSPNQGFNLNGIVEI-QTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGL 558
Query: 849 CGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRS 908
CG +N N D+F P+G + +W ++ CN + + + +
Sbjct: 559 CGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGY--- 615
Query: 909 RSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNAD 968
+ C +I+ F CH ++ YY+ C C+ G S LC+++A YA C
Sbjct: 616 AAHCDVIH---QELFAPCHIYISPGLYYQLCRHDACKCG--SSCLCNALAHYAYLCGQHG 670
Query: 969 VEVGPWRTYDFCPLECPENSHFEECIT-CTETCETLTLGPICVDSCSEGCQCDEG--YAL 1025
V + FC + C + + C + C +C +L+ C D C+EGC C EG Y
Sbjct: 671 VPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYED 730
Query: 1026 LGSQCVTRSECGCNFEG-------------------------HQLATNETFWVDLDCQIF 1060
+ CV C C++ G +LAT + + + +
Sbjct: 731 TLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEY 790
Query: 1061 CYCSGTD-----NRVHCET--------IPCKDDEYCME---------EGGLYYC-QARTD 1097
C D V+CET C C+ G++ C
Sbjct: 791 FDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCP 850
Query: 1098 ASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALW 1157
A C + G HY +FDG +D+ + C + L + + DS V A+N+ + +
Sbjct: 851 AVCTIYGDRHYYSFDGLEYDYISDCQVFLI----KSADDS--DISVIAQNKKCFDNDIVC 904
Query: 1158 VKQVDVTVFGYSIVIH-RAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVE-TDFGL 1215
K V ++V I ++ YK +L K ++ G+++VV + +
Sbjct: 905 SKSVLISVGDTEIYLNDTPYKQ----KQSGFFLENK---STYQLWKAGYYIVVYFPEKDI 957
Query: 1216 KVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDT 1275
+++D KT + I V +N GLCG ++ +D+ L + FG SW
Sbjct: 958 TILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQ- 1016
Query: 1276 FCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCID- 1334
C+ P A F ++ CS++ + F+ C + ++ T F KNC D+C
Sbjct: 1017 -CESPDETIKPCEAHQNKFPYAKKECSIL--YSDIFASCRNVIDVTSFAKNCHEDTCNCN 1073
Query: 1335 -GGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTC 1372
GG + C+ + YA C +GI++ WR+ T C++ C
Sbjct: 1074 LGGDCECLCTSIAAYAYKCCQEGISI-HWRSSTVCSLDC 1111
Score = 250 bits (638), Expect = 1e-65
Identities = 270/1182 (22%), Positives = 448/1182 (37%), Gaps = 175/1182 (14%)
Query: 664 FFWATANCTVQCL----CEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQ 719
FF + +C +CL C + G C G C + R+ +C
Sbjct: 15 FFSPSGSCPYECLNGAFCSKTGTCDC-QIFQALGTRCQIIPNMGN---GRDGICKTWGQY 70
Query: 720 VLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAW--LRGLRILVADQ- 776
TFDG Y FP SY K C + + ++ G + R + + ++Q
Sbjct: 71 HFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCYRSISLFFSNQE 130
Query: 777 EVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIR 836
E++I G E+K NG + LP G++ I + + V++ ++ + I +Y++
Sbjct: 131 EIRIYG---HEIKKNGISLTLP--QTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLK 185
Query: 837 LSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESW---TTFEEICNGECGDLL 893
LS + + GLCG YN SD+F + T+++A+F SW T + C D
Sbjct: 186 LSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFP 245
Query: 894 KACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESEL 953
C+ S + F +C I+ FL CH ++ Y +C+ LC++ +E+
Sbjct: 246 NPCS--SGMPAFEAIFFKCQIL---LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET-Y 299
Query: 954 CDSVARYASACKNADVEVGPWR-TYDFCPLECPENSHFEECITCTETCETLTLGPICVDS 1012
C + YA AC +A + WR + C +C ++ +CI+C T T C+ S
Sbjct: 300 CRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCP--PTCTFEKQCLGS 357
Query: 1013 ---CSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNR 1069
C +GC C +G + C++ C C F G Y G+
Sbjct: 358 NLHCLDGCYCPDGLVMDNGTCISLENCPCGFHG-----------------LAYSVGSKIE 400
Query: 1070 VHCETIPCKDDEYCMEEGGLYYC-QARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCT 1128
C C+ GG++ C + C V G H+ TFDG + F C IL
Sbjct: 401 QECTE--------CVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK 452
Query: 1129 -TGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAY-KHTVLVNSER 1186
TG KF +T + + +L L V + ++++ + K L +
Sbjct: 453 GTGK-------DKFTITLQKAPCEQNLGL------VCLQSITLILEDDFNKQVTLGRGGQ 499
Query: 1187 LYLPLKLG---QGKINIFSF-GFHVVVETDFGLKVVY--DWKTFLSITVPRSMQNSTYGL 1240
+ G G + I + ++++T FGLK+++ D + + I + + + T GL
Sbjct: 500 ILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWKRRTLGL 558
Query: 1241 CGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTF---CQVGCGDRCPSCAKVEGFSKV 1297
CG +NGN DD P G++ + +W T V D C + G++
Sbjct: 559 CGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGYA-- 616
Query: 1298 QQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGI 1357
C +I + F+ CH ++P +Y+ C D+C G + C+ L +YA C G+
Sbjct: 617 -AHCDVIHQE--LFAPCHIYISPGLYYQLCRHDACKCGSS--CLCNALAHYAYLCGQHGV 671
Query: 1358 TVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAG--YVLN 1415
+ + C V C Y C S C C ++ CS C EGC+C G Y
Sbjct: 672 PIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDT 731
Query: 1416 GKSCILPHSCGCYSDGKYYEPKQLF----------------------------------- 1440
C+ C C+ G Y+P +L
Sbjct: 732 LNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYF 791
Query: 1441 -----------WNSDCTRRCRCFRRNVIQCDPRQCKSDEECA---LRNGVRGC-FSTKTS 1485
+C C N C S CA R G+ C + +
Sbjct: 792 DCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPA 851
Query: 1486 YCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPV 1545
C G + +FDG + ++C L + D +I K ++ V
Sbjct: 852 VCTIYGDRHYYSFDGLEYDYISDCQVFL---IKSADDSDISVIAQNKKCFDNDIVCSKSV 908
Query: 1546 YFYINEEQILINDR-NTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSP--DIQIYYNG 1602
+ + +I +ND K +G F+ +T G+ ++ P DI I ++
Sbjct: 909 LISVGDTEIYLNDTPYKQKQSGF-----FLENKSTYQLWKAGYYIVVYFPEKDITILWDR 963
Query: 1603 FNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQK--RP 1660
I I + + +NK+ GLCGNF+ ++D T V ++ V SW +
Sbjct: 964 KTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQCESPDET 1023
Query: 1661 LAP-SCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYL 1719
+ P ++ +F C ++ F C ++D F ++C+
Sbjct: 1024 IKPCEAHQNKFPYAKKECSILY----------------SDIFASCRNVIDVTSFAKNCHE 1067
Query: 1720 DGCYSHKKFQ---LCGSLAAYGEACRSFGILSTEWIEKENCS 1758
D C + LC S+AAY C GI S W CS
Sbjct: 1068 DTCNCNLGGDCECLCTSIAAYAYKCCQEGI-SIHWRSSTVCS 1108
Score = 86.7 bits (213), Expect = 2e-16
Identities = 73/295 (24%), Positives = 118/295 (40%), Gaps = 29/295 (9%)
Query: 1487 CLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVY 1546
C G F TFDG + FP NC+++ + C L + W + + VY
Sbjct: 64 CKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEP-------RYTVWVHNSPKCLGSVY 116
Query: 1547 --------FYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQI 1598
F+ N+E+I I +K NG + +P G I ++++ T+ +
Sbjct: 117 SCYRSISLFFSNQEEIRIYGHE-IKKNGISLTLPQTIGQIF-IEKLADYILVKTTFGFSL 174
Query: 1599 YYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSW--KTNGM 1656
++G + I + +SE + K CGLCGN+N +DD++ L+ + A SW +T
Sbjct: 175 AWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDD 234
Query: 1657 QKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYES 1716
K L PS S + + + C L F C+ +DP + S
Sbjct: 235 TKCVLTPSDFPNPCSSGMPAFEAIFFK-------CQILLQFP--FLSCHEYIDPYLYIAS 285
Query: 1717 CYLDGCYSHKKFQLCGSLAAYGEACRSFGILSTEWIEK-ENCSGVVEDPCVGADC 1770
C D C + C + Y AC G +W + C+ +D V DC
Sbjct: 286 CVNDLCKTDDDETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDC 340
Score = 80.9 bits (198), Expect = 1e-14
Identities = 90/369 (24%), Positives = 152/369 (41%), Gaps = 43/369 (11%)
Query: 705 CFPKRETVC---LLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDA 761
C P+ E C +LS+ ++ TFDG + A S SY L++ E + I K +
Sbjct: 1431 CCPEWECPCRCSMLSELSII-TFDGNNAALYSMASYILVRI---PGEIIVAHIEKCSMNQ 1486
Query: 762 GPAW------LRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNST 815
P+ + L + ++ + + A +V+++ V LPF S +L I + +
Sbjct: 1487 APSGRISGLCFKKLNVTTPIHKIIVNRL-ARKVEVDSIVVPLPF--SSQELSIEDSGSMY 1543
Query: 816 TVESKGVVTVQYSDI-GLLYIRLSTTY--FNCTGGLCGFYNANASDEFCLPNGKCTDNL- 871
+ + + +++S + G++ I + + T GLCG N + D+ + NG N+
Sbjct: 1544 VITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNME 1603
Query: 872 --AVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGV 929
+F+ESW EI + + N +E S+C I+ + F+ CH
Sbjct: 1604 DIGLFIESW----EIEKSFEVTMRRPVRNCTE-----HDCSQC--IDLLNRRIFIPCHDK 1652
Query: 930 VNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSH 989
V+ + E CD+++ Y + C D+ + WRT D+C L CPE
Sbjct: 1653 VSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGKE 1708
Query: 990 FEECITCTETCETLTLGPICVDSC---SEGCQCDEGYAL---LGSQCVTRSECGCNFEGH 1043
++ C+ E L SC E C C G L +QC+ EC C
Sbjct: 1709 YQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSED 1768
Query: 1044 QLATNETFW 1052
Q T W
Sbjct: 1769 QPRTAGEIW 1777
Score = 80.5 bits (197), Expect = 2e-14
Identities = 83/329 (25%), Positives = 134/329 (40%), Gaps = 40/329 (12%)
Query: 277 LNCTVKCRCLDFNNEIYCQEAS-CSPYEVCEP----KGKF----FYCSAVETSTCVVFGE 327
+NC C L N C +S C VC P +G F + C AV C ++G+
Sbjct: 805 VNCETTCANLAMN--FTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAV----CTIYGD 858
Query: 328 PHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNG 387
HY++FDG + + C L + + SV A+N+ + + K + + V
Sbjct: 859 RHYYSFDGLEYDYISDCQVFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGD 914
Query: 388 YKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAV---ETDFGLLVTFDGQHY 444
+I + Y + + + + T +++++G V E D +L +D +
Sbjct: 915 TEIYLNDTPYKQKQSGFFLE------NKSTYQLWKAGYYIVVYFPEKDITIL--WDRKTT 966
Query: 445 ASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCV 504
I V + N GLCGN++K +D + + G+SW A +C+S
Sbjct: 967 IHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW----ALGQCESP-D 1021
Query: 505 DNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNG--T 562
+ C+A + C L C V+D T+F +C D C+ G
Sbjct: 1022 ETIKPCEAHQNKFPYAKKECSIL--YSDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCE 1079
Query: 563 LLCQAIQAYALVCQALGIPIGDWRTQTGC 591
LC +I AYA C GI I WR+ T C
Sbjct: 1080 CLCTSIAAYAYKCCQEGISI-HWRSSTVC 1107
Score = 75.5 bits (184), Expect = 5e-13
Identities = 72/306 (23%), Positives = 122/306 (39%), Gaps = 30/306 (9%)
Query: 1156 LWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGL 1215
L K+++VT + I+++R + V + + +PL +++I G V+ T GL
Sbjct: 1495 LCFKKLNVTTPIHKIIVNRLARK---VEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGL 1551
Query: 1216 KVVYDWKTFL---SITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFG---QS 1269
+ + T + ++ + T GLCG N +PDDDL M G + +++ + G +S
Sbjct: 1552 IIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIES 1611
Query: 1270 WVKRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLF 1329
W +F +V +C + + + L F CH KV+P F +
Sbjct: 1612 WEIEKSF-EVTMRRPVRNCTEHDCSQCIDLL------NRRIFIPCHDKVSPEDFCEKMWI 1664
Query: 1330 DSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRC 1389
+ C L Y + C I + WR C+++CP Y+ CV C+ R
Sbjct: 1665 NYTY---FWNYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEART 1720
Query: 1390 AAIRL---KSDCSHYCVEGCHCDAGYVL---NGKSCILPHSCGCYSDGKYYEPKQLFWN- 1442
+ + C + E C C G +L + CI C C WN
Sbjct: 1721 CLNQWFYGHTSCLN-LREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNG 1779
Query: 1443 --SDCT 1446
+CT
Sbjct: 1780 GIDECT 1785
Score = 72.0 bits (175), Expect = 6e-12
Identities = 99/431 (22%), Positives = 157/431 (36%), Gaps = 62/431 (14%)
Query: 278 NCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFL 337
+C + R + N++I C E C C + E TFDG
Sbjct: 1416 DCGFRGRPVQVNSDICCPEWECP-------------------CRCSMLSELSIITFDGNN 1456
Query: 338 FHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWV--KELSVEVNGYKILIPKG 395
+Y+L R + + + +S + K+L+V +KI++ +
Sbjct: 1457 AALYSMASYILVR--IPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRL 1514
Query: 396 SYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQ------HYASISV 449
+ +V+V+ +V LP + + I SG + T GL++ + H+
Sbjct: 1515 AR-KVEVDSIVVPLPFSSQ--ELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFN 1571
Query: 450 PGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLG---ESWRVYHADWKCDSGCVDN 506
SY CG+C N++P DD +G ++ D+G ESW + + V N
Sbjct: 1572 LSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRN 1628
Query: 507 CTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQ 566
CT+ D S LN+ C V P F C + C
Sbjct: 1629 CTEHDC--------SQCIDLLNRRI--FIPCHDKVSPEDF---CEKMWINYTYFWNYECD 1675
Query: 567 AIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPD-TCSD--LTASRNC 623
A+ AY +C I I WRT C ++ CP Y C C TC + +C
Sbjct: 1676 ALSAYVALCNKFDICI-QWRTPDYC--SLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC 1732
Query: 624 ATPCTEGCECNQGFVLS---TSQCVPLHKCGC-DFDGHYYTMGEFFWATANCTVQCLCEE 679
E C C G +L ++QC+P +C C D + T GE + + C E
Sbjct: 1733 LN-LREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLE 1791
Query: 680 GGDVYCFNKTC 690
G + C
Sbjct: 1792 NGSIIPIEPDC 1802
>gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sapiens]
Length = 2250
Score = 300 bits (768), Expect = 1e-80
Identities = 280/1119 (25%), Positives = 458/1119 (40%), Gaps = 139/1119 (12%)
Query: 322 CVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHR-RGSAVSWVKE 380
C +G+ H+ TFDG ++F G+C+Y+ A+ C P ++V N + GS S +
Sbjct: 64 CKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLE--PRYTVWVHNSPKCLGSVYSCYRS 121
Query: 381 LSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFD 440
+S+ + + + G +K N + +LP T +G + I + V+T FG + +D
Sbjct: 122 ISLFFSNQEEIRIYGH--EIKKNGISLTLPQT--IGQIFIEKLADYILVKTTFGFSLAWD 177
Query: 441 GQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCD 500
G + + + +CGLCGNYN DDF+ + SW V D D
Sbjct: 178 GISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPD---D 234
Query: 501 SGCV-------DNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYD 553
+ CV + C+ A EA++F C L P C +DP ++ SCV D
Sbjct: 235 TKCVLTPSDFPNPCSSGMPAFEAIFF---KCQIL--LQFPFLSCHEYIDPYLYIASCVND 289
Query: 554 LCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDT 613
LC D+ T C+A YA C G PI DWR + SF H C S CP T
Sbjct: 290 LCKTDDDET-YCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRD-CISCCPPT 347
Query: 614 CSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTV 673
C+ C +GC C G V+ C+ L C C F G Y++G CT
Sbjct: 348 CTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKI--EQECT- 404
Query: 674 QCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPS 733
+C+C GG C + C C + + TFDG Y+F
Sbjct: 405 ECVC-VGGVWNCTEQDC-------------------PVQCSVVGDSHFTTFDGRHYSFIG 444
Query: 734 EFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQ 793
Y L+K + + + + + G L+ + +++ D K +G GQ
Sbjct: 445 MCQYILVKGTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGR-----GGQ 499
Query: 794 EVELP--FFHPSGKLEIYRNKNSTTVESK---GVVTVQYSDIGLLYIRLSTTYFNCTGGL 848
+ P F+ +G +EI + +S + K G+ + D +YI+L++ + T GL
Sbjct: 500 ILTSPNQGFNLNGIVEI-QTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGL 558
Query: 849 CGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRS 908
CG +N N D+F P+G + +W ++ CN + + + +
Sbjct: 559 CGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGY--- 615
Query: 909 RSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNAD 968
+ C +I+ F CH ++ YY+ C C+ G S LC+++A YA C
Sbjct: 616 AAHCDVIH---QELFAPCHIYISPGLYYQLCRHDACKCG--SSCLCNALAHYAYLCGQHG 670
Query: 969 VEVGPWRTYDFCPLECPENSHFEECIT-CTETCETLTLGPICVDSCSEGCQCDEG--YAL 1025
V + FC + C + + C + C +C +L+ C D C+EGC C EG Y
Sbjct: 671 VPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYED 730
Query: 1026 LGSQCVTRSECGCNFEG-------------------------HQLATNETFWVDLDCQIF 1060
+ CV C C++ G +LAT + + + +
Sbjct: 731 TLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEY 790
Query: 1061 CYCSGTD-----NRVHCET--------IPCKDDEYCME---------EGGLYYC-QARTD 1097
C D V+CET C C+ G++ C
Sbjct: 791 FDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCP 850
Query: 1098 ASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALW 1157
A C + G HY +FDG +D+ + C + L + + DS V A+N+ + +
Sbjct: 851 AVCTIYGDRHYYSFDGLEYDYISDCQVFLI----KSADDS--DISVIAQNKKCFDNDIVC 904
Query: 1158 VKQVDVTVFGYSIVIH-RAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVE-TDFGL 1215
K V ++V I ++ YK +L K ++ G+++VV + +
Sbjct: 905 SKSVLISVGDTEIYLNDTPYKQ----KQSGFFLENK---STYQLWKAGYYIVVYFPEKDI 957
Query: 1216 KVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDT 1275
+++D KT + I V +N GLCG ++ +D+ L + FG SW
Sbjct: 958 TILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQ- 1016
Query: 1276 FCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCID- 1334
C+ P A F ++ CS++ + F+ C + ++ T F KNC D+C
Sbjct: 1017 -CESPDETIKPCEAHQNKFPYAKKECSIL--YSDIFASCRNVIDVTSFAKNCHEDTCNCN 1073
Query: 1335 -GGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTC 1372
GG + C+ + YA C +GI++ WR+ T C++ C
Sbjct: 1074 LGGDCECLCTSIAAYAYKCCQEGISI-HWRSSTVCSLDC 1111
Score = 250 bits (638), Expect = 1e-65
Identities = 270/1182 (22%), Positives = 448/1182 (37%), Gaps = 175/1182 (14%)
Query: 664 FFWATANCTVQCL----CEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQ 719
FF + +C +CL C + G C G C + R+ +C
Sbjct: 15 FFSPSGSCPYECLNGAFCSKTGTCDC-QIFQALGTRCQIIPNMGN---GRDGICKTWGQY 70
Query: 720 VLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAW--LRGLRILVADQ- 776
TFDG Y FP SY K C + + ++ G + R + + ++Q
Sbjct: 71 HFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCYRSISLFFSNQE 130
Query: 777 EVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIR 836
E++I G E+K NG + LP G++ I + + V++ ++ + I +Y++
Sbjct: 131 EIRIYG---HEIKKNGISLTLP--QTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLK 185
Query: 837 LSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESW---TTFEEICNGECGDLL 893
LS + + GLCG YN SD+F + T+++A+F SW T + C D
Sbjct: 186 LSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFP 245
Query: 894 KACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESEL 953
C+ S + F +C I+ FL CH ++ Y +C+ LC++ +E+
Sbjct: 246 NPCS--SGMPAFEAIFFKCQIL---LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET-Y 299
Query: 954 CDSVARYASACKNADVEVGPWR-TYDFCPLECPENSHFEECITCTETCETLTLGPICVDS 1012
C + YA AC +A + WR + C +C ++ +CI+C T T C+ S
Sbjct: 300 CRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCP--PTCTFEKQCLGS 357
Query: 1013 ---CSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNR 1069
C +GC C +G + C++ C C F G Y G+
Sbjct: 358 NLHCLDGCYCPDGLVMDNGTCISLENCPCGFHG-----------------LAYSVGSKIE 400
Query: 1070 VHCETIPCKDDEYCMEEGGLYYC-QARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCT 1128
C C+ GG++ C + C V G H+ TFDG + F C IL
Sbjct: 401 QECTE--------CVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK 452
Query: 1129 -TGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAY-KHTVLVNSER 1186
TG KF +T + + +L L V + ++++ + K L +
Sbjct: 453 GTGK-------DKFTITLQKAPCEQNLGL------VCLQSITLILEDDFNKQVTLGRGGQ 499
Query: 1187 LYLPLKLG---QGKINIFSF-GFHVVVETDFGLKVVY--DWKTFLSITVPRSMQNSTYGL 1240
+ G G + I + ++++T FGLK+++ D + + I + + + T GL
Sbjct: 500 ILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWKRRTLGL 558
Query: 1241 CGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTF---CQVGCGDRCPSCAKVEGFSKV 1297
CG +NGN DD P G++ + +W T V D C + G++
Sbjct: 559 CGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGYA-- 616
Query: 1298 QQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGI 1357
C +I + F+ CH ++P +Y+ C D+C G + C+ L +YA C G+
Sbjct: 617 -AHCDVIHQE--LFAPCHIYISPGLYYQLCRHDACKCGSS--CLCNALAHYAYLCGQHGV 671
Query: 1358 TVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAG--YVLN 1415
+ + C V C Y C S C C ++ CS C EGC+C G Y
Sbjct: 672 PIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDT 731
Query: 1416 GKSCILPHSCGCYSDGKYYEPKQLF----------------------------------- 1440
C+ C C+ G Y+P +L
Sbjct: 732 LNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYF 791
Query: 1441 -----------WNSDCTRRCRCFRRNVIQCDPRQCKSDEECA---LRNGVRGC-FSTKTS 1485
+C C N C S CA R G+ C + +
Sbjct: 792 DCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPA 851
Query: 1486 YCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPV 1545
C G + +FDG + ++C L + D +I K ++ V
Sbjct: 852 VCTIYGDRHYYSFDGLEYDYISDCQVFL---IKSADDSDISVIAQNKKCFDNDIVCSKSV 908
Query: 1546 YFYINEEQILINDR-NTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSP--DIQIYYNG 1602
+ + +I +ND K +G F+ +T G+ ++ P DI I ++
Sbjct: 909 LISVGDTEIYLNDTPYKQKQSGF-----FLENKSTYQLWKAGYYIVVYFPEKDITILWDR 963
Query: 1603 FNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQK--RP 1660
I I + + +NK+ GLCGNF+ ++D T V ++ V SW +
Sbjct: 964 KTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQCESPDET 1023
Query: 1661 LAP-SCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYL 1719
+ P ++ +F C ++ F C ++D F ++C+
Sbjct: 1024 IKPCEAHQNKFPYAKKECSILY----------------SDIFASCRNVIDVTSFAKNCHE 1067
Query: 1720 DGCYSHKKFQ---LCGSLAAYGEACRSFGILSTEWIEKENCS 1758
D C + LC S+AAY C GI S W CS
Sbjct: 1068 DTCNCNLGGDCECLCTSIAAYAYKCCQEGI-SIHWRSSTVCS 1108
Score = 86.7 bits (213), Expect = 2e-16
Identities = 73/295 (24%), Positives = 118/295 (40%), Gaps = 29/295 (9%)
Query: 1487 CLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVY 1546
C G F TFDG + FP NC+++ + C L + W + + VY
Sbjct: 64 CKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEP-------RYTVWVHNSPKCLGSVY 116
Query: 1547 --------FYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQI 1598
F+ N+E+I I +K NG + +P G I ++++ T+ +
Sbjct: 117 SCYRSISLFFSNQEEIRIYGHE-IKKNGISLTLPQTIGQIF-IEKLADYILVKTTFGFSL 174
Query: 1599 YYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSW--KTNGM 1656
++G + I + +SE + K CGLCGN+N +DD++ L+ + A SW +T
Sbjct: 175 AWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDD 234
Query: 1657 QKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYES 1716
K L PS S + + + C L F C+ +DP + S
Sbjct: 235 TKCVLTPSDFPNPCSSGMPAFEAIFFK-------CQILLQFP--FLSCHEYIDPYLYIAS 285
Query: 1717 CYLDGCYSHKKFQLCGSLAAYGEACRSFGILSTEWIEK-ENCSGVVEDPCVGADC 1770
C D C + C + Y AC G +W + C+ +D V DC
Sbjct: 286 CVNDLCKTDDDETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDC 340
Score = 80.9 bits (198), Expect = 1e-14
Identities = 90/369 (24%), Positives = 152/369 (41%), Gaps = 43/369 (11%)
Query: 705 CFPKRETVC---LLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDA 761
C P+ E C +LS+ ++ TFDG + A S SY L++ E + I K +
Sbjct: 1431 CCPEWECPCRCSMLSELSII-TFDGNNAALYSMASYILVRI---PGEIIVAHIEKCSMNQ 1486
Query: 762 GPAW------LRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNST 815
P+ + L + ++ + + A +V+++ V LPF S +L I + +
Sbjct: 1487 APSGRISGLCFKKLNVTTPIHKIIVNRL-ARKVEVDSIVVPLPF--SSQELSIEDSGSMY 1543
Query: 816 TVESKGVVTVQYSDI-GLLYIRLSTTY--FNCTGGLCGFYNANASDEFCLPNGKCTDNL- 871
+ + + +++S + G++ I + + T GLCG N + D+ + NG N+
Sbjct: 1544 VITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNME 1603
Query: 872 --AVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGV 929
+F+ESW EI + + N +E S+C I+ + F+ CH
Sbjct: 1604 DIGLFIESW----EIEKSFEVTMRRPVRNCTE-----HDCSQC--IDLLNRRIFIPCHDK 1652
Query: 930 VNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSH 989
V+ + E CD+++ Y + C D+ + WRT D+C L CPE
Sbjct: 1653 VSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGKE 1708
Query: 990 FEECITCTETCETLTLGPICVDSC---SEGCQCDEGYAL---LGSQCVTRSECGCNFEGH 1043
++ C+ E L SC E C C G L +QC+ EC C
Sbjct: 1709 YQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSED 1768
Query: 1044 QLATNETFW 1052
Q T W
Sbjct: 1769 QPRTAGEIW 1777
Score = 80.5 bits (197), Expect = 2e-14
Identities = 83/329 (25%), Positives = 134/329 (40%), Gaps = 40/329 (12%)
Query: 277 LNCTVKCRCLDFNNEIYCQEAS-CSPYEVCEP----KGKF----FYCSAVETSTCVVFGE 327
+NC C L N C +S C VC P +G F + C AV C ++G+
Sbjct: 805 VNCETTCANLAMN--FTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAV----CTIYGD 858
Query: 328 PHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNG 387
HY++FDG + + C L + + SV A+N+ + + K + + V
Sbjct: 859 RHYYSFDGLEYDYISDCQVFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGD 914
Query: 388 YKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAV---ETDFGLLVTFDGQHY 444
+I + Y + + + + T +++++G V E D +L +D +
Sbjct: 915 TEIYLNDTPYKQKQSGFFLE------NKSTYQLWKAGYYIVVYFPEKDITIL--WDRKTT 966
Query: 445 ASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCV 504
I V + N GLCGN++K +D + + G+SW A +C+S
Sbjct: 967 IHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW----ALGQCESP-D 1021
Query: 505 DNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNG--T 562
+ C+A + C L C V+D T+F +C D C+ G
Sbjct: 1022 ETIKPCEAHQNKFPYAKKECSIL--YSDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCE 1079
Query: 563 LLCQAIQAYALVCQALGIPIGDWRTQTGC 591
LC +I AYA C GI I WR+ T C
Sbjct: 1080 CLCTSIAAYAYKCCQEGISI-HWRSSTVC 1107
Score = 75.5 bits (184), Expect = 5e-13
Identities = 72/306 (23%), Positives = 122/306 (39%), Gaps = 30/306 (9%)
Query: 1156 LWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGL 1215
L K+++VT + I+++R + V + + +PL +++I G V+ T GL
Sbjct: 1495 LCFKKLNVTTPIHKIIVNRLARK---VEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGL 1551
Query: 1216 KVVYDWKTFL---SITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFG---QS 1269
+ + T + ++ + T GLCG N +PDDDL M G + +++ + G +S
Sbjct: 1552 IIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIES 1611
Query: 1270 WVKRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLF 1329
W +F +V +C + + + L F CH KV+P F +
Sbjct: 1612 WEIEKSF-EVTMRRPVRNCTEHDCSQCIDLL------NRRIFIPCHDKVSPEDFCEKMWI 1664
Query: 1330 DSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRC 1389
+ C L Y + C I + WR C+++CP Y+ CV C+ R
Sbjct: 1665 NYTY---FWNYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEART 1720
Query: 1390 AAIRL---KSDCSHYCVEGCHCDAGYVL---NGKSCILPHSCGCYSDGKYYEPKQLFWN- 1442
+ + C + E C C G +L + CI C C WN
Sbjct: 1721 CLNQWFYGHTSCLN-LREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNG 1779
Query: 1443 --SDCT 1446
+CT
Sbjct: 1780 GIDECT 1785
Score = 72.0 bits (175), Expect = 6e-12
Identities = 99/431 (22%), Positives = 157/431 (36%), Gaps = 62/431 (14%)
Query: 278 NCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFL 337
+C + R + N++I C E C C + E TFDG
Sbjct: 1416 DCGFRGRPVQVNSDICCPEWECP-------------------CRCSMLSELSIITFDGNN 1456
Query: 338 FHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWV--KELSVEVNGYKILIPKG 395
+Y+L R + + + +S + K+L+V +KI++ +
Sbjct: 1457 AALYSMASYILVR--IPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRL 1514
Query: 396 SYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQ------HYASISV 449
+ +V+V+ +V LP + + I SG + T GL++ + H+
Sbjct: 1515 AR-KVEVDSIVVPLPFSSQ--ELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFN 1571
Query: 450 PGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLG---ESWRVYHADWKCDSGCVDN 506
SY CG+C N++P DD +G ++ D+G ESW + + V N
Sbjct: 1572 LSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRN 1628
Query: 507 CTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQ 566
CT+ D S LN+ C V P F C + C
Sbjct: 1629 CTEHDC--------SQCIDLLNRRI--FIPCHDKVSPEDF---CEKMWINYTYFWNYECD 1675
Query: 567 AIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPD-TCSD--LTASRNC 623
A+ AY +C I I WRT C ++ CP Y C C TC + +C
Sbjct: 1676 ALSAYVALCNKFDICI-QWRTPDYC--SLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC 1732
Query: 624 ATPCTEGCECNQGFVLS---TSQCVPLHKCGC-DFDGHYYTMGEFFWATANCTVQCLCEE 679
E C C G +L ++QC+P +C C D + T GE + + C E
Sbjct: 1733 LN-LREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLE 1791
Query: 680 GGDVYCFNKTC 690
G + C
Sbjct: 1792 NGSIIPIEPDC 1802
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 270 bits (690), Expect = 1e-71
Identities = 213/771 (27%), Positives = 314/771 (40%), Gaps = 81/771 (10%)
Query: 319 TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWV 378
T+ C +FG +TFDG ++ F G C+YLLA C + S FS+ + + G VS
Sbjct: 32 TARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS----FSIIG--DFQNGKRVS-- 83
Query: 379 KELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVT 438
LSV + + I G V D S+P G ++G +G +
Sbjct: 84 --LSVYLGEF-FDIHLFVNGTVTQGDQRVSMPYA-SKGLYLETEAGYYKLSGEAYGFVAR 139
Query: 439 FDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK 498
DG + + Y N TCGLCGN+N DDF+ +G D SW + +
Sbjct: 140 IDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQW 199
Query: 499 CDSGCVDNCTQCDAATEALYFGS-DYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSV 557
C+ + + C+ ++ + G + C L T C +VDP FV C LC
Sbjct: 200 CERASPPS-SSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCEKTLCEC 257
Query: 558 RDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDL 617
C A+ YA C G+ + W + C CP+ Y C S C TC L
Sbjct: 258 AGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPV--CPAGMEYRQCVSPCARTCQSL 315
Query: 618 TASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLC 677
+ C C +GC C +G +L CV +C C G Y G N C+C
Sbjct: 316 HINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCN---TCIC 372
Query: 678 EEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSY 737
+ C N+ C GE CL++ +FD + F Y
Sbjct: 373 RNSQWI-CSNEEC-PGE------------------CLVTGQSHFKSFDNRYFTFSGICQY 412
Query: 738 TLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVKL------- 790
L + C + + I+ + D R + V++ G+ S VKL
Sbjct: 413 LLARDCQDHSFSIVIETVQCADDRDAVCTRSV-------TVRLPGLHNSLVKLKHGAGVA 465
Query: 791 -NGQEVELPFFHPSGKLEIYRNKNSTTVESKGV-VTVQYSDIGLLYIRLSTTYFNCTGGL 848
+GQ+V+LP G L I ++ S G + + + G L ++LS Y T GL
Sbjct: 466 MDGQDVQLPLL--KGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGL 523
Query: 849 CGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLK----ACNNDSELLK 904
CG YN N D+F P+G + F +W +G+C DL K C + + +
Sbjct: 524 CGNYNGNQGDDFLTPSGLAEPRVEDFGNAWK-----LHGDCQDLQKQHSDPCALNPRMTR 578
Query: 905 FYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASAC 964
F S C ++ P +F CH V+ Y R C + +C LC ++A YA+AC
Sbjct: 579 F--SEEACAVLTSP---TFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAAC 633
Query: 965 KNADVEVGPWRTYDFCPLECPENSHFEECIT-CTETCETLTL-GPICVDSCSEGCQCDEG 1022
V V WR C L CP+ + +C T C TC +L+ C ++C EGC C G
Sbjct: 634 AGRGVRVA-WREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPG 692
Query: 1023 -YALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHC 1072
Y CV +++C C ++G + F D CYC D +HC
Sbjct: 693 LYMDERGDCVPKAQCPCYYDGEIFQPEDIF---SDHHTMCYCE--DGFMHC 738
Score = 259 bits (661), Expect = 3e-68
Identities = 204/766 (26%), Positives = 314/766 (40%), Gaps = 96/766 (12%)
Query: 713 CLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRIL 772
C L + ++TFDG+ Y+F SY L C +R + D K + +L
Sbjct: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLSVYLGEF--- 91
Query: 773 VADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGL 832
D + + G V Q V +P+ LE + E+ G V + G
Sbjct: 92 -FDIHLFVNGT----VTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVA-RIDGSGN 145
Query: 833 LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFE---------- 882
+ LS YFN T GLCG +N A D+F G T + F SW
Sbjct: 146 FQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERASP 205
Query: 883 --EICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCL 940
CN G++ K +LLK S S F CH +V+ + C
Sbjct: 206 PSSSCNISSGEMQKGLWEQCQLLK--------------STSVFARCHPLVDPEPFVALCE 251
Query: 941 FRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECIT-CTET 999
LC+ G C ++ YA C + + W + C CP + +C++ C T
Sbjct: 252 KTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCART 311
Query: 1000 CETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQI 1059
C++L + +C + C +GC C EG L CV +EC C G +
Sbjct: 312 CQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKR--------------- 356
Query: 1060 FCYCSGTDNRVHCETIPCKDDEY-CMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDF 1118
Y GT C T C++ ++ C E C+V+G H+ +FD F F
Sbjct: 357 --YPPGTSLSRDCNTCICRNSQWICSNE--------ECPGECLVTGQSHFKSFDNRYFTF 406
Query: 1119 QTSCPLILCTTGSRPSSD-SFPKFVVTAK-NEDRDPSLALWVKQVDVTVFG-YSIVIHRA 1175
C +L +R D SF + T + +DRD A+ + V V + G ++ ++
Sbjct: 407 SGICQYLL----ARDCQDHSFSIVIETVQCADDRD---AVCTRSVTVRLPGLHNSLVKLK 459
Query: 1176 YKHTVLVNSERLYLPLKLGQGKINIFSFGFHVV---VETDFGLKVVYDW--KTFLSITVP 1230
+ V ++ + + LPL G +I H V V +G + DW + L + +
Sbjct: 460 HGAGVAMDGQDVQLPLLKGDLRIQ------HTVTASVRLSYGEDLQMDWDGRGRLLVKLS 513
Query: 1231 RSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQ---VGCGDRCPS 1287
T GLCG YNGN DD P GL V +FG +W K CQ D C
Sbjct: 514 PVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAW-KLHGDCQDLQKQHSDPCAL 572
Query: 1288 CAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQN 1347
++ FS ++ C+++ + F CH V+P + +NC +D C + C L +
Sbjct: 573 NPRMTRFS--EEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALAS 628
Query: 1348 YASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSD-CSHYCVEGC 1406
YA+ C +G+ V WR C + CP Y C + C C ++ + C+ C+EGC
Sbjct: 629 YAAACAGRGVRVA-WREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGC 687
Query: 1407 HCDAGYVLNGKS-CILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRC 1451
C G ++ + C+ C CY DG+ ++P+ +F SD C C
Sbjct: 688 FCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIF--SDHHTMCYC 731
Score = 221 bits (564), Expect = 5e-57
Identities = 187/719 (26%), Positives = 299/719 (41%), Gaps = 86/719 (11%)
Query: 1098 ASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALW 1157
A C + G TFDG + F C +L + S F + SL+++
Sbjct: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDF-----QNGKRVSLSVY 87
Query: 1158 VKQV-DVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLK 1216
+ + D+ +F V + ++ S+ LYL + G K++ ++GF ++ +
Sbjct: 88 LGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGNFQ 147
Query: 1217 VVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWV--KRD 1274
V+ + F N T GLCG +N +DD G L S +F SW +
Sbjct: 148 VLLSDRYF----------NKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197
Query: 1275 TFCQVGCGDRCPSCAKVEGFSK--VQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSC 1332
+C+ SC G + + + C L+ + + F++CH V+P F C C
Sbjct: 198 QWCE-RASPPSSSCNISSGEMQKGLWEQCQLLKS-TSVFARCHPLVDPEPFVALCEKTLC 255
Query: 1333 IDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAI 1392
G ++ AC L YA TC +G+ + GW ++++C+ CP Y CVS C C ++
Sbjct: 256 ECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSL 315
Query: 1393 RLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCR-C 1451
+ C CV+GC C G +L+ C+ C C GK Y P + +R C C
Sbjct: 316 HINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPP-----GTSLSRDCNTC 370
Query: 1452 FRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAF 1511
RN + S+EEC CL G F++FD + F C +
Sbjct: 371 ICRN-----SQWICSNEEC-------------PGECLVTGQSHFKSFDNRYFTFSGICQY 412
Query: 1512 VLSTICQKLPDISFQLII-------NFDKWSAPNLTIISPVYFYINEEQILINDRNTVKV 1564
+L+ CQ D SF ++I + D ++T+ P ++ + + V +
Sbjct: 413 LLARDCQ---DHSFSIVIETVQCADDRDAVCTRSVTVRLP---GLHNSLVKLKHGAGVAM 466
Query: 1565 NGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGN 1624
+G V +P + G ++ + + D+Q+ ++G + + +S K CGLCGN
Sbjct: 467 DGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGN 526
Query: 1625 FNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQK 1684
+NG+ DD++T G +WK +G C +LQ Q++ C
Sbjct: 527 YNGNQGDDFLTPSGLAEPRVEDFGNAWKLHG--------DCQDLQ-KQHSDPCALNPRMT 577
Query: 1685 MQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGC-YSHKKFQLCGSLAAYGEACRS 1743
+ C LT F+ C+ + PLP+ +C D C S + LCG+LA+Y AC
Sbjct: 578 RFSEEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAG 635
Query: 1744 FGILSTEWIEKENC-----SGVVEDPCVGADCPNRTC-------ELGNGRELCGCIEPP 1790
G+ W E C G V C G C N TC E N L GC PP
Sbjct: 636 RGV-RVAWREPGRCELNCPKGQVYLQC-GTPC-NLTCRSLSYPDEECNEACLEGCFCPP 691
Score = 137 bits (345), Expect = 1e-31
Identities = 127/509 (24%), Positives = 204/509 (40%), Gaps = 69/509 (13%)
Query: 982 LECPENSHFEECITCTETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFE 1041
L CP ++ E + CT+TC+ L + + C GC C G ++CV C C +
Sbjct: 774 LVCPADNLRAEGLECTKTCQNYDLECMSM-GCVSGCLCPPGMVRHENRCVALERCPCFHQ 832
Query: 1042 GHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCI 1101
G + A ET ++ C T C+D ++ + + C DA+C
Sbjct: 833 GKEYAPGETV-----------------KIGCNTCVCRDRKWNCTD---HVC----DATCS 868
Query: 1102 VSGYGHYLTFDGFPFDFQTSCPLILCT--TGSRPSSDSFPKFVVTAKNEDRDPSLALWVK 1159
G HYLTFDG + F C +L GS P + F + N+ K
Sbjct: 869 TIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGT-----FRILVGNKGCSHPSVKCKK 923
Query: 1160 QVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVY 1219
+V + V G I + VN +R P+K + + G ++++ L VV+
Sbjct: 924 RVTILVEGGEIELFDGE-----VNVKR---PMK-DETHFEVVESGRYIILLLGKALSVVW 974
Query: 1220 DWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFC-- 1277
D +S+ + ++ Q GLCG ++G ++DL + +FG SW K + C
Sbjct: 975 DRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSW-KVSSQCAD 1033
Query: 1278 --QVGCGDRCPSC-AKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFD--SC 1332
+V +C + + V C ++ + F C+ V+P + C++D SC
Sbjct: 1034 TRKVPLDSSPATCHNNIMKQTMVDSSCRILTSD--VFQDCNKLVDPEPYLDVCIYDTCSC 1091
Query: 1333 IDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNS----------HYESCV 1382
G C + YA C G VT WR T C +C + Y SC
Sbjct: 1092 ESIGDCACFCDTIAAYAHVCAQHGKVVT-WRTATLCPQSCEERNLRENGYECEWRYNSCA 1150
Query: 1383 SVCQPRCAAIRLKSDCSHYCVEGC--HCDAGYVLNG--KSCILPHSCG-CYSDG-KYYEP 1436
CQ C + C CVEGC HC G +L+ ++C+ P C C G ++
Sbjct: 1151 PACQVTCQHPEPLA-CPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASG 1209
Query: 1437 KQLFWNSDCTRRCRCFRRNVIQCDPRQCK 1465
K++ N C+ +V+ C+
Sbjct: 1210 KKVTLNPSDPEHCQICHCDVVNLTCEACQ 1238
Score = 116 bits (291), Expect = 2e-25
Identities = 117/432 (27%), Positives = 165/432 (38%), Gaps = 50/432 (11%)
Query: 298 SCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSS 357
S SP +V E G + C V C H TFDG F GSC+Y+L + Q
Sbjct: 1930 SQSPVKVEETCGCRWTCPCV----CTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLE 1985
Query: 358 LPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGT 417
+ + R+G S +EV + + S V VN + S+P
Sbjct: 1986 VILHNGACSPGARQGCMKS------IEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNME 2039
Query: 418 VKIYQSGISTAVETDFGLLVTFDGQH--YASISVPGSYINSTCGLCGNYNKNPLDDFLRP 475
V +Y + + G + TF Q+ + P ++ + T GLCG ++N +DF+
Sbjct: 2040 VNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLR 2099
Query: 476 DGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLW 535
DG L + W V C + C D S +C L PL+
Sbjct: 2100 DGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPD---------SSHCQVLLL---PLF 2147
Query: 536 -ECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVST 594
EC V+ P F C D C +C+ I +YA +C+ G+ + DWRT C
Sbjct: 2148 AECHKVLAPATFYAICQQDSCHQEQ----VCEVIASYAHLCRTNGVCV-DWRTPDFC--A 2200
Query: 595 VQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKC---- 650
+ CP Y+ C CP C +S C +EGC C V+ CVP C
Sbjct: 2201 MSCPPSLVYNHCEHGCPRHCDGNVSS--CGDHPSEGCFCPPDKVMLEGSCVPEEACTQCI 2258
Query: 651 GCDFDGHYYTMGEFFWATANCTVQ-CLCEEGGDVYCFNK--------TCGSGEVCAVEDG 701
G D H + W + Q C C G V C + TCG EV +
Sbjct: 2259 GEDGVQHQFLEA---WVPDHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQN 2315
Query: 702 YQGCFPKRETVC 713
C P+ E VC
Sbjct: 2316 ADQCCPEYECVC 2327
Score = 100 bits (250), Expect = 1e-20
Identities = 127/513 (24%), Positives = 195/513 (38%), Gaps = 90/513 (17%)
Query: 610 CPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATA 669
C TC + + C GC C G V ++CV L +C C G Y GE
Sbjct: 788 CTKTCQNYDLEC-MSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGC 846
Query: 670 NCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASY 729
N C+C + K + VC + C TFDG Y
Sbjct: 847 NT---CVCRD-------RKWNCTDHVC-------------DATCSTIGMAHYLTFDGLKY 883
Query: 730 AFPSEFSYTLLKT-CPERPEYLEIDI-NKKKPDAGPAWLRGLRILVADQEVKI--GGIGA 785
FP E Y L++ C P I + NK + + ILV E+++ G +
Sbjct: 884 LFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNV 943
Query: 786 SEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCT 845
+ E+ SG+ I ++ VV ++ I ++ L TY
Sbjct: 944 KRPMKDETHFEVV---ESGRYIIL-----LLGKALSVVWDRHLSISVV---LKQTYQEKV 992
Query: 846 GGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKA--------CN 897
GLCG ++ +++ N + ++ F SW + +C D K C+
Sbjct: 993 CGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV-----SSQCADTRKVPLDSSPATCH 1047
Query: 898 NDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLC--QSGGNESELCD 955
N+ ++K S C I+ ++ F +C+ +V+ Y C++ C +S G+ + CD
Sbjct: 1048 NN--IMKQTMVDSSCRIL---TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCD 1102
Query: 956 SVARYASACKNADVEVGPWRTYDFCPLECPENSHFE---EC----ITCTETCETLTLGP- 1007
++A YA C +V WRT CP C E + E EC +C C+ P
Sbjct: 1103 TIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPE 1161
Query: 1008 --ICVDSCSEGC--QCDEGYAL--LGSQCVTRSECG-CNFEGHQLATNETFWVDLD---- 1056
C C EGC C G L L CV +C C G + A+ + ++
Sbjct: 1162 PLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEH 1221
Query: 1057 CQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGL 1089
CQI C+C + + C E C E GGL
Sbjct: 1222 CQI-CHCDVVN-------LTC---EACQEPGGL 1243
Score = 100 bits (249), Expect = 2e-20
Identities = 95/404 (23%), Positives = 149/404 (36%), Gaps = 60/404 (14%)
Query: 1370 VTCPPNSHYESCVSVCQPR-----CAAIRLKSD-------CSHY--------CVEGCHCD 1409
V P SH C+P C A L+++ C +Y CV GC C
Sbjct: 752 VLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCP 811
Query: 1410 AGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEE 1469
G V + C+ C C+ GK Y P + T + C N C R+ +
Sbjct: 812 PGMVRHENRCVALERCPCFHQGKEYAPGE-------TVKIGC---NTCVCRDRKWNCTDH 861
