Search of human proteins with 55769554

Search of human proteins with 55769554

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|55769554 protein tyrosine phosphatase, receptor type, f
polypeptide (PTPRF), interacting protein (liprin), alpha 4 [Homo
sapiens]
         (701 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|55769554 protein tyrosine phosphatase, receptor type, f polyp...  1402   0.0  
gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens]          892   0.0  
gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap...   793   0.0  
gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa...   793   0.0  
gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]          731   0.0  
gi|157837985 kazrin isoform E [Homo sapiens]                          179   1e-44
gi|29294627 PTPRF interacting protein binding protein 1 isoform ...   146   7e-35
gi|170784854 PTPRF interacting protein, binding protein 2 (lipri...   137   3e-32
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    42   0.001
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ...    40   0.006
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        40   0.010
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        40   0.010
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         40   0.010
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         40   0.010
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         40   0.010
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         40   0.010
gi|41322912 plectin 1 isoform 2 [Homo sapiens]                         40   0.010
gi|47607492 plectin 1 isoform 1 [Homo sapiens]                         40   0.010
gi|209862789 microtubule associated monoxygenase, calponin and L...    39   0.016
gi|29825823 hypothetical protein LOC283987 [Homo sapiens]              38   0.028
gi|32490572 erythrocyte membrane protein band 4.1-like 3 [Homo s...    37   0.048
gi|115511012 coiled-coil domain containing 136 [Homo sapiens]          37   0.062
gi|33147080 STAM binding protein-like 1 [Homo sapiens]                 37   0.081
gi|50962882 G patch domain containing 8 [Homo sapiens]                 37   0.081
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          36   0.14 
gi|223890252 glutamate receptor interacting protein 1 [Homo sapi...    35   0.18 
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]      35   0.18 
gi|45439327 periplakin [Homo sapiens]                                  35   0.18 
gi|8659574 transcription factor E3 [Homo sapiens]                      35   0.24 
gi|39995071 exonuclease 1 isoform b [Homo sapiens]                     35   0.24 

>gi|55769554 protein tyrosine phosphatase, receptor type, f
           polypeptide (PTPRF), interacting protein (liprin), alpha
           4 [Homo sapiens]
          Length = 701

 Score = 1402 bits (3628), Expect = 0.0
 Identities = 701/701 (100%), Positives = 701/701 (100%)

Query: 1   MGSAADVRFSLGTTTHAPPGVHRRYSALREESAKDWETSPLPGMLAPAAGPAFDSDPEIS 60
           MGSAADVRFSLGTTTHAPPGVHRRYSALREESAKDWETSPLPGMLAPAAGPAFDSDPEIS
Sbjct: 1   MGSAADVRFSLGTTTHAPPGVHRRYSALREESAKDWETSPLPGMLAPAAGPAFDSDPEIS 60

Query: 61  DVDEDEPGGLVGSADVVSPSGHSDAQTLAMMLQEQLDAINEEIRMIQEEKESTELRAEEI 120
           DVDEDEPGGLVGSADVVSPSGHSDAQTLAMMLQEQLDAINEEIRMIQEEKESTELRAEEI
Sbjct: 61  DVDEDEPGGLVGSADVVSPSGHSDAQTLAMMLQEQLDAINEEIRMIQEEKESTELRAEEI 120

Query: 121 ETRVTSGSMEALNLKQLRKRGSIPTSLTALSLASASPPLSGRSTPKLTSRSAAQDLDRMG 180
           ETRVTSGSMEALNLKQLRKRGSIPTSLTALSLASASPPLSGRSTPKLTSRSAAQDLDRMG
Sbjct: 121 ETRVTSGSMEALNLKQLRKRGSIPTSLTALSLASASPPLSGRSTPKLTSRSAAQDLDRMG 180

Query: 181 VMTLPSDLRKHRRKLLSPVSREENREDKATIKCETSPPSSPRTLRLEKLGHPALSQEEGK 240
           VMTLPSDLRKHRRKLLSPVSREENREDKATIKCETSPPSSPRTLRLEKLGHPALSQEEGK
Sbjct: 181 VMTLPSDLRKHRRKLLSPVSREENREDKATIKCETSPPSSPRTLRLEKLGHPALSQEEGK 240

Query: 241 SALEDQGSNPSSSNSSQDSLHKGAKRKGIKSSIGRLFGKKEKGRLIQLSRDGATGHVLLT 300
           SALEDQGSNPSSSNSSQDSLHKGAKRKGIKSSIGRLFGKKEKGRLIQLSRDGATGHVLLT
Sbjct: 241 SALEDQGSNPSSSNSSQDSLHKGAKRKGIKSSIGRLFGKKEKGRLIQLSRDGATGHVLLT 300

Query: 301 DSEFSMQEPMVPAKLGTQAEKDRRLKKKHQLLEDARRKGMPFAQWDGPTVVSWLELWVGM 360
           DSEFSMQEPMVPAKLGTQAEKDRRLKKKHQLLEDARRKGMPFAQWDGPTVVSWLELWVGM
Sbjct: 301 DSEFSMQEPMVPAKLGTQAEKDRRLKKKHQLLEDARRKGMPFAQWDGPTVVSWLELWVGM 360

Query: 361 PAWYVAACRANVKSGAIMSALSDTEIQREIGISNALHRLKLRLAIQEMVSLTSPSAPPTS 420
           PAWYVAACRANVKSGAIMSALSDTEIQREIGISNALHRLKLRLAIQEMVSLTSPSAPPTS
Sbjct: 361 PAWYVAACRANVKSGAIMSALSDTEIQREIGISNALHRLKLRLAIQEMVSLTSPSAPPTS 420

Query: 421 RTSSGNVWVTHEEMETLETSTKTDSEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSY 480
           RTSSGNVWVTHEEMETLETSTKTDSEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSY
Sbjct: 421 RTSSGNVWVTHEEMETLETSTKTDSEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSY 480

Query: 481 FMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELEKRREESQH 540
           FMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELEKRREESQH
Sbjct: 481 FMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELEKRREESQH 540

Query: 541 EIKDVLVWTNDQVVHWVQSIGLRDYAGNLHESGVHGALLALDENFDHNTLALILQIPTQN 600
           EIKDVLVWTNDQVVHWVQSIGLRDYAGNLHESGVHGALLALDENFDHNTLALILQIPTQN
Sbjct: 541 EIKDVLVWTNDQVVHWVQSIGLRDYAGNLHESGVHGALLALDENFDHNTLALILQIPTQN 600

Query: 601 TQARQVMEREFNNLLALGTDRKLDDGDDKVFRRAPSWRKRFRPREHHGRGGMLSASAETL 660
           TQARQVMEREFNNLLALGTDRKLDDGDDKVFRRAPSWRKRFRPREHHGRGGMLSASAETL
Sbjct: 601 TQARQVMEREFNNLLALGTDRKLDDGDDKVFRRAPSWRKRFRPREHHGRGGMLSASAETL 660

Query: 661 PAGFRVSTLGTLQPPPAPPKKIMPEAHSHYLYGHMLSAFRD 701
           PAGFRVSTLGTLQPPPAPPKKIMPEAHSHYLYGHMLSAFRD
Sbjct: 661 PAGFRVSTLGTLQPPPAPPKKIMPEAHSHYLYGHMLSAFRD 701


>gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens]
          Length = 1257

 Score =  892 bits (2306), Expect = 0.0
 Identities = 465/660 (70%), Positives = 537/660 (81%), Gaps = 27/660 (4%)

Query: 20   GVHRRYSALREESAKDWETSPLPGMLAPAAGPAFDSDPEISDVDEDEPGGLVGSADVVSP 79
            GV R    ++     +W  +   G+L+      F+SD E+SD+D+D+   +  S D++SP
Sbjct: 584  GVRRDEPKVKSLGDHEWNRTQQIGVLS---SHPFESDTEMSDIDDDDRETIFSSMDLLSP 640

Query: 80   SGHSDAQTLAMMLQEQLDAINEEIRMIQEEKESTELRAEEIETRVTSGSMEALNLKQLRK 139
            SGHSDAQTLAMMLQEQLDAIN+EIR+IQEEKESTELRAEEIE RV S S+E LNL ++  
Sbjct: 641  SGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHP 700

Query: 140  RGSIPTSLTALSLASASPPLSGRSTPKLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLSPV 199
              SI  S+TA SLAS+SPP SG STPKLT RS A+++DRMGVMTLPSDLRKHRRK+   V
Sbjct: 701  GTSITASVTASSLASSSPP-SGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIA--V 757

