Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 54860079
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54860079 nadrin isoform 1 [Homo sapiens]
(881 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54860079 nadrin isoform 1 [Homo sapiens] 1796 0.0
gi|54860105 nadrin isoform 2 [Homo sapiens] 1523 0.0
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 696 0.0
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 468 e-131
gi|23510413 sorting nexin 26 [Homo sapiens] 124 5e-28
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa... 117 4e-26
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa... 117 6e-26
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 117 6e-26
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 114 4e-25
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 109 1e-23
gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens] 108 3e-23
gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens] 108 3e-23
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 107 4e-23
gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sap... 107 6e-23
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap... 107 6e-23
gi|156071465 Rho GTPase activating protein 4 [Homo sapiens] 105 2e-22
gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapi... 103 9e-22
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 102 2e-21
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 101 3e-21
gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapi... 100 5e-21
gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapi... 100 5e-21
gi|163965366 nascent polypeptide-associated complex alpha subuni... 100 5e-21
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 100 6e-21
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 100 6e-21
gi|21314774 T-cell activation Rho GTPase-activating protein isof... 100 8e-21
gi|4505507 oligophrenin 1 [Homo sapiens] 100 8e-21
gi|229094128 active breakpoint cluster region-related protein i... 99 2e-20
gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens] 99 2e-20
gi|38679957 active breakpoint cluster region-related protein is... 99 2e-20
gi|38679954 active breakpoint cluster region-related protein is... 99 2e-20
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 1796 bits (4653), Expect = 0.0
Identities = 881/881 (100%), Positives = 881/881 (100%)
Query: 1 MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSICHHSHKRLVACFQGQHGT 60
MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSICHHSHKRLVACFQGQHGT
Sbjct: 1 MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSICHHSHKRLVACFQGQHGT 60
Query: 61 DAERRHKKLPLTALAQNMQEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIV 120
DAERRHKKLPLTALAQNMQEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIV
Sbjct: 61 DAERRHKKLPLTALAQNMQEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIV 120
Query: 121 DPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEM 180
DPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEM
Sbjct: 121 DPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEM 180
Query: 181 DEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKTLPEMRAH 240
DEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKTLPEMRAH
Sbjct: 181 DEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKTLPEMRAH 240
Query: 241 QDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLK 300
QDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLK
Sbjct: 241 QDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLK 300
Query: 301 AALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDL 360
AALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDL
Sbjct: 301 AALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDL 360
Query: 361 WRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMA 420
WRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMA
Sbjct: 361 WRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMA 420
Query: 421 AATSVHVVAVIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSSNHSFHTGNDSDSGTLERK 480
AATSVHVVAVIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSSNHSFHTGNDSDSGTLERK
Sbjct: 421 AATSVHVVAVIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSSNHSFHTGNDSDSGTLERK 480
Query: 481 RPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGSTVVPAGP 540
RPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGSTVVPAGP
Sbjct: 481 RPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGSTVVPAGP 540
Query: 541 EPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASG 600
EPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASG
Sbjct: 541 EPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASG 600
Query: 601 QNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTS 660
QNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTS
Sbjct: 601 QNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTS 660
Query: 661 QHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPT 720
QHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPT
Sbjct: 661 QHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPT 720
Query: 721 QATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLA 780
QATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLA
Sbjct: 721 QATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLA 780
Query: 781 GGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIVTDS 840
GGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIVTDS
Sbjct: 781 GGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIVTDS 840
Query: 841 NSRVSEPHRSIFPEMHSDSASKDVPGRILLDIDNDTESTAL 881
NSRVSEPHRSIFPEMHSDSASKDVPGRILLDIDNDTESTAL
Sbjct: 841 NSRVSEPHRSIFPEMHSDSASKDVPGRILLDIDNDTESTAL 881
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 1523 bits (3943), Expect = 0.0
Identities = 774/881 (87%), Positives = 783/881 (88%), Gaps = 78/881 (8%)
Query: 1 MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSICHHSHKRLVACFQGQHGT 60
MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSICHHSHKRLVACFQGQHGT
Sbjct: 1 MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSICHHSHKRLVACFQGQHGT 60
Query: 61 DAERRHKKLPLTALAQNMQEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIV 120
DAERRHKKLPLTALAQNMQEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIV
Sbjct: 61 DAERRHKKLPLTALAQNMQEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIV 120
Query: 121 DPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEM 180
DPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEM
Sbjct: 121 DPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEM 180
Query: 181 DEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKTLPEMRAH 240
DEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKTLPEMRAH
Sbjct: 181 DEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKTLPEMRAH 240
Query: 241 QDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLK 300
QDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLK
Sbjct: 241 QDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLK 300
Query: 301 AALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDL 360
AALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDL
Sbjct: 301 AALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDL 360
Query: 361 WRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMA 420
WRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMA
Sbjct: 361 WRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMA 420
Query: 421 AATSVHVVAVIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSSNHSFHTGNDSDSGTLERK 480
AATSVHVVAVIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSSNHSFHTGNDSDSGTLERK
Sbjct: 421 AATSVHVVAVIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSSNHSFHTGNDSDSGTLERK 480
Query: 481 RPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGSTVVPAGP 540
RPASMAVMEGDLVKKES PP P S VPA
Sbjct: 481 RPASMAVMEGDLVKKES---------------------------PPKPKDPVSAAVPA-- 511
Query: 541 EPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASG 600
P + ++ +SG ++AG + Q++ G
Sbjct: 512 ---PGRNNSQIASGQNQPQAAAG------------------------------SHQLSMG 538
Query: 601 QNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTS 660
QP AAG PSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTS
Sbjct: 539 --QPHNAAG--------------PSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTS 582
Query: 661 QHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPT 720
QHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPT
Sbjct: 583 QHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPT 642
Query: 721 QATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLA 780
QATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLA
Sbjct: 643 QATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLA 702