Query: 1470 CALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVL-STICQKLPDISFQLI 1528
C +T C G + TFDG FP C +VL C P +F+++
Sbjct: 862 V--------CDAT----CSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG-TFRIL 908
Query: 1529 INFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFL 1588
+ S P++ V + +I + D V P ++ S ++
Sbjct: 909 VGNKGCSHPSVKCKKRVTILVEGGEIELFDGEV------NVKRPMKDETHFEVVESGRYI 962
Query: 1589 VIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLA 1648
++ + + ++ I + + + Q KVCGLCGNF+G +D + + V
Sbjct: 963 ILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFG 1022
Query: 1649 QSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLL 1708
SWK + ++ A C N +++ D C LT FQ C L+
Sbjct: 1023 NSWKVSSQ-----CADTRKVPLDSSPATCHNNIMKQTMVDSSCRILT--SDVFQDCNKLV 1075
Query: 1709 DPLPFYESCYLDGCYSHKKFQ---LCGSLAAYGEACRSFGILST 1749
DP P+ + C D C C ++AAY C G + T
Sbjct: 1076 DPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVT 1119
Score = 100 bits (248), Expect = 2e-20
Identities = 95/383 (24%), Positives = 145/383 (37%), Gaps = 36/383 (9%)
Query: 1092 CQARTDASCIVSGYG--HYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNED 1149
C R C+ +G H +TFDG F SC +L + V N
Sbjct: 1940 CGCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLE-------VILHNGA 1992
Query: 1150 RDPSLALW-VKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVV 1208
P +K ++V S+ +H + V VN + +P G ++N++ H V
Sbjct: 1993 CSPGARQGCMKSIEVKHSALSVELHSDME--VTVNGRLVSVPYVGGNMEVNVYGAIMHEV 2050
Query: 1209 VETDFGLKVVYDWKT--FLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEF 1266
G + + F P++ + TYGLCG + N +D + G + +
Sbjct: 2051 RFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTL 2110
Query: 1267 GQSWV--KRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFY 1324
Q W + CQ ++C V S Q L L+P F++CH + P FY
Sbjct: 2111 VQEWTVQRPGQTCQPILEEQC----LVPDSSHCQVL--LLP----LFAECHKVLAPATFY 2160
Query: 1325 KNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSV 1384
C DSC + C + +YA C+T G+ V WR C ++CPP+ Y C
Sbjct: 2161 AICQQDSCHQ----EQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPPSLVYNHCEHG 2215
Query: 1385 CQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSC-GCYSDGKYYEPKQLFWNS 1443
C C S C + EGC C V+ SC+ +C C + W
Sbjct: 2216 CPRHCDG--NVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVP 2273
Query: 1444 D--CTRRCRCFRRNVIQCDPRQC 1464
D + C C + C + C
Sbjct: 2274 DHQPCQICTCLSGRKVNCTTQPC 2296
Score = 100 bits (248), Expect = 2e-20
Identities = 98/391 (25%), Positives = 158/391 (40%), Gaps = 52/391 (13%)
Query: 704 GCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKK--KPDA 761
GC VC S + + TFDG ++ SY L + + + LE+ ++ P A
Sbjct: 1941 GCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN---KEQDLEVILHNGACSPGA 1997
Query: 762 GPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRN-KNSTTVESK 820
++ + + + V++ EV +NG+ V +P+ + ++ +Y +
Sbjct: 1998 RQGCMKSIEVKHSALSVELHS--DMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHL 2055
Query: 821 GVVTVQYSDIGLLYIRLST-TYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWT 879
G + ++LS T+ + T GLCG + N +++F L +G T + ++ WT
Sbjct: 2056 GHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWT 2115
Query: 880 ------TFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVT 933
T + I +C S C ++ P F ECH V+
Sbjct: 2116 VQRPGQTCQPILEEQC---------------LVPDSSHCQVLLLP---LFAECHKVLAPA 2157
Query: 934 AYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC 993
+Y C Q ++ ++C+ +A YA C+ V V WRT DFC + CP + + C
Sbjct: 2158 TFYAICQ----QDSCHQEQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHC 2212
Query: 994 -ITCTETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSEC----GCNFEGHQLATN 1048
C C+ C D SEGC C +L CV C G + HQ
Sbjct: 2213 EHGCPRHCDGNVSS--CGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFL-- 2268
Query: 1049 ETFWV--DLDCQIFCYCSGTDNRVHCETIPC 1077
WV CQI SG +V+C T PC
Sbjct: 2269 -EAWVPDHQPCQICTCLSG--RKVNCTTQPC 2296
Score = 99.0 bits (245), Expect = 4e-20
Identities = 101/406 (24%), Positives = 152/406 (37%), Gaps = 45/406 (11%)
Query: 282 KCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSA-VETSTCVVFGEPHYHTFDGFLFHF 340
+C C E E C + + + C+ V +TC G HY TFDG + F
Sbjct: 826 RCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLF 885
Query: 341 QGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRV 400
G C Y+L Q S+ F + N+ +V K +++ V G +I + G
Sbjct: 886 PGECQYVLV-QDYCGSNPGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDG----- 939
Query: 401 KVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGL 460
++ P+ D ++ +SG + L V +D S+ + +Y CGL
Sbjct: 940 ---EVNVKRPMK-DETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGL 995
Query: 461 CGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVD--------NCTQCDA 512
CGN++ +D + + +D G SW+V S C D + C
Sbjct: 996 CGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV-------SSQCADTRKVPLDSSPATCHN 1048
Query: 513 ATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNG--TLLCQAIQA 570
C L T +C +VDP ++ C+YD CS G C I A
Sbjct: 1049 NIMKQTMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAA 1106
Query: 571 YALVCQALGIPIGDWRTQTGCVSTVQCPSFS--------HYSVCTSSCPDTCSDLTASRN 622
YA VC G + WRT T C + + + Y+ C +C TC
Sbjct: 1107 YAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQH-PEPLA 1164
Query: 623 CATPCTEGC--ECNQGFVLS--TSQCVPLHKCG-CDFDGHYYTMGE 663
C C EGC C G +L CV C C+ G + G+
Sbjct: 1165 CPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGK 1210
Score = 88.2 bits (217), Expect = 8e-17
Identities = 86/332 (25%), Positives = 135/332 (40%), Gaps = 57/332 (17%)
Query: 1475 GVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKW 1534
G RG + T+ C G TFDG+ F C+++L+ CQK SF +I +F
Sbjct: 25 GTRG--RSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR---SFSIIGDFQNG 79
Query: 1535 SAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSP 1594
+L++ +F I+ + +N TV +V++P Y+S+G L ++T
Sbjct: 80 KRVSLSVYLGEFFDIH---LFVN--GTVTQGDQRVSMP---------YASKG-LYLETEA 124
Query: 1595 DIQIYY-------------NGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPV 1641
YY +G ++ +S+R NK CGLCGNFN DD++T G
Sbjct: 125 G---YYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLT 181
Query: 1642 VSSVVLAQSWKTNGMQK-----RPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTD 1696
A SW + ++ P + SCN + + + LK T
Sbjct: 182 SDPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQL---------LKSTS 232
Query: 1697 MKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQ-LCGSLAAYGEACRSFGILSTEWIEKE 1755
+ F C+ L+DP PF C C + C +L Y C G++ W +
Sbjct: 233 V---FARCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHS 289
Query: 1756 NCSGVVEDPCVGADCPN---RTCELGNGRELC 1784
CS V C + RTC+ + E+C
Sbjct: 290 ACSPVCPAGMEYRQCVSPCARTCQSLHINEMC 321
Score = 54.3 bits (129), Expect = 1e-06
Identities = 69/318 (21%), Positives = 122/318 (38%), Gaps = 36/318 (11%)
Query: 1446 TRRCRCFRRNVIQCDPRQC--KSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFL 1503
+ R C R C Q K +E C GC T C + TFDG
Sbjct: 1914 SHRVNCDRGLRPSCPNSQSPVKVEETC-------GCRWTCPCVCTGSSTRHIVTFDGQNF 1966
Query: 1504 RFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVK 1563
+ +C++VL K D+ ++ N + + + + ++ V
Sbjct: 1967 KLTGSCSYVLFQ--NKEQDLEV-ILHNGACSPGARQGCMKSIEVKHSALSVELHSDMEVT 2023
Query: 1564 VNGTQVNVPFITG-LATKIYSSEGFLV-IDTSPDIQIYYNGFNVIKISISER-LQNKVCG 1620
VNG V+VP++ G + +Y + V + I + N ++ +S + +K G
Sbjct: 2024 VNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYG 2083
Query: 1621 LCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNV 1680
LCG + + +D++ G L Q W +RP +C + + + D+
Sbjct: 2084 LCGICDENGANDFMLRDGTVTTDWKTLVQEWTV----QRP-GQTCQPI-LEEQCLVPDSS 2137
Query: 1681 HIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQLCGSLAAYGEA 1740
H Q + + F C+ +L P FY C D C+ Q+C +A+Y
Sbjct: 2138 HCQVL-----------LLPLFAECHKVLAPATFYAICQQDSCHQE---QVCEVIASYAHL 2183
Query: 1741 CRSFGILSTEWIEKENCS 1758
CR+ G+ +W + C+
Sbjct: 2184 CRTNGV-CVDWRTPDFCA 2200
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 270 bits (690), Expect = 1e-71
Identities = 128/235 (54%), Positives = 167/235 (71%), Gaps = 4/235 (1%)
Query: 29 YPFW--QNDTKTPKVDDGSSSEIKLAIPVFFFGVPYRTVYVNNNGVVSFNVLVSQFTPES 86
YPF + D TPK DDG S L++P FFG + +YVNNNG++SF VSQFTP +
Sbjct: 32 YPFGAERGDAVTPKQDDGGSGLRPLSVPFPFFGAEHSGLYVNNNGIISFLKEVSQFTPVA 91
Query: 87 FPLTDGRAFVAPFWADVHNGIRGEIYYRETMEPAILKRATKDIRKYFKDMATFSATWVFI 146
FP+ R VA FWADV N G++YYRE +PA+L+RAT+D+R YF ++ F+ATWVF+
Sbjct: 92 FPIAKDRCVVAAFWADVDNRRAGDVYYREATDPAMLRRATEDVRHYFPELLDFNATWVFV 151
Query: 147 VTWEEVTFYGGSSTTPVNTFQAVLVSDGSYTFTLFNYYEINWTTGT-ASGGDPLTGLGGV 205
TW VTF+GGSS++PVNTFQ VL++DG +FT+FNY I WTTGT AS G TGLGG+
Sbjct: 152 ATWYRVTFFGGSSSSPVNTFQTVLITDGKLSFTIFNYESIVWTTGTHASSGGNATGLGGI 211
Query: 206 MAQAGFNGGNLTNFFSLPGSRTPEIVNIQETTNVNVPGRWAFKVDGKEIDPANGC 260
AQAGFN G+ +FS+PGSRT ++ ++ TTNV VPGRWAF++D ++ GC
Sbjct: 212 AAQAGFNAGDGQRYFSIPGSRTADMAEVETTTNVGVPGRWAFRIDDAQV-RVGGC 265
Score = 50.8 bits (120), Expect = 1e-05
Identities = 70/272 (25%), Positives = 92/272 (33%), Gaps = 50/272 (18%)
Query: 861 CLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSN 920
CL GKC D+ S+T C+ G + C+ D ++ G N
Sbjct: 278 CLNGGKCIDDCVTGNPSYT-----CSCLSGFTGRRCHLDVNECASQPCQNG-GTCTHGIN 331
Query: 921 SSFLEC---HGVVNVTAYYRTCLFRLCQSGG-----NESELCDSVARYASACKNADVE-- 970
S +C G C + CQ GG N S +C A Y A DV+
Sbjct: 332 SFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDC 391
Query: 971 --------------VGPWRTY---DFCPLECPENSHFEECITCTETCETLTLGPICVDSC 1013
VG + F L C H + C G CVD+
Sbjct: 392 SPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHN---GGTCVDA- 447
Query: 1014 SEG--CQCDEGYALLGSQCVTR--SECGCNFEGHQLATNETFWVDLDCQIFCY---CSGT 1066
+G C+C EG+ +G C R +C C G L N T C + + C
Sbjct: 448 DQGYVCECPEGF--MGLDCRERVPDDCECRNGGRCLGANTTL---CQCPLGFFGLLCEFE 502
Query: 1067 DNRVHCE-TIPCKDDEYCMEEGGLYYCQARTD 1097
+ C C D YCME GG Y C TD
Sbjct: 503 ITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTD 534
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 268 bits (685), Expect = 4e-71
Identities = 269/1147 (23%), Positives = 440/1147 (38%), Gaps = 189/1147 (16%)
Query: 712 VCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDA---GPAWLRG 768
VC N TFDG + FP Y C R Y E ++ K+ PA +
Sbjct: 36 VCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVHLKRGPGQAEAPAGVES 93
Query: 769 LRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYS 828
+ + + D + + A LNG V P + P L I ++ T V S+ +T+ ++
Sbjct: 94 ILLTIKDDTIYLTRHLAV---LNGAVVSTPHYSPG--LLIEKSDAYTKVYSRAGLTLMWN 148
Query: 829 DIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGE 888
L + L T + N T GLCG YN S + FL F + E
Sbjct: 149 REDALMLELDTKFRNHTCGLCGDYNGLQS-------------YSEFLSDGVLFSPL---E 192
Query: 889 CGDLLK------ACNN-DSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLF 941
G++ K C + + E+ S R + +F +C +V + Y R C
Sbjct: 193 FGNMQKINQPDVVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQ 252
Query: 942 RLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENS-HFEECITCTETC 1000
C+ G ++ +C +VA ++ C +A G WRT CP CP N + E C +TC
Sbjct: 253 DRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTC 312
Query: 1001 ETLTLGPICVDSCSEGCQCDEG--YALLG-SQCVTRSECGCNFEGHQLATNETFWVDLDC 1057
L + +C + +GC C EG Y +G S CV S+C C GH + + DC
Sbjct: 313 SHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQE--ITNDC 370
Query: 1058 QIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFD 1117
+ C C+ R C+ +PC +C + G H TFDG +
Sbjct: 371 EQ-CVCNA--GRWVCKDLPCP-------------------GTCALEGGSHITTFDGKTYT 408
Query: 1118 FQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYK 1177
F C +L G S + + + D+ L V D ++V+ ++
Sbjct: 409 FHGDCYYVLAK-GDHNDSYALLGELAPCGSTDKQTCLKTVVLLADKKK---NVVVFKS-D 463
Query: 1178 HTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLS--ITVPRSMQN 1235
+VL+N ++ LP + S +H++V G+++ + +T+ ++ Q
Sbjct: 464 GSVLLNELQVNLPHVTASFSVFRPS-SYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQG 522
Query: 1236 STYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGCGDRC-----PSCAK 1290
GLCG +NG DD + GL+ ++ F +W Q C D+ P
Sbjct: 523 QVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWK-----AQSSCHDKLDWLDDPCSLN 577
Query: 1291 VEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYAS 1350
+E + + CSL+ F +CHS V+P +YK C +D+C C+ L +YA
Sbjct: 578 IESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYAR 637
Query: 1351 TCQTQGITVTGWR-------------------NYTSCTVTCPPNSHYES-CVSVCQP--- 1387
C +G+ + GWR N T+C TC S +S C+ P
Sbjct: 638 ACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDG 697
Query: 1388 -------------RCAAIRLKSDCSHYCV------------EGCHCDAGYV------LNG 1416
RC + K C H + E C C G + L G
Sbjct: 698 CGCPDHTFLDEKGRCVPLA-KCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIG 756
Query: 1417 KSCILPH---SCGCYSDGKYYEPKQL--------FWNSDCT------------------- 1446
+SC P C + +P+ L +++++C
Sbjct: 757 QSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVV 816
Query: 1447 -RRCRCFRRNVIQCDPRQCKSD-EECALRNGVRGCFSTKT-SYCLAAGGGVFRTFDGAFL 1503
+ C C N + + K D C + G C C G G + TFDG +
Sbjct: 817 EKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYY 876
Query: 1504 RFPANCAFV-LSTICQKLPDI-SFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNT 1561
F +C++V + C + + SF +I +T + ++ ++ + D++
Sbjct: 877 DFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHR 936
Query: 1562 VKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGL 1621
V + + + T Y LV+++S I + ++ + I ++ + VCGL
Sbjct: 937 VVIQRDEGHHVAYTTREVGQY-----LVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGL 991
Query: 1622 CGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVH 1681
CGNF+ +D+ T V S + SWK AP+C ++ S C
Sbjct: 992 CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE--------APTCPDV--STNPEPCSLNP 1041
Query: 1682 IQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQ---LCGSLAAYG 1738
++ + C L F C+ +DP PFYE+C D C C ++A+Y
Sbjct: 1042 HRRSWAEKQCSIL--KSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYA 1099
Query: 1739 EACRSFG 1745
+ C G
Sbjct: 1100 QECTKEG 1106
Score = 211 bits (538), Expect = 5e-54
Identities = 198/779 (25%), Positives = 315/779 (40%), Gaps = 84/779 (10%)
Query: 320 STCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVK 379
+ C +G HY TFDG +F F G C Y A C S F+V K + A + V+
Sbjct: 35 NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVHLKRGPGQAEAPAGVE 92
Query: 380 ELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTF 439
+ + + I + + +N V S P + I +S T V + GL + +
Sbjct: 93 SILLTIKDDTIYLTR---HLAVLNGAVVSTPHYSP--GLLIEKSDAYTKVYSRAGLTLMW 147
Query: 440 DGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKC 499
+ + + + + N TCGLCG+YN DG S L+ G ++ D C
Sbjct: 148 NREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDG-VLFSPLEFGNMQKINQPDVVC 206
Query: 500 D--------SGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCV 551
+ + C ++ +C+ A F +C +V ++ +C
Sbjct: 207 EDPEEEVAPASCSEHRAECERLLTAEAFA---------------DCQDLVPLEPYLRACQ 251
Query: 552 YDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCP 611
D C T +C + ++ C G G+WRT T C T CP Y S C
Sbjct: 252 QDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKT--CPGNLVYLESGSPCM 309
Query: 612 DTCSDLTASRNCATPCTEGCECNQGFV---LSTSQCVPLHKCGCDFDGHYYTMGEFFWAT 668
DTCS L S C +GC C +G V + S CVP+ +C C GH YT G+
Sbjct: 310 DTCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQ---EI 366
Query: 669 ANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGAS 728
N QC+C G V C + C CA+E G + TFDG +
Sbjct: 367 TNDCEQCVCNAGRWV-CKDLPCPG--TCALEGGSH-----------------ITTFDGKT 406
Query: 729 YAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGA-SE 787
Y F + Y L K L ++ L+ + +L+AD++ + +
Sbjct: 407 YTFHGDCYYVLAKGDHNDSYALLGELAPCGSTDKQTCLKTV-VLLADKKKNVVVFKSDGS 465
Query: 788 VKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGV---VTVQYSDIGLLYIRLSTTYFNC 844
V LN +V LP H + ++R + + S + + VQ + + L++ L
Sbjct: 466 VLLNELQVNLP--HVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQ 523
Query: 845 TGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLK 904
GLCG +N D+F +G A F +W + C+ + L C+ + E
Sbjct: 524 VQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKA-QSSCHDKLDWLDDPCSLNIESAN 582
Query: 905 FYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASAC 964
+ + C ++ + + F CH V+ YY+ C + C NE LC +++ YA AC
Sbjct: 583 Y--AEHWCSLLK-KTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARAC 639
Query: 965 KNADVEVGPWRTYDFCPLE---CPENSHF-EECITCTETCETLT-LGPICVDSCS--EGC 1017
V + WR + C + CP + F TC +TC +L+ C++ + +GC
Sbjct: 640 TAKGVMLWGWREH-VCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGC 698
Query: 1018 QC-DEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETI 1075
C D + +CV ++C C G L + V + + C C D R+HC I
Sbjct: 699 GCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGD---VVVRQEERCVC--RDGRLHCRQI 752
Score = 177 bits (449), Expect = 1e-43
Identities = 205/894 (22%), Positives = 323/894 (36%), Gaps = 159/894 (17%)
Query: 321 TCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKE 380
TC + G H TFDG + F G C Y+LA+ S + + + + V
Sbjct: 390 TCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLGELAPCGSTDKQTCLKTVVL 449
Query: 381 LSVEVNGYKILIPKGSYGRVKVNDLVTSLP-VTLDLGTVKIYQSGISTAVETDFGLLVTF 439
L+ + K ++ S G V +N+L +LP VT + I ++ L V
Sbjct: 450 LA---DKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQL 506
Query: 440 DGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKC 499
+++ + GLCGN+N DDF G + +W K
Sbjct: 507 APVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTW-------KA 559
Query: 500 DSGCVDNCT----QCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLC 555
S C D C E+ + +C L KT+ P C + VDP + C YD C
Sbjct: 560 QSSCHDKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTC 619
Query: 556 SVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCS 615
+ ++N LC A+ +YA C A G+ + WR CP+ + ++C TC
Sbjct: 620 NCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCR 679
Query: 616 DLT-ASRNCATPCT--EGCEC-NQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANC 671
L+ A +C +GC C + F+ +CVPL KC C G Y G+
Sbjct: 680 SLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGD---VVVRQ 736
Query: 672 TVQCLCEEGG------------------DVYCFNKT-----------------------C 690
+C+C +G + C N T C
Sbjct: 737 EERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTEC 796
Query: 691 GSGEVCA---VEDGYQGCFPKRETVCLLSQN--------------------------QVL 721
SG VC ++DG GC ++E C+ + + V
Sbjct: 797 VSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVC 856
Query: 722 H------------TFDGASYAFPSEFSYTLLKT-CPERPEYLEIDINKKKPDAGPAWLRG 768
H TFDG Y F SY ++ C + I + G +
Sbjct: 857 HGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGV-- 914
Query: 769 LRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNS---TTVESKGVVTV 825
+ +KI +G +E+KL + + G Y + VES + V
Sbjct: 915 ----TCSKAIKIF-MGRTELKLEDKH-RVVIQRDEGHHVAYTTREVGQYLVVESSTGIIV 968
Query: 826 QYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEIC 885
+ ++I+L+ +Y GLCG ++ ++++F + + F SW
Sbjct: 969 IWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAP--- 1025
Query: 886 NGECGDLLKACNNDSELLKFYR---SRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFR 942
C D+ + N + L +R + +C I+ +S F CH V+ +Y C+
Sbjct: 1026 --TCPDV--STNPEPCSLNPHRRSWAEKQCSIL---KSSVFSICHSKVDPKPFYEACVHD 1078
Query: 943 --LCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENS-------HFEEC 993
C +GG+ C +VA YA C V WRT D CP+ C + H+E C
Sbjct: 1079 SCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCPIFCDYYNPPHECEWHYEPC 1137
Query: 994 ITCT-ETCETL-----TLGPICVDSCSEGCQCDEG-YALLGSQCVTRSECGCNFEGHQLA 1046
+ ETC T+ + ++ C C D Y +CVT +CGC E
Sbjct: 1138 GNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYP 1197
Query: 1047 TNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASC 1100
+ + C+ C C+ + V C E G Q + A C
Sbjct: 1198 PGASVPTEETCK-SCVCTNSSQVV------------CRPEEGKILNQTQDGAFC 1238
Score = 163 bits (412), Expect = 2e-39
Identities = 163/630 (25%), Positives = 249/630 (39%), Gaps = 90/630 (14%)
Query: 865 GKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFL 924
G C N VFL + TT C C L +A DS L+ + CG +
Sbjct: 659 GSCP-NSQVFLYNLTT----CQQTCRSLSEA---DSHCLEGFAPVDGCGCPDHTFLDEKG 710
Query: 925 ECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVE--------VGPWRT 976
C + + Y+R G E D V R C D +G T
Sbjct: 711 RCVPLAKCSCYHR----------GLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCT 760
Query: 977 YDFCPLECPENSHFEECITCTETCETLTLGPICVDSCSEGCQCDEGYALLG-SQCVTRSE 1035
++C + +C+TL G + C GC C +G G CV E
Sbjct: 761 APKIHMDCSNLTALATSKPRALSCQTLAAGYYHTE-CVSGCVCPDGLMDDGRGGCVVEKE 819
Query: 1036 CGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYC-QA 1094
C C DL Y SG +V C T CK G + C QA
Sbjct: 820 CPCVHNN-----------DL------YSSGAKIKVDCNTCTCKR--------GRWVCTQA 854
Query: 1095 RTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSL 1154
+C + G GHY+TFDG +DF C + +S S F + +N +
Sbjct: 855 VCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNS-SLGSFSIITENVPCGTTG 913
Query: 1155 ALWVKQVDVTVFGYSIVIHRAYKHTVLVNSER----LYLPLKLGQGKINIFSFGFHVVVE 1210
K + + + + + KH V++ + Y ++GQ ++VVE
Sbjct: 914 VTCSKAIKIFMGRTELKLED--KHRVVIQRDEGHHVAYTTREVGQ----------YLVVE 961
Query: 1211 TDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSW 1270
+ G+ V++D +T + I + S + + GLCG ++ ++D ++ SS +FG SW
Sbjct: 962 SSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSW 1021
Query: 1271 VKRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFD 1330
+ T V P S ++ CS++ +++ FS CHSKV+P FY+ C+ D
Sbjct: 1022 KEAPTCPDVSTNPE-PCSLNPHRRSWAEKQCSIL--KSSVFSICHSKVDPKPFYEACVHD 1078
Query: 1331 SCI--DGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTC----PPNS---HYESC 1381
SC GG + CS + +YA C +G V WR C + C PP+ HYE C
Sbjct: 1079 SCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCPIFCDYYNPPHECEWHYEPC 1137
Query: 1382 VSVCQPRCAAIR-LKSDCSHYCVEGCH--CDAG---YVLNGKSCILPHSCGCYSDGKYYE 1435
+ C I + S+ S +EGC+ C Y + K C+ CGCY + +Y
Sbjct: 1138 GNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYP 1197
Query: 1436 PKQLFWNSDCTRRCRCFRRNVIQCDPRQCK 1465
P + + C C + + C P + K
Sbjct: 1198 PGASVPTEETCKSCVCTNSSQVVCRPEEGK 1227
Score = 159 bits (403), Expect = 2e-38
Identities = 185/768 (24%), Positives = 299/768 (38%), Gaps = 99/768 (12%)
Query: 1100 CIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVK 1159
C G HY TFDG F F C + S+ +F V K V+
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASD----CRGSYKEFAVHLKRGPGQAEAPAGVE 92
Query: 1160 QVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVY 1219
+ +T+ +I + R H ++N + P G + I + V + GL +++
Sbjct: 93 SILLTIKDDTIYLTR---HLAVLNGAVVSTP-HYSPGLL-IEKSDAYTKVYSRAGLTLMW 147
Query: 1220 DWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFG--QSWVKRDTFC 1277
+ + L + + +N T GLCG YNG + G+L S + EFG Q + D C
Sbjct: 148 NREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNMQKINQPDVVC 206
Query: 1278 QVGCGDRCP-SCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGG 1336
+ + P SC+ E ++ ++L + AF+ C V + + C D C G
Sbjct: 207 EDPEEEVAPASCS--EHRAECERLLTA-----EAFADCQDLVPLEPYLRACQQDRCRCPG 259
Query: 1337 AVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKS 1396
CS + ++ C G WR T C TCP N Y S C C+ + + S
Sbjct: 260 GDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLEVSS 319
Query: 1397 DCSHYCVEGCHCDAGYV---LNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFR 1453
C + ++GC C G V + C+ C C G Y P Q N DC +C C
Sbjct: 320 LCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEITN-DC-EQCVCNA 377
Query: 1454 RNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVL 1513
+ CK D C C GG TFDG F +C +VL
Sbjct: 378 GRWV------CK-DLPCP-------------GTCALEGGSHITTFDGKTYTFHGDCYYVL 417
Query: 1514 STICQKLPDISFQLIINFDKW-SAPNLTIISPVYFYINEEQ--ILINDRNTVKVNGTQVN 1570
+ + + S+ L+ S T + V ++++ ++ +V +N QVN
Sbjct: 418 A---KGDHNDSYALLGELAPCGSTDKQTCLKTVVLLADKKKNVVVFKSDGSVLLNELQVN 474
Query: 1571 VPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIK--ISISERLQNKVCGLCGNFNGD 1628
+P +T + S +++ + +++ V++ +++ + Q +V GLCGNFNG
Sbjct: 475 LPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGL 534
Query: 1629 LTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPL----APSCNELQFSQYAAMCDNVHIQK 1684
DD+ T G + A +WK L P ++ + YA
Sbjct: 535 EGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYA---------- 584
Query: 1685 MQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGC-YSHKKFQLCGSLAAYGEACRS 1743
+ +C L + F C+ +DP +Y+ C D C + + LC +L++Y AC +
Sbjct: 585 ---EHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTA 641
Query: 1744 FGILSTEWIEKENCSGVVEDPCVGADCPN------------RTC-ELGNGRELC--GCIE 1788
G++ W E V + VG+ CPN +TC L C G
Sbjct: 642 KGVMLWGWREH------VCNKDVGS-CPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAP 694
Query: 1789 PPPYGNNSHDIIDAEVTCKAAQMEVSISKCKLFQLGFEREGVRINDRQ 1836
G H +D + C V ++KC + G E + RQ
Sbjct: 695 VDGCGCPDHTFLDEKGRC------VPLAKCSCYHRGLYLEAGDVVVRQ 736
Score = 130 bits (327), Expect = 1e-29
Identities = 128/494 (25%), Positives = 197/494 (39%), Gaps = 54/494 (10%)
Query: 282 KCRCLDFNNEIYCQEASCS-PYEVCEPK-GKFFYCSAVETSTCVVFGEPHYHTFDGFLFH 339
+C C+ NN++Y A C K G++ AV TC ++G HY TFDG +
Sbjct: 819 ECPCVH-NNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYD 877
Query: 340 FQGSCAYLLARQ-CLQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYG 398
F G C+Y+ + C Q SSL FS+ +N + V+ K + + + ++ +
Sbjct: 878 FDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRV 937
Query: 399 RVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTC 458
++ ++ T ++G + VE+ G++V +D + I + SY + C
Sbjct: 938 VIQRDEGHHVAYTTREVGQYLV--------VESSTGIIVIWDKRTTVFIKLAPSYKGTVC 989
Query: 459 GLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVD---NCTQCDAATE 515
GLCGN++ +DF D S LD G S WK C D N C
Sbjct: 990 GLCGNFDHRSNNDFTTRDHMVVSSELDFGNS-------WKEAPTCPDVSTNPEPCSLNPH 1042
Query: 516 ALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNG--TLLCQAIQAYAL 573
+ C L + + C + VDP F +CV+D CS G C A+ +YA
Sbjct: 1043 RRSWAEKQCSILKSSVFSI--CHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQ 1100
Query: 574 VCQALGIPIGDWRTQTGCVSTVQCPSFS-------HYSVCTSSCPDTCSDLTA-SRNCAT 625
C G + WRT C + C ++ HY C + +TC + N +
Sbjct: 1101 ECTKEGACV-FWRTPDLC--PIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISV 1157
Query: 626 PCTEGC--ECNQG---FVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEG 680
EGC C + + +CV KCGC + +Y G C C+C
Sbjct: 1158 SYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCK-SCVCTNS 1216
Query: 681 GDVYC-------FNKTCGSGEVCAVE-DGYQGCFPKRETVC-LLSQNQVLHTFDGASY-A 730
V C N+T G C E G G K +C + ++ L TF +
Sbjct: 1217 SQVVCRPEEGKILNQT-QDGAFCYWEICGPNGTVEKHFNICSITTRPSTLTTFTTITLPT 1275
Query: 731 FPSEFSYTLLKTCP 744
P+ F+ T T P
Sbjct: 1276 TPTTFTTTTTTTTP 1289
Score = 130 bits (326), Expect = 2e-29
Identities = 119/451 (26%), Positives = 190/451 (42%), Gaps = 52/451 (11%)
Query: 1048 NETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYY--------CQARTDAS 1099
NET+W+ C F +N V + C+ GL C +
Sbjct: 4422 NETWWL---CDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECD 4478
Query: 1100 CIVSGYG--HYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDP----- 1152
C +G+G HY+TFDG + +Q +C +L S PS D+F ++ + D
Sbjct: 4479 CYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS-PSVDNFGVYIDNYHCDPNDKVSCPR 4537
Query: 1153 SLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVET- 1211
+L + + +V + V + V VN + + LP K + + ++ G + VV+
Sbjct: 4538 TLIVRHETQEVLI---KTVHMMPMQVQVQVNRQAVALPYK--KYGLEVYQSGINYVVDIP 4592
Query: 1212 DFGLKVVYDWKTFLSITVP-RSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSW 1270
+ G+ V Y+ +F S+ +P N+T G CG DD +P G + S+ W
Sbjct: 4593 ELGVLVSYNGLSF-SVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 4651
Query: 1271 VKRDT---FCQVGCGDRCPSCAKVEGFSKV--------QQLCSLIPNQNAAFSKCHSKVN 1319
+ D C V G K LC LI +++ F++CH+ V
Sbjct: 4652 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLI--KDSLFAQCHALVP 4709
Query: 1320 PTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYT--SCTVTCPPNSH 1377
P +Y C+FDSC G+ C+ LQ YA+ C Q I + WRN+T +C V CP +
Sbjct: 4710 PQHYYDACVFDSCFMPGS-SLECASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHRE 4767
Query: 1378 YESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAG---YVLNGKSCILPHSCGCYSDGKYY 1434
Y++C +P C + + + + VEGC C G Y C+ +CGC
Sbjct: 4768 YQACGPAEEPTCKSSSSQQN-NTVLVEGCFCPEGTMNYAPGFDVCV--KTCGCVGPDNVP 4824
Query: 1435 EPKQLFWNSDCTRRCRCFR-RNVIQCDPRQC 1464
+ DC + C C + I C P++C
Sbjct: 4825 REFGEHFEFDC-KNCVCLEGGSGIICQPKRC 4854
Score = 125 bits (315), Expect = 3e-28
Identities = 113/398 (28%), Positives = 172/398 (43%), Gaps = 30/398 (7%)
Query: 322 CVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEH-RRGSAVSWVKE 380
C +G+PHY TFDG + +QG+C Y+L + + S+ F V N H VS +
Sbjct: 4481 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEI--SPSVDNFGVYIDNYHCDPNDKVSCPRT 4538
Query: 381 LSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGT--VKIYQSGISTAVE-TDFGLLV 437
L V ++LI ++V V V L +++YQSGI+ V+ + G+LV
Sbjct: 4539 LIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLV 4598
Query: 438 TFDGQHYASISVP-GSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHAD 496
+++G + S+ +P + N+T G CG DD + P G + + W V
Sbjct: 4599 SYNGLSF-SVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPS 4657
Query: 497 WKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLW---------ECGTVVDPTAFV 547
C + + + G + T PL +C +V P +
Sbjct: 4658 ---KPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYY 4714
Query: 548 HSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCT 607
+CV+D C + +L C ++QAYA +C I + DWR T V+CPS Y C
Sbjct: 4715 DACVFDSCFM-PGSSLECASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACG 4772
Query: 608 SSCPDTCSDLTASRNCATPCTEGCECNQGFV-LSTSQCVPLHKCGC-DFDGHYYTMGEFF 665
+ TC ++ +N T EGC C +G + + V + CGC D GE F
Sbjct: 4773 PAEEPTCKSSSSQQN-NTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHF 4831
Query: 666 WATANCTVQCLCEEGGD-VYCFNKTCGSGEVC-AVEDG 701
+C C+C EGG + C K C V VEDG
Sbjct: 4832 --EFDCK-NCVCLEGGSGIICQPKRCSQKPVTHCVEDG 4866
Score = 85.1 bits (209), Expect = 7e-16
Identities = 114/435 (26%), Positives = 173/435 (39%), Gaps = 59/435 (13%)
Query: 689 TCGSG-EVCAVEDGYQGCFPKRETVCLLSQNQVLH--TFDGASYAFPSEFSYTLLKTCPE 745
TC +G + VED GC E C + H TFDG Y++ +Y L++
Sbjct: 4455 TCSNGLQPVRVEDP-DGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISP 4513
Query: 746 RPEYLEIDINKKK--PDAGPAWLRGLRILVADQEVKIGGIGAS----EVKLNGQEVELPF 799
+ + I+ P+ + R L + QEV I + +V++N Q V LP+
Sbjct: 4514 SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPY 4573
Query: 800 FHPSGKLEIYRNKNSTTVESKGV-VTVQYSDIGLLYIRLSTTYF-NCTGGLCGFYNANAS 857
LE+Y++ + V+ + V V Y+ + +RL F N T G CG S
Sbjct: 4574 --KKYGLEVYQSGINYVVDIPELGVLVSYNGLSFS-VRLPYHRFGNNTKGQCGTCTNTTS 4630
Query: 858 DEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELL---------KFYRS 908
D+ LP+G+ N + W + C + + K
Sbjct: 4631 DDCILPSGEIVSNCEAAADQWLV-NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTP 4689
Query: 909 RSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNAD 968
C +I D S F +CH +V YY C+F C G+ E C S+ YA+ C +
Sbjct: 4690 SPLCQLIKD---SLFAQCHALVPPQHYYDACVFDSCFMPGSSLE-CASLQAYAALCAQQN 4745
Query: 969 VEVGPWR--TYDFCPLECPENSHFEECITCTETCETLTLGPICVDSCS--------EGCQ 1018
+ + WR T+ C +ECP + ++ C E P C S S EGC
Sbjct: 4746 ICL-DWRNHTHGACLVECPSHREYQACGPAEE--------PTCKSSSSQQNNTVLVEGCF 4796
Query: 1019 CDEG---YALLGSQCVTRSECGC-NFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCET 1074
C EG YA CV CGC + E F + DC+ C C + + C+
Sbjct: 4797 CPEGTMNYAPGFDVCV--KTCGCVGPDNVPREFGEHF--EFDCK-NCVCLEGGSGIICQP 4851
Query: 1075 IPC--KDDEYCMEEG 1087
C K +C+E+G
Sbjct: 4852 KRCSQKPVTHCVEDG 4866
Score = 67.8 bits (164), Expect = 1e-10
Identities = 88/411 (21%), Positives = 137/411 (33%), Gaps = 66/411 (16%)
Query: 1435 EPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRG---------CFSTKTS 1485
+ + +W DC C N ++ +C+ NG++ C+ +
Sbjct: 4420 QENETWWLCDCFM-ATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECD 4478
Query: 1486 -YCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINF-----DKWSAPNL 1539
YC G + TFDG + + NC +VL D I N+ DK S P
Sbjct: 4479 CYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRT 4538
Query: 1540 TIISPVYFYINEEQILINDRNT------VKVNGTQVNVPFITGLATKIYSSEGFLVIDTS 1593
I+ +++LI + V+VN V +P+ ++Y S V+D
Sbjct: 4539 LIVRH-----ETQEVLIKTVHMMPMQVQVQVNRQAVALPY-KKYGLEVYQSGINYVVDIP 4592
Query: 1594 P-DIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWK 1652
+ + YNG + R N G CG +DD + G+ V + A W
Sbjct: 4593 ELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWL 4652
Query: 1653 TNGMQKR--PLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDP 1710
N K P + S + + C + D F C+ L+ P
Sbjct: 4653 VNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKD--SLFAQCHALVPP 4710
Query: 1711 LPFYESCYLDGCYSHKKFQLCGSLAAYGEACRSFGILSTEW---------------IEKE 1755
+Y++C D C+ C SL AY C I +W E +
Sbjct: 4711 QHYYDACVFDSCFMPGSSLECASLQAYAALCAQQNI-CLDWRNHTHGACLVECPSHREYQ 4769
Query: 1756 NCSGVVEDPC-------------VGADCPNRTCELGNGREL----CGCIEP 1789
C E C G CP T G ++ CGC+ P
Sbjct: 4770 ACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGP 4820
>gi|239757284 PREDICTED: similar to Fc fragment of IgG binding
protein [Homo sapiens]
Length = 593
Score = 247 bits (631), Expect = 8e-65
Identities = 161/571 (28%), Positives = 240/571 (42%), Gaps = 87/571 (15%)
Query: 409 LPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNP 468
LPV L G ++ Q G +ETDFGL V +D +Y ++VPG+Y CGLCGNYN +P
Sbjct: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
Query: 469 LDDFLRPDGRPAMSVLDLGESWRVYHADWKC---------DSGCVDNCTQCDAATEALYF 519
DDF +P+G A + + G SW D C C+ + +C E Y
Sbjct: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPS-HKCPPELEKKYQ 121
Query: 520 GSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALG 579
++CG L+ GPL C +VDP + C++DLC N ++LC I AY CQA G
Sbjct: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
Query: 580 IPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVL 639
+ WRT+T C ++CP SHY +C +C CS L+A C C EGC+C+ GF+
Sbjct: 182 GHVEPWRTETFC--PMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLY 239
Query: 640 STSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVE 699
+ CVP+ +CGC +G YY E NC QC C G V C +C G+VC
Sbjct: 240 NGQACVPIQQCGCYHNGVYYE-PEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPS 298
Query: 700 DGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLL----------------KTC 743
G C K V L S Q +GA+ + + LL +TC
Sbjct: 299 GGILSCVTK---VTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETC 355
Query: 744 PER-------------------PEYLEID------------------------------- 753
E+ P Y D
Sbjct: 356 KEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 415
Query: 754 -INKKKPDAGPA--WLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYR 810
K + PA ++R + + + I +V++NG LP G++ + +
Sbjct: 416 VTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQ 475
Query: 811 NKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDN 870
+ + + + V Y + + L ++Y GLCG + N +++ PNG +
Sbjct: 476 GASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPS 535
Query: 871 LAVFLESWTT--FEEICNGECGDLLKACNND 899
+ ++ SW ++ +C EC C D
Sbjct: 536 IPIWGGSWRAPGWDPLCWDECRGSCPTCPED 566
Score = 246 bits (628), Expect = 2e-64
Identities = 166/568 (29%), Positives = 249/568 (43%), Gaps = 79/568 (13%)
Query: 795 VELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNA 854
++LP +G++ ++ + +E+ + V Y + + + + Y+ GLCG YN
Sbjct: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
Query: 855 NASDEFCLPNGKCTDNLAVFLESWTTFEEI-----------CNGECGDLLKACNNDSELL 903
+ D+F PNG N F SW EE+ C D + + EL
Sbjct: 61 DPKDDFQKPNGSQAGNANEFGNSW---EEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELE 117
Query: 904 KFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASA 963
K Y+ CG+++ P+ CH +V+ + C+F LC GGN S LC ++ Y SA
Sbjct: 118 KKYQKEEFCGLLSSPTGP-LSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSA 176
Query: 964 CKNADVEVGPWRTYDFCPLECPENSHFEECI-TCTETCETLTLGPIC------------- 1009
C+ A V PWRT FCP+ECP NSH+E C TC+ C L+ P C
Sbjct: 177 CQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSG 236
Query: 1010 ------------------------------VDSCSEGCQCDEGYALLGSQCVTRSECGCN 1039
+D+C + C C G ++ + + C
Sbjct: 237 FLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQ 296
Query: 1040 FEGHQLA--TNETF------WVDLDCQIFCYCSGTDNRV--------HCETIPCKDDEYC 1083
G L+ T T VD++ Y +G +V C + C+ E C
Sbjct: 297 PSGGILSCVTKVTLRSLAQTGVDVEGAAILY-NGQPLKVLLPLLSPDPCHGVTCRPQETC 355
Query: 1084 MEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRP-SSDSFPKFV 1142
E+GG C +A+C + G HY +FDG FDFQ +C +L TTG S+ F
Sbjct: 356 KEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 415
Query: 1143 VTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFS 1202
VT KN++R +V+ V V G +I IH+ V VN LP+ + G+I++
Sbjct: 416 VTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQ 475
Query: 1203 FGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASS 1262
++ DFGL+V YDW + +T+P S + GLCG + NP++D P G LA S
Sbjct: 476 GASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPS 535
Query: 1263 VNEFGQSWVKR--DTFCQVGCGDRCPSC 1288
+ +G SW D C C CP+C
Sbjct: 536 IPIWGGSWRAPGWDPLCWDECRGSCPTC 563
Score = 246 bits (628), Expect = 2e-64
Identities = 120/315 (38%), Positives = 163/315 (51%), Gaps = 11/315 (3%)
Query: 1189 LPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNP 1248
LP+ L G+I G VV+ETDFGL+V YD ++ +TVP + GLCG YNG+P
Sbjct: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
Query: 1249 DDDLEMPMGLLASSVNEFGQSWVK--------RDTFCQVGCGDRCPS--CA-KVEGFSKV 1297
DD + P G A + NEFG SW + T C G D PS C ++E +
Sbjct: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQK 122
Query: 1298 QQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGI 1357
++ C L+ + S CH V+P K+C+FD C+ GG + CS + Y S CQ G
Sbjct: 123 EEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGG 182
Query: 1358 TVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGK 1417
V WR T C + CPPNSHYE C C C+A+ C C EGC CD+G++ NG+
Sbjct: 183 HVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQ 242
Query: 1418 SCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVR 1477
+C+ CGCY +G YYEP+Q +C ++C C V+ C CK + C G+
Sbjct: 243 ACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGIL 302
Query: 1478 GCFSTKTSYCLAAGG 1492
C + T LA G
Sbjct: 303 SCVTKVTLRSLAQTG 317
Score = 159 bits (401), Expect = 4e-38
Identities = 90/249 (36%), Positives = 134/249 (53%), Gaps = 4/249 (1%)
Query: 294 CQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQ-C 352
C +C P E C+ +G C +TC ++G+PHYH+FDG F FQG+C Y+LA C
Sbjct: 344 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 403
Query: 353 --LQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLP 410
+ T L F+V KN++R AVS+V+ ++V G I I K G+V+VN ++T+LP
Sbjct: 404 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 463
Query: 411 VTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLD 470
V++ G + + Q + DFGL V++D +++P SY + CGLCGN ++NP +
Sbjct: 464 VSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 523
Query: 471 DFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKT 530
D + P+G A S+ G SWR D C C +C C Y G D G L+
Sbjct: 524 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGLDE-GSLSDH 582
Query: 531 DGPLWECGT 539
++ C T
Sbjct: 583 KDKIFMCYT 591
Score = 67.8 bits (164), Expect = 1e-10
Identities = 52/218 (23%), Positives = 87/218 (39%), Gaps = 31/218 (14%)
Query: 1588 LVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVL 1647
+VI+T +++ Y+ +++++ ++CGLCGN+NGD DD+ G ++
Sbjct: 21 VVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEF 80
Query: 1648 AQSWK-----TNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQ 1702
SW+ + + P P + S C +K Q + +C L+ G
Sbjct: 81 GNSWEEVVPDSPCLPPTPCPPGSEDCIPSH---KCPPELEKKYQKEEFCGLLSSPTGPLS 137
Query: 1703 PCYGLLDPLPFYESCYLDGCYSHKKFQ-LCGSLAAYGEACRSFGILSTEWIEKENCSGVV 1761
C+ L+DP + C D C LC ++ AY AC++ G W + C
Sbjct: 138 SCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP--- 194
Query: 1762 EDPCVGADCPNR--------TCELGNGRELCGCIEPPP 1791
+CP TC LG C + PP
Sbjct: 195 ------MECPPNSHYELCADTCSLG-----CSALSAPP 221
Score = 38.5 bits (88), Expect = 0.072
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYC 314
GC G + + D NC +C C + CQE SC P +VC+P G C
Sbjct: 251 GCYHNGVYYEPEQTVLID-NCRQQCTC-HAGKVVVCQEHSCKPGQVCQPSGGILSC 304
>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2852
Score = 237 bits (605), Expect = 8e-62
Identities = 210/797 (26%), Positives = 321/797 (40%), Gaps = 105/797 (13%)
Query: 707 PKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWL 766
P+R+++C + TFDG Y + SYTL+ + I ++ P G +
Sbjct: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHND-PQCGSSPY 131
Query: 767 RGLRIL----VADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGV 822
R + V +QE+ + A EV G V+LP H G + + V +
Sbjct: 132 TCSRAVSLFFVGEQEIHL----AKEVTHGGMRVQLP--HVMGSARLQQLAGYVIVRHQSA 185
Query: 823 VTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFE 882
T+ + +YI++S T GLCG NA+ D+ +GK TD++ F+ SW E
Sbjct: 186 FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ--E 243
Query: 883 EICNGECGDLLKAC-------NNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAY 935