Query: 200  SREENREDKATIKCETSPPSSPRTLRLEKLGHPALSQEEGKSAL----EDQGSNPSSSNS 255
              E+ REDKATIKCETSPP +PR LR+     P+    + +S+L    E +     S+NS
Sbjct: 758  VEEDGREDKATIKCETSPPPTPRALRMTHT-LPSSYHNDARSSLSVSLEPESLGLGSANS 816

Query: 256  SQDSLHKGAKRKGIKSSIGRLFGKKEKGRLIQLSRDGATGHVLLTDSEFSMQEPMVPAKL 315
            SQDSLHK  K+KGIKSSIGRLFGKKEK RL QL            ++E + QE +   KL
Sbjct: 817  SQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRG--------FMETEAAAQESLGLGKL 868

Query: 316  GTQAEKDRRLKKKHQLLEDARRKGMPFAQWDGPTVVSWLELWVGMPAWYVAACRANVKSG 375
            GTQAEKDRRLKKKH+LLE+ARRKG+PFAQWDGPTVV+WLELW+GMPAWYVAACRANVKSG
Sbjct: 869  GTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSG 928

Query: 376  AIMSALSDTEIQREIGISNALHRLKLRLAIQEMVSLTSPSAPPTSRTSSGNVWVTHEEME 435
            AIMSALSDTEIQREIGISN LHRLKLRLAIQEMVSLTSPSAPPTSRT SGNVWVTHEEME
Sbjct: 929  AIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEME 988

Query: 436  TLETSTKT-DSEEGSWAQ------TLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDA 488
             L    KT +SEEGSWAQ      TLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDA
Sbjct: 989  NLAAPAKTKESEEGSWAQCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDA 1048

Query: 489  RMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELEKRREESQHEIKDVLVW 548
            RMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELE+RRE SQHEIKDVLVW
Sbjct: 1049 RMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVW 1108

Query: 549  TNDQVVHWVQSIGLRDYAGNLHESGVHGALLALDENFDHNTLALILQIPTQNTQARQVME 608
            +ND+V+ W+Q+IGLR+YA N+ ESGVHG+L+ALDENFD+++LAL+LQIPTQNTQARQ++E
Sbjct: 1109 SNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILE 1168

Query: 609  REFNNLLALGTDRKLDDGDDKVFRRAPSWRKRFRPREHHGRGGMLSASAETLPAGFRVST 668
            RE+NNLLALGT+R+LD+ DDK FRR  +WR++F PRE HG   M+  S+ETLPAGFR++T
Sbjct: 1169 REYNNLLALGTERRLDESDDKNFRRGSTWRRQFPPREVHGI-SMMPGSSETLPAGFRLTT 1227


>gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sapiens]
          Length = 1202

 Score =  793 bits (2049), Expect = 0.0
 Identities = 440/711 (61%), Positives = 523/711 (73%), Gaps = 77/711 (10%)

Query: 1    MGSAADVRFSLG---TTTHAPPGVHRR-----YSALREESAK-------DWETSPLPGML 45
            +GS  D RF +    T +++   V RR      +ALR+E +K       DWE +    +L
Sbjct: 528  LGSVPDFRFPMADGHTDSYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVL 587

Query: 46   APAAGPAFDSDPEISDVDEDEPGGLVGSADVVSPSGHSDAQTLAMMLQEQLDAINEEIRM 105
            A  A  AF+SD ++SD  ED+   L+ S D++SPSG +DA TLAMMLQEQLDAIN+EIR+
Sbjct: 588  ANVA-QAFESDADVSD-GEDDRDTLLSSVDLLSPSGQADAHTLAMMLQEQLDAINKEIRL 645

Query: 106  IQEEKESTELRAEEIETRVTSGSMEALNLKQLRKRGSIPTSLTALSLASASPPLSGRSTP 165
            IQEEKE+TE RAEEIE+RV SGS++  NL + R   SIP    A SLAS+SPP SGRSTP
Sbjct: 646  IQEEKENTEQRAEEIESRVGSGSLD--NLGRFRSMSSIPP-YPASSLASSSPPGSGRSTP 702

Query: 166  KLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLSPVSREENREDKATIKCETSPPSSPRTLR 225
            +    S A+++DR+GVMTL             P SREE R+DK TIKCETSPPSSPR LR
Sbjct: 703  RRIPHSPAREVDRLGVMTL------------LPPSREEVRDDKTTIKCETSPPSSPRALR 750

Query: 226  LEKLGHPAL---SQEEGKSALEDQGS------NPSSSNSSQDSLHKGAKRKGIKSSIGRL 276
            L++L   AL   S E+ +      GS      NPSSSNSSQDSLHK  K+KGIKSSIGRL
Sbjct: 751  LDRLHKGALHTVSHEDIRDIRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRL 810

Query: 277  FGKKEKGRLIQLSRDGATGHVLLTDSEFSMQEPMVPAKLGTQAEKDRRLKKKHQLLEDAR 336
            FGKKEKGR  Q  ++ A G   +++++ S Q+ +  +KLG QAEK+R+L+KKH+LLE+AR
Sbjct: 811  FGKKEKGRPGQTGKE-ALGQAGVSETDNSSQDALGLSKLGGQAEKNRKLQKKHELLEEAR 869

Query: 337  RKGMPFAQWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNAL 396
            R+G+PFAQWDGPTVV WLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISN L
Sbjct: 870  RQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPL 929

Query: 397  HRLKLRLAIQEMVSLTSPSAPPTSRTSSGNVWVTHEEMETLETSTKTDSEEGSWAQTLAY 456
            HRLKLRLAIQE++SLTSPSAPPTSRT                              TLAY
Sbjct: 930  HRLKLRLAIQEIMSLTSPSAPPTSRT------------------------------TLAY 959

Query: 457  GDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQY 516
            GDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLR  LKMVDSFHR S Q 
Sbjct: 960  GDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQC 1019

Query: 517  GIMCLKRLNYDRKELEKRREESQHEIKDVLVWTNDQVVHWVQSIGLRDYAGNLHESGVHG 576
            GIMCL+RLNYDRKELE++REESQ EIKDVLVW+ND+V+ W+ SIGL++YA NL ESGVHG
Sbjct: 1020 GIMCLRRLNYDRKELERKREESQSEIKDVLVWSNDRVIRWILSIGLKEYANNLIESGVHG 1079

Query: 577  ALLALDENFDHNTLALILQIPTQNTQARQVMEREFNNLLALGTDRKLDDGDDKVFRRAPS 636
            ALLALDE FD + LAL+LQIPTQNTQAR V+EREFNNLL +GTDR+ D+ DDK FRRAPS
Sbjct: 1080 ALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLVMGTDRRFDEDDDKSFRRAPS 1139

Query: 637  WRKRFRPREHHGRGGMLSASAETLPAGFRVSTLGTLQPPPAPPKKIMPEAH 687
            WRK+FRP++     G+ + SAETLPA FRV++  ++  P   PKK+  + +
Sbjct: 1140 WRKKFRPKDIR---GLAAGSAETLPANFRVTS--SMSSPSMQPKKMQMDGN 1185


>gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo
            sapiens]
          Length = 1185

 Score =  793 bits (2048), Expect = 0.0
 Identities = 440/706 (62%), Positives = 521/706 (73%), Gaps = 77/706 (10%)

Query: 1    MGSAADVRFSLG---TTTHAPPGVHRR-----YSALREESAK-------DWETSPLPGML 45
            +GS  D RF +    T +++   V RR      +ALR+E +K       DWE +    +L
Sbjct: 528  LGSVPDFRFPMADGHTDSYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVL 587

Query: 46   APAAGPAFDSDPEISDVDEDEPGGLVGSADVVSPSGHSDAQTLAMMLQEQLDAINEEIRM 105
            A  A  AF+SD ++SD  ED+   L+ S D++SPSG +DA TLAMMLQEQLDAIN+EIR+
Sbjct: 588  ANVA-QAFESDADVSD-GEDDRDTLLSSVDLLSPSGQADAHTLAMMLQEQLDAINKEIRL 645

Query: 106  IQEEKESTELRAEEIETRVTSGSMEALNLKQLRKRGSIPTSLTALSLASASPPLSGRSTP 165
            IQEEKE+TE RAEEIE+RV SGS++  NL + R   SIP    A SLAS+SPP SGRSTP
Sbjct: 646  IQEEKENTEQRAEEIESRVGSGSLD--NLGRFRSMSSIPP-YPASSLASSSPPGSGRSTP 702

