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Search of human proteins with 55749779
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55749779 DENN/MADD domain containing 1A isoform 1 [Homo
sapiens]
(1009 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55749779 DENN/MADD domain containing 1A isoform 1 [Homo sapiens] 2041 0.0
gi|55749789 DENN/MADD domain containing 1A isoform 2 [Homo sapiens] 1070 0.0
gi|218563726 DENN/MADD domain containing 1B isoform 1 [Homo sapi... 635 0.0
gi|188219541 DENN/MADD domain containing 1B isoform 2 [Homo sapi... 550 e-156
gi|113205087 DENN/MADD domain containing 1C [Homo sapiens] 473 e-133
gi|154813195 DENN/MADD domain containing 2A [Homo sapiens] 162 1e-39
gi|47132529 suppression of tumorigenicity 5 isoform 1 [Homo sapi... 152 2e-36
gi|47132532 suppression of tumorigenicity 5 isoform 1 [Homo sapi... 152 2e-36
gi|21264614 suppression of tumorigenicity 5 isoform 2 [Homo sapi... 152 2e-36
gi|121949817 DENN/MADD domain containing 2C [Homo sapiens] 150 6e-36
gi|21361991 DENN/MADD domain containing 2D [Homo sapiens] 147 5e-35
gi|44889475 RAB6 interacting protein 1 [Homo sapiens] 88 4e-17
gi|122891862 DENN/MADD domain containing 5B [Homo sapiens] 79 2e-14
gi|94818781 DENN/MADD domain containing 4C [Homo sapiens] 79 2e-14
gi|221307568 DENN/MADD domain containing 4A isoform 1 [Homo sapi... 78 4e-14
gi|221307566 DENN/MADD domain containing 4A isoform 2 [Homo sapi... 78 4e-14
gi|50345870 DENN/MADD domain containing 3 [Homo sapiens] 77 1e-13
gi|29788755 SET binding factor 2 [Homo sapiens] 74 5e-13
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 71 6e-12
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 71 6e-12
gi|239735519 SET binding factor 1 [Homo sapiens] 70 1e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni... 69 2e-11
gi|148922920 DENN/MADD domain containing 4B [Homo sapiens] 69 3e-11
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 67 6e-11
gi|160707881 formin 2 [Homo sapiens] 67 1e-10
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 66 2e-10
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 66 2e-10
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 65 2e-10
gi|210032580 SET domain containing 1B [Homo sapiens] 64 5e-10
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 64 7e-10
>gi|55749779 DENN/MADD domain containing 1A isoform 1 [Homo sapiens]
Length = 1009
Score = 2041 bits (5288), Expect = 0.0
Identities = 1009/1009 (100%), Positives = 1009/1009 (100%)
Query: 1 MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD 60
MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD
Sbjct: 1 MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD 60
Query: 61 SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT 120
SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT
Sbjct: 61 SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT 120
Query: 121 TKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVD 180
TKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVD
Sbjct: 121 TKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVD 180
Query: 181 VNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCC 240
VNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCC
Sbjct: 181 VNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCC 240
Query: 241 APMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKV 300
APMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKV
Sbjct: 241 APMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKV 300
Query: 301 STTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQ 360
STTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQ
Sbjct: 301 STTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQ 360
Query: 361 LQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVRKGSGAILNTVK 420
LQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVRKGSGAILNTVK
Sbjct: 361 LQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVRKGSGAILNTVK 420
Query: 421 TKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCAPTPEEQLPKTAPSPLVEAKD 480
TKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCAPTPEEQLPKTAPSPLVEAKD
Sbjct: 421 TKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCAPTPEEQLPKTAPSPLVEAKD 480
Query: 481 PKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRRTSVPSPEQPQPYRTLRESDSAE 540
PKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRRTSVPSPEQPQPYRTLRESDSAE
Sbjct: 481 PKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRRTSVPSPEQPQPYRTLRESDSAE 540
Query: 541 GDEAESPEQQVRKSTGPVPAPPDRAASIDLLEDVFSNLDMEAALQPLGQAKSLEDLRAPK 600
GDEAESPEQQVRKSTGPVPAPPDRAASIDLLEDVFSNLDMEAALQPLGQAKSLEDLRAPK
Sbjct: 541 GDEAESPEQQVRKSTGPVPAPPDRAASIDLLEDVFSNLDMEAALQPLGQAKSLEDLRAPK 600
Query: 601 DLREQPGTFDYQRLDLGGSERSRGVTVALKLTHPYNKLWSLGQDDMAIPSKPPAASPEKP 660
DLREQPGTFDYQRLDLGGSERSRGVTVALKLTHPYNKLWSLGQDDMAIPSKPPAASPEKP
Sbjct: 601 DLREQPGTFDYQRLDLGGSERSRGVTVALKLTHPYNKLWSLGQDDMAIPSKPPAASPEKP 660
Query: 661 SALLGNSLALPRRPQNRDSILNPSDKEEVPTPTLGSITIPRPQGRKTPELGIVPPPPIPR 720
SALLGNSLALPRRPQNRDSILNPSDKEEVPTPTLGSITIPRPQGRKTPELGIVPPPPIPR
Sbjct: 661 SALLGNSLALPRRPQNRDSILNPSDKEEVPTPTLGSITIPRPQGRKTPELGIVPPPPIPR 720
Query: 721 PAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPGVVPQGPTELLQPLSPGPGAAGTSSD 780
PAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPGVVPQGPTELLQPLSPGPGAAGTSSD
Sbjct: 721 PAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPGVVPQGPTELLQPLSPGPGAAGTSSD 780
Query: 781 ALLALLDPLSTAWSGSTLPSRPATPNVATPFTPQFSFPPAGTPTPFPQPPLNPFVPSMPA 840
ALLALLDPLSTAWSGSTLPSRPATPNVATPFTPQFSFPPAGTPTPFPQPPLNPFVPSMPA
Sbjct: 781 ALLALLDPLSTAWSGSTLPSRPATPNVATPFTPQFSFPPAGTPTPFPQPPLNPFVPSMPA 840
Query: 841 APPTLPLVSTPAGPFGAPPASLGPAFASGLLLSSAGFCAPHRSQPNLSALSMPNLFGQMP 900
APPTLPLVSTPAGPFGAPPASLGPAFASGLLLSSAGFCAPHRSQPNLSALSMPNLFGQMP
Sbjct: 841 APPTLPLVSTPAGPFGAPPASLGPAFASGLLLSSAGFCAPHRSQPNLSALSMPNLFGQMP 900
Query: 901 MGTHTSPLQPLGPPAVAPSRIRTLPLARSSARAAETKQGLALRPGDPPLLPPRPPQGLEP 960
MGTHTSPLQPLGPPAVAPSRIRTLPLARSSARAAETKQGLALRPGDPPLLPPRPPQGLEP
Sbjct: 901 MGTHTSPLQPLGPPAVAPSRIRTLPLARSSARAAETKQGLALRPGDPPLLPPRPPQGLEP 960
Query: 961 TLQPSAPQQARDPFEDLLQKTKQDVSPSPALAPAPDSVEQLRKQWETFE 1009
TLQPSAPQQARDPFEDLLQKTKQDVSPSPALAPAPDSVEQLRKQWETFE
Sbjct: 961 TLQPSAPQQARDPFEDLLQKTKQDVSPSPALAPAPDSVEQLRKQWETFE 1009
>gi|55749789 DENN/MADD domain containing 1A isoform 2 [Homo sapiens]
Length = 559
Score = 1070 bits (2766), Expect = 0.0
Identities = 526/526 (100%), Positives = 526/526 (100%)
Query: 1 MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD 60
MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD
Sbjct: 1 MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD 60
Query: 61 SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT 120
SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT
Sbjct: 61 SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT 120
Query: 121 TKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVD 180
TKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVD
Sbjct: 121 TKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVD 180
Query: 181 VNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCC 240
VNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCC
Sbjct: 181 VNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCC 240
Query: 241 APMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKV 300
APMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKV
Sbjct: 241 APMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKV 300
Query: 301 STTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQ 360
STTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQ
Sbjct: 301 STTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQ 360
Query: 361 LQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVRKGSGAILNTVK 420
LQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVRKGSGAILNTVK
Sbjct: 361 LQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVRKGSGAILNTVK 420
Query: 421 TKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCAPTPEEQLPKTAPSPLVEAKD 480
TKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCAPTPEEQLPKTAPSPLVEAKD
Sbjct: 421 TKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCAPTPEEQLPKTAPSPLVEAKD 480
Query: 481 PKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRRTSVPSPEQ 526
PKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRRTSVPSPEQ
Sbjct: 481 PKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRRTSVPSPEQ 526
>gi|218563726 DENN/MADD domain containing 1B isoform 1 [Homo
sapiens]
Length = 755
Score = 635 bits (1637), Expect = 0.0
Identities = 355/699 (50%), Positives = 461/699 (65%), Gaps = 40/699 (5%)
Query: 1 MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD 60
M R K NP+ TF++ ++V + DP V +FPED+ DQE+LQ++ KFCFPF V+
Sbjct: 1 MDCRTKANPDRTFDLVLKVKCHASEN--EDPVVLWKFPEDFGDQEILQSVPKFCFPFDVE 58
Query: 61 SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT 120
++ +QVGQ+FTFVLTDI+SKQRFGFCRL+SG C CILSYLPWFEV+YKLLN LADY
Sbjct: 59 RVSQNQVGQHFTFVLTDIESKQRFGFCRLTSGGTICLCILSYLPWFEVYYKLLNTLADYL 118
Query: 121 TKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVD 180
K EN NE L +L+ P+P V+LSVHSYF PD LP+IPE+RNLTEYFVAVD
Sbjct: 119 AKELENDLNETLRSLYNHPVPKANTPVNLSVHSYFIAPDVTGLPTIPESRNLTEYFVAVD 178
Query: 181 VNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCC 240
VNNML LYASML+ERRI+II SKLSTLTACIHGSAA+LYPMYWQH+YIPVLPPHLLDYCC
Sbjct: 179 VNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYPMYWQHIYIPVLPPHLLDYCC 238
Query: 241 APMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKV 300
APMPYLIGIH SL+E+V+N +L+DVV+LNVDTNTLE+PF DL +LP+DV+S+LKN+LKK
Sbjct: 239 APMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTLESPFSDLNNLPSDVVSALKNKLKKQ 298
Query: 301 STTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQ 360
ST TGDGVARAFL+AQAA FGSYR+AL+ +P EPITFCEE+FV H RS M+QFL+ A
Sbjct: 299 STATGDGVARAFLRAQAALFGSYRDALRYKPGEPITFCEESFVKH-RSSVMKQFLETAIN 357
Query: 361 LQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSD-KLYHQWLSTVRKGSGAILNTV 419
LQLFKQFIDGRL LN+G GFSDVFEEEI G + G + + Y QW+ TV+KG GA+ NT
Sbjct: 358 LQLFKQFIDGRLAKLNAGRGFSDVFEEEITSGGFCGGNPRSYQQWVHTVKKG-GALFNTA 416
Query: 420 KTKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCAPTPEEQLPKTAPSPLVEAK 479
TKA PA++T YKFAK+HAK+G+KEVK++LK K+ E+ + Q +P+ +
Sbjct: 417 MTKATPAVRTAYKFAKNHAKLGLKEVKSKLKHKENEEDYGTCSSSVQY-----TPVYKLH 471
Query: 480 DPKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRRTSVPSPEQPQPYRTLRESDSA 539
+ K + Q R +KRP ++ +G ++ E + S
Sbjct: 472 NEKGGNSEKR---KLAQAR------LKRPLKSL--DG---ALYDDEDDDDIERASKLSSE 517
Query: 540 EGDEAESPEQQVRKSTGPVPAPPDRAASIDLLEDVFSNLDMEAALQ-PLGQAKSLEDLRA 598
+G+EA + + S P + +DLL ++ L ++ Q L AKSL+ R+
Sbjct: 518 DGEEASAYLYESDDSVETRVKTP-YSGEMDLLGEILDTLSTHSSDQGKLAAAKSLDFFRS 576
Query: 599 PKDLREQPGTFDYQRLDLGGSERSRGVTVALKLTHPYNKLWSLGQDDMAIPSK--PPAAS 656
D+ DY+ + + + + + W+LGQDD A+ K PP+
Sbjct: 577 MDDI-------DYKPTNKSNAPSENNLAFLCGGSGDQAE-WNLGQDDSALHGKHLPPSPR 628
Query: 657 PEKPSALLGNSLALPRRPQNRDSILNPSDKEEVPTPTLG 695
S+ L +SL + + + + + V PT G
Sbjct: 629 KRVSSSGLTDSLFILKEENSNKHL----GADNVSDPTSG 663
>gi|188219541 DENN/MADD domain containing 1B isoform 2 [Homo
sapiens]
Length = 426
Score = 550 bits (1417), Expect = e-156
Identities = 276/425 (64%), Positives = 328/425 (77%), Gaps = 24/425 (5%)
Query: 1 MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD 60
M R K NP+ TF++ ++V + DP V +FPED+ DQE+LQ++ KFCFPF V+
Sbjct: 1 MDCRTKANPDRTFDLVLKVKCHASEN--EDPVVLWKFPEDFGDQEILQSVPKFCFPFDVE 58
Query: 61 SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT 120
++ +QVGQ+FTFVLTDI+SKQRFGFCRL+SG C CILSYLPWFEV+YKLLN LADY
Sbjct: 59 RVSQNQVGQHFTFVLTDIESKQRFGFCRLTSGGTICLCILSYLPWFEVYYKLLNTLADYL 118
Query: 121 TKRQENQWNELLETLHKLPIPDPGVSVHLSV--------------------HSYFTVPDT 160
K EN NE L +L+ P+P V+LSV HSYF PD
Sbjct: 119 AKELENDLNETLRSLYNHPVPKANTPVNLSVNQEIFIACEQVLKDQPALVPHSYFIAPDV 178
Query: 161 RELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYP 220
LP+IPE+RNLTEYFVAVDVNNML LYASML+ERRI+II SKLSTLTACIHGSAA+LYP
Sbjct: 179 TGLPTIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTACIHGSAALLYP 238
Query: 221 MYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFD 280
MYWQH+YIPVLPPHLLDYCCAPMPYLIGIH SL+E+V+N +L+DVV+LNVDTNTLE+PF
Sbjct: 239 MYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLNVDTNTLESPFS 298
Query: 281 DLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEE 340
DL +LP+DV+S+LKN+LKK ST TGDGVARAFL+AQAA FGSYR+AL+ +P EPITFCEE
Sbjct: 299 DLNNLPSDVVSALKNKLKKQSTATGDGVARAFLRAQAALFGSYRDALRYKPGEPITFCEE 358