Query: 781 GGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIVTDS 840
GGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIVTDS
Sbjct: 703 GGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIVTDS 762
Query: 841 NSRVSEPHRSIFPEMHSDSASKDVPGRILLDIDNDTESTAL 881
NSRVSEPHRSIFPEMHSDSASKDVPGRILLDIDNDTESTAL
Sbjct: 763 NSRVSEPHRSIFPEMHSDSASKDVPGRILLDIDNDTESTAL 803
>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
Length = 818
Score = 696 bits (1795), Expect = 0.0
Identities = 393/772 (50%), Positives = 503/772 (65%), Gaps = 49/772 (6%)
Query: 1 MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSICHHSHKRLVACFQGQHGT 60
MKKQFNRM+QLANQTVGRAEKTEVLSEDLLQ+E+RL+ V+ + H +HK+L AC QGQ G
Sbjct: 1 MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGA 60
Query: 61 DAERRHKKLPLTALAQNMQEASTQL-EDSLLGKMLETCGDAENQLALELSQHEVFVEKEI 119
+A++R KKLPLT LAQ + E S L +D+LLGKML+ CG+ E++LA EL E+ VE+++
Sbjct: 61 EADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDV 120
Query: 120 VDPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSG--TNFQGLPSKIDTLK 177
++PL+ +AEVEIPNIQKQRK LA+LVLD DS R RW Q KSSG ++ Q +K D L+
Sbjct: 121 IEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQQTSKSSGLSSSLQPAGAKADALR 180
Query: 178 EEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKTLPEM 237
EEM+EA N+VE C+DQL+ADMY+F+AKE +Y +F TL+E QA+YHRK+L +L+ LP++
Sbjct: 181 EEMEEAANRVEICRDQLSADMYSFVAKEIDYANYFQTLIEVQAEYHRKSLTLLQAVLPQI 240
Query: 238 RAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLK 297
+A Q+ W EKP+FG PLEEHL SGREIA PIEACV +LLE GM+EEGLFR+ ASKLK
Sbjct: 241 KAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLK 300
Query: 298 KLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKL 357
KLKAALDC + E+ +DPHA+AGALKSYLRELPEPLMTF LY+EW Q ++VQ+QDKKL
Sbjct: 301 KLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKL 360
Query: 358 QDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLA 417
Q LW C+KLP N N RYLIKFL+KL++ DVNKMTPSN+AIVLGPNLLW + EG +
Sbjct: 361 QALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNIT 420
Query: 418 EMAAATSVHVVAVIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSSNHSFHTGNDSDSGTL 477
EM S+ +V +IEPIIQHADWFFP E+EFN++ + + N ++ + D
Sbjct: 421 EMMTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGNYGSPVHVNHNANYSSMPSPDMDPA 480
Query: 478 ER------KRPASMAV--------MEGDLVKKESFGVKLMDFQ-AHRRGGTLNRK--HIS 520
+R +RP S+A + L K +S GV++MD RRG + RK
Sbjct: 481 DRRQPEQARRPLSVATDNMMLEFYKKDGLRKIQSMGVRVMDTNWVARRGSSAGRKVSCAP 540
Query: 521 PAFQPPLPPTDGSTVVPAG-PEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKP 579
P+ QPP PP + + +P+ PE P S A + S PS G L+ GP + K
Sbjct: 541 PSMQPPAPPAELAAPLPSPLPEQPLDSPAAPALS-----PSGLG-LQPGPERTSTTKSKE 594
Query: 580 KDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHN-AAGPSPHTLRRAVKKPAP 638
P SA +PG + +G QP A G+ + P A SPHTLR+ KK AP
Sbjct: 595 LSPGSAQKGSPGSSQGTACAG-TQPGAQPGAQPGASPSPSQPPADQSPHTLRKVSKKLAP 653
Query: 639 APPKPGNPPPGHPGGQSSSGTSQ-HPPSLSPKPPTRSPSP----PTQHTGQPPGQ--PSA 691
PPK P G PG + Q P SLSP PP+ +PSP Q GQ P+A
Sbjct: 654 IPPK---VPFGQPGAMADQSAGQPSPVSLSPTPPS-TPSPYGLSYPQGYSLASGQLSPAA 709
Query: 692 PSQLSAPRRYSSSLS-------PIQAPNHPPPQPPTQATPLMHTKPNSQGPP 736
L++P ++S+LS P Q P PPPQPPT L + P S P
Sbjct: 710 APPLASPSVFTSTLSKSRPTPKPRQRPTLPPPQPPT--VNLSASSPQSTEAP 759
Score = 36.2 bits (82), Expect = 0.14
Identities = 36/115 (31%), Positives = 47/115 (40%), Gaps = 17/115 (14%)
Query: 711 PNHPPPQPPTQ-ATPLMHTKPNS--QGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLG 767
P+ PP PP + A PL P P P PS GL QP P +T T S
Sbjct: 541 PSMQPPAPPAELAAPLPSPLPEQPLDSPAAPALSPSGLGL-QPG--PERTSTTKSKE--- 594
Query: 768 KQNPSLPAPQTLAGGNPETAQ--PHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHS 820
+P + G+P ++Q AGT P +P +P PS PP H+
Sbjct: 595 ------LSPGSAQKGSPGSSQGTACAGTQPGAQPGAQPGASPSPSQPPADQSPHT 643
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 468 bits (1203), Expect = e-131
Identities = 304/775 (39%), Positives = 416/775 (53%), Gaps = 117/775 (15%)
Query: 1 MKKQFNRMKQLANQ-TVGRAEKT-EVLSEDLLQIERRLDTVRSICHHSHKRLVACFQGQH 58
MK+Q +RM+QLA ++GR +T E L EDLLQ+E+RL+ + H+ HKRL AC QGQ
Sbjct: 2 MKRQLHRMRQLAQTGSLGRTPETAEFLGEDLLQVEQRLEPAKRAAHNIHKRLQACLQGQS 61
Query: 59 GTDAERRHKKLPLTALAQNMQEASTQLE-DSLLGKMLETCGDAENQLALELSQHEVFVEK 117
G D ++R KKLPL AL+ M E+ +L+ DS +GK LE +NQLA L++ E+ +E+