+ N G + N + Y +C + P F CH V+ +
Sbjct: 244 QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY---EQCEALLRP---PFDACHAYVSPLPF 297
Query: 936 YRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRT-YDFCPLECPENSH-FEEC 993
+C LCQS G+ + C ++A YA AC A + WRT C + C E + + EC
Sbjct: 298 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 357
Query: 994 IT-CTETCETLTLGPICVDS---CSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNE 1049
I C +C CVDS C +GC C G CV +EC C F G
Sbjct: 358 IACCPASCHPRA---SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGS 414
Query: 1050 TFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYL 1109
V DC C+ T + C T C A C V+G H+
Sbjct: 415 V--VKEDCNT---CTCTSGKWECSTAVC-------------------PAECSVTGDIHFT 450
Query: 1110 TFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYS 1169
TFDG + F +C IL S S F VT +N + Q V S
Sbjct: 451 TFDGRRYTFPATCQYILA------KSRSSGTFTVTLQN------APCGLNQDGACVQSVS 498
Query: 1170 IVIHRAYKHTV---------LVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYD 1220
+++H+ + V L + ++ P +I S F + V T+ G++V+YD
Sbjct: 499 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVF-LRVRTNVGVRVLYD 557
Query: 1221 WKTF-LSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQV 1279
+ L + V + T GLCG +NGN DD P+G+ S+ FG SW +
Sbjct: 558 REGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPL 617
Query: 1280 GCGDRCPSC-AKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAV 1338
G C ++ S Q CS++ + F+ C + ++P +++ C D+C G
Sbjct: 618 VSGSPLDPCDVHLQAASYSVQACSVLTGE--MFAPCSAFLSPVPYFEQCRRDACRCG--Q 673
Query: 1339 QTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDC 1398
C+ L +YA C+ G+ V +C ++C + Y CV+ C C + C
Sbjct: 674 PCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEAC 733
Query: 1399 S---------HYCVEGCHCDAGYVLNGKS--CILPHSCGCYSDGKYYEPKQLFWNSDCTR 1447
CVEGC C L+ ++ C+ + C C+ G Y P +SD
Sbjct: 734 GVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP----GDSDIPS 789
Query: 1448 --RCRCFRRNVIQCDPR 1462
C C + V+ CD R
Sbjct: 790 LGHCHC-KDGVMSCDSR 805
Score = 202 bits (513), Expect = 4e-51
Identities = 200/816 (24%), Positives = 318/816 (38%), Gaps = 78/816 (9%)
Query: 285 CLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVET-STCVVFGEPHYHTFDGFLFHFQGS 343
C + ++ C + P+ + Y + E S C +G+ H TFDG ++ G
Sbjct: 41 CFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGK 100
Query: 344 CAY-LLARQCLQTSSLPFFSVEAKNEHRRGSA-VSWVKELSVEVNGYKI--LIPKGSYGR 399
+Y L+ R + S FS++ N+ + GS+ + + +S+ G + L + ++G
Sbjct: 101 GSYTLVGRHEPEGQS---FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGG 157
Query: 400 VKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCG 459
++V LP + G+ ++ Q V + +DG I + + T G
Sbjct: 158 MRVQ-----LPHVM--GSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHG 210
Query: 460 LCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK----CDSGCVDNCTQCDAAT- 514
LCGN N +P DD + G+ V++ SW+ + S C Q + T
Sbjct: 211 LCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTM 270
Query: 515 EALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALV 574
+ +Y + C L + P C V P F SC DLC + C+A+ YA
Sbjct: 271 QGVY---EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARA 325
Query: 575 CQALGIPIGDWRTQTGCVSTVQCPSFSH-YSVCTSSCPDTCSDLTASRNCATPCTEGCEC 633
C G P+ WRTQ TV C + Y+ C + CP +C + + C +GC C
Sbjct: 326 CAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYC 384
Query: 634 NQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSG 693
G + CV +C C+F G Y G N C C G K S
Sbjct: 385 PNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCN---TCTCTSG-------KWECST 434
Query: 694 EVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEID 753
VC E C ++ + TFDG Y FP+ Y L K+ + +
Sbjct: 435 AVCPAE-------------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQ 481
Query: 754 INKKKPDAGPAWLRGLRILV-ADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYR-N 811
+ A ++ + +++ D ++ A +V L Q +P + EI R +
Sbjct: 482 NAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPY-TDDAFEIRRLS 540
Query: 812 KNSTTVESKGVVTVQYSDIGL-LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDN 870
V + V V Y GL LY+++ + T GLCG +N N D+F P G
Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
Query: 871 LAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVV 930
+F SW T G L C D L S C ++ + F C +
Sbjct: 601 PQLFGNSWKTLSACSPLVSGSPLDPC--DVHLQAASYSVQACSVL---TGEMFAPCSAFL 655
Query: 931 NVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHF 990
+ Y+ C C+ G + LC ++A YA C+ + V C L C + +
Sbjct: 656 SPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEY 713
Query: 991 EECIT-CTETCETLTLGPIC---------VDSCSEGCQC--DEGYALLGSQCVTRSECGC 1038
C+ C TC+ L C D C EGC C D CV R++C C
Sbjct: 714 SPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 773
Query: 1039 NFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCET 1074
+F+G ++ D+ C+C D + C++
Sbjct: 774 HFQGVDYPPGDS---DIPSLGHCHCK--DGVMSCDS 804
Score = 182 bits (461), Expect = 4e-45
Identities = 185/718 (25%), Positives = 268/718 (37%), Gaps = 72/718 (10%)
Query: 1089 LYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNE 1148
+Y D+ C G H TFDG + L P SF + N+
Sbjct: 68 VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR-HEPEGQSFS---IQVHND 123
Query: 1149 DRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVV 1208
+ S + F IH A + V R+ LP +G ++ +V+
Sbjct: 124 PQCGSSPYTCSRAVSLFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQ--QLAGYVI 179
Query: 1209 VETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQ 1268
V + +D + + I + + T+GLCG N +P DDL G L V EF
Sbjct: 180 VRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVH 239
Query: 1269 SWVKRDTFCQVGCGDRC---PSCAKVEG--FSKVQQLCSLIPNQNAAFSKCHSKVNPTFF 1323
SW ++ G P C + V + C + F CH+ V+P F
Sbjct: 240 SWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL--LRPPFDACHAYVSPLPF 297
Query: 1324 YKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYT-SCTVTCPPNSH-YESC 1381
+C D C G V T C L YA C G + GWR CTV C + Y C
Sbjct: 298 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 357
Query: 1382 VSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW 1441
++ C C D CV+GC+C G + C+ P C C G Y P +
Sbjct: 358 IACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVV- 416
Query: 1442 NSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGA 1501
DC C C +C C ++ C G F TFDG
Sbjct: 417 KEDCNT-CTC-TSGKWECSTAVCPAE-------------------CSVTGDIHFTTFDGR 455
Query: 1502 FLRFPANCAFVLS------TICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQIL 1555
FPA C ++L+ T L + L N D ++++I Q+
Sbjct: 456 RYTFPATCQYILAKSRSSGTFTVTLQNAPCGL--NQDGACVQSVSVI---LHQDPRRQVT 510
Query: 1556 INDRNTVKVNGTQVNVPFITGLATKIYS-SEGFLVIDTSPDIQIYYNGFNV-IKISISER 1613
+ V + +P T A +I S FL + T+ +++ Y+ + + + + +R
Sbjct: 511 LTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQR 570
Query: 1614 LQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQY 1673
GLCG FNG+ DD+++ G P + + SWKT +C+ L
Sbjct: 571 WVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT--------LSACSPLVSGSP 622
Query: 1674 AAMCDNVHIQKMQ-GDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQLCG 1732
CD VH+Q C LT F PC L P+P++E C D C + LC
Sbjct: 623 LDPCD-VHLQAASYSVQACSVLTG--EMFAPCSAFLSPVPYFEQCRRDACRCGQPC-LCA 678
Query: 1733 SLAAYGEACRSFGILSTEWIEKENCSGVVE-----DPCVGADCPNRTCELGNGRELCG 1785
+LA Y CR G+ C+ E PCV A C RTC+ E CG
Sbjct: 679 TLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV-APC-GRTCQDLASPEACG 734
Score = 134 bits (337), Expect = 1e-30
Identities = 118/453 (26%), Positives = 183/453 (40%), Gaps = 52/453 (11%)
Query: 254 IDPANGCTSRGQFLRRGEVFWDDLNCTVKCRC-LDFNNEIY---------CQEASCSPYE 303
+D C G + G +F +D C C +F+ +Y C +C+
Sbjct: 372 VDSEIACVD-GCYCPNGLIF-EDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCT--- 426
Query: 304 VCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSV 363
GK+ +AV + C V G+ H+ TFDG + F +C Y+LA+ + S F+V
Sbjct: 427 ----SGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTV 478
Query: 364 EAKNE----HRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVK 419
+N ++ G+ V V + + ++ + + G V + D +P D
Sbjct: 479 TLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA--GDVLLFDQYKIIPPYTDDAFEI 536
Query: 420 IYQSGISTAVETDFGLLVTFDGQHYAS-ISVPGSYINSTCGLCGNYNKNPLDDFLRPDGR 478
S + V T+ G+ V +D + + V ++ T GLCG +N N DDFL P G
Sbjct: 537 RRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGV 596
Query: 479 PAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECG 538
P + G SW+ A SG CD +A + C L T C
Sbjct: 597 PESTPQLFGNSWKTLSACSPLVSG--SPLDPCDVHLQAASYSVQACSVL--TGEMFAPCS 652
Query: 539 TVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCP 598
+ P + C D C R LC + YA +C+ G+P+ D+R + + + C
Sbjct: 653 AFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPV-DFRARLPACA-LSCE 708
Query: 599 SFSHYSVCTSSCPDTCSDLTASRNCAT---------PCTEGCECNQGFVLSTSQ--CVPL 647
+ YS C + C TC DL + C C EGC C L T CVP
Sbjct: 709 ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPR 768
Query: 648 HKCGCDFDGHYYTMGEFFWATANCTVQCLCEEG 680
++C C F G Y G+ + C C++G
Sbjct: 769 NQCSCHFQGVDYPPGD---SDIPSLGHCHCKDG 798
Score = 112 bits (279), Expect = 5e-24
Identities = 104/403 (25%), Positives = 158/403 (39%), Gaps = 57/403 (14%)
Query: 984 CPENSHFEEC--------ITCTETCET--LTLGPICVDSCSEGCQCDEGYALLGSQCVTR 1033
CP F C ++ TCE L L C GC C +G G C
Sbjct: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
Query: 1034 SECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQ 1093
EC C ++G + Y G C T C + G + C
Sbjct: 871 EECPCTWKGKE-----------------YFPGDQVMSPCHTCVC--------QRGSFQCT 905
Query: 1094 ARTDAS-CIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDP 1152
AS C G HY TFDG PFDF +C + L S S F V +N +
Sbjct: 906 LHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV------KSTSDVSFSVIVENVNCYS 959
Query: 1153 SLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVE-T 1211
S + K + + V G S+++ + S +L K +++ + GF +V
Sbjct: 960 SGMICRKFISINV-GNSLIV---FDDDSGNPSPESFLDDK---QEVHTWRVGFFTLVHFP 1012
Query: 1212 DFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWV 1271
+ +++D +T + + Q GLCG ++ +++ P L ++ EFG SW
Sbjct: 1013 QEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWA 1072
Query: 1272 KRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDS 1331
+ + D C E F+K + CS++ ++ F CH V+ T+FY NCL D+
Sbjct: 1073 AVECPDTLDPRDMCVLNPLREPFAKKE--CSILLSE--VFEICHPVVDVTWFYSNCLTDT 1128
Query: 1332 --CIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTC 1372
C GG + C+ + YA C G+ V WR C C
Sbjct: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 84.3 bits (207), Expect = 1e-15
Identities = 82/338 (24%), Positives = 128/338 (37%), Gaps = 27/338 (7%)
Query: 258 NGCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAV 317
+GC LR G+ + +C C E + + SP C + F C+
Sbjct: 852 SGCACPQGLLRHGDACF----LPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLH 907
Query: 318 E-TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVS 376
STC +G+ HY TFDG F F G+C L + S FSV +N + S +
Sbjct: 908 PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS----FSVIVENVNCYSSGMI 963
Query: 377 WVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVE-TDFGL 435
K +S+ V G +++ G + D V ++ G T V +
Sbjct: 964 CRKFISINV-GNSLIVFDDDSGNPSPESFLD------DKQEVHTWRVGFFTLVHFPQEHI 1016
Query: 436 LVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHA 495
+ +D + + + GLCGN++ +++ P+ + + G SW A
Sbjct: 1017 TLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW----A 1072
Query: 496 DWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLC 555
+C +D C F C L + C VVD T F +C+ D C
Sbjct: 1073 AVECPD-TLDPRDMCVLNPLREPFAKKECSILLSEVFEI--CHPVVDVTWFYSNCLTDTC 1129
Query: 556 SVRDNG--TLLCQAIQAYALVCQALGIPIGDWRTQTGC 591
G C ++ AYA C G+ + DWRT C
Sbjct: 1130 GCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLC 1166
Score = 72.4 bits (176), Expect = 4e-12
Identities = 92/403 (22%), Positives = 142/403 (35%), Gaps = 58/403 (14%)
Query: 597 CPSFSHYSVCTSSCPD-------TCSD--LTASRNCATPCTEGCECNQGFVLSTSQCVPL 647
CP+ + C+ D TC L S + PC GC C QG + C
Sbjct: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
Query: 648 HKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFP 707
+C C + G Y G+ + + C+C+ G C C S
Sbjct: 871 EECPCTWKGKEYFPGDQVMSPCHT---CVCQRGS-FQCTLHPCAS--------------- 911
Query: 708 KRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLR 767
C ++ TFDG + F L+K+ + + I N +G +
Sbjct: 912 ----TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD-VSFSVIVENVNCYSSGMICRK 966
Query: 768 GLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVE-SKGVVTVQ 826
+ I V + + +G F ++ +R T V + +T+
Sbjct: 967 FISINVGNSLIVFDDD-------SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLL 1019
Query: 827 YSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICN 886
+ ++++ + GLCG ++ +E P N F SW E
Sbjct: 1020 WDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVE---- 1075
Query: 887 GECGDLLKACNNDSELLKFYR---SRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRL 943
C D L D +L R ++ C I+ + F CH VV+VT +Y CL
Sbjct: 1076 --CPDTLDP--RDMCVLNPLREPFAKKECSIL---LSEVFEICHPVVDVTWFYSNCLTDT 1128
Query: 944 --CQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLEC 984
C GG+ C SV+ YA C V V WRT CP +C
Sbjct: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 70.5 bits (171), Expect = 2e-11
Identities = 70/286 (24%), Positives = 114/286 (39%), Gaps = 30/286 (10%)
Query: 831 GLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCT---DNLAVFLESWTTFEEICN- 886
GL+ + S T GLCG + +A+++ L +G ++ A FL+SW + +
Sbjct: 2158 GLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSV 2217
Query: 887 GECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQS 946
G+ +C S C + SN +F CH V ++ + +
Sbjct: 2218 GQTRFRPDSCATTD--------CSPC--LRMVSNRTFSACHRFVPPESFCELWI----RD 2263
Query: 947 GGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECITCTE---TCETL 1003
+ C ++ Y + C V + WR D+CP C +S ++ C+T E TC+
Sbjct: 2264 TKYVQQPCVALTVYVAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG 2322
Query: 1004 TLGPICVDSC---SEGCQCDEGYAL---LGSQCVTRSECGC-NFEGHQLATNETFWVDLD 1056
LGP+ + C EGC C EG L + C+ ++C C + G A ET+ L
Sbjct: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
Query: 1057 CQIFCYCSGTDNRVHCET-IPCKDDEYCMEEGGLYYCQARTDASCI 1101
C D V + P E C+ G + D C+
Sbjct: 2383 GCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2428
Score = 70.1 bits (170), Expect = 2e-11
Identities = 79/361 (21%), Positives = 128/361 (35%), Gaps = 49/361 (13%)
Query: 1402 CVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDP 1461
C+ GC C G + +G +C LP C C GK Y P S C C C +R QC
Sbjct: 850 CLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM-SPC-HTCVC-QRGSFQCTL 906
Query: 1462 RQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLP 1521
C S C A G +RTFDG F C L +
Sbjct: 907 HPC-------------------ASTCTAYGDRHYRTFDGLPFDFVGACKVHL---VKSTS 944
Query: 1522 DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKI 1581
D+SF +I+ + + + + I+ +D +G F+
Sbjct: 945 DVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDD-----SGNPSPESFLDDKQEVH 999
Query: 1582 YSSEGFLVIDTSPD--IQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGK 1639
GF + P I + ++ + + + Q ++ GLCGNF+ ++ T
Sbjct: 1000 TWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENL 1059
Query: 1640 PVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKG 1699
+ + SW A C + + MC +++ C L +
Sbjct: 1060 ELTNPQEFGSSW---------AAVECPDTLDPR--DMCVLNPLREPFAKKECSIL--LSE 1106
Query: 1700 FFQPCYGLLDPLPFYESCYLDGCYSHKKFQ---LCGSLAAYGEACRSFGILSTEWIEKEN 1756
F+ C+ ++D FY +C D C + C S++AY C G+ + +W
Sbjct: 1107 VFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGV-AVDWRTPRL 1165
Query: 1757 C 1757
C
Sbjct: 1166 C 1166
Score = 68.2 bits (165), Expect = 8e-11
Identities = 81/368 (22%), Positives = 138/368 (37%), Gaps = 44/368 (11%)
Query: 1161 VDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYD 1220
+++T + + I R + V V+ + ++ P+ +I + ++ +D ++ ++
Sbjct: 2098 LNMTHLAHQVTIDR-FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHS 2156
Query: 1221 WKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNE---FGQSWVKRDTFC 1277
+ + ++ + +GLCG +G+ +DL + G + + F SW +
Sbjct: 2157 -SGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLT 2215
Query: 1278 QVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGA 1337
VG P S ++ S N FS CH V P F + + D+
Sbjct: 2216 SVGQTRFRPDSCATTDCSPCLRMVS-----NRTFSACHRFVPPESFCELWIRDTKY---- 2266
Query: 1338 VQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQP--RCA-AIRL 1394
VQ C L Y + C + + WR C C +S Y++CV+ C+P C I
Sbjct: 2267 VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILG 2325
Query: 1395 KSDCSHYCV--EGCHCDAGYVLNGKS---CILPHSCGCYSDGKYYEPKQLFWNSDCTRRC 1449
D H V EGC C G +L+ + CI C C WNS + C
Sbjct: 2326 PLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
Query: 1450 RCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANC 1509
+ QC++ + + GC S + CL F L P
Sbjct: 2386 Q-----------HQCQAPDTIVPVD--LGCPSPRPESCL--------RFGEVALLLPTKD 2424
Query: 1510 AFVLSTIC 1517
L T+C
Sbjct: 2425 PCCLGTVC 2432
Score = 40.4 bits (93), Expect = 0.019
Identities = 69/305 (22%), Positives = 111/305 (36%), Gaps = 50/305 (16%)
Query: 1495 FRTFDGAFLRFPANCAFVLSTICQKLPDISF----QLIINFDKWSAPNLTIISPVYFYIN 1550
F TFDG+ + ++LS ++ + + W L +++ +
Sbjct: 2047 FVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHL--- 2103
Query: 1551 EEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYY---NGFNVIK 1607
Q+ I+ N Q P ++ +I + +I T DIQI + +G +++
Sbjct: 2104 AHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVE 2163
Query: 1608 ISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSS----VVLAQSWK-----TNGMQK 1658
S + + Q GLCG +GD +D +TL+ VV SW+ T+ Q
Sbjct: 2164 ASKTSKAQGH--GLCGICDGDAAND-LTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
Query: 1659 RPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCY 1718
R SC S CL++ + F C+ + P F E
Sbjct: 2221 RFRPDSCATTDCSP------------------CLRMVSNR-TFSACHRFVPPESFCELWI 2261
Query: 1719 LDGCYSHKKFQLCGSLAAYGEACRSFGILSTEWIEKENC-----SGVVEDPCVGADCPNR 1773
D Y Q C +L Y C F + EW + C S CV A P +
Sbjct: 2262 RDTKYVQ---QPCVALTVYVAMCHKFHV-CIEWRRSDYCPFLCSSDSTYQACVTACEPPK 2317
Query: 1774 TCELG 1778
TC+ G
Sbjct: 2318 TCQDG 2322
Score = 38.9 bits (89), Expect = 0.055
Identities = 60/294 (20%), Positives = 97/294 (32%), Gaps = 77/294 (26%)
Query: 459 GLCGNYNKNPLDDFLRPDGRPAMSVLDLG---ESWRVYHA-------DWKCDSGCVDNCT 508
GLCG + + +D DG D +SW+V + ++ DS +C+
Sbjct: 2174 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCS 2233
Query: 509 QCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAI 568
C F + C V P +F + D V+ C A+
Sbjct: 2234 PCLRMVSNRTFSA---------------CHRFVPPESFCELWIRDTKYVQQP----CVAL 2274
Query: 569 QAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCT 628
Y +C + I +WR + CP CS + + C T C
Sbjct: 2275 TVYVAMCHKFHVCI-EWRR-------------------SDYCPFLCSSDSTYQACVTACE 2314
Query: 629 ----------------------EGCECNQGFVL---STSQCVPLHKCGC-DFDGHYYTMG 662
EGC C++G +L ++ C+P KC C D G +G
Sbjct: 2315 PPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALG 2374
Query: 663 EFFWATANCTVQCLCEEGGDVYCFNKTCGS--GEVCAVEDGYQGCFPKRETVCL 714
E + ++ + Q C+ + + C S E C P ++ CL
Sbjct: 2375 ETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2428
>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2924
Score = 237 bits (605), Expect = 8e-62
Identities = 210/797 (26%), Positives = 321/797 (40%), Gaps = 105/797 (13%)
Query: 707 PKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWL 766
P+R+++C + TFDG Y + SYTL+ + I ++ P G +
Sbjct: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHND-PQCGSSPY 203
Query: 767 RGLRIL----VADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGV 822
R + V +QE+ + A EV G V+LP H G + + V +
Sbjct: 204 TCSRAVSLFFVGEQEIHL----AKEVTHGGMRVQLP--HVMGSARLQQLAGYVIVRHQSA 257
Query: 823 VTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFE 882
T+ + +YI++S T GLCG NA+ D+ +GK TD++ F+ SW E
Sbjct: 258 FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ--E 315
Query: 883 EICNGECGDLLKAC-------NNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAY 935
+ N G + N + Y +C + P F CH V+ +
Sbjct: 316 QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY---EQCEALLRP---PFDACHAYVSPLPF 369
Query: 936 YRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRT-YDFCPLECPENSH-FEEC 993
+C LCQS G+ + C ++A YA AC A + WRT C + C E + + EC
Sbjct: 370 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 429
Query: 994 IT-CTETCETLTLGPICVDS---CSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNE 1049
I C +C CVDS C +GC C G CV +EC C F G
Sbjct: 430 IACCPASCHPRA---SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGS 486
Query: 1050 TFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYL 1109
V DC C+ T + C T C A C V+G H+
Sbjct: 487 V--VKEDCNT---CTCTSGKWECSTAVC-------------------PAECSVTGDIHFT 522
Query: 1110 TFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYS 1169
TFDG + F +C IL S S F VT +N + Q V S
Sbjct: 523 TFDGRRYTFPATCQYILA------KSRSSGTFTVTLQN------APCGLNQDGACVQSVS 570
Query: 1170 IVIHRAYKHTV---------LVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYD 1220
+++H+ + V L + ++ P +I S F + V T+ G++V+YD
Sbjct: 571 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVF-LRVRTNVGVRVLYD 629
Query: 1221 WKTF-LSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQV 1279
+ L + V + T GLCG +NGN DD P+G+ S+ FG SW +
Sbjct: 630 REGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPL 689
Query: 1280 GCGDRCPSC-AKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAV 1338
G C ++ S Q CS++ + F+ C + ++P +++ C D+C G
Sbjct: 690 VSGSPLDPCDVHLQAASYSVQACSVLTGE--MFAPCSAFLSPVPYFEQCRRDACRCG--Q 745
Query: 1339 QTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDC 1398
C+ L +YA C+ G+ V +C ++C + Y CV+ C C + C
Sbjct: 746 PCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEAC 805
Query: 1399 S---------HYCVEGCHCDAGYVLNGKS--CILPHSCGCYSDGKYYEPKQLFWNSDCTR 1447
CVEGC C L+ ++ C+ + C C+ G Y P +SD
Sbjct: 806 GVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP----GDSDIPS 861
Query: 1448 --RCRCFRRNVIQCDPR 1462
C C + V+ CD R
Sbjct: 862 LGHCHC-KDGVMSCDSR 877
Score = 202 bits (513), Expect = 4e-51
Identities = 200/816 (24%), Positives = 318/816 (38%), Gaps = 78/816 (9%)
Query: 285 CLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVET-STCVVFGEPHYHTFDGFLFHFQGS 343
C + ++ C + P+ + Y + E S C +G+ H TFDG ++ G
Sbjct: 113 CFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGK 172
Query: 344 CAY-LLARQCLQTSSLPFFSVEAKNEHRRGSA-VSWVKELSVEVNGYKI--LIPKGSYGR 399
+Y L+ R + S FS++ N+ + GS+ + + +S+ G + L + ++G
Sbjct: 173 GSYTLVGRHEPEGQS---FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGG 229
Query: 400 VKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCG 459
++V LP + G+ ++ Q V + +DG I + + T G
Sbjct: 230 MRVQ-----LPHVM--GSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHG 282
Query: 460 LCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK----CDSGCVDNCTQCDAAT- 514
LCGN N +P DD + G+ V++ SW+ + S C Q + T
Sbjct: 283 LCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTM 342
Query: 515 EALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALV 574
+ +Y + C L + P C V P F SC DLC + C+A+ YA
Sbjct: 343 QGVY---EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARA 397
Query: 575 CQALGIPIGDWRTQTGCVSTVQCPSFSH-YSVCTSSCPDTCSDLTASRNCATPCTEGCEC 633
C G P+ WRTQ TV C + Y+ C + CP +C + + C +GC C
Sbjct: 398 CAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYC 456
Query: 634 NQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSG 693
G + CV +C C+F G Y G N C C G K S
Sbjct: 457 PNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCN---TCTCTSG-------KWECST 506
Query: 694 EVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEID 753
VC E C ++ + TFDG Y FP+ Y L K+ + +
Sbjct: 507 AVCPAE-------------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQ 553
Query: 754 INKKKPDAGPAWLRGLRILV-ADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYR-N 811
+ A ++ + +++ D ++ A +V L Q +P + EI R +
Sbjct: 554 NAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPY-TDDAFEIRRLS 612
Query: 812 KNSTTVESKGVVTVQYSDIGL-LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDN 870
V + V V Y GL LY+++ + T GLCG +N N D+F P G
Sbjct: 613 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 672
Query: 871 LAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVV 930
+F SW T G L C D L S C ++ + F C +
Sbjct: 673 PQLFGNSWKTLSACSPLVSGSPLDPC--DVHLQAASYSVQACSVL---TGEMFAPCSAFL 727
Query: 931 NVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHF 990
+ Y+ C C+ G + LC ++A YA C+ + V C L C + +
Sbjct: 728 SPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEY 785
Query: 991 EECIT-CTETCETLTLGPIC---------VDSCSEGCQC--DEGYALLGSQCVTRSECGC 1038
C+ C TC+ L C D C EGC C D CV R++C C
Sbjct: 786 SPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 845
Query: 1039 NFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCET 1074
+F+G ++ D+ C+C D + C++
Sbjct: 846 HFQGVDYPPGDS---DIPSLGHCHCK--DGVMSCDS 876
Score = 182 bits (461), Expect = 4e-45
Identities = 185/718 (25%), Positives = 268/718 (37%), Gaps = 72/718 (10%)
Query: 1089 LYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNE 1148
+Y D+ C G H TFDG + L P SF + N+
Sbjct: 140 VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR-HEPEGQSFS---IQVHND 195
Query: 1149 DRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVV 1208
+ S + F IH A + V R+ LP +G ++ +V+
Sbjct: 196 PQCGSSPYTCSRAVSLFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQ--QLAGYVI 251
Query: 1209 VETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQ 1268
V + +D + + I + + T+GLCG N +P DDL G L V EF
Sbjct: 252 VRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVH 311
Query: 1269 SWVKRDTFCQVGCGDRC---PSCAKVEG--FSKVQQLCSLIPNQNAAFSKCHSKVNPTFF 1323
SW ++ G P C + V + C + F CH+ V+P F
Sbjct: 312 SWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL--LRPPFDACHAYVSPLPF 369
Query: 1324 YKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYT-SCTVTCPPNSH-YESC 1381
+C D C G V T C L YA C G + GWR CTV C + Y C
Sbjct: 370 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 429
Query: 1382 VSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW 1441
++ C C D CV+GC+C G + C+ P C C G Y P +
Sbjct: 430 IACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVV- 488
Query: 1442 NSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGA 1501
DC C C +C C ++ C G F TFDG
Sbjct: 489 KEDCNT-CTC-TSGKWECSTAVCPAE-------------------CSVTGDIHFTTFDGR 527
Query: 1502 FLRFPANCAFVLS------TICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQIL 1555
FPA C ++L+ T L + L N D ++++I Q+
Sbjct: 528 RYTFPATCQYILAKSRSSGTFTVTLQNAPCGL--NQDGACVQSVSVI---LHQDPRRQVT 582
Query: 1556 INDRNTVKVNGTQVNVPFITGLATKIYS-SEGFLVIDTSPDIQIYYNGFNV-IKISISER 1613
+ V + +P T A +I S FL + T+ +++ Y+ + + + + +R
Sbjct: 583 LTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQR 642
Query: 1614 LQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQY 1673
GLCG FNG+ DD+++ G P + + SWKT +C+ L
Sbjct: 643 WVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT--------LSACSPLVSGSP 694
Query: 1674 AAMCDNVHIQKMQ-GDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQLCG 1732
CD VH+Q C LT F PC L P+P++E C D C + LC
Sbjct: 695 LDPCD-VHLQAASYSVQACSVLTG--EMFAPCSAFLSPVPYFEQCRRDACRCGQPC-LCA 750
Query: 1733 SLAAYGEACRSFGILSTEWIEKENCSGVVE-----DPCVGADCPNRTCELGNGRELCG 1785
+LA Y CR G+ C+ E PCV A C RTC+ E CG
Sbjct: 751 TLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV-APC-GRTCQDLASPEACG 806
Score = 134 bits (337), Expect = 1e-30
Identities = 118/453 (26%), Positives = 183/453 (40%), Gaps = 52/453 (11%)
Query: 254 IDPANGCTSRGQFLRRGEVFWDDLNCTVKCRC-LDFNNEIY---------CQEASCSPYE 303
+D C G + G +F +D C C +F+ +Y C +C+
Sbjct: 444 VDSEIACVD-GCYCPNGLIF-EDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCT--- 498
Query: 304 VCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSV 363
GK+ +AV + C V G+ H+ TFDG + F +C Y+LA+ + S F+V
Sbjct: 499 ----SGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTV 550
Query: 364 EAKNE----HRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVK 419
+N ++ G+ V V + + ++ + + G V + D +P D
Sbjct: 551 TLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA--GDVLLFDQYKIIPPYTDDAFEI 608
Query: 420 IYQSGISTAVETDFGLLVTFDGQHYAS-ISVPGSYINSTCGLCGNYNKNPLDDFLRPDGR 478
S + V T+ G+ V +D + + V ++ T GLCG +N N DDFL P G
Sbjct: 609 RRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGV 668
Query: 479 PAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECG 538
P + G SW+ A SG CD +A + C L T C
Sbjct: 669 PESTPQLFGNSWKTLSACSPLVSG--SPLDPCDVHLQAASYSVQACSVL--TGEMFAPCS 724
Query: 539 TVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCP 598
+ P + C D C R LC + YA +C+ G+P+ D+R + + + C
Sbjct: 725 AFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPV-DFRARLPACA-LSCE 780
Query: 599 SFSHYSVCTSSCPDTCSDLTASRNCAT---------PCTEGCECNQGFVLSTSQ--CVPL 647
+ YS C + C TC DL + C C EGC C L T CVP
Sbjct: 781 ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPR 840
Query: 648 HKCGCDFDGHYYTMGEFFWATANCTVQCLCEEG 680
++C C F G Y G+ + C C++G
Sbjct: 841 NQCSCHFQGVDYPPGD---SDIPSLGHCHCKDG 870
Score = 112 bits (279), Expect = 5e-24
Identities = 104/403 (25%), Positives = 158/403 (39%), Gaps = 57/403 (14%)
Query: 984 CPENSHFEEC--------ITCTETCET--LTLGPICVDSCSEGCQCDEGYALLGSQCVTR 1033
CP F C ++ TCE L L C GC C +G G C
Sbjct: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 942
Query: 1034 SECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQ 1093
EC C ++G + Y G C T C + G + C
Sbjct: 943 EECPCTWKGKE-----------------YFPGDQVMSPCHTCVC--------QRGSFQCT 977
Query: 1094 ARTDAS-CIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDP 1152
AS C G HY TFDG PFDF +C + L S S F V +N +
Sbjct: 978 LHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV------KSTSDVSFSVIVENVNCYS 1031
Query: 1153 SLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVE-T 1211
S + K + + V G S+++ + S +L K +++ + GF +V
Sbjct: 1032 SGMICRKFISINV-GNSLIV---FDDDSGNPSPESFLDDK---QEVHTWRVGFFTLVHFP 1084
Query: 1212 DFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWV 1271
+ +++D +T + + Q GLCG ++ +++ P L ++ EFG SW
Sbjct: 1085 QEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWA 1144
Query: 1272 KRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDS 1331
+ + D C E F+K + CS++ ++ F CH V+ T+FY NCL D+
Sbjct: 1145 AVECPDTLDPRDMCVLNPLREPFAKKE--CSILLSE--VFEICHPVVDVTWFYSNCLTDT 1200
Query: 1332 --CIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTC 1372
C GG + C+ + YA C G+ V WR C C
Sbjct: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 84.3 bits (207), Expect = 1e-15
Identities = 82/338 (24%), Positives = 128/338 (37%), Gaps = 27/338 (7%)
Query: 258 NGCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAV 317
+GC LR G+ + +C C E + + SP C + F C+
Sbjct: 924 SGCACPQGLLRHGDACF----LPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLH 979
Query: 318 E-TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVS 376
STC +G+ HY TFDG F F G+C L + S FSV +N + S +
Sbjct: 980 PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS----FSVIVENVNCYSSGMI 1035
Query: 377 WVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVE-TDFGL 435
K +S+ V G +++ G + D V ++ G T V +
Sbjct: 1036 CRKFISINV-GNSLIVFDDDSGNPSPESFLD------DKQEVHTWRVGFFTLVHFPQEHI 1088
Query: 436 LVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHA 495
+ +D + + + GLCGN++ +++ P+ + + G SW A
Sbjct: 1089 TLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW----A 1144
Query: 496 DWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLC 555
+C +D C F C L + C VVD T F +C+ D C
Sbjct: 1145 AVECPD-TLDPRDMCVLNPLREPFAKKECSILLSEVFEI--CHPVVDVTWFYSNCLTDTC 1201
Query: 556 SVRDNG--TLLCQAIQAYALVCQALGIPIGDWRTQTGC 591
G C ++ AYA C G+ + DWRT C
Sbjct: 1202 GCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLC 1238
Score = 72.4 bits (176), Expect = 4e-12
Identities = 92/403 (22%), Positives = 142/403 (35%), Gaps = 58/403 (14%)
Query: 597 CPSFSHYSVCTSSCPD-------TCSD--LTASRNCATPCTEGCECNQGFVLSTSQCVPL 647
CP+ + C+ D TC L S + PC GC C QG + C
Sbjct: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 942
Query: 648 HKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFP 707
+C C + G Y G+ + + C+C+ G C C S
Sbjct: 943 EECPCTWKGKEYFPGDQVMSPCHT---CVCQRGS-FQCTLHPCAS--------------- 983
Query: 708 KRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLR 767
C ++ TFDG + F L+K+ + + I N +G +
Sbjct: 984 ----TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD-VSFSVIVENVNCYSSGMICRK 1038
Query: 768 GLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVE-SKGVVTVQ 826
+ I V + + +G F ++ +R T V + +T+
Sbjct: 1039 FISINVGNSLIVFDDD-------SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLL 1091
Query: 827 YSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICN 886
+ ++++ + GLCG ++ +E P N F SW E
Sbjct: 1092 WDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVE---- 1147
Query: 887 GECGDLLKACNNDSELLKFYR---SRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRL 943
C D L D +L R ++ C I+ + F CH VV+VT +Y CL
Sbjct: 1148 --CPDTLDP--RDMCVLNPLREPFAKKECSIL---LSEVFEICHPVVDVTWFYSNCLTDT 1200
Query: 944 --CQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLEC 984
C GG+ C SV+ YA C V V WRT CP +C
Sbjct: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 70.5 bits (171), Expect = 2e-11
Identities = 70/286 (24%), Positives = 114/286 (39%), Gaps = 30/286 (10%)
Query: 831 GLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCT---DNLAVFLESWTTFEEICN- 886
GL+ + S T GLCG + +A+++ L +G ++ A FL+SW + +
Sbjct: 2230 GLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSV 2289
Query: 887 GECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQS 946
G+ +C S C + SN +F CH V ++ + +
Sbjct: 2290 GQTRFRPDSCATTD--------CSPC--LRMVSNRTFSACHRFVPPESFCELWI----RD 2335
Query: 947 GGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECITCTE---TCETL 1003
+ C ++ Y + C V + WR D+CP C +S ++ C+T E TC+
Sbjct: 2336 TKYVQQPCVALTVYVAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG 2394
Query: 1004 TLGPICVDSC---SEGCQCDEGYAL---LGSQCVTRSECGC-NFEGHQLATNETFWVDLD 1056
LGP+ + C EGC C EG L + C+ ++C C + G A ET+ L
Sbjct: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454
Query: 1057 CQIFCYCSGTDNRVHCET-IPCKDDEYCMEEGGLYYCQARTDASCI 1101
C D V + P E C+ G + D C+
Sbjct: 2455 GCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2500
Score = 70.1 bits (170), Expect = 2e-11
Identities = 79/361 (21%), Positives = 128/361 (35%), Gaps = 49/361 (13%)
Query: 1402 CVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDP 1461
C+ GC C G + +G +C LP C C GK Y P S C C C +R QC
Sbjct: 922 CLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM-SPC-HTCVC-QRGSFQCTL 978
Query: 1462 RQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLP 1521
C S C A G +RTFDG F C L +
Sbjct: 979 HPC-------------------ASTCTAYGDRHYRTFDGLPFDFVGACKVHL---VKSTS 1016
Query: 1522 DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKI 1581
D+SF +I+ + + + + I+ +D +G F+
Sbjct: 1017 DVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDD-----SGNPSPESFLDDKQEVH 1071
Query: 1582 YSSEGFLVIDTSPD--IQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGK 1639
GF + P I + ++ + + + Q ++ GLCGNF+ ++ T
Sbjct: 1072 TWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENL 1131
Query: 1640 PVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKG 1699
+ + SW A C + + MC +++ C L +
Sbjct: 1132 ELTNPQEFGSSW---------AAVECPDTLDPR--DMCVLNPLREPFAKKECSIL--LSE 1178
Query: 1700 FFQPCYGLLDPLPFYESCYLDGCYSHKKFQ---LCGSLAAYGEACRSFGILSTEWIEKEN 1756
F+ C+ ++D FY +C D C + C S++AY C G+ + +W
Sbjct: 1179 VFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGV-AVDWRTPRL 1237
Query: 1757 C 1757
C
Sbjct: 1238 C 1238
Score = 68.2 bits (165), Expect = 8e-11
Identities = 81/368 (22%), Positives = 138/368 (37%), Gaps = 44/368 (11%)
Query: 1161 VDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYD 1220
+++T + + I R + V V+ + ++ P+ +I + ++ +D ++ ++
Sbjct: 2170 LNMTHLAHQVTIDR-FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHS 2228
Query: 1221 WKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNE---FGQSWVKRDTFC 1277
+ + ++ + +GLCG +G+ +DL + G + + F SW +
Sbjct: 2229 -SGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLT 2287
Query: 1278 QVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGA 1337
VG P S ++ S N FS CH V P F + + D+
Sbjct: 2288 SVGQTRFRPDSCATTDCSPCLRMVS-----NRTFSACHRFVPPESFCELWIRDTKY---- 2338
Query: 1338 VQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQP--RCA-AIRL 1394
VQ C L Y + C + + WR C C +S Y++CV+ C+P C I
Sbjct: 2339 VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILG 2397
Query: 1395 KSDCSHYCV--EGCHCDAGYVLNGKS---CILPHSCGCYSDGKYYEPKQLFWNSDCTRRC 1449
D H V EGC C G +L+ + CI C C WNS + C
Sbjct: 2398 PLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457
Query: 1450 RCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANC 1509
+ QC++ + + GC S + CL F L P
Sbjct: 2458 Q-----------HQCQAPDTIVPVD--LGCPSPRPESCL--------RFGEVALLLPTKD 2496
Query: 1510 AFVLSTIC 1517
L T+C
Sbjct: 2497 PCCLGTVC 2504
Score = 40.4 bits (93), Expect = 0.019
Identities = 69/305 (22%), Positives = 111/305 (36%), Gaps = 50/305 (16%)
Query: 1495 FRTFDGAFLRFPANCAFVLSTICQKLPDISF----QLIINFDKWSAPNLTIISPVYFYIN 1550
F TFDG+ + ++LS ++ + + W L +++ +
Sbjct: 2119 FVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHL--- 2175
Query: 1551 EEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYY---NGFNVIK 1607
Q+ I+ N Q P ++ +I + +I T DIQI + +G +++
Sbjct: 2176 AHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVE 2235
Query: 1608 ISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSS----VVLAQSWK-----TNGMQK 1658
S + + Q GLCG +GD +D +TL+ VV SW+ T+ Q
Sbjct: 2236 ASKTSKAQGH--GLCGICDGDAAND-LTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2292
Query: 1659 RPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCY 1718
R SC S CL++ + F C+ + P F E
Sbjct: 2293 RFRPDSCATTDCSP------------------CLRMVSNR-TFSACHRFVPPESFCELWI 2333
Query: 1719 LDGCYSHKKFQLCGSLAAYGEACRSFGILSTEWIEKENC-----SGVVEDPCVGADCPNR 1773
D Y Q C +L Y C F + EW + C S CV A P +
Sbjct: 2334 RDTKYVQ---QPCVALTVYVAMCHKFHV-CIEWRRSDYCPFLCSSDSTYQACVTACEPPK 2389
Query: 1774 TCELG 1778
TC+ G
Sbjct: 2390 TCQDG 2394
Score = 38.9 bits (89), Expect = 0.055
Identities = 60/294 (20%), Positives = 97/294 (32%), Gaps = 77/294 (26%)
Query: 459 GLCGNYNKNPLDDFLRPDGRPAMSVLDLG---ESWRVYHA-------DWKCDSGCVDNCT 508
GLCG + + +D DG D +SW+V + ++ DS +C+
Sbjct: 2246 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCS 2305
Query: 509 QCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAI 568
C F + C V P +F + D V+ C A+
Sbjct: 2306 PCLRMVSNRTFSA---------------CHRFVPPESFCELWIRDTKYVQQP----CVAL 2346
Query: 569 QAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCT 628
Y +C + I +WR + CP CS + + C T C
Sbjct: 2347 TVYVAMCHKFHVCI-EWRR-------------------SDYCPFLCSSDSTYQACVTACE 2386
Query: 629 ----------------------EGCECNQGFVL---STSQCVPLHKCGC-DFDGHYYTMG 662
EGC C++G +L ++ C+P KC C D G +G
Sbjct: 2387 PPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALG 2446
Query: 663 EFFWATANCTVQCLCEEGGDVYCFNKTCGS--GEVCAVEDGYQGCFPKRETVCL 714
E + ++ + Q C+ + + C S E C P ++ CL
Sbjct: 2447 ETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2500
>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 237 bits (605), Expect = 8e-62
Identities = 210/797 (26%), Positives = 321/797 (40%), Gaps = 105/797 (13%)
Query: 707 PKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWL 766
P+R+++C + TFDG Y + SYTL+ + I ++ P G +
Sbjct: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHND-PQCGSSPY 131
Query: 767 RGLRIL----VADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGV 822
R + V +QE+ + A EV G V+LP H G + + V +
Sbjct: 132 TCSRAVSLFFVGEQEIHL----AKEVTHGGMRVQLP--HVMGSARLQQLAGYVIVRHQSA 185
Query: 823 VTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFE 882
T+ + +YI++S T GLCG NA+ D+ +GK TD++ F+ SW E
Sbjct: 186 FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ--E 243
Query: 883 EICNGECGDLLKAC-------NNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAY 935
+ N G + N + Y +C + P F CH V+ +
Sbjct: 244 QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY---EQCEALLRP---PFDACHAYVSPLPF 297
Query: 936 YRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRT-YDFCPLECPENSH-FEEC 993
+C LCQS G+ + C ++A YA AC A + WRT C + C E + + EC
Sbjct: 298 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 357
Query: 994 IT-CTETCETLTLGPICVDS---CSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNE 1049
I C +C CVDS C +GC C G CV +EC C F G
Sbjct: 358 IACCPASCHPRA---SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGS 414
Query: 1050 TFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYL 1109
V DC C+ T + C T C A C V+G H+
Sbjct: 415 V--VKEDCNT---CTCTSGKWECSTAVC-------------------PAECSVTGDIHFT 450
Query: 1110 TFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYS 1169
TFDG + F +C IL S S F VT +N + Q V S
Sbjct: 451 TFDGRRYTFPATCQYILA------KSRSSGTFTVTLQN------APCGLNQDGACVQSVS 498