Query: 341 AFVSHYRSGAMRQFLQNATQLQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEY-AGSDK 399
+FV H RS M+QFL+ A LQLFKQFIDGRL LN+G GFSDVFEEEI G + G DK
Sbjct: 359 SFVKH-RSSVMKQFLETAINLQLFKQFIDGRLAKLNAGRGFSDVFEEEITSGGFCGGKDK 417
Query: 400 LYHQW 404
L + +
Sbjct: 418 LQYDY 422
>gi|113205087 DENN/MADD domain containing 1C [Homo sapiens]
Length = 801
Score = 473 bits (1216), Expect = e-133
Identities = 320/836 (38%), Positives = 430/836 (51%), Gaps = 119/836 (14%)
Query: 1 MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD 60
M SR + F+ + E A P + DP + RQFP D+ DQE +Q + KFCFPF V+
Sbjct: 1 MESRAEGGSPAVFDWFFEAACPAS--LQEDPPILRQFPPDFRDQEAMQMVPKFCFPFDVE 58
Query: 61 SLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYT 120
S Q+FTF LTD+ +RFGFCRL +G +SC CILS+LPWFEVFYKLLN + D
Sbjct: 59 REPPSPAVQHFTFALTDLAGNRRFGFCRLRAGTQSCLCILSHLPWFEVFYKLLNTVGDLL 118
Query: 121 TKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTV----------------------P 158
+ Q + ELL+ L + + P SV L + S TV P
Sbjct: 119 AQDQVTEAEELLQNLFQQSLSGPQASVGLELGSGVTVSSGQGIPPPTRGNSKPLSCFVAP 178
Query: 159 DTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAML 218
D+ LPSIPENRNLTE VAV N++ L+A++L ERR+L+ SKLSTLT+C+H S A+L
Sbjct: 179 DSGRLPSIPENRNLTELVVAVTDENIVGLFAALLAERRVLLTASKLSTLTSCVHASCALL 238
Query: 219 YPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETP 278
YPM W+HV IP LPPHLLDYCCAPMPYLIG+H SL E+VR AL+DVV+LNVD NTLET
Sbjct: 239 YPMRWEHVLIPTLPPHLLDYCCAPMPYLIGVHASLAERVREKALEDVVVLNVDANTLETT 298
Query: 279 FDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFC 338
F+D+Q+LP DV+S L+ RL+KV+ G+GV+R FLKAQA FG YR+AL P +P+TF
Sbjct: 299 FNDVQALPPDVVSLLRLRLRKVALAPGEGVSRLFLKAQALLFGGYRDALVCSPGQPVTFS 358
Query: 339 EEAFVSHYRSGAMRQFLQNATQLQLFKQFIDGRLDLLNSGEGFSDVFEEEI-NMGEYAGS 397
EE F++ ++ F + A LQLFKQFI+ RL+ LN GEGFSD FE+EI G +G+
Sbjct: 359 EEVFLAQKPGAPLQAFHRRAVHLQLFKQFIEARLEKLNKGEGFSDQFEQEITGCGASSGA 418
Query: 398 DKLYHQWLSTVRKGSGAILNTVKTKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKD---I 454
+ Y W ++KG GA+L++VK K PA+K +Y+ AK G+K V++ L KD +
Sbjct: 419 LRSYQLWADNLKKGGGALLHSVKAKTQPAVKNMYR----SAKSGLKGVQSLLMYKDGDSV 474
Query: 455 AENGCAPTPEEQLPKTAPSPLVEAKDPKLREDRRPITVHFGQVRPPRPHVVKRPKSNIA- 513
+ G + +P + ++ +L++ R PIT HFG+ RP RP ++ + +
Sbjct: 475 LQRG----------GSLRAPALPSRSDRLQQ-RLPITQHFGKNRPLRPSRRRQLEEGTSE 523
Query: 514 VEGRRTSVPSPEQ---PQPYRTLRESDSAEGDEAESPEQQVRKSTGPVPAPPDRAASIDL 570
G T SPE P L S G+E +DL
Sbjct: 524 PPGAGTPPLSPEDEGCPWAEEALDSSFLGSGEE------------------------LDL 559
Query: 571 LEDVFSNLDMEAALQPLGQAKSLEDLRAPKDLREQPGTFDYQRLDLGGSERSRGVTVALK 630
L ++ +L M AKS LR + L R DL
Sbjct: 560 LSEILDSLSM--------GAKSAGSLRPSQSLD------CCHRGDLDSC----------- 594
Query: 631 LTHPYNKLWSLGQDDMAIPSKPPAASPEKPSALLGNSLALPRRPQNRDSILNPSDK-EEV 689
+ P W DD +P +P PS +SL ++ S L PS+ +EV
Sbjct: 595 FSLPNIPRWQ--PDDKKLP-EPEPQPLSLPSLQNASSLDATSSSKDSRSQLIPSESDQEV 651
Query: 690 PTPTLGSITIPRPQGRKTPELGIVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRAALS 749
+P+ S P P+ P P+ P L S + D + +
Sbjct: 652 TSPSQSSTASADPSIWGDPK-----PSPLTEPLILHLT------PSHKAAEDSTAQENPT 700
Query: 750 PGLLPGVVPQGPTE---LLQPLSPGPGAAGTSSDALLALLDPLSTAWSGSTLPSRP 802
P L P E +L P P A TS LDP S S +RP
Sbjct: 701 PWLSTAPTEPSPPESPQILAPTKPNFDIAWTSQP-----LDPSSDPSSLEDPRARP 751
>gi|154813195 DENN/MADD domain containing 2A [Homo sapiens]
Length = 1009
Score = 162 bits (410), Expect = 1e-39
Identities = 128/444 (28%), Positives = 212/444 (47%), Gaps = 55/444 (12%)
Query: 5 IKQNPETTFEVYVEVA-YPRTGGTLSDPEVQRQFP----------EDYSDQEVLQTLTKF 53
I+ FE +V V+ + + G PE+ +QFP + DQ L+ + +F
Sbjct: 557 IEYQERQLFEYFVVVSLHKKQAGAAYVPELTQQFPLKLERSFKFMREAEDQ--LKAIPQF 614
Query: 54 CFPFYVDSLTVSQ-VGQNFTFVLTDIDSKQRFGFCR-LSSGAKS-----CFCILSYLPWF 106
CFP D + V Q + F+FVLT D +RFG+CR L G K +CI+S L F
Sbjct: 615 CFPDAKDWVPVQQFTSETFSFVLTGEDGSRRFGYCRRLLPGGKGKRLPEVYCIVSRLGCF 674
Query: 107 EVFYKLLNILADYTTKRQENQ---WNELLETLHKLPIPDPGVSV----HLSVHSYFTVPD 159
+F ++L D KR+ L+ ++ + P P G ++ L +
Sbjct: 675 SLFSRIL----DEVEKRRGISPALVQPLMRSVMEAPFPALGKTILVKNFLPGSGTEVIEL 730
Query: 160 TRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLY 219
R L S E+ + F ++ V +++ ++AS+L ERR++ I KLS L+ C H A++Y
Sbjct: 731 CRPLDSRLEHVDFESLFSSLSVRHLVCVFASLLLERRVIFIADKLSILSKCCHAMVALIY 790
Query: 220 PMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPF 279
P WQH YIPVLPP ++D C+P P+LIG+ S + +R + L++V+++++ +
Sbjct: 791 PFAWQHTYIPVLPPAMVDIVCSPTPFLIGLLSSSLPLLRELPLEEVLVVDLVNSRFLRQM 850
Query: 280 DDLQS-LPNDVISSLKNRLKK-------------------VSTTTGDGVARAFLKAQAAF 319
DD S LP + +L++ L++ S+ + V+ AF++
Sbjct: 851 DDEDSILPRKLQVALEHILEQRNELACEQDEGPLDGRHGPESSPLNEVVSEAFVRFFVEI 910
Query: 320 FGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQLQLFKQFIDGRLDLLNSGE 379
G Y L E T EAF S ++R FL+ + Q+F+ FI R +
Sbjct: 911 VGHYSLFLTSGEREERTLQREAFRKAVSSKSLRHFLEVFMETQMFRGFIQERELRRQDAK 970
Query: 380 GFSDV----FEEEINMGEYAGSDK 399
G +V + E + GE++G +K
Sbjct: 971 GLFEVRAQEYLETLPSGEHSGVNK 994
>gi|47132529 suppression of tumorigenicity 5 isoform 1 [Homo sapiens]
Length = 1137
Score = 152 bits (383), Expect = 2e-36
Identities = 107/379 (28%), Positives = 185/379 (48%), Gaps = 43/379 (11%)
Query: 31 PEVQRQFP-------EDYSDQEVLQTLTKFCFPFYVDSLTVSQVG-QNFTFVLTDIDSKQ 82
PEV QFP + +E L+ + +FCFP D L VS+ + F+F+LT D +
Sbjct: 716 PEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSR 775
Query: 83 RFGFCR--LSSGA----KSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNEL----L 132
RFG+CR L SG +C++S L F +F K+L+ +R+ L +
Sbjct: 776 RFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLD-----EVERRRGISAALVYPFM 830
Query: 133 ETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENR----NLTEYFVAVDVNNMLHLY 188
+L + P P PG ++ + + EL ++R + F + V ++ ++
Sbjct: 831 RSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIF 890
Query: 189 ASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIG 248
AS+L ERR++ + KLSTL++C H A+LYP WQH +IPVLP ++D C P P+L+G
Sbjct: 891 ASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVG 950
Query: 249 IHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQS-LPNDVISSLKNRLKKVS------ 301
+ S + K++ + +++ +++N+ ++ DD + LP + ++L+ L++ +
Sbjct: 951 LLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQD 1010
Query: 302 ---------TTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMR 352
T V+ F++ G Y L + F EAF S ++R
Sbjct: 1011 SDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIR 1070
Query: 353 QFLQNATQLQLFKQFIDGR 371
+FL+ + Q+F FI R
Sbjct: 1071 RFLEVFMESQMFAGFIQDR 1089
Score = 37.4 bits (85), Expect = 0.072
Identities = 34/101 (33%), Positives = 39/101 (38%), Gaps = 20/101 (19%)
Query: 773 GAAGTSSDALLALLDPLSTAWSGSTLPSRPATPNVATPFTPQFSFPPAGTPTPFPQ---- 828
G AG + +A P SGST P P + + S PA P P P+
Sbjct: 340 GVAGVAGEAG----PPPEREGSGSTKPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFE 395
Query: 829 ---------PPLNPFVPS-MPAAPPTLPLVSTPAGPFGAPP 859
P N PS PAAPP LP STPA P P
Sbjct: 396 YEADKNPKSKPSNGLPPSPTPAAPPPLP--STPAPPVTRRP 434
Score = 32.0 bits (71), Expect = 3.0
Identities = 30/117 (25%), Positives = 45/117 (38%), Gaps = 19/117 (16%)
Query: 900 PMGTHTSPLQPLGPPAVAPSRIRTLPLARSSARA----AETKQGLALRPGDPPLLPPRPP 955
P GT + PP ++P R PL+ S A + + + L+ PP P+ P
Sbjct: 21 PRGTLSRSQSVSPPPVLSPPRSPIYPLSDSETSACRYPSHSSSRVLLKDRHPPAPSPQNP 80
Query: 956 QGLEP-TLQPSAPQQA--------------RDPFEDLLQKTKQDVSPSPALAPAPDS 997
Q P T P+ P + RD ++ +Q QDV+ A P S
Sbjct: 81 QDPSPDTSPPTCPFKTASFGYLDRSPSACKRDAQKESVQGAAQDVAGVAACLPLAQS 137
>gi|47132532 suppression of tumorigenicity 5 isoform 1 [Homo sapiens]
Length = 1137
Score = 152 bits (383), Expect = 2e-36
Identities = 107/379 (28%), Positives = 185/379 (48%), Gaps = 43/379 (11%)
Query: 31 PEVQRQFP-------EDYSDQEVLQTLTKFCFPFYVDSLTVSQVG-QNFTFVLTDIDSKQ 82
PEV QFP + +E L+ + +FCFP D L VS+ + F+F+LT D +
Sbjct: 716 PEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSR 775
Query: 83 RFGFCR--LSSGA----KSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNEL----L 132
RFG+CR L SG +C++S L F +F K+L+ +R+ L +
Sbjct: 776 RFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLD-----EVERRRGISAALVYPFM 830
Query: 133 ETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENR----NLTEYFVAVDVNNMLHLY 188
+L + P P PG ++ + + EL ++R + F + V ++ ++
Sbjct: 831 RSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIF 890
Query: 189 ASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIG 248
AS+L ERR++ + KLSTL++C H A+LYP WQH +IPVLP ++D C P P+L+G
Sbjct: 891 ASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVG 950
Query: 249 IHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQS-LPNDVISSLKNRLKKVS------ 301
+ S + K++ + +++ +++N+ ++ DD + LP + ++L+ L++ +
Sbjct: 951 LLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQD 1010
Query: 302 ---------TTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMR 352
T V+ F++ G Y L + F EAF S ++R
Sbjct: 1011 SDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIR 1070
Query: 353 QFLQNATQLQLFKQFIDGR 371
+FL+ + Q+F FI R
Sbjct: 1071 RFLEVFMESQMFAGFIQDR 1089
Score = 37.4 bits (85), Expect = 0.072
Identities = 34/101 (33%), Positives = 39/101 (38%), Gaps = 20/101 (19%)
Query: 773 GAAGTSSDALLALLDPLSTAWSGSTLPSRPATPNVATPFTPQFSFPPAGTPTPFPQ---- 828
G AG + +A P SGST P P + + S PA P P P+
Sbjct: 340 GVAGVAGEAG----PPPEREGSGSTKPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFE 395
Query: 829 ---------PPLNPFVPS-MPAAPPTLPLVSTPAGPFGAPP 859
P N PS PAAPP LP STPA P P
Sbjct: 396 YEADKNPKSKPSNGLPPSPTPAAPPPLP--STPAPPVTRRP 434
Score = 32.0 bits (71), Expect = 3.0
Identities = 30/117 (25%), Positives = 45/117 (38%), Gaps = 19/117 (16%)
Query: 900 PMGTHTSPLQPLGPPAVAPSRIRTLPLARSSARA----AETKQGLALRPGDPPLLPPRPP 955
P GT + PP ++P R PL+ S A + + + L+ PP P+ P
Sbjct: 21 PRGTLSRSQSVSPPPVLSPPRSPIYPLSDSETSACRYPSHSSSRVLLKDRHPPAPSPQNP 80
Query: 956 QGLEP-TLQPSAPQQA--------------RDPFEDLLQKTKQDVSPSPALAPAPDS 997
Q P T P+ P + RD ++ +Q QDV+ A P S
Sbjct: 81 QDPSPDTSPPTCPFKTASFGYLDRSPSACKRDAQKESVQGAAQDVAGVAACLPLAQS 137
>gi|21264614 suppression of tumorigenicity 5 isoform 2 [Homo
sapiens]
Length = 717
Score = 152 bits (383), Expect = 2e-36
Identities = 107/379 (28%), Positives = 185/379 (48%), Gaps = 43/379 (11%)
Query: 31 PEVQRQFP-------EDYSDQEVLQTLTKFCFPFYVDSLTVSQVG-QNFTFVLTDIDSKQ 82
PEV QFP + +E L+ + +FCFP D L VS+ + F+F+LT D +
Sbjct: 296 PEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSR 355
Query: 83 RFGFCR--LSSGA----KSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNEL----L 132
RFG+CR L SG +C++S L F +F K+L+ +R+ L +
Sbjct: 356 RFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLD-----EVERRRGISAALVYPFM 410
Query: 133 ETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENR----NLTEYFVAVDVNNMLHLY 188
+L + P P PG ++ + + EL ++R + F + V ++ ++
Sbjct: 411 RSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIF 470
Query: 189 ASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIG 248
AS+L ERR++ + KLSTL++C H A+LYP WQH +IPVLP ++D C P P+L+G
Sbjct: 471 ASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVG 530
Query: 249 IHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQS-LPNDVISSLKNRLKKVS------ 301
+ S + K++ + +++ +++N+ ++ DD + LP + ++L+ L++ +
Sbjct: 531 LLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQD 590
Query: 302 ---------TTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMR 352
T V+ F++ G Y L + F EAF S ++R
Sbjct: 591 SDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIR 650
Query: 353 QFLQNATQLQLFKQFIDGR 371
+FL+ + Q+F FI R
Sbjct: 651 RFLEVFMESQMFAGFIQDR 669
>gi|121949817 DENN/MADD domain containing 2C [Homo sapiens]
Length = 871
Score = 150 bits (379), Expect = 6e-36
Identities = 117/414 (28%), Positives = 206/414 (49%), Gaps = 49/414 (11%)
Query: 5 IKQNPETTFEVYVEVAYPRTGGTLSD-PEVQRQFP--------EDYSDQEVLQTLTKFCF 55
I+ + FE++V V+ + +S P+V +QFP + +E L+ + KFCF
Sbjct: 426 IELQEQQLFELFVVVSLQKKPSGISYIPQVIQQFPGKDDHGYKQSKDMEERLKVIPKFCF 485
Query: 56 PFYVDSLTVSQV-GQNFTFVLTDIDSKQRFGFCR----LSSGAK--SCFCILSYLPWFEV 108
P D + S++ + F+FVLT D + FG+C+ + G + +C++S L F +
Sbjct: 486 PDSKDWMPTSELKSETFSFVLTGEDGSRWFGYCKKLLPVGKGKRLPEVYCMVSRLGCFNL 545
Query: 109 FYKLLNILADYTTKRQENQ---WNELLETLHKLPIPDPGVSVHLSVHSYF------TVPD 159
F K+L D KR+E + ++ + P P PG ++ +V SY ++
Sbjct: 546 FSKIL----DEVEKRREMSPALVYPFMRSVMEAPFPAPGRTI--TVKSYLPGAGDESIEL 599
Query: 160 TRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLY 219
R L S E+ + F + V +++ + AS+L ERR++ + + LSTL+ C H A LY
Sbjct: 600 CRPLDSRLEHVDFKCLFKCLSVCHLIRVCASLLLERRVIFVANSLSTLSKCGHAVVATLY 659
Query: 220 PMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNT-LETP 278
P WQH YIPVLP ++D C+P P+LIGI + +++++ +++V+I+++ + L+