Sbjct: 62 GADMDKRVKKLPLMALSTTMAESFKELDPDSSMGKALEMSCAIQNQLARILAEFEMTLER 121
Query: 118 EIVDPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGL-------- 169
+++ PL ++E E+P I K +K L +LV DW+++++R +QA K+SG++ QGL
Sbjct: 122 DVLQPLSRLSEEELPAILKHKKSLQKLVSDWNTLKSRLSQATKNSGSS-QGLGGSPGSHS 180
Query: 170 ----PSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRK 225
+K++TLKEE +E KVEQC+D+ AD+Y+F+ KE Y +F+ LLE QADYHR+
Sbjct: 181 HTTMANKVETLKEEEEELKRKVEQCRDEYLADLYHFVTKEDSYANYFIRLLEIQADYHRR 240
Query: 226 ALAVLEKTLPEMRAHQDKWAEKPA---------FGTPLEEHLKRSGREIALPIEACVMLL 276
+L+ L+ L E+R + + P+ +G L HL+ GREIALPIEACVM+L
Sbjct: 241 SLSSLDTALAELRENHGQADHSPSMTATHFPRVYGVSLATHLQELGREIALPIEACVMML 300
Query: 277 LETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLM 336
L GMKEEGLFR+ AGAS LK+LK + L+EF SDPHAVAGALKSYLRELPEPLM
Sbjct: 301 LSEGMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGALKSYLRELPEPLM 360
Query: 337 TFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTP 396
TF+LY++W + AS+++ +LQ L C +LPP+N N RYL+KFLA+LA+ +VNKMTP
Sbjct: 361 TFDLYDDWMRAASLKEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTP 420
Query: 397 SNIAIVLGPNLLW-ARNEGTLAEMAAA--TSVHVVAVIEPIIQHADWFFPEEVEFNVSEA 453
SNIAIVLGPNLLW EG A++ AA +S+ VV V+E +IQ AD FP ++ FNVS
Sbjct: 421 SNIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQSADTLFPGDINFNVSGL 480
Query: 454 FVPLTTPSSNHSFHTGNDSDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGT 513
F +T D+ S L + S AV
Sbjct: 481 FSAVTL----------QDTVSDRLASEELPSTAV-------------------------- 504
Query: 514 LNRKHISPAFQPPLPPTDGSTVVPA-GPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPG 572
PT +T PA P P P + A +++ T E P
Sbjct: 505 ---------------PTPATTPAPAPAPAPAPAPALASAATKERT--------ESEVPPR 541
Query: 573 DGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRA 632
SP + P A P +A +P P P P
Sbjct: 542 PASPKVTRSPPETAAPV-----EDMARRTKRP------------APARPTMPPPQVSGSR 584
Query: 633 VKKPAPAPPKPGNPPPGHPGG--QSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPS 690
PAP P PG+ PG P + G+S P++ P P P P + + + P PS
Sbjct: 585 SSPPAP-PLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPS 643
Query: 691 APSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNS-QGPPNPMALPSE 744
S A S SP+ N P Q A P + G P P A+P +
Sbjct: 644 PASPGPA------SPSPVSLSN--PAQVDLGAATAEGGAPEAISGVPTPPAIPPQ 690
Score = 71.6 bits (174), Expect = 3e-12
Identities = 73/260 (28%), Positives = 99/260 (38%), Gaps = 63/260 (24%)
Query: 566 EQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQ---NQPQAAAGSHQLSMGQPHNAA 622
E+ PS +P P A PAP + A+ + ++ S +++ P AA
Sbjct: 497 EELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAA 556
Query: 623 GPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHT 682
+ R K+PAPA +P PPP G +SS P+PP
Sbjct: 557 --PVEDMARRTKRPAPA--RPTMPPPQVSGSRSSP-----------------PAPPL--- 592
Query: 683 GQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALP 742
PPG S + + PRR S ++AP PPP PPT PP P
Sbjct: 593 --PPGSGSPGTPQALPRRLVGS--SLRAPTVPPPLPPT--------------PPQPARRQ 634
Query: 743 SEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLP--APQTLAGGNPETAQPHAGTLPRPRPV 800
S PS P +P P S P+ NP+ T GG PE V
Sbjct: 635 SRRSPASPS---PASPGPASPSPVSLSNPAQVDLGAATAEGGAPEAIS----------GV 681
Query: 801 PKPRNRPSVPPPPQPPGVHS 820
P P P++PP P+P + S
Sbjct: 682 PTP---PAIPPQPRPRSLAS 698
Score = 50.4 bits (119), Expect = 7e-06
Identities = 55/224 (24%), Positives = 71/224 (31%), Gaps = 56/224 (25%)
Query: 610 SHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPK 669
S +L+ + + A P+P T PAPAP P P + T P P
Sbjct: 491 SDRLASEELPSTAVPTPATT------PAPAPAPAPAPAPALASAATKERTESEVPP-RPA 543
Query: 670 PPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTK 729
P + SPP T P + ++ AP R + + PP PP
Sbjct: 544 SPKVTRSPP--ETAAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLP-------- 593
Query: 730 PNSQGPPNPMALPSE---HGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPET 786
P S P P ALP L P+ PP PTP
Sbjct: 594 PGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTP-------------------------- 627
Query: 787 AQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTA 830
P+P + R P P PG S SL+N A
Sbjct: 628 ----------PQPARRQSRRSPASPSPASPGPASPSPVSLSNPA 661
Score = 31.6 bits (70), Expect = 3.4
Identities = 23/77 (29%), Positives = 26/77 (33%), Gaps = 21/77 (27%)
Query: 784 PETAQPHAGTLPRPRPVPKPRNRPS-------------VPPPPQPPGVHSAGDSSLTNTA 830