Query: 1170 IVIHRAYKHTV---------LVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYD 1220
+++H+ + V L + ++ P +I S F + V T+ G++V+YD
Sbjct: 499 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVF-LRVRTNVGVRVLYD 557
Query: 1221 WKTF-LSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQV 1279
+ L + V + T GLCG +NGN DD P+G+ S+ FG SW +
Sbjct: 558 REGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPL 617
Query: 1280 GCGDRCPSC-AKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAV 1338
G C ++ S Q CS++ + F+ C + ++P +++ C D+C G
Sbjct: 618 VSGSPLDPCDVHLQAASYSVQACSVLTGE--MFAPCSAFLSPVPYFEQCRRDACRCG--Q 673
Query: 1339 QTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDC 1398
C+ L +YA C+ G+ V +C ++C + Y CV+ C C + C
Sbjct: 674 PCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEAC 733
Query: 1399 S---------HYCVEGCHCDAGYVLNGKS--CILPHSCGCYSDGKYYEPKQLFWNSDCTR 1447
CVEGC C L+ ++ C+ + C C+ G Y P +SD
Sbjct: 734 GVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP----GDSDIPS 789
Query: 1448 --RCRCFRRNVIQCDPR 1462
C C + V+ CD R
Sbjct: 790 LGHCHC-KDGVMSCDSR 805
Score = 202 bits (513), Expect = 4e-51
Identities = 200/816 (24%), Positives = 318/816 (38%), Gaps = 78/816 (9%)
Query: 285 CLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVET-STCVVFGEPHYHTFDGFLFHFQGS 343
C + ++ C + P+ + Y + E S C +G+ H TFDG ++ G
Sbjct: 41 CFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGK 100
Query: 344 CAY-LLARQCLQTSSLPFFSVEAKNEHRRGSA-VSWVKELSVEVNGYKI--LIPKGSYGR 399
+Y L+ R + S FS++ N+ + GS+ + + +S+ G + L + ++G
Sbjct: 101 GSYTLVGRHEPEGQS---FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGG 157
Query: 400 VKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCG 459
++V LP + G+ ++ Q V + +DG I + + T G
Sbjct: 158 MRVQ-----LPHVM--GSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHG 210
Query: 460 LCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK----CDSGCVDNCTQCDAAT- 514
LCGN N +P DD + G+ V++ SW+ + S C Q + T
Sbjct: 211 LCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTM 270
Query: 515 EALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALV 574
+ +Y + C L + P C V P F SC DLC + C+A+ YA
Sbjct: 271 QGVY---EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARA 325
Query: 575 CQALGIPIGDWRTQTGCVSTVQCPSFSH-YSVCTSSCPDTCSDLTASRNCATPCTEGCEC 633
C G P+ WRTQ TV C + Y+ C + CP +C + + C +GC C
Sbjct: 326 CAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYC 384
Query: 634 NQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSG 693
G + CV +C C+F G Y G N C C G K S
Sbjct: 385 PNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCN---TCTCTSG-------KWECST 434
Query: 694 EVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEID 753
VC E C ++ + TFDG Y FP+ Y L K+ + +
Sbjct: 435 AVCPAE-------------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQ 481
Query: 754 INKKKPDAGPAWLRGLRILV-ADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYR-N 811
+ A ++ + +++ D ++ A +V L Q +P + EI R +
Sbjct: 482 NAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPY-TDDAFEIRRLS 540
Query: 812 KNSTTVESKGVVTVQYSDIGL-LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDN 870
V + V V Y GL LY+++ + T GLCG +N N D+F P G
Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
Query: 871 LAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVV 930
+F SW T G L C D L S C ++ + F C +
Sbjct: 601 PQLFGNSWKTLSACSPLVSGSPLDPC--DVHLQAASYSVQACSVL---TGEMFAPCSAFL 655
Query: 931 NVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHF 990
+ Y+ C C+ G + LC ++A YA C+ + V C L C + +
Sbjct: 656 SPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEY 713
Query: 991 EECIT-CTETCETLTLGPIC---------VDSCSEGCQC--DEGYALLGSQCVTRSECGC 1038
C+ C TC+ L C D C EGC C D CV R++C C
Sbjct: 714 SPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 773
Query: 1039 NFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCET 1074
+F+G ++ D+ C+C D + C++
Sbjct: 774 HFQGVDYPPGDS---DIPSLGHCHCK--DGVMSCDS 804
Score = 182 bits (461), Expect = 4e-45
Identities = 185/718 (25%), Positives = 268/718 (37%), Gaps = 72/718 (10%)
Query: 1089 LYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNE 1148
+Y D+ C G H TFDG + L P SF + N+
Sbjct: 68 VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR-HEPEGQSFS---IQVHND 123
Query: 1149 DRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVV 1208
+ S + F IH A + V R+ LP +G ++ +V+
Sbjct: 124 PQCGSSPYTCSRAVSLFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQ--QLAGYVI 179
Query: 1209 VETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQ 1268
V + +D + + I + + T+GLCG N +P DDL G L V EF
Sbjct: 180 VRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVH 239
Query: 1269 SWVKRDTFCQVGCGDRC---PSCAKVEG--FSKVQQLCSLIPNQNAAFSKCHSKVNPTFF 1323
SW ++ G P C + V + C + F CH+ V+P F
Sbjct: 240 SWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL--LRPPFDACHAYVSPLPF 297
Query: 1324 YKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYT-SCTVTCPPNSH-YESC 1381
+C D C G V T C L YA C G + GWR CTV C + Y C
Sbjct: 298 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 357
Query: 1382 VSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW 1441
++ C C D CV+GC+C G + C+ P C C G Y P +
Sbjct: 358 IACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVV- 416
Query: 1442 NSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGA 1501
DC C C +C C ++ C G F TFDG
Sbjct: 417 KEDCNT-CTC-TSGKWECSTAVCPAE-------------------CSVTGDIHFTTFDGR 455
Query: 1502 FLRFPANCAFVLS------TICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQIL 1555
FPA C ++L+ T L + L N D ++++I Q+
Sbjct: 456 RYTFPATCQYILAKSRSSGTFTVTLQNAPCGL--NQDGACVQSVSVI---LHQDPRRQVT 510
Query: 1556 INDRNTVKVNGTQVNVPFITGLATKIYS-SEGFLVIDTSPDIQIYYNGFNV-IKISISER 1613
+ V + +P T A +I S FL + T+ +++ Y+ + + + + +R
Sbjct: 511 LTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQR 570
Query: 1614 LQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQY 1673
GLCG FNG+ DD+++ G P + + SWKT +C+ L
Sbjct: 571 WVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT--------LSACSPLVSGSP 622
Query: 1674 AAMCDNVHIQKMQ-GDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQLCG 1732
CD VH+Q C LT F PC L P+P++E C D C + LC
Sbjct: 623 LDPCD-VHLQAASYSVQACSVLTG--EMFAPCSAFLSPVPYFEQCRRDACRCGQPC-LCA 678
Query: 1733 SLAAYGEACRSFGILSTEWIEKENCSGVVE-----DPCVGADCPNRTCELGNGRELCG 1785
+LA Y CR G+ C+ E PCV A C RTC+ E CG
Sbjct: 679 TLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV-APC-GRTCQDLASPEACG 734
Score = 134 bits (337), Expect = 1e-30
Identities = 118/453 (26%), Positives = 183/453 (40%), Gaps = 52/453 (11%)
Query: 254 IDPANGCTSRGQFLRRGEVFWDDLNCTVKCRC-LDFNNEIY---------CQEASCSPYE 303
+D C G + G +F +D C C +F+ +Y C +C+
Sbjct: 372 VDSEIACVD-GCYCPNGLIF-EDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCT--- 426
Query: 304 VCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSV 363
GK+ +AV + C V G+ H+ TFDG + F +C Y+LA+ + S F+V
Sbjct: 427 ----SGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTV 478
Query: 364 EAKNE----HRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVK 419
+N ++ G+ V V + + ++ + + G V + D +P D
Sbjct: 479 TLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA--GDVLLFDQYKIIPPYTDDAFEI 536
Query: 420 IYQSGISTAVETDFGLLVTFDGQHYAS-ISVPGSYINSTCGLCGNYNKNPLDDFLRPDGR 478
S + V T+ G+ V +D + + V ++ T GLCG +N N DDFL P G
Sbjct: 537 RRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGV 596
Query: 479 PAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECG 538
P + G SW+ A SG CD +A + C L T C
Sbjct: 597 PESTPQLFGNSWKTLSACSPLVSG--SPLDPCDVHLQAASYSVQACSVL--TGEMFAPCS 652
Query: 539 TVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCP 598
+ P + C D C R LC + YA +C+ G+P+ D+R + + + C
Sbjct: 653 AFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPV-DFRARLPACA-LSCE 708
Query: 599 SFSHYSVCTSSCPDTCSDLTASRNCAT---------PCTEGCECNQGFVLSTSQ--CVPL 647
+ YS C + C TC DL + C C EGC C L T CVP
Sbjct: 709 ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPR 768
Query: 648 HKCGCDFDGHYYTMGEFFWATANCTVQCLCEEG 680
++C C F G Y G+ + C C++G
Sbjct: 769 NQCSCHFQGVDYPPGD---SDIPSLGHCHCKDG 798
Score = 112 bits (279), Expect = 5e-24
Identities = 104/403 (25%), Positives = 158/403 (39%), Gaps = 57/403 (14%)
Query: 984 CPENSHFEEC--------ITCTETCET--LTLGPICVDSCSEGCQCDEGYALLGSQCVTR 1033
CP F C ++ TCE L L C GC C +G G C
Sbjct: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
Query: 1034 SECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQ 1093
EC C ++G + Y G C T C + G + C
Sbjct: 871 EECPCTWKGKE-----------------YFPGDQVMSPCHTCVC--------QRGSFQCT 905
Query: 1094 ARTDAS-CIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDP 1152
AS C G HY TFDG PFDF +C + L S S F V +N +
Sbjct: 906 LHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV------KSTSDVSFSVIVENVNCYS 959
Query: 1153 SLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVE-T 1211
S + K + + V G S+++ + S +L K +++ + GF +V
Sbjct: 960 SGMICRKFISINV-GNSLIV---FDDDSGNPSPESFLDDK---QEVHTWRVGFFTLVHFP 1012
Query: 1212 DFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWV 1271
+ +++D +T + + Q GLCG ++ +++ P L ++ EFG SW
Sbjct: 1013 QEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWA 1072
Query: 1272 KRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDS 1331
+ + D C E F+K + CS++ ++ F CH V+ T+FY NCL D+
Sbjct: 1073 AVECPDTLDPRDMCVLNPLREPFAKKE--CSILLSE--VFEICHPVVDVTWFYSNCLTDT 1128
Query: 1332 --CIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTC 1372
C GG + C+ + YA C G+ V WR C C
Sbjct: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 84.3 bits (207), Expect = 1e-15
Identities = 82/338 (24%), Positives = 128/338 (37%), Gaps = 27/338 (7%)
Query: 258 NGCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAV 317
+GC LR G+ + +C C E + + SP C + F C+
Sbjct: 852 SGCACPQGLLRHGDACF----LPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLH 907
Query: 318 E-TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVS 376
STC +G+ HY TFDG F F G+C L + S FSV +N + S +
Sbjct: 908 PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS----FSVIVENVNCYSSGMI 963
Query: 377 WVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVE-TDFGL 435
K +S+ V G +++ G + D V ++ G T V +
Sbjct: 964 CRKFISINV-GNSLIVFDDDSGNPSPESFLD------DKQEVHTWRVGFFTLVHFPQEHI 1016
Query: 436 LVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHA 495
+ +D + + + GLCGN++ +++ P+ + + G SW A
Sbjct: 1017 TLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW----A 1072
Query: 496 DWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLC 555
+C +D C F C L + C VVD T F +C+ D C
Sbjct: 1073 AVECPD-TLDPRDMCVLNPLREPFAKKECSILLSEVFEI--CHPVVDVTWFYSNCLTDTC 1129
Query: 556 SVRDNG--TLLCQAIQAYALVCQALGIPIGDWRTQTGC 591
G C ++ AYA C G+ + DWRT C
Sbjct: 1130 GCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLC 1166
Score = 72.4 bits (176), Expect = 4e-12
Identities = 92/403 (22%), Positives = 142/403 (35%), Gaps = 58/403 (14%)
Query: 597 CPSFSHYSVCTSSCPD-------TCSD--LTASRNCATPCTEGCECNQGFVLSTSQCVPL 647
CP+ + C+ D TC L S + PC GC C QG + C
Sbjct: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
Query: 648 HKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFP 707
+C C + G Y G+ + + C+C+ G C C S
Sbjct: 871 EECPCTWKGKEYFPGDQVMSPCHT---CVCQRGS-FQCTLHPCAS--------------- 911
Query: 708 KRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLR 767
C ++ TFDG + F L+K+ + + I N +G +
Sbjct: 912 ----TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD-VSFSVIVENVNCYSSGMICRK 966
Query: 768 GLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVE-SKGVVTVQ 826
+ I V + + +G F ++ +R T V + +T+
Sbjct: 967 FISINVGNSLIVFDDD-------SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLL 1019
Query: 827 YSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICN 886
+ ++++ + GLCG ++ +E P N F SW E
Sbjct: 1020 WDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVE---- 1075
Query: 887 GECGDLLKACNNDSELLKFYR---SRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRL 943
C D L D +L R ++ C I+ + F CH VV+VT +Y CL
Sbjct: 1076 --CPDTLDP--RDMCVLNPLREPFAKKECSIL---LSEVFEICHPVVDVTWFYSNCLTDT 1128
Query: 944 --CQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLEC 984
C GG+ C SV+ YA C V V WRT CP +C
Sbjct: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 70.5 bits (171), Expect = 2e-11
Identities = 70/286 (24%), Positives = 114/286 (39%), Gaps = 30/286 (10%)
Query: 831 GLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCT---DNLAVFLESWTTFEEICN- 886
GL+ + S T GLCG + +A+++ L +G ++ A FL+SW + +
Sbjct: 2158 GLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSV 2217
Query: 887 GECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQS 946
G+ +C S C + SN +F CH V ++ + +
Sbjct: 2218 GQTRFRPDSCATTD--------CSPC--LRMVSNRTFSACHRFVPPESFCELWI----RD 2263
Query: 947 GGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECITCTE---TCETL 1003
+ C ++ Y + C V + WR D+CP C +S ++ C+T E TC+
Sbjct: 2264 TKYVQQPCVALTVYVAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG 2322
Query: 1004 TLGPICVDSC---SEGCQCDEGYAL---LGSQCVTRSECGC-NFEGHQLATNETFWVDLD 1056
LGP+ + C EGC C EG L + C+ ++C C + G A ET+ L
Sbjct: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
Query: 1057 CQIFCYCSGTDNRVHCET-IPCKDDEYCMEEGGLYYCQARTDASCI 1101
C D V + P E C+ G + D C+
Sbjct: 2383 GCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2428
Score = 70.1 bits (170), Expect = 2e-11
Identities = 79/361 (21%), Positives = 128/361 (35%), Gaps = 49/361 (13%)
Query: 1402 CVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDP 1461
C+ GC C G + +G +C LP C C GK Y P S C C C +R QC
Sbjct: 850 CLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM-SPC-HTCVC-QRGSFQCTL 906
Query: 1462 RQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLP 1521
C S C A G +RTFDG F C L +
Sbjct: 907 HPC-------------------ASTCTAYGDRHYRTFDGLPFDFVGACKVHL---VKSTS 944
Query: 1522 DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKI 1581
D+SF +I+ + + + + I+ +D +G F+
Sbjct: 945 DVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDD-----SGNPSPESFLDDKQEVH 999
Query: 1582 YSSEGFLVIDTSPD--IQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGK 1639
GF + P I + ++ + + + Q ++ GLCGNF+ ++ T
Sbjct: 1000 TWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENL 1059
Query: 1640 PVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKG 1699
+ + SW A C + + MC +++ C L +
Sbjct: 1060 ELTNPQEFGSSW---------AAVECPDTLDPR--DMCVLNPLREPFAKKECSIL--LSE 1106
Query: 1700 FFQPCYGLLDPLPFYESCYLDGCYSHKKFQ---LCGSLAAYGEACRSFGILSTEWIEKEN 1756
F+ C+ ++D FY +C D C + C S++AY C G+ + +W
Sbjct: 1107 VFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGV-AVDWRTPRL 1165
Query: 1757 C 1757
C
Sbjct: 1166 C 1166
Score = 68.2 bits (165), Expect = 8e-11
Identities = 81/368 (22%), Positives = 138/368 (37%), Gaps = 44/368 (11%)
Query: 1161 VDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYD 1220
+++T + + I R + V V+ + ++ P+ +I + ++ +D ++ ++
Sbjct: 2098 LNMTHLAHQVTIDR-FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHS 2156
Query: 1221 WKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNE---FGQSWVKRDTFC 1277
+ + ++ + +GLCG +G+ +DL + G + + F SW +
Sbjct: 2157 -SGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLT 2215
Query: 1278 QVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGA 1337
VG P S ++ S N FS CH V P F + + D+
Sbjct: 2216 SVGQTRFRPDSCATTDCSPCLRMVS-----NRTFSACHRFVPPESFCELWIRDTKY---- 2266
Query: 1338 VQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQP--RCA-AIRL 1394
VQ C L Y + C + + WR C C +S Y++CV+ C+P C I
Sbjct: 2267 VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILG 2325
Query: 1395 KSDCSHYCV--EGCHCDAGYVLNGKS---CILPHSCGCYSDGKYYEPKQLFWNSDCTRRC 1449
D H V EGC C G +L+ + CI C C WNS + C
Sbjct: 2326 PLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
Query: 1450 RCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANC 1509
+ QC++ + + GC S + CL F L P
Sbjct: 2386 Q-----------HQCQAPDTIVPVD--LGCPSPRPESCL--------RFGEVALLLPTKD 2424
Query: 1510 AFVLSTIC 1517
L T+C
Sbjct: 2425 PCCLGTVC 2432
Score = 40.4 bits (93), Expect = 0.019
Identities = 69/305 (22%), Positives = 111/305 (36%), Gaps = 50/305 (16%)
Query: 1495 FRTFDGAFLRFPANCAFVLSTICQKLPDISF----QLIINFDKWSAPNLTIISPVYFYIN 1550
F TFDG+ + ++LS ++ + + W L +++ +
Sbjct: 2047 FVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHL--- 2103
Query: 1551 EEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYY---NGFNVIK 1607
Q+ I+ N Q P ++ +I + +I T DIQI + +G +++
Sbjct: 2104 AHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVE 2163
Query: 1608 ISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSS----VVLAQSWK-----TNGMQK 1658
S + + Q GLCG +GD +D +TL+ VV SW+ T+ Q
Sbjct: 2164 ASKTSKAQGH--GLCGICDGDAAND-LTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
Query: 1659 RPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCY 1718
R SC S CL++ + F C+ + P F E
Sbjct: 2221 RFRPDSCATTDCSP------------------CLRMVSNR-TFSACHRFVPPESFCELWI 2261
Query: 1719 LDGCYSHKKFQLCGSLAAYGEACRSFGILSTEWIEKENC-----SGVVEDPCVGADCPNR 1773
D Y Q C +L Y C F + EW + C S CV A P +
Sbjct: 2262 RDTKYVQ---QPCVALTVYVAMCHKFHV-CIEWRRSDYCPFLCSSDSTYQACVTACEPPK 2317
Query: 1774 TCELG 1778
TC+ G
Sbjct: 2318 TCQDG 2322
Score = 38.9 bits (89), Expect = 0.055
Identities = 60/294 (20%), Positives = 97/294 (32%), Gaps = 77/294 (26%)
Query: 459 GLCGNYNKNPLDDFLRPDGRPAMSVLDLG---ESWRVYHA-------DWKCDSGCVDNCT 508
GLCG + + +D DG D +SW+V + ++ DS +C+
Sbjct: 2174 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCS 2233
Query: 509 QCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAI 568
C F + C V P +F + D V+ C A+
Sbjct: 2234 PCLRMVSNRTFSA---------------CHRFVPPESFCELWIRDTKYVQQP----CVAL 2274
Query: 569 QAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCT 628
Y +C + I +WR + CP CS + + C T C
Sbjct: 2275 TVYVAMCHKFHVCI-EWRR-------------------SDYCPFLCSSDSTYQACVTACE 2314
Query: 629 ----------------------EGCECNQGFVL---STSQCVPLHKCGC-DFDGHYYTMG 662
EGC C++G +L ++ C+P KC C D G +G
Sbjct: 2315 PPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALG 2374
Query: 663 EFFWATANCTVQCLCEEGGDVYCFNKTCGS--GEVCAVEDGYQGCFPKRETVCL 714
E + ++ + Q C+ + + C S E C P ++ CL
Sbjct: 2375 ETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2428
>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 237 bits (605), Expect = 8e-62
Identities = 210/797 (26%), Positives = 321/797 (40%), Gaps = 105/797 (13%)
Query: 707 PKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWL 766
P+R+++C + TFDG Y + SYTL+ + I ++ P G +
Sbjct: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHND-PQCGSSPY 203
Query: 767 RGLRIL----VADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGV 822
R + V +QE+ + A EV G V+LP H G + + V +
Sbjct: 204 TCSRAVSLFFVGEQEIHL----AKEVTHGGMRVQLP--HVMGSARLQQLAGYVIVRHQSA 257
Query: 823 VTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFE 882
T+ + +YI++S T GLCG NA+ D+ +GK TD++ F+ SW E
Sbjct: 258 FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ--E 315
Query: 883 EICNGECGDLLKAC-------NNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAY 935
+ N G + N + Y +C + P F CH V+ +
Sbjct: 316 QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY---EQCEALLRP---PFDACHAYVSPLPF 369
Query: 936 YRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRT-YDFCPLECPENSH-FEEC 993
+C LCQS G+ + C ++A YA AC A + WRT C + C E + + EC
Sbjct: 370 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 429
Query: 994 IT-CTETCETLTLGPICVDS---CSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNE 1049
I C +C CVDS C +GC C G CV +EC C F G
Sbjct: 430 IACCPASCHPRA---SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGS 486
Query: 1050 TFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYL 1109
V DC C+ T + C T C A C V+G H+
Sbjct: 487 V--VKEDCNT---CTCTSGKWECSTAVC-------------------PAECSVTGDIHFT 522
Query: 1110 TFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYS 1169
TFDG + F +C IL S S F VT +N + Q V S
Sbjct: 523 TFDGRRYTFPATCQYILA------KSRSSGTFTVTLQN------APCGLNQDGACVQSVS 570
Query: 1170 IVIHRAYKHTV---------LVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYD 1220
+++H+ + V L + ++ P +I S F + V T+ G++V+YD
Sbjct: 571 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVF-LRVRTNVGVRVLYD 629
Query: 1221 WKTF-LSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQV 1279
+ L + V + T GLCG +NGN DD P+G+ S+ FG SW +
Sbjct: 630 REGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPL 689
Query: 1280 GCGDRCPSC-AKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAV 1338
G C ++ S Q CS++ + F+ C + ++P +++ C D+C G
Sbjct: 690 VSGSPLDPCDVHLQAASYSVQACSVLTGE--MFAPCSAFLSPVPYFEQCRRDACRCG--Q 745
Query: 1339 QTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDC 1398
C+ L +YA C+ G+ V +C ++C + Y CV+ C C + C
Sbjct: 746 PCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEAC 805
Query: 1399 S---------HYCVEGCHCDAGYVLNGKS--CILPHSCGCYSDGKYYEPKQLFWNSDCTR 1447
CVEGC C L+ ++ C+ + C C+ G Y P +SD
Sbjct: 806 GVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP----GDSDIPS 861
Query: 1448 --RCRCFRRNVIQCDPR 1462
C C + V+ CD R
Sbjct: 862 LGHCHC-KDGVMSCDSR 877
Score = 202 bits (513), Expect = 4e-51
Identities = 200/816 (24%), Positives = 318/816 (38%), Gaps = 78/816 (9%)
Query: 285 CLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVET-STCVVFGEPHYHTFDGFLFHFQGS 343
C + ++ C + P+ + Y + E S C +G+ H TFDG ++ G
Sbjct: 113 CFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGK 172
Query: 344 CAY-LLARQCLQTSSLPFFSVEAKNEHRRGSA-VSWVKELSVEVNGYKI--LIPKGSYGR 399
+Y L+ R + S FS++ N+ + GS+ + + +S+ G + L + ++G
Sbjct: 173 GSYTLVGRHEPEGQS---FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGG 229
Query: 400 VKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCG 459
++V LP + G+ ++ Q V + +DG I + + T G
Sbjct: 230 MRVQ-----LPHVM--GSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHG 282
Query: 460 LCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK----CDSGCVDNCTQCDAAT- 514
LCGN N +P DD + G+ V++ SW+ + S C Q + T
Sbjct: 283 LCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTM 342
Query: 515 EALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALV 574
+ +Y + C L + P C V P F SC DLC + C+A+ YA
Sbjct: 343 QGVY---EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARA 397
Query: 575 CQALGIPIGDWRTQTGCVSTVQCPSFSH-YSVCTSSCPDTCSDLTASRNCATPCTEGCEC 633
C G P+ WRTQ TV C + Y+ C + CP +C + + C +GC C
Sbjct: 398 CAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYC 456
Query: 634 NQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSG 693
G + CV +C C+F G Y G N C C G K S
Sbjct: 457 PNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCN---TCTCTSG-------KWECST 506
Query: 694 EVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEID 753
VC E C ++ + TFDG Y FP+ Y L K+ + +
Sbjct: 507 AVCPAE-------------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQ 553
Query: 754 INKKKPDAGPAWLRGLRILV-ADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYR-N 811
+ A ++ + +++ D ++ A +V L Q +P + EI R +
Sbjct: 554 NAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPY-TDDAFEIRRLS 612
Query: 812 KNSTTVESKGVVTVQYSDIGL-LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDN 870
V + V V Y GL LY+++ + T GLCG +N N D+F P G
Sbjct: 613 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 672
Query: 871 LAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVV 930
+F SW T G L C D L S C ++ + F C +
Sbjct: 673 PQLFGNSWKTLSACSPLVSGSPLDPC--DVHLQAASYSVQACSVL---TGEMFAPCSAFL 727
Query: 931 NVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHF 990
+ Y+ C C+ G + LC ++A YA C+ + V C L C + +
Sbjct: 728 SPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEY 785
Query: 991 EECIT-CTETCETLTLGPIC---------VDSCSEGCQC--DEGYALLGSQCVTRSECGC 1038
C+ C TC+ L C D C EGC C D CV R++C C
Sbjct: 786 SPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 845
Query: 1039 NFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCET 1074
+F+G ++ D+ C+C D + C++
Sbjct: 846 HFQGVDYPPGDS---DIPSLGHCHCK--DGVMSCDS 876
Score = 182 bits (461), Expect = 4e-45
Identities = 185/718 (25%), Positives = 268/718 (37%), Gaps = 72/718 (10%)
Query: 1089 LYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNE 1148
+Y D+ C G H TFDG + L P SF + N+
Sbjct: 140 VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR-HEPEGQSFS---IQVHND 195
Query: 1149 DRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVV 1208
+ S + F IH A + V R+ LP +G ++ +V+
Sbjct: 196 PQCGSSPYTCSRAVSLFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQ--QLAGYVI 251
Query: 1209 VETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQ 1268
V + +D + + I + + T+GLCG N +P DDL G L V EF
Sbjct: 252 VRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVH 311
Query: 1269 SWVKRDTFCQVGCGDRC---PSCAKVEG--FSKVQQLCSLIPNQNAAFSKCHSKVNPTFF 1323
SW ++ G P C + V + C + F CH+ V+P F
Sbjct: 312 SWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL--LRPPFDACHAYVSPLPF 369
Query: 1324 YKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYT-SCTVTCPPNSH-YESC 1381
+C D C G V T C L YA C G + GWR CTV C + Y C
Sbjct: 370 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 429
Query: 1382 VSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW 1441
++ C C D CV+GC+C G + C+ P C C G Y P +
Sbjct: 430 IACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVV- 488
Query: 1442 NSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGA 1501
DC C C +C C ++ C G F TFDG
Sbjct: 489 KEDCNT-CTC-TSGKWECSTAVCPAE-------------------CSVTGDIHFTTFDGR 527
Query: 1502 FLRFPANCAFVLS------TICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQIL 1555
FPA C ++L+ T L + L N D ++++I Q+
Sbjct: 528 RYTFPATCQYILAKSRSSGTFTVTLQNAPCGL--NQDGACVQSVSVI---LHQDPRRQVT 582
Query: 1556 INDRNTVKVNGTQVNVPFITGLATKIYS-SEGFLVIDTSPDIQIYYNGFNV-IKISISER 1613
+ V + +P T A +I S FL + T+ +++ Y+ + + + + +R
Sbjct: 583 LTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQR 642
Query: 1614 LQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQY 1673
GLCG FNG+ DD+++ G P + + SWKT +C+ L
Sbjct: 643 WVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT--------LSACSPLVSGSP 694
Query: 1674 AAMCDNVHIQKMQ-GDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQLCG 1732
CD VH+Q C LT F PC L P+P++E C D C + LC
Sbjct: 695 LDPCD-VHLQAASYSVQACSVLTG--EMFAPCSAFLSPVPYFEQCRRDACRCGQPC-LCA 750
Query: 1733 SLAAYGEACRSFGILSTEWIEKENCSGVVE-----DPCVGADCPNRTCELGNGRELCG 1785
+LA Y CR G+ C+ E PCV A C RTC+ E CG
Sbjct: 751 TLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV-APC-GRTCQDLASPEACG 806
Score = 134 bits (337), Expect = 1e-30
Identities = 118/453 (26%), Positives = 183/453 (40%), Gaps = 52/453 (11%)
Query: 254 IDPANGCTSRGQFLRRGEVFWDDLNCTVKCRC-LDFNNEIY---------CQEASCSPYE 303
+D C G + G +F +D C C +F+ +Y C +C+
Sbjct: 444 VDSEIACVD-GCYCPNGLIF-EDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCT--- 498
Query: 304 VCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSV 363
GK+ +AV + C V G+ H+ TFDG + F +C Y+LA+ + S F+V
Sbjct: 499 ----SGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTV 550
Query: 364 EAKNE----HRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVK 419
+N ++ G+ V V + + ++ + + G V + D +P D
Sbjct: 551 TLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA--GDVLLFDQYKIIPPYTDDAFEI 608
Query: 420 IYQSGISTAVETDFGLLVTFDGQHYAS-ISVPGSYINSTCGLCGNYNKNPLDDFLRPDGR 478
S + V T+ G+ V +D + + V ++ T GLCG +N N DDFL P G
Sbjct: 609 RRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGV 668
Query: 479 PAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECG 538
P + G SW+ A SG CD +A + C L T C
Sbjct: 669 PESTPQLFGNSWKTLSACSPLVSG--SPLDPCDVHLQAASYSVQACSVL--TGEMFAPCS 724
Query: 539 TVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCP 598
+ P + C D C R LC + YA +C+ G+P+ D+R + + + C
Sbjct: 725 AFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPV-DFRARLPACA-LSCE 780
Query: 599 SFSHYSVCTSSCPDTCSDLTASRNCAT---------PCTEGCECNQGFVLSTSQ--CVPL 647
+ YS C + C TC DL + C C EGC C L T CVP
Sbjct: 781 ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPR 840
Query: 648 HKCGCDFDGHYYTMGEFFWATANCTVQCLCEEG 680
++C C F G Y G+ + C C++G
Sbjct: 841 NQCSCHFQGVDYPPGD---SDIPSLGHCHCKDG 870
Score = 112 bits (279), Expect = 5e-24
Identities = 104/403 (25%), Positives = 158/403 (39%), Gaps = 57/403 (14%)
Query: 984 CPENSHFEEC--------ITCTETCET--LTLGPICVDSCSEGCQCDEGYALLGSQCVTR 1033
CP F C ++ TCE L L C GC C +G G C
Sbjct: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 942
Query: 1034 SECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQ 1093
EC C ++G + Y G C T C + G + C
Sbjct: 943 EECPCTWKGKE-----------------YFPGDQVMSPCHTCVC--------QRGSFQCT 977
Query: 1094 ARTDAS-CIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDP 1152
AS C G HY TFDG PFDF +C + L S S F V +N +
Sbjct: 978 LHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV------KSTSDVSFSVIVENVNCYS 1031
Query: 1153 SLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVE-T 1211
S + K + + V G S+++ + S +L K +++ + GF +V
Sbjct: 1032 SGMICRKFISINV-GNSLIV---FDDDSGNPSPESFLDDK---QEVHTWRVGFFTLVHFP 1084
Query: 1212 DFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWV 1271
+ +++D +T + + Q GLCG ++ +++ P L ++ EFG SW
Sbjct: 1085 QEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWA 1144
Query: 1272 KRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDS 1331
+ + D C E F+K + CS++ ++ F CH V+ T+FY NCL D+
Sbjct: 1145 AVECPDTLDPRDMCVLNPLREPFAKKE--CSILLSE--VFEICHPVVDVTWFYSNCLTDT 1200
Query: 1332 --CIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTC 1372
C GG + C+ + YA C G+ V WR C C
Sbjct: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 84.3 bits (207), Expect = 1e-15
Identities = 82/338 (24%), Positives = 128/338 (37%), Gaps = 27/338 (7%)
Query: 258 NGCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAV 317
+GC LR G+ + +C C E + + SP C + F C+
Sbjct: 924 SGCACPQGLLRHGDACF----LPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLH 979
Query: 318 E-TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVS 376
STC +G+ HY TFDG F F G+C L + S FSV +N + S +
Sbjct: 980 PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS----FSVIVENVNCYSSGMI 1035
Query: 377 WVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVE-TDFGL 435
K +S+ V G +++ G + D V ++ G T V +
Sbjct: 1036 CRKFISINV-GNSLIVFDDDSGNPSPESFLD------DKQEVHTWRVGFFTLVHFPQEHI 1088
Query: 436 LVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHA 495
+ +D + + + GLCGN++ +++ P+ + + G SW A
Sbjct: 1089 TLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW----A 1144
Query: 496 DWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLC 555
+C +D C F C L + C VVD T F +C+ D C
Sbjct: 1145 AVECPD-TLDPRDMCVLNPLREPFAKKECSILLSEVFEI--CHPVVDVTWFYSNCLTDTC 1201
Query: 556 SVRDNG--TLLCQAIQAYALVCQALGIPIGDWRTQTGC 591
G C ++ AYA C G+ + DWRT C
Sbjct: 1202 GCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLC 1238
Score = 72.4 bits (176), Expect = 4e-12
Identities = 92/403 (22%), Positives = 142/403 (35%), Gaps = 58/403 (14%)
Query: 597 CPSFSHYSVCTSSCPD-------TCSD--LTASRNCATPCTEGCECNQGFVLSTSQCVPL 647
CP+ + C+ D TC L S + PC GC C QG + C
Sbjct: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 942
Query: 648 HKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFP 707
+C C + G Y G+ + + C+C+ G C C S
Sbjct: 943 EECPCTWKGKEYFPGDQVMSPCHT---CVCQRGS-FQCTLHPCAS--------------- 983
Query: 708 KRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLR 767
C ++ TFDG + F L+K+ + + I N +G +
Sbjct: 984 ----TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD-VSFSVIVENVNCYSSGMICRK 1038
Query: 768 GLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVE-SKGVVTVQ 826
+ I V + + +G F ++ +R T V + +T+
Sbjct: 1039 FISINVGNSLIVFDDD-------SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLL 1091
Query: 827 YSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICN 886
+ ++++ + GLCG ++ +E P N F SW E
Sbjct: 1092 WDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVE---- 1147
Query: 887 GECGDLLKACNNDSELLKFYR---SRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRL 943
C D L D +L R ++ C I+ + F CH VV+VT +Y CL
Sbjct: 1148 --CPDTLDP--RDMCVLNPLREPFAKKECSIL---LSEVFEICHPVVDVTWFYSNCLTDT 1200
Query: 944 --CQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLEC 984
C GG+ C SV+ YA C V V WRT CP +C
Sbjct: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 70.5 bits (171), Expect = 2e-11
Identities = 70/286 (24%), Positives = 114/286 (39%), Gaps = 30/286 (10%)
Query: 831 GLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCT---DNLAVFLESWTTFEEICN- 886
GL+ + S T GLCG + +A+++ L +G ++ A FL+SW + +
Sbjct: 2230 GLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSV 2289
Query: 887 GECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQS 946
G+ +C S C + SN +F CH V ++ + +
Sbjct: 2290 GQTRFRPDSCATTD--------CSPC--LRMVSNRTFSACHRFVPPESFCELWI----RD 2335
Query: 947 GGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECITCTE---TCETL 1003
+ C ++ Y + C V + WR D+CP C +S ++ C+T E TC+
Sbjct: 2336 TKYVQQPCVALTVYVAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG 2394
Query: 1004 TLGPICVDSC---SEGCQCDEGYAL---LGSQCVTRSECGC-NFEGHQLATNETFWVDLD 1056
LGP+ + C EGC C EG L + C+ ++C C + G A ET+ L
Sbjct: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454
Query: 1057 CQIFCYCSGTDNRVHCET-IPCKDDEYCMEEGGLYYCQARTDASCI 1101
C D V + P E C+ G + D C+
Sbjct: 2455 GCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2500
Score = 70.1 bits (170), Expect = 2e-11
Identities = 79/361 (21%), Positives = 128/361 (35%), Gaps = 49/361 (13%)
Query: 1402 CVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDP 1461
C+ GC C G + +G +C LP C C GK Y P S C C C +R QC
Sbjct: 922 CLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM-SPC-HTCVC-QRGSFQCTL 978
Query: 1462 RQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLP 1521
C S C A G +RTFDG F C L +
Sbjct: 979 HPC-------------------ASTCTAYGDRHYRTFDGLPFDFVGACKVHL---VKSTS 1016
Query: 1522 DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKI 1581
D+SF +I+ + + + + I+ +D +G F+
Sbjct: 1017 DVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDD-----SGNPSPESFLDDKQEVH 1071
Query: 1582 YSSEGFLVIDTSPD--IQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGK 1639
GF + P I + ++ + + + Q ++ GLCGNF+ ++ T
Sbjct: 1072 TWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENL 1131
Query: 1640 PVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKG 1699
+ + SW A C + + MC +++ C L +
Sbjct: 1132 ELTNPQEFGSSW---------AAVECPDTLDPR--DMCVLNPLREPFAKKECSIL--LSE 1178
Query: 1700 FFQPCYGLLDPLPFYESCYLDGCYSHKKFQ---LCGSLAAYGEACRSFGILSTEWIEKEN 1756
F+ C+ ++D FY +C D C + C S++AY C G+ + +W
Sbjct: 1179 VFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGV-AVDWRTPRL 1237
Query: 1757 C 1757
C
Sbjct: 1238 C 1238
Score = 68.2 bits (165), Expect = 8e-11
Identities = 81/368 (22%), Positives = 138/368 (37%), Gaps = 44/368 (11%)
Query: 1161 VDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYD 1220
+++T + + I R + V V+ + ++ P+ +I + ++ +D ++ ++
Sbjct: 2170 LNMTHLAHQVTIDR-FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHS 2228
Query: 1221 WKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNE---FGQSWVKRDTFC 1277
+ + ++ + +GLCG +G+ +DL + G + + F SW +
Sbjct: 2229 -SGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLT 2287
Query: 1278 QVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGA 1337
VG P S ++ S N FS CH V P F + + D+
Sbjct: 2288 SVGQTRFRPDSCATTDCSPCLRMVS-----NRTFSACHRFVPPESFCELWIRDTKY---- 2338
Query: 1338 VQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQP--RCA-AIRL 1394
VQ C L Y + C + + WR C C +S Y++CV+ C+P C I
Sbjct: 2339 VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILG 2397
Query: 1395 KSDCSHYCV--EGCHCDAGYVLNGKS---CILPHSCGCYSDGKYYEPKQLFWNSDCTRRC 1449
D H V EGC C G +L+ + CI C C WNS + C
Sbjct: 2398 PLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457
Query: 1450 RCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANC 1509
+ QC++ + + GC S + CL F L P
Sbjct: 2458 Q-----------HQCQAPDTIVPVD--LGCPSPRPESCL--------RFGEVALLLPTKD 2496
Query: 1510 AFVLSTIC 1517
L T+C
Sbjct: 2497 PCCLGTVC 2504
Score = 40.4 bits (93), Expect = 0.019
Identities = 69/305 (22%), Positives = 111/305 (36%), Gaps = 50/305 (16%)
Query: 1495 FRTFDGAFLRFPANCAFVLSTICQKLPDISF----QLIINFDKWSAPNLTIISPVYFYIN 1550
F TFDG+ + ++LS ++ + + W L +++ +
Sbjct: 2119 FVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHL--- 2175
Query: 1551 EEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYY---NGFNVIK 1607
Q+ I+ N Q P ++ +I + +I T DIQI + +G +++
Sbjct: 2176 AHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVE 2235
Query: 1608 ISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSS----VVLAQSWK-----TNGMQK 1658
S + + Q GLCG +GD +D +TL+ VV SW+ T+ Q
Sbjct: 2236 ASKTSKAQGH--GLCGICDGDAAND-LTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2292
Query: 1659 RPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCY 1718
R SC S CL++ + F C+ + P F E
Sbjct: 2293 RFRPDSCATTDCSP------------------CLRMVSNR-TFSACHRFVPPESFCELWI 2333
Query: 1719 LDGCYSHKKFQLCGSLAAYGEACRSFGILSTEWIEKENC-----SGVVEDPCVGADCPNR 1773
D Y Q C +L Y C F + EW + C S CV A P +
Sbjct: 2334 RDTKYVQ---QPCVALTVYVAMCHKFHV-CIEWRRSDYCPFLCSSDSTYQACVTACEPPK 2389
Query: 1774 TCELG 1778
TC+ G
Sbjct: 2390 TCQDG 2394
Score = 38.9 bits (89), Expect = 0.055
Identities = 60/294 (20%), Positives = 97/294 (32%), Gaps = 77/294 (26%)
Query: 459 GLCGNYNKNPLDDFLRPDGRPAMSVLDLG---ESWRVYHA-------DWKCDSGCVDNCT 508
GLCG + + +D DG D +SW+V + ++ DS +C+
Sbjct: 2246 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCS 2305
Query: 509 QCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAI 568
C F + C V P +F + D V+ C A+
Sbjct: 2306 PCLRMVSNRTFSA---------------CHRFVPPESFCELWIRDTKYVQQP----CVAL 2346
Query: 569 QAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCT 628
Y +C + I +WR + CP CS + + C T C
Sbjct: 2347 TVYVAMCHKFHVCI-EWRR-------------------SDYCPFLCSSDSTYQACVTACE 2386
Query: 629 ----------------------EGCECNQGFVL---STSQCVPLHKCGC-DFDGHYYTMG 662
EGC C++G +L ++ C+P KC C D G +G
Sbjct: 2387 PPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALG 2446
Query: 663 EFFWATANCTVQCLCEEGGDVYCFNKTCGS--GEVCAVEDGYQGCFPKRETVCL 714
E + ++ + Q C+ + + C S E C P ++ CL
Sbjct: 2447 ETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2500
>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 237 bits (605), Expect = 8e-62
Identities = 210/797 (26%), Positives = 321/797 (40%), Gaps = 105/797 (13%)
Query: 707 PKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWL 766
P+R+++C + TFDG Y + SYTL+ + I ++ P G +
Sbjct: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHND-PQCGSSPY 131
Query: 767 RGLRIL----VADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGV 822
R + V +QE+ + A EV G V+LP H G + + V +
Sbjct: 132 TCSRAVSLFFVGEQEIHL----AKEVTHGGMRVQLP--HVMGSARLQQLAGYVIVRHQSA 185
Query: 823 VTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFE 882
T+ + +YI++S T GLCG NA+ D+ +GK TD++ F+ SW E
Sbjct: 186 FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ--E 243
Query: 883 EICNGECGDLLKAC-------NNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAY 935
+ N G + N + Y +C + P F CH V+ +
Sbjct: 244 QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY---EQCEALLRP---PFDACHAYVSPLPF 297
Query: 936 YRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRT-YDFCPLECPENSH-FEEC 993
+C LCQS G+ + C ++A YA AC A + WRT C + C E + + EC
Sbjct: 298 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 357
Query: 994 IT-CTETCETLTLGPICVDS---CSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNE 1049
I C +C CVDS C +GC C G CV +EC C F G
Sbjct: 358 IACCPASCHPRA---SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGS 414
Query: 1050 TFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYL 1109
V DC C+ T + C T C A C V+G H+
Sbjct: 415 V--VKEDCNT---CTCTSGKWECSTAVC-------------------PAECSVTGDIHFT 450
Query: 1110 TFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYS 1169
TFDG + F +C IL S S F VT +N + Q V S
Sbjct: 451 TFDGRRYTFPATCQYILA------KSRSSGTFTVTLQN------APCGLNQDGACVQSVS 498
Query: 1170 IVIHRAYKHTV---------LVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYD 1220
+++H+ + V L + ++ P +I S F + V T+ G++V+YD
Sbjct: 499 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVF-LRVRTNVGVRVLYD 557
Query: 1221 WKTF-LSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQV 1279
+ L + V + T GLCG +NGN DD P+G+ S+ FG SW +
Sbjct: 558 REGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPL 617
Query: 1280 GCGDRCPSC-AKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAV 1338
G C ++ S Q CS++ + F+ C + ++P +++ C D+C G
Sbjct: 618 VSGSPLDPCDVHLQAASYSVQACSVLTGE--MFAPCSAFLSPVPYFEQCRRDACRCG--Q 673
Query: 1339 QTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDC 1398
C+ L +YA C+ G+ V +C ++C + Y CV+ C C + C
Sbjct: 674 PCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEAC 733
Query: 1399 S---------HYCVEGCHCDAGYVLNGKS--CILPHSCGCYSDGKYYEPKQLFWNSDCTR 1447
CVEGC C L+ ++ C+ + C C+ G Y P +SD