Sbjct: 660 PFTWQHTYIPVLPASMIDIVCSPTPFLIGILSCSLPQLQDLPIEEVLIVDLCADKFLQEV 719
Query: 279 FDDLQSLP--------------NDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYR 324
D+ + LP N++++ +N + V T V+ AF++ G Y
Sbjct: 720 SDEDEILPPKLQAALMQILEERNEILTQEQNFSQDV--TLNSLVSEAFVRFFVELVGHYS 777
Query: 325 NALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQLQLFKQFIDGRLDLLNSG 378
+ + F E F + S ++R FL + Q+F FI R +L SG
Sbjct: 778 LNMTVTERGERVFQREPFRKSHTSRSVRHFLDLFMETQMFAGFIQDR-ELRKSG 830
>gi|21361991 DENN/MADD domain containing 2D [Homo sapiens]
Length = 471
Score = 147 bits (371), Expect = 5e-35
Identities = 107/393 (27%), Positives = 193/393 (49%), Gaps = 44/393 (11%)
Query: 30 DPEVQRQFP--------EDYSDQEVLQTLTKFCFPFYVDSLTVSQVG-QNFTFVLTDIDS 80
+P + QFP + ++ +L+ + FCFP + ++++ + F+FVLT++D
Sbjct: 72 EPIITYQFPKRENLLRGQQEEEERLLKAIPLFCFPDGNEWASLTEYPRETFSFVLTNVDG 131
Query: 81 KQRFGFCR--LSSGA----KSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNEL--- 131
++ G+CR L +G +CI+S + F +F K+L D KR + +
Sbjct: 132 SRKIGYCRRLLPAGPGPRLPKVYCIISCIGCFGLFSKIL----DEVEKRHQISMAVIYPF 187
Query: 132 LETLHKLPIPDPGVSVHLSVHSYFTVPD--------TRELPSIPENRNLTEYFVAVDVNN 183
++ L + P PG +V L +PD TR L S E+ + + +
Sbjct: 188 MQGLREAAFPAPGKTVTLKSF----IPDSGTEFISLTRPLDSHLEHVDFSSLLHCLSFEQ 243
Query: 184 MLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPM 243
+L ++AS + ER+I+ + LSTL+ CIH +AA+LYP W H YIPV+P LL C P
Sbjct: 244 ILQIFASAVLERKIIFLAEGLSTLSQCIHAAAALLYPFSWAHTYIPVVPESLLATVCCPT 303
Query: 244 PYLIGIHLSLMEKVRNMALDDVVILNVDTNT-LETPFDDLQSLP----NDVISSLKNRLK 298
P+++G+ + ++V + +++V+++N+ T L + D+ LP +D++ SL +
Sbjct: 304 PFMVGVQMRFQQEVMDSPMEEVLLVNLCEGTFLMSVGDEKDILPPKLQDDILDSLGQGIN 363
Query: 299 KVSTT--TGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQ 356
++ T + V+ F++ G Y + +K E F E +F S R+F++
Sbjct: 364 ELKTAEQINEHVSGPFVQFFVKIVGHYASYIKREANGQGHFQERSFCKALTSKTNRRFVK 423
Query: 357 NATQLQLFKQFIDGRLDLLNSGEGFSDVFEEEI 389
+ QLF FI N G+ F+++I
Sbjct: 424 KFVKTQLFSLFIQEAEKSKNPPAGY---FQQKI 453
>gi|44889475 RAB6 interacting protein 1 [Homo sapiens]
Length = 1287
Score = 88.2 bits (217), Expect = 4e-17
Identities = 61/224 (27%), Positives = 106/224 (47%), Gaps = 15/224 (6%)
Query: 76 TDIDSKQRFGFCRLSSGA---KSCFCILSYLPWFEVFYKLLNILADYTTKRQENQW---N 129
T + QRF +S C C+++ + + + +L L T Q +
Sbjct: 183 TPVTKLQRFNSYDISRDTLYVSKCICLITPMSFMKACRSVLEQLHQAVTSPQPPPLPLES 242
Query: 130 ELLETLHKLPIPDPGVSVHLS-VHSYFTV--PDTRELPSIPENRNLTEYFVAVDVNNMLH 186
+ L+++P+P PG S+ S V+ P T ELP + + E F + V N+
Sbjct: 243 YIYNVLYEVPLPPPGRSLKFSGVYGPIICQRPSTNELPLF--DFPVKEVFELLGVENVFQ 300
Query: 187 LYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYL 246
L+ L E +IL+ L A+++P WQHVY+P+LP LL + AP+PYL
Sbjct: 301 LFTCALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLLHFLDAPVPYL 360
Query: 247 IGIHLSLMEKVRNMALD---DVVILNVDTNTLETPFDDLQSLPN 287
+G+H + ++ + L ++ +++D + +E P +DL PN
Sbjct: 361 MGLHSNGLDDRSKLELPQEANLCFVDIDNHFIELP-EDLPQFPN 403
>gi|122891862 DENN/MADD domain containing 5B [Homo sapiens]
Length = 1274
Score = 79.3 bits (194), Expect = 2e-14
Identities = 62/241 (25%), Positives = 109/241 (45%), Gaps = 15/241 (6%)
Query: 59 VDSLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILAD 118
+DSL S + + T L + + R + C+++ LP+ + K L L
Sbjct: 155 MDSLA-SSLDEGDTTSLLKLQRYNSYDISRDTLYVSKSICLITPLPFMQACKKFLIQLYK 213
Query: 119 YTTKRQENQW---NELLETLHKLPIPDPGVSVHLSVHSYFTV----PDTRELPSIPENRN 171
T +Q + + L+++P+P PG S+ Y V P ELP +
Sbjct: 214 AVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKF-YGVYEPVICQRPGPSELPL--SDYP 270
Query: 172 LTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVL 231
L E F + + N++ ++ +L E +IL+ L G +L+P WQHVY+P+L
Sbjct: 271 LREAFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPIL 330
Query: 232 PPHLLDYCCAPMPYLIGIHLSLMEKVRNMALD---DVVILNVDTNTLETPFDDLQSLPND 288
P LL + AP+PYL+G+ + L ++ +++D + +E P ++ PN
Sbjct: 331 PASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELP-EEFPQFPNK 389
Query: 289 V 289
V
Sbjct: 390 V 390
>gi|94818781 DENN/MADD domain containing 4C [Homo sapiens]
Length = 1673
Score = 79.3 bits (194), Expect = 2e-14
Identities = 79/328 (24%), Positives = 127/328 (38%), Gaps = 51/328 (15%)
Query: 90 SSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNE--LLETLHKLPIPDPG--- 144
S C C+LS+ P+FE F K L + + E + + +P P P
Sbjct: 70 SINTNKCICLLSHWPFFEAFRKFLMFIYKLSVSGPHPLPIEKHISHFMQNIPFPSPQRPR 129
Query: 145 VSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKL 204
+ V LSVH + P N + + + N L +L E +IL+ +
Sbjct: 130 ILVQLSVHDALILSQPVSTPLPLSGANFSTLLMNLGPENCATLLLFVLLESKILLHSLRP 189
Query: 205 STLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDD 264
+ LT AM++P WQ YIP+ P L AP+P+++G+ + + D
Sbjct: 190 AVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFD--LHDPPQD 247
Query: 265 VVILNVDTNTL----ETPFDDLQSLPNDVISSLKNRLKK-------VSTTTGDG------ 307
VV +++DTN L E + + LP +L + LKK V T +G
Sbjct: 248 VVCIDLDTNMLYVSDEKKNMNWKQLPKKPCKNLLSTLKKLYPQLSSVHQKTQEGSAIDMT 307
Query: 308 ------------------VARAFLKAQAAFFGSYRNALKIEPEEPIT--------FCEEA 341
+ AFL+ A+ YR L+ E P F +
Sbjct: 308 PIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTYLRPITEAPSNKATAADSLFDRQG 367
Query: 342 FVSHYRSGAMRQFLQNATQLQLFKQFID 369
F+ R A +F ++ Q+F +FI+
Sbjct: 368 FLKS-RDRAYAKFYTLLSKTQIFIRFIE 394
>gi|221307568 DENN/MADD domain containing 4A isoform 1 [Homo
sapiens]
Length = 1906
Score = 78.2 bits (191), Expect = 4e-14
Identities = 89/377 (23%), Positives = 146/377 (38%), Gaps = 59/377 (15%)
Query: 42 SDQEVLQTLTKFCFPFYVDSLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILS 101
S ++V +F P+ ++LT Q LT D K + C C+LS
Sbjct: 264 SAEKVYGAAIQFYEPYSEENLTEKQ---RLLLGLTSADGKSDSS---KTIHTNKCICLLS 317
Query: 102 YLPWFEVFYKLLNILADYTTKRQENQWNE--LLETLHKLPIPDPG---VSVHLSVHSYFT 156
+ P+F+ F K L L Y+ E + +HK+P P P + V LS H
Sbjct: 318 HWPFFDAFRKFLTFLYRYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLI 377
Query: 157 VPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAA 216
+ P + + N + L + E +ILI + S LT+ +
Sbjct: 378 LSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVS 437
Query: 217 MLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLE 276
M++P +W Y+P+ P L D AP P+++GI + DV ++VDTNT+
Sbjct: 438 MIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYD--PPPDVSCVDVDTNTIS 495
Query: 277 ------------TPFDDLQSLPNDVISSLKNRLKKVSTTTGDG----------------- 307
P ++L N +++L +L K+ D
Sbjct: 496 QIGDKKNVAWKILPKKPCKNLMN-TLNNLHQQLAKLQQRPRDDGLMDLAINDYDFNSGKR 554
Query: 308 -------VARAFLKAQAAFFGSYRNALK---IEPEEPIT-----FCEEAFVSHYRSGAMR 352
+ AFL A+ YR+ L+ P E T F +AF+ R + +
Sbjct: 555 LHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLFALQAFL-RSRDRSHQ 613
Query: 353 QFLQNATQLQLFKQFID 369
+F T+ Q+F +FI+
Sbjct: 614 KFYNMMTKTQMFIRFIE 630
>gi|221307566 DENN/MADD domain containing 4A isoform 2 [Homo
sapiens]
Length = 1863
Score = 78.2 bits (191), Expect = 4e-14
Identities = 89/377 (23%), Positives = 146/377 (38%), Gaps = 59/377 (15%)
Query: 42 SDQEVLQTLTKFCFPFYVDSLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILS 101
S ++V +F P+ ++LT Q LT D K + C C+LS
Sbjct: 264 SAEKVYGAAIQFYEPYSEENLTEKQ---RLLLGLTSADGKSDSS---KTIHTNKCICLLS 317
Query: 102 YLPWFEVFYKLLNILADYTTKRQENQWNE--LLETLHKLPIPDPG---VSVHLSVHSYFT 156
+ P+F+ F K L L Y+ E + +HK+P P P + V LS H
Sbjct: 318 HWPFFDAFRKFLTFLYRYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLI 377
Query: 157 VPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAA 216
+ P + + N + L + E +ILI + S LT+ +
Sbjct: 378 LSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVS 437
Query: 217 MLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLE 276
M++P +W Y+P+ P L D AP P+++GI + DV ++VDTNT+
Sbjct: 438 MIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYD--PPPDVSCVDVDTNTIS 495
Query: 277 ------------TPFDDLQSLPNDVISSLKNRLKKVSTTTGDG----------------- 307
P ++L N +++L +L K+ D
Sbjct: 496 QIGDKKNVAWKILPKKPCKNLMN-TLNNLHQQLAKLQQRPRDDGLMDLAINDYDFNSGKR 554
Query: 308 -------VARAFLKAQAAFFGSYRNALK---IEPEEPIT-----FCEEAFVSHYRSGAMR 352
+ AFL A+ YR+ L+ P E T F +AF+ R + +
Sbjct: 555 LHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLFALQAFL-RSRDRSHQ 613
Query: 353 QFLQNATQLQLFKQFID 369
+F T+ Q+F +FI+
Sbjct: 614 KFYNMMTKTQMFIRFIE 630
>gi|50345870 DENN/MADD domain containing 3 [Homo sapiens]
Length = 1198
Score = 76.6 bits (187), Expect = 1e-13
Identities = 72/286 (25%), Positives = 124/286 (43%), Gaps = 32/286 (11%)
Query: 47 LQTLTKFCFPFYVDSLTVSQVGQNFTFVLTDIDSKQRFG------------FC----RLS 90
L TL + CFP V T + VLTD+ + +G +C +
Sbjct: 39 LLTLPQLCFPGGVCVATEPKEDCVHFLVLTDVCGNRTYGVVAQYYRPLHDEYCFYNGKTH 98
Query: 91 SGAKSCF-----CILSYLPWF----EVFYKLLNILADYTTKRQENQWNELLETLHKLPIP 141
CF C++S P++ + LL +L ++ + L +P P
Sbjct: 99 RECPGCFVPFAVCVVSRFPYYNSLKDCLSCLLALLKPCKDFEVDSHIKDFAAKLSLIPSP 158
Query: 142 DPGVSVHL--SVHSYFTVPDTRELPSIPE-NRNLTEYFVAVDVNNMLHLYASMLYERRIL 198
PG +HL ++ S V R P P + +L + +L + +L E+RI+
Sbjct: 159 PPG-PLHLVFNMKSLQIVLPARADPESPILDLDLHLPLLCFRPEKVLQILTCILTEQRIV 217
Query: 199 IICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVR 258
S + LT A LYP+ WQH ++P+L +LD+ AP +L+G HL E+V
Sbjct: 218 FFSSDWALLTLVTECFMAYLYPLQWQHPFVPILSDQMLDFVMAPTSFLMGCHLDHFEEVS 277
Query: 259 NMALDDVVILNVD--TNTLETPFDDLQSLPNDVISSLKNRLKKVST 302
A D +V++N+D + T DD +P+ + + + +++V +
Sbjct: 278 KEA-DGLVLINIDHGSITYSKSTDDNVDIPDVPLLAAQTFIQRVQS 322
>gi|29788755 SET binding factor 2 [Homo sapiens]
Length = 1849
Score = 74.3 bits (181), Expect = 5e-13
Identities = 91/418 (21%), Positives = 155/418 (37%), Gaps = 68/418 (16%)
Query: 33 VQRQFPEDYSDQEVLQTLTKFCFPFYVDSLTVSQVGQNFTFVLTDIDSKQRFGFC----- 87
+QR +D+ D Q + FC P + F VLTDIDS + + C
Sbjct: 28 IQRFPQKDWDDTPFPQGIELFCQPGGWQLSRERKQPTFFVVVLTDIDSDRHYCSCLTFYE 87
Query: 88 -----------RLSSGAK-------------SCFCILSYLPWFEVFYKLLNILADYTTKR 123
+ AK ++S L + E+F L ++
Sbjct: 88 AEINLQGTKKEEIEGEAKVSGLIQPAEVFAPKSLVLVSRLYYPEIFRACLGLIYTVYVDS 147
Query: 124 QENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNL-------TEYF 176
L+ L +P G S L + R+L P + +L F
Sbjct: 148 LNVSLESLIANLCACLVPAAGGSQKL----FSLGAGDRQLIQTPLHDSLPITGTSVALLF 203
Query: 177 VAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLL 236
+ + N+L L+ ++L E ++L + L+ ++++P+ + + YIP+LP LL
Sbjct: 204 QQLGIQNVLSLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLL 263
Query: 237 DYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETP-FDDLQSLPNDVISSLKN 295
+ +P P++IG+H V + DV+I ++D T++ P L SLP ++ ++
Sbjct: 264 EVLSSPTPFIIGVHSVFKTDVHELL--DVIIADLDGGTIKIPECIHLSSLPEPLLHQTQS 321
Query: 296 RLKKV---------------------STTTGDGVARAFLKAQAAFFGSYRNAL---KIEP 331
L + S V FL+ A F YR+ L +I
Sbjct: 322 ALSLILHPDLEVADHAFPPPRTALSHSKMLDKEVRAVFLRLFAQLFQGYRSCLQLIRIHA 381
Query: 332 EEPITFCEEAFVSHYRSGAMRQFLQNATQLQLFKQFIDGRLDLLNSGEGFSDVFEEEI 389
E I F + AF+ R FL F F+ R S + F ++ E+
Sbjct: 382 EPVIHFHKTAFLGQ-RGLVENDFLTKVLSGMAFAGFVSERGPPYRSCDLFDELVAFEV 438
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 70.9 bits (172), Expect = 6e-12
Identities = 135/551 (24%), Positives = 180/551 (32%), Gaps = 86/551 (15%)
Query: 462 TPEEQLPKTAPSPLVEAKDPKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRR--T 519
TP Q P + +P ++A P + PI V P ++ P S +A+ + T
Sbjct: 363 TPPSQAPPSMTTPPMQA--PPSLQTIPPIQVPHSLTSPS----LQAPPSPLALSSLQATT 416
Query: 520 SVPSPEQPQPYRTLRESDSAEGDEAESPEQQVRKSTGPVPAPPDRAASIDLLEDVFSNLD 579
S+ SP + L S SP R ++ P +PP +A + L
Sbjct: 417 SLGSPTLQATHSFLTMSPRQTQASLTSPS---RPASTPPDSPPLQAP-LSLPASPPLQTS 472
Query: 580 MEAALQPLGQAKSLEDLRAPKDLREQPGTFDYQRLDLGGSERSRGVTVALKLTHPYNKLW 639
+ A+ PL ++ L+A L L + E + T P + L
Sbjct: 473 LSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPAS-LT 531
Query: 640 SLGQDDMAIPSKPPAASPEKPSALLGNSLALPRRPQNRDSILNPSDKEEVPTPTLGSITI 699
+ +++ + PP + P L L P P PS P T SI
Sbjct: 532 TPPLENLPSLAPPPLQTASAP--LTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIAT 589
Query: 700 PRPQGRK---TPELGIVPPPPI-PRPAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPG 755
P PQ +P L +P PP+ P A L + LSP P
Sbjct: 590 PPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPS 649
Query: 756 VVPQGPTELLQPLSPGPGAAGTSSDALLALLDPLSTAWSGSTLPSRPATPNVATPFTPQF 815
PQ P L L P + S P S S S P A P++A P
Sbjct: 650 --PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 707
Query: 816 SFPPAGTP-----TPFPQ-------------------PPLNPFVPSMPAAPPTL------ 845
PPA P TP PQ PP++P P PP L
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQ 767
Query: 846 ----PLVSTPAGPFGAPPASLGPAFASGLLLSSAGFCAPHRSQPNLSALSMP--NLFGQM 899
P S P P PP PA A+ P L AL P + GQ
Sbjct: 768 VPPSPPASLPMSPLAKPPPQAPPALAT----------------PPLQALPSPPASFPGQA 811