P TA P T P P P P P P+ VPP P P V T +
Sbjct: 500 PSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKV--------TRSP 551
Query: 831 PTASKIVTDSNSRVSEP 847
P + V D R P
Sbjct: 552 PETAAPVEDMARRTKRP 568
>gi|23510413 sorting nexin 26 [Homo sapiens]
Length = 1126
Score = 124 bits (310), Expect = 5e-28
Identities = 158/668 (23%), Positives = 253/668 (37%), Gaps = 105/668 (15%)
Query: 224 RKALAVLEKTLPEMRAHQDKWAEKP-----AFGTPLEEHLKRSGREIALPIEACVMLLLE 278
R LA L +T R + + ++ FG L EHL SG+++ + C +
Sbjct: 282 RGKLAGLLRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQDVPQVLRCCSEFIEA 341
Query: 279 TGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDE-----FYSDPHAVAGALKSYLRELPE 333
G+ + G++R+ +S +++L+ D + + E F D H+V+ K Y RELP
Sbjct: 342 HGVVD-GIYRLSGVSSNIQRLRHEFD--SERIPELSGPAFLQDIHSVSSLCKLYFRELPN 398
Query: 334 PLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNK 393
PL+T+ LY ++++ SV ++++L + Q+LPP ++ YL++ LA++A+ S
Sbjct: 399 PLLTYQLYGKFSEAMSVPGEEERLVRVHDVIQQLPPPHYRTLEYLLRHLARMARHSANTS 458
Query: 394 MTPSNIAIVLGPNLLWARNEGTLAEMAAATSVHV---VAVIEPIIQHADWFFPEEVEFNV 450
M N+AIV PNLL + ++ AA V V+E ++ H D F +
Sbjct: 459 MHARNLAIVWAPNLLRSMELESVGMGGAAAFREVRVQSVVVEFLLTHVDVLFSD------ 512
Query: 451 SEAFVPLTTPSSNHSFHTGNDSDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRR 510
+F + +G RP S+A G ++ + R
Sbjct: 513 --------------TFTSAGLDPAGRCLLPRPKSLA---GSCPSTRLLTLEEAQARTQGR 555
Query: 511 GGTLNRKHISPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESS-SGGGTVPSSAGILEQGP 569
GT P PT + PA P + R E GG+ + L +GP
Sbjct: 556 LGT------------PTEPT--TPKAPASPAERRKGERGEKQRKPGGSSWKTFFALGRGP 601
Query: 570 S----------PGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPH 619
S G +PP+P V + + S Q A+G+ L G
Sbjct: 602 SVPRKKPLPWLGGTRAPPQPSGSRPDTVTLRSAKSEESLSSQ-----ASGAELLGAGGAP 656
Query: 620 NAAGPSPHTLRRAVKKPAPAP-PKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPP 678
+A P+P +P P G P Q + P SP PP
Sbjct: 657 ASATPTPALSPGRSLRPHLIPLLLRGAEAPLTDACQQEMCSKLRGAQGPLGPDMESPLPP 716
Query: 679 -----TQHTGQPPGQPSAPSQLS--APRRYSSSLSPIQAPNHPPPQPPTQATPLMHT--- 728
+ G PP P P++L A + ++ Q+ PP +P +
Sbjct: 717 PPLSLLRPGGAPPPPPKNPARLMALALAERAQQVAEQQSQQECGGTPPASQSPFHRSLSL 776
Query: 729 --------KPNSQGPPNPMALPSEHGLEQPSHTPPQ--------TPTPPSTPPLGKQNPS 772
S PPN +A P P + P Q + P T G + P+
Sbjct: 777 EVGGEPLGTSGSGPPPNSLAHPGAWVPGPPPYLPRQQSDGSLLRSQRPMGTSRRGLRGPA 836
Query: 773 LPAPQTLAGGN----PETAQPHAGTLPRPRPVP---KPRNRPSVPP--PPQPPGVHSAGD 823
+ Q AGG PE A ++P P P P R +PP PG++ G
Sbjct: 837 QVSAQLRAGGGGRDAPEAAAQSPCSVPSQVPTPGFFSPAPRECLPPFLGVPKPGLYPLGP 896
Query: 824 SSLTNTAP 831
S ++P
Sbjct: 897 PSFQPSSP 904
Score = 69.3 bits (168), Expect = 1e-11
Identities = 96/361 (26%), Positives = 124/361 (34%), Gaps = 71/361 (19%)
Query: 519 ISPAFQPPLPPTDGSTVVPAGPEPPPQSSRA------------------ESSSGGGTVPS 560
+ P + PLPP S + P G PPP + A GGT P+
Sbjct: 706 LGPDMESPLPPPPLSLLRPGGAPPPPPKNPARLMALALAERAQQVAEQQSQQECGGTPPA 765
Query: 561 SAG------ILEQGPSP----GDGSPPKPKDPVSAAVPAP-------GRNNSQIASGQNQ 603
S LE G P G G PP A VP P + S + S +
Sbjct: 766 SQSPFHRSLSLEVGGEPLGTSGSGPPPNSLAHPGAWVPGPPPYLPRQQSDGSLLRSQRPM 825
Query: 604 PQAAAG-------SHQLSMG----QPHNAAGPSPHTLRRAVKKP---APAP--------- 640
+ G S QL G AA SP ++ V P +PAP
Sbjct: 826 GTSRRGLRGPAQVSAQLRAGGGGRDAPEAAAQSPCSVPSQVPTPGFFSPAPRECLPPFLG 885
Query: 641 -PKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPR 699
PKPG P G P Q SS SL P P G G P S P
Sbjct: 886 VPKPGLYPLGPPSFQPSSPAPVWRSSLGPPAPLDRGENLYYEIGASEGSP-----YSGPT 940
Query: 700 RYSSSLSPIQAPNHPPPQPPTQATPLMHTKPN--SQGPPNPMALPSEH-GLEQPSHTPPQ 756
R S + +P +H P+ PP P P +H G P H P +
Sbjct: 941 RSWSPFRSMPPDRLNASYGMLGQSPPLHRSPDFLLSYPPAPSCFPPDHLGYSAPQH-PAR 999
Query: 757 TPTPPSTPPLG-KQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQP 815
PTPP + P P+P + + +P A P + + P P PVP+ + P P+
Sbjct: 1000 RPTPPEPLYVNLALGPRGPSPASSSSSSP-PAHPRSRSDPGP-PVPRLPQKQRAPWGPRT 1057
Query: 816 P 816
P
Sbjct: 1058 P 1058
Score = 33.1 bits (74), Expect = 1.2
Identities = 57/225 (25%), Positives = 76/225 (33%), Gaps = 61/225 (27%)
Query: 521 PAFQPPLP-PTDGSTVVPAGP--------------EPPPQSSRAESSSGGGTVP-----S 560
P+FQP P P S++ P P E P S S S ++P +
Sbjct: 897 PSFQPSSPAPVWRSSLGPPAPLDRGENLYYEIGASEGSPYSGPTRSWSPFRSMPPDRLNA 956
Query: 561 SAGILEQGP----SPGD--GSPPKPK----DPVSAAVPA-PGRNNS-------QIASGQN 602
S G+L Q P SP PP P D + + P P R + +A G