Sbjct: 734 GVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP----GDSDIPS 789
Query: 1448 --RCRCFRRNVIQCDPR 1462
C C + V+ CD R
Sbjct: 790 LGHCHC-KDGVMSCDSR 805
Score = 202 bits (513), Expect = 4e-51
Identities = 200/816 (24%), Positives = 318/816 (38%), Gaps = 78/816 (9%)
Query: 285 CLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVET-STCVVFGEPHYHTFDGFLFHFQGS 343
C + ++ C + P+ + Y + E S C +G+ H TFDG ++ G
Sbjct: 41 CFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGK 100
Query: 344 CAY-LLARQCLQTSSLPFFSVEAKNEHRRGSA-VSWVKELSVEVNGYKI--LIPKGSYGR 399
+Y L+ R + S FS++ N+ + GS+ + + +S+ G + L + ++G
Sbjct: 101 GSYTLVGRHEPEGQS---FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGG 157
Query: 400 VKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCG 459
++V LP + G+ ++ Q V + +DG I + + T G
Sbjct: 158 MRVQ-----LPHVM--GSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHG 210
Query: 460 LCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK----CDSGCVDNCTQCDAAT- 514
LCGN N +P DD + G+ V++ SW+ + S C Q + T
Sbjct: 211 LCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTM 270
Query: 515 EALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALV 574
+ +Y + C L + P C V P F SC DLC + C+A+ YA
Sbjct: 271 QGVY---EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARA 325
Query: 575 CQALGIPIGDWRTQTGCVSTVQCPSFSH-YSVCTSSCPDTCSDLTASRNCATPCTEGCEC 633
C G P+ WRTQ TV C + Y+ C + CP +C + + C +GC C
Sbjct: 326 CAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYC 384
Query: 634 NQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSG 693
G + CV +C C+F G Y G N C C G K S
Sbjct: 385 PNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCN---TCTCTSG-------KWECST 434
Query: 694 EVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEID 753
VC E C ++ + TFDG Y FP+ Y L K+ + +
Sbjct: 435 AVCPAE-------------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQ 481
Query: 754 INKKKPDAGPAWLRGLRILV-ADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYR-N 811
+ A ++ + +++ D ++ A +V L Q +P + EI R +
Sbjct: 482 NAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPY-TDDAFEIRRLS 540
Query: 812 KNSTTVESKGVVTVQYSDIGL-LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDN 870
V + V V Y GL LY+++ + T GLCG +N N D+F P G
Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
Query: 871 LAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVV 930
+F SW T G L C D L S C ++ + F C +
Sbjct: 601 PQLFGNSWKTLSACSPLVSGSPLDPC--DVHLQAASYSVQACSVL---TGEMFAPCSAFL 655
Query: 931 NVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHF 990
+ Y+ C C+ G + LC ++A YA C+ + V C L C + +
Sbjct: 656 SPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEY 713
Query: 991 EECIT-CTETCETLTLGPIC---------VDSCSEGCQC--DEGYALLGSQCVTRSECGC 1038
C+ C TC+ L C D C EGC C D CV R++C C
Sbjct: 714 SPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 773
Query: 1039 NFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCET 1074
+F+G ++ D+ C+C D + C++
Sbjct: 774 HFQGVDYPPGDS---DIPSLGHCHCK--DGVMSCDS 804
Score = 182 bits (461), Expect = 4e-45
Identities = 185/718 (25%), Positives = 268/718 (37%), Gaps = 72/718 (10%)
Query: 1089 LYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNE 1148
+Y D+ C G H TFDG + L P SF + N+
Sbjct: 68 VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR-HEPEGQSFS---IQVHND 123
Query: 1149 DRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVV 1208
+ S + F IH A + V R+ LP +G ++ +V+
Sbjct: 124 PQCGSSPYTCSRAVSLFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQ--QLAGYVI 179
Query: 1209 VETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQ 1268
V + +D + + I + + T+GLCG N +P DDL G L V EF
Sbjct: 180 VRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVH 239
Query: 1269 SWVKRDTFCQVGCGDRC---PSCAKVEG--FSKVQQLCSLIPNQNAAFSKCHSKVNPTFF 1323
SW ++ G P C + V + C + F CH+ V+P F
Sbjct: 240 SWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL--LRPPFDACHAYVSPLPF 297
Query: 1324 YKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYT-SCTVTCPPNSH-YESC 1381
+C D C G V T C L YA C G + GWR CTV C + Y C
Sbjct: 298 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 357
Query: 1382 VSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW 1441
++ C C D CV+GC+C G + C+ P C C G Y P +
Sbjct: 358 IACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVV- 416
Query: 1442 NSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGA 1501
DC C C +C C ++ C G F TFDG
Sbjct: 417 KEDCNT-CTC-TSGKWECSTAVCPAE-------------------CSVTGDIHFTTFDGR 455
Query: 1502 FLRFPANCAFVLS------TICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQIL 1555
FPA C ++L+ T L + L N D ++++I Q+
Sbjct: 456 RYTFPATCQYILAKSRSSGTFTVTLQNAPCGL--NQDGACVQSVSVI---LHQDPRRQVT 510
Query: 1556 INDRNTVKVNGTQVNVPFITGLATKIYS-SEGFLVIDTSPDIQIYYNGFNV-IKISISER 1613
+ V + +P T A +I S FL + T+ +++ Y+ + + + + +R
Sbjct: 511 LTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQR 570
Query: 1614 LQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQY 1673
GLCG FNG+ DD+++ G P + + SWKT +C+ L
Sbjct: 571 WVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT--------LSACSPLVSGSP 622
Query: 1674 AAMCDNVHIQKMQ-GDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQLCG 1732
CD VH+Q C LT F PC L P+P++E C D C + LC
Sbjct: 623 LDPCD-VHLQAASYSVQACSVLTG--EMFAPCSAFLSPVPYFEQCRRDACRCGQPC-LCA 678
Query: 1733 SLAAYGEACRSFGILSTEWIEKENCSGVVE-----DPCVGADCPNRTCELGNGRELCG 1785
+LA Y CR G+ C+ E PCV A C RTC+ E CG
Sbjct: 679 TLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV-APC-GRTCQDLASPEACG 734
Score = 134 bits (337), Expect = 1e-30
Identities = 118/453 (26%), Positives = 183/453 (40%), Gaps = 52/453 (11%)
Query: 254 IDPANGCTSRGQFLRRGEVFWDDLNCTVKCRC-LDFNNEIY---------CQEASCSPYE 303
+D C G + G +F +D C C +F+ +Y C +C+
Sbjct: 372 VDSEIACVD-GCYCPNGLIF-EDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCT--- 426
Query: 304 VCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSV 363
GK+ +AV + C V G+ H+ TFDG + F +C Y+LA+ + S F+V
Sbjct: 427 ----SGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTV 478
Query: 364 EAKNE----HRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVK 419
+N ++ G+ V V + + ++ + + G V + D +P D
Sbjct: 479 TLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA--GDVLLFDQYKIIPPYTDDAFEI 536
Query: 420 IYQSGISTAVETDFGLLVTFDGQHYAS-ISVPGSYINSTCGLCGNYNKNPLDDFLRPDGR 478
S + V T+ G+ V +D + + V ++ T GLCG +N N DDFL P G
Sbjct: 537 RRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGV 596
Query: 479 PAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECG 538
P + G SW+ A SG CD +A + C L T C
Sbjct: 597 PESTPQLFGNSWKTLSACSPLVSG--SPLDPCDVHLQAASYSVQACSVL--TGEMFAPCS 652
Query: 539 TVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCP 598
+ P + C D C R LC + YA +C+ G+P+ D+R + + + C
Sbjct: 653 AFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPV-DFRARLPACA-LSCE 708
Query: 599 SFSHYSVCTSSCPDTCSDLTASRNCAT---------PCTEGCECNQGFVLSTSQ--CVPL 647
+ YS C + C TC DL + C C EGC C L T CVP
Sbjct: 709 ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPR 768
Query: 648 HKCGCDFDGHYYTMGEFFWATANCTVQCLCEEG 680
++C C F G Y G+ + C C++G
Sbjct: 769 NQCSCHFQGVDYPPGD---SDIPSLGHCHCKDG 798
Score = 112 bits (279), Expect = 5e-24
Identities = 104/403 (25%), Positives = 158/403 (39%), Gaps = 57/403 (14%)
Query: 984 CPENSHFEEC--------ITCTETCET--LTLGPICVDSCSEGCQCDEGYALLGSQCVTR 1033
CP F C ++ TCE L L C GC C +G G C
Sbjct: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
Query: 1034 SECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQ 1093
EC C ++G + Y G C T C + G + C
Sbjct: 871 EECPCTWKGKE-----------------YFPGDQVMSPCHTCVC--------QRGSFQCT 905
Query: 1094 ARTDAS-CIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDP 1152
AS C G HY TFDG PFDF +C + L S S F V +N +
Sbjct: 906 LHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV------KSTSDVSFSVIVENVNCYS 959
Query: 1153 SLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVE-T 1211
S + K + + V G S+++ + S +L K +++ + GF +V
Sbjct: 960 SGMICRKFISINV-GNSLIV---FDDDSGNPSPESFLDDK---QEVHTWRVGFFTLVHFP 1012
Query: 1212 DFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWV 1271
+ +++D +T + + Q GLCG ++ +++ P L ++ EFG SW
Sbjct: 1013 QEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWA 1072
Query: 1272 KRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDS 1331
+ + D C E F+K + CS++ ++ F CH V+ T+FY NCL D+
Sbjct: 1073 AVECPDTLDPRDMCVLNPLREPFAKKE--CSILLSE--VFEICHPVVDVTWFYSNCLTDT 1128
Query: 1332 --CIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTC 1372
C GG + C+ + YA C G+ V WR C C
Sbjct: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 84.3 bits (207), Expect = 1e-15
Identities = 82/338 (24%), Positives = 128/338 (37%), Gaps = 27/338 (7%)
Query: 258 NGCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAV 317
+GC LR G+ + +C C E + + SP C + F C+
Sbjct: 852 SGCACPQGLLRHGDACF----LPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLH 907
Query: 318 E-TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVS 376
STC +G+ HY TFDG F F G+C L + S FSV +N + S +
Sbjct: 908 PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS----FSVIVENVNCYSSGMI 963
Query: 377 WVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVE-TDFGL 435
K +S+ V G +++ G + D V ++ G T V +
Sbjct: 964 CRKFISINV-GNSLIVFDDDSGNPSPESFLD------DKQEVHTWRVGFFTLVHFPQEHI 1016
Query: 436 LVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHA 495
+ +D + + + GLCGN++ +++ P+ + + G SW A
Sbjct: 1017 TLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW----A 1072
Query: 496 DWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLC 555
+C +D C F C L + C VVD T F +C+ D C
Sbjct: 1073 AVECPD-TLDPRDMCVLNPLREPFAKKECSILLSEVFEI--CHPVVDVTWFYSNCLTDTC 1129
Query: 556 SVRDNG--TLLCQAIQAYALVCQALGIPIGDWRTQTGC 591
G C ++ AYA C G+ + DWRT C
Sbjct: 1130 GCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLC 1166
Score = 72.4 bits (176), Expect = 4e-12
Identities = 92/403 (22%), Positives = 142/403 (35%), Gaps = 58/403 (14%)
Query: 597 CPSFSHYSVCTSSCPD-------TCSD--LTASRNCATPCTEGCECNQGFVLSTSQCVPL 647
CP+ + C+ D TC L S + PC GC C QG + C
Sbjct: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
Query: 648 HKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFP 707
+C C + G Y G+ + + C+C+ G C C S
Sbjct: 871 EECPCTWKGKEYFPGDQVMSPCHT---CVCQRGS-FQCTLHPCAS--------------- 911
Query: 708 KRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLR 767
C ++ TFDG + F L+K+ + + I N +G +
Sbjct: 912 ----TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD-VSFSVIVENVNCYSSGMICRK 966
Query: 768 GLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVE-SKGVVTVQ 826
+ I V + + +G F ++ +R T V + +T+
Sbjct: 967 FISINVGNSLIVFDDD-------SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLL 1019
Query: 827 YSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICN 886
+ ++++ + GLCG ++ +E P N F SW E
Sbjct: 1020 WDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVE---- 1075
Query: 887 GECGDLLKACNNDSELLKFYR---SRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRL 943
C D L D +L R ++ C I+ + F CH VV+VT +Y CL
Sbjct: 1076 --CPDTLDP--RDMCVLNPLREPFAKKECSIL---LSEVFEICHPVVDVTWFYSNCLTDT 1128
Query: 944 --CQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLEC 984
C GG+ C SV+ YA C V V WRT CP +C
Sbjct: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 70.5 bits (171), Expect = 2e-11
Identities = 70/286 (24%), Positives = 114/286 (39%), Gaps = 30/286 (10%)
Query: 831 GLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCT---DNLAVFLESWTTFEEICN- 886
GL+ + S T GLCG + +A+++ L +G ++ A FL+SW + +
Sbjct: 2158 GLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSV 2217
Query: 887 GECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQS 946
G+ +C S C + SN +F CH V ++ + +
Sbjct: 2218 GQTRFRPDSCATTD--------CSPC--LRMVSNRTFSACHRFVPPESFCELWI----RD 2263
Query: 947 GGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECITCTE---TCETL 1003
+ C ++ Y + C V + WR D+CP C +S ++ C+T E TC+
Sbjct: 2264 TKYVQQPCVALTVYVAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG 2322
Query: 1004 TLGPICVDSC---SEGCQCDEGYAL---LGSQCVTRSECGC-NFEGHQLATNETFWVDLD 1056
LGP+ + C EGC C EG L + C+ ++C C + G A ET+ L
Sbjct: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
Query: 1057 CQIFCYCSGTDNRVHCET-IPCKDDEYCMEEGGLYYCQARTDASCI 1101
C D V + P E C+ G + D C+
Sbjct: 2383 GCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2428
Score = 70.1 bits (170), Expect = 2e-11
Identities = 79/361 (21%), Positives = 128/361 (35%), Gaps = 49/361 (13%)
Query: 1402 CVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDP 1461
C+ GC C G + +G +C LP C C GK Y P S C C C +R QC
Sbjct: 850 CLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM-SPC-HTCVC-QRGSFQCTL 906
Query: 1462 RQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLP 1521
C S C A G +RTFDG F C L +
Sbjct: 907 HPC-------------------ASTCTAYGDRHYRTFDGLPFDFVGACKVHL---VKSTS 944
Query: 1522 DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKI 1581
D+SF +I+ + + + + I+ +D +G F+
Sbjct: 945 DVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDD-----SGNPSPESFLDDKQEVH 999
Query: 1582 YSSEGFLVIDTSPD--IQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGK 1639
GF + P I + ++ + + + Q ++ GLCGNF+ ++ T
Sbjct: 1000 TWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENL 1059
Query: 1640 PVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKG 1699
+ + SW A C + + MC +++ C L +
Sbjct: 1060 ELTNPQEFGSSW---------AAVECPDTLDPR--DMCVLNPLREPFAKKECSIL--LSE 1106
Query: 1700 FFQPCYGLLDPLPFYESCYLDGCYSHKKFQ---LCGSLAAYGEACRSFGILSTEWIEKEN 1756
F+ C+ ++D FY +C D C + C S++AY C G+ + +W
Sbjct: 1107 VFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGV-AVDWRTPRL 1165
Query: 1757 C 1757
C
Sbjct: 1166 C 1166
Score = 68.2 bits (165), Expect = 8e-11
Identities = 81/368 (22%), Positives = 138/368 (37%), Gaps = 44/368 (11%)
Query: 1161 VDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYD 1220
+++T + + I R + V V+ + ++ P+ +I + ++ +D ++ ++
Sbjct: 2098 LNMTHLAHQVTIDR-FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHS 2156
Query: 1221 WKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNE---FGQSWVKRDTFC 1277
+ + ++ + +GLCG +G+ +DL + G + + F SW +
Sbjct: 2157 -SGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLT 2215
Query: 1278 QVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGA 1337
VG P S ++ S N FS CH V P F + + D+
Sbjct: 2216 SVGQTRFRPDSCATTDCSPCLRMVS-----NRTFSACHRFVPPESFCELWIRDTKY---- 2266
Query: 1338 VQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQP--RCA-AIRL 1394
VQ C L Y + C + + WR C C +S Y++CV+ C+P C I
Sbjct: 2267 VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILG 2325
Query: 1395 KSDCSHYCV--EGCHCDAGYVLNGKS---CILPHSCGCYSDGKYYEPKQLFWNSDCTRRC 1449
D H V EGC C G +L+ + CI C C WNS + C
Sbjct: 2326 PLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
Query: 1450 RCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANC 1509
+ QC++ + + GC S + CL F L P
Sbjct: 2386 Q-----------HQCQAPDTIVPVD--LGCPSPRPESCL--------RFGEVALLLPTKD 2424
Query: 1510 AFVLSTIC 1517
L T+C
Sbjct: 2425 PCCLGTVC 2432
Score = 40.4 bits (93), Expect = 0.019
Identities = 69/305 (22%), Positives = 111/305 (36%), Gaps = 50/305 (16%)
Query: 1495 FRTFDGAFLRFPANCAFVLSTICQKLPDISF----QLIINFDKWSAPNLTIISPVYFYIN 1550
F TFDG+ + ++LS ++ + + W L +++ +
Sbjct: 2047 FVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHL--- 2103
Query: 1551 EEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYY---NGFNVIK 1607
Q+ I+ N Q P ++ +I + +I T DIQI + +G +++
Sbjct: 2104 AHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVE 2163
Query: 1608 ISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSS----VVLAQSWK-----TNGMQK 1658
S + + Q GLCG +GD +D +TL+ VV SW+ T+ Q
Sbjct: 2164 ASKTSKAQGH--GLCGICDGDAAND-LTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
Query: 1659 RPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCY 1718
R SC S CL++ + F C+ + P F E
Sbjct: 2221 RFRPDSCATTDCSP------------------CLRMVSNR-TFSACHRFVPPESFCELWI 2261
Query: 1719 LDGCYSHKKFQLCGSLAAYGEACRSFGILSTEWIEKENC-----SGVVEDPCVGADCPNR 1773
D Y Q C +L Y C F + EW + C S CV A P +
Sbjct: 2262 RDTKYVQ---QPCVALTVYVAMCHKFHV-CIEWRRSDYCPFLCSSDSTYQACVTACEPPK 2317
Query: 1774 TCELG 1778
TC+ G
Sbjct: 2318 TCQDG 2322
Score = 38.9 bits (89), Expect = 0.055
Identities = 60/294 (20%), Positives = 97/294 (32%), Gaps = 77/294 (26%)
Query: 459 GLCGNYNKNPLDDFLRPDGRPAMSVLDLG---ESWRVYHA-------DWKCDSGCVDNCT 508
GLCG + + +D DG D +SW+V + ++ DS +C+
Sbjct: 2174 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCS 2233
Query: 509 QCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAI 568
C F + C V P +F + D V+ C A+
Sbjct: 2234 PCLRMVSNRTFSA---------------CHRFVPPESFCELWIRDTKYVQQP----CVAL 2274
Query: 569 QAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCT 628
Y +C + I +WR + CP CS + + C T C
Sbjct: 2275 TVYVAMCHKFHVCI-EWRR-------------------SDYCPFLCSSDSTYQACVTACE 2314
Query: 629 ----------------------EGCECNQGFVL---STSQCVPLHKCGC-DFDGHYYTMG 662
EGC C++G +L ++ C+P KC C D G +G
Sbjct: 2315 PPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALG 2374
Query: 663 EFFWATANCTVQCLCEEGGDVYCFNKTCGS--GEVCAVEDGYQGCFPKRETVCL 714
E + ++ + Q C+ + + C S E C P ++ CL
Sbjct: 2375 ETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2428
>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 237 bits (605), Expect = 8e-62
Identities = 210/797 (26%), Positives = 321/797 (40%), Gaps = 105/797 (13%)
Query: 707 PKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWL 766
P+R+++C + TFDG Y + SYTL+ + I ++ P G +
Sbjct: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHND-PQCGSSPY 203
Query: 767 RGLRIL----VADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGV 822
R + V +QE+ + A EV G V+LP H G + + V +
Sbjct: 204 TCSRAVSLFFVGEQEIHL----AKEVTHGGMRVQLP--HVMGSARLQQLAGYVIVRHQSA 257
Query: 823 VTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFE 882
T+ + +YI++S T GLCG NA+ D+ +GK TD++ F+ SW E
Sbjct: 258 FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ--E 315
Query: 883 EICNGECGDLLKAC-------NNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAY 935
+ N G + N + Y +C + P F CH V+ +
Sbjct: 316 QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY---EQCEALLRP---PFDACHAYVSPLPF 369
Query: 936 YRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRT-YDFCPLECPENSH-FEEC 993
+C LCQS G+ + C ++A YA AC A + WRT C + C E + + EC
Sbjct: 370 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 429
Query: 994 IT-CTETCETLTLGPICVDS---CSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNE 1049
I C +C CVDS C +GC C G CV +EC C F G
Sbjct: 430 IACCPASCHPRA---SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGS 486
Query: 1050 TFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYL 1109
V DC C+ T + C T C A C V+G H+
Sbjct: 487 V--VKEDCNT---CTCTSGKWECSTAVC-------------------PAECSVTGDIHFT 522
Query: 1110 TFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYS 1169
TFDG + F +C IL S S F VT +N + Q V S
Sbjct: 523 TFDGRRYTFPATCQYILA------KSRSSGTFTVTLQN------APCGLNQDGACVQSVS 570
Query: 1170 IVIHRAYKHTV---------LVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYD 1220
+++H+ + V L + ++ P +I S F + V T+ G++V+YD
Sbjct: 571 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVF-LRVRTNVGVRVLYD 629
Query: 1221 WKTF-LSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQV 1279
+ L + V + T GLCG +NGN DD P+G+ S+ FG SW +
Sbjct: 630 REGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPL 689
Query: 1280 GCGDRCPSC-AKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAV 1338
G C ++ S Q CS++ + F+ C + ++P +++ C D+C G
Sbjct: 690 VSGSPLDPCDVHLQAASYSVQACSVLTGE--MFAPCSAFLSPVPYFEQCRRDACRCG--Q 745
Query: 1339 QTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDC 1398
C+ L +YA C+ G+ V +C ++C + Y CV+ C C + C
Sbjct: 746 PCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEAC 805
Query: 1399 S---------HYCVEGCHCDAGYVLNGKS--CILPHSCGCYSDGKYYEPKQLFWNSDCTR 1447
CVEGC C L+ ++ C+ + C C+ G Y P +SD
Sbjct: 806 GVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP----GDSDIPS 861
Query: 1448 --RCRCFRRNVIQCDPR 1462
C C + V+ CD R
Sbjct: 862 LGHCHC-KDGVMSCDSR 877
Score = 202 bits (513), Expect = 4e-51
Identities = 200/816 (24%), Positives = 318/816 (38%), Gaps = 78/816 (9%)
Query: 285 CLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVET-STCVVFGEPHYHTFDGFLFHFQGS 343
C + ++ C + P+ + Y + E S C +G+ H TFDG ++ G
Sbjct: 113 CFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGK 172
Query: 344 CAY-LLARQCLQTSSLPFFSVEAKNEHRRGSA-VSWVKELSVEVNGYKI--LIPKGSYGR 399
+Y L+ R + S FS++ N+ + GS+ + + +S+ G + L + ++G
Sbjct: 173 GSYTLVGRHEPEGQS---FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGG 229
Query: 400 VKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCG 459
++V LP + G+ ++ Q V + +DG I + + T G
Sbjct: 230 MRVQ-----LPHVM--GSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHG 282
Query: 460 LCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK----CDSGCVDNCTQCDAAT- 514
LCGN N +P DD + G+ V++ SW+ + S C Q + T
Sbjct: 283 LCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTM 342
Query: 515 EALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALV 574
+ +Y + C L + P C V P F SC DLC + C+A+ YA
Sbjct: 343 QGVY---EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARA 397
Query: 575 CQALGIPIGDWRTQTGCVSTVQCPSFSH-YSVCTSSCPDTCSDLTASRNCATPCTEGCEC 633
C G P+ WRTQ TV C + Y+ C + CP +C + + C +GC C
Sbjct: 398 CAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYC 456
Query: 634 NQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSG 693
G + CV +C C+F G Y G N C C G K S
Sbjct: 457 PNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCN---TCTCTSG-------KWECST 506
Query: 694 EVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEID 753
VC E C ++ + TFDG Y FP+ Y L K+ + +
Sbjct: 507 AVCPAE-------------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQ 553
Query: 754 INKKKPDAGPAWLRGLRILV-ADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYR-N 811
+ A ++ + +++ D ++ A +V L Q +P + EI R +
Sbjct: 554 NAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPY-TDDAFEIRRLS 612
Query: 812 KNSTTVESKGVVTVQYSDIGL-LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDN 870
V + V V Y GL LY+++ + T GLCG +N N D+F P G
Sbjct: 613 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 672
Query: 871 LAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVV 930
+F SW T G L C D L S C ++ + F C +
Sbjct: 673 PQLFGNSWKTLSACSPLVSGSPLDPC--DVHLQAASYSVQACSVL---TGEMFAPCSAFL 727
Query: 931 NVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHF 990
+ Y+ C C+ G + LC ++A YA C+ + V C L C + +
Sbjct: 728 SPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEY 785
Query: 991 EECIT-CTETCETLTLGPIC---------VDSCSEGCQC--DEGYALLGSQCVTRSECGC 1038
C+ C TC+ L C D C EGC C D CV R++C C
Sbjct: 786 SPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 845
Query: 1039 NFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCET 1074
+F+G ++ D+ C+C D + C++
Sbjct: 846 HFQGVDYPPGDS---DIPSLGHCHCK--DGVMSCDS 876
Score = 182 bits (461), Expect = 4e-45
Identities = 185/718 (25%), Positives = 268/718 (37%), Gaps = 72/718 (10%)
Query: 1089 LYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNE 1148
+Y D+ C G H TFDG + L P SF + N+
Sbjct: 140 VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR-HEPEGQSFS---IQVHND 195
Query: 1149 DRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVV 1208
+ S + F IH A + V R+ LP +G ++ +V+
Sbjct: 196 PQCGSSPYTCSRAVSLFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQ--QLAGYVI 251
Query: 1209 VETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQ 1268
V + +D + + I + + T+GLCG N +P DDL G L V EF
Sbjct: 252 VRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVH 311
Query: 1269 SWVKRDTFCQVGCGDRC---PSCAKVEG--FSKVQQLCSLIPNQNAAFSKCHSKVNPTFF 1323
SW ++ G P C + V + C + F CH+ V+P F
Sbjct: 312 SWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL--LRPPFDACHAYVSPLPF 369
Query: 1324 YKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYT-SCTVTCPPNSH-YESC 1381
+C D C G V T C L YA C G + GWR CTV C + Y C
Sbjct: 370 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 429
Query: 1382 VSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW 1441
++ C C D CV+GC+C G + C+ P C C G Y P +
Sbjct: 430 IACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVV- 488
Query: 1442 NSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGA 1501
DC C C +C C ++ C G F TFDG
Sbjct: 489 KEDCNT-CTC-TSGKWECSTAVCPAE-------------------CSVTGDIHFTTFDGR 527
Query: 1502 FLRFPANCAFVLS------TICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQIL 1555
FPA C ++L+ T L + L N D ++++I Q+
Sbjct: 528 RYTFPATCQYILAKSRSSGTFTVTLQNAPCGL--NQDGACVQSVSVI---LHQDPRRQVT 582
Query: 1556 INDRNTVKVNGTQVNVPFITGLATKIYS-SEGFLVIDTSPDIQIYYNGFNV-IKISISER 1613
+ V + +P T A +I S FL + T+ +++ Y+ + + + + +R
Sbjct: 583 LTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQR 642
Query: 1614 LQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQY 1673
GLCG FNG+ DD+++ G P + + SWKT +C+ L
Sbjct: 643 WVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT--------LSACSPLVSGSP 694
Query: 1674 AAMCDNVHIQKMQ-GDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQLCG 1732
CD VH+Q C LT F PC L P+P++E C D C + LC
Sbjct: 695 LDPCD-VHLQAASYSVQACSVLTG--EMFAPCSAFLSPVPYFEQCRRDACRCGQPC-LCA 750
Query: 1733 SLAAYGEACRSFGILSTEWIEKENCSGVVE-----DPCVGADCPNRTCELGNGRELCG 1785
+LA Y CR G+ C+ E PCV A C RTC+ E CG
Sbjct: 751 TLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV-APC-GRTCQDLASPEACG 806
Score = 134 bits (337), Expect = 1e-30
Identities = 118/453 (26%), Positives = 183/453 (40%), Gaps = 52/453 (11%)
Query: 254 IDPANGCTSRGQFLRRGEVFWDDLNCTVKCRC-LDFNNEIY---------CQEASCSPYE 303
+D C G + G +F +D C C +F+ +Y C +C+
Sbjct: 444 VDSEIACVD-GCYCPNGLIF-EDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCT--- 498
Query: 304 VCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSV 363
GK+ +AV + C V G+ H+ TFDG + F +C Y+LA+ + S F+V
Sbjct: 499 ----SGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTV 550
Query: 364 EAKNE----HRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVK 419
+N ++ G+ V V + + ++ + + G V + D +P D
Sbjct: 551 TLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA--GDVLLFDQYKIIPPYTDDAFEI 608
Query: 420 IYQSGISTAVETDFGLLVTFDGQHYAS-ISVPGSYINSTCGLCGNYNKNPLDDFLRPDGR 478
S + V T+ G+ V +D + + V ++ T GLCG +N N DDFL P G
Sbjct: 609 RRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGV 668
Query: 479 PAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECG 538
P + G SW+ A SG CD +A + C L T C
Sbjct: 669 PESTPQLFGNSWKTLSACSPLVSG--SPLDPCDVHLQAASYSVQACSVL--TGEMFAPCS 724
Query: 539 TVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCP 598
+ P + C D C R LC + YA +C+ G+P+ D+R + + + C
Sbjct: 725 AFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPV-DFRARLPACA-LSCE 780
Query: 599 SFSHYSVCTSSCPDTCSDLTASRNCAT---------PCTEGCECNQGFVLSTSQ--CVPL 647
+ YS C + C TC DL + C C EGC C L T CVP
Sbjct: 781 ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPR 840
Query: 648 HKCGCDFDGHYYTMGEFFWATANCTVQCLCEEG 680
++C C F G Y G+ + C C++G
Sbjct: 841 NQCSCHFQGVDYPPGD---SDIPSLGHCHCKDG 870
Score = 112 bits (279), Expect = 5e-24
Identities = 104/403 (25%), Positives = 158/403 (39%), Gaps = 57/403 (14%)
Query: 984 CPENSHFEEC--------ITCTETCET--LTLGPICVDSCSEGCQCDEGYALLGSQCVTR 1033
CP F C ++ TCE L L C GC C +G G C
Sbjct: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 942
Query: 1034 SECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQ 1093
EC C ++G + Y G C T C + G + C
Sbjct: 943 EECPCTWKGKE-----------------YFPGDQVMSPCHTCVC--------QRGSFQCT 977
Query: 1094 ARTDAS-CIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDP 1152
AS C G HY TFDG PFDF +C + L S S F V +N +
Sbjct: 978 LHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV------KSTSDVSFSVIVENVNCYS 1031
Query: 1153 SLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVE-T 1211
S + K + + V G S+++ + S +L K +++ + GF +V
Sbjct: 1032 SGMICRKFISINV-GNSLIV---FDDDSGNPSPESFLDDK---QEVHTWRVGFFTLVHFP 1084
Query: 1212 DFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWV 1271
+ +++D +T + + Q GLCG ++ +++ P L ++ EFG SW
Sbjct: 1085 QEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWA 1144
Query: 1272 KRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDS 1331
+ + D C E F+K + CS++ ++ F CH V+ T+FY NCL D+
Sbjct: 1145 AVECPDTLDPRDMCVLNPLREPFAKKE--CSILLSE--VFEICHPVVDVTWFYSNCLTDT 1200
Query: 1332 --CIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTC 1372
C GG + C+ + YA C G+ V WR C C
Sbjct: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 84.3 bits (207), Expect = 1e-15
Identities = 82/338 (24%), Positives = 128/338 (37%), Gaps = 27/338 (7%)
Query: 258 NGCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAV 317
+GC LR G+ + +C C E + + SP C + F C+
Sbjct: 924 SGCACPQGLLRHGDACF----LPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLH 979
Query: 318 E-TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVS 376
STC +G+ HY TFDG F F G+C L + S FSV +N + S +
Sbjct: 980 PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS----FSVIVENVNCYSSGMI 1035
Query: 377 WVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVE-TDFGL 435
K +S+ V G +++ G + D V ++ G T V +
Sbjct: 1036 CRKFISINV-GNSLIVFDDDSGNPSPESFLD------DKQEVHTWRVGFFTLVHFPQEHI 1088
Query: 436 LVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHA 495
+ +D + + + GLCGN++ +++ P+ + + G SW A
Sbjct: 1089 TLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW----A 1144
Query: 496 DWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLC 555
+C +D C F C L + C VVD T F +C+ D C
Sbjct: 1145 AVECPD-TLDPRDMCVLNPLREPFAKKECSILLSEVFEI--CHPVVDVTWFYSNCLTDTC 1201
Query: 556 SVRDNG--TLLCQAIQAYALVCQALGIPIGDWRTQTGC 591
G C ++ AYA C G+ + DWRT C
Sbjct: 1202 GCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLC 1238
Score = 72.4 bits (176), Expect = 4e-12
Identities = 92/403 (22%), Positives = 142/403 (35%), Gaps = 58/403 (14%)
Query: 597 CPSFSHYSVCTSSCPD-------TCSD--LTASRNCATPCTEGCECNQGFVLSTSQCVPL 647
CP+ + C+ D TC L S + PC GC C QG + C
Sbjct: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 942
Query: 648 HKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFP 707
+C C + G Y G+ + + C+C+ G C C S
Sbjct: 943 EECPCTWKGKEYFPGDQVMSPCHT---CVCQRGS-FQCTLHPCAS--------------- 983
Query: 708 KRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLR 767
C ++ TFDG + F L+K+ + + I N +G +
Sbjct: 984 ----TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD-VSFSVIVENVNCYSSGMICRK 1038
Query: 768 GLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVE-SKGVVTVQ 826
+ I V + + +G F ++ +R T V + +T+
Sbjct: 1039 FISINVGNSLIVFDDD-------SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLL 1091
Query: 827 YSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICN 886
+ ++++ + GLCG ++ +E P N F SW E
Sbjct: 1092 WDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVE---- 1147
Query: 887 GECGDLLKACNNDSELLKFYR---SRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRL 943
C D L D +L R ++ C I+ + F CH VV+VT +Y CL
Sbjct: 1148 --CPDTLDP--RDMCVLNPLREPFAKKECSIL---LSEVFEICHPVVDVTWFYSNCLTDT 1200
Query: 944 --CQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLEC 984
C GG+ C SV+ YA C V V WRT CP +C
Sbjct: 1201 CGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 70.5 bits (171), Expect = 2e-11
Identities = 70/286 (24%), Positives = 114/286 (39%), Gaps = 30/286 (10%)
Query: 831 GLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCT---DNLAVFLESWTTFEEICN- 886
GL+ + S T GLCG + +A+++ L +G ++ A FL+SW + +
Sbjct: 2230 GLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSV 2289
Query: 887 GECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQS 946
G+ +C S C + SN +F CH V ++ + +
Sbjct: 2290 GQTRFRPDSCATTD--------CSPC--LRMVSNRTFSACHRFVPPESFCELWI----RD 2335
Query: 947 GGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECITCTE---TCETL 1003
+ C ++ Y + C V + WR D+CP C +S ++ C+T E TC+
Sbjct: 2336 TKYVQQPCVALTVYVAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG 2394
Query: 1004 TLGPICVDSC---SEGCQCDEGYAL---LGSQCVTRSECGC-NFEGHQLATNETFWVDLD 1056
LGP+ + C EGC C EG L + C+ ++C C + G A ET+ L
Sbjct: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454
Query: 1057 CQIFCYCSGTDNRVHCET-IPCKDDEYCMEEGGLYYCQARTDASCI 1101
C D V + P E C+ G + D C+
Sbjct: 2455 GCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2500
Score = 70.1 bits (170), Expect = 2e-11
Identities = 79/361 (21%), Positives = 128/361 (35%), Gaps = 49/361 (13%)
Query: 1402 CVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDP 1461
C+ GC C G + +G +C LP C C GK Y P S C C C +R QC
Sbjct: 922 CLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM-SPC-HTCVC-QRGSFQCTL 978
Query: 1462 RQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLP 1521
C S C A G +RTFDG F C L +
Sbjct: 979 HPC-------------------ASTCTAYGDRHYRTFDGLPFDFVGACKVHL---VKSTS 1016
Query: 1522 DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKI 1581
D+SF +I+ + + + + I+ +D +G F+
Sbjct: 1017 DVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDD-----SGNPSPESFLDDKQEVH 1071
Query: 1582 YSSEGFLVIDTSPD--IQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGK 1639
GF + P I + ++ + + + Q ++ GLCGNF+ ++ T
Sbjct: 1072 TWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENL 1131
Query: 1640 PVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKG 1699
+ + SW A C + + MC +++ C L +
Sbjct: 1132 ELTNPQEFGSSW---------AAVECPDTLDPR--DMCVLNPLREPFAKKECSIL--LSE 1178
Query: 1700 FFQPCYGLLDPLPFYESCYLDGCYSHKKFQ---LCGSLAAYGEACRSFGILSTEWIEKEN 1756
F+ C+ ++D FY +C D C + C S++AY C G+ + +W
Sbjct: 1179 VFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGV-AVDWRTPRL 1237
Query: 1757 C 1757
C
Sbjct: 1238 C 1238
Score = 68.2 bits (165), Expect = 8e-11
Identities = 81/368 (22%), Positives = 138/368 (37%), Gaps = 44/368 (11%)
Query: 1161 VDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYD 1220
+++T + + I R + V V+ + ++ P+ +I + ++ +D ++ ++
Sbjct: 2170 LNMTHLAHQVTIDR-FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHS 2228
Query: 1221 WKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNE---FGQSWVKRDTFC 1277
+ + ++ + +GLCG +G+ +DL + G + + F SW +
Sbjct: 2229 -SGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLT 2287
Query: 1278 QVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGA 1337
VG P S ++ S N FS CH V P F + + D+
Sbjct: 2288 SVGQTRFRPDSCATTDCSPCLRMVS-----NRTFSACHRFVPPESFCELWIRDTKY---- 2338
Query: 1338 VQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQP--RCA-AIRL 1394
VQ C L Y + C + + WR C C +S Y++CV+ C+P C I
Sbjct: 2339 VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILG 2397
Query: 1395 KSDCSHYCV--EGCHCDAGYVLNGKS---CILPHSCGCYSDGKYYEPKQLFWNSDCTRRC 1449
D H V EGC C G +L+ + CI C C WNS + C
Sbjct: 2398 PLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457
Query: 1450 RCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANC 1509
+ QC++ + + GC S + CL F L P
Sbjct: 2458 Q-----------HQCQAPDTIVPVD--LGCPSPRPESCL--------RFGEVALLLPTKD 2496
Query: 1510 AFVLSTIC 1517
L T+C
Sbjct: 2497 PCCLGTVC 2504
Score = 40.4 bits (93), Expect = 0.019
Identities = 69/305 (22%), Positives = 111/305 (36%), Gaps = 50/305 (16%)
Query: 1495 FRTFDGAFLRFPANCAFVLSTICQKLPDISF----QLIINFDKWSAPNLTIISPVYFYIN 1550
F TFDG+ + ++LS ++ + + W L +++ +
Sbjct: 2119 FVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHL--- 2175
Query: 1551 EEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYY---NGFNVIK 1607
Q+ I+ N Q P ++ +I + +I T DIQI + +G +++
Sbjct: 2176 AHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVE 2235
Query: 1608 ISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSS----VVLAQSWK-----TNGMQK 1658
S + + Q GLCG +GD +D +TL+ VV SW+ T+ Q
Sbjct: 2236 ASKTSKAQGH--GLCGICDGDAAND-LTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2292
Query: 1659 RPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCY 1718
R SC S CL++ + F C+ + P F E
Sbjct: 2293 RFRPDSCATTDCSP------------------CLRMVSNR-TFSACHRFVPPESFCELWI 2333
Query: 1719 LDGCYSHKKFQLCGSLAAYGEACRSFGILSTEWIEKENC-----SGVVEDPCVGADCPNR 1773
D Y Q C +L Y C F + EW + C S CV A P +
Sbjct: 2334 RDTKYVQ---QPCVALTVYVAMCHKFHV-CIEWRRSDYCPFLCSSDSTYQACVTACEPPK 2389
Query: 1774 TCELG 1778
TC+ G
Sbjct: 2390 TCQDG 2394
Score = 38.9 bits (89), Expect = 0.055
Identities = 60/294 (20%), Positives = 97/294 (32%), Gaps = 77/294 (26%)
Query: 459 GLCGNYNKNPLDDFLRPDGRPAMSVLDLG---ESWRVYHA-------DWKCDSGCVDNCT 508
GLCG + + +D DG D +SW+V + ++ DS +C+
Sbjct: 2246 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCS 2305
Query: 509 QCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAI 568
C F + C V P +F + D V+ C A+
Sbjct: 2306 PCLRMVSNRTFSA---------------CHRFVPPESFCELWIRDTKYVQQP----CVAL 2346
Query: 569 QAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCT 628
Y +C + I +WR + CP CS + + C T C
Sbjct: 2347 TVYVAMCHKFHVCI-EWRR-------------------SDYCPFLCSSDSTYQACVTACE 2386
Query: 629 ----------------------EGCECNQGFVL---STSQCVPLHKCGC-DFDGHYYTMG 662
EGC C++G +L ++ C+P KC C D G +G
Sbjct: 2387 PPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALG 2446
Query: 663 EFFWATANCTVQCLCEEGGDVYCFNKTCGS--GEVCAVEDGYQGCFPKRETVCL 714
E + ++ + Q C+ + + C S E C P ++ CL
Sbjct: 2447 ETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2500
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 236 bits (601), Expect = 2e-61
Identities = 200/761 (26%), Positives = 307/761 (40%), Gaps = 102/761 (13%)
Query: 723 TFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGG 782
TFDG + FP +Y + C R Y + ++ ++ L G R +V +K G
Sbjct: 743 TFDGDVFRFPGLCNYVFSEHC--RAAYEDFNVQLRRG------LVGSRPVVTRVVIKAQG 794
Query: 783 I----GASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLS 838
+ V +NGQ ELP+ L + ++ + V + V+T ++ + L
Sbjct: 795 LVLEASNGSVLINGQREELPYSRTG--LLVEQSGDYIKVSIRLVLTFLWNGEDSALLELD 852
Query: 839 TTYFNCTGGLCGFYNA-NASDEFCLPNGKCTDNLAVFLESWTTFEEICN-------GECG 890
Y N T GLCG +N A +EF N + T L+ E C G C
Sbjct: 853 PKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQFGNLQKLDGPTEQCPDPLPLPAGNCT 912
Query: 891 DLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNE 950
D C+ R+ G +F ECH +V+ TAY C LC+
Sbjct: 913 DEEGICH-----------RTLLG-------PAFAECHALVDSTAYLAACAQDLCRC---P 951
Query: 951 SELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECIT-CTETCETLTLGPIC 1009
+ C + Y+ C +A + WR + CP CP N +EC + CT+TC +C
Sbjct: 952 TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLC 1011
Query: 1010 VDSCSEGCQCDEGYA------LLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYC 1063
D C +GC C G + + S C+ +C C G Y
Sbjct: 1012 EDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRT-----------------YS 1054
Query: 1064 SGTDNRVHCETIPCKDDEYCMEEGGLYYCQ-ARTDASCIVSGYGHYLTFDGFPFDFQTSC 1122
GT C + C GGL+ CQ +C V G H T+D +D C
Sbjct: 1055 PGTSFNTTCSSCTCS--------GGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDC 1106
Query: 1123 PLILCTTGSRPSSDSFPKFVVTAKNE-----DRDPSLALWVKQVDVTVFGYSIVIHRAYK 1177
+L S+ +DS F V A+ D + L K V +++ G I
Sbjct: 1107 SYVL----SKKCADS--SFTVLAELRKCGLTDNENCL----KAVTLSLDGGDTAIRVQAD 1156
Query: 1178 HTVLVNSERLYLPLKLGQGKINIFS-FGFHVVVETDFGLKVVYDWKTFLSITV--PRSMQ 1234
V +NS +Y L L I +F+ F +VV+T GL+++ + + V + Q
Sbjct: 1157 GGVFLNS--IYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQ 1214
Query: 1235 NSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGCGDRCPSCAKVEGF 1294
GLCG +N N DD G++ ++ F +W + P VE
Sbjct: 1215 GQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLSVENE 1274
Query: 1295 SKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQT 1354
+ + CS + + N+AFS+CHS +NP F+ NC+FD+C + C+ L +Y C
Sbjct: 1275 NYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAA 1334
Query: 1355 QGITVTGWRN--YTSCTVTCPPNSHYESCVSVCQPRCAAIR---LKSDCSHYCVEGCHCD 1409
+G+ ++ WR+ T CP + Y V CQP C + + S V+GC C
Sbjct: 1335 KGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCP 1394
Query: 1410 AGYVLN-GKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRC 1449
AG LN +C+ C CY+ G P ++ + C
Sbjct: 1395 AGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSC 1435
Score = 211 bits (537), Expect = 6e-54
Identities = 196/770 (25%), Positives = 307/770 (39%), Gaps = 91/770 (11%)
Query: 322 CVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSW--VK 379
C +G+ HY TFDG +F F G C Y+ + C ++ F+V+ RRG S V
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHC--RAAYEDFNVQL----RRGLVGSRPVVT 786
Query: 380 ELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTF 439
+ ++ G L+ + S G V +N LP + + + QSG V L +
Sbjct: 787 RVVIKAQG---LVLEASNGSVLINGQREELPYSRT--GLLVEQSGDYIKVSIRLVLTFLW 841
Query: 440 DGQHYASISVPGSYINSTCGLCGNYNKNP-LDDFLRPDGRPAMSVLDLGESWRVYHADWK 498
+G+ A + + Y N TCGLCG++N P ++F + R ++ L G ++ +
Sbjct: 842 NGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNAR--LTPLQFGNLQKLDGPTEQ 899
Query: 499 CDSGC---VDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLC 555
C NCT + G + EC +VD TA++ +C DLC
Sbjct: 900 CPDPLPLPAGNCTDEEGICHRTLLGPAFA-----------ECHALVDSTAYLAACAQDLC 948