Query: 900 PMGTHTS-PLQPLG-PPAVAPSRIRTLPLARSSARAAETKQGLALRPGDPPLLPPRPPQG 957
P S P+ PL PP AP + AA Q P P L PR P
Sbjct: 812 PFSPSASLPMSPLATPPPQAPPVL-----------AAPLLQVPPSPPASPTLQAPRRPPT 860
Query: 958 LEPTLQPSAPQ 968
P S P+
Sbjct: 861 PGPDTSVSGPR 871
Score = 64.3 bits (155), Expect = 5e-10
Identities = 142/585 (24%), Positives = 192/585 (32%), Gaps = 107/585 (18%)
Query: 462 TPEEQLPKTAPSP--LVEAKDPKLREDRRPITVHFGQVRP-----PRPHVVKR----PKS 510
TP + P P L + P++ R+ G + P P K P
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321
Query: 511 NIAVEGRRTSVPSPEQPQPYRTLRESDSAEGDEAESPEQQVRKSTGPVPAPPDRAASIDL 570
N A T PSP P S SA P +T P APP
Sbjct: 322 NAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP---ATPPSQAPPSMTTP--- 375
Query: 571 LEDVFSNLDMEAALQPLGQAKSLEDLRAPKDLREQPGTFDYQRLDLGGSERSRGVTVALK 630
+ +LQ + + L +P L+ P L S S L+
Sbjct: 376 ------PMQAPPSLQTIPPIQVPHSLTSPS-LQAPPSPLALSSLQATTSLGSP----TLQ 424
Query: 631 LTHPYNKLWSLG-QDDMAIPSKPPAASPEKPSALLGNSLALPRRPQNRDSI--------- 680
TH + + Q + PS+P + P+ P L L+LP P + S+
Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRPASTPPDSPP--LQAPLSLPASPPLQTSLSPAVSPLSS 482
Query: 681 ---LNP-----SDKEEVPTPTLGSITIP--------RPQGRKTPELGIVPPP----PIPR 720
++P S P L S+ +P P +TP + PP P
Sbjct: 483 PLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA 542
Query: 721 PAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPGVVPQGPTELLQPLSPGPGAAGTSSD 780
P LQ A A L + L+T P P P P P +P A
Sbjct: 543 PPPLQTASAPL--TTPHLETPP------CPAPCPLQAPPSPLTTPPPETPS-SIATPPPQ 593
Query: 781 ALLALLDPLSTAWSGSTLPSRPATPNVATP---FTPQFSFPPA-GTPTPFPQPPLNPFVP 836
A AL P LPS P +P +ATP P + PP P+P PPL+P
Sbjct: 594 APPALASPPLQG-----LPSPPLSP-LATPPPQAPPXLALPPLQAPPSPPASPPLSPLAT 647
Query: 837 SMPAAPPTLP--LVSTPAGPFGAPPASLGPAFASGLLLSSAGFCAPHRSQPNLSALSMPN 894
P AP L L+ P P +PP A F P + P +S + P
Sbjct: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQ-------------APFSPP--ASPPVSPSATPP 692
Query: 895 LFGQMPMGTHTSPLQ-PLGPPAVAPSRIRTLPLARSSARAAETKQGLALRPGD-PPLLPP 952
Q P PLQ P PPA + P++ S+ + LA P PP P
Sbjct: 693 --SQAPPSLAAPPLQVPPSPPA-------SPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743
Query: 953 RPPQGLEPTLQPSAPQQARDPFEDLLQKTKQDVSPSPALAPAPDS 997
PP T P P P + + SP P P +
Sbjct: 744 SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA 788
Score = 62.0 bits (149), Expect = 3e-09
Identities = 96/347 (27%), Positives = 129/347 (37%), Gaps = 48/347 (13%)
Query: 653 PAASPEKPSALLGNSLALPR-RPQNRDSILNPSDKEEVPTPTLGSITIPRPQGRKTPELG 711
P+ + + S G + LPR P R ++ V + + S T P P R+ P G
Sbjct: 172 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231
Query: 712 IVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPGVVPQGPTELLQPLSPG 771
+ RPA + +A S R +P P+G LQ L P
Sbjct: 232 ----GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG----LQALRP- 282
Query: 772 PGAAGTSSDALLALLDPLSTAWSGSTLPS----RPATP--NVATPFTPQFSFPPAGTPTP 825
P DA AL PLS++ + PS RP P N ATP PA P
Sbjct: 283 PQVTPPRKDAAPAL-GPLSSSPLATPSPSGTKARPVPPPDNAATPL-------PATLP-- 332
Query: 826 FPQPPLN---PFVPSMPAAPPTLP-LVSTPAGPFGAPPASL--GPAFASGLLLSSAGFCA 879
P PPL P P P+APP+L L S PA P P S+ P A L +
Sbjct: 333 -PSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQV 391
Query: 880 PHR-SQPNLSALSMPNLFGQMPMGTHTSPLQPLGPPAV-APSRIRTLPLARSSARAAETK 937
PH + P+L A P + T LG P + A T+ ++ A
Sbjct: 392 PHSLTSPSLQAPPSPLALSSLQATT------SLGSPTLQATHSFLTMSPRQTQASLTSPS 445
Query: 938 QGLALRPGDPPL-----LPPRPP--QGLEPTLQPSAPQQARDPFEDL 977
+ + P PPL LP PP L P + P + P + L
Sbjct: 446 RPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL 492
Score = 50.1 bits (118), Expect = 1e-05
Identities = 103/409 (25%), Positives = 129/409 (31%), Gaps = 64/409 (15%)
Query: 463 PEEQLPKTAPSPLVEAKDPKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRRT--- 519
P E LP AP PL A P T H P P ++ P S + T
Sbjct: 534 PLENLPSLAPPPLQTASAPLT-------TPHLETPPCPAPCPLQAPPSPLTTPPPETPSS 586
Query: 520 -SVPSPEQPQPYRT--LRESDSAEGDEAESPEQQVRKSTG--PVPAPPDRAASIDLLEDV 574
+ P P+ P + L+ S +P Q P+ APP AS L
Sbjct: 587 IATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPL---- 642
Query: 575 FSNLDMEAALQPLGQAKSLEDLRAPKDLREQPGTFDYQRLDLGGSERSRGVTVALKLTHP 634
S L + P A L L+AP P V+ T P
Sbjct: 643 -SPLATPSPQAPNALAVHL--LQAPFSPPPSPPV-------QAPFSPPASPPVSPSATPP 692
Query: 635 YNKLWSLGQDDMAIPSKPPAASPEKPSA---------LLGNSLALPRRPQNRDSILNPSD 685
SL + +P PPA+ P PSA L L +P P P
Sbjct: 693 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP----PMS 748
Query: 686 KEEVPTPTLGSITIPRPQGRKTPELGIVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRR 745
P P + P P L + P PP P A L T +
Sbjct: 749 PSATPPPRV-------PPLLAAPPLQVPPSPPASLPMSPLAKPPP--QAPPALATPPLQA 799
Query: 746 AALSPGLLPGVVPQGPTELLQPLSPGPGAAGTSSDALLALLDPLSTAWSGSTLPSRPATP 805
P PG P P+ L P+SP A A L PL PS PA+P
Sbjct: 800 LPSPPASFPGQAPFSPSASL-PMSP---LATPPPQAPPVLAAPLL-----QVPPSPPASP 850
Query: 806 NVATPFTPQFSFPPAGTPTPFPQPPLNPFVPSMPAAPPTLPLVSTPAGP 854
+ P P P G T P L + P PP+ ST +GP
Sbjct: 851 TLQAPRRP----PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 895
Score = 40.0 bits (92), Expect = 0.011
Identities = 98/384 (25%), Positives = 132/384 (34%), Gaps = 63/384 (16%)
Query: 649 PSKPPAASPEKPSAL--LGNSLALPRRP--QNRDSILNPSDKEEVPT--PTLGSITIPRP 702
P P P P+AL LG + A+ R+P + I + E P PT + T R
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRN 89
Query: 703 QGRKTPELGI---VPPPPIPRPAKLQAAGAALGD------------------VSERLQTD 741
+ P G PP P + + G A G V+ T+
Sbjct: 90 PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 149
Query: 742 RDRRAALSPGLLPGVVPQGPTELLQPLSPGPGAAGTSSDALLALLDPLSTAWSGSTLPSR 801
+R+ALS G GPT P +P P A S A + P PS
Sbjct: 150 APKRSALSAGARRDT--SGPT----PGTPSPAMARRSRAAGTEVGLPRPA-------PSA 196
Query: 802 PATPNVATPFTPQFSFPPAGTPTPFPQPPLNPFVPSMPAAPPTLPLVSTPAGPFGAPPAS 861
P P S T P P P P + L S+ A P +P S
Sbjct: 197 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL-SSSATPLSSPARS 255
Query: 862 LGPAFASGLLLSSAGFCAPHRSQPN---LSALSMPNLFG-QMPMGTHTSPLQ--PLGPPA 915
GP+ A G + A H SQP L AL P + + PL PL P+
Sbjct: 256 -GPS-ARGTPRAPA-----HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308
Query: 916 VAPSRIRTLPLARSSARAAETKQGLALRPGDPPL---LPPRPPQ-GLEPTLQPSAPQQAR 971
+ ++ R +P ++A A P PPL LP PP P+LQ A
Sbjct: 309 PSGTKARPVPPPDNAATPLP-----ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPAT 363
Query: 972 DPFEDLLQKTKQDVSPSPALAPAP 995
P + T + P+L P
Sbjct: 364 PPSQAPPSMTTPPMQAPPSLQTIP 387
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 70.9 bits (172), Expect = 6e-12
Identities = 112/368 (30%), Positives = 139/368 (37%), Gaps = 52/368 (14%)
Query: 652 PPAASPEKPSALLG----NSLALPRRPQNRDSILNPSDKEEVPTPTLGSITIPRPQGRKT 707
P ASP + LG SL+ + P +L P+ P L S P
Sbjct: 1495 PSGASPSASALTLGLATAPSLSSSQTP-GHPLLLAPTSSH---VPGLNSTVAPACSPVLV 1550
Query: 708 PELGIVPP-PPIPRPAKLQAAGAA-LGDVSERLQTDRDRRAALSPGLLPGVVPQGPTELL 765
P + P P P PA QA+ A S+ L T AA +L P P L
Sbjct: 1551 PASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAIL-APSPAPPLAPL 1609
Query: 766 QPLSPGPGAAGT--SSDALLALLDPLSTAWSGSTLPSR---PATPNVATPFTPQFSFPPA 820
L+P PGAA SS + ++ P ST G++L S PA V P + Q + PA
Sbjct: 1610 PVLAPSPGAAPVLASSQTPVPVMAPSSTP--GTSLASASPVPAPTPVLAPSSTQ-TMLPA 1666
Query: 821 GTPTPFPQPPLNPFVPSMPAAPPTLPLVS----------TPAGPFGAPPASLGPAFASGL 870
P+P P P + PA PTL S P GPF SL P AS L
Sbjct: 1667 PVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTP--ASSL 1724
Query: 871 LLSSAGFCAPHRSQPNLSALSMPNLFGQMPMG-THTSPLQPLGPPAVAPSRIRTLPLARS 929
+ + A LS P L + PL P P AP+ TL A S
Sbjct: 1725 VPTPA---------QTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASS 1775
Query: 930 SAR--AAETKQGLALRPGDPPLLPPRPPQGLEPTLQPSAPQQARDPFEDLLQKTKQDVSP 987
SA A + Q L L P P L P Q L L P++ Q L+ VS
Sbjct: 1776 SASLLAPASVQTLTLSPAPVPTLGPAAAQTL--ALAPASTQSPASQASSLV------VSA 1827
Query: 988 SPALAPAP 995
S A AP P
Sbjct: 1828 SGA-APLP 1834
Score = 57.0 bits (136), Expect = 9e-08
Identities = 101/391 (25%), Positives = 141/391 (36%), Gaps = 76/391 (19%)
Query: 645 DMAIPSKPPAASPEKPSALLGNSLALPRRPQNRDSILNPSDKEEVPTPTLGSITIPRPQG 704
D P P A +P PS+ G L RP L P +PTPTLG+ P P
Sbjct: 1319 DGLTPVPPLAPAPRPPSS--GLPAVLNPRPT-----LTPG---RLPTPTLGTARAPMPTP 1368
Query: 705 RKTPELGIVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPGVVPQGPTEL 764
L + P P A GAA +S L P LPG P
Sbjct: 1369 TLVRPLLKLVHSPSPE-VSASAPGAAPLTISSPLHV---------PSSLPG-----PASS 1413
Query: 765 LQPLSPGPGAAGTSSDALLALLDPLSTAWSGS---TLP---SRPATPNVATPFTPQFSFP 818
P+ P ++ +S + PLS++ S TLP S P T ++ P T S P
Sbjct: 1414 PMPI---PNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGP 1470
Query: 819 PAGTPTPFPQPPLNPFVPSMP------------------AAPPTLPLVSTPAGPFGAPPA 860
T P P+ P P P A P+L TP P P
Sbjct: 1471 ALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPT 1530
Query: 861 S---------LGPAFASGLLLSSAGFCAPHRSQPN----LSALSMPNLFGQMPMGTHTSP 907
S + PA S +L+ ++ +P S PN ++L P + T +P
Sbjct: 1531 SSHVPGLNSTVAPA-CSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAP 1589
Query: 908 LQPLGPPAVAPS---RIRTLPLARSSARAAETKQGLALRPGDPPLLPPRPPQGLEPTLQP 964
+ +APS + LP+ S AA LA P++ P G +L
Sbjct: 1590 MAAPQTAILAPSPAPPLAPLPVLAPSPGAAPV---LASSQTPVPVMAPSSTPG--TSLAS 1644
Query: 965 SAPQQARDPFEDLLQKTKQDVSPSPALAPAP 995
++P A P L + Q + P+P +P P
Sbjct: 1645 ASPVPAPTPV--LAPSSTQTMLPAPVPSPLP 1673
Score = 56.2 bits (134), Expect = 1e-07
Identities = 135/575 (23%), Positives = 190/575 (33%), Gaps = 125/575 (21%)
Query: 461 PTPEEQLPKTAPSP--LVEAKDPKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRR 518
PTP L T P+P L A P +P+TV G PP S
Sbjct: 1100 PTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPP---AAATTTSTTTATATT 1156
Query: 519 TSVPSPEQPQPYRTLRESDSAEGDEAESPEQQVRKSTGPVPAPPDRAASIDLLEDVFSNL 578
T+VP+P P P R + SP+ Q R +G V +
Sbjct: 1157 TAVPAPT-PAPQRLIL-----------SPDMQARLPSGEVVS------------------ 1186
Query: 579 DMEAALQPLGQAKSLEDLRAPKDLREQPGTFDYQ--RLDLGGSE-RSRGVTVALKLTHPY 635
+GQ SL +P TF Q +L L G++ R V L
Sbjct: 1187 --------IGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNV 1238
Query: 636 NKLWSLGQDDMAIPSKPPAASPEKPSALLGNSLALPRRPQNRDSILNPSDKEEVPTPTLG 695
L S G I +P+ + P S+L S P PT
Sbjct: 1239 VHLVSAGGQHHLI---------SQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGL 1289
Query: 696 SITIPRPQGRKTPELGIVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPG 755
S+ + Q VPP + + G++
Sbjct: 1290 SLPLAANQ---------VPPTMVN-----------------------------NTGVVKI 1311
Query: 756 VVPQGPTELLQPLSPGPGAAGTSSDALLALLDPLSTAWSG-------STLPSRPATPNVA 808
VV Q P + L P+ P A S L A+L+P T G T + TP +
Sbjct: 1312 VVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLV 1371
Query: 809 TPF-------TPQFSFPPAGTPTPFPQPPLNPFVPSMPAAPPTLPLVSTPAGPFGAPPAS 861
P +P+ S G PL+ VPS P + P+ + P +P +S
Sbjct: 1372 RPLLKLVHSPSPEVSASAPGAAPLTISSPLH--VPSSLPGPASSPMPIPNSSPLASPVSS 1429
Query: 862 -LGPAFASGLLLSSAGFCAPHRSQPNLSALSMP---NLFGQMPMGTHTSPLQPL-----G 912
+ +S L +S S P +S P + G + + T PL P+ G
Sbjct: 1430 TVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPG 1489
Query: 913 PPAVAPSRIRTLPLARSSARAAETKQGLALRPGDPPLLPPRPPQ--GLEPTLQPSAPQQA 970
PP++APS A + A + PG P LL P GL T+ P A
Sbjct: 1490 PPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAP-ACSPV 1548
Query: 971 RDPFEDLLQKTKQDVSPSPA----LAPAPDSVEQL 1001
P L +P+PA LAPA + + L
Sbjct: 1549 LVPASALASPFPSAPNPAPAQASLLAPASSASQAL 1583
Score = 47.8 bits (112), Expect = 5e-05
Identities = 133/578 (23%), Positives = 206/578 (35%), Gaps = 75/578 (12%)
Query: 446 KNRLKQKDIAENGCAPTPEEQLPKTAPSPLVEAKDPKLREDRRPITVHFGQVRPPRPHVV 505
++RL ++ + E AP P + PK + P +++ R + V R P V
Sbjct: 966 RHRLSRRVLLEVATAPDPPPR-PKPVKMKVNRMLQPVPKQEGRTVVV-VNNPRAPLGPVP 1023
Query: 506 KRPKSNIAVEGRRTSVPSPEQPQPYRTLRESDSAEGDEAESPEQQVRKSTGPVPAPPDRA 565
RP + + T P P+ L S A P + GPV PP +
Sbjct: 1024 VRPPPGPELSAQPTPGPVPQ------VLPASLMVSASPAGPPLIPASRPPGPVLLPPLQP 1077
Query: 566 ASIDLLEDVFSNLD-MEAALQPLGQAKSLEDLRAPKDLREQPGTFDYQRLDLGGSERSRG 624
S L + + S L + +P SL+ P +R P G S +
Sbjct: 1078 NSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPT-PPAPVRLSPAP------PPGSSSLLKP 1130
Query: 625 VTVALKLTHP-----YNKLWSLGQDDMAIPSKPPAA-----SPEKPSAL-------LGNS 667
+TV T P + A+P+ PA SP+ + L +G
Sbjct: 1131 LTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQL 1190
Query: 668 LALPRRPQNRDSILNPSDKEEVPTPTLGS-ITIPRPQGRKTPELGIVPPPPIPRPA-KLQ 725
+L +RP + N + + G+ +T+ Q R +L + P P+ R L
Sbjct: 1191 ASLAQRP-----VANAGGSKPLTFQIQGNKLTLTGAQVR---QLAVGQPRPLQRNVVHLV 1242
Query: 726 AAGAALGDVSERLQTDRDRRAALSPGLLPGVVPQGPTELLQPLSPGPGAAGTSSDALLAL 785
+AG +S+ + A +PG PT P+S P + +++ A L
Sbjct: 1243 SAGGQHHLISQPAHVALIQAVAPTPG---------PT----PVSVLPSSTPSTTPAPTGL 1289
Query: 786 LDPLSTAWSGSTLPSRPATPNVATPFTPQFSFPPAGTPTPFPQPPLNPFVPSMPAAPPTL 845
PL+ T+ + + P+ P P P+PP + +P++ PTL