Query: 166  KLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLSPVSREENREDKATIKCETSPPSSPRTLR 225
            +    S A+++DR+GVMTL             P SREE R+DK TIKCETSPPSSPR LR
Sbjct: 703  RRIPHSPAREVDRLGVMTL------------LPPSREEVRDDKTTIKCETSPPSSPRALR 750

Query: 226  LEKLGHPAL---SQEEGKSALEDQGS------NPSSSNSSQDSLHKGAKRKGIKSSIGRL 276
            L++L   AL   S E+ +      GS      NPSSSNSSQDSLHK  K+KGIKSSIGRL
Sbjct: 751  LDRLHKGALHTVSHEDIRDIRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRL 810

Query: 277  FGKKEKGRLIQLSRDGATGHVLLTDSEFSMQEPMVPAKLGTQAEKDRRLKKKHQLLEDAR 336
            FGKKEKGR  Q  ++ A G   +++++ S Q+ +  +KLG QAEK+R+L+KKH+LLE+AR
Sbjct: 811  FGKKEKGRPGQTGKE-ALGQAGVSETDNSSQDALGLSKLGGQAEKNRKLQKKHELLEEAR 869

Query: 337  RKGMPFAQWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNAL 396
            R+G+PFAQWDGPTVV WLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISN L
Sbjct: 870  RQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPL 929

Query: 397  HRLKLRLAIQEMVSLTSPSAPPTSRTSSGNVWVTHEEMETLETSTKTDSEEGSWAQTLAY 456
            HRLKLRLAIQE++SLTSPSAPPTSRT                              TLAY
Sbjct: 930  HRLKLRLAIQEIMSLTSPSAPPTSRT------------------------------TLAY 959

Query: 457  GDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQY 516
            GDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLR  LKMVDSFHR S Q 
Sbjct: 960  GDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQC 1019

Query: 517  GIMCLKRLNYDRKELEKRREESQHEIKDVLVWTNDQVVHWVQSIGLRDYAGNLHESGVHG 576
            GIMCL+RLNYDRKELE++REESQ EIKDVLVW+ND+V+ W+ SIGL++YA NL ESGVHG
Sbjct: 1020 GIMCLRRLNYDRKELERKREESQSEIKDVLVWSNDRVIRWILSIGLKEYANNLIESGVHG 1079

Query: 577  ALLALDENFDHNTLALILQIPTQNTQARQVMEREFNNLLALGTDRKLDDGDDKVFRRAPS 636
            ALLALDE FD + LAL+LQIPTQNTQAR V+EREFNNLL +GTDR+ D+ DDK FRRAPS
Sbjct: 1080 ALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLVMGTDRRFDEDDDKSFRRAPS 1139

Query: 637  WRKRFRPREHHGRGGMLSASAETLPAGFRVSTLGTLQPPPAPPKKI 682
            WRK+FRP++     G+ + SAETLPA FRV++  ++  P   PKK+
Sbjct: 1140 WRKKFRPKDIR---GLAAGSAETLPANFRVTS--SMSSPSMQPKKM 1180


>gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]
          Length = 1194

 Score =  731 bits (1888), Expect = 0.0
 Identities = 399/699 (57%), Positives = 500/699 (71%), Gaps = 43/699 (6%)

Query: 2    GSAADVRFSLGTT----THAPP--------GVHRRYSALREESAKDWETSPLPGMLAPAA 49
            GSA ++R+S   T     H  P        G   R+S ++EE +KDWE S   G + P  
Sbjct: 511  GSALELRYSQAPTLPSGAHLDPYVAGSGRAGKRGRWSGVKEEPSKDWERSAPAGSIPPPF 570

Query: 50   GPAFDSDPEISDVDEDEPGGLVGSADVVSPSGHSDAQTLAMMLQEQLDAINEEIRMIQEE 109
                D        DE+E  G+ G A+++SPSG +D QTLA+MLQEQL+AIN+EI++IQEE
Sbjct: 571  PGELDGS------DEEEAEGMFG-AELLSPSGQADVQTLAIMLQEQLEAINKEIKLIQEE 623

Query: 110  KESTELRAEEIETRVTSGSMEALNLKQLRKRGSIPTSLTALSLASASPPLSGRSTPKLTS 169
            KE+TE RAEE+E+RV+S  +++L   + R   S+P SLT  +LAS SPP SG STP+L  
Sbjct: 624  KETTEQRAEELESRVSSSGLDSLG--RYRSSCSLPPSLTTSTLASPSPPSSGHSTPRLAP 681

Query: 170  RSAAQDLDRMGVMTLPSDLRKHRRKLLSPVSREENREDKATIKCETSPPSSPRTLRLEKL 229
             S A++          +D   H  K  +   R E       I  +T PP+ PR+ RLE++
Sbjct: 682  PSPARE---------GTDKANHVPKEEAGAPRGEG----PAIPGDTPPPT-PRSARLERM 727

Query: 230  GHPALSQEEGKSALEDQGSNPSSSNSSQDSLHKGAKRKGIKSSIGRLFGKKEKGRLIQLS 289
               AL+ + G  +LED G  P  S  + DSLHK  K+K IKSSIGRLFGKKEKGR+    
Sbjct: 728  TQ-ALALQAG--SLED-GGPPRGSEGTPDSLHKAPKKKSIKSSIGRLFGKKEKGRMGPPG 783

Query: 290  RDGATGHVLLTDSEFSMQEPMVPAKLGTQAEKDRRLKKKHQLLEDARRKGMPFAQWDGPT 349
            RD ++     +D   +  +P+  AKL    +KDRR K+KH+LLE+A R+G+PFA WDGPT
Sbjct: 784  RDSSSLAGTPSDETLAT-DPLGLAKLTGPGDKDRRNKRKHELLEEACRQGLPFAAWDGPT 842

Query: 350  VVSWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNALHRLKLRLAIQEMV 409
            VVSWLELWVGMPAWYVAACRANVKSGAIM+ LSDTEIQREIGISN LHRLKLRLAIQEMV
Sbjct: 843  VVSWLELWVGMPAWYVAACRANVKSGAIMANLSDTEIQREIGISNPLHRLKLRLAIQEMV 902

Query: 410  SLTSPSAPPTSRTSSGNVWVTHEEMETLETSTKTDSEEGSWAQTLAYGDMNHEWIGNEWL 469
            SLTSPSAP +SRTS+GNVW+THEEME+L  +TK +++E SW Q LAYGDMNHEW+GN+WL
Sbjct: 903  SLTSPSAPASSRTSTGNVWMTHEEMESLTATTKPETKEISWEQILAYGDMNHEWVGNDWL 962

Query: 470  PSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRK 529
            PSLGLPQYRSYFME LVDARMLDHL KK+LR  LKMVDSFHR SL YGIMCLKRLNYDRK
Sbjct: 963  PSLGLPQYRSYFMESLVDARMLDHLNKKELRGQLKMVDSFHRVSLHYGIMCLKRLNYDRK 1022

Query: 530  ELEKRREESQHEIKDVLVWTNDQVVHWVQSIGLRDYAGNLHESGVHGALLALDENFDHNT 589
            +LE+RREESQ +I+DV+VW+N++V+ WV  +GL+++A NL ESGVHGALLALDE FD++ 
Sbjct: 1023 DLERRREESQTQIRDVMVWSNERVMGWVSGLGLKEFATNLTESGVHGALLALDETFDYSD 1082

Query: 590  LALILQIPTQNTQARQVMEREFNNLLALGTDRKLDDGDDKVFRRAPSWRKRFRPREHHGR 649
            LAL+LQIPTQN QARQ++E+EF+NL++LGTDR+LD+   K F R+PSWRK FR ++    
Sbjct: 1083 LALLLQIPTQNAQARQLLEKEFSNLISLGTDRRLDEDSAKSFSRSPSWRKMFREKDLR-- 1140

Query: 650  GGMLSASAETLPAGFRVSTLGTLQPPPAPPKKIMPEAHS 688
             G+   SAE LP  FR +  G L  P  P +K+ PE  +
Sbjct: 1141 -GVTPDSAEMLPPNFRSAAAGALGSPGLPLRKLQPEGQT 1178


>gi|157837985 kazrin isoform E [Homo sapiens]
          Length = 775

 Score =  179 bits (453), Expect = 1e-44
 Identities = 148/547 (27%), Positives = 243/547 (44%), Gaps = 85/547 (15%)