Sbjct: 957 SYGMLGQSPPLHRSPDFLLSYPPAPSCFPPDHLGYSAPQHPARRPTPPEPLYVNLALGPR 1016
Query: 603 QPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAP-------------APPKP-----G 644
P A+ S P + + P P R K+ AP PP+P
Sbjct: 1017 GPSPASSSSSSPPAHPRSRSDPGPPVPRLPQKQRAPWGPRTPHRVPGPWGPPEPLLLYRA 1076
Query: 645 NPPPGHPGGQSSSGT-----SQHPPSLSPKPPTRSPSPPTQHTGQ 684
PP GG+ G+ Q P PP +PS GQ
Sbjct: 1077 APPAYGRGGELHRGSLYRNGGQRGEGAGPPPPYPTPSWSLHSEGQ 1121
>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
sapiens]
Length = 655
Score = 117 bits (294), Expect = 4e-26
Identities = 72/207 (34%), Positives = 118/207 (57%), Gaps = 8/207 (3%)
Query: 247 KPAFGTPLEEHL---KRSGREIA-LPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAA 302
K FG LE+ + KR G +A + +E CV + + G+KEEGLFR+ A+ +K+L+ A
Sbjct: 37 KGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDA 96
Query: 303 LDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASV--QDQDKKLQDL 360
DC + +D H VA LK YLRELPEP++ + YE++ A + ++++ +++L
Sbjct: 97 FDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKEL 156
Query: 361 WRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMA 420
+ + LP N+ +Y+ +FL ++ S VNKM+ N+A V GPN+L + E L M
Sbjct: 157 AKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIME 216
Query: 421 AATSVHVVAVIEPIIQHADWFFPEEVE 447
+V V ++ +I D FP++ E
Sbjct: 217 G--TVVVQQLMSVMISKHDCLFPKDAE 241
>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
sapiens]
Length = 653
Score = 117 bits (292), Expect = 6e-26
Identities = 71/204 (34%), Positives = 117/204 (57%), Gaps = 8/204 (3%)
Query: 250 FGTPLEEHL---KRSGREIA-LPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDC 305
FG LE+ + KR G +A + +E CV + + G+KEEGLFR+ A+ +K+L+ A DC
Sbjct: 38 FGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDC 97
Query: 306 STSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASV--QDQDKKLQDLWRT 363
+ +D H VA LK YLRELPEP++ + YE++ A + ++++ +++L +
Sbjct: 98 GEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQ 157
Query: 364 CQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAAT 423
+ LP N+ +Y+ +FL ++ S VNKM+ N+A V GPN+L + E L M
Sbjct: 158 VKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEG-- 215
Query: 424 SVHVVAVIEPIIQHADWFFPEEVE 447
+V V ++ +I D FP++ E
Sbjct: 216 TVVVQQLMSVMISKHDCLFPKDAE 239
>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
sapiens]
Length = 748
Score = 117 bits (292), Expect = 6e-26
Identities = 71/204 (34%), Positives = 117/204 (57%), Gaps = 8/204 (3%)
Query: 250 FGTPLEEHL---KRSGREIA-LPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDC 305
FG LE+ + KR G +A + +E CV + + G+KEEGLFR+ A+ +K+L+ A DC
Sbjct: 133 FGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDC 192
Query: 306 STSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASV--QDQDKKLQDLWRT 363
+ +D H VA LK YLRELPEP++ + YE++ A + ++++ +++L +
Sbjct: 193 GEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQ 252
Query: 364 CQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAAT 423
+ LP N+ +Y+ +FL ++ S VNKM+ N+A V GPN+L + E L M
Sbjct: 253 VKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEG-- 310
Query: 424 SVHVVAVIEPIIQHADWFFPEEVE 447
+V V ++ +I D FP++ E
Sbjct: 311 TVVVQQLMSVMISKHDCLFPKDAE 334
>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
Length = 698
Score = 114 bits (285), Expect = 4e-25
Identities = 73/199 (36%), Positives = 113/199 (56%), Gaps = 9/199 (4%)
Query: 250 FGTPLEE---HLKRSGREIA-LPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDC 305
FG LEE H ++ G +A L +E CV + E G+ EEGLFR+ A+ ++ L+ + DC
Sbjct: 153 FGQRLEETVHHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDC 212
Query: 306 STSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASV--QDQDKKLQDLWRT 363
L + +D H VA LK YLRELPEP++ F YE++ A + +D+ + +L +
Sbjct: 213 GEKPLFDSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQ 272
Query: 364 CQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAAT 423
LP N+ RY+ KFL ++ S+VNKM+ N+A V GPN+L + E + M +
Sbjct: 273 VSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTS 332
Query: 424 SV-HVVAVIEPIIQHADWF 441
V H++ V+ I +H+ F
Sbjct: 333 LVQHLMTVL--IRKHSQLF 349
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 109 bits (272), Expect = 1e-23
Identities = 97/340 (28%), Positives = 119/340 (35%), Gaps = 58/340 (17%)
Query: 510 RGGTLNRKHISPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTV--PSSAGILEQ 567