Sbjct: 1290 SLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPP-SSGLPAVLNPRPTL 1348
Query: 846 PLVSTPAGPFGAPPASL-GPAFASGLLLSSAGFCAPHRSQPNLSALSMPNLFGQMPMGTH 904
P G A + P LL H P +SA S P G P+ T
Sbjct: 1349 TPGRLPTPTLGTARAPMPTPTLVRPLLK------LVHSPSPEVSA-SAP---GAAPL-TI 1397
Query: 905 TSPL---QPLGPPAVAPSRI-RTLPLARSSARAAETKQGLALRPGDPPLLPPRPPQGLEP 960
+SPL L PA +P I + PLA + +L P LP P
Sbjct: 1398 SSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLP--APASAPL 1455
Query: 961 TLQPSAPQQARDPFEDLLQKTKQDVSPSPALAPAPDSV 998
T+ SAP LL ++P AP P S+
Sbjct: 1456 TIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSL 1493
Score = 44.3 bits (103), Expect = 6e-04
Identities = 84/373 (22%), Positives = 118/373 (31%), Gaps = 98/373 (26%)
Query: 580 MEAALQPLGQAKSLEDLRAPKDLREQPGTFDYQRLDLGGSERSRGVTVALKLTHPYNKLW 639
+EAA + L QAK E R P++ E PG D GG TH +K
Sbjct: 2339 VEAARKDLDQAKE-EVFRLPQEEEEGPGAGDESSCGTGGG------------THRRSK-- 2383
Query: 640 SLGQDDMAIPSKPPAASPEKPSALLGNSLALPR---RPQNRDSILNPSDKEEVPTPTLGS 696
A +PE+P + L R + N +++ TP S
Sbjct: 2384 -------------KAKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPRCS 2430
Query: 697 ITIPRPQGRKTPELGIVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPGV 756
P + P P P PRP A P +P +
Sbjct: 2431 -----PARERVPR-----PAPRPRPTPASA-----------------------PAAIPAL 2457
Query: 757 VPQGPTELLQPLS-PGPGAAGTSSDALLALLDPLSTAWSGSTLPSRPATPNVATPFTPQF 815
VP P P+S P P T LPS P + +P
Sbjct: 2458 VPV-PVSAPVPISAPNP-----------------ITILPVHILPSPPPPSQIPPCSSPAC 2499
Query: 816 SFPPAGTPTPFPQPPLNPFVPSMPAAPPTLPLVSTPAGPFGAPPASLGPAFASGLLLSSA 875
+ PPA TP P PP P++P L+ P+ P A +L L A
Sbjct: 2500 TPPPACTPPPAHTPPPAQTCLVTPSSP---LLLGPPSVPISASVTNLPLG-----LRPEA 2551
Query: 876 GFCAPHRSQPNLSALSMPNLFGQMPMGTHTSPLQPLGPPAVAPSRIRTLPLARSSARAAE 935
CA + P L+ + TS L + P + P + LP++ +
Sbjct: 2552 ELCAQALASPESLELA-------SVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTP 2604
Query: 936 TKQGLALRPGDPP 948
+ L L G P
Sbjct: 2605 SAPSLTLEAGSIP 2617
Score = 39.3 bits (90), Expect = 0.019
Identities = 52/200 (26%), Positives = 66/200 (33%), Gaps = 13/200 (6%)
Query: 649 PSKPPAASPEKPSALLGNSLALPRRPQNRDSILNPSDKEEVPTPTLGSITIPRPQGRKTP 708
P+ P PS L P+ P ++ VPTP P P T
Sbjct: 1685 PALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQ 1744
Query: 709 ELGIVPPPPI-------PRPAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPGVVPQGP 761
L + P PP+ P PA A S L + LSP +P + P
Sbjct: 1745 TLSLAPAPPLAPASPVGPAPAHTLTLAPASSSAS-LLAPASVQTLTLSPAPVPTLGPAAA 1803
Query: 762 TEL-LQPLSPGPGAAGTSSDALLALLDPLSTAWSGSTLPSRPATPNVAT----PFTPQFS 816
L L P S A+ SS + A S LP P+ T P +P +
Sbjct: 1804 QTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPST 1863
Query: 817 FPPAGTPTPFPQPPLNPFVP 836
G P P QPP P P
Sbjct: 1864 ATSFGGPRPRRQPPPPPRSP 1883
Score = 36.2 bits (82), Expect = 0.16
Identities = 75/327 (22%), Positives = 118/327 (36%), Gaps = 35/327 (10%)
Query: 497 VRPPRPHVVKRPKSNIAVEGRRTSVPSPEQPQPYRTLRESDSAEGDEAESPEQQVRKSTG 556
V P P ++ P ++ + T++P +P+ + S E E S S
Sbjct: 2521 VTPSSPLLLGPP--SVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLS 2578
Query: 557 PVPAPPDRAASIDLLEDVFSNLDM---------EAALQPLGQAKSLEDLRAPKDLREQPG 607
VP ++++L NL + EA P GQ + D L P
Sbjct: 2579 LVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLP- 2637
Query: 608 TFDYQRLDLGGSERSRGVTVALKLTHPYNKLWSLGQD---DMAIPSKPPAASPEKPSALL 664
+ + L L SE S G+ + L D + +K P +SPEKP L+
Sbjct: 2638 --EGEELPLCVSE-SNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELV 2694
Query: 665 GNSLALPRRPQNRDSILNPSDKEEVPTPTLGSITIPRPQGRKTPELGIVPPPPIPRPAKL 724
+A P + S +P P + +G+ T G P P + R KL
Sbjct: 2695 TAEVAAPSTSSSATS--SPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLR--KL 2750
Query: 725 QAAGAALGDVSERLQTDRDRRAALSPGLLPGVVPQGPTELLQPLSPGPGAAGTSSDALLA 784
+ + E ++ R +R A S L+PGV S PG+ S +
Sbjct: 2751 PGRLVTVVEEKELVRRRRQQRGAAST-LVPGV---------SETSASPGSPSVRSMSGPE 2800
Query: 785 LLDPLS---TAWSGSTLPSRPATPNVA 808
P+ A S+LP+ P P +A
Sbjct: 2801 SSPPIGGPCEAAPSSSLPTPPQQPFIA 2827
>gi|239735519 SET binding factor 1 [Homo sapiens]
Length = 1893
Score = 70.1 bits (170), Expect = 1e-11
Identities = 58/233 (24%), Positives = 105/233 (45%), Gaps = 29/233 (12%)
Query: 165 SIPENR-NLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYW 223
S+P +R ++ F + + N+L L+ + L E ++L + L G A+L+P+ +
Sbjct: 203 SLPVSRCSVALLFRQLGITNVLSLFCAALTEHKVLFLSRSYQRLADACRGLLALLFPLRY 262
Query: 224 QHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPF---- 279
Y+P+LP LL+ P P++IG++ + + + + DV++ ++D T+ P
Sbjct: 263 SFTYVPILPAQLLEVLSTPTPFIIGVNAAFQAETQELL--DVIVADLDGGTVTIPECVHI 320
Query: 280 ----DDLQSLPNDVISSLKN--------RLKKVSTTTG-----DGVARA-FLKAQAAFFG 321
+ LQS + V+S + + +T+T D RA FL+ A
Sbjct: 321 PPLPEPLQSQTHSVLSMVLDPELELADLAFPPPTTSTSSLKMQDKELRAVFLRLFAQLLQ 380
Query: 322 SYR---NALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQLQLFKQFIDGR 371
YR + ++I PE I F + AF+ R FL + F F+ R
Sbjct: 381 GYRWCLHVVRIHPEPVIRFHKAAFLGQ-RGLVEDDFLMKVLEGMAFAGFVSER 432
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 68.9 bits (167), Expect = 2e-11
Identities = 122/485 (25%), Positives = 176/485 (36%), Gaps = 68/485 (14%)
Query: 508 PKSNIAVEGRRTSVP--------SPEQPQPYRTLRESDSAEGDEAESPEQQVRKSTGPVP 559
PK++ EG T++P P P P T + E P+ S P
Sbjct: 685 PKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVL-APEIPKSVPSPSLPPAG 743
Query: 560 APPDRAASIDLLEDVFSNLDMEAALQPLGQAKS---LEDLRAPKDLREQPGTFDYQRLDL 616
PP +D + +AL P+ + ED A + GT Y L
Sbjct: 744 TPPG-TKKVD-------GISHTSALAPVASSPKECPTEDSGASATASSK-GTLTY----L 790
Query: 617 GGSERSRGVTVALKLTHPYNKLWSLGQDDMAIPSKPPAASPEKPSALLGNSLALPRRPQN 676
S GV+V+ + P K S G D I + SP + S L NSL+ +
Sbjct: 791 ADSPSPLGVSVSPQTKRPPTKKGSAGPDT-PIGNLSSPVSPVEASFLPENSLSFQGSKDS 849
Query: 677 RDSILNPSDKEEVPTPTLGSITIPRPQG-----RKTPELGIVPPPPIPRPAKLQAAGAAL 731
+ +P+ PT ++T P+G ++TP +V +P P + A A
Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVV---NLPFPKEGPATPAPK 906
Query: 732 GDVSERLQTDRDRRAALSPGLLPGVVPQGPTELLQPLSPGPGAAGTSSDALLALLDPLST 791
+ + + ++A +P P+G P SP P A T A P
Sbjct: 907 QAPALSMTSSSPKKARATP------APKG-----IPASPSPKGAPTPP----AATPPSPK 951
Query: 792 AWSGSTLPSRPATPNVATPFTPQ---FSFPPAGTPTP----FPQPPLNPFVPSMPAAPPT 844
+ P TP ATP +P+ + P G PTP P P P PS P PT
Sbjct: 952 GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPS-PKGAPT 1010
Query: 845 LPLVSTPAGPFGAPPASLGPAFASGLLLSSAGFCAPHRSQPNLSALSMPNLFGQMPMGTH 904
P V TP P G+P A+ P A S+ P + + +A +P P T
Sbjct: 1011 PPAV-TPPSPKGSPAATPFPKGA-----STPPAATPPSPKGSPAATPLPKGAPTTPAATL 1064
Query: 905 TSPLQPLGPPAV--APSRIRTLPLARSSARAAETKQGLALRPGDPPLLPPRPPQGLEPTL 962
SP P++ AP+ P + A + +G P P PP P GL
Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG---APMPPAATPPSPKGGLATPP 1121
Query: 963 QPSAP 967
AP
Sbjct: 1122 HKGAP 1126
Score = 68.2 bits (165), Expect = 4e-11
Identities = 97/372 (26%), Positives = 125/372 (33%), Gaps = 65/372 (17%)
Query: 649 PSKPPAASPEKPSALLGNSLALPRRPQNRDSILN---PSDKEEVPTPTLG---SITIPRP 702
PS A +P + L + LP + S++N P + P P S+T P
Sbjct: 859 PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP 918
Query: 703 Q-GRKTPELGIVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPGVVPQGP 761
+ R TP +P P P+ A A A T + A P P GP
Sbjct: 919 KKARATPAPKGIPASPSPKGAPTPPA-ATPPSPKGGPATPSPKWAPTPPAATPPSPKGGP 977
Query: 762 TELLQPLSPGPGAAGTSSD-ALLALLDPLSTAWSGSTLPSRPATPNVATPFTPQFSFPPA 820
+P P AA S A P + P P ATPF S PPA
Sbjct: 978 ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037
Query: 821 GTP---------TPFPQ------------PPLNPFVPSMPAAPPTLPLVSTPAGPFGA-- 857
TP TP P+ P P PS+ AP P +TP P G
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP--TPPAATPPSPKGGPA 1095
Query: 858 ---------PPASLGPAFASGLLLSSAGFCAPHRSQPNLSALSMPNLFGQM----PMGTH 904
PPA+ P+ GL PH+ P A + P+ G + P G
Sbjct: 1096 TPSPKGAPMPPAATPPSPKGGLA------TPPHKGAPTTPAATPPSPKGGLATPPPKGAP 1149
Query: 905 TSPL----QPLG-----PPAVAPSRIRTLPLARSSARAAETKQGLALRPGDPPLLPPRPP 955
T+P P G PP AP+ P + A + +G P P PP P
Sbjct: 1150 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKG---APTTPAATPPSPK 1206
Query: 956 QGLEPTLQPSAP 967
GL AP
Sbjct: 1207 GGLATPSPKGAP 1218
Score = 60.8 bits (146), Expect = 6e-09
Identities = 104/440 (23%), Positives = 138/440 (31%), Gaps = 103/440 (23%)
Query: 648 IPSKPPAASPEKPSALLGNSLALPRRPQNRDSILNPSDKEEVPTPTL------GSITIPR 701
+ + PP +P P+A P + + P K TP G + P
Sbjct: 1140 LATPPPKGAPTTPAAT---------PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS 1190
Query: 702 PQGRKTPELGIVPPP------PIPRPAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPG 755
P+G T P P P P+ A A A L T + A +P P
Sbjct: 1191 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPA-ATPPSPKGGLATPSPKGAPTTPAATPP 1249
Query: 756 VVPQGPTELLQPLSPGPGAAGTSS------------DALLALLDPLSTAWSGSTLPSRPA 803
GP +P P AA S A++ P S +T P + A
Sbjct: 1250 SPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA 1309
Query: 804 -TPNVATPFTPQFSF---PPAGTPTPFPQPPLNP--------FVPSMPAAPPTLPLVSTP 851
TP ATP +P+ S PP G PTP P +P PS P T P
Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGP 1369
Query: 852 AGPFGAPPASLGPAFASGLLLSSAGFCAPHRSQPNLSALSMPNLFGQMPMGTHTSPLQP- 910
P P GPA +P R S P +P+ +P P
Sbjct: 1370 TPPAATPSHKGGPAMTPP---------SPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPV 1420
Query: 911 ------------LGPPAVAPSRIRTLPL--ARSSARAAETKQGLALRPGDPPLLPPRPPQ 956
L PPAV P ++ P A A + +G P P P PP
Sbjct: 1421 TREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPA 1480
Query: 957 GLE-------------------PTLQ----------PSAPQQARDPFED----LLQKTKQ 983
+ PTL P+ P RDP L +KT
Sbjct: 1481 PKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPA 1540
Query: 984 DVSPSPALAPAPDSVEQLRK 1003
++P AL P +V +K
Sbjct: 1541 TLAPKEALIPPAMTVPSPKK 1560
Score = 59.7 bits (143), Expect = 1e-08
Identities = 106/436 (24%), Positives = 151/436 (34%), Gaps = 110/436 (25%)
Query: 647 AIPSKPPAASPEKPSALLGNSLALPRRPQNRDSILNPSDKEEVPTPTLGSITIPRPQGRK 706
AIPS P P P+ + + P P R+ PS K ++ P + +++ +
Sbjct: 1394 AIPS--PKGDPTSPAVIPLSPKKAPATPVTREGAATPS-KGDLTPPAVTPVSLKKAPATS 1450
Query: 707 TPELG--------------IVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRAALSPGL 752
P+ G + PP P PA Q A ++ + T A P +
Sbjct: 1451 APKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSS--SPKKAPATPAPMGAPTLPAV 1508
Query: 753 LPGV---VPQGPTELLQPLSPGPGAAGTSSDALLA----LLDPLSTAWSGSTLPSRPATP 805
+P VP P+ P++P + A LA L+ P T S P+ P
Sbjct: 1509 IPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK 1568
Query: 806 NV-ATPFTPQFSFPPAGTPTPF-------------------------------PQPPLNP 833
ATP + + S PPA TP+ + P P P
Sbjct: 1569 EAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628
Query: 834 FVPS---MPAAPPTLP--LVSTPAGP------FGAP--------PASLGPAFASGLLLSS 874
P+ P +PP P L +P P GA PA GP +L++
Sbjct: 1629 ATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP 1688
Query: 875 AG-----FCAPHRSQPNL---SALSMPNLFGQMPMGTHTSPLQPLGPPAVAPSRIRTLPL 926
A AP R P SA S P PL + P AP LP+
Sbjct: 1689 APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAP---AP----LLPV 1741
Query: 927 ARSSARAAETKQGLALRPGDPPLLPPRPPQGLEPTLQPSAPQQARDPFEDLLQKTKQ--- 983
+ S++ A+ K G PL PP + S P A FE +L K +
Sbjct: 1742 QKDSSKTAKGKDASHSPKG--PLAPPES--------KASTPLTAA-AFEKVLPKPESASV 1790
Query: 984 DVSPSP----ALAPAP 995
+PSP LAP+P
Sbjct: 1791 SAAPSPPVSLPLAPSP 1806
Score = 42.7 bits (99), Expect = 0.002
Identities = 84/334 (25%), Positives = 122/334 (36%), Gaps = 60/334 (17%)
Query: 649 PSKPPAA------SPEKPSALLGNSLA-LPRRPQNRDSILNPSDKEEV---PTP-TLGSI 697
P+ PP SP P+++ A +P+ + + P+ +EV P P + I
Sbjct: 1637 PTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPII 1696
Query: 698 TIPRPQGRKTPELGIVPPPPIPRPAKLQAAGAALGDVSER----LQTDRDRRAALSPGLL 753
T P +G +T + PP P P+ + L V+ +Q D + A G
Sbjct: 1697 TAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAK---GKD 1753
Query: 754 PGVVPQGPTELLQPLSPGPGAAGTSSDALLALLDPLSTAWSGSTLPSRPATPNVATPFTP 813
P+GP L+P A T PL+ A LP +P + +V+ +P
Sbjct: 1754 ASHSPKGP------LAPPESKAST----------PLTAAAFEKVLP-KPESASVSAAPSP 1796
Query: 814 QFSFPPAGTPTPFPQPPLNPFVPSMPA------APPTLPLVSTPAGPFGAP-PASLGPAF 866
S P A +P P PP F+PS P + P P P P P S G F
Sbjct: 1797 PVSLPLAPSPVP-TLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPF 1855
Query: 867 ASGLL----LSSAGFCAPHRS--QP-----------NLSALSMPNLFGQMPMGTHTSPLQ 909
S L+ SAG P S QP + S S+P L Q T Q
Sbjct: 1856 QSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQ 1915
Query: 910 PLGPPAVAPSRIRTLPLARSSARAAETKQGLALR 943
+ + +RS +A + L LR
Sbjct: 1916 LAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLR 1949
Score = 38.9 bits (89), Expect = 0.025
Identities = 57/200 (28%), Positives = 75/200 (37%), Gaps = 39/200 (19%)