Query: 556 SVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCS 615
T C Y+ C G +WR C T CP + C S C DTCS
Sbjct: 949 RCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRT--CPLNMQHQECGSPCTDTCS 1003
Query: 616 DLTASRNCATPCTEGCECNQGFV------LSTSQCVPLHKCGCDFDGHYYTMGEFFWATA 669
+ ++ C C +GC C G ++ S C+PL +C C G Y+ G F T
Sbjct: 1004 NPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTC 1063
Query: 670 NCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASY 729
+ C C GG C + C C+V+ G + T+D Y
Sbjct: 1064 S---SCTCS-GGLWQCQDLPCPG--TCSVQGGAH-----------------ISTYDEKLY 1100
Query: 730 AFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVK 789
+ SY L K C + + ++ K L+ + + + + I V
Sbjct: 1101 DLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVF 1160
Query: 790 LNGQEVELPFFHPSGKLEIYRNKNSTTVESKGV---VTVQYSDIGLLYIRLSTTYFNCTG 846
LN +LP + + ++ + V G+ + VQ + +++RL +
Sbjct: 1161 LNSIYTQLPL--SAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMC 1218
Query: 847 GLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLKFY 906
GLCG +N N +D+F +G A F +W + C C+ E +
Sbjct: 1219 GLCGNFNQNQADDFTALSGVVEATGAAFANTWKA-QAACANARNSFEDPCSLSVENENY- 1276
Query: 907 RSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKN 966
+R C + DP NS+F CH ++N ++ C+F C +E LC +++ Y AC
Sbjct: 1277 -ARHWCSRLTDP-NSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAA 1334
Query: 967 ADVEVGPWRTYDFCP---LECPENSHFEECI-TCTETCETLTLGPICVDSCS------EG 1016
V++ WR C CP++ + + C TC L+ + +CS +G
Sbjct: 1335 KGVQLSDWRD-GVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADV---TCSVSFVPVDG 1390
Query: 1017 CQCDEGYALL-GSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSG 1065
C C G L CV EC C G LA E V D C C+G
Sbjct: 1391 CTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGE---VVHDEGAVCSCTG 1437
Score = 186 bits (472), Expect = 2e-46
Identities = 223/932 (23%), Positives = 344/932 (36%), Gaps = 176/932 (18%)
Query: 249 VDGKEIDPANGCTSRGQFLRRGEVFWDDLNCTVKCRCLD----FNNEIYCQEASCSPYEV 304
VDG P CT G + CT R FN C +CS
Sbjct: 1016 VDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTT--CSSCTCS---- 1069
Query: 305 CEPKGKFFYCSAVET-STCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSV 363
G + C + TC V G H T+D L+ G C+Y+L+++C +S F+V
Sbjct: 1070 ----GGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSS----FTV 1121
Query: 364 EAKNEHRRGSAV---SWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKI 420
A E R+ + +K +++ ++G I + G V +N + T LP L + +
Sbjct: 1122 LA--ELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLP--LSAANITL 1177
Query: 421 YQ-SGISTAVETDFGL--LVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDG 477
+ S V+T GL LV + + ++ CGLCGN+N+N DDF G
Sbjct: 1178 FTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSG 1237
Query: 478 RPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWEC 537
+ +W+ A + D C+ + E + +C L + C
Sbjct: 1238 VVEATGAAFANTWKAQAACANARNSFEDPCS---LSVENENYARHWCSRLTDPNSAFSRC 1294
Query: 538 GTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQC 597
++++P F +C++D C+ + LC A+ +Y C A G+ + DWR C
Sbjct: 1295 HSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNC 1354
Query: 598 PSFSHYSVCTSSCPDTCSDLT-ASRNCATPCT--EGCECNQG-FVLSTSQCVPLHKCGCD 653
P Y+ +C TC L+ A C+ +GC C G F+ CVP +C C
Sbjct: 1355 PKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCY 1414
Query: 654 FDGHYYTMGEFFW---ATANCT---VQCL------------------CEEGG-------- 681
G GE A +CT + CL C
Sbjct: 1415 AHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAEC 1474
Query: 682 -------DVYCFNKTCGSGEVCA---VEDGYQGCFPKRETVCLLSQN------------- 718
DV CF+ C SG VC V DG GC + + C+ ++
Sbjct: 1475 LRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCN 1534
Query: 719 ---------QVLH----------------TFDGASYAFPSEFSYTLLKT-CPERPEYLEI 752
+ H TFDG Y+F Y L + C + +
Sbjct: 1535 TCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTF 1594
Query: 753 DINKKKPDAGPAWLRGLRILVADQEVKIG-GIGASEVKLN---GQEVELPF---FHPSGK 805
I + G + + EV+ + + N +E + F P
Sbjct: 1595 RIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQS 1654
Query: 806 LEIYRNKNSTTVESKG-----VVTVQYSDIGL----------------LYIRLSTTYFNC 844
E+ + + ++G ++Y I L ++IRL Y
Sbjct: 1655 YELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQDYKGR 1714
Query: 845 TGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLK 904
GLCG ++ NA ++F + + F SW + C D L A +
Sbjct: 1715 VCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWK-----LSPSCPDAL-APKDPCTANP 1768
Query: 905 FYRS--RSRCGIINDPSNSSFLECHGVVNVTAYYRTCL--FRLCQSGGNESELCDSVARY 960
F +S + +C I++ P +F C V+ T YY C+ C SGG+ C +VA Y
Sbjct: 1769 FRKSWAQKQCSILHGP---TFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAY 1825
Query: 961 ASACKNADVEVGPWRTYDFCPLEC----PENS---HFEEC-ITCTETCETLTLGPICVDS 1012
A AC +A + V WRT D CPL C P H++ C C +TC + G VD
Sbjct: 1826 AQACHDAGLCVS-WRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPS-GHCLVDL 1883
Query: 1013 CS-EGC--QCDEGYALLGS---QCVTRSECGC 1038
EGC +C +CV ++CGC
Sbjct: 1884 PGLEGCYPKCPPSQPFFNEDQMKCV--AQCGC 1913
Score = 172 bits (435), Expect = 4e-42
Identities = 151/576 (26%), Positives = 234/576 (40%), Gaps = 71/576 (12%)
Query: 322 CVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKEL 381
C +G HY TFDG +F F G C Y+ + C ++ F+++ + SA + +
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHC--GAAYEDFNIQLRRSQE--SAAPTLSRV 136
Query: 382 SVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGT--VKIYQSGISTAVETDFGLLVTF 439
++V+G I + KGS LV PV L V I QS T VE GL++ +
Sbjct: 137 LMKVDGVVIQLTKGSV-------LVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMW 189
Query: 440 DGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKC 499
+ + + Y N TCGLCG++N P+ L ++ ++ G ++ +C
Sbjct: 190 NHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTK-LTPMEFGNLQKMDDPTEQC 248
Query: 500 DSGCVD---NCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCS 556
+ NC+ E L G + G C +VD +++ +C DLC
Sbjct: 249 QDPVPEPPRNCSTGFGICEELLHGQLFSG-----------CVALVDVGSYLEACRQDLCF 297
Query: 557 VRDNGTL--LCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTC 614
D L +C + Y+ C G DWR C +CP+ Y C S C DTC
Sbjct: 298 CEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQ--KCPNNMQYHECRSPCADTC 355
Query: 615 SDLTASRNCATPCTEGCECNQGFVL---STSQCVPLHKCGCDFDGHYYTMGEFFWATANC 671
S+ SR C C GC C +G VL + CVP+ KC C ++G Y G + + +C
Sbjct: 356 SNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDC 413
Query: 672 TVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAF 731
T C C GG C C C+V G TFDG Y
Sbjct: 414 T-NCTC-SGGRWSCQEVPCPG--TCSVLGGAH-----------------FSTFDGKQYTV 452
Query: 732 PSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVKLN 791
+ SY L K C + ++ + L+ + + + + + + EV LN
Sbjct: 453 HGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVFLN 512
Query: 792 GQEVELP-------FFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNC 844
+LP F PS I + + + V T+Q L+++L+
Sbjct: 513 QIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQ------LFMQLAPKLRGQ 566
Query: 845 TGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTT 880
T GLCG +N+ +D+F +G A F ++ T
Sbjct: 567 TCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT 602
Score = 162 bits (409), Expect = 4e-39
Identities = 159/679 (23%), Positives = 251/679 (36%), Gaps = 96/679 (14%)
Query: 1100 CIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVK 1159
C G HY TFDG F F C + S ++ F V + L
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVF----SEHCRAAYEDFNVQLRR-----GLVGSRP 783
Query: 1160 QVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVY 1219
V V ++ A +VL+N +R LP + + + G ++ V L ++
Sbjct: 784 VVTRVVIKAQGLVLEASNGSVLINGQREELPYS--RTGLLVEQSGDYIKVSIRLVLTFLW 841
Query: 1220 DWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQV 1279
+ + + + N T GLCG +NG P + NEF + R T Q
Sbjct: 842 NGEDSALLELDPKYANQTCGLCGDFNGLP-------------AFNEF-YAHNARLTPLQF 887
Query: 1280 G-----------CGDRCP----SCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFY 1324
G C D P +C EG L AF++CH+ V+ T +
Sbjct: 888 GNLQKLDGPTEQCPDPLPLPAGNCTDEEGICHRTLL-------GPAFAECHALVDSTAYL 940
Query: 1325 KNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSV 1384
C D C C+ Y+ C G WR C TCP N ++ C S
Sbjct: 941 AACAQDLC---RCPTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSP 997
Query: 1385 CQPRCAAIRLKSDCSHYCVEGCHCDAGYV------LNGKSCILPHSCGCYSDGKYYEPKQ 1438
C C+ + C +CV+GC C G + C+ C C G+ Y P
Sbjct: 998 CTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGT 1057
Query: 1439 LFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTF 1498
F N+ C+ C C + QC C C GG T+
Sbjct: 1058 SF-NTTCSS-CTC-SGGLWQCQDLPCPGT-------------------CSVQGGAHISTY 1095
Query: 1499 DGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWS-APNLTIISPVYFYIN--EEQIL 1555
D +C++VLS C D SF ++ K N + V ++ + I
Sbjct: 1096 DEKLYDLHGDCSYVLSKKCA---DSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIR 1152
Query: 1556 INDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISI--SER 1613
+ V +N +P T S F+V+ T +Q+ ++++ +
Sbjct: 1153 VQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPA 1212
Query: 1614 LQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQY 1673
Q ++CGLCGNFN + DD+ L G + A +WK +C + + +
Sbjct: 1213 HQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQA--------ACANAR-NSF 1263
Query: 1674 AAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQ-LCG 1732
C + +C +LTD F C+ +++P PF+ +C D C + LC
Sbjct: 1264 EDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCA 1323
Query: 1733 SLAAYGEACRSFGILSTEW 1751
+L++Y AC + G+ ++W
Sbjct: 1324 ALSSYVHACAAKGVQLSDW 1342
Score = 150 bits (380), Expect = 1e-35
Identities = 148/562 (26%), Positives = 227/562 (40%), Gaps = 74/562 (13%)
Query: 723 TFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGG 782
TFDG + FP +Y + C E I + + + A P R L +K+ G
Sbjct: 91 TFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLSRVL--------MKVDG 142
Query: 783 I----GASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLS 838
+ V +NG V LPF SG L I ++ + T VE++ + + ++ L + L
Sbjct: 143 VVIQLTKGSVLVNGHPVLLPFSQ-SGVL-IQQSSSYTKVEARLGLVLMWNHDDSLLLELD 200
Query: 839 TTYFNCTGGLCGFYNAN-ASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACN 897
T Y N T GLCG +N E N K T L+ E C + + C+
Sbjct: 201 TKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDDPTEQCQDPVPEPPRNCS 260
Query: 898 NDSELLKFYRSRSRCGIINDPSNSS-FLECHGVVNVTAYYRTCLFRLCQSGGNE--SELC 954
GI + + F C +V+V +Y C LC + S +C
Sbjct: 261 TGF------------GICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVC 308
Query: 955 DSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECIT-CTETCETLTLGPICVDSC 1013
++A Y+ C +A WR DFCP +CP N + EC + C +TC C D C
Sbjct: 309 HTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHC 368
Query: 1014 SEGCQCDEGYAL--LG-SQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRV 1070
GC C EG L +G + CV S+C C + G A T+ DC C CSG R
Sbjct: 369 VAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDC-TNCTCSG--GRW 423
Query: 1071 HCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTG 1130
C+ +PC +C V G H+ TFDG + C +L
Sbjct: 424 SCQEVPC-------------------PGTCSVLGGAHFSTFDGKQYTVHGDCSYVL---- 460
Query: 1131 SRP-SSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYL 1189
++P S +F + D L K V +++ G V+ V +N ++Y
Sbjct: 461 TKPCDSSAFTVLAELRRCGLTDSETCL--KSVTLSLDGAQTVVVIKASGEVFLN--QIYT 516
Query: 1190 PLKLGQGKINIF-SFGFHVVVETDFG----LKVVYDWKTFLSITVPRSMQNSTYGLCGRY 1244
L + + IF F ++ +T G L++V + F+ + ++ T GLCG +
Sbjct: 517 QLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLA--PKLRGQTCGLCGNF 574
Query: 1245 NGNPDDDLEMPMGLLASSVNEF 1266
N DD G++ ++ F
Sbjct: 575 NSIQADDFRTLSGVVEATAAAF 596
Score = 144 bits (364), Expect = 7e-34
Identities = 143/572 (25%), Positives = 217/572 (37%), Gaps = 68/572 (11%)
Query: 1100 CIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKN--EDRDPSLALW 1157
C G HY TFDG F F C + S ++ F + + E P+L+
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVF----SEHCGAAYEDFNIQLRRSQESAAPTLSRV 136
Query: 1158 VKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKV 1217
+ +VD V + K +VLVN + LP Q + I + VE GL +
Sbjct: 137 LMKVDGVVIQLT-------KGSVLVNGHPVLLPFS--QSGVLIQQSSSYTKVEARLGLVL 187
Query: 1218 VYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVN----EFGQSWVKR 1273
+++ L + + N T GLCG +NG P + LL+ + EFG
Sbjct: 188 MWNHDDSLLLELDTKYANKTCGLCGDFNGMP-----VVSELLSHNTKLTPMEFGNLQKMD 242
Query: 1274 DTFCQVGCGDRCPSCAK--VEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDS 1331
D Q C D P + GF ++L FS C + V+ + + C D
Sbjct: 243 DPTEQ--CQDPVPEPPRNCSTGFGICEELL-----HGQLFSGCVALVDVGSYLEACRQDL 295
Query: 1332 CI--DGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRC 1389
C D + C L Y+ C G WR C CP N Y C S C C
Sbjct: 296 CFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTC 355
Query: 1390 AAIRLKSDCSHYCVEGCHCDAGYVLNG---KSCILPHSCGCYSDGKYYEPKQLFWNSDCT 1446
+ C +CV GC C G VL+ C+ C C +G Y P + ++DCT
Sbjct: 356 SNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY-STDCT 414
Query: 1447 RRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFP 1506
C C C C C GG F TFDG
Sbjct: 415 -NCTC-SGGRWSCQEVPCPGT-------------------CSVLGGAHFSTFDGKQYTVH 453
Query: 1507 ANCAFVLSTICQKLPDISFQLIINFDKWS-APNLTIISPVYFYINEEQ--ILINDRNTVK 1563
+C++VL+ C +F ++ + + T + V ++ Q ++I V
Sbjct: 454 GDCSYVLTKPCD---SSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVF 510
Query: 1564 VNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKI--SISERLQNKVCGL 1621
+N +P T S F++ TS +Q+ +++ ++ +L+ + CGL
Sbjct: 511 LNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGL 570
Query: 1622 CGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKT 1653
CGNFN DD+ TL G ++ ++KT
Sbjct: 571 CGNFNSIQADDFRTLSGVVEATAAAFFNTFKT 602
Score = 127 bits (320), Expect = 9e-29
Identities = 128/515 (24%), Positives = 193/515 (37%), Gaps = 98/515 (19%)
Query: 982 LECPENSHFEECITCTETCETLTLGPICVDS-CSEGCQCDEGYALLGSQ-CVTRSECGCN 1039
L+C +S C +C TL +G C + C GC C G GS C+ +C C
Sbjct: 1460 LDCSNSSAGTPGAECLRSCHTLDVG--CFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCV 1517
Query: 1040 FEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTD-A 1098
H AT Y G RV C T C++ + C R
Sbjct: 1518 ---HNEAT--------------YKPGETIRVDCNTCTCRNRRW--------ECSHRLCLG 1552
Query: 1099 SCIVSGYGHYLTFDGFPFDFQTSCPLIL----------------------CTTGSRPSSD 1136
+C+ G GH++TFDG + F+ SC IL C T S
Sbjct: 1553 TCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSK 1612
Query: 1137 SFPKFVVT-----------AKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSE 1185
+ FV A NE ++ +Q + Y +++ V
Sbjct: 1613 AIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKAVARGPG 1672
Query: 1186 RLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYN 1245
G I G +V+ET G+ V +D KT + I + + + GLCG ++
Sbjct: 1673 --------GDPPYKIRYMGIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFD 1723
Query: 1246 GNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIP 1305
N +D + EFG SW K C + P A S Q+ CS++
Sbjct: 1724 DNAINDFATRSRSVVGDALEFGNSW-KLSPSCPDALAPKDPCTANPFRKSWAQKQCSIL- 1781
Query: 1306 NQNAAFSKCHSKVNPTFFYKNCLFDSCI--DGGAVQTACSWLQNYASTCQTQGITVTGWR 1363
F+ C S+V+ T +Y+ C+ D+C GG + C+ + YA C G+ V+ WR
Sbjct: 1782 -HGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVS-WR 1839
Query: 1364 NYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPH 1423
+C + C + + C QP C C++ C +G+ L LP
Sbjct: 1840 TPDTCPLFCDFYNPHGGCEWHYQP----------CGAPCLKTCRNPSGHCL----VDLPG 1885
Query: 1424 SCGCYSDGKYYEPKQLFWNSD---CTRRCRCFRRN 1455
GCY P Q F+N D C +C C+ ++
Sbjct: 1886 LEGCYPK---CPPSQPFFNEDQMKCVAQCGCYDKD 1917
Score = 119 bits (299), Expect = 2e-26
Identities = 116/423 (27%), Positives = 173/423 (40%), Gaps = 62/423 (14%)
Query: 305 CEPKGKFFYCS-AVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQ-CLQTSSLPFFS 362
C + + + CS + TCV +G+ H+ TFDG + F+GSC Y+LA+ C ++ F
Sbjct: 1536 CTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFR 1595
Query: 363 VEAKNEH--RRGSAVSWVKELSVEVNGYKILIP-----------KGSYGRVKVNDLVTSL 409
+ +N G+ S +L VEV + + S G + + S
Sbjct: 1596 IVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQSY 1655
Query: 410 PVTLDLGTVK-------------IYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINS 456
+ L GT K I GI +ET G+ V++D + I + Y
Sbjct: 1656 ELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGR 1714
Query: 457 TCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEA 516
CGLCGN++ N ++DF L+ G S WK C D D T
Sbjct: 1715 VCGLCGNFDDNAINDFATRSRSVVGDALEFGNS-------WKLSPSCPDALAPKDPCTAN 1767
Query: 517 LY---FGSDYCGFLNKTDGPLW-ECGTVVDPTAFVHSCVYDLCSVRDNG--TLLCQAIQA 570
+ + C L+ GP + C + VD T + +CV D C+ G C A+ A
Sbjct: 1768 PFRKSWAQKQCSILH---GPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAA 1824
Query: 571 YALVCQALGIPIGDWRTQTGCVSTVQCPSFS-------HYSVCTSSCPDTCSDLTASRNC 623
YA C G+ + WRT C + C ++ HY C + C TC + +
Sbjct: 1825 YAQACHDAGLCV-SWRTPDTC--PLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLV 1881
Query: 624 ATPCTEGC--EC--NQGFVLSTSQCVPLHKCGC-DFDGHYYTMGEFFWATANCTVQCLCE 678
P EGC +C +Q F + Q + +CGC D DG+YY +G NC C C
Sbjct: 1882 DLPGLEGCYPKCPPSQPF-FNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENCQ-SCNCT 1939
Query: 679 EGG 681
G
Sbjct: 1940 PSG 1942
Score = 113 bits (283), Expect = 2e-24
Identities = 129/480 (26%), Positives = 196/480 (40%), Gaps = 61/480 (12%)
Query: 256 PANGCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCS---------PYEVCE 306
PA GC + LR+ W NCTV RC+ N + + P +V +
Sbjct: 5325 PAPGCDNAIP-LRQVNETWTLENCTV-ARCVGDNRVVLLDPKPVANVTCVNKHLPIKVSD 5382
Query: 307 PKGK--FFY---CSAVE-------TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQ 354
P F Y C V C ++G HY TFDG + F+G+C Y+L R+
Sbjct: 5383 PSQPCDFHYECECECVGGRGITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREI-- 5440
Query: 355 TSSLPFFSVEAKNEHRRGSAVSWV------KELSVEVNGYKILIPKGS-YGRVKVNDLVT 407
+ S+ N + SA + + LS+ I++ +G+ + L
Sbjct: 5441 HARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFD 5500
Query: 408 SLPVTLDLGTVKIYQSGI-STAVETDF---GLLVTFDGQHYASISVPGSYINSTCGLCGN 463
+PV+ + S + +T + D G+ VTF+GQ + + + N+T G CG
Sbjct: 5501 QIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGT 5560
Query: 464 YNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSD- 522
N DD L+ DG A S D+ ++W V D + D GC A+ A S
Sbjct: 5561 CTNNQRDDCLQRDGTTAASCKDMAKTWLV--PDSRKD-GCWAPTGTPPTASPAAPVSSTP 5617
Query: 523 ---------YCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYAL 573
C + EC +V P F ++C+ D C R + CQ+++AYA
Sbjct: 5618 TPTPCPPQPLCDLM--LSQVFAECHNLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAE 5673
Query: 574 VCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCEC 633
+C+A G+ DWR TG + + CP Y C P TC+ S EGC C
Sbjct: 5674 LCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQ-LEGMAEGCFC 5731
Query: 634 NQGFVLSTSQC-VPLHKCGC-DFDGHYYTMGEFFWATANCTVQCLCEEGG-DVYCFNKTC 690
+ +L + + + C C DG GE + +NC C+C+EG V C C
Sbjct: 5732 PEDQILFNAHMGICVQACPCVGPDGFPKFPGERW--VSNCQ-SCVCDEGSVSVQCKPLPC 5788
Score = 100 bits (249), Expect = 2e-20
Identities = 98/392 (25%), Positives = 160/392 (40%), Gaps = 40/392 (10%)
Query: 1100 CIVSGYGHYLTFDGFPFDFQTSCPLILCTT-GSRPSSDSF-------PKFVVTAKNEDRD 1151
C + G HY TFDG + F+ +C +L +R + S A R
Sbjct: 5410 CSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAARC 5469
Query: 1152 P-SLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGK----INIFSFGFH 1206
P +L++ K +D+ + ++H + +L + +P+ G K +++
Sbjct: 5470 PRALSIHYKSMDIVLT--VTMVHGKEEGLILFDQ----IPVSSGFSKNGVLVSVLGTTTM 5523
Query: 1207 VVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEF 1266
V G+ V ++ + F + N+T G CG N DD G A+S +
Sbjct: 5524 RVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDM 5583
Query: 1267 GQSWVKRDT-----FCQVGCGDRCPSCAKVEGF-----SKVQQLCSLIPNQNAAFSKCHS 1316
++W+ D+ + G A V Q LC L+ +Q F++CH+
Sbjct: 5584 AKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQ--VFAECHN 5641
Query: 1317 KVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTS--CTVTCPP 1374
V P F+ C+ D C G ++ C L+ YA C+ +G+ + WR T C +TCPP
Sbjct: 5642 LVPPGPFFNACISDHC--RGRLEVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCPP 5698
Query: 1375 NSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVL-NGKSCILPHSCGCYSDGKY 1433
Y+ C + QP R +S EGC C +L N I +C C +
Sbjct: 5699 TKVYKPCGPI-QPATCNSRNQSPQLEGMAEGCFCPEDQILFNAHMGICVQACPCVGPDGF 5757
Query: 1434 YEPKQLFWNSDCTRRCRCFRRNV-IQCDPRQC 1464
+ W S+C + C C +V +QC P C
Sbjct: 5758 PKFPGERWVSNC-QSCVCDEGSVSVQCKPLPC 5788
Score = 73.6 bits (179), Expect = 2e-12
Identities = 94/386 (24%), Positives = 135/386 (34%), Gaps = 55/386 (14%)
Query: 1399 SHYCVEGCHCDAGYVLNGKS-CILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVI 1457
S +CV GC C G V +G CI C C + Y+P + DC C C R
Sbjct: 1487 STHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETI-RVDCNT-CTCRNRRW- 1543
Query: 1458 QCDPRQCKS------DEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAF 1511
+C R C D +G R F Y LA T G F N
Sbjct: 1544 ECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPC 1603
Query: 1512 -VLSTICQKLPDISFQLIINFDKWSAPNLTIISPVYFYIN----------EEQILINDRN 1560
T C K + F + S P+ P + + LI
Sbjct: 1604 GTTGTTCSKAIKL-FVEVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQSYELILQEG 1662
Query: 1561 TVKV--NGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKV 1618
T K G + P+ KI FLVI+T + + ++ + I + + + +V
Sbjct: 1663 TFKAVARGPGGDPPY------KIRYMGIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGRV 1715
Query: 1619 CGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAP----SCNELQFSQYA 1674
CGLCGNF+ + +D+ T V ++ SWK + LAP + N + S
Sbjct: 1716 CGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQ 1775
Query: 1675 AMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQ---LC 1731
C +H F C +D +YE+C D C C
Sbjct: 1776 KQCSILH----------------GPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFC 1819
Query: 1732 GSLAAYGEACRSFGILSTEWIEKENC 1757
++AAY +AC G L W + C
Sbjct: 1820 TAVAAYAQACHDAG-LCVSWRTPDTC 1844
Score = 70.5 bits (171), Expect = 2e-11
Identities = 73/275 (26%), Positives = 114/275 (41%), Gaps = 25/275 (9%)
Query: 1487 CLAAGGGVFRTFDGAFLRFPANCAFVLSTIC-QKLPDISFQLIINFDKWSAPNLTIISPV 1545
C G ++TFDG RFP C +V S C D + QL + + +AP L S V
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQES-AAPTL---SRV 136
Query: 1546 YFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNV 1605
++ I + + +V VNG V +PF I S + ++ + + +N +
Sbjct: 137 LMKVDGVVIQLT-KGSVLVNGHPVLLPFSQS-GVLIQQSSSYTKVEARLGLVLMWNHDDS 194
Query: 1606 IKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSC 1665
+ + + + NK CGLCG+FNG PVVS + L+ + K M+ L
Sbjct: 195 LLLELDTKYANKTCGLCGDFNG-----------MPVVSEL-LSHNTKLTPMEFGNLQKMD 242
Query: 1666 NELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSH 1725
+ + Q + G G C +L + F C L+D + E+C D C+
Sbjct: 243 DPTEQCQDPVPEPPRNCST--GFGICEELLHGQ-LFSGCVALVDVGSYLEACRQDLCFCE 299
Query: 1726 KKFQL---CGSLAAYGEACRSFGILSTEWIEKENC 1757
L C +LA Y C G L +W + C
Sbjct: 300 DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFC 334
Score = 66.2 bits (160), Expect = 3e-10
Identities = 63/222 (28%), Positives = 99/222 (44%), Gaps = 23/222 (10%)
Query: 264 GQFLRRGEVFWDDLNCT-----VKCRCLDFNNEIYCQEASCSP-YEVCEPKGKFFYCSAV 317
G F G V DD+ T KC C+ +N Y A+ S C G + C V
Sbjct: 371 GCFCPEGTVL-DDIGQTGCVPVSKCACV-YNGAAYAPGATYSTDCTNCTCSGGRWSCQEV 428
Query: 318 ET-STCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRR---GS 373
TC V G H+ TFDG + G C+Y+L + C ++ F+V A E RR
Sbjct: 429 PCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSA----FTVLA--ELRRCGLTD 482
Query: 374 AVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQ-SGISTAVETD 432
+ + +K +++ ++G + ++ + G V +N + T LP++ V I++ S +T
Sbjct: 483 SETCLKSVTLSLDGAQTVVVIKASGEVFLNQIYTQLPIS--AANVTIFRPSTFFIIAQTS 540
Query: 433 FGLLVTFD--GQHYASISVPGSYINSTCGLCGNYNKNPLDDF 472
GL + + + TCGLCGN+N DDF
Sbjct: 541 LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDF 582
Score = 58.5 bits (140), Expect = 7e-08
Identities = 107/461 (23%), Positives = 159/461 (34%), Gaps = 63/461 (13%)
Query: 666 WATANCTV-QCLCEEG---------GDVYCFNK-----------TCGSGEVCAVED-GYQ 703
W NCTV +C+ + +V C NK C C E G +
Sbjct: 5342 WTLENCTVARCVGDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECECVGGR 5401
Query: 704 GCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPER----PEYLEIDINKKKP 759
G P +C + TFDG SY F +Y L++ R YL+
Sbjct: 5402 GITPGAG-ICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASA 5460
Query: 760 DAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVES 819
A A R R L K I + ++G+E L F + +KN V
Sbjct: 5461 TAAAAAARCPRALSI--HYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGF-SKNGVLVSV 5517
Query: 820 KGVVTVQYSDIGLLYIRLS------------TTYFNCTGGLCGFYNANASDEFCLPNGKC 867
G T++ DI L + ++ + + N T G CG N D+ +G
Sbjct: 5518 LGTTTMRV-DIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTT 5576
Query: 868 TDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPS-----NSS 922
+ ++W + +G C S + + P +
Sbjct: 5577 AASCKDMAKTWLVPDSRKDG-CWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQV 5635
Query: 923 FLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWR--TYDFC 980
F ECH +V ++ C+ C+ G C S+ YA C+ V WR T C
Sbjct: 5636 FAECHNLVPPGPFFNACISDHCR--GRLEVPCQSLEAYAELCRARGV-CSDWRGATGGLC 5692
Query: 981 PLECPENSHFEECITC-TETCETLTLGPICVDSCSEGCQCDEGYALLGSQ---CVTRSEC 1036
L CP ++ C TC + P ++ +EGC C E L + CV C
Sbjct: 5693 DLTCPPTKVYKPCGPIQPATCNSRNQSP-QLEGMAEGCFCPEDQILFNAHMGICVQACPC 5751
Query: 1037 GCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPC 1077
+G E WV +CQ C C V C+ +PC
Sbjct: 5752 -VGPDGFPKFPGER-WVS-NCQ-SCVCDEGSVSVQCKPLPC 5788
Score = 54.7 bits (130), Expect = 1e-06
Identities = 76/316 (24%), Positives = 120/316 (37%), Gaps = 37/316 (11%)
Query: 1460 DPRQ-CKSDEECALRN-GVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLST-I 1516
DP Q C EC G RG + C GG + TFDG F NC +VL I
Sbjct: 5382 DPSQPCDFHYECECECVGGRG-ITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREI 5440
Query: 1517 CQKLPDISFQLIINFDKWSAPNLT------------------IISPVYFYINEEQILIND 1558
+ ++S L ++ SA +++ + EE +++ D
Sbjct: 5441 HARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFD 5500
Query: 1559 RNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERL-QNK 1617
+ V +G N G+ + + V + + + +NG V + + L N
Sbjct: 5501 QIPVS-SGFSKN-----GVLVSVLGTTTMRVDIPALGVSVTFNG-QVFQARLPYSLFHNN 5553
Query: 1618 VCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPL-APSCNELQFSQYAAM 1676
G CG + DD + G S +A++W +K AP+ S A +
Sbjct: 5554 TEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPV 5613
Query: 1677 CDNVHIQKMQGDGYC-LKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQLCGSLA 1735
C L L+ + F C+ L+ P PF+ +C D C + C SL
Sbjct: 5614 SSTPTPTPCPPQPLCDLMLSQV---FAECHNLVPPGPFFNACISDHCRGRLEVP-CQSLE 5669
Query: 1736 AYGEACRSFGILSTEW 1751
AY E CR+ G+ S +W
Sbjct: 5670 AYAELCRARGVCS-DW 5684
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 236 bits (601), Expect = 2e-61
Identities = 200/761 (26%), Positives = 307/761 (40%), Gaps = 102/761 (13%)
Query: 723 TFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGG 782
TFDG + FP +Y + C R Y + ++ ++ L G R +V +K G
Sbjct: 87 TFDGDVFRFPGLCNYVFSEHC--RAAYEDFNVQLRRG------LVGSRPVVTRVVIKAQG 138
Query: 783 I----GASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLS 838
+ V +NGQ ELP+ L + ++ + V + V+T ++ + L
Sbjct: 139 LVLEASNGSVLINGQREELPYSRTG--LLVEQSGDYIKVSIRLVLTFLWNGEDSALLELD 196
Query: 839 TTYFNCTGGLCGFYNA-NASDEFCLPNGKCTDNLAVFLESWTTFEEICN-------GECG 890
Y N T GLCG +N A +EF N + T L+ E C G C
Sbjct: 197 PKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQFGNLQKLDGPTEQCPDPLPLPAGNCT 256
Query: 891 DLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNE 950
D C+ R+ G +F ECH +V+ TAY C LC+
Sbjct: 257 DEEGICH-----------RTLLG-------PAFAECHALVDSTAYLAACAQDLCRC---P 295
Query: 951 SELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECIT-CTETCETLTLGPIC 1009
+ C + Y+ C +A + WR + CP CP N +EC + CT+TC +C
Sbjct: 296 TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLC 355
Query: 1010 VDSCSEGCQCDEGYA------LLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYC 1063
D C +GC C G + + S C+ +C C G Y
Sbjct: 356 EDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRT-----------------YS 398
Query: 1064 SGTDNRVHCETIPCKDDEYCMEEGGLYYCQ-ARTDASCIVSGYGHYLTFDGFPFDFQTSC 1122
GT C + C GGL+ CQ +C V G H T+D +D C
Sbjct: 399 PGTSFNTTCSSCTCS--------GGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDC 450
Query: 1123 PLILCTTGSRPSSDSFPKFVVTAKNE-----DRDPSLALWVKQVDVTVFGYSIVIHRAYK 1177
+L S+ +DS F V A+ D + L K V +++ G I
Sbjct: 451 SYVL----SKKCADS--SFTVLAELRKCGLTDNENCL----KAVTLSLDGGDTAIRVQAD 500
Query: 1178 HTVLVNSERLYLPLKLGQGKINIFS-FGFHVVVETDFGLKVVYDWKTFLSITV--PRSMQ 1234
V +NS +Y L L I +F+ F +VV+T GL+++ + + V + Q
Sbjct: 501 GGVFLNS--IYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQ 558
Query: 1235 NSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGCGDRCPSCAKVEGF 1294
GLCG +N N DD G++ ++ F +W + P VE
Sbjct: 559 GQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLSVENE 618
Query: 1295 SKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQT 1354
+ + CS + + N+AFS+CHS +NP F+ NC+FD+C + C+ L +Y C
Sbjct: 619 NYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAA 678
Query: 1355 QGITVTGWRN--YTSCTVTCPPNSHYESCVSVCQPRCAAIR---LKSDCSHYCVEGCHCD 1409
+G+ ++ WR+ T CP + Y V CQP C + + S V+GC C
Sbjct: 679 KGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCP 738
Query: 1410 AGYVLN-GKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRC 1449
AG LN +C+ C CY+ G P ++ + C
Sbjct: 739 AGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSC 779
Score = 211 bits (537), Expect = 6e-54
Identities = 196/770 (25%), Positives = 307/770 (39%), Gaps = 91/770 (11%)
Query: 322 CVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSW--VK 379
C +G+ HY TFDG +F F G C Y+ + C ++ F+V+ RRG S V
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHC--RAAYEDFNVQL----RRGLVGSRPVVT 130
Query: 380 ELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTF 439
+ ++ G L+ + S G V +N LP + + + QSG V L +
Sbjct: 131 RVVIKAQG---LVLEASNGSVLINGQREELPYSRT--GLLVEQSGDYIKVSIRLVLTFLW 185
Query: 440 DGQHYASISVPGSYINSTCGLCGNYNKNP-LDDFLRPDGRPAMSVLDLGESWRVYHADWK 498
+G+ A + + Y N TCGLCG++N P ++F + R ++ L G ++ +
Sbjct: 186 NGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNAR--LTPLQFGNLQKLDGPTEQ 243
Query: 499 CDSGC---VDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLC 555
C NCT + G + EC +VD TA++ +C DLC
Sbjct: 244 CPDPLPLPAGNCTDEEGICHRTLLGPAFA-----------ECHALVDSTAYLAACAQDLC 292
Query: 556 SVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCS 615
T C Y+ C G +WR C T CP + C S C DTCS
Sbjct: 293 RCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRT--CPLNMQHQECGSPCTDTCS 347
Query: 616 DLTASRNCATPCTEGCECNQGFV------LSTSQCVPLHKCGCDFDGHYYTMGEFFWATA 669
+ ++ C C +GC C G ++ S C+PL +C C G Y+ G F T
Sbjct: 348 NPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTC 407
Query: 670 NCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASY 729
+ C C GG C + C C+V+ G + T+D Y
Sbjct: 408 S---SCTCS-GGLWQCQDLPCPG--TCSVQGGAH-----------------ISTYDEKLY 444
Query: 730 AFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVK 789
+ SY L K C + + ++ K L+ + + + + I V
Sbjct: 445 DLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVF 504
Query: 790 LNGQEVELPFFHPSGKLEIYRNKNSTTVESKGV---VTVQYSDIGLLYIRLSTTYFNCTG 846
LN +LP + + ++ + V G+ + VQ + +++RL +
Sbjct: 505 LNSIYTQLPL--SAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMC 562
Query: 847 GLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLKFY 906
GLCG +N N +D+F +G A F +W + C C+ E +
Sbjct: 563 GLCGNFNQNQADDFTALSGVVEATGAAFANTWKA-QAACANARNSFEDPCSLSVENENY- 620
Query: 907 RSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKN 966
+R C + DP NS+F CH ++N ++ C+F C +E LC +++ Y AC
Sbjct: 621 -ARHWCSRLTDP-NSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAA 678
Query: 967 ADVEVGPWRTYDFCP---LECPENSHFEECI-TCTETCETLTLGPICVDSCS------EG 1016
V++ WR C CP++ + + C TC L+ + +CS +G
Sbjct: 679 KGVQLSDWRD-GVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADV---TCSVSFVPVDG 734
Query: 1017 CQCDEGYALL-GSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSG 1065
C C G L CV EC C G LA E V D C C+G
Sbjct: 735 CTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGE---VVHDEGAVCSCTG 781
Score = 194 bits (492), Expect = 1e-48
Identities = 223/909 (24%), Positives = 341/909 (37%), Gaps = 164/909 (18%)
Query: 249 VDGKEIDPANGCTSRGQFLRRGEVFWDDLNCTVKCRCLD----FNNEIYCQEASCSPYEV 304
VDG P CT G + CT R FN C +CS
Sbjct: 360 VDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTT--CSSCTCS---- 413
Query: 305 CEPKGKFFYCSAVET-STCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSV 363
G + C + TC V G H T+D L+ G C+Y+L+++C +S F+V
Sbjct: 414 ----GGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSS----FTV 465
Query: 364 EAKNEHRRGSAV---SWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKI 420
A E R+ + +K +++ ++G I + G V +N + T LP L + +
Sbjct: 466 LA--ELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLP--LSAANITL 521
Query: 421 YQ-SGISTAVETDFGL--LVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDG 477
+ S V+T GL LV + + ++ CGLCGN+N+N DDF G
Sbjct: 522 FTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSG 581
Query: 478 RPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWEC 537
+ +W+ A + D C+ + E + +C L + C
Sbjct: 582 VVEATGAAFANTWKAQAACANARNSFEDPCS---LSVENENYARHWCSRLTDPNSAFSRC 638
Query: 538 GTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQC 597
++++P F +C++D C+ + LC A+ +Y C A G+ + DWR C
Sbjct: 639 HSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNC 698
Query: 598 PSFSHYSVCTSSCPDTCSDLT-ASRNCATPC--TEGCECNQG-FVLSTSQCVPLHKCGCD 653
P Y+ +C TC L+ A C+ +GC C G F+ CVP +C C
Sbjct: 699 PKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCY 758
Query: 654 FDGHYYTMGEFF---WATANCT---VQCL------------------CEEGG-------- 681
G GE A +CT + CL C
Sbjct: 759 AHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAEC 818
Query: 682 -------DVYCFNKTCGSGEVC---AVEDGYQGCFPKRETVCLLSQNQVLH--------- 722
DV CF+ C SG VC V DG GC + + C+ N+ +
Sbjct: 819 LRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCV--HNEATYKPGETIRVD 876
Query: 723 -------------------------------TFDGASYAFPSEFSYTLLKT-CPERPEYL 750
TFDG Y+F Y L + C + +
Sbjct: 877 CNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHG 936
Query: 751 EIDI---NKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLE 807
I N G + +++ V E+ I G + G + P+ +
Sbjct: 937 TFRIVTENIPCGTTGTTCSKAIKLFVESYEL-ILQEGTFKAVARGPGGDPPY-------K 988
Query: 808 IYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKC 867
I +E+ G + V + ++IRL Y GLCG ++ NA ++F +
Sbjct: 989 IRYMGIFLVIETHG-MAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSV 1047
Query: 868 TDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRS--RSRCGIINDPSNSSFLE 925
+ F SW + C D L A + F +S + +C I++ P +F
Sbjct: 1048 VGDALEFGNSWK-----LSPSCPDAL-APKDPCTANPFRKSWAQKQCSILHGP---TFAA 1098
Query: 926 CHGVVNVTAYYRTCL--FRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLE 983
C V+ T YY C+ C SGG+ C +VA YA AC +A + V WRT D CPL
Sbjct: 1099 CRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVS-WRTPDTCPLF 1157
Query: 984 C----PENS---HFEEC-ITCTETCETLTLGPICVDSCS-EGC--QCDEGYALLGS---Q 1029
C P H++ C C +TC + G VD EGC +C +
Sbjct: 1158 CDFYNPHGGCEWHYQPCGAPCLKTCRNPS-GHCLVDLPGLEGCYPKCPPSQPFFNEDQMK 1216
Query: 1030 CVTRSECGC 1038
CV ++CGC
Sbjct: 1217 CV--AQCGC 1223
Score = 162 bits (409), Expect = 4e-39
Identities = 159/679 (23%), Positives = 251/679 (36%), Gaps = 96/679 (14%)
Query: 1100 CIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVK 1159
C G HY TFDG F F C + S ++ F V + L
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVF----SEHCRAAYEDFNVQLRR-----GLVGSRP 127
Query: 1160 QVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVY 1219
V V ++ A +VL+N +R LP + + + G ++ V L ++
Sbjct: 128 VVTRVVIKAQGLVLEASNGSVLINGQREELPYS--RTGLLVEQSGDYIKVSIRLVLTFLW 185
Query: 1220 DWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQV 1279
+ + + + N T GLCG +NG P + NEF + R T Q
Sbjct: 186 NGEDSALLELDPKYANQTCGLCGDFNGLP-------------AFNEF-YAHNARLTPLQF 231
Query: 1280 G-----------CGDRCP----SCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFY 1324
G C D P +C EG L AF++CH+ V+ T +
Sbjct: 232 GNLQKLDGPTEQCPDPLPLPAGNCTDEEGICHRTLL-------GPAFAECHALVDSTAYL 284
Query: 1325 KNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSV 1384
C D C C+ Y+ C G WR C TCP N ++ C S
Sbjct: 285 AACAQDLC---RCPTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSP 341
Query: 1385 CQPRCAAIRLKSDCSHYCVEGCHCDAGYV------LNGKSCILPHSCGCYSDGKYYEPKQ 1438
C C+ + C +CV+GC C G + C+ C C G+ Y P
Sbjct: 342 CTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGT 401
Query: 1439 LFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTF 1498
F N+ C+ C C + QC C C GG T+
Sbjct: 402 SF-NTTCSS-CTC-SGGLWQCQDLPCPGT-------------------CSVQGGAHISTY 439
Query: 1499 DGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWS-APNLTIISPVYFYIN--EEQIL 1555
D +C++VLS C D SF ++ K N + V ++ + I
Sbjct: 440 DEKLYDLHGDCSYVLSKKCA---DSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIR 496
Query: 1556 INDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISI--SER 1613
+ V +N +P T S F+V+ T +Q+ ++++ +
Sbjct: 497 VQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPA 556
Query: 1614 LQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQY 1673
Q ++CGLCGNFN + DD+ L G + A +WK +C + + +
Sbjct: 557 HQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQA--------ACANAR-NSF 607
Query: 1674 AAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQ-LCG 1732
C + +C +LTD F C+ +++P PF+ +C D C + LC
Sbjct: 608 EDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCA 667
Query: 1733 SLAAYGEACRSFGILSTEW 1751
+L++Y AC + G+ ++W
Sbjct: 668 ALSSYVHACAAKGVQLSDW 686
Score = 134 bits (337), Expect = 1e-30
Identities = 123/482 (25%), Positives = 191/482 (39%), Gaps = 66/482 (13%)
Query: 982 LECPENSHFEECITCTETCETLTLGPICVDS-CSEGCQCDEGYALLGSQ-CVTRSECGCN 1039
L+C +S C +C TL +G C + C GC C G GS C+ +C C
Sbjct: 804 LDCSNSSAGTPGAECLRSCHTLDVG--CFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCV 861
Query: 1040 FEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTD-A 1098
H AT Y G RV C T C++ + C R
Sbjct: 862 ---HNEAT--------------YKPGETIRVDCNTCTCRNRRW--------ECSHRLCLG 896
Query: 1099 SCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWV 1158
+C+ G GH++TFDG + F+ SC IL ++ + F + +N +
Sbjct: 897 TCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNT-THGTFRIVTENIPCGTTGTTCS 955
Query: 1159 KQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVV 1218
K + + V Y +++ V G I G +V+ET G+ V
Sbjct: 956 KAIKLFVESYELILQEGTFKAVARGPG--------GDPPYKIRYMGIFLVIET-HGMAVS 1006
Query: 1219 YDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQ 1278
+D KT + I + + + GLCG ++ N +D + EFG SW K C
Sbjct: 1007 WDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSW-KLSPSCP 1065
Query: 1279 VGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCI--DGG 1336
+ P A S Q+ CS++ F+ C S+V+ T +Y+ C+ D+C GG
Sbjct: 1066 DALAPKDPCTANPFRKSWAQKQCSIL--HGPTFAACRSQVDSTKYYEACVNDACACDSGG 1123
Query: 1337 AVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKS 1396
+ C+ + YA C G+ V+ WR +C + C + + C QP
Sbjct: 1124 DCECFCTAVAAYAQACHDAGLCVS-WRTPDTCPLFCDFYNPHGGCEWHYQP--------- 1173
Query: 1397 DCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSD---CTRRCRCFR 1453
C C++ C +G+ L LP GCY P Q F+N D C +C C+
Sbjct: 1174 -CGAPCLKTCRNPSGHCL----VDLPGLEGCYPK---CPPSQPFFNEDQMKCVAQCGCYD 1225
Query: 1454 RN 1455
++
Sbjct: 1226 KD 1227
Score = 131 bits (329), Expect = 8e-30
Identities = 109/397 (27%), Positives = 170/397 (42%), Gaps = 44/397 (11%)
Query: 305 CEPKGKFFYCS-AVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQ-CLQTSSLPFFS 362
C + + + CS + TCV +G+ H+ TFDG + F+GSC Y+LA+ C ++ F
Sbjct: 880 CTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFR 939
Query: 363 VEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQ 422
+ +N + + K + + V Y++++ +G++ V KI
Sbjct: 940 IVTENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVARGPGGDP--------PYKIRY 991
Query: 423 SGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMS 482
GI +ET G+ V++D + I + Y CGLCGN++ N ++DF
Sbjct: 992 MGIFLVIET-HGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGD 1050
Query: 483 VLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALY---FGSDYCGFLNKTDGPLW-ECG 538
L+ G S WK C D D T + + C L+ GP + C
Sbjct: 1051 ALEFGNS-------WKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILH---GPTFAACR 1100
Query: 539 TVVDPTAFVHSCVYDLCSVRDNG--TLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQ 596
+ VD T + +CV D C+ G C A+ AYA C G+ + WRT C +
Sbjct: 1101 SQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCV-SWRTPDTC--PLF 1157
Query: 597 CPSFS-------HYSVCTSSCPDTCSDLTASRNCATPCTEGC--EC--NQGFVLSTSQCV 645
C ++ HY C + C TC + + P EGC +C +Q F + Q
Sbjct: 1158 CDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPF-FNEDQMK 1216
Query: 646 PLHKCGC-DFDGHYYTMGEFFWATANCTVQCLCEEGG 681
+ +CGC D DG+YY +G NC C C G