Query: 93  QEQLDAINEEIRMIQEEKESTELRAEEIETRVTSGSMEALNLKQLR-KRGSIPTSLTALS 151
           ++ + A+ +E  +++ EK     +A+E     T+   + L+LK  R K      ++   S
Sbjct: 188 EDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQ-LDLKDNRMKELEAELAMAKQS 246

Query: 152 LASASPPLSGRST---PKLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLSPVSREENREDK 208
           LA+ +  +  R +   P  T  +  Q+      + L + +R+ ++ L    S   +  D+
Sbjct: 247 LATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQTLYH--SHPPHPADR 304

Query: 209 ATIKCETSPPSSPRTLRLEKLGHPALSQEEGKSALEDQGSNPSSSNSSQDSLHK------ 262
             ++        P  +             +  +A  D+ S PS  NS +   H       
Sbjct: 305 QAVRVSPCHSRQPSVI------------SDASAAEGDRSSTPSDINSPRHRTHSLCNGDS 352

Query: 263 -GAKRKGIKSSIGRLFG---------KKEKGRLIQLSRDGATGHV-------LLTDSEFS 305
            G  +K + + I +            KKEK     +SR  A G         L  DS+  
Sbjct: 353 PGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRVFARGKQRKSLDPGLFDDSDSQ 412

Query: 306 MQEPMVPAKLGTQAEKDRRLKKKHQLLEDARRKGMPFAQWDGPTVVSWLELWVGMPAWYV 365
                    L    E+  RL++   +      +  P + W   TV +WLE+ + MP  YV
Sbjct: 413 CSPTRQSLSLSEGEEQMDRLQQVELV------RTTPMSHWKAGTVQAWLEVVMAMPM-YV 465

Query: 366 AACRANVKSGAIMSALSDTEIQREIGISNALHRLKLRLAIQEMVSLTSPSAPPTSRTSSG 425
            AC  NVKSG ++ +LSD ++Q  +G+ ++LHR KLRLAI++                  
Sbjct: 466 KACTENVKSGKVLLSLSDEDLQLGLGVCSSLHRRKLRLAIEDY----------------- 508

Query: 426 NVWVTHEEMETLETSTKTDSEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECL 485
                             D+E G      A  +++H W+   WL  +GL QY   F   L
Sbjct: 509 -----------------RDAEAGRSLSKAA--ELDHHWVAKAWLNDIGLSQYSQAFQNHL 549

Query: 486 VDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELEKRREESQHEIKDV 545
           VD RML+ L K+DL  HL +   FH+ S+  GI  L ++N+ R+ L++RR   + +  D 
Sbjct: 550 VDGRMLNSLMKRDLEKHLNVSKKFHQVSILLGIELLYQVNFSREALQERRARCETQNIDP 609

Query: 546 LVWTNDQVVHWVQSIGLRDYAGNLHESGVHGALLALDENFDHNTLALILQIPTQNTQARQ 605
           +VWTN +V+ WV+ I L++YA NL  SGVHGA+L L+  F+   +A  L IP+     R+
Sbjct: 610 VVWTNQRVLKWVRDIDLKEYADNLTNSGVHGAVLVLEPTFNAEAMATALGIPSGKHILRR 669

Query: 606 VMEREFN 612
            +  E +
Sbjct: 670 HLAEEMS 676


>gi|29294627 PTPRF interacting protein binding protein 1 isoform 1
           [Homo sapiens]
          Length = 1005

 Score =  146 bits (368), Expect = 7e-35
 Identities = 141/521 (27%), Positives = 221/521 (42%), Gaps = 84/521 (16%)

Query: 108 EEKESTELRAEEIETRV-----TSGSMEALNLKQLRKRGSIPTSLTALSLASASPPLSGR 162
           EE +   +    ++T++     TS   ++ +L  L+K  S     T    +    P   R
Sbjct: 419 EENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKETIQKTSEDRAPAESR 478

Query: 163 STPKLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLSPVSREENREDKATIKCETSPPSSPR 222
               L  R   QD       T   D     RK+ S   R   +     IK      S+P 
Sbjct: 479 PFGTLPPRPPGQD-------TSMDDNPFGTRKVRSSFGRGFFK-----IKSNKRTASAPN 526

Query: 223 TLRLEKLGHPALSQEEGKSA----LEDQGSNPSSS--NSSQDSLHKGAKRKGIKSSIGRL 276
             R      P L++ E ++A    L    S P  S  NS           K     I +L
Sbjct: 527 LDRKRSASAPTLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKL 586

Query: 277 FGKKEKGRLIQLSRDGATGHVLLTDSEFSMQEPMVPAKLGTQAEKDRRLKKKHQLLEDAR 336
           FGK  + +    + D       +++ EF         + GT+A    RL     L +   
Sbjct: 587 FGKLRRSQSTTFNPDD------MSEPEFK--------RGGTRATAGPRLGWSRDLGQSNS 632

Query: 337 RKGMPFAQWDGPTVVSWL-ELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNA 395
              MPFA+W    V +WL E  +G    Y+ + +  + SG  +   S  ++++E+GI ++
Sbjct: 633 DLDMPFAKWTKEQVCNWLMEQGLGS---YLNSGKHWIASGQTLLQASQQDLEKELGIKHS 689

Query: 396 LHRLKLRLAIQEMVSLTSPSAPPTSRTSSGNVWVTHEEMETLETSTKTDSEEGSWAQTLA 455
           LHR KL+LA+Q + S                      E ET                   
Sbjct: 690 LHRKKLQLALQALGS----------------------EEET------------------N 709

Query: 456 YGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQ 515
           +G ++  W+   WL  +GLPQY++ F E  VD RML ++T  DL + LK+V   H  S++
Sbjct: 710 HGKLDFNWV-TRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDL-LSLKVVSVLHHLSIK 767

Query: 516 YGIMCLKRLNYDRKELEKR-REESQHEIKDVLVWTNDQVVHWVQSIGLRDYAGNLHESGV 574
             I  L+  N++   L +R  +E+     +V  WTN +V+ W++S+ L +YA NL  SGV
Sbjct: 768 RAIQVLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGV 827

Query: 575 HGALLALDENFDHNTLALILQIPTQNTQARQVMEREFNNLL 615
           HG L+ L+  F+  T+A +L IP   T  R+ +   FN L+
Sbjct: 828 HGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLI 868


>gi|170784854 PTPRF interacting protein, binding protein 2 (liprin
           beta 2) [Homo sapiens]
          Length = 876

 Score =  137 bits (345), Expect = 3e-32
 Identities = 96/301 (31%), Positives = 144/301 (47%), Gaps = 45/301 (14%)

Query: 316 GTQAEKDRRLKKKHQLLEDARRKGMPFAQWDGPTVVSWLELWVGMPAWYVAACRANVKSG 375
           G +A    RL +             PFAQW    V +WLE + G+ A YV   R  V SG
Sbjct: 529 GLRATAGPRLSRTRDSKGQKSDANAPFAQWSTERVCAWLEDF-GL-AQYVIFARQWVSSG 586

Query: 376 AIMSALSDTEIQREIGISNALHRLKLRLAIQEMVSLTSPSAPPTSRTSSGNVWVTHEEME 435
             +   +  ++++E+GI + LHR KL LA++ +                           
Sbjct: 587 HTLLTATPQDMEKELGIKHPLHRKKLVLAVKAI--------------------------- 619

Query: 436 TLETSTKTDSEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLT 495
                  T  EE S         ++H W+   WL  +GLPQY+  F E  VD RML +LT
Sbjct: 620 ------NTKQEEKSAL-------LDHIWV-TRWLDDIGLPQYKDQFHESRVDGRMLQYLT 665

Query: 496 KKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELEKR-REESQHEIKDVLVWTNDQVV 554
             DL + LK+    H  S++  I  L    ++   L +R  +ES     +V+ W+N +V+
Sbjct: 666 VNDL-LFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQWSNHRVM 724

Query: 555 HWVQSIGLRDYAGNLHESGVHGALLALDENFDHNTLALILQIPTQNTQARQVMEREFNNL 614
            W++S+ L +YA NL  SGVHG L+ L+  F  +TLA++L IP Q T  R+ +  +FN L
Sbjct: 725 EWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNAL 784

Query: 615 L 615
           +
Sbjct: 785 I 785


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
           sapiens]
          Length = 1362

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 74/293 (25%), Positives = 108/293 (36%), Gaps = 56/293 (19%)

Query: 28  LREESAKDWETSPLPGMLAPAAGPAFD--SDPEISDVDEDEPGGLVGSADVVSPSGHSDA 85
           +R     D    P+  + +PA  P     + P  SD   D       S D    S    A
Sbjct: 452 MRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTD---DSEEERA 508