Query: 760 GPTELLQPLSPGPGAAGTSSDALLALLDPLSTAWSGSTLPSRPATPNVATPFTPQFSFPP 819
GPT L P SP P PLS A S PS P+T +TP F
Sbjct: 42 GPT-LPPPCSPAPQQC------------PLSAANQASPFPS-PSTI-ASTPLEVPFPQSS 86
Query: 820 AGTPTPFPQPPLNP-FVPSMPAAPPTLPLVSTPAGPFGAPPASLGPAFASGLLLSSAGFC 878
+GT P P P F+P++ PP P A P AP P+ ++ L L +
Sbjct: 87 SGTALPLGTAPEAPTFLPNL-IGPPISPAALALASPMIAPTLKGTPSSSAPLALVA---L 142
Query: 879 APHRSQPNLSALSMPNLFGQMPMGTHTSPLQPLGPPAVAPSRIRTLPLARSSARAAETKQ 938
APH Q S+ PNL PP+VA + ++ + +E K
Sbjct: 143 APHSVQK--SSAFPPNLL--------------TSPPSVAVAESGSVITLSAPIAPSEPKT 186
Query: 939 GLALRPGD---PPLLPPRPP 955
L P + P P PP
Sbjct: 187 NLNKVPSEVVPNPKGTPSPP 206
Score = 37.0 bits (84), Expect = 0.094
Identities = 82/318 (25%), Positives = 113/318 (35%), Gaps = 46/318 (14%)
Query: 683 PSDKEEVPTPTLGSITIPRPQGRK-TPELG----IVPPP--PIPRPAKLQAAGAA--LGD 733
P+ ++E+P P + +P T LG +PPP P P+ L AA A
Sbjct: 10 PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPS 69
Query: 734 VSERLQTDRD---RRAALSPGLLPGVVPQGPTELLQ----PLSPG----------PGAAG 776
S T + +++ L G P+ PT L P+SP P G
Sbjct: 70 PSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKG 129
Query: 777 T-SSDALLAL--LDPLSTAWSGS------TLPSRPATPNVATPFTPQFSFPPAGTPTPFP 827
T SS A LAL L P S S + T P A + T P+ T
Sbjct: 130 TPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLN 189
Query: 828 QPPLNPFVPSMPAAPPTLPLVSTPAGPFGAPPASLGPAFASGLLLSSAGFCAPHRSQPNL 887
+ P + VP+ P +VST P AS+ AS + A Q
Sbjct: 190 KVP-SEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKD 248
Query: 888 SALSMPNLFGQMPMGTHTSPLQPLGPPAVAPSRIRTLPLARSSARAAETKQGLALRPGDP 947
+ +S + Q P S P+ PPA ++LP+ SS + A P P
Sbjct: 249 TTISSVLISPQNPGSL--SLKGPVSPPAALSLSTQSLPVVTSSQKTA--------GPNTP 298
Query: 948 PLLPPRPPQGLEPTLQPS 965
P P L P Q S
Sbjct: 299 PDFPISLGSHLAPLHQSS 316
>gi|148922920 DENN/MADD domain containing 4B [Homo sapiens]
Length = 1496
Score = 68.6 bits (166), Expect = 3e-11
Identities = 47/188 (25%), Positives = 85/188 (45%), Gaps = 7/188 (3%)
Query: 93 AKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNE--LLETLHKLPIPDPG---VSV 147
++ +LS P F F L L Y+ E + +H +P P P + V
Sbjct: 314 SRRAIAVLSRWPAFPAFRAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILV 373
Query: 148 HLSVHSYFTVPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTL 207
+S + + P + + ++ + L ++L E ++L+ + L
Sbjct: 374 QMSPYDNLLLCQPVSSPLPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLVHSLRPDLL 433
Query: 208 TACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVI 267
T+ +M++P++WQ YIP+ P L D AP+P+++GIH S + A DV+
Sbjct: 434 TSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPA--DVIC 491
Query: 268 LNVDTNTL 275
+++DTNTL
Sbjct: 492 VDLDTNTL 499
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 67.4 bits (163), Expect = 6e-11
Identities = 104/373 (27%), Positives = 137/373 (36%), Gaps = 79/373 (21%)
Query: 690 PTPTLGSITIPRPQGRKTPELGIVPPPPIPRP-AKLQAAGAALGDVSERLQTDRDRRAAL 748
PTP S + R E+G+ P P RP + ++ SE T+ A
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
Query: 749 SPGLLPGV-------VPQGPTELLQPLSPGPGAAGT------------------------ 777
P G+ + T L P GP A GT
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 286
Query: 778 --SSDALLAL----LDPLSTAWSGSTL-----PSRPATPNVATPFTPQFSFP-PAGTPTP 825
DA AL PL+T + L P+ PATP+ ++ T Q + P P P+P
Sbjct: 287 PPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH-SSSLTCQLATPLPLAPPSP 345
Query: 826 FPQPPLNPFVPSMPAAPPTLP---------------LVSTPAGPFGAPPASLGPAFASGL 870
P L +PS PA PP+ L S P P PP PA A
Sbjct: 346 SAPPSLQT-LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 404
Query: 871 LLSSAGFCAPHRSQPNLSALSMPNLFGQMPMGTH--TSPLQ-PLGPPAVAP-SRIRTLPL 926
L + +P S P LS L+ P+ + H +P P PP AP S + P+
Sbjct: 405 LQAPP---SPPASPP-LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 460
Query: 927 ARSSARAAETKQGLALRPGDPPL-LPPRPPQGLEPTLQPSA--PQQARDPF-EDLLQKTK 982
+ S+ ++ LA PPL +PP PP P + PSA P QA P LQ K
Sbjct: 461 SPSATPPSQAPPSLAA----PPLQVPPSPP--ASPPMSPSATPPPQAPPPLAAPPLQLAK 514
Query: 983 QDVSPSPALAPAP 995
PALA P
Sbjct: 515 PPPQAPPALATPP 527
Score = 61.6 bits (148), Expect = 4e-09
Identities = 135/557 (24%), Positives = 182/557 (32%), Gaps = 93/557 (16%)
Query: 467 LPKTAP--SPLVEAKDPKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRRTSVPSP 524
+P++AP P A RP G+ PP + P S+ T+ P P
Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG-RASGTTRPGP 128
Query: 525 EQPQPYRTLRESDSAEGDEAESPEQQV------RKSTGPVPAPPDRAASIDLLEDVFSNL 578
+ R E A G E+P++ R ++GP P P A
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA------------- 175
Query: 579 DMEAALQPLGQAKSLEDLRAPKDLREQPGTFDYQRLDLGGSERSRGVTVALKLTHPYNKL 638
M + G L R R +P T ++ SE S
Sbjct: 176 -MARRSRAAGTEVGLP--RPAPSARPRPPTEGPRKSVSSASEHST--------------- 217
Query: 639 WSLGQDDMAIPSKPPAASPEKPSALLG------NSLALPRRPQNRDSILNPSDKEEVPTP 692
++P A+ +PSA G SL+ P + + PS + P
Sbjct: 218 -----------TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266
Query: 693 TLGSITIPRPQGRKTPELGIVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRAAL---S 749
S P+P+G L + PP + P K A ALG +S AAL +
Sbjct: 267 AHPSQ--PKPKG-----LQALRPPQVTPPRK--DAAPALGPLSSSPLATPSPSAALQSQA 317
Query: 750 PGLLPGVVPQGPTELLQPLSPGPGAAGTSS--DALLALLDPLSTAWSGSTLPSRPATPNV 807
P LP P + Q +P P A + S +L L P +T S +T T
Sbjct: 318 PPTLPAT-PHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 376
Query: 808 ATPFTPQFSFPPAGTPTPFPQPPLNPFVPSMPAAPPTLPLVSTPAGPFGAPPASLGPAFA 867
F P P TP P P L P +PP P P P P A A
Sbjct: 377 THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP----PLSPLATPSPQAPNALA 432
Query: 868 SGLLLS----------SAGFCAPHRSQPNLSALSMPNLFGQMPMGTHTSPLQ-PLGPPAV 916
LL + A F P + P +S + P Q P PLQ P PPA
Sbjct: 433 VHLLQAPFSPPPSPPVQAPFSPP--ASPPVSPSATPP--SQAPPSLAAPPLQVPPSPPAS 488
Query: 917 APSRIRTLPLARSSARAAETKQGLALRPGDPPLLPPRPPQGLEPTLQPSAPQQARDPFED 976
P P ++ A LA P P PP P+ S P QA PF
Sbjct: 489 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA--PFSP 546
Query: 977 LLQKTKQDVSPSPALAP 993
++ P AP
Sbjct: 547 SASLPMSPLATPPPQAP 563
Score = 58.9 bits (141), Expect = 2e-08
Identities = 129/522 (24%), Positives = 175/522 (33%), Gaps = 66/522 (12%)
Query: 496 QVRPPRPHVVKRPKSNIAVEGRRTSVPSPEQ---PQPYRTLRESDSAEGDEAESPEQQVR 552
+V PRP RP+ EG R SV S + +P R SA G + +
Sbjct: 186 EVGLPRPAPSARPRP--PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
Query: 553 KSTGPVPAPPDRAASIDLLEDVFSNLDMEAALQPLGQAKSLEDLRAPKDLREQ----PGT 608
S P+ +P S A + K L+ LR P+ + P
Sbjct: 244 SSATPLSSPARSGPSA-------RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
Query: 609 FDYQRLDLGGSERSRGVTVALKLTHPYNKLWSLGQDDMAIPSKPPAASPEKPSALLGNSL 668
L S + T P S +A P SP P +L
Sbjct: 297 GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQ---- 352
Query: 669 ALPRRP-----QNRDSILNPSDKEE---VPTPTLGSITIPRPQGRKTPELGIVPPPPIPR 720
LP P Q S+ +P+ + +P+P L + P PQ L + PP P
Sbjct: 353 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 412
Query: 721 PAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPGVVPQGPTELLQPLSPGPGAAGTSSD 780
+ + A + +A SP P V P+SP +
Sbjct: 413 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472
Query: 781 ALLALLDPLSTAWSGSTLPSRPATPNVATPFTPQFSFPPAGTPTPFPQPPLNPFVPSMPA 840
+L A PL PS PA+P P +P + PP P P PPL P P
Sbjct: 473 SLAA--PPLQVP------PSPPASP----PMSPS-ATPPPQAPPPLAAPPLQLAKPP-PQ 518
Query: 841 APPTLPLVSTPAGPFGAPPASL---GPAFASGLLLSSAGFCAPHRSQPNLSALSMPNLFG 897
APP L + P +PPAS P S L S P ++ P L+A +
Sbjct: 519 APPA--LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL----- 571
Query: 898 QMPMGTHTSPLQPLGPPAVAPSRIRTLPLARSSARAAETKQGLALRPGDPPLLPPRPPQG 957
Q+P P P P AP R P + + LAL PG PP P R P
Sbjct: 572 QVP------PSPPASPTLQAP---RRPPTPGPDTSVSGPRLTLALAPGPPP-PPSRSPSS 621
Query: 958 L--EPTLQPSAPQQARDPFEDLLQKTKQDVSPSPALAPAPDS 997
P L + P E L+ A +P PD+
Sbjct: 622 TLSGPDLAGHSSSATSTPEE--LRGYDSGPEGGAAASPPPDA 661
Score = 46.2 bits (108), Expect = 2e-04
Identities = 80/311 (25%), Positives = 108/311 (34%), Gaps = 41/311 (13%)
Query: 627 VALKLTHPYNKLWSLGQDDMAIPSKPPAASPEKPSALLGNSLALPRRPQNRDSILNPSDK 686
V+ T P SL + +P PPA+ P PSA PQ + P +
Sbjct: 460 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA--------TPPPQAPPPLAAPPLQ 511
Query: 687 EEVPTPTLGSITIPRPQGRKTPELGIVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRA 746
P P P TP L +P PP P + + +A +S
Sbjct: 512 LAKPPP-------QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 564
Query: 747 ALSPGLL--PGVVPQGPT--ELLQPLSPGPGAAGTSSDALLALL--DPLSTAWSGSTLPS 800
L+ LL P P PT +P +PGP + + LAL P + S S+ S
Sbjct: 565 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 624
Query: 801 RP--ATPNVATPFTPQ----FSFPPAGTPTPFPQP-----PLNPFVPSMPAAPPTLPLVS 849
P A + + TP+ + P G P P +P S APP L
Sbjct: 625 GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPP-LAFRG 683
Query: 850 TPAGPFGAPPASLGPAFASGLLLSSAGFCAPHRSQPNLSALSMPNLFGQMPMGTHTSPLQ 909
P P PPA+ GP A GL C + ++ SA P P +
Sbjct: 684 APGAPLPWPPAT-GPGSADGL-------CTIYETEGPESATPAPGALDPGPSPGTSGGKA 735
Query: 910 PLGPPAVAPSR 920
G A A SR
Sbjct: 736 AAGAGAGASSR 746
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 66.6 bits (161), Expect = 1e-10
Identities = 94/351 (26%), Positives = 124/351 (35%), Gaps = 66/351 (18%)
Query: 618 GSERSRGVTVALKLTHPYNKLWSLGQDDMAIPSKPPAASPEKPSALLGNSLALPRRPQNR 677
GS+ ++ + +H ++ + S ++ IPS PP E S++ G + P
Sbjct: 826 GSQPPHSISTEFQTSHEHS-VSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPP----- 879
Query: 678 DSILNPSDKEEVPTPTLGSITIPRPQGRKTPELGIVPPPP-----IPRPAKLQAAGAALG 732
P + PTL S IP+P + E+ PPPP IP P L A
Sbjct: 880 -----PPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGA----- 929
Query: 733 DVSERLQTDRDRRAALSPGLLPGVVPQGPTELLQPLSPGPGAAGTSSDALLALLDPLSTA 792
G+LP +P P + P P PGAA L PL
Sbjct: 930 ------------------GILP--LPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPP 969
Query: 793 WSGSTLPSRPATPNVATPFTPQFSFPPAGTPTPFPQPPLN-PFVPSMPAA--PPTLPLVS 849
G+ +P P P P P P AG P P P P P P +P A PP PL
Sbjct: 970 LPGAGIPPPPPLPGAGIP--PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL-- 1025
Query: 850 TPAGPFGAPPASLGPAFASGLLLSSAGFCAPHRSQPNLSALSMPNLFGQMPM-GTHTSPL 908
P PP G L AG P P L +P P+ G P
Sbjct: 1026 -PGAGIPPPPPLPGAGIPPPPPLPGAGIPPP----PPLPGAGIP---PPPPLPGAGIPPP 1077
Query: 909 QPLGPPAVAPSRIRTLPLARSSARAAETKQGLALRPGDPPL----LPPRPP 955
PL + P PL + G+ + P PPL +PP PP
Sbjct: 1078 PPLPGAGIPPPP----PLPGAGIPPPPPLPGVGI-PPPPPLPGAGIPPPPP 1123
Score = 50.4 bits (119), Expect = 8e-06
Identities = 70/244 (28%), Positives = 80/244 (32%), Gaps = 58/244 (23%)
Query: 690 PTPTLGSITIPRPQGRKTPELGIVPPPP-----IPRPAKLQAAGAALGDVSERLQTDRDR 744
P P L IP P P +GI PPPP IP P L AG
Sbjct: 1087 PPPPLPGAGIPPPP--PLPGVGIPPPPPLPGAGIPPPPPLPGAGIP-------------- 1130
Query: 745 RAALSPGLLPGVVPQGPTEL----LQPLSPGPGAAGTSSDALLALLDPLSTAWSGSTLPS 800
P LPG P L + P P PGA P G+ +P
Sbjct: 1131 ----PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAG-----------IPPPPPLPGAGIPP 1175
Query: 801 RPATPNVATPFTPQFSFPPAGTPTPFPQP----PLNPFVPSM---PAAPPTLPLVSTPAG 853
P P V P P P G P P P P P P +P M PA P LP T
Sbjct: 1176 PPPLPGVGIP--PPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGT--- 1230
Query: 854 PFGAPPASLGPAFASGLLLSSAGFCAPHRSQPNLSALSMPN-LFG---QMPMGTHTSPLQ 909
G PP L P LL P +P+ LFG G+ P++
Sbjct: 1231 --GIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIE 1288
Query: 910 PLGP 913
P P
Sbjct: 1289 PCRP 1292
Score = 30.4 bits (67), Expect = 8.8
Identities = 34/130 (26%), Positives = 46/130 (35%), Gaps = 24/130 (18%)
Query: 837 SMPAAPPTLPLVSTPAGPFGAPPASLGPAF-------ASGLLLSSAGFCAPHRSQPNLSA 889
S P PP+L + P PP S+ F S +S +P S+
Sbjct: 808 SQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESS 867
Query: 890 LSMPNLFGQMPMGTHTSPLQPLGPPAVAPSRIRTLPLARSSARAAETKQGLALRPGDPPL 949
SMP L + P PP + + TLP ++ QG + P PP
Sbjct: 868 SSMPGL-----------GMVPPPPPPLPGMTVPTLP--STAIPQPPPLQGTEMLPPPPPP 914
Query: 950 LP----PRPP 955
LP P PP
Sbjct: 915 LPGAGIPPPP 924
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 65.9 bits (159), Expect = 2e-10
Identities = 96/353 (27%), Positives = 122/353 (34%), Gaps = 59/353 (16%)
Query: 650 SKPPAASPEKPSALLGNSLALPRRPQNRDSILNPSDKEEVPTPTLGSITIPRPQGRKTPE 709
S+PP P S + P P R + +P + P P + PRP P+
Sbjct: 124 SRPPLLPPGGRSTS-AKPFSPPSGP-GRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD 181
Query: 710 LGIVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPGVVPQGPTELLQPLS 769
P P PRP + + +R + PG P GPT
Sbjct: 182 SIPPPVPSTPRPIQ---------------SSPHNRGSPPVPGG-PRQPSPGPTP-----P 220
Query: 770 PGPGAAGTSSDALLALLDPLSTAWSGSTLPSRPATPNVATPFTPQFSFPPAGTPTPF--- 826
P PG GT+ PLS++ S P P TP+ A P PP G
Sbjct: 221 PFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHRE 280