+GG + SP +P PP G P GP PPP + GG P G Q
Sbjct: 42 QGGNKPQGPPSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQGGNKPQGPPPPG-KPQ 99
Query: 568 GPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPH 627
GP P P+ P PG+ G NQPQ GP P
Sbjct: 100 GPPPQGDKSRSPRSP-------PGKPQGPPPQGGNQPQ-----------------GPPPP 135
Query: 628 TLRRAVKKPAPAPPKPGN-----PPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHT 682
KP PP+ GN PPPG P G G ++ S SP P + PP Q
Sbjct: 136 P-----GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP--PGKPQGPPPQGG 188
Query: 683 GQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALP 742
QP G P P + P + P P PP Q + +++ PP P
Sbjct: 189 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD---NKSQSARSPPGKPQGP 245
Query: 743 SEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPR---- 798
G QP PP P PP G P P P G P+ P G+ R
Sbjct: 246 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP----GKPQGPPPQGGSKSRSSRSPP 301
Query: 799 -----PVPKPRNRPSVPPPP--QPPGVHSAGDSSLTNTAP 831
P P+ N+P PPPP +P G G + P
Sbjct: 302 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 341
Score = 108 bits (270), Expect = 2e-23
Identities = 96/320 (30%), Positives = 117/320 (36%), Gaps = 59/320 (18%)
Query: 512 GTLNRKHISPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSP 571
G +R SP +P PP G P GP PPP + GG QGP P
Sbjct: 105 GDKSRSPRSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQGGNK--------PQGPPP 155
Query: 572 G---DGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHT 628
G PP+ + ++ PG+ G NQPQ GP P
Sbjct: 156 PGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQ-----------------GPPPPP 198
Query: 629 LRRAVKKPAPAPPKPGN-----PPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTG 683
KP PP+ GN PPPG P G G ++ + SP P + PP Q
Sbjct: 199 -----GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP--PGKPQGPPPQGGN 251
Query: 684 QPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKP-NSQGPPNPMALP 742
QP G P P + P + Q P PPP P P +K +S+ PP P
Sbjct: 252 QPQGPPPPPGKPQGPPPQGGNKP--QGP--PPPGKPQGPPPQGGSKSRSSRSPPGKPQGP 307
Query: 743 SEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRP--RPV 800
G QP PP P PP G P P P G P+ P G+ R P
Sbjct: 308 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP----GKPQGPPPQGGSKSRSARSPP 363
Query: 801 PKPR-------NRPSVPPPP 813
KP+ N P PPPP
Sbjct: 364 GKPQGPPQQEGNNPQGPPPP 383
Score = 94.4 bits (233), Expect = 4e-19
Identities = 90/288 (31%), Positives = 107/288 (37%), Gaps = 54/288 (18%)
Query: 510 RGGTLNRKHISPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGP 569
+G +R SP +P PP G P GP PPP + GG QGP
Sbjct: 165 QGDNKSRSSRSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQGGNK--------PQGP 215
Query: 570 SPG---DGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSP 626
P G PP+ + +A PG+ G NQPQ GP P
Sbjct: 216 PPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQ-----------------GPPP 258
Query: 627 HTLRRAVKKPAPAPPKPGN-----PPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQH 681
KP PP+ GN PPPG P G G S+ S SP P + PP Q
Sbjct: 259 PP-----GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP--PGKPQGPPPQG 311
Query: 682 TGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNS-QGPPN-PM 739
QP G P P + P + Q P PPP P P +K S + PP P
Sbjct: 312 GNQPQGPPPPPGKPQGPPPQGGNKP--QGP--PPPGKPQGPPPQGGSKSRSARSPPGKPQ 367
Query: 740 ALPSEHGLEQPSHTPPQ--TPTPPSTPPLGK-QNPSLPAPQTLAGGNP 784
P + G PP P P PP G+ Q P P PQ GG P
Sbjct: 368 GPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP-PQ---GGRP 411
Score = 90.5 bits (223), Expect = 6e-18
Identities = 78/282 (27%), Positives = 93/282 (32%), Gaps = 47/282 (16%)
Query: 562 AGILEQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNA 621
AG + P G P P P PG+ G NQPQ
Sbjct: 33 AGNPQGAPPQGGNKPQGPPSP-------PGKPQGPPPQGGNQPQ---------------- 69
Query: 622 AGPSPHTLRRAVKKPAPAPPKPGN-----PPPGHPGGQSSSGTSQHPPSLSPKPPTRSPS 676
GP P KP PP+ GN PPPG P G G P PP +
Sbjct: 70 -GPPP-----PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR---SPPGKPQG 120
Query: 677 PPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPP 736
PP Q QP G P P + P + P P PP Q + +S+ PP
Sbjct: 121 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD---NKSRSSRSPP 177
Query: 737 NPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPR 796
P G QP PP P PP G P P P G P + +
Sbjct: 178 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARS 237