Query: 86  QTLAMMLQEQLDAINEEIRMI---------------QEEKESTELRAEEIETRVTSGSME 130
           Q LA  LQEQL A++E++  +               +E+K+    R EE+E    S + E
Sbjct: 509 QRLAE-LQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKE 567

Query: 131 ALNLKQLRKRGSIPTSLTALSLASASPPLSGRSTPKLTSRSAAQD----LDRMGVMTLPS 186
               K  +   S        S  S   P   +S P  T  S  +D    +       L  
Sbjct: 568 PPPKKTKKNNSSN-------SNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSL 620

Query: 187 DLRKHRRKLLSPV---------SREENREDKATIKCETSPPSSPRTLR------LEKLGH 231
           D+ K   + L  V         S + +  D+  I  ET  PS+ R L       L K   
Sbjct: 621 DINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRK 680

Query: 232 PAL---------SQEEGKSALEDQGSNPSSSNSSQDSLHKGAKRKGIKSSIGR 275
           P           S+ +G S+ E + S+ SSS+ S+DS  + A +   K   GR
Sbjct: 681 PQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGR 733


>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
           sapiens]
          Length = 722

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 70/277 (25%), Positives = 102/277 (36%), Gaps = 56/277 (20%)

Query: 28  LREESAKDWETSPLPGMLAPAAGPAFD--SDPEISDVDEDEPGGLVGSADVVSPSGHSDA 85
           +R     D    P+  + +PA  P     + P  SD   D       S D    S    A
Sbjct: 452 MRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTD---DSEEERA 508

Query: 86  QTLAMMLQEQLDAINEEIRMI---------------QEEKESTELRAEEIETRVTSGSME 130
           Q LA  LQEQL A++E++  +               +E+K+    R EE+E    S + E
Sbjct: 509 QRLAE-LQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKE 567

Query: 131 ALNLKQLRKRGSIPTSLTALSLASASPPLSGRSTPKLTSRSAAQD----LDRMGVMTLPS 186
               K  +   S        S  S   P   +S P  T  S  +D    +       L  
Sbjct: 568 PPPKKTKKNNSSN-------SNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSL 620

Query: 187 DLRKHRRKLLSPV---------SREENREDKATIKCETSPPSSPRTLR------LEKLGH 231
           D+ K   + L  V         S + +  D+  I  ET  PS+ R L       L K   
Sbjct: 621 DINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRK 680

Query: 232 PAL---------SQEEGKSALEDQGSNPSSSNSSQDS 259
           P           S+ +G S+ E + S+ SSS+ S+DS
Sbjct: 681 PQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDS 717


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 53/255 (20%), Positives = 101/255 (39%), Gaps = 19/255 (7%)

Query: 89   AMMLQEQLDAINEEIRMIQEEKESTELRAEEIETRVTSGSMEALNLKQLRKRGSIPTSLT 148
            A +LQ+Q +   E+ R +QE+KE    +  E ET+    ++EA   +QL    S      
Sbjct: 2329 AELLQQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEAERQRQLEM--SAEAERL 2385

Query: 149  ALSLASASPPLSGRSTPKLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLSPVSREENRED- 207
             L +A  S   +         R  A+++      T  +   K        + R+++  D 
Sbjct: 2386 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDA 2445

Query: 208  ----KATIKCETSPPSSPRTLRLEKLGHPALSQEEGKSALEDQGSNPSSSNSSQDSLHKG 263
                +A  + E       +  +L +L    +   + +  L++  +   S  S +DSL + 
Sbjct: 2446 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2505

Query: 264  AKRKGIKSSIGRLFGKKEKGRLIQLSRDGATGHVLLTDSEFSMQEPMVPAKLGTQAEKDR 323
             +           F ++EK +L QL +D       L + +   Q+ M   +    A  + 
Sbjct: 2506 ER-----------FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEE 2554

Query: 324  RLKKKHQLLEDARRK 338
              +++H+  E  RRK
Sbjct: 2555 ARRRQHEAEEGVRRK 2569


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 53/255 (20%), Positives = 101/255 (39%), Gaps = 19/255 (7%)

Query: 89   AMMLQEQLDAINEEIRMIQEEKESTELRAEEIETRVTSGSMEALNLKQLRKRGSIPTSLT 148
            A +LQ+Q +   E+ R +QE+KE    +  E ET+    ++EA   +QL    S      
Sbjct: 2333 AELLQQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEAERQRQLEM--SAEAERL 2389

Query: 149  ALSLASASPPLSGRSTPKLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLSPVSREENRED- 207
             L +A  S   +         R  A+++      T  +   K        + R+++  D 
Sbjct: 2390 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDA 2449

Query: 208  ----KATIKCETSPPSSPRTLRLEKLGHPALSQEEGKSALEDQGSNPSSSNSSQDSLHKG 263
                +A  + E       +  +L +L    +   + +  L++  +   S  S +DSL + 
Sbjct: 2450 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2509

Query: 264  AKRKGIKSSIGRLFGKKEKGRLIQLSRDGATGHVLLTDSEFSMQEPMVPAKLGTQAEKDR 323
             +           F ++EK +L QL +D       L + +   Q+ M   +    A  + 
Sbjct: 2510 ER-----------FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEE 2558

Query: 324  RLKKKHQLLEDARRK 338
              +++H+  E  RRK
Sbjct: 2559 ARRRQHEAEEGVRRK 2573


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 53/255 (20%), Positives = 101/255 (39%), Gaps = 19/255 (7%)

Query: 89   AMMLQEQLDAINEEIRMIQEEKESTELRAEEIETRVTSGSMEALNLKQLRKRGSIPTSLT 148
            A +LQ+Q +   E+ R +QE+KE    +  E ET+    ++EA   +QL    S      
Sbjct: 2329 AELLQQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEAERQRQLEM--SAEAERL 2385

Query: 149  ALSLASASPPLSGRSTPKLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLSPVSREENRED- 207
             L +A  S   +         R  A+++      T  +   K        + R+++  D 
Sbjct: 2386 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDA 2445

Query: 208  ----KATIKCETSPPSSPRTLRLEKLGHPALSQEEGKSALEDQGSNPSSSNSSQDSLHKG 263
                +A  + E       +  +L +L    +   + +  L++  +   S  S +DSL + 
Sbjct: 2446 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2505

Query: 264  AKRKGIKSSIGRLFGKKEKGRLIQLSRDGATGHVLLTDSEFSMQEPMVPAKLGTQAEKDR 323
             +           F ++EK +L QL +D       L + +   Q+ M   +    A  + 
Sbjct: 2506 ER-----------FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEE 2554

Query: 324  RLKKKHQLLEDARRK 338
              +++H+  E  RRK
Sbjct: 2555 ARRRQHEAEEGVRRK 2569


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 53/255 (20%), Positives = 101/255 (39%), Gaps = 19/255 (7%)

Query: 89   AMMLQEQLDAINEEIRMIQEEKESTELRAEEIETRVTSGSMEALNLKQLRKRGSIPTSLT 148
            A +LQ+Q +   E+ R +QE+KE    +  E ET+    ++EA   +QL    S      
Sbjct: 2297 AELLQQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEAERQRQLEM--SAEAERL 2353

Query: 149  ALSLASASPPLSGRSTPKLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLSPVSREENRED- 207
             L +A  S   +         R  A+++      T  +   K        + R+++  D 
Sbjct: 2354 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDA 2413

Query: 208  ----KATIKCETSPPSSPRTLRLEKLGHPALSQEEGKSALEDQGSNPSSSNSSQDSLHKG 263
                +A  + E       +  +L +L    +   + +  L++  +   S  S +DSL + 
Sbjct: 2414 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2473

Query: 264  AKRKGIKSSIGRLFGKKEKGRLIQLSRDGATGHVLLTDSEFSMQEPMVPAKLGTQAEKDR 323
             +           F ++EK +L QL +D       L + +   Q+ M   +    A  + 
Sbjct: 2474 ER-----------FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEE 2522

Query: 324  RLKKKHQLLEDARRK 338
              +++H+  E  RRK
Sbjct: 2523 ARRRQHEAEEGVRRK 2537


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 53/255 (20%), Positives = 101/255 (39%), Gaps = 19/255 (7%)