Query: 827 --PQPPLNPFVPSMPAAPPTLPLVSTPAGPFGAPPASLGPAFASGLLLSSAGFC-APHRS 883
P PP P +P+ P P S+ A P PP+ GP L SS+G P
Sbjct: 281 AVPPPPPQNNKPPVPSTP--RPSASSQAPPPPPPPSRPGP---PPLPPSSSGNDETPRLP 335
Query: 884 QPNLS------ALSMPNLFGQMPMGTHTSPLQPLGPPAVAPSRIRTLPLARSSARAAETK 937
Q NLS L P G +P P P+ P P R LP +R T
Sbjct: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP---PGRSGPLPPPPPVSRNGSTS 392
Query: 938 QGLALRP--------------GDPPLLPPRPPQGLEPTLQPSAPQQARDPFED 976
+ L P PPL P RP G P PS R+ F+D
Sbjct: 393 RALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPST--SIRNGFQD 443
Score = 37.7 bits (86), Expect = 0.055
Identities = 69/269 (25%), Positives = 92/269 (34%), Gaps = 39/269 (14%)
Query: 737 RLQTDRDRRAALS-PGLLPGVVPQGPTELLQPLSP--GPGAAGTSSDALLALLDPLSTAW 793
R +RD + S P LLP P G + +P SP GPG S
Sbjct: 112 RSTANRDNDSGGSRPPLLP---PGGRSTSAKPFSPPSGPGRFPVPSPGHR---------- 158
Query: 794 SGSTLPSR----PATPNVATPFTPQFSFPPA-GTPTPFPQPPLNPFVPSMPAAPPTLPLV 848
SG P R P P+V + P PP TP P P N P +P P
Sbjct: 159 SGPPEPQRNRMPPPRPDVGSK--PDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPG 216
Query: 849 STPAGPFGAPPASLGPAFASGLLLSSA-GFCAPHRSQPNLSALSMPNLFGQMPMGTHTSP 907
TP PF P + G A G + S +P ++P L L + P P
Sbjct: 217 PTPP-PF---PGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP-----PP 267
Query: 908 LQPLGP-PAVAPSRIRTLPLARSSARAAETKQGLALRPGDPPLLPPRPPQGLEPTLQPSA 966
P+G P++ + P + T RP PP PP P P
Sbjct: 268 PPPVGNRPSIHREAVPPPPPQNNKPPVPSTP-----RPSASSQAPPPPPPPSRPGPPPLP 322
Query: 967 PQQARDPFEDLLQKTKQDVSPSPALAPAP 995
P + + L + +S S P+P
Sbjct: 323 PSSSGNDETPRLPQRNLSLSSSTPPLPSP 351
Score = 30.8 bits (68), Expect = 6.7
Identities = 31/119 (26%), Positives = 45/119 (37%), Gaps = 20/119 (16%)
Query: 499 PPRPHVVKRPKSNIAVEGRRTSVPSP----EQPQPYRTLRESDSAEGDEAESPEQQVRKS 554
PP P V RP + R +VP P +P T R S S++ P +
Sbjct: 266 PPPPPVGNRPSIH------REAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR---- 315
Query: 555 TGPVPAPPDRAASIDLLEDVFSNLDMEAALQPL------GQAKSLEDLRAPKDLREQPG 607
GP P PP + + + NL + ++ PL G R P +R+ PG
Sbjct: 316 PGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPG 374
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 65.9 bits (159), Expect = 2e-10
Identities = 96/353 (27%), Positives = 122/353 (34%), Gaps = 59/353 (16%)
Query: 650 SKPPAASPEKPSALLGNSLALPRRPQNRDSILNPSDKEEVPTPTLGSITIPRPQGRKTPE 709
S+PP P S + P P R + +P + P P + PRP P+
Sbjct: 124 SRPPLLPPGGRSTS-AKPFSPPSGP-GRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD 181
Query: 710 LGIVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPGVVPQGPTELLQPLS 769
P P PRP + + +R + PG P GPT
Sbjct: 182 SIPPPVPSTPRPIQ---------------SSPHNRGSPPVPGG-PRQPSPGPTP-----P 220
Query: 770 PGPGAAGTSSDALLALLDPLSTAWSGSTLPSRPATPNVATPFTPQFSFPPAGTPTPF--- 826
P PG GT+ PLS++ S P P TP+ A P PP G
Sbjct: 221 PFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHRE 280
Query: 827 --PQPPLNPFVPSMPAAPPTLPLVSTPAGPFGAPPASLGPAFASGLLLSSAGFC-APHRS 883
P PP P +P+ P P S+ A P PP+ GP L SS+G P
Sbjct: 281 AVPPPPPQNNKPPVPSTP--RPSASSQAPPPPPPPSRPGP---PPLPPSSSGNDETPRLP 335
Query: 884 QPNLS------ALSMPNLFGQMPMGTHTSPLQPLGPPAVAPSRIRTLPLARSSARAAETK 937
Q NLS L P G +P P P+ P P R LP +R T
Sbjct: 336 QRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP---PGRSGPLPPPPPVSRNGSTS 392
Query: 938 QGLALRP--------------GDPPLLPPRPPQGLEPTLQPSAPQQARDPFED 976
+ L P PPL P RP G P PS R+ F+D
Sbjct: 393 RALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPST--SIRNGFQD 443
Score = 37.7 bits (86), Expect = 0.055
Identities = 69/269 (25%), Positives = 92/269 (34%), Gaps = 39/269 (14%)
Query: 737 RLQTDRDRRAALS-PGLLPGVVPQGPTELLQPLSP--GPGAAGTSSDALLALLDPLSTAW 793
R +RD + S P LLP P G + +P SP GPG S
Sbjct: 112 RSTANRDNDSGGSRPPLLP---PGGRSTSAKPFSPPSGPGRFPVPSPGHR---------- 158
Query: 794 SGSTLPSR----PATPNVATPFTPQFSFPPA-GTPTPFPQPPLNPFVPSMPAAPPTLPLV 848
SG P R P P+V + P PP TP P P N P +P P
Sbjct: 159 SGPPEPQRNRMPPPRPDVGSK--PDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPG 216
Query: 849 STPAGPFGAPPASLGPAFASGLLLSSA-GFCAPHRSQPNLSALSMPNLFGQMPMGTHTSP 907
TP PF P + G A G + S +P ++P L L + P P
Sbjct: 217 PTPP-PF---PGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP-----PP 267
Query: 908 LQPLGP-PAVAPSRIRTLPLARSSARAAETKQGLALRPGDPPLLPPRPPQGLEPTLQPSA 966
P+G P++ + P + T RP PP PP P P
Sbjct: 268 PPPVGNRPSIHREAVPPPPPQNNKPPVPSTP-----RPSASSQAPPPPPPPSRPGPPPLP 322
Query: 967 PQQARDPFEDLLQKTKQDVSPSPALAPAP 995
P + + L + +S S P+P
Sbjct: 323 PSSSGNDETPRLPQRNLSLSSSTPPLPSP 351
Score = 30.8 bits (68), Expect = 6.7
Identities = 31/119 (26%), Positives = 45/119 (37%), Gaps = 20/119 (16%)
Query: 499 PPRPHVVKRPKSNIAVEGRRTSVPSP----EQPQPYRTLRESDSAEGDEAESPEQQVRKS 554
PP P V RP + R +VP P +P T R S S++ P +
Sbjct: 266 PPPPPVGNRPSIH------REAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR---- 315
Query: 555 TGPVPAPPDRAASIDLLEDVFSNLDMEAALQPL------GQAKSLEDLRAPKDLREQPG 607
GP P PP + + + NL + ++ PL G R P +R+ PG
Sbjct: 316 PGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPG 374
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 65.5 bits (158), Expect = 2e-10
Identities = 97/348 (27%), Positives = 127/348 (36%), Gaps = 76/348 (21%)
Query: 653 PAASPEKP-SALLGNSLALPRRPQNRDSILNPSDKEEVPTPTLGSITIPRPQGRKTP--- 708
P++SP P A LG+S LP R PS + V P P P + P
Sbjct: 773 PSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLP 832
Query: 709 -------ELGIVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPGVVPQGP 761
+LG+ PP P P A G + L P P P+GP
Sbjct: 833 GIFVIQNQLGVPPPASNPAPT---APGPP--------------QPPLRPQSQP---PEGP 872
Query: 762 TELLQPLSPGPGAAGTSSDALLALLDPLSTAWSGSTLPSRPATPNVATPFTPQFSFPPAG 821
L P P +S+ + +A S++ + S LP+ TP Q FPP+
Sbjct: 873 ------LPPAPHLPPSSTSSAVA-----SSSETSSRLPA-------PTPSDFQLQFPPSQ 914
Query: 822 TPTPFPQPPLNPFVPSMPAAPP-----TLPLVSTPAGPFGAPPASLG--PAFASGLLLSS 874
P P PP + PAAPP T +V+TP P A L SG++L +
Sbjct: 915 GPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQN 974
Query: 875 AGFCAPHRSQ--PNLSALSMPN----LFGQMPMGTHTSPLQPLGPPAVAPSRIRTLPLAR 928
AP Q +L L+ P + GQ P GT T+P PA AP LP
Sbjct: 975 KAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSH---APAPAPMAATGLPPLL 1031
Query: 929 SSARAAETKQGLALRPGDPPLLPPRPPQGLE-----------PTLQPS 965
+ A L P P GL+ PTLQPS
Sbjct: 1032 PAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPS 1079
Score = 64.7 bits (156), Expect = 4e-10
Identities = 98/339 (28%), Positives = 120/339 (35%), Gaps = 57/339 (16%)
Query: 649 PSKPPAASPEKPSALLGNS-LALPRRPQNRDSI--LNPSDKEEVPTPTLGS-ITIPRPQG 704
PS A+SPEK +LG A P +DS+ P ++ + P G +++P
Sbjct: 666 PSPGLASSPEK--IVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVI 723
Query: 705 RKTPELGIVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPGVVPQGPTEL 764
P PP P PA A GA LG + Q SP P + P +
Sbjct: 724 VSAP-----PPAQDPAPATPVAKGAGLGPQAPDSQA--------SPAPAPQIPAAAPLK- 769
Query: 765 LQPLSPGPGAAGTSSDALLALLDPLSTAWSGSTLPS-RPATPNVATPFTPQ-FSFPPAGT 822
PGP SS L PL + LPS P P P PQ S PP+
Sbjct: 770 ----GPGP-----SSSPSLPHQAPLGDS---PHLPSPHPTRPPSRPPSRPQSVSRPPS-- 815
Query: 823 PTPFPQPPLNPFVPSMPAAPPTLPLVSTPAGPFGAPPASLGPAFASGLLLSSAGFCAPHR 882
+PPL+P P P APPTLP + G PP + PA AP
Sbjct: 816 -----EPPLHPCPP--PQAPPTLPGIFVIQNQLGVPPPASNPAPT-----------APGP 857
Query: 883 SQPNLSALSMPNLFGQMPMGTHTSPLQPLGPPAVAPSRIRTLPLARSSARAAE--TKQGL 940
QP L S P G +P H P A + LP S + QG
Sbjct: 858 PQPPLRPQSQPPE-GPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGP 916
Query: 941 ALRPGDPPLLPPRPPQGLEPTLQPSAPQQARDPFEDLLQ 979
P PP L P P P Q PF L Q
Sbjct: 917 HKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQ 955
Score = 60.8 bits (146), Expect = 6e-09
Identities = 110/427 (25%), Positives = 159/427 (37%), Gaps = 80/427 (18%)
Query: 642 GQDDMAIPSKPPAASPEKPSAL---LGNSLALPRRPQNRDSIL-NP--SDKEEVPTPTLG 695
GQ+ +P P P++ SAL +G + P ++ NP +++ +LG
Sbjct: 468 GQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLG 527
Query: 696 SITIPRPQGRKTPELGIVPPPPIPRPAKLQA-AGAALGDVSERLQTDRDRRAALSPGLLP 754
+ P G + + P + +PA Q A G + + Q AA + +L
Sbjct: 528 PVLAPH-SGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATT--VLQ 584
Query: 755 GVV--PQG------PTELLQPLSPGPGAAGTSSDALLALLDPLSTAWSGSTLPSRPATPN 806
GV P P L+QP +P A G ++ L P + + LP P
Sbjct: 585 GVTLPPSAVAMLNTPDGLVQPATPA-AATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQ 643
Query: 807 VATPF---TPQFSFPP-AGTPTPFP------------QPP------------LNPFVPSM 838
P TPQ + PP A TP P P QPP L F+P
Sbjct: 644 AQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQE 703
Query: 839 PAAPPTL---PLVSTPAGPF-GAPPASLGPAFASGLLLSSA-GFCAPHRSQPNLSALSMP 893
+ P P +S PA APP + PA A+ + + G AP A +P
Sbjct: 704 RSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIP 763
Query: 894 N---LFGQMPMGTHTSPLQ-PLGPPAVAPSRIRTLPLARSSARAAETKQGLALRPGDPPL 949
L G P + + P Q PLG PS T P +R +R Q ++ P +PPL
Sbjct: 764 AAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRP----QSVSRPPSEPPL 819
Query: 950 LPPRPPQGLEPTL-------------------QPSAPQQARDPFEDLLQKTKQDVSPSPA 990
P PPQ PTL P+AP + P Q + + P+P
Sbjct: 820 HPCPPPQA-PPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPH 878
Query: 991 LAPAPDS 997
L P+ S
Sbjct: 879 LPPSSTS 885
Score = 52.0 bits (123), Expect = 3e-06
Identities = 91/362 (25%), Positives = 120/362 (33%), Gaps = 65/362 (17%)
Query: 640 SLGQDDMAIPSKPPAASPEKPSALLGNSLALPRRPQNRDSILNPSDKEEVP-TPTLGSIT 698
SL + S+P A P + L G +L P + ++LN D P TP +
Sbjct: 560 SLAAGSLPTQSQPAPAGPAATTVLQGVTL-----PPSAVAMLNTPDGLVQPATPAAAT-- 612
Query: 699 IPRPQGRKTPELGIVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPGVVP 758
G P L + P P P PA VS L + A P P
Sbjct: 613 -----GEAAPVLTVQPAPQAP-PA-----------VSTPLPLGLQQPQAQQPPQAPTPQA 655
Query: 759 QGPTELLQPLSPGPGAAGTSSDALLALLDPLSTAWSG---------------STLPSRPA 803
P + P P PG A SS + L P S + S P
Sbjct: 656 AAPPQATTP-QPSPGLA--SSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAE 712
Query: 804 TPNVATPFTPQFSFPPAGTPTPFPQPP------LNPFVPSMPAAPPTLPLVSTPAGPFGA 857
P+++ P + S PP P P P L P P A+P P + A G
Sbjct: 713 GPHLSVPASVIVSAPPPAQD-PAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGP 771
Query: 858 PPASLGPAFASGLLLSSAGFCAPHRSQPNLSALSMPNLFGQMPMGTHTSPLQPLGPPAVA 917
P+S L S +PH ++P S P + P PL P PP
Sbjct: 772 GPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPS---EPPLHPCPPPQAP 828
Query: 918 PS---------RIRTLPLARSSARAAETKQGLALRPGDPPLLPPRPPQGLEPTLQPSAPQ 968
P+ ++ P A + A A LRP P P PP P L PS+
Sbjct: 829 PTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPA---PHLPPSSTS 885
Query: 969 QA 970
A
Sbjct: 886 SA 887
Score = 32.3 bits (72), Expect = 2.3
Identities = 50/212 (23%), Positives = 69/212 (32%), Gaps = 49/212 (23%)
Query: 642 GQDDMAIPSKPPAASPEKPSALLGNSLALPRRPQNRDSILNPSDKEEVPT-PTLGSITIP 700
GQ + + PPAA KP + LP R R+++ P E P G P
Sbjct: 1357 GQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAP 1416
Query: 701 RPQGRKTPELGIV----------------PPPPIPRPAKLQAAGAALGDVSERLQTDRDR 744
P G++ PPP P + Q G D D
Sbjct: 1417 LPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTG------------DPDW 1464
Query: 745 RAALSPGLLPGVVPQGPTELLQPLSPGPGAAGTSSDA---------LLALLDPLSTAWSG 795
A PGL P + + SP A SSD+ L + +D +
Sbjct: 1465 EA---PGL-------PPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQA 1514
Query: 796 STLPSRPATPNVATPFTPQFSFPPAGTPTPFP 827
P+ P+ A+ TP S PP P +P
Sbjct: 1515 PGRTPAPSYPHAASAGTPA-SPPPLHRPEAYP 1545
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 64.3 bits (155), Expect = 5e-10
Identities = 100/386 (25%), Positives = 133/386 (34%), Gaps = 70/386 (18%)
Query: 501 RPHVVKRPKSNIAVEGRRTSVPSPEQPQPYRTLRESDSAEGDEAESPEQQVRKSTGPVPA 560
RP ++ P + VE S PE+P S EG SPE ++ P
Sbjct: 1203 RPSMLDEPPLPVGVEEPADSREPPEEP--------GLSQEGAMLLSPEPPAKEVEARPPL 1254
Query: 561 PPDRAASIDLLEDVFSNLDMEAALQPLGQAKSLEDLRAPKDLRE--QPGTFDYQRLD--- 615
P+RA DL + + + LQP L R P+ +P T D
Sbjct: 1255 SPERAPEHDLEVEPEPPMMLPLPLQP-----PLPPPRPPRPPSPPPEPETTDASHPSVPP 1309
Query: 616 -------------LGGSERSRGVTVALKLTHPYNKLWSLGQDDMAIPSKPPAASP---EK 659
L GS T + T S G +++ S SP
Sbjct: 1310 EPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPA 1369
Query: 660 PSALLGNSLALPRRPQNRDSILNPSDKEEVPTPTLGSITIPRPQGRKTPELGIVPPP--- 716
PS L + LPR P RD P+ E P+ L P P GR+ G + P
Sbjct: 1370 PSPSLSSG-GLPRTP-GRDFSFTPTFSE--PSGPLLLPVCPLPTGRRDERSGPLASPVLL 1425
Query: 717 ------PIPRPAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPGVVPQGPTELLQPLSP 770
P+P P L A A+ R A +P LP ++P P+
Sbjct: 1426 ETGLPLPLPLPLPLPLALPAVL-----------RAQARAPTPLPPLLPAPLASCPPPMKR 1474
Query: 771 GPGAAGTSSDALLALLDPLSTAWSGSTL----------PSRPATPNVATPFTPQFSFPPA 820
PG S ++L+L PL +G+ L P P P+ P T F A
Sbjct: 1475 KPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNA 1534
Query: 821 GTPTPFPQPPLNPFVPSMPAAPPTLP 846