Sbjct: 1217 CVAQCGCYDKDGNYYDVGARVPTAENCQ-SCNCTPSG 1252
Score = 117 bits (292), Expect = 2e-25
Identities = 128/469 (27%), Positives = 196/469 (41%), Gaps = 54/469 (11%)
Query: 256 PANGCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCS---------PYEVCE 306
PA GC + LR+ W NCTV RC+ N + + P +V +
Sbjct: 5006 PAPGCDNAIP-LRQVNETWTLENCTV-ARCVGDNRVVLLDPKPVANVTCVNKHLPIKVSD 5063
Query: 307 PKGK--FFY-CSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSV 363
P F Y C + C ++G HY TFDG + F+G+C Y+L R+ + S+
Sbjct: 5064 PSQPCDFHYECECI----CSMWGGSHYSTFDGTSYTFRGNCTYVLMREI--HARFGNLSL 5117
Query: 364 EAKNEHRRGSAVSWV----KELSVEVNGYKILIPKGS-YGRVKVNDLVTSLPVTLDLGTV 418
N + SA + + LS+ I++ +G+ + L +PV+
Sbjct: 5118 YLDNHYCTASATAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKN 5177
Query: 419 KIYQSGI-STAVETDF---GLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLR 474
+ S + +T + D G+ VTF+GQ + + + N+T G CG N DD L+
Sbjct: 5178 GVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQ 5237
Query: 475 PDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGS----------DYC 524
DG A S D+ ++W V D + D GC A+ A S C
Sbjct: 5238 RDGTTAASCKDMAKTWLV--PDSRKD-GCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLC 5294
Query: 525 GFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGD 584
+ EC +V P F ++C+ D C R + CQ+++AYA +C+A G+ D
Sbjct: 5295 DLM--LSQVFAECHNLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAELCRARGV-CSD 5349
Query: 585 WRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQC 644
WR TG + + CP Y C P TC+ S EGC C + +L +
Sbjct: 5350 WRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQ-LEGMAEGCFCPEDQILFNAHM 5408
Query: 645 -VPLHKCGC-DFDGHYYTMGEFFWATANCTVQCLCEEGG-DVYCFNKTC 690
+ + C C DG GE + +NC C+C+EG V C C
Sbjct: 5409 GICVQACPCVGPDGFPKFPGERW--VSNCQ-SCVCDEGSVSVQCKPLPC 5454
Score = 105 bits (263), Expect = 4e-22
Identities = 99/412 (24%), Positives = 164/412 (39%), Gaps = 64/412 (15%)
Query: 1092 CQARTDASCIVSGYG--HYLTFDGFPFDFQTSCPLIL-------------------CTTG 1130
C + CI S +G HY TFDG + F+ +C +L CT
Sbjct: 5068 CDFHYECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTAS 5127
Query: 1131 SRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLP 1190
+ ++ P+ +L++ K +D+ + ++H + +L + +P
Sbjct: 5128 ATAAAARCPR------------ALSIHYKSMDIVLT--VTMVHGKEEGLILFDQ----IP 5169
Query: 1191 LKLGQGK----INIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNG 1246
+ G K +++ V G+ V ++ + F + N+T G CG
Sbjct: 5170 VSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTN 5229
Query: 1247 NPDDDLEMPMGLLASSVNEFGQSWVKRDT-----FCQVGCGDRCPSCAKVEGF-----SK 1296
N DD G A+S + ++W+ D+ + G A V
Sbjct: 5230 NQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCP 5289
Query: 1297 VQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQG 1356
Q LC L+ +Q F++CH+ V P F+ C+ D C G ++ C L+ YA C+ +G
Sbjct: 5290 PQPLCDLMLSQ--VFAECHNLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAELCRARG 5345
Query: 1357 ITVTGWRNYTS--CTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVL 1414
+ + WR T C +TCPP Y+ C + QP R +S EGC C +L
Sbjct: 5346 V-CSDWRGATGGLCDLTCPPTKVYKPCGPI-QPATCNSRNQSPQLEGMAEGCFCPEDQIL 5403
Query: 1415 -NGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNV-IQCDPRQC 1464
N I +C C + + W S+C + C C +V +QC P C
Sbjct: 5404 FNAHMGICVQACPCVGPDGFPKFPGERWVSNC-QSCVCDEGSVSVQCKPLPC 5454
Score = 92.4 bits (228), Expect = 4e-18
Identities = 88/370 (23%), Positives = 140/370 (37%), Gaps = 57/370 (15%)
Query: 1399 SHYCVEGCHCDAGYVLNGKS-CILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVI 1457
S +CV GC C G V +G CI C C + Y+P + DC C C R
Sbjct: 831 STHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETI-RVDCNT-CTCRNRRW- 887
Query: 1458 QCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLST-I 1516
+C R C C+A G G F TFDG F +C ++L+
Sbjct: 888 ECSHRLCLGT-------------------CVAYGDGHFITFDGDRYSFEGSCEYILAQDY 928
Query: 1517 C-QKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKV-NGTQVNVPFI 1574
C +F+++ T + ++ ++++ + V G + P+
Sbjct: 929 CGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVARGPGGDPPY- 987
Query: 1575 TGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYV 1634
KI FLVI+T + + ++ + I + + + +VCGLCGNF+ + +D+
Sbjct: 988 -----KIRYMGIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFA 1041
Query: 1635 TLRGKPVVSSVVLAQSWKTNGMQKRPLAP----SCNELQFSQYAAMCDNVHIQKMQGDGY 1690
T V ++ SWK + LAP + N + S C +H
Sbjct: 1042 TRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILH--------- 1092
Query: 1691 CLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQ---LCGSLAAYGEACRSFGIL 1747
F C +D +YE+C D C C ++AAY +AC G L
Sbjct: 1093 -------GPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAG-L 1144
Query: 1748 STEWIEKENC 1757
W + C
Sbjct: 1145 CVSWRTPDTC 1154
Score = 63.2 bits (152), Expect = 3e-09
Identities = 103/447 (23%), Positives = 155/447 (34%), Gaps = 50/447 (11%)
Query: 666 WATANCTV-QCLCEEG---------GDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLL 715
W NCTV +C+ + +V C NK V D Q C E C+
Sbjct: 5023 WTLENCTVARCVGDNRVVLLDPKPVANVTCVNKHLP----IKVSDPSQPCDFHYECECIC 5078
Query: 716 SQNQVLH--TFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILV 773
S H TFDG SY F +Y L++ R L + ++ A
Sbjct: 5079 SMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAARCPRA 5138
Query: 774 ADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLL 833
K I + ++G+E L F + +KN V G T++ DI L
Sbjct: 5139 LSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGF-SKNGVLVSVLGTTTMRV-DIPAL 5196
Query: 834 YIRLS------------TTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTF 881
+ ++ + + N T G CG N D+ +G + ++W
Sbjct: 5197 GVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVP 5256
Query: 882 EEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPS-----NSSFLECHGVVNVTAYY 936
+ +G C S + + P + F ECH +V ++
Sbjct: 5257 DSRKDG-CWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFF 5315
Query: 937 RTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWR--TYDFCPLECPENSHFEECI 994
C+ C+ G C S+ YA C+ V WR T C L CP ++ C
Sbjct: 5316 NACISDHCR--GRLEVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCG 5372
Query: 995 TC-TETCETLTLGPICVDSCSEGCQCDEGYALLGSQ---CVTRSECGCNFEGHQLATNET 1050
TC + P ++ +EGC C E L + CV C +G E
Sbjct: 5373 PIQPATCNSRNQSP-QLEGMAEGCFCPEDQILFNAHMGICVQACPC-VGPDGFPKFPGER 5430
Query: 1051 FWVDLDCQIFCYCSGTDNRVHCETIPC 1077
WV +CQ C C V C+ +PC
Sbjct: 5431 -WVS-NCQ-SCVCDEGSVSVQCKPLPC 5454
Score = 53.9 bits (128), Expect = 2e-06
Identities = 69/285 (24%), Positives = 109/285 (38%), Gaps = 32/285 (11%)
Query: 1487 CLAAGGGVFRTFDGAFLRFPANCAFVLST-ICQKLPDISFQLIINFDKWSAPNLTIISPV 1545
C GG + TFDG F NC +VL I + ++S L ++ SA P
Sbjct: 5078 CSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAARCPR 5137
Query: 1546 YFYIN----------------EEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLV 1589
I+ EE +++ D+ V +G N G+ + + V
Sbjct: 5138 ALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVS-SGFSKN-----GVLVSVLGTTTMRV 5191
Query: 1590 IDTSPDIQIYYNGFNVIKISISERL-QNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLA 1648
+ + + +NG V + + L N G CG + DD + G S +A
Sbjct: 5192 DIPALGVSVTFNG-QVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMA 5250
Query: 1649 QSWKTNGMQKRPL-APSCNELQFSQYAAMCDNVHIQKMQGDGYC-LKLTDMKGFFQPCYG 1706
++W +K AP+ S A + C L L+ + F C+
Sbjct: 5251 KTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQV---FAECHN 5307
Query: 1707 LLDPLPFYESCYLDGCYSHKKFQLCGSLAAYGEACRSFGILSTEW 1751
L+ P PF+ +C D C + C SL AY E CR+ G+ S +W
Sbjct: 5308 LVPPGPFFNACISDHCRGRLEVP-CQSLEAYAELCRARGVCS-DW 5350
>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
Length = 2013
Score = 231 bits (589), Expect = 6e-60
Identities = 195/733 (26%), Positives = 300/733 (40%), Gaps = 80/733 (10%)
Query: 723 TFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGG 782
TFDG + FP +Y + C E I + + + A P R L +K+ G
Sbjct: 91 TFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLSRVL--------MKVDG 142
Query: 783 I----GASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLS 838
+ V +NG V LPF SG L I ++ + T VE++ + + ++ L + L
Sbjct: 143 VVIQLTKGSVLVNGHPVLLPFSQ-SGVL-IQQSSSYTKVEARLGLVLMWNHDDSLLLELD 200
Query: 839 TTYFNCTGGLCGFYNAN-ASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACN 897
T Y N T GLCG +N E N K T L+ E C + + C+
Sbjct: 201 TKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDDPTEQCQDPVPEPPRNCS 260
Query: 898 NDSELLKFYRSRSRCGIINDPSNSS-FLECHGVVNVTAYYRTCLFRLCQSGGNE--SELC 954
GI + + F C +V+V +Y C LC + S +C
Sbjct: 261 TGF------------GICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVC 308
Query: 955 DSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECIT-CTETCETLTLGPICVDSC 1013
++A Y+ C +A WR DFCP +CP N + EC + C +TC C D C
Sbjct: 309 HTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHC 368
Query: 1014 SEGCQCDEGYAL--LGSQ-CVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRV 1070
GC C EG L +G CV S+C C + G A T+ DC C CSG R
Sbjct: 369 VAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTCSG--GRW 423
Query: 1071 HCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTG 1130
C+ +PC +C V G H+ TFDG + C +L
Sbjct: 424 SCQEVPCP-------------------GTCSVLGGAHFSTFDGKQYTVHGDCSYVL---- 460
Query: 1131 SRP-SSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYL 1189
++P S +F + D L K V +++ G V+ V +N ++Y
Sbjct: 461 TKPCDSSAFTVLAELRRCGLTDSETCL--KSVTLSLDGVQTVVVIKASGEVFLN--QIYT 516
Query: 1190 PLKLGQGKINIFSFG-FHVVVETDFGLKV----VYDWKTFLSITVPRSMQNSTYGLCGRY 1244
L + + IF F ++ +T GL++ V + F+ + ++ T GLCG +
Sbjct: 517 QLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAP--KLRGQTCGLCGNF 574
Query: 1245 NGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLI 1304
N DD G++ ++ F ++ + + P VE Q CS +
Sbjct: 575 NSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQL 634
Query: 1305 PNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRN 1364
+ + F +CH+ V P +Y NC+FD+C + C+ L +Y C +G+ + GWR+
Sbjct: 635 TDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRD 694
Query: 1365 --YTSCTVTCPPNSHYESCVSVCQPRCAAIR---LKSDCSHYCVEGCHCDAGYVLNGK-S 1418
T TCP + Y VS CQP C ++ + V+GC C G L+
Sbjct: 695 GVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGK 754
Query: 1419 CILPHSCGCYSDG 1431
C+ +C CY G
Sbjct: 755 CVQASNCPCYHRG 767
Score = 229 bits (583), Expect = 3e-59
Identities = 205/779 (26%), Positives = 318/779 (40%), Gaps = 95/779 (12%)
Query: 322 CVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKEL 381
C +G HY TFDG +F F G C Y+ + C ++ F+++ + SA + +
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHC--GAAYEDFNIQLRRSQE--SAAPTLSRV 136
Query: 382 SVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGT--VKIYQSGISTAVETDFGLLVTF 439
++V+G I + KGS LV PV L V I QS T VE GL++ +
Sbjct: 137 LMKVDGVVIQLTKGSV-------LVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMW 189
Query: 440 DGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKC 499
+ + + Y N TCGLCG++N P+ L ++ ++ G ++ +C
Sbjct: 190 NHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTK-LTPMEFGNLQKMDDPTEQC 248
Query: 500 DSGCVD---NCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCS 556
+ NC+ E L G + G C +VD +++ +C DLC
Sbjct: 249 QDPVPEPPRNCSTGFGICEELLHGQLFSG-----------CVALVDVGSYLEACRQDLCF 297
Query: 557 VRDNGTL--LCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTC 614
D L +C + Y+ C G DWR C +CP+ Y C S C DTC
Sbjct: 298 CEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQ--KCPNNMQYHECRSPCADTC 355
Query: 615 SDLTASRNCATPCTEGCECNQGFVL---STSQCVPLHKCGCDFDGHYYTMGEFFWATANC 671
S+ SR C C GC C +G VL + CVP+ KC C ++G Y G + + +C
Sbjct: 356 SNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDC 413
Query: 672 TVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAF 731
T C C GG C C C+V G TFDG Y
Sbjct: 414 T-NCTC-SGGRWSCQEVPCPG--TCSVLGGAH-----------------FSTFDGKQYTV 452
Query: 732 PSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVKLN 791
+ SY L K C + ++ + L+ + + + + + + EV LN
Sbjct: 453 HGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLN 512
Query: 792 GQEVELP-------FFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNC 844
+LP F PS I + + + V T+Q L+++L+
Sbjct: 513 QIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQ------LFMQLAPKLRGQ 566
Query: 845 TGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLK 904
T GLCG +N+ +D+F +G A F ++ T + C C+ E K
Sbjct: 567 TCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT-QAACPNIRNSFEDPCSLSVENEK 625
Query: 905 FYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASAC 964
+ ++ C + D ++ F CH V YY C+F C +E LC +++ Y AC
Sbjct: 626 Y--AQHWCSQLTD-ADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHAC 682
Query: 965 KNADVEVGPWRTYDFCP---LECPENSHFEECI-TCTETCETLTLGPICVDSCS------ 1014
V++G WR C CP++ + + TC TC +L+ G I +CS
Sbjct: 683 AAKGVQLGGWRD-GVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDI---TCSVGFIPV 738
Query: 1015 EGCQCDEGYALLGS-QCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHC 1072
+GC C +G L + +CV S C C G + E+ D C C T ++ C
Sbjct: 739 DGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVH---DSGAICTC--THGKLSC 792
Score = 198 bits (503), Expect = 5e-50
Identities = 236/978 (24%), Positives = 359/978 (36%), Gaps = 177/978 (18%)
Query: 264 GQFLRRGEVFWDDLNCT-----VKCRCLDFNNEIYCQEASCSP-YEVCEPKGKFFYCSAV 317
G F G V DD+ T KC C+ +N Y A+ S C G + C V
Sbjct: 371 GCFCPEGTVL-DDIGQTGCVPVSKCACV-YNGAAYAPGATYSTDCTNCTCSGGRWSCQEV 428
Query: 318 ET-STCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRR---GS 373
TC V G H+ TFDG + G C+Y+L + C ++ F+V A E RR
Sbjct: 429 PCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSA----FTVLA--ELRRCGLTD 482
Query: 374 AVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQ-SGISTAVETD 432
+ + +K +++ ++G + ++ + G V +N + T LP++ V I++ S +T
Sbjct: 483 SETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISA--ANVTIFRPSTFFIIAQTS 540
Query: 433 FGLLVTFD--GQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESW 490
GL + + + TCGLCGN+N DDF G + ++
Sbjct: 541 LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF 600
Query: 491 RVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSC 550
+ A + D C+ + E + +C L DGP C V P + +C
Sbjct: 601 KTQAACPNIRNSFEDPCS---LSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNC 657
Query: 551 VYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSC 610
++D C+ + LC A+ +Y C A G+ +G WR CP Y S+C
Sbjct: 658 MFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTC 717
Query: 611 PDTCSDLT-ASRNCATPC--TEGCECNQG-FVLSTSQCVPLHKCGCDFDGHYYTMGEFF- 665
TC L+ C+ +GC C +G F+ T +CV C C G GE
Sbjct: 718 QPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVH 777
Query: 666 --WATANCTVQCLCEEGG-----------------------------------DVYCFNK 688
A CT L GG D+ C++
Sbjct: 778 DSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSP 837
Query: 689 TCGSGEVC---AVEDGYQGCFPKRETVCLLSQ-----NQVLH------------------ 722
C G VC V DG GC + C+ ++ Q +
Sbjct: 838 QCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDD 897
Query: 723 ---------------TFDGASYAFPSEFSYTLLKT-C----PERPEYLEIDINKKKPDAG 762
TFDG SY+F + YTL++ C + + + N G
Sbjct: 898 PCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTG 957
Query: 763 PAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGV 822
+ ++I + E+K+ G EV + E+P+ T+ G+
Sbjct: 958 TTCSKAIKIFLGGFELKLSH-GKVEVIGTDESQEVPY----------------TIRQMGI 1000
Query: 823 VTVQYSDIGL---------LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAV 873
V +DIGL ++I LS + GLCG ++ A ++F + ++
Sbjct: 1001 YLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLE 1060
Query: 874 FLESWTTFEEICNGECGDLLKACNNDSELLKFYRS--RSRCGIINDPSNSSFLECHGVVN 931
F SW + C D L A + F +S + +C I++ P +F CH V
Sbjct: 1061 FGNSWK-----LSPSCPDAL-APKDPCTANPFRKSWAQKQCSILHGP---TFAACHAHVE 1111
Query: 932 VTAYYRTCL--FRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLEC----P 985
YY C+ C SGG+ C +VA YA AC + V WRT CPL C P
Sbjct: 1112 PARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVS-WRTPSICPLFCDYYNP 1170
Query: 986 ENS---HFEEC-ITCTETCETLTLGPICVDSCS-EGC--QCDEGYALLGS---QCVTRSE 1035
E H++ C + C TC G D EGC +C + QCV
Sbjct: 1171 EGQCEWHYQPCGVPCLRTCRN-PRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCP 1229
Query: 1036 C-----GCNFEGHQLATNETFWVDLDCQIFCYCS--GTDNRVHCETIPCKDDEYCMEEGG 1088
C+ G D +CQ C C+ G + E C + G
Sbjct: 1230 TPPLPPRCHVHGKSYRPGAVVPSDKNCQ-SCLCTERGVECTYKAEACVCTYNGQRFHPGD 1288
Query: 1089 LYYCQARTDASCIVSGYG 1106
+ Y CI + G
Sbjct: 1289 VIYHTTDGTGGCISARCG 1306
Score = 173 bits (438), Expect = 2e-42
Identities = 165/671 (24%), Positives = 257/671 (38%), Gaps = 78/671 (11%)
Query: 1100 CIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKN--EDRDPSLALW 1157
C G HY TFDG F F C + S ++ F + + E P+L+
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVF----SEHCGAAYEDFNIQLRRSQESAAPTLSRV 136
Query: 1158 VKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKV 1217
+ +VD V + K +VLVN + LP Q + I + VE GL +
Sbjct: 137 LMKVDGVVIQLT-------KGSVLVNGHPVLLPFS--QSGVLIQQSSSYTKVEARLGLVL 187
Query: 1218 VYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVN----EFGQSWVKR 1273
+++ L + + N T GLCG +NG P + LL+ + EFG
Sbjct: 188 MWNHDDSLLLELDTKYANKTCGLCGDFNGMP-----VVSELLSHNTKLTPMEFGNLQKMD 242
Query: 1274 DTFCQVGCGDRCPSCAK--VEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDS 1331
D Q C D P + GF ++L FS C + V+ + + C D
Sbjct: 243 DPTEQ--CQDPVPEPPRNCSTGFGICEELL-----HGQLFSGCVALVDVGSYLEACRQDL 295
Query: 1332 CI--DGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRC 1389
C D + C L Y+ C G WR C CP N Y C S C C
Sbjct: 296 CFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTC 355
Query: 1390 AAIRLKSDCSHYCVEGCHCDAGYVLNG---KSCILPHSCGCYSDGKYYEPKQLFWNSDCT 1446
+ C +CV GC C G VL+ C+ C C +G Y P + ++DCT
Sbjct: 356 SNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY-STDCT 414
Query: 1447 RRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFP 1506
C C C C C GG F TFDG
Sbjct: 415 N-CTCSGGRW-SCQEVPCPGT-------------------CSVLGGAHFSTFDGKQYTVH 453
Query: 1507 ANCAFVLSTICQKLPDISFQLIINFDKWSAPNL-TIISPVYFYINEEQ--ILINDRNTVK 1563
+C++VL+ C +F ++ + + T + V ++ Q ++I V
Sbjct: 454 GDCSYVLTKPCDSS---AFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVF 510
Query: 1564 VNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKI--SISERLQNKVCGL 1621
+N +P T S F++ TS +Q+ +++ ++ +L+ + CGL
Sbjct: 511 LNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGL 570
Query: 1622 CGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVH 1681
CGNFN DD+ TL G ++ ++KT +C ++ + + C
Sbjct: 571 CGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQA--------ACPNIR-NSFEDPCSLSV 621
Query: 1682 IQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQ-LCGSLAAYGEA 1740
+ +C +LTD G F C+ + P +Y +C D C + LC +L++Y A
Sbjct: 622 ENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHA 681
Query: 1741 CRSFGILSTEW 1751
C + G+ W
Sbjct: 682 CAAKGVQLGGW 692
Score = 140 bits (354), Expect = 1e-32
Identities = 135/538 (25%), Positives = 204/538 (37%), Gaps = 79/538 (14%)
Query: 996 CTETCETLTLGPICVD-SCSEGCQCDEGYALLGSQ-CVTRSECGCNFEGHQLATNETFWV 1053
C ++C TL + C C GC C +G G C+T +C C NE
Sbjct: 823 CQKSCHTLDM--TCYSPQCVPGCVCPDGLVADGEGGCITAEDCPC-------VHNEA--- 870
Query: 1054 DLDCQIFCYCSGTDNRVHCETIPCKDDEY-CMEEGGLYYCQARTDASCIVSGYGHYLTFD 1112
Y +G RV C T C + C ++ L A+C V G GHYLTFD
Sbjct: 871 -------SYRAGQTIRVGCNTCTCDSRMWRCTDDPCL--------ATCAVYGDGHYLTFD 915
Query: 1113 GFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVI 1172
G + F C L + F V +N + K + + + G+ + +
Sbjct: 916 GQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKL 975
Query: 1173 HRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRS 1232
K V+ E +P + Q G ++VV+TD GL +++D KT + I +
Sbjct: 976 SHG-KVEVIGTDESQEVPYTIRQ-------MGIYLVVDTDIGLVLLWDKKTSIFINLSPE 1027
Query: 1233 MQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGCGDRCPSCAKVE 1292
+ GLCG ++ +D + V EFG SW K C + P A
Sbjct: 1028 FKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSW-KLSPSCPDALAPKDPCTANPF 1086
Query: 1293 GFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCI--DGGAVQTACSWLQNYAS 1350
S Q+ CS++ F+ CH+ V P +Y+ C+ D+C GG + C+ + YA
Sbjct: 1087 RKSWAQKQCSIL--HGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQ 1144
Query: 1351 TCQTQGITVTGWRNYTSCTVTCPPNS-------HYESCVSVCQPRCAAIRLKSDCSH--Y 1401
C G+ V+ WR + C + C + HY+ C C C R DC +
Sbjct: 1145 ACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPR--GDCLRDVW 1201
Query: 1402 CVEGCH--CDAGYVL---NGKSCIL-----PHSCGCYSDGKYYEPKQLFWNSDCTRRCRC 1451
+EGC+ C + + C+ P C+ GK Y P + + + C C
Sbjct: 1202 GLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLC 1261
Query: 1452 FRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANC 1509
R V EC + C T G ++ T DG A C
Sbjct: 1262 TERGV------------ECTYK--AEACVCTYNGQRFHPGDVIYHTTDGTGGCISARC 1305
Score = 95.1 bits (235), Expect = 6e-19
Identities = 97/387 (25%), Positives = 150/387 (38%), Gaps = 62/387 (16%)
Query: 1385 CQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKS-CILPHSCGCYSDGKYYEPKQLFWNS 1443
CQ C + + S CV GC C G V +G+ CI C C + Y Q
Sbjct: 823 CQKSCHTLDMTC-YSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQ----- 876
Query: 1444 DCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFL 1503
T R C N CD R + ++ C +T C G G + TFDG
Sbjct: 877 --TIRVGC---NTCTCDSRMWRCTDD--------PCLAT----CAVYGDGHYLTFDGQSY 919
Query: 1504 RFPANCAFVL-STIC--QKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRN 1560
F +C + L C + SF+++ T + ++ ++ ++
Sbjct: 920 SFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLS-HG 978
Query: 1561 TVKVNGTQVN--VPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKV 1618
V+V GT + VP+ I +LV+DT + + ++ I I++S + +V
Sbjct: 979 KVEVIGTDESQEVPYT------IRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRV 1032
Query: 1619 CGLCGNFNGDLTDDYVTLRGKPVVSSVV-LAQSWKTNGMQKRPLAP----SCNELQFSQY 1673
CGLCGNF+ +D+ T R + VV V+ SWK + LAP + N + S
Sbjct: 1033 CGLCGNFDDIAVNDFAT-RSRSVVGDVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWA 1091
Query: 1674 AAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQ---L 1730
C +H F C+ ++P +YE+C D C
Sbjct: 1092 QKQCSILH----------------GPTFAACHAHVEPARYYEACVNDACACDSGGDCECF 1135
Query: 1731 CGSLAAYGEACRSFGILSTEWIEKENC 1757
C ++AAY +AC G L W C
Sbjct: 1136 CTAVAAYAQACHEVG-LCVSWRTPSIC 1161
>gi|56550049 uromodulin precursor [Homo sapiens]
Length = 640
Score = 214 bits (546), Expect = 6e-55
Identities = 116/334 (34%), Positives = 186/334 (55%), Gaps = 18/334 (5%)
Query: 1753 EKENCSGVVEDPCVGADCPNRTCELGNGRELCGCIEPPPYGNNSHDIIDAEVTCKAAQME 1812
+ + G E+ + DC + NGR C C + + +++ + C A M+
Sbjct: 289 DPSSVEGTCEECSIDEDCKSN-----NGRWHCQCKQD--FNITDISLLEHRLECGANDMK 341
Query: 1813 VSISKCKLFQLGFEREGVRINDRQCTGI---EGEDFISFQINNTKGNCGNIVQSNGTHIM 1869
VS+ KC+L LGF++ + ++D +C+G + D++S G CG ++ N TH
Sbjct: 342 VSLGKCQLKSLGFDKVFMYLSDSRCSGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHAT 401
Query: 1870 YKNTLWIESANNTGNIITRDRTINVEFSCAYELDIKISLDSVVKPMLSVINLTVPTQEGS 1929
Y NTL++ II RD I + F+C+Y LD+K+SL + ++PM+S +N+ V G
Sbjct: 402 YSNTLYLAD-----EIIIRDLNIKINFACSYPLDMKVSLKTALQPMVSALNIRVGGT-GM 455
Query: 1930 FITKMALYKNASYKHPYRQGEVVLTTRDVLYVGVFVVGADATHLILTLNKCYATPTRDSN 1989
F +MAL++ SY PY+ V L+T LYVG + G D + L + CYATP+ ++
Sbjct: 456 FTVRMALFQTPSYTQPYQGSSVTLSTEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNAT 515
Query: 1990 DKLRYFIIEGGCQNLKDNTIGIEENAVSLTCRFHVTVFKFIGDYDEVHLHCAVSLCDSEK 2049
D L+YFII+ C + +D+TI + EN S RF V +F+F G+YD V+LHC V LCD+
Sbjct: 516 DPLKYFIIQDRCPHTRDSTIQVVENGESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMN 575
Query: 2050 YSCKITCPHNSRIATDYTKEPKEQIISVGPIRRK 2083
CK TC +R + + + +++++GPI RK
Sbjct: 576 EKCKPTC-SGTRFRSGSVID-QSRVLNLGPITRK 607
>gi|59850812 uromodulin precursor [Homo sapiens]
Length = 640
Score = 214 bits (546), Expect = 6e-55
Identities = 116/334 (34%), Positives = 186/334 (55%), Gaps = 18/334 (5%)
Query: 1753 EKENCSGVVEDPCVGADCPNRTCELGNGRELCGCIEPPPYGNNSHDIIDAEVTCKAAQME 1812
+ + G E+ + DC + NGR C C + + +++ + C A M+
Sbjct: 289 DPSSVEGTCEECSIDEDCKSN-----NGRWHCQCKQD--FNITDISLLEHRLECGANDMK 341
Query: 1813 VSISKCKLFQLGFEREGVRINDRQCTGI---EGEDFISFQINNTKGNCGNIVQSNGTHIM 1869
VS+ KC+L LGF++ + ++D +C+G + D++S G CG ++ N TH
Sbjct: 342 VSLGKCQLKSLGFDKVFMYLSDSRCSGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHAT 401
Query: 1870 YKNTLWIESANNTGNIITRDRTINVEFSCAYELDIKISLDSVVKPMLSVINLTVPTQEGS 1929
Y NTL++ II RD I + F+C+Y LD+K+SL + ++PM+S +N+ V G
Sbjct: 402 YSNTLYLAD-----EIIIRDLNIKINFACSYPLDMKVSLKTALQPMVSALNIRVGGT-GM 455
Query: 1930 FITKMALYKNASYKHPYRQGEVVLTTRDVLYVGVFVVGADATHLILTLNKCYATPTRDSN 1989
F +MAL++ SY PY+ V L+T LYVG + G D + L + CYATP+ ++
Sbjct: 456 FTVRMALFQTPSYTQPYQGSSVTLSTEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNAT 515
Query: 1990 DKLRYFIIEGGCQNLKDNTIGIEENAVSLTCRFHVTVFKFIGDYDEVHLHCAVSLCDSEK 2049
D L+YFII+ C + +D+TI + EN S RF V +F+F G+YD V+LHC V LCD+
Sbjct: 516 DPLKYFIIQDRCPHTRDSTIQVVENGESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMN 575
Query: 2050 YSCKITCPHNSRIATDYTKEPKEQIISVGPIRRK 2083
CK TC +R + + + +++++GPI RK
Sbjct: 576 EKCKPTC-SGTRFRSGSVID-QSRVLNLGPITRK 607
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 210 bits (535), Expect = 1e-53
Identities = 211/794 (26%), Positives = 310/794 (39%), Gaps = 85/794 (10%)
Query: 319 TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWV 378
++TC + HY TFDG +HF G C YLLA T ++ + + V+
Sbjct: 192 SATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQRVTMG 251
Query: 379 KELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVT 438
E ++LI G+ V V + + L + + G + G++V
Sbjct: 252 PE--------EVLIQAGN---VSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVR 300
Query: 439 FDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK 498
D SISV T GLCG YN P DDF+ P G AM G SWR+ ++
Sbjct: 301 LDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESG 360
Query: 499 C------DSGCVDNCTQCDAATEALYF---GSDYCGFLNKTDGPLWECGTVVDPTAFVHS 549
C GC D DA E + D C L +GP +C V P + +
Sbjct: 361 CLDAVEVAQGC-DPLGLIDADVEPGHLRAEAQDVCHQL--LEGPFGQCHAQVSPAEYHEA 417
Query: 550 CVYDLCSVRDNGT-------LLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSH 602
C++ C+ G+ +C +Y C I I WR C CP
Sbjct: 418 CLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHI-RWRKPGFCERL--CPGGQL 474
Query: 603 YSVCTSSCPDTCSDL--TASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYT 660
YS C S CP +C + +C C GCEC +G + + CVP C C + Y
Sbjct: 475 YSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYV 534
Query: 661 MGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAV-EDGYQGCFPKRETVCLLSQNQ 719
G+ N C+C + G +C C + CAV DG+
Sbjct: 535 PGDTVRQLCN---PCVCRD-GRWHCAQALCPA--ECAVGGDGH----------------- 571
Query: 720 VLHTFDGASYAF--PSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQE 777
TFDG SY+F Y+L++ + L I + DAG + L + + + D
Sbjct: 572 -YLTFDGRSYSFWGGQGCRYSLVQDYVK--GQLLILLEHGACDAG-SCLHAISVSLEDTH 627
Query: 778 VKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNS-TTVESKGVVTVQYSDIGLLYIR 836
+++ GA V +NGQ+V LP+ G L + R ++ + G + + YI
Sbjct: 628 IQLRDSGA--VLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVAYIT 684
Query: 837 LSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESW-TTFEEICNGECGDLLKA 895
L + + GLCG + N D+F P G ++A F + + C E LL
Sbjct: 685 LDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLSP 744
Query: 896 CNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCD 955
C S+ F + + C I++ +S F ECH +V+ +Y CL +C LC
Sbjct: 745 CTTHSQRHAF--AEAACAILH---SSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCP 799
Query: 956 SVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECI-TCTETC-ETLTLGPICVDSC 1013
++ YA C PWR CP+ CP + EC C + C + G + SC
Sbjct: 800 VLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPEDCGEL--GSC 856
Query: 1014 SEGCQCDEGYAL-LGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHC 1072
GC C G QCV S C C + A + + + C G N C
Sbjct: 857 VAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECN-RCICQERGLWN---C 912
Query: 1073 ETIPCKDDEYCMEE 1086
C +C E
Sbjct: 913 TARHCPSQAFCPRE 926
Score = 194 bits (493), Expect = 8e-49
Identities = 195/788 (24%), Positives = 296/788 (37%), Gaps = 109/788 (13%)
Query: 723 TFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGG 782
TFDG Y F +Y LL + + + + P G R+ + +EV I
Sbjct: 205 TFDGRHYHFLGRCTY-LLAGAADSTWAVHLTPGDRCPQPGHCQ----RVTMGPEEVLIQ- 258
Query: 783 IGASEVKLNGQEVELPFFHPSGKLEIYRNKN-----STTVESKGV-VTVQYSDIGLLYIR 836
A V + GQ V P G+ + + V S G+ V V+ G + I
Sbjct: 259 --AGNVSVKGQLV------PEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISIS 310
Query: 837 LSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECG-----D 891
+ + T GLCG YN D+F P G A F SW + E G +
Sbjct: 311 VDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSW----RLPGSESGCLDAVE 366
Query: 892 LLKACNN----DSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSG 947
+ + C+ D+++ + + + F +CH V+ Y+ CLF C
Sbjct: 367 VAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYCAGA 426
Query: 948 -------GNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECIT-CTET 999
G + +C + A Y AC + + WR FC CP + +C++ C +
Sbjct: 427 MAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCPGGQLYSDCVSLCPPS 485
Query: 1000 CETLTLGP--ICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDC 1057
CE + G C + C GC+C G G+ CV + C C + +
Sbjct: 486 CEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQR------------- 532
Query: 1058 QIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYC-QARTDASCIVSGYGHYLTFDGFPF 1116
Y G R C C+D G ++C QA A C V G GHYLTFDG +
Sbjct: 533 ----YVPGDTVRQLCNPCVCRD--------GRWHCAQALCPAECAVGGDGHYLTFDGRSY 580
Query: 1117 DFQTSCPLILCTTGSRPS-SDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRA 1175
F G R S + K + E + + V++ I + +
Sbjct: 581 SFWGG-------QGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLRDS 633
Query: 1176 YKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLS-ITVPRSMQ 1234
VLVN + + LP +G +++ ++ G +V++ ++ IT+
Sbjct: 634 --GAVLVNGQDVGLPW-IGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHA 690
Query: 1235 NSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGCGDRCPS------- 1287
+ GLCG + N DD P G + +S+ F + QV RCPS
Sbjct: 691 HQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKF-------QVAGKGRCPSEDSALLS 743
Query: 1288 --CAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWL 1345
+ + + C+++ ++ F +CH V+ FY CL C C L
Sbjct: 744 PCTTHSQRHAFAEAACAIL--HSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVL 801
Query: 1346 QNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHY--CV 1403
YA C +G + WRN T C V CP Y C C C DC CV
Sbjct: 802 SAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHCGK---PEDCGELGSCV 857
Query: 1404 EGCHCDAGYVLNGK-SCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPR 1462
GC+C G + + + C+ P C C + Y P +C RC C R + C R
Sbjct: 858 AGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATM-KEC-NRCICQERGLWNCTAR 915
Query: 1463 QCKSDEEC 1470
C S C
Sbjct: 916 HCPSQAFC 923
Score = 176 bits (445), Expect = 3e-43
Identities = 187/744 (25%), Positives = 276/744 (37%), Gaps = 107/744 (14%)
Query: 1087 GGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAK 1146
G L+ R A+C HY TFDG + F C +L G+ S+ + V
Sbjct: 182 GQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLA--GAADST-----WAVHLT 234
Query: 1147 NEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFH 1206
DR P + VT+ ++I V V + + +++ G
Sbjct: 235 PGDRCPQPGHCQR---VTMGPEEVLIQAG---NVSVKGQLVPEGQSWLLHGLSLQWLGDW 288
Query: 1207 VVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEF 1266
+V+ G+ V D +SI+V + T GLCG YNG P+DD P G LA F
Sbjct: 289 LVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATF 348
Query: 1267 GQSWVKRDTFCQVGCGDR------CPSCAKVEG-------FSKVQQLCSLIPNQNAAFSK 1313
G SW R + GC D C ++ ++ Q +C + F +
Sbjct: 349 GNSW--RLPGSESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQL--LEGPFGQ 404
Query: 1314 CHSKVNPTFFYKNCLFDSCIDG-------GAVQTACSWLQNYASTCQTQGITVTGWRNYT 1366
CH++V+P +++ CLF C G Q C+ +Y C + I + WR
Sbjct: 405 CHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPG 463
Query: 1367 SCTVTCPPNSHYESCVSVCQPRCAAIRL--KSDCSHYCVEGCHCDAGYVLNGKSCILPHS 1424
C CP Y CVS+C P C A+ + C CV GC C G NG C+
Sbjct: 464 FCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAH 523
Query: 1425 CGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTK- 1483
C CY + Y P D R+ C+P C R+G C
Sbjct: 524 CPCYYCRQRYVP------GDTVRQL---------CNP--------CVCRDGRWHCAQALC 560
Query: 1484 TSYCLAAGGGVFRTFDGAFLRF--PANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTI 1541
+ C G G + TFDG F C + L + QL+I + + +
Sbjct: 561 PAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQ-----DYVKGQLLILLEHGACDAGSC 615
Query: 1542 ISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYN 1601
+ + + + I + D V VNG V +P+I + + ++ P Q+ +
Sbjct: 616 LHAISVSLEDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWG 675
Query: 1602 -GFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRP 1660
V I++ R ++V GLCG F + DD++T G S A ++ G + P
Sbjct: 676 LSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCP 735
Query: 1661 ------LAPSCNELQFSQYA-AMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPF 1713
L+P Q +A A C +H FQ C+ L+D PF
Sbjct: 736 SEDSALLSPCTTHSQRHAFAEAACAILH----------------SSVFQECHRLVDKEPF 779
Query: 1714 YESCYLDGCYSHKKFQ-LCGSLAAYGEACRSFGILSTEWIEKENCSGVVED--------P 1764
Y C C LC L+AY C G S W + C + P
Sbjct: 780 YLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEG-ASPPWRNQTLCPVMCPGGQEYRECAP 838
Query: 1765 CVGADC--PNRTCELGNGRELCGC 1786
G C P ELG+ C C
Sbjct: 839 ACGQHCGKPEDCGELGSCVAGCNC 862
Score = 157 bits (398), Expect = 8e-38
Identities = 131/491 (26%), Positives = 195/491 (39%), Gaps = 50/491 (10%)
Query: 970 EVGPWR-TYDFCPLE--CPENSHFEECITCTETCETLTLGPICVDSCSEGCQCDEGYALL 1026
E G W T CP + CP + C TC++ + C ++GC C G LL
Sbjct: 906 ERGLWNCTARHCPSQAFCPRELVYAPG-ACLLTCDSPSANHSCPAGSTDGCVCPPGTVLL 964
Query: 1027 GSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEE 1086
+CV C C G N T + DC + C C G + HC
Sbjct: 965 DERCVPPDLCPCRHSGQWYLPNAT--IQEDCNV-CVCRG--RQWHCTG------------ 1007
Query: 1087 GGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAK 1146
R C SG HY+TFDG F + +C +L S F V+A+
Sbjct: 1008 -------QRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASG-------LFTVSAQ 1053
Query: 1147 NEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFH 1206
N S K + V + G V+H V VN + P +++ G
Sbjct: 1054 NLPCGASGLTCTKALAVRLEG--TVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLF 1111
Query: 1207 VVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEF 1266
+++ T GL +++D T + + + + GLCG ++G+ +DL G+L +
Sbjct: 1112 LLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELA 1171
Query: 1267 GQSWVKRDTFCQVG-CGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYK 1325
SW + G C G+++ + L P F+ CH++V P Y+
Sbjct: 1172 AHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQP----LFTLCHAEVPPQQHYE 1227
Query: 1326 NCLFDS--CIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVS 1383
CL+D+ C GG + CS + YA C G V WR+ C++ C YE+C
Sbjct: 1228 WCLYDACGCDSGGDCECLCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGP 1286
Query: 1384 VCQPRCAAIRLKS--DCSHY-CVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLF 1440
C P C + C CVEGC C G +L+G +C+ P SC C + P +
Sbjct: 1287 TCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVL 1346
Query: 1441 WNSDCTRRCRC 1451
DC C C
Sbjct: 1347 -QKDC-GNCTC 1355
Score = 139 bits (350), Expect = 3e-32
Identities = 135/529 (25%), Positives = 202/529 (38%), Gaps = 58/529 (10%)
Query: 574 VCQALGIPIGDWR-TQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCE 632
+CQ G+ W T C S CP Y+ +C TC +A+ +C T+GC
Sbjct: 903 ICQERGL----WNCTARHCPSQAFCPRELVYA--PGACLLTCDSPSANHSCPAGSTDGCV 956
Query: 633 CNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGS 692
C G VL +CVP C C G W N T+Q C
Sbjct: 957 CPPGTVLLDERCVPPDLCPCRHSGQ--------WYLPNATIQEDC--------------- 993
Query: 693 GEVCAVEDGYQGCFPKRET-VCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLE 751
VC C +R + C S TFDG ++ +P Y L++
Sbjct: 994 -NVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL----- 1047
Query: 752 IDINKKKPDAGPAWLRGLRILVADQE-VKIGGIGASEVKLNGQEVELPFFHPSGKLEIYR 810
++ + G + L + L E + + V +NG V P + L + R
Sbjct: 1048 FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRR 1107
Query: 811 NKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDN 870
+ + +T+ + + ++LS + GLCG ++ +AS++ G
Sbjct: 1108 AGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPT 1167
Query: 871 LAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVV 930
+ SW +C E GDL C ++ + +R+RCG + P F CH V
Sbjct: 1168 AELAAHSW-RLSPLC-PEPGDLPHPCTMNTHRAGW--ARARCGALLQP---LFTLCHAEV 1220
Query: 931 NVTAYYRTCLFRL--CQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENS 988
+Y CL+ C SGG+ LC ++A YA C V WR+ + C L+C
Sbjct: 1221 PPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHV-RWRSQELCSLQCEGGQ 1279
Query: 989 HFEEC-ITCTETCETLTLGP---ICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQ 1044
+E C TC TC P V +C EGC C EG L G C+ + C C + +
Sbjct: 1280 VYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNS 1339
Query: 1045 LATNETFWVD---LDCQIFCYCSGTDNRVHCETI--PCKDDEYCMEEGG 1088
D CQ + G D HCE + C + E +E G
Sbjct: 1340 FPPGSVLQKDCGNCTCQEGQWHCGGDGG-HCEELVPACAEGEALCQENG 1387
Score = 130 bits (327), Expect = 1e-29
Identities = 111/419 (26%), Positives = 172/419 (41%), Gaps = 37/419 (8%)
Query: 304 VCEPKGKFFYCSAVETS-TCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFS 362
VC +G+ ++C+ S C G PHY TFDG F + G+C YLL R+ + F+
Sbjct: 995 VCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVRE-----ASGLFT 1049
Query: 363 VEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQ 422
V A+N S ++ K L+V + G + + +G V VN + + P + + +
Sbjct: 1050 VSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGR--AVTVNGVSVTPPKVYTGPGLSLRR 1107
Query: 423 SGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMS 482
+G+ + T GL + +DG + + + GLCG+++ + +D G +
Sbjct: 1108 AGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPT 1167
Query: 483 VLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWE-CGTVV 541
SWR+ + + G D C T + CG L + PL+ C V
Sbjct: 1168 AELAAHSWRL--SPLCPEPG--DLPHPCTMNTHRAGWARARCGALLQ---PLFTLCHAEV 1220
Query: 542 DPTAFVHSCVYDLCSVRDNG--TLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPS 599
P C+YD C G LC AI YA C G + WR+Q C ++QC
Sbjct: 1221 PPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHV-RWRSQELC--SLQCEG 1277
Query: 600 FSHYSVCTSSCPDTCSDL--TASRNC-ATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDG 656
Y C +CP TC + +C C EGC C +G +L C+ C C++
Sbjct: 1278 GQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGR 1337
Query: 657 HYYTMGEFFWATANCTVQCLCEE--------GGDVYCFNKTCGSGEVCAVEDGYQGCFP 707
+ + G C C+E GG C GE E+G+ C P
Sbjct: 1338 NSFPPGSVLQKDCG---NCTCQEGQWHCGGDGGHCEELVPACAEGEALCQENGH--CVP 1391
Score = 123 bits (308), Expect = 2e-27
Identities = 120/452 (26%), Positives = 173/452 (38%), Gaps = 60/452 (13%)
Query: 272 VFWDDLNCTVKCRCLDFNNEIYCQEASC---SPYEVCEP----KGKFFYCSAVETSTCVV 324
+FW+ C C + YC++ + ++C P G++ A+ + C V
Sbjct: 511 LFWNGTLCVPAAHCPCY----YCRQRYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAV 566
Query: 325 FGEPHYHTFDGFLFHFQG--SCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKELS 382
G+ HY TFDG + F G C Y L + ++ L EH A S + +S
Sbjct: 567 GGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILL------EHGACDAGSCLHAIS 620
Query: 383 VEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDG- 441
V + I + G V VN D+G I G+S + LL+ + G
Sbjct: 621 VSLEDTHIQLRDS--GAVLVNG--------QDVGLPWIGAEGLSVRRASSAFLLLRWPGA 670
Query: 442 QHYASISVPGSYI-------NSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYH 494
Q +S P +YI + GLCG + +N DDFL P G S+ ++V
Sbjct: 671 QVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQV-A 729
Query: 495 ADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDL 554
+C S + C ++ F C L+ + EC +VD F C+ +
Sbjct: 730 GKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSS--VFQECHRLVDKEPFYLRCLAAV 787
Query: 555 CSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSC---- 610
C LC + AYA C G WR QT C V CP Y C +C
Sbjct: 788 CGCDPGSDCLCPVLSAYARRCAQEGAS-PPWRNQTLC--PVMCPGGQEYRECAPACGQHC 844
Query: 611 --PDTCSDLTASRNCATPCTEGCECNQGFVLS-TSQCVPLHKCGCDFDGHYYTMGEFFWA 667
P+ C +L + C GC C G + QCVP C C Y G A
Sbjct: 845 GKPEDCGELGS-------CVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGS---A 894
Query: 668 TANCTVQCLCEEGGDVYCFNKTCGSGEVCAVE 699
T +C+C+E G C + C S C E
Sbjct: 895 TMKECNRCICQERGLWNCTARHCPSQAFCPRE 926
Score = 105 bits (263), Expect = 4e-22
Identities = 112/451 (24%), Positives = 176/451 (39%), Gaps = 58/451 (12%)
Query: 1352 CQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAG 1411
CQ +G+ R+ S CP Y C C + C +GC C G
Sbjct: 904 CQERGLWNCTARHCPS-QAFCPRELVYAP--GACLLTCDSPSANHSCPAGSTDGCVCPPG 960
Query: 1412 YVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECA 1471
VL + C+ P C C G++Y P DC NV C RQ +
Sbjct: 961 TVLLDERCVPPDLCPCRHSGQWYLPNATI-QEDC---------NVCVCRGRQWHCTGQ-- 1008
Query: 1472 LRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINF 1531
++ C A+G + TFDG +P C ++L L +S Q +