Query: 89   AMMLQEQLDAINEEIRMIQEEKESTELRAEEIETRVTSGSMEALNLKQLRKRGSIPTSLT 148
            A +LQ+Q +   E+ R +QE+KE    +  E ET+    ++EA   +QL    S      
Sbjct: 2466 AELLQQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEAERQRQLEM--SAEAERL 2522

Query: 149  ALSLASASPPLSGRSTPKLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLSPVSREENRED- 207
             L +A  S   +         R  A+++      T  +   K        + R+++  D 
Sbjct: 2523 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDA 2582

Query: 208  ----KATIKCETSPPSSPRTLRLEKLGHPALSQEEGKSALEDQGSNPSSSNSSQDSLHKG 263
                +A  + E       +  +L +L    +   + +  L++  +   S  S +DSL + 
Sbjct: 2583 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2642

Query: 264  AKRKGIKSSIGRLFGKKEKGRLIQLSRDGATGHVLLTDSEFSMQEPMVPAKLGTQAEKDR 323
             +           F ++EK +L QL +D       L + +   Q+ M   +    A  + 
Sbjct: 2643 ER-----------FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEE 2691

Query: 324  RLKKKHQLLEDARRK 338
              +++H+  E  RRK
Sbjct: 2692 ARRRQHEAEEGVRRK 2706


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 53/255 (20%), Positives = 101/255 (39%), Gaps = 19/255 (7%)

Query: 89   AMMLQEQLDAINEEIRMIQEEKESTELRAEEIETRVTSGSMEALNLKQLRKRGSIPTSLT 148
            A +LQ+Q +   E+ R +QE+KE    +  E ET+    ++EA   +QL    S      
Sbjct: 2307 AELLQQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEAERQRQLEM--SAEAERL 2363

Query: 149  ALSLASASPPLSGRSTPKLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLSPVSREENRED- 207
             L +A  S   +         R  A+++      T  +   K        + R+++  D 
Sbjct: 2364 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDA 2423

Query: 208  ----KATIKCETSPPSSPRTLRLEKLGHPALSQEEGKSALEDQGSNPSSSNSSQDSLHKG 263
                +A  + E       +  +L +L    +   + +  L++  +   S  S +DSL + 
Sbjct: 2424 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2483

Query: 264  AKRKGIKSSIGRLFGKKEKGRLIQLSRDGATGHVLLTDSEFSMQEPMVPAKLGTQAEKDR 323
             +           F ++EK +L QL +D       L + +   Q+ M   +    A  + 
Sbjct: 2484 ER-----------FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEE 2532

Query: 324  RLKKKHQLLEDARRK 338
              +++H+  E  RRK
Sbjct: 2533 ARRRQHEAEEGVRRK 2547


>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
          Length = 4533

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 53/255 (20%), Positives = 101/255 (39%), Gaps = 19/255 (7%)

Query: 89   AMMLQEQLDAINEEIRMIQEEKESTELRAEEIETRVTSGSMEALNLKQLRKRGSIPTSLT 148
            A +LQ+Q +   E+ R +QE+KE    +  E ET+    ++EA   +QL    S      
Sbjct: 2315 AELLQQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEAERQRQLEM--SAEAERL 2371

Query: 149  ALSLASASPPLSGRSTPKLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLSPVSREENRED- 207
             L +A  S   +         R  A+++      T  +   K        + R+++  D 
Sbjct: 2372 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDA 2431

Query: 208  ----KATIKCETSPPSSPRTLRLEKLGHPALSQEEGKSALEDQGSNPSSSNSSQDSLHKG 263
                +A  + E       +  +L +L    +   + +  L++  +   S  S +DSL + 
Sbjct: 2432 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2491

Query: 264  AKRKGIKSSIGRLFGKKEKGRLIQLSRDGATGHVLLTDSEFSMQEPMVPAKLGTQAEKDR 323
             +           F ++EK +L QL +D       L + +   Q+ M   +    A  + 
Sbjct: 2492 ER-----------FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEE 2540

Query: 324  RLKKKHQLLEDARRK 338
              +++H+  E  RRK
Sbjct: 2541 ARRRQHEAEEGVRRK 2555


>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
          Length = 4574

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 53/255 (20%), Positives = 101/255 (39%), Gaps = 19/255 (7%)

Query: 89   AMMLQEQLDAINEEIRMIQEEKESTELRAEEIETRVTSGSMEALNLKQLRKRGSIPTSLT 148
            A +LQ+Q +   E+ R +QE+KE    +  E ET+    ++EA   +QL    S      
Sbjct: 2356 AELLQQQKELAQEQARRLQEDKEQMAQQLAE-ETQGFQRTLEAERQRQLEM--SAEAERL 2412

Query: 149  ALSLASASPPLSGRSTPKLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLSPVSREENRED- 207
             L +A  S   +         R  A+++      T  +   K        + R+++  D 
Sbjct: 2413 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDA 2472

Query: 208  ----KATIKCETSPPSSPRTLRLEKLGHPALSQEEGKSALEDQGSNPSSSNSSQDSLHKG 263
                +A  + E       +  +L +L    +   + +  L++  +   S  S +DSL + 
Sbjct: 2473 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2532

Query: 264  AKRKGIKSSIGRLFGKKEKGRLIQLSRDGATGHVLLTDSEFSMQEPMVPAKLGTQAEKDR 323
             +           F ++EK +L QL +D       L + +   Q+ M   +    A  + 
Sbjct: 2533 ER-----------FIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEE 2581

Query: 324  RLKKKHQLLEDARRK 338
              +++H+  E  RRK
Sbjct: 2582 ARRRQHEAEEGVRRK 2596


>gi|209862789 microtubule associated monoxygenase, calponin and LIM
            domain containing 3 isoform 1 [Homo sapiens]
          Length = 2002

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 48/149 (32%), Positives = 58/149 (38%), Gaps = 9/149 (6%)

Query: 136  QLRKRGSIPTSLTALSLASASPPLSGRSTPKLTSRSA-AQDLDRMGVMTLPSDLRKHRRK 194
            Q +KRG    S  A  LA        +S      R A A+ L RM  M L S   + R+ 
Sbjct: 1576 QPQKRGLPLVSAEAKELAEERMRAREKSVKSQALRDAMARQLSRMQQMELASGAPRPRKA 1635

Query: 195  LLSPVSREENREDKATIKCETSPPSSPRTLRLEKLGHPALSQEEGKSALEDQGSNPSSSN 254
              +P   +E R D  T    T   S   TL+     H A S EE  S   D G    S  
Sbjct: 1636 SSAPSQGKERRPDSPTRP--TLRGSEEPTLK-----HEATS-EEVLSPPSDSGGPDGSFT 1687

Query: 255  SSQDSLHKGAKRKGIKSSIGRLFGKKEKG 283
            SS+ S  K  KR  + S       KK KG
Sbjct: 1688 SSEGSSGKSKKRSSLFSPRRNKKEKKSKG 1716


>gi|29825823 hypothetical protein LOC283987 [Homo sapiens]
          Length = 788

 Score = 38.1 bits (87), Expect = 0.028
 Identities = 23/86 (26%), Positives = 39/86 (45%)

Query: 190 KHRRKLLSPVSREENREDKATIKCETSPPSSPRTLRLEKLGHPALSQEEGKSALEDQGSN 249
           + RR+   P+SR  ++E  +      + P+ P TL+   +  P + +   KS + + G+ 
Sbjct: 579 QRRRRTPEPLSRTGSQEGTSMEGSRPAAPAEPGTLKTSLVATPGIDKLTEKSQVSEDGTL 638

Query: 250 PSSSNSSQDSLHKGAKRKGIKSSIGR 275
            S     Q SL  G+  KG  S   R
Sbjct: 639 RSLEPEPQQSLEDGSPAKGEPSQAWR 664


>gi|32490572 erythrocyte membrane protein band 4.1-like 3 [Homo
           sapiens]
          Length = 1087

 Score = 37.4 bits (85), Expect = 0.048
 Identities = 54/245 (22%), Positives = 100/245 (40%), Gaps = 17/245 (6%)

Query: 46  APAAGPAFDSDPEISDVDEDEPGGLVGSADVVSPSGHSDAQTLAMMLQEQLDAINEEIRM 105
           A +   + D+DP  S  +E +      +AD  + +  SD +  A +  ++L+   ++  +
Sbjct: 671 AASLSASLDNDPSDSSEEETDSERTDTAADGETTATESDQEEDAELKAQELEKTQDD--L 728