G P P PPL P P P PP P
Sbjct: 1535 GIPAP--PPPLPPQPPPPPPPPPVEP 1558
Score = 59.7 bits (143), Expect = 1e-08
Identities = 129/542 (23%), Positives = 183/542 (33%), Gaps = 125/542 (23%)
Query: 515 EGRRTSVPSPEQPQPYRTLRESDSAEGDEAESPEQQVRKSTGPVPAPPDRAASIDLLEDV 574
E S PS + + RE + E +E E ++ S GP ED
Sbjct: 1122 ESSSESSPSSSEDEEEVVAREEEEEE-EEEEMVAEESMASAGP--------------ED- 1165
Query: 575 FSNLDMEAALQPLGQAKSLEDLRAPKDLR-------EQPGTFDYQRLDLGGSERSRGVTV 627
F EAAL P A + D+ E+P D L +G E +
Sbjct: 1166 FEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADS--- 1222
Query: 628 ALKLTHPYNKLWSLGQDDMAIPSKPPAASPEKPSALLGNSLALPRRPQNRDSILNPSDKE 687
P + + M + +PPA E L P R D + P
Sbjct: 1223 ----REPPEEPGLSQEGAMLLSPEPPAKEVEARPPLS------PERAPEHDLEVEPEPPM 1272
Query: 688 EVPTPTLGSITIPRPQGRKTPELGIVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRAA 747
+P P + PRP PP P P P A+ ++ E L D
Sbjct: 1273 MLPLPLQPPLPPPRPPR---------PPSPPPEPETTDASHPSVPP--EPLAEDHPPH-- 1319
Query: 748 LSPGLLPGVVPQGPTELLQPLSPGP------GAAGTSSDALLALLDPLSTAWSGSTLPSR 801
+PGL + TE + P +PG G++G S + P S +L S
Sbjct: 1320 -TPGLCGSLAKSQSTETV-PATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSG 1377
Query: 802 --PATPNVATPFTPQFSFPPA-----------------------------GTPTPFPQP- 829
P TP FTP FS P G P P P P
Sbjct: 1378 GLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPL 1437
Query: 830 PLNPFVPSMPAAPPTLPLVSTPAGPFGAPPASLGPAFASGLLLSSAGFCAPHRSQPNLSA 889
PL +P++ A P P P AP AS P + G P RS P++ +
Sbjct: 1438 PLPLALPAVLRAQARAPTPLPPLLP--APLASCPPP-----MKRKPG--RPRRSPPSMLS 1488
Query: 890 LSMPNLFGQMPMGTHTS------PLQPLGPPAVAPSRIRTLPLARSSARAAETKQGLALR 943
L P + + P G P QP P + RT+ L +A
Sbjct: 1489 LDGPLV--RPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGI---------- 1536
Query: 944 PGDPPLLPPRPPQGLEPTLQPSAPQQARDPFEDLLQKTKQDVSPSPALAPAPDSVEQLRK 1003
P PP LPP+PP P P + + PF++L + PS A+ P P +++ +
Sbjct: 1537 PAPPPPLPPQPP----PPPPPPPVEPTKLPFKEL-----DNQWPSEAIPPGPRGRDEVTE 1587
Query: 1004 QW 1005
++
Sbjct: 1588 EY 1589
Score = 55.1 bits (131), Expect = 3e-07
Identities = 107/394 (27%), Positives = 147/394 (37%), Gaps = 58/394 (14%)
Query: 499 PPRPHVVKRPKSNIAVEGRRTSV----PSPEQPQPYRTLRESDSAEGDEAESPEQ----- 549
PP P A +T V P PE+P DS E A +P
Sbjct: 382 PPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAE 441
Query: 550 ---QVRKSTGPVPAPPDRAASIDLLEDVFSNLDMEAALQPLGQAKSLEDLRAPKDLREQP 606
+ + T P P PPD S++L E P +LE A E+P
Sbjct: 442 PLAKEKPGTPPGPPPPD-TNSMELGGRPTFGWSPEPCDSP--GTPTLESSPAGP---EKP 495
Query: 607 GTFDYQRLDLGGSERSRGVTVALKLTHPYNKLWSLGQDDMAIPSKPPAASPEKPSALLGN 666
R+++ E+ T L L P + L + I S SP P N
Sbjct: 496 HDSLDSRIEMLLKEQR---TKLLFLREPDSDT-ELQMEGSPISSSSSQLSPLAPFGT--N 549
Query: 667 SLALPRRPQNRDSILNPSDKEEV-PTPTLGSITIPRPQGRKTPELGIVPPPPI----PRP 721
S R P S + + E++ PTP +P + +LG+ P PP P P
Sbjct: 550 SQPGFRGPTPPSSRPSSTGLEDISPTP------LPDSDEDEELDLGLGPRPPPEPGPPDP 603
Query: 722 AKL--QAAGAALGDVSERLQT----DRDRRAA-----LSPGLLPGVVPQGPTELLQPLSP 770
A L Q A AL V +R T D ++++ +S +P P + +P+
Sbjct: 604 AGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSA-PITSADCPKPMVV 662
Query: 771 GPGAAGTSSDALLALLDPLSTAWSGSTLPSRPATPNVATPFTPQFSFPPAGTPTPFPQPP 830
PGAA ++ ++LA PL LP P P P P F PP P P P PP
Sbjct: 663 TPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPP----PPQPGFPMPPPLPPPPPPPPP 718
Query: 831 LNPFV----PSMPAAPPT-LPLVSTPAGPFGAPP 859
+P V P +PA P P + P PF PP
Sbjct: 719 AHPAVTVPPPPLPAPPGVPPPPILPPLPPF--PP 750
Score = 38.9 bits (89), Expect = 0.025
Identities = 57/226 (25%), Positives = 72/226 (31%), Gaps = 41/226 (18%)
Query: 772 PGAAGTSSDALLALLDPLSTAWSGSTLPSRPATPNVATPFTPQFSFPPAGTPTPFPQPPL 831
P A T + + P T + P P P F + S P P P PP
Sbjct: 383 PPAQATPAPGFKSAFSPYQTPVAH--FPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPA 440
Query: 832 NPFVPSMPAAPPTLPLVSTPAGPFGAPPA---SLGPAFASG---LLLSSAGFCAPHRS-- 883
P P PP P T + G P S P + G L S AG PH S
Sbjct: 441 EPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLD 500
Query: 884 ----------QPNLSALSMPNLFGQMPM--------GTHTSPLQPLGPPAVAPSRIRTLP 925
+ L L P+ ++ M + SPL P G + R T P
Sbjct: 501 SRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPP 560
Query: 926 LARSSARAAE-------------TKQGLALRPGDPPLLPPRPPQGL 958
+R S+ E + L L P PP P P GL
Sbjct: 561 SSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGL 606
Score = 38.1 bits (87), Expect = 0.042
Identities = 86/347 (24%), Positives = 104/347 (29%), Gaps = 117/347 (33%)
Query: 655 ASPEKPSALLGNSLALPRRPQNRDSIL--NPSDKEEV-----PTPTLGSITIP-RPQGRK 706
A PEKP L + + + + Q + P E+ P + S P P G
Sbjct: 490 AGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTN 549
Query: 707 TPELGIVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRAALSPGLLPGVVPQGPTELLQ 766
+ P PP RP+ L D+S D D L GL P P+
Sbjct: 550 SQPGFRGPTPPSSRPSS-----TGLEDISPTPLPDSDEDEELDLGLGPRPPPE------- 597
Query: 767 PLSPGP-GAAGTSSDALLALLD------PLSTAW-------------SGSTLPSRPAT-- 804
PGP AG S LD P S S +PS P T
Sbjct: 598 ---PGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSA 654
Query: 805 ----PNVATPFTPQFSFPPAGTPT-PFPQPPLNPFVPSMPAAPPTLPLVSTPAGPFGAPP 859
P V TP + P PT P P PP P +P P PP P P P PP
Sbjct: 655 DCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPP-PLPPPP 713
Query: 860 ASLGPAFASGLLLSSAGFCAPHRSQPNLSALSMPNLFGQMPMGTHTSPLQPL-GPPAVAP 918
P + P + T P PL PP V P
Sbjct: 714 PP------------------PPPAHPAV-----------------TVPPPPLPAPPGVPP 738
Query: 919 SRIRTLPLARSSARAAETKQGLALRPGDPPLLPPRP--PQGLEPTLQ 963
PP+LPP P P GL P +Q
Sbjct: 739 ----------------------------PPILPPLPPFPPGLFPVMQ 757
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 63.9 bits (154), Expect = 7e-10
Identities = 138/563 (24%), Positives = 192/563 (34%), Gaps = 125/563 (22%)
Query: 461 PTPEEQLPKTAPSPLVEAKDPKLREDRRPIT-VHFGQVRPPRPH---------VVKRPKS 510
P P P P+ L RED + + FG PPRP + P S
Sbjct: 472 PCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPAS 531
Query: 511 NIAVEGRRTSVPSPEQPQPYRTLRESDSAEGDEAESPEQQVRKSTGPVPAPPDRAASIDL 570
+V G + S P P P T S+S G + SP GPV PP
Sbjct: 532 RFSV-GTQDSHTPPTPPTP--TTSSSNSNSGSHSSSP-------AGPVSFPP-------- 573
Query: 571 LEDVFSNLDMEAALQPLGQAKSLEDLRAPKDLREQPGTFDYQRLDLGGSERSRGVTVALK 630
P A+S++ L P + P L L
Sbjct: 574 ---------------PPYLARSIDPLPRPPSPAQNPQDPPLVPLTL-------------- 604
Query: 631 LTHPYNKLWSLGQDDMAIPSKPPAASPEKPSALLGNSLALPRRPQNRDSILNPSDKEEVP 690
A+P PP++ + S S P P+ R S P E P
Sbjct: 605 ----------------ALPPAPPSSCHQNTSG----SFRRPESPRPRVSF--PKTPEVGP 642
Query: 691 TPTLGSITI---PRPQG-----RKTPELGIVPPPPIP----RPAKLQAAGAALGDVSERL 738
P G ++ P P G + P L PP P+ PA+ + L ++ + L
Sbjct: 643 GPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKML 702
Query: 739 QTDRDRRAALSPGLLPGVVPQGPTE----LLQPLSPGPGAAGTSSDALLALLDPLSTAWS 794
+ R+ GV PQ P + LQ P A T++ A+ +T +
Sbjct: 703 D-ESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTT 761
Query: 795 GSTLPSRPATPNVATPFTPQFSFPPAGTPTPFPQPPLNP--FVPSMPAA--------PPT 844
+T P P P FPP P P P PP +P + S+ + T
Sbjct: 762 TATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGT 821
Query: 845 LPLVSTPAGPFGAPPASLG-PAFASGLLLSSAGFCAPHRSQPNLSALSM----------P 893
VST GP S G P+ A+ L +SA A QP+ S+ S
Sbjct: 822 GAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARE 881
Query: 894 NLFGQMPMGTHTSPLQPLGPPAVAPSRIRTLPLARSSARAAETKQGLALRPGDPPLLPPR 953
G+ P+ +P QP P ++ P+R + L S RA ET L R G P
Sbjct: 882 RRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEIS-RACET---LVERVGRSATDPAD 937
Query: 954 PPQGLEP----TLQPSAPQQARD 972
P EP T + P QA++
Sbjct: 938 PVDTAEPADSGTERLLPPAQAKE 960
Score = 39.7 bits (91), Expect = 0.014
Identities = 49/183 (26%), Positives = 64/183 (34%), Gaps = 40/183 (21%)
Query: 814 QFSFPPAGTPTPFPQPPLNPFVPSMPAAPPTLPLVSTPAGPFGAPPASLGPAFASGLLLS 873
Q PP P P PPL P P P PP LP ++T +PP L
Sbjct: 237 QTGLPPG---LPLPPPPLPPPPPPPPPPPPPLPGLAT------SPPFQL----------- 276
Query: 874 SAGFCAPHRSQPNLSALSMPNLFGQMPMGTHTSPLQPLGPPAVAPSRIRTLPLARSSARA 933
++P L + + +G G+ PP R +LP
Sbjct: 277 ---------TKPGLWSTLHGDAWGPERKGS--------APPERQEQR-HSLPHPYPYPAP 318
Query: 934 AETKQ--GLALRPGDPPLLPPRPPQGLEPTLQPSAPQQARDPFEDLLQKTKQDVSPSPAL 991
A T G L P PP PRPP P+ D E +Q+++ D S SPA
Sbjct: 319 AYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAA 378
Query: 992 APA 994
A
Sbjct: 379 TTA 381
Score = 39.7 bits (91), Expect = 0.014
Identities = 54/191 (28%), Positives = 69/191 (36%), Gaps = 24/191 (12%)
Query: 794 SGSTLPSRPATPNVATPFTPQFS-FPPAGTPTPFPQPPLNPFVPSMPAAPPTL-PLVSTP 851
SGS P V+ P TP+ PP G + PQP + P V +PA P L TP
Sbjct: 619 SGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQP-VPPGVGELPARGPRLFDFPPTP 677
Query: 852 AGPFGAPPAS---LGPAFASGLLLSSAGFCAPHRSQPNLSA------LSMPNLFGQMPMG 902
PA L A+ + + Q + + L P Q P
Sbjct: 678 LEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFP 737
Query: 903 THTSPLQPLGPPAVAPSRIRTLPLARSSARAAETKQGLALRPGDPPLLPPRPPQGLEPTL 962
T T+P PAVA + T ++ + E K PP LPP PP P
Sbjct: 738 TDTAPTTTA--PAVAVTTTTTTTTTTTATQEEEKK--------PPPALPPPPPLAKFP-- 785
Query: 963 QPSAPQQARDP 973
PS PQ P
Sbjct: 786 PPSQPQPPPPP 796
Score = 38.5 bits (88), Expect = 0.032
Identities = 103/444 (23%), Positives = 144/444 (32%), Gaps = 122/444 (27%)
Query: 648 IPSKPPAASPEKPSALLGNSLALPRRPQN--RDSILNPSDKEEVPTPTLGSITIP----R 701
+P+ PP P P A L R P + R+S + S + +P + +P R
Sbjct: 330 VPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSR 389
Query: 702 PQG-------------RKTPELGIVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRAAL 748
P G T G+ P P IP Q + + R
Sbjct: 390 PPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPF 449
Query: 749 --SPGLLPGV-VPQGPTE--------LLQPLSPGPGAAGTSSDALLALLDPLSTAWSGST 797
+P P + +P GP+ LL+P P G + A + L + G+
Sbjct: 450 LGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTE 509
Query: 798 LPSRPATPNVA------------------------TPFTPQ------------------F 815
P RPA P + TP TP
Sbjct: 510 GPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPV 569
Query: 816 SFPP----AGTPTPFPQPPLN-------PFVPSMPAAPPTLPLVSTPAGPFGAPPASLGP 864
SFPP A + P P+PP P VP A PP APP+S
Sbjct: 570 SFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP-------------APPSSCHQ 616
Query: 865 AFASGLLLSSAGFCAPHRSQPNLSALSMPNLFGQMPMGTHTSPLQPLGPPAVA--PSRIR 922
+S F P +P +S P + P G + QP+ PP V P+R
Sbjct: 617 N-------TSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPV-PPGVGELPARGP 668
Query: 923 TL------PLARSSARAAETK---QGLA--LRPGDPPLLPPRPPQGLEPTLQPSAPQQAR 971
L PL AE K GLA ++ D + Q E + P P +
Sbjct: 669 RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPP--LK 726
Query: 972 DPFEDLLQKTKQDVSP---SPALA 992
+PF L D +P +PA+A
Sbjct: 727 EPFASLQSPFPTDTAPTTTAPAVA 750
Score = 38.1 bits (87), Expect = 0.042
Identities = 96/406 (23%), Positives = 128/406 (31%), Gaps = 106/406 (26%)
Query: 629 LKLTHPYNKLWSLGQDDMAIPSKPPAASPEKPSALLGNSLALPRRPQNRDSILNPSDKEE 688
L L H N G + ++PP P P+AL G S + L+P K
Sbjct: 180 LHLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPS---------GEEGLSPGGKRR 230
Query: 689 VPTPTLGSITIPRPQGRKTPELGIVPPPPIPRPAKLQAAGAALGDVSERLQTDRDRRAAL 748
S P G P + PPPP P P
Sbjct: 231 ---RGCNSEQTGLPPGLPLPPPPLPPPPPPPPP--------------------------- 260
Query: 749 SPGLLPGVVPQGPTELLQP--------LSPGPGAAGTSSDALLALLDPLSTAWSGSTLPS 800
P LPG+ P +L +P + GP G++ P +LP
Sbjct: 261 PPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSA---------PPERQEQRHSLPH 311
Query: 801 RPATPNVA-TPFTPQFSFPPAGTPTPFPQPPLNPFVPSMPAAPP---------------- 843
P A T P PA P P P+PP +PA P
Sbjct: 312 PYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMD 371
Query: 844 --TLPLVSTPAGPF--GAPPASLGPAFASGLLLSS-AGF--CAPHRSQPNLSALSMPNL- 895
P +T P+ PP G +S SS G P+ P P L
Sbjct: 372 SSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALE 431
Query: 896 ---FGQMPMGTHTSPLQPLGPPAVAPSRIRTLPLARSSARAAETKQGLALRPGDPP---- 948
G++ H+S LG PA P +LP SS P PP
Sbjct: 432 VSHHGRLGPSAHSSRKPFLGAPAATPH--LSLPPGPSS-------------PPPPPCPRL 476
Query: 949 LLPPRPPQGLE-PTLQPSAPQQARDPFEDLLQKTKQDVSPSPALAP 993
L PP PP L+ P + A ++ + E+L T+ P+P P
Sbjct: 477 LRPPPPPAWLKGPACR--AAREDGEILEELFFGTEGPPRPAPPPLP 520
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,878,315
Number of Sequences: 37866
Number of extensions: 2953733
Number of successful extensions: 26852
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 196
Number of HSP's successfully gapped in prelim test: 1248
Number of HSP's that attempted gapping in prelim test: 15515
Number of HSP's gapped (non-prelim): 7548
length of query: 1009
length of database: 18,247,518
effective HSP length: 112
effective length of query: 897
effective length of database: 14,006,526
effective search space: 12563853822
effective search space used: 12563853822
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.