Sbjct: 1009 ----------RRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNL--- 1055
Query: 1532 DKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFI-TGLATKIYSSEGFLVI 1590
A LT + + + + V VNG V P + TG + + FL++
Sbjct: 1056 -PCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLL 1114
Query: 1591 DTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQS 1650
T + + ++G + + +S + + +V GLCG+F+GD ++D + +G ++ + A S
Sbjct: 1115 STHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHS 1174
Query: 1651 WKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDP 1710
W+ + PL P +L C + C L ++ F C+ + P
Sbjct: 1175 WRLS-----PLCPEPGDLPHP-----CTMNTHRAGWARARCGAL--LQPLFTLCHAEVPP 1222
Query: 1711 LPFYESCYLD--GCYSHKKFQ-LCGSLAAYGEACRSFGILSTEWIEKENCS-----GVVE 1762
YE C D GC S + LC ++A Y + C G W +E CS G V
Sbjct: 1223 QQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHG-HHVRWRSQELCSLQCEGGQVY 1281
Query: 1763 DPCVGADCPNRTC-----ELGNGRELCGCIE 1788
+ C G CP TC E G ++ C+E
Sbjct: 1282 EAC-GPTCP-PTCHEQHPEPGWHCQVVACVE 1310
Score = 60.1 bits (144), Expect = 2e-08
Identities = 28/71 (39%), Positives = 40/71 (56%), Gaps = 2/71 (2%)
Query: 610 CPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATA 669
CP +C D A+R+C+ C EGC C G +L ++C+PL +C C G F
Sbjct: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSF-LLG 2693
Query: 670 NCTVQCLCEEG 680
NC+ QC+CE+G
Sbjct: 2694 NCS-QCVCEKG 2703
Score = 58.2 bits (139), Expect = 9e-08
Identities = 30/98 (30%), Positives = 39/98 (39%), Gaps = 4/98 (4%)
Query: 597 CPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDG 656
CP + C P +C++L+A R C GC C G +L + CVP C C +G
Sbjct: 3090 CPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEG 3148
Query: 657 HYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGE 694
H Y G C C G C + C GE
Sbjct: 3149 HLYPPGS---TVVRPCENCSCVSGLIANCSSWPCAEGE 3183
Score = 54.7 bits (130), Expect = 1e-06
Identities = 32/104 (30%), Positives = 42/104 (40%), Gaps = 7/104 (6%)
Query: 597 CPSFSHYSVCTSSCPDTCSDLTASRNCATP--CTEGCECNQGFVLSTSQCVPLHKCGC-D 653
CP+ C + CP CSDL C C +GC C +G + CVP+ C C D
Sbjct: 4062 CPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHCDCTD 4121
Query: 654 FDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCA 697
GH + G N C C + G + C + C CA
Sbjct: 4122 AQGHSWAPGSQHQDACN---NCSC-QAGQLSCTAQPCPPPTHCA 4161
Score = 52.4 bits (124), Expect = 5e-06
Identities = 52/195 (26%), Positives = 80/195 (41%), Gaps = 23/195 (11%)
Query: 552 YDLCSVRDNGTLL----CQAIQAYALVCQALGIPIGDWRT-----QTGCVSTVQCPSFSH 602
+ +CS GT+ C + Q C AL + R Q GC + C
Sbjct: 1759 WSVCSEPCRGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNAT-CSGELM 1817
Query: 603 YSVCTSSCPDTCSDLTASRNCAT--PC-TEGCECNQGFVL-STSQCVPLHKCGCDFDGHY 658
+ C + CP TC D++ C PC + GC C +G VL S CV +C C DG
Sbjct: 1818 FQPC-APCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGAR 1876
Query: 659 YTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQN 718
Y G+ A+C + C+C++G + C CAV+ G+ P + +
Sbjct: 1877 YWPGQRI--KADCQL-CICQDGRP-----RRCRLNPDCAVDCGWSSWSPWAKCLGPCGSQ 1928
Query: 719 QVLHTFDGASYAFPS 733
+ +F ++ PS
Sbjct: 1929 SIQWSFRSSNNPRPS 1943
Score = 52.0 bits (123), Expect = 6e-06
Identities = 36/131 (27%), Positives = 51/131 (38%), Gaps = 12/131 (9%)
Query: 954 CDSVARYASACKNADVEVGPWRTYDFCPLECPENSHF---EECIT----CTETCETLTLG 1006
C S+A + C + T C +CPEN F E+C C C T G
Sbjct: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
Query: 1007 PICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGT 1066
C C+ GC C G L + C+ RS+C C G A+ +D C C+
Sbjct: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLD-SCN---NCTCV 2971
Query: 1067 DNRVHCETIPC 1077
++ C + C
Sbjct: 2972 SGKMACTSERC 2982
Score = 49.3 bits (116), Expect = 4e-05
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 17/124 (13%)
Query: 1382 VSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW 1441
V C P C + CS +CVEGC C G +L+ C+ C C + P F
Sbjct: 2632 VPPCPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFL 2691
Query: 1442 NSDCTRRCRCFRRNVIQCDPRQC-------------KSDEECALRNGVRGCFSTKTSYCL 1488
+C+ +C C + + C P C D C +GVR F + ++
Sbjct: 2692 LGNCS-QCVC-EKGELLCQPGGCPLPCGWSAWSSWAPCDRSCG--SGVRARFRSPSNPPA 2747
Query: 1489 AAGG 1492
A GG
Sbjct: 2748 AWGG 2751
Score = 49.3 bits (116), Expect = 4e-05
Identities = 29/101 (28%), Positives = 41/101 (40%), Gaps = 4/101 (3%)
Query: 981 PLECPENSHFEECITCTETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNF 1040
P CP + + +C +C L+ +C GC C G LL + CV +C C
Sbjct: 3087 PGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAH 3146
Query: 1041 EGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDE 1081
EGH T V C+ SG +C + PC + E
Sbjct: 3147 EGHLYPPGST--VVRPCENCSCVSGL--IANCSSWPCAEGE 3183
Score = 48.9 bits (115), Expect = 5e-05
Identities = 38/120 (31%), Positives = 48/120 (40%), Gaps = 18/120 (15%)
Query: 565 CQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCA 624
C+ +A VCQAL P+ T C + + YS C CP +C DL +C
Sbjct: 3291 CEGPRAQGEVCQALPCPV------TNCTAI----EGAEYSPCGPPCPRSCDDLV---HCV 3337
Query: 625 TPCTEGCECNQGFVLSTSQ--CVPLHKCGC--DFDGHYYTMGEFFWATANCTVQCLCEEG 680
C GC C G VLS++ CV C C G + G C C C EG
Sbjct: 3338 WRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCN-HCTCLEG 3396
Score = 48.5 bits (114), Expect = 7e-05
Identities = 45/177 (25%), Positives = 62/177 (35%), Gaps = 23/177 (12%)
Query: 1336 GAVQT---ACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSV------CQ 1386
G +QT +CS L +TC + T N CT CP N + S C
Sbjct: 2848 GGIQTRGRSCSSLAPGDTTCPGPH-SQTRDCNTQPCTAQCPENMLFRSAEQCHQEGGPCP 2906
Query: 1387 PRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCT 1446
C +C+ +C GC C G L+ SC+ C C G+ Y + C
Sbjct: 2907 RLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSC- 2965
Query: 1447 RRCRCFRRNVIQCDPRQCK-----------SDEECALRNGVRGCFSTKTSYCLAAGG 1492
C C + C +C S C+ G+R F T+ A GG
Sbjct: 2966 NNCTCV-SGKMACTSERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGG 3021
Score = 48.5 bits (114), Expect = 7e-05
Identities = 36/140 (25%), Positives = 51/140 (36%), Gaps = 7/140 (5%)
Query: 520 GSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDL------CSVRDNGTLLCQAIQAYAL 573
G + G + PL + DP A SC + L C V +G + +A AL
Sbjct: 4586 GRPWTGAPHLCTAPLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEAL 4645
Query: 574 VCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCAT-PCTEGCE 632
P G + C + CP +C+DL C PC GC
Sbjct: 4646 CGGGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCR 4705
Query: 633 CNQGFVLSTSQCVPLHKCGC 652
C G ++ +CVP+ C C
Sbjct: 4706 CPPGQLVQDGRCVPISSCRC 4725
Score = 47.4 bits (111), Expect = 2e-04
Identities = 29/103 (28%), Positives = 36/103 (34%), Gaps = 9/103 (8%)
Query: 594 TVQCPS---FSHYSVCTSS---CPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPL 647
T QCP F C CP C C C GC C G L + C+P
Sbjct: 2883 TAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPR 2942
Query: 648 HKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTC 690
+C C G Y G A + C C G + C ++ C
Sbjct: 2943 SQCPCQLHGQLYASGAM--ARLDSCNNCTC-VSGKMACTSERC 2982
Score = 46.2 bits (108), Expect = 3e-04
Identities = 35/107 (32%), Positives = 41/107 (38%), Gaps = 14/107 (13%)
Query: 596 QCPSFSHYSVCTSSCPDTCSDLTASRNCAT-PCTEGCECNQGFVLSTSQCVPLHKCGCDF 654
+CP S C +SCP C L C PC GC C G +L CVP C C
Sbjct: 4817 ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQ 4876
Query: 655 D----GHYYTMGEFFW-------ATANCTVQCLCEEGGDVYCFNKTC 690
G T+ E T NCT +C+C GG C C
Sbjct: 4877 HSLPWGLTLTLEEQAQELPPGTVLTRNCT-RCVC-HGGAFSCSLVDC 4921
Score = 44.7 bits (104), Expect = 0.001
Identities = 30/109 (27%), Positives = 39/109 (35%), Gaps = 11/109 (10%)
Query: 980 CPLECPENSHFEECIT-CTETCETLTLGPICVDS--CSEGCQCDEGYALLGSQCVTRSEC 1036
C CP C C C L G +C D C +GC+C +G CV C
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
Query: 1037 GC-NFEGHQLATNETFWVDLDCQIFC-YCSGTDNRVHCETIPCKDDEYC 1083
C + +GH A Q C CS ++ C PC +C
Sbjct: 4118 DCTDAQGHSWAPGSQH------QDACNNCSCQAGQLSCTAQPCPPPTHC 4160
Score = 43.5 bits (101), Expect = 0.002
Identities = 30/116 (25%), Positives = 41/116 (35%), Gaps = 13/116 (11%)
Query: 597 CPSFSHYSVCTSSCPDTCSDLTASRNCAT--PCTEGCECNQGFVLSTSQCVPLHKCGCDF 654
C + C S C C+ + + C PC GC C +G + C+P +C C
Sbjct: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNC-- 4480
Query: 655 DGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRE 710
H G +Q C+E C C GE+ G QG P E
Sbjct: 4481 -WHTSAAGAGMTLAPGDRLQLGCKE-----C---ECRRGELHCTSQGCQGLLPLSE 4527
Score = 43.1 bits (100), Expect = 0.003
Identities = 23/97 (23%), Positives = 32/97 (32%), Gaps = 3/97 (3%)
Query: 1372 CPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDG 1431
CP + + C CA + + C GCHC +G +L C+ C C +G
Sbjct: 3090 CPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEG 3148
Query: 1432 KYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDE 1468
Y P C C + C C E
Sbjct: 3149 HLYPPGSTVVRP--CENCSCVSGLIANCSSWPCAEGE 3183
Score = 42.7 bits (99), Expect = 0.004
Identities = 25/110 (22%), Positives = 40/110 (36%), Gaps = 4/110 (3%)
Query: 1364 NYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCS--HYCVEGCHCDAGYVLNGKSCIL 1421
N C CP +C + C RC+ ++ C C +GC C G + C+
Sbjct: 4054 NPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVP 4113
Query: 1422 PHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECA 1471
C C +D + + + D C C + + C + C CA
Sbjct: 4114 IGHCDC-TDAQGHSWAPGSQHQDACNNCSC-QAGQLSCTAQPCPPPTHCA 4161
Score = 42.4 bits (98), Expect = 0.005
Identities = 41/147 (27%), Positives = 54/147 (36%), Gaps = 18/147 (12%)
Query: 1339 QTACSWLQNYASTCQTQGITVTGWRNYTSC------TVTCPPNSHYESCVSVCQPRCAAI 1392
Q C QN TC + R C TC ++ C C C I
Sbjct: 1773 QRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAP-CPLTCDDI 1831
Query: 1393 RLKSDC--SHYCVE-GCHCDAGYVLNGKS-CILPHSCGCYSDGKYYEPKQLFWNSDCTRR 1448
+ C C GC C G VL + C+ P C C DG Y P Q +DC +
Sbjct: 1832 SGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRI-KADC-QL 1889
Query: 1449 CRCFRRNVIQCDPRQCKSDEECALRNG 1475
C C PR+C+ + +CA+ G
Sbjct: 1890 CICQDGR-----PRRCRLNPDCAVDCG 1911
Score = 42.4 bits (98), Expect = 0.005
Identities = 27/77 (35%), Positives = 30/77 (38%), Gaps = 3/77 (3%)
Query: 964 CKNADVEVGPWRTYDFCPLECPENSHFEECIT-CTETCETLTLGPICV-DSCSEGCQCDE 1021
C+ D E CP ECP C T C C L G ICV + C GC C
Sbjct: 4799 CQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPG 4857
Query: 1022 GYALLGSQCVTRSECGC 1038
G L CV + C C
Sbjct: 4858 GQLLHNGTCVPPTACPC 4874
Score = 41.6 bits (96), Expect = 0.008
Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 2/77 (2%)
Query: 1352 CQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDC-SHYCVEGCHCDA 1410
CQ Q N C CPP +C + C C ++ + C C GC C
Sbjct: 4799 CQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPG 4857
Query: 1411 GYVLNGKSCILPHSCGC 1427
G +L+ +C+ P +C C
Sbjct: 4858 GQLLHNGTCVPPTACPC 4874
Score = 40.8 bits (94), Expect = 0.014
Identities = 28/103 (27%), Positives = 36/103 (34%), Gaps = 10/103 (9%)
Query: 1366 TSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVL--NGKSCILPH 1423
T+CT + Y C C C + C C GC+C G VL NG C+ P
Sbjct: 3309 TNCTAI--EGAEYSPCGPPCPRSCDDL---VHCVWRCQPGCYCPPGQVLSSNGAICVQPG 3363
Query: 1424 SCGCYS--DGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQC 1464
C C G+ + P D C C + C C
Sbjct: 3364 HCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGR-LNCTDLPC 3405
Score = 40.4 bits (93), Expect = 0.019
Identities = 27/102 (26%), Positives = 37/102 (36%), Gaps = 10/102 (9%)
Query: 1371 TCPPNSHYESCVSVCQPRCAAIRLKSDCSHY--CVEGCHCDAGYVLNGKSCILPHSCGCY 1428
+C P + +C S C CA C C GC+C G + CI P C C+
Sbjct: 4422 SCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCW 4481
Query: 1429 -----SDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCK 1465
G P C + C C RR + C + C+
Sbjct: 4482 HTSAAGAGMTLAPGDRL-QLGC-KECEC-RRGELHCTSQGCQ 4520
Score = 38.9 bits (89), Expect = 0.055
Identities = 32/123 (26%), Positives = 48/123 (39%), Gaps = 16/123 (13%)
Query: 1367 SCT-VTC--PPNSHYESC----VSVCQPRCA---AIRLKSDCSHYCVEGCHCDAGYVLN- 1415
SC+ V C PP ++ + +C+ C A + +S+CS GC C G+ +
Sbjct: 4915 SCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQ 4974
Query: 1416 GKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVI---QCDPRQCKSDEECAL 1472
C+ C C+ G+ + P W C C C + C P C EE L
Sbjct: 4975 AGPCVPEDHCECWHLGRPHLPGS-EWQEAC-ESCLCLSGRPVCTQHCSPLTCAQGEEMVL 5032
Query: 1473 RNG 1475
G
Sbjct: 5033 EPG 5035
Score = 38.1 bits (87), Expect = 0.094
Identities = 52/200 (26%), Positives = 70/200 (35%), Gaps = 44/200 (22%)
Query: 1332 CIDGGAVQTACSW-LQNYASTCQT--QGITVTGWRNYTS-CTVTCPPNSHYESCVSVCQP 1387
C D GA +C W L S CQ G WR + C C ESC P
Sbjct: 4606 CPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCP 4665
Query: 1388 RCAA------IRLKSDCSHYCVE--------------GCHCDAGYVLNGKSCILPHSCGC 1427
C A + + C H C + GC C G ++ C+ SC C
Sbjct: 4666 ECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRC 4725
Query: 1428 --YSDGKYYE--PKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTK 1483
S +E P Q DC + C C +++ C ++C V G +S
Sbjct: 4726 GLPSANASWELAPAQAV-QLDC-QNCTCVNESLV-CPHQECP----------VLGPWSAW 4772
Query: 1484 TSYCLAAGGGVF---RTFDG 1500
+S GGG RT +G
Sbjct: 4773 SSCSAPCGGGTMERHRTCEG 4792
Score = 37.0 bits (84), Expect = 0.21
Identities = 33/125 (26%), Positives = 48/125 (38%), Gaps = 31/125 (24%)
Query: 972 GPWRTYDFCP-LECP-------ENSHFEEC-ITCTETCETLTLGPICVDSCSEGCQCDEG 1022
GP + C L CP E + + C C +C+ L CV C GC C G
Sbjct: 3293 GPRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVH---CVWRCQPGCYCPPG 3349
Query: 1023 YALL--GSQCVTRSECGC--------NFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHC 1072
L G+ CV C C + G +LA + C +C+ + R++C
Sbjct: 3350 QVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPD------GCN---HCTCLEGRLNC 3400
Query: 1073 ETIPC 1077
+PC
Sbjct: 3401 TDLPC 3405
Score = 36.2 bits (82), Expect = 0.36
Identities = 15/43 (34%), Positives = 20/43 (46%)
Query: 996 CTETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGC 1038
C +C C C EGC+C G L ++C+ SEC C
Sbjct: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPC 2677
Score = 35.4 bits (80), Expect = 0.61
Identities = 18/70 (25%), Positives = 23/70 (32%), Gaps = 3/70 (4%)
Query: 588 QTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNC---ATPCTEGCECNQGFVLSTSQC 644
Q C C CP +C DL+ C + C C C G + C
Sbjct: 3520 QENSTQCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLC 3579
Query: 645 VPLHKCGCDF 654
VP C C +
Sbjct: 3580 VPPAHCRCQY 3589
Score = 35.4 bits (80), Expect = 0.61
Identities = 22/84 (26%), Positives = 28/84 (33%), Gaps = 3/84 (3%)
Query: 958 ARYASACKNADVEVGPWRTYDFCPLECPENSHFEECIT-CTETCETLTLGPICVD--SCS 1014
AR + C D P + C F C + C C T +C D C
Sbjct: 4397 ARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQ 4456
Query: 1015 EGCQCDEGYALLGSQCVTRSECGC 1038
GC C +G C+ EC C
Sbjct: 4457 PGCYCPKGLLEQAGGCIPPEECNC 4480
Score = 35.0 bits (79), Expect = 0.80
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 597 CPSFSHYSVCT--SSCPDTCSDLTASRNCATP-CTEGCECNQGFVLSTSQCVPLHKCGC 652
CP+ Y C CP +C+ +T C + C EGC C +G CV +C C
Sbjct: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACV--QECPC 3753
Score = 34.7 bits (78), Expect = 1.0
Identities = 25/89 (28%), Positives = 31/89 (34%), Gaps = 15/89 (16%)
Query: 1342 CSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCV--SVCQPRCAAIRLKSDC- 1398
C + TC TQ G CP Y C C CA + + C
Sbjct: 3677 CPGPARQSRTCSTQVCREAG----------CPAGRLYRECQPGEGCPFSCAHVTQQVGCF 3726
Query: 1399 SHYCVEGCHCDAGYVLNGKSCILPHSCGC 1427
S C EGCHC G + +C+ C C
Sbjct: 3727 SEGCEEGCHCPEGTFQHRLACV--QECPC 3753
Score = 34.7 bits (78), Expect = 1.0
Identities = 34/129 (26%), Positives = 45/129 (34%), Gaps = 20/129 (15%)
Query: 946 SGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECIT------CTET 999
SGG ++ A C+ PW CPE + T C +
Sbjct: 4632 SGGFRLRWREAEALCGGGCRE------PWAQESCNGGPCPECEAQDTVFTLDCANQCPHS 4685
Query: 1000 CETLTLGPICVDS-CSEGCQCDEGYALLGSQCVTRSECGCNF----EGHQLATNETFWVD 1054
C L C+ C GC+C G + +CV S C C +LA + V
Sbjct: 4686 CADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQA--VQ 4743
Query: 1055 LDCQIFCYC 1063
LDCQ C C
Sbjct: 4744 LDCQ-NCTC 4751
Score = 32.0 bits (71), Expect = 6.7
Identities = 20/59 (33%), Positives = 24/59 (40%), Gaps = 6/59 (10%)
Query: 984 CPENSHFEECIT---CTETCETLTLGPICV-DSCSEGCQCDEGYALLGSQCVTRSECGC 1038
CP + EC C +C +T C + C EGC C EG CV EC C
Sbjct: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACV--QECPC 3753
>gi|119220571 zymogen granule membrane glycoprotein 2 isoform 2 [Homo
sapiens]
Length = 534
Score = 206 bits (524), Expect = 2e-52
Identities = 120/343 (34%), Positives = 180/343 (52%), Gaps = 19/343 (5%)
Query: 1749 TEWIEKENCS--GVVEDPCVGADCPNRTCELGNGRELCGCIEPPPYGNNSHDI--IDAEV 1804
T W C+ VED C A P C N C C + NS D+ + ++
Sbjct: 169 TPWCNLRYCTDPSTVEDKCEKACRPEEECLALNSTWGCFCRQDL----NSSDVHSLQPQL 224
Query: 1805 TCKAAQMEVSISKCKLFQLGFEREGVR-INDRQCTGI---EGEDFISFQINNTKGNCGNI 1860
C +++V + KC L LG E + + D C+ I E +++S C NI
Sbjct: 225 DCGPREIKVKVDKCLLGGLGLGEEVIAYLRDPNCSSILQTEERNWVSVTSPVQASACRNI 284
Query: 1861 VQSNGTHIMYKNTLWIESANNTGNIITRDRTINVEFSCAYELDIKISLDSVVKPMLSVIN 1920
++ N TH +YKNTL + + I RD +N+ F CAY LD+K+SL + ++P++S +N
Sbjct: 285 LERNQTHAIYKNTLSL-----VNDFIIRDTILNINFQCAYPLDMKVSLQAALQPIVSSLN 339
Query: 1921 LTVPTQEGSFITKMALYKNASYKHPYRQGEVVLTTRDVLYVGVFVVGADATHLILTLNKC 1980
++V G FI +MAL+++ +Y +PY V L+ VLYVG + D + L L C
Sbjct: 340 VSVDGN-GEFIVRMALFQDQNYTNPYEGDAVELSVESVLYVGAILEQGDTSRFNLVLRNC 398
Query: 1981 YATPTRDSNDKLRYFIIEGGCQNLKDNTIGIEENAVSLTCRFHVTVFKFIGDYDEVHLHC 2040
YATPT D D ++YFII C N +D+TI +EEN S RF V +F F G YD V LHC
Sbjct: 399 YATPTEDKADLVKYFIIRNSCSNQRDSTIHVEENGQSSESRFSVQMFMFAGHYDLVFLHC 458
Query: 2041 AVSLCDSEKYSCKITCPHNSRIATDYTKEPKEQIISVGPIRRK 2083
+ LCDS C+ +C S++ ++ +++ +GPI R+
Sbjct: 459 EIHLCDSLNEQCQPSC-SRSQVRSEVPAIDLARVLDLGPITRR 500
>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
sapiens]
Length = 2134
Score = 206 bits (523), Expect = 3e-52
Identities = 254/1087 (23%), Positives = 394/1087 (36%), Gaps = 176/1087 (16%)
Query: 520 GSDYCGFLNKTDGPLWE-CGTVVD-PTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQA 577
G +C NK G +E CG V + C+ + C RD T C + +C +
Sbjct: 685 GIQHC---NKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDK-TSTCDTYSELSRLCAS 740
Query: 578 LGI-PIGDWRTQTGCV-STVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQ 635
G WR+ + V T +CP Y C S P TCS++ ++ + C GC C +
Sbjct: 741 DGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPFQD--SECVSGCTCPE 798
Query: 636 GFVLST----SQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCG 691
G++L +CV +C C+ G Y GE C QC C++ C C
Sbjct: 799 GYLLDDIGEKGKCVLKAECPCESSGTVYQPGEV--REGPCGSQCTCQDA-KWSCTEALCP 855
Query: 692 SGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLE 751
C VE L TFDG Y FP + + E
Sbjct: 856 GR--CKVE------------------GSSLTTFDGVKYNFPGNCHFLAVHN-----EDWS 890
Query: 752 IDINKKKPDAGPAW--LRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIY 809
I + + +G L + +L+ + S+ + ++ ++ S K++I+
Sbjct: 891 ISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIF 950
Query: 810 RNKNS-TTVESKGVVTVQYSDIGL--LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGK 866
+S VE+ V +Q + + LY+ + F T GLCG YN A D+F
Sbjct: 951 NASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNI 1010
Query: 867 CTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLEC 926
F SW E+ + G+ + + E KF + CGI+ D S+ C
Sbjct: 1011 LEKTSQAFANSW----EMMSCPKGNPSSCISIEKE--KF--AERHCGILLD-SSGPLASC 1061
Query: 927 HGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPE 986
H +VN Y+ C C ++ LC + Y AC + + WRT C CP
Sbjct: 1062 HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPS 1120
Query: 987 NSHFEECI-TCTETCETLTLGPICVDSCS---EGCQC-DEGYALLGSQCVTRSECGCNFE 1041
F+ + C +C +L+ D +GC C D Y CV +S+C C
Sbjct: 1121 GLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYIN 1180
Query: 1042 GHQLATNETFWVD----------LDCQI-----FCYCSGTDNRVHC-------------- 1072
+ + +D L CQI CSG V C
Sbjct: 1181 DEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCS 1240
Query: 1073 --------ETIPCKDDEYCME--------------------------EG----------- 1087
E +PCK +C E EG
Sbjct: 1241 TRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECT 1300
Query: 1088 ---GLYYC-QARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVV 1143
G + C Q C + G GH TFDG + F C + +F ++
Sbjct: 1301 CIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFR--IL 1358
Query: 1144 TAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSF 1203
T + L +++ V +IV+ K T + ++E +L +I +
Sbjct: 1359 TESVPCCEDGLTC-SRKIIVAFQDQNIVLQDG-KVTAVKSTES--KKCELNANAYSIHTV 1414
Query: 1204 GFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSV 1263
G +++++ G+ V++D T LS+ + + GLCG NG+ DD +AS
Sbjct: 1415 GLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGA 1474
Query: 1264 NEFGQSWVK----RDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVN 1319
EFG SW DT Q D P C K K + L +++ F CH+KV+
Sbjct: 1475 LEFGNSWKTSQECSDTVAQTFPCDSNPYC-KAWAVRKCEIL------RDSTFRDCHNKVD 1527
Query: 1320 PTFFYKNCLFDSCIDG--GAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNS- 1376
P+ ++ C+ ++C G C+ + YA C G+ V+ WR C V C +
Sbjct: 1528 PSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNA 1586
Query: 1377 ------HYESCVSVCQPRCAAIRLKSDCSHYCVEGCHC----DAGYV-LNGKSCILPHSC 1425
HYE C +V C +L +EGC+ A Y+ N C+ C
Sbjct: 1587 PGECRWHYEPCGTVTAKTCKD-QLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSEC 1645
Query: 1426 GCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTS 1485
C+ + P +C R C C ++C + ST +
Sbjct: 1646 SCFYNDVI--PAGGVIEDNCGRTCYCI-AGQLECSETAPTNSTFAVSTTTATTILSTGAA 1702
Query: 1486 YCLAAGG 1492
L GG
Sbjct: 1703 ITLVTGG 1709
Score = 110 bits (276), Expect = 1e-23
Identities = 109/430 (25%), Positives = 169/430 (39%), Gaps = 50/430 (11%)
Query: 272 VFWDDLNCTVKCRCLDFNN--EIYCQEASCSPYEVCEPKGKFFYCSAVETST-CVVFGEP 328
VF +D C+ R D + + C E +C KG + C+ E T C ++GE
Sbjct: 1272 VFPNDCPCSFGGREYDEGSVTSVGCNECTCI-------KGSWS-CTQNECQTICHIYGEG 1323
Query: 329 HYHTFDGFLFHFQGSCAY-LLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNG 387
H TFDG + F G C Y L C + F + ++ ++ +++ V
Sbjct: 1324 HVRTFDGKSYSFDGLCQYSFLEDYCGHENGT--FRILTESVPCCEDGLTCSRKIIVAFQD 1381
Query: 388 YKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASI 447
I++ G VK + S L+ I+ G+ ++ G++V +D S+
Sbjct: 1382 QNIVLQDGKVTAVKSTE---SKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSV 1438
Query: 448 SVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNC 507
+ ++ CGLCGN N + DDF A L+ G S WK C D
Sbjct: 1439 ILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNS-------WKTSQECSDTV 1491
Query: 508 TQ---CDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLL 564
Q CD+ + C L D +C VDP+A+ C+ + C+ G L
Sbjct: 1492 AQTFPCDSNPYCKAWAVRKCEILR--DSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYL 1549
Query: 565 --CQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFS-------HYSVCTSSCPDTCS 615
C A+ YA C A+G+ + WR C V C ++ HY C + TC
Sbjct: 1550 GFCTAVAMYAEACSAVGVCV-SWRKPNLC--PVYCDYYNAPGECRWHYEPCGTVTAKTCK 1606
Query: 616 DLTASRNCATPCTEGC--ECNQGFVL---STSQCVPLHKCGCDFDGHYYTMGEFFWATAN 670
D + ++ EGC +C +T +CV L +C C ++ G N
Sbjct: 1607 DQLVGQKFSS-LLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVIPAGGVI---EDN 1662
Query: 671 CTVQCLCEEG 680
C C C G
Sbjct: 1663 CGRTCYCIAG 1672
Score = 103 bits (258), Expect = 1e-21
Identities = 84/361 (23%), Positives = 138/361 (38%), Gaps = 41/361 (11%)
Query: 1402 CVEGCHCDAGYVLNGKS-CILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCD 1460
C GC C G V N K C+ P+ C C G+ Y+ + S C C + + C
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV--TSVGCNECTCIKGSW-SCT 1309
Query: 1461 PRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAF-VLSTICQK 1519
+C++ C G G RTFDG F C + L C
Sbjct: 1310 QNECQT-------------------ICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGH 1350
Query: 1520 LPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLAT 1579
+ +F+++ LT + ++ I++ D V T+ + A
Sbjct: 1351 -ENGTFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAY 1409
Query: 1580 KIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGK 1639
I++ +L++ I + ++ + + + KVCGLCGN NGDL DD+ T
Sbjct: 1410 SIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSS 1469
Query: 1640 PVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKG 1699
++ SWKT + C++ + CD+ K C L D
Sbjct: 1470 VASGALEFGNSWKT--------SQECSDTVAQTFP--CDSNPYCKAWAVRKCEILRD--S 1517
Query: 1700 FFQPCYGLLDPLPFYESCYLDGC---YSHKKFQLCGSLAAYGEACRSFGILSTEWIEKEN 1756
F+ C+ +DP +++ C + C K C ++A Y EAC + G+ W +
Sbjct: 1518 TFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGV-CVSWRKPNL 1576
Query: 1757 C 1757
C
Sbjct: 1577 C 1577
Score = 89.7 bits (221), Expect = 3e-17
Identities = 122/576 (21%), Positives = 211/576 (36%), Gaps = 84/576 (14%)
Query: 1311 FSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGI-TVTGWRNYTSC- 1368
F KC + YK D + C + C + G T WR+ +
Sbjct: 697 FEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVV 756
Query: 1369 --TVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLN-----GKSCIL 1421
T CP Y+ C C+ + D CV GC C GY+L+ GK C+L
Sbjct: 757 CETQRCPEQHIYKECGPSNPATCSNVAPFQDSE--CVSGCTCPEGYLLDDIGEKGK-CVL 813
Query: 1422 PHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFS 1481
C C S G Y+P ++ C +C C D + ++ C R V G
Sbjct: 814 KAECPCESSGTVYQPGEVR-EGPCGSQCTCQ-------DAKWSCTEALCPGRCKVEGSSL 865
Query: 1482 TKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTI 1541
T TFDG FP NC F+ + + IS +L S T
Sbjct: 866 T--------------TFDGVKYNFPGNCHFL--AVHNEDWSISVELR---PCPSGQTGTC 906
Query: 1542 ISPVYFYINE----EQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQ 1597
++ V +N ++ + N TV + + + + +S +L ++T ++
Sbjct: 907 LNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVK 966
Query: 1598 IYYNGFNVIKISIS--ERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNG 1655
+ V+++ +S GLCG++N DD+++ + +S A SW+
Sbjct: 967 LQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS 1026
Query: 1656 MQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYE 1715
K SC ++ ++A + +C L D G C+ +++P P++E
Sbjct: 1027 CPKGN-PSSCISIEKEKFA-------------ERHCGILLDSSGPLASCHPIVNPKPYHE 1072
Query: 1716 SCYLDGC-YSHKKFQLCGSLAAYGEACRSFGILSTEW---IEKENC-SGVV--------E 1762
C C + + LC L Y +AC W + + +C SG+V
Sbjct: 1073 ECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACN 1132
Query: 1763 DPCVGADCPNRTCELGN-GRELCGCIEPPPYGNNSHDIIDAEVTCKAAQMEVSISKCKLF 1821
C +R+C++ + + C C + N + ++ ++ C + K
Sbjct: 1133 SSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKL--- 1189
Query: 1822 QLGFEREGVRINDRQCTGIEGEDFISFQINNTKGNC 1857
+ I+D +C +G I+ T NC
Sbjct: 1190 --------IHIDDNKCVCRDGILLCQIPIDLTLQNC 1217
Score = 88.2 bits (217), Expect = 8e-17
Identities = 102/439 (23%), Positives = 165/439 (37%), Gaps = 44/439 (10%)
Query: 258 NGCTSRGQFLRRGEVFWDDLN----CTVKCRC-LDFNNEIY----CQEASCSPYEVCEPK 308
+GCT +L DD+ C +K C + + +Y +E C C+
Sbjct: 792 SGCTCPEGYLL------DDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQD- 844
Query: 309 GKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNE 368
K+ A+ C V G TFDG ++F G+C +L + S+ +
Sbjct: 845 AKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVHNEDWSISVELRPCPSGQT 903
Query: 369 HRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGIS-T 427
++V+ + SV V+ Y S G V ND + + ++I+ + S
Sbjct: 904 GTCLNSVTLLLNSSVPVDKYVF----NSDGTV-TNDKIRNQGYYYS-DKIQIFNASSSYL 957
Query: 428 AVETDFG--LLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLD 485
VET F L + +S+P + T GLCG+YN DDF+ +
Sbjct: 958 QVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQA 1017
Query: 486 LGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTA 545
SW + C G +C + E F +CG L + GPL C +V+P
Sbjct: 1018 FANSWEMM----SCPKGNPSSCI----SIEKEKFAERHCGILLDSSGPLASCHPIVNPKP 1069
Query: 546 FVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSV 605
+ C C+ ++ LC + Y C I WRT + CPS +
Sbjct: 1070 YHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTG---LCEHSCPSGLVFKY 1126
Query: 606 CTSSCPDTCSDLT-ASRNCATP--CTEGCECNQG-FVLSTSQCVPLHKCGCDFDGHYYTM 661
+C +C L+ R+C +GC C + + CV +C C +
Sbjct: 1127 NVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQP 1186
Query: 662 GEFFWATANCTVQCLCEEG 680
G+ N +C+C +G
Sbjct: 1187 GKLIHIDDN---KCVCRDG 1202
Score = 33.9 bits (76), Expect = 1.8
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
Query: 330 YHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRR 371
Y +F+G +F F+ SC Y R C+++ F++E K + R
Sbjct: 616 YKSFNGRIFFFESSCPYTFCRHCIESGG--DFNIEIKRNNDR 655
>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
sapiens]
Length = 2134
Score = 206 bits (523), Expect = 3e-52
Identities = 254/1087 (23%), Positives = 394/1087 (36%), Gaps = 176/1087 (16%)
Query: 520 GSDYCGFLNKTDGPLWE-CGTVVD-PTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQA 577
G +C NK G +E CG V + C+ + C RD T C + +C +
Sbjct: 685 GIQHC---NKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDK-TSTCDTYSELSRLCAS 740
Query: 578 LGI-PIGDWRTQTGCV-STVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQ 635
G WR+ + V T +CP Y C S P TCS++ ++ + C GC C +
Sbjct: 741 DGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQD--SECVSGCTCPE 798
Query: 636 GFVLST----SQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCG 691
G++L +CV +C C+ G Y GE C QC C++ C C
Sbjct: 799 GYLLDDIGEKGKCVLKAECPCESSGTVYQPGEV--REGPCGSQCTCQDA-KWSCTEALCP 855
Query: 692 SGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLE 751
C VE L TFDG Y FP + + E
Sbjct: 856 GR--CKVE------------------GSSLTTFDGVKYNFPGNCHFLAVHN-----EDWS 890
Query: 752 IDINKKKPDAGPAW--LRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIY 809
I + + +G L + +L+ + S+ + ++ ++ S K++I+
Sbjct: 891 ISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIF 950
Query: 810 RNKNS-TTVESKGVVTVQYSDIGL--LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGK 866
+S VE+ V +Q + + LY+ + F T GLCG YN A D+F
Sbjct: 951 NASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNI 1010
Query: 867 CTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLEC 926
F SW E+ + G+ + + E KF + CGI+ D S+ C
Sbjct: 1011 LEKTSQAFANSW----EMMSCPKGNPSSCISIEKE--KF--AERHCGILLD-SSGPLASC 1061
Query: 927 HGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPE 986
H +VN Y+ C C ++ LC + Y AC + + WRT C CP
Sbjct: 1062 HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPS 1120
Query: 987 NSHFEECI-TCTETCETLTLGPICVDSCS---EGCQC-DEGYALLGSQCVTRSECGCNFE 1041
F+ + C +C +L+ D +GC C D Y CV +S+C C
Sbjct: 1121 GLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYIN 1180
Query: 1042 GHQLATNETFWVD----------LDCQI-----FCYCSGTDNRVHC-------------- 1072
+ + +D L CQI CSG V C
Sbjct: 1181 DEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCS 1240
Query: 1073 --------ETIPCKDDEYCME--------------------------EG----------- 1087
E +PCK +C E EG
Sbjct: 1241 TRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECT 1300
Query: 1088 ---GLYYC-QARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVV 1143
G + C Q C + G GH TFDG + F C + +F ++
Sbjct: 1301 CIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFR--IL 1358
Query: 1144 TAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSF 1203
T + L +++ V +IV+ K T + ++E +L +I +
Sbjct: 1359 TESVPCCEDGLTC-SRKIIVAFQDQNIVLQDG-KVTAVKSTES--KKCELNANAYSIHTV 1414
Query: 1204 GFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSV 1263
G +++++ G+ V++D T LS+ + + GLCG NG+ DD +AS
Sbjct: 1415 GLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGA 1474
Query: 1264 NEFGQSWVK----RDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVN 1319
EFG SW DT Q D P C K K + L +++ F CH+KV+
Sbjct: 1475 LEFGNSWKTSQECSDTVAQTFPCDSNPYC-KAWAVRKCEIL------RDSTFRDCHNKVD 1527
Query: 1320 PTFFYKNCLFDSCIDG--GAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNS- 1376
P+ ++ C+ ++C G C+ + YA C G+ V+ WR C V C +
Sbjct: 1528 PSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNA 1586
Query: 1377 ------HYESCVSVCQPRCAAIRLKSDCSHYCVEGCHC----DAGYV-LNGKSCILPHSC 1425
HYE C +V C +L +EGC+ A Y+ N C+ C
Sbjct: 1587 PGECRWHYEPCGTVTAKTCKD-QLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSEC 1645
Query: 1426 GCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTS 1485
C+ + P +C R C C ++C + ST +
Sbjct: 1646 SCFYNDVI--PAGGVIEDNCGRTCYCI-AGQLECSETAPTNSTFAVSTTTATTILSTGAA 1702
Query: 1486 YCLAAGG 1492
L GG
Sbjct: 1703 ITLVTGG 1709
Score = 110 bits (276), Expect = 1e-23
Identities = 109/430 (25%), Positives = 169/430 (39%), Gaps = 50/430 (11%)
Query: 272 VFWDDLNCTVKCRCLDFNN--EIYCQEASCSPYEVCEPKGKFFYCSAVETST-CVVFGEP 328
VF +D C+ R D + + C E +C KG + C+ E T C ++GE
Sbjct: 1272 VFPNDCPCSFGGREYDEGSVTSVGCNECTCI-------KGSWS-CTQNECQTICHIYGEG 1323
Query: 329 HYHTFDGFLFHFQGSCAY-LLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNG 387
H TFDG + F G C Y L C + F + ++ ++ +++ V
Sbjct: 1324 HVRTFDGKSYSFDGLCQYSFLEDYCGHENGT--FRILTESVPCCEDGLTCSRKIIVAFQD 1381
Query: 388 YKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASI 447
I++ G VK + S L+ I+ G+ ++ G++V +D S+
Sbjct: 1382 QNIVLQDGKVTAVKSTE---SKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSV 1438
Query: 448 SVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNC 507
+ ++ CGLCGN N + DDF A L+ G S WK C D
Sbjct: 1439 ILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNS-------WKTSQECSDTV 1491
Query: 508 TQ---CDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLL 564
Q CD+ + C L D +C VDP+A+ C+ + C+ G L
Sbjct: 1492 AQTFPCDSNPYCKAWAVRKCEILR--DSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYL 1549
Query: 565 --CQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFS-------HYSVCTSSCPDTCS 615
C A+ YA C A+G+ + WR C V C ++ HY C + TC
Sbjct: 1550 GFCTAVAMYAEACSAVGVCV-SWRKPNLC--PVYCDYYNAPGECRWHYEPCGTVTAKTCK 1606
Query: 616 DLTASRNCATPCTEGC--ECNQGFVL---STSQCVPLHKCGCDFDGHYYTMGEFFWATAN 670
D + ++ EGC +C +T +CV L +C C ++ G N
Sbjct: 1607 DQLVGQKFSS-LLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVIPAGGVI---EDN 1662
Query: 671 CTVQCLCEEG 680
C C C G
Sbjct: 1663 CGRTCYCIAG 1672
Score = 103 bits (258), Expect = 1e-21
Identities = 84/361 (23%), Positives = 138/361 (38%), Gaps = 41/361 (11%)
Query: 1402 CVEGCHCDAGYVLNGKS-CILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCD 1460
C GC C G V N K C+ P+ C C G+ Y+ + S C C + + C
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV--TSVGCNECTCIKGSW-SCT 1309
Query: 1461 PRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAF-VLSTICQK 1519
+C++ C G G RTFDG F C + L C
Sbjct: 1310 QNECQT-------------------ICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGH 1350
Query: 1520 LPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLAT 1579
+ +F+++ LT + ++ I++ D V T+ + A
Sbjct: 1351 -ENGTFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAY 1409
Query: 1580 KIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGK 1639
I++ +L++ I + ++ + + + KVCGLCGN NGDL DD+ T
Sbjct: 1410 SIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSS 1469
Query: 1640 PVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKG 1699
++ SWKT + C++ + CD+ K C L D
Sbjct: 1470 VASGALEFGNSWKT--------SQECSDTVAQTFP--CDSNPYCKAWAVRKCEILRD--S 1517
Query: 1700 FFQPCYGLLDPLPFYESCYLDGC---YSHKKFQLCGSLAAYGEACRSFGILSTEWIEKEN 1756
F+ C+ +DP +++ C + C K C ++A Y EAC + G+ W +
Sbjct: 1518 TFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGV-CVSWRKPNL 1576
Query: 1757 C 1757
C
Sbjct: 1577 C 1577
Score = 89.7 bits (221), Expect = 3e-17
Identities = 122/576 (21%), Positives = 211/576 (36%), Gaps = 84/576 (14%)
Query: 1311 FSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGI-TVTGWRNYTSC- 1368
F KC + YK D + C + C + G T WR+ +
Sbjct: 697 FEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVV 756
Query: 1369 --TVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLN-----GKSCIL 1421
T CP Y+ C C+ + D CV GC C GY+L+ GK C+L
Sbjct: 757 CGTQRCPEQHIYKECGPSNPATCSNVAPFQDSE--CVSGCTCPEGYLLDDIGEKGK-CVL 813
Query: 1422 PHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFS 1481
C C S G Y+P ++ C +C C D + ++ C R V G
Sbjct: 814 KAECPCESSGTVYQPGEVR-EGPCGSQCTCQ-------DAKWSCTEALCPGRCKVEGSSL 865
Query: 1482 TKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTI 1541
T TFDG FP NC F+ + + IS +L S T
Sbjct: 866 T--------------TFDGVKYNFPGNCHFL--AVHNEDWSISVELR---PCPSGQTGTC 906
Query: 1542 ISPVYFYINE----EQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQ 1597
++ V +N ++ + N TV + + + + +S +L ++T ++
Sbjct: 907 LNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVK 966
Query: 1598 IYYNGFNVIKISIS--ERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNG 1655
+ V+++ +S GLCG++N DD+++ + +S A SW+
Sbjct: 967 LQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS 1026
Query: 1656 MQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYE 1715
K SC ++ ++A + +C L D G C+ +++P P++E
Sbjct: 1027 CPKGN-PSSCISIEKEKFA-------------ERHCGILLDSSGPLASCHPIVNPKPYHE 1072
Query: 1716 SCYLDGC-YSHKKFQLCGSLAAYGEACRSFGILSTEW---IEKENC-SGVV--------E 1762
C C + + LC L Y +AC W + + +C SG+V
Sbjct: 1073 ECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACN 1132
Query: 1763 DPCVGADCPNRTCELGN-GRELCGCIEPPPYGNNSHDIIDAEVTCKAAQMEVSISKCKLF 1821
C +R+C++ + + C C + N + ++ ++ C + K
Sbjct: 1133 SSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKL--- 1189
Query: 1822 QLGFEREGVRINDRQCTGIEGEDFISFQINNTKGNC 1857
+ I+D +C +G I+ T NC
Sbjct: 1190 --------IHIDDNKCVCRDGILLCQIPIDLTLQNC 1217
Score = 88.2 bits (217), Expect = 8e-17
Identities = 102/439 (23%), Positives = 165/439 (37%), Gaps = 44/439 (10%)
Query: 258 NGCTSRGQFLRRGEVFWDDLN----CTVKCRC-LDFNNEIY----CQEASCSPYEVCEPK 308
+GCT +L DD+ C +K C + + +Y +E C C+
Sbjct: 792 SGCTCPEGYLL------DDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQD- 844
Query: 309 GKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNE 368
K+ A+ C V G TFDG ++F G+C +L + S+ +
Sbjct: 845 AKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVHNEDWSISVELRPCPSGQT 903
Query: 369 HRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGIS-T 427
++V+ + SV V+ Y S G V ND + + ++I+ + S
Sbjct: 904 GTCLNSVTLLLNSSVPVDKYVF----NSDGTV-TNDKIRNQGYYYS-DKIQIFNASSSYL 957
Query: 428 AVETDFG--LLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLD 485
VET F L + +S+P + T GLCG+YN DDF+ +
Sbjct: 958 QVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQA 1017
Query: 486 LGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTA 545
SW + C G +C + E F +CG L + GPL C +V+P
Sbjct: 1018 FANSWEMM----SCPKGNPSSCI----SIEKEKFAERHCGILLDSSGPLASCHPIVNPKP 1069
Query: 546 FVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSV 605
+ C C+ ++ LC + Y C I WRT + CPS +
Sbjct: 1070 YHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTG---LCEHSCPSGLVFKY 1126
Query: 606 CTSSCPDTCSDLT-ASRNCATP--CTEGCECNQG-FVLSTSQCVPLHKCGCDFDGHYYTM 661
+C +C L+ R+C +GC C + + CV +C C +
Sbjct: 1127 NVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQP 1186
Query: 662 GEFFWATANCTVQCLCEEG 680
G+ N +C+C +G
Sbjct: 1187 GKLIHIDDN---KCVCRDG 1202
Score = 33.9 bits (76), Expect = 1.8
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
Query: 330 YHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRR 371
Y +F+G +F F+ SC Y R C+++ F++E K + R
Sbjct: 616 YKSFNGRIFFFESSCPYTFCRHCIESGG--DFNIEIKRNNDR 655
>gi|119220569 zymogen granule membrane glycoprotein 2 isoform 1 [Homo
sapiens]
Length = 537
Score = 205 bits (521), Expect = 4e-52
Identities = 120/346 (34%), Positives = 180/346 (52%), Gaps = 22/346 (6%)
Query: 1749 TEWIEKENCS-----GVVEDPCVGADCPNRTCELGNGRELCGCIEPPPYGNNSHDI--ID 1801
T W C+ VED C A P C N C C + NS D+ +
Sbjct: 169 TPWCNLRYCTVPRDPSTVEDKCEKACRPEEECLALNSTWGCFCRQDL----NSSDVHSLQ 224
Query: 1802 AEVTCKAAQMEVSISKCKLFQLGFEREGVR-INDRQCTGI---EGEDFISFQINNTKGNC 1857
++ C +++V + KC L LG E + + D C+ I E +++S C
Sbjct: 225 PQLDCGPREIKVKVDKCLLGGLGLGEEVIAYLRDPNCSSILQTEERNWVSVTSPVQASAC 284
Query: 1858 GNIVQSNGTHIMYKNTLWIESANNTGNIITRDRTINVEFSCAYELDIKISLDSVVKPMLS 1917
NI++ N TH +YKNTL + + I RD +N+ F CAY LD+K+SL + ++P++S
Sbjct: 285 RNILERNQTHAIYKNTLSL-----VNDFIIRDTILNINFQCAYPLDMKVSLQAALQPIVS 339
Query: 1918 VINLTVPTQEGSFITKMALYKNASYKHPYRQGEVVLTTRDVLYVGVFVVGADATHLILTL 1977
+N++V G FI +MAL+++ +Y +PY V L+ VLYVG + D + L L
Sbjct: 340 SLNVSVDGN-GEFIVRMALFQDQNYTNPYEGDAVELSVESVLYVGAILEQGDTSRFNLVL 398
Query: 1978 NKCYATPTRDSNDKLRYFIIEGGCQNLKDNTIGIEENAVSLTCRFHVTVFKFIGDYDEVH 2037
CYATPT D D ++YFII C N +D+TI +EEN S RF V +F F G YD V
Sbjct: 399 RNCYATPTEDKADLVKYFIIRNSCSNQRDSTIHVEENGQSSESRFSVQMFMFAGHYDLVF 458
Query: 2038 LHCAVSLCDSEKYSCKITCPHNSRIATDYTKEPKEQIISVGPIRRK 2083
LHC + LCDS C+ +C S++ ++ +++ +GPI R+
Sbjct: 459 LHCEIHLCDSLNEQCQPSC-SRSQVRSEVPAIDLARVLDLGPITRR 503
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.449
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,863,705
Number of Sequences: 37866
Number of extensions: 4448617
Number of successful extensions: 12009
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 155
Number of HSP's that attempted gapping in prelim test: 8419
Number of HSP's gapped (non-prelim): 1958
length of query: 2155
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2037
effective length of database: 13,779,330
effective search space: 28068495210
effective search space used: 28068495210
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.