Query: 106 IQEEKESTELRAEEIETRVTSGSMEALNLKQLRKRGSIPTSLTALSLASASPPLSGRSTP 165
           ++ +   +EL+   +ET     S +     +  KR  + TS   L+      P+     P
Sbjct: 729 MKHQTNISELKRTFLET-----STDTAVTNEWEKR--LSTSPVRLAARQEDAPMIEPLVP 781

Query: 166 KLTSRSAAQDL-DRMGVMTLPSDLRKHRRKLLSPVSREENREDKATIKCETSPPSSPRTL 224
           + T +S+ + L D   + +L    RK    +    S  ++   K   K E+S   +  T+
Sbjct: 782 EETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSWVQKMETKTESSGIETEPTV 841

Query: 225 RLEKLGHPALSQE----EGKSALEDQGSNPSSSNSSQDSLHKGAKRKGIKSSIGRLF--G 278
               L    + QE    E +  +   G    S+  S D+  + A   GIK   G     G
Sbjct: 842 HHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPA-FTGIKGKEGSALTEG 900

Query: 279 KKEKG 283
            KE+G
Sbjct: 901 AKEEG 905


>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
          Length = 1154

 Score = 37.0 bits (84), Expect = 0.062
 Identities = 47/207 (22%), Positives = 78/207 (37%), Gaps = 25/207 (12%)

Query: 61  DVDEDEPGGLVGSADVVSPSGHSDAQTLAMMLQEQLDAINEEIRMIQEEKESTELRAEEI 120
           ++   EP G +G +D      +S  Q     L+E+   +NEE R +QE   S   +  ++
Sbjct: 204 EMKSSEPSGSLGLSD------YSGLQEELQELRERYHFLNEEYRALQESNSSLTGQLADL 257

Query: 121 ETRVTSGSMEALNLKQLRKRGSIPTSLTALSLASASPPLSGRSTPKLTSRSAAQDLDRM- 179
           E+  T  + E     Q     S  +  + +      P +      +   R A + +  M 
Sbjct: 258 ESERTQRATERWLQSQTLSMTSAESQTSEMDFLEPDPEM---QLLRQQLRDAEEQMHGMK 314

Query: 180 ----GVMTLPSDLRKHRRKLLSPVSREENREDKATIKCETSPPSSPRTLRLEKLGHPALS 235
                +     +L+ HR+     VS EE R  +  +KC     +    LR +   H    
Sbjct: 315 NKCQELCCELEELQHHRQ-----VSEEEQRRLQRELKC-----AQNEVLRFQ-TSHSVTQ 363

Query: 236 QEEGKSALEDQGSNPSSSNSSQDSLHK 262
            EE KS L        +S   Q+ L K
Sbjct: 364 NEELKSRLCTLQKKYDTSQDEQNELLK 390



 Score = 30.4 bits (67), Expect = 5.8
 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 9/84 (10%)

Query: 49  AGPAFDSDPEISDVDEDEPGGLVGSADVVSPSGHSDAQTLAMMLQEQLDAINEEIRMIQE 108
           AG   D   E+  + EDE       A+V +             LQ +L ++ EEI +++ 
Sbjct: 79  AGQHEDDSLELQGLLEDERLASAQQAEVFTKQ--------IQQLQGELRSLREEISLLEH 130

Query: 109 EKESTELRAEEIETRVTSGSMEAL 132
           EKES EL+  E E  +    +++L
Sbjct: 131 EKES-ELKEIEQELHLAQAEIQSL 153


>gi|33147080 STAM binding protein-like 1 [Homo sapiens]
          Length = 436

 Score = 36.6 bits (83), Expect = 0.081
 Identities = 33/120 (27%), Positives = 59/120 (49%), Gaps = 17/120 (14%)

Query: 83  SDAQTLAMMLQEQLDAINEEIRMIQEEKESTELRAEEIETRVTSGSME-----ALNLKQL 137
           ++ + +A M Q+QL++  E+    +++ +  EL   ++ ++ TSG  E     AL+    
Sbjct: 159 AERKRIAQMRQQQLES--EQFLFFEDQLKKQELARGQMRSQQTSGLSEQIDGSALSCFST 216

Query: 138 RKRGSI-------PTSLTALSLASASPPLSGRSTPKLTSRSAAQDL--DRMGVMTLPSDL 188
            +  S+       P    A + AS SPP++   TP  T  SA Q+L  + +  + LP DL
Sbjct: 217 HQNNSLLNVFADQPNKSDATNYASHSPPVNRALTPAAT-LSAVQNLVVEGLRCVVLPEDL 275


>gi|50962882 G patch domain containing 8 [Homo sapiens]
          Length = 1502

 Score = 36.6 bits (83), Expect = 0.081
 Identities = 62/300 (20%), Positives = 101/300 (33%), Gaps = 23/300 (7%)

Query: 44  MLAPAAGPAFDSDPEISDVDEDEPGGLVGSADVVSPSGHSDAQTLAMMLQEQLDAINEEI 103
           M APA+G A       S +++ EPGG  GS      +G S         +       ++ 
Sbjct: 630 MDAPASGSA------CSGLNKQEPGGSHGSE--TEDTGRSLPSKKERSGKSHRHKKKKKH 681

Query: 104 RMIQEEKESTELRAEEIETRVTSGSMEALNLKQLRKRGSIPTSLTALSLASASPPLSGRS 163
           +   + K   +   EE  ++  SG       K+ RK+        +       PP SG  
Sbjct: 682 KKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSP 741

Query: 164 TPKLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLSPVSREENREDKATIKCETSPPSSPR- 222
            P    R A  D  R    +LP++     +K                 K E  P S  R 
Sbjct: 742 APPRRRRRAQDDSQR---RSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRR 798

Query: 223 --TLRLEKLGH---PALSQEEGKSALEDQ--GSNPSSSNSSQDSLHKGAKRKGIKSSIGR 275
             T R  +  H   P+   E+   A   +    +PS  +  ++    G++    +S  GR
Sbjct: 799 AGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGR 858

Query: 276 LFGKKEKGRLIQLSRDGATGHVLLTDSEFSMQEPMVPAKLGTQAEKDRRLKKKHQLLEDA 335
                   R    S   A+       S +S Q           +++ RR  K+    +D+
Sbjct: 859 RHSSHRSSRRSYSSSSDASS----DQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDS 914



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 69/278 (24%), Positives = 96/278 (34%), Gaps = 67/278 (24%)

Query: 108 EEKESTELRAEEIETRVTSGSMEALNLKQLRKRGSIPTSLTALS-LASASPPLSGRSTPK 166
           E  +S E+  E+I  R + G M+A            P S +A S L    P  S  S  +
Sbjct: 610 EPNKSKEVGGEKI-VRSSGGRMDA------------PASGSACSGLNKQEPGGSHGSETE 656

Query: 167 LTSRSAAQDLDRMGVMTLPSDLRKHRRKLLSPVSREENREDKATIKCETSPPSSPRTLRL 226
            T RS     +R G        +KH++        + + E+K++ K E+   S  R  R 
Sbjct: 657 DTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSS-KAESGEKSKKRKKRK 715

Query: 227 EKL--------------------GHPA----------------LSQEEGKSALEDQGSNP 250
            K                     G PA                L  EEG S  +D+G   
Sbjct: 716 RKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGG 775

Query: 251 SSSNSSQDSLHKGAKRKG--IKSSIGRLFGKKEKGRLIQLSR--------DGATGHVLLT 300
           SSS       H G K KG    SS  R  G K   R    S+        D A+ H L  
Sbjct: 776 SSSQD-----HGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQ 830

Query: 301 DSEFSMQEPMVPAKLGTQAEKDR-RLKKKHQLLEDARR 337
            S     E       G++  + R R  ++H     +RR
Sbjct: 831 KSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRR 868


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 47/266 (17%), Positives = 102/266 (38%), Gaps = 39/266 (14%)

Query: 45  LAPAAGP---------AFDSDPEISDVDEDEPGGLVGSADVVSPSGHSDAQTLAMMLQEQ 95
           L PAA P         + +  PE++ V+  E    V S + V        +T      E 
Sbjct: 545 LKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKT------ET 598

Query: 96  LDAINEEIRMIQEEKESTELRAEEIETRVTSGSMEALNLKQLRKRGSIPTSLTALSLASA 155
             ++ E  + +  ++E + ++AE  E + T    +A   K ++K   +            
Sbjct: 599 KPSVTE--KEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVK----------- 645

Query: 156 SPPLSGRSTPKLTSRSAAQDLDRMGVMTLPSDLRKH-RRKLLSPVSREENREDKATIKCE 214
             P   +   +   +  A+  D+  +       ++  ++++   + +EE +E K  +K E
Sbjct: 646 --PEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKE 703

Query: 215 TSPPSSPRTLRLEKLGHPALSQEEGKSALEDQGSNPSSSNSSQDSLHKGA--------KR 266
           T P    + ++ E+       ++E K  ++    +   S++      K A        K 
Sbjct: 704 TPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKE 763

Query: 267 KGIKSSIGRLFGKKEKGRLIQLSRDG 292
           + +K         KEKG++  + ++G
Sbjct: 764 ESVKKDSVAAGKPKEKGKIKVIKKEG 789


>gi|223890252 glutamate receptor interacting protein 1 [Homo sapiens]
          Length = 1076

 Score = 35.4 bits (80), Expect = 0.18
 Identities = 72/318 (22%), Positives = 122/318 (38%), Gaps = 65/318 (20%)

Query: 2    GSAADVRFSLGTTTHAPPGVHRRYSALREESAKDWETSPLPGMLAPAAGPAFDSDPEI-- 59
            GSA D  +    T+    G +         +  DW +    G L+P   P   + P++  
Sbjct: 759  GSAIDTSYGTQGTSFQASGYNF--------NTYDWRSPKQRGSLSPVTKPRSQTYPDVGL 810

Query: 60   --SDVDEDEPGGLVGSADVVSPSGHSDAQTLAMMLQEQLDAINEE--IRMIQEEKE-STE 114
               D D     G  G+AD        +  + A+   E L+   +   +R ++E+ +    
Sbjct: 811  SYEDWDRSTASGFAGAADSAETEQEENFWSQAL---EDLETCGQSGILRELEEKADRRVS 867

Query: 115  LRAEEIETRVTSGSMEALNLKQLRKRGSIPTSLTALSLASASPPLSGRSTPKLTSRSAAQ 174
            LR   +   + SGS  +LN +    R  +    +    +S+ P  S       T+RS   
Sbjct: 868  LRNMTLLATIMSGSTMSLNHEAPTPRSQLGRQASFQERSSSRPHYS------QTTRS--- 918

Query: 175  DLDRMGVMTLPSDLRKHRRKLLSPVSREENREDKATIKCETSPPSSPRTLRLEKLGHPAL 234
                    TLPSD+ +      S   R+  +E K  +        SP  + L K+    L
Sbjct: 919  -------NTLPSDVGRK-----SVTLRKMKQEIKEIM--------SPTPVELHKV---TL 955

Query: 235  SQEEGKSALEDQGSNPSSSNSSQDSLHKGAKRKGIK-SSIGRLFGKKEKGRLIQLSRDGA 293
             ++   S +ED G + +        L KG   K I+ +  G L G K   RL+Q++    
Sbjct: 956  YKD---SDMEDFGFSVADG-----LLEKGVYVKNIRPAGPGDLGGLKPYDRLLQVN---- 1003

Query: 294  TGHVLLTDSEFSMQEPMV 311
              HV   D +  +  P++
Sbjct: 1004 --HVRTRDFDCCLVVPLI 1019


>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
          Length = 2382

 Score = 35.4 bits (80), Expect = 0.18
 Identities = 49/228 (21%), Positives = 98/228 (42%), Gaps = 26/228 (11%)

Query: 61  DVDEDEPGGLVGSADVVSPSGHSDAQTLAMMLQEQLDAIN---EEIRMIQEEKESTELRA 117
           DV ED    +V S  V       D +T+A  +++++  I    E+ ++++EE+E  +   
Sbjct: 531 DVPEDVAQEMVESGYVCE----GDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEE 586

Query: 118 EEIETRVTSGSMEALNLKQLRKRGS-IPT-SLTALSLASASPPLSGRSTPKLTSRSAAQD 175
             ++ +V   S     +KQL    + IPT S T+ S+++   P    +      +     
Sbjct: 587 SSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPS 646

Query: 176 LDRMGVMTLPS--------DLRKHRRKLLSPVSREENREDKATIKCETSPPSSPRTLRLE 227
           +  +   T+ S        + R   ++ +S  S+ E      T+     P   P T++ +
Sbjct: 647 ISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTV-----PGHIPSTVQAQ 701

Query: 228 KLGH---PALSQEEGKSALEDQGSNPSSSNSSQDSLHKGAKRKGIKSS 272
              H   P  S  +G+S  +   S+ +  +SSQ   H   +++GI+ +
Sbjct: 702 SQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHP-QQQQGIQQT 748


>gi|45439327 periplakin [Homo sapiens]
          Length = 1756

 Score = 35.4 bits (80), Expect = 0.18
 Identities = 61/284 (21%), Positives = 108/284 (38%), Gaps = 28/284 (9%)

Query: 64   EDEPGGLVGSADVVSPSGHSDAQTLAMMLQEQLDAINEEIRMIQEEKESTELRAEEIETR 123
            E+EPG        +     + A+++ + L+ Q+D +  E+R +Q  +   E + EE+E  
Sbjct: 1359 EEEPG--------LRAEASAFAESIDVELR-QIDKLRAELRRLQRRRTELERQLEELERE 1409

Query: 124  VTSGSMEALNLKQLRKRGSIPTSLTALSLASASPPLSGRSTPKLTSRSAAQDLDRMGVMT 183
              +       +++L++R      L AL    A        T K+  +   Q      ++ 
Sbjct: 1410 RQARREAEREVQRLQQR------LAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLR 1463

Query: 184  LPSDLRKHRRKLLSPVSREENREDKATIKCETSPP-SSPRTLRLEKLGHPALSQEEGKSA 242
            L  +  +HRR+LL        R+  A  K E         ++++EK G      +  KS+
Sbjct: 1464 LQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEK-GDTEQEIQRLKSS 1522

Query: 243  LEDQGSNPSSSNSSQDSLHKGAKRKGIKSSIG--RLFGKKEKGRLIQLSRDGATGHVLLT 300
            LE++  +    +     L          +S     L   +E+   +QL R          
Sbjct: 1523 LEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERQNLQLETRRL 1582

Query: 301  DSEFSMQ-------EPMVPAKLGTQAEKDRRLKKKHQLLEDARR 337
             SE +M          M  A  GT    D RL    + L+D +R
Sbjct: 1583 QSEINMAATETRDLRNMTVADSGT--NHDSRLWSLERELDDLKR 1624


>gi|8659574 transcription factor E3 [Homo sapiens]
          Length = 575

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 35/137 (25%), Positives = 59/137 (43%), Gaps = 15/137 (10%)

Query: 90  MMLQEQLDAINEEIRMIQEEKESTELRAE-EIETRVTSGSMEALNLKQLRKRGSIPTSLT 148
           ++L+E+  A + ++  +      + + A+ E+E  +   S   L  + L  R S+P SL 
Sbjct: 24  VLLEERRPADSAQLLSLNSLLPESGIVADIELENVLDPDSFYELKSQPLPLRSSLPISLQ 83

Query: 149 AL----SLASASPPLSGRSTPKLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLSPVSREEN 204
           A     +  SAS    G  TP ++S S+++ L R  +M          R       R E 
Sbjct: 84  ATPATPATLSASSSAGGSRTPAMSSSSSSRVLLRQQLM----------RAQAQEQERRER 133

Query: 205 REDKATIKCETSPPSSP 221
           RE  A     +  P+SP
Sbjct: 134 REQAAAAPFPSPAPASP 150


>gi|39995071 exonuclease 1 isoform b [Homo sapiens]
          Length = 846

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 31/105 (29%), Positives = 45/105 (42%), Gaps = 3/105 (2%)

Query: 156 SPPLSGRSTPKLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLSPVSREENR-EDKATIKCE 214
           SPP  G      +      D  R    +  + L++ RRK  SP S  EN   D + +K E
Sbjct: 598 SPPTLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSE 657

Query: 215 TSPPSSPRTLRLEKLGHPALSQEEGKSALEDQGSNPSSSNSSQDS 259
            S       LR       + SQE G+ +L+   ++  S  SS+DS
Sbjct: 658 ESSDDESHPLREGACS--SQSQESGEFSLQSSNASKLSQCSSKDS 700


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,853,685
Number of Sequences: 37866
Number of extensions: 1406483
Number of successful extensions: 6043
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 135
Number of HSP's that attempted gapping in prelim test: 5742
Number of HSP's gapped (non-prelim): 380
length of query: 701
length of database: 18,247,518
effective HSP length: 109
effective length of query: 592
effective length of database: 14,120,124
effective search space: 8359113408
effective search space used: 8359113408
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.