Query: 797 P-----RPVPKPRNRPSVPPPP--QPPGVHSAGDSSLTNTAP 831
P P P+ N+P PPPP +P G G + P
Sbjct: 238 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 279
>gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]
Length = 2087
Score = 108 bits (269), Expect = 3e-23
Identities = 65/221 (29%), Positives = 112/221 (50%), Gaps = 11/221 (4%)
Query: 250 FGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSH 309
FG L EHL SG E+ +++C + G+ + G++R+ AS +++L+ D + H
Sbjct: 370 FGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRLSGVASNIQRLRHEFD--SEH 426
Query: 310 LDEFYSDP-----HAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTC 364
+ + +P H+V K Y RELP PL+T+ LYE+++ S +++L +
Sbjct: 427 VPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVI 486
Query: 365 QKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWAR--NEGTLAEMAAA 422
Q+LPP ++ +L++ L+ LA + M N+AIV PNLL ++ + AA
Sbjct: 487 QQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAF 546
Query: 423 TSVHVVA-VIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSS 462
V + + V+E I+ H D F + + E L+ P S
Sbjct: 547 MEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKS 587
Score = 41.2 bits (95), Expect = 0.004
Identities = 82/331 (24%), Positives = 113/331 (34%), Gaps = 53/331 (16%)
Query: 525 PPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVS 584
PP PP + + ++ Q + +S GT S AG G D + +D +S
Sbjct: 1032 PPPPPKNVARMLALALAESAQQASTQSLKRPGT--SQAGYTNYG----DIAVATTEDNLS 1085
Query: 585 AAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPG 644
++ A + + Q A L P N P P T P
Sbjct: 1086 SSYSAVALDKAYF-----QTDRPAEQFHLQNNAPGNCDHPLPETTATG------DPTHSN 1134
Query: 645 NPPPGHPGGQSS-SGTSQHPPSLSPKPP-TRSPSPPTQ------HTGQPP---GQPSAPS 693
G Q +G H LS P R S P H P G+ S P+
Sbjct: 1135 TTESGEQHHQVDLTGNQPHQAYLSGDPEKARITSVPLDSEKSDDHVSFPEDQSGKNSMPT 1194
Query: 694 ------QLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGL 747
S PR YS + PP L H + P P LPS+ +
Sbjct: 1195 VSFLDQDQSPPRFYSG--------DQPPSYLGASVDKLHHPLEFADKSPTPPNLPSDK-I 1245
Query: 748 EQPSHTPPQ-----TPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRP----R 798
PS +P + T T +T P Q + A +A P TA A TL R R
Sbjct: 1246 YPPSGSPEENTSTATMTYMTTTPATAQMSTKEASWDVAE-QPTTADFAAATLQRTHRTNR 1304
Query: 799 PVPKPRNRPSVPPPPQPPGVHSAGDSSLTNT 829
P+P P ++ S PP V +A + L N+
Sbjct: 1305 PLPPPPSQRSAEQPPVVGQVQAATNIGLNNS 1335
Score = 33.9 bits (76), Expect = 0.68
Identities = 57/262 (21%), Positives = 87/262 (33%), Gaps = 43/262 (16%)
Query: 567 QGPSPGDGSPPKPK-----DPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQ---- 617
Q +PG+ P P+ DP + G + Q+ NQP A S +
Sbjct: 1110 QNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSGDPEKARITSV 1169
Query: 618 -------------PHNAAGP-SPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHP 663
P + +G S T+ + +P G+ PP + G +S HP
Sbjct: 1170 PLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLG--ASVDKLHHP 1227
Query: 664 PSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQAT 723
+ K PT P+ P+ P G P + +A Y ++ T AT
Sbjct: 1228 LEFADKSPT-PPNLPSDKIYPPSGSPEENTS-TATMTYMTT---------------TPAT 1270
Query: 724 PLMHTKPNSQG-PPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGG 782
M TK S P Q +H + PP + +Q P + Q
Sbjct: 1271 AQMSTKEASWDVAEQPTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNI 1330
Query: 783 NPETAQPHAGTLPRPRPVPKPR 804
+ G +P P P+PR
Sbjct: 1331 GLNNSHKVQGVVPVPERPPEPR 1352
>gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]
Length = 1738
Score = 108 bits (269), Expect = 3e-23
Identities = 65/221 (29%), Positives = 112/221 (50%), Gaps = 11/221 (4%)
Query: 250 FGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSH 309
FG L EHL SG E+ +++C + G+ + G++R+ AS +++L+ D + H
Sbjct: 21 FGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRLSGVASNIQRLRHEFD--SEH 77
Query: 310 LDEFYSDP-----HAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTC 364
+ + +P H+V K Y RELP PL+T+ LYE+++ S +++L +
Sbjct: 78 VPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVI 137
Query: 365 QKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWAR--NEGTLAEMAAA 422
Q+LPP ++ +L++ L+ LA + M N+AIV PNLL ++ + AA
Sbjct: 138 QQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAF 197
Query: 423 TSVHVVA-VIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSS 462
V + + V+E I+ H D F + + E L+ P S
Sbjct: 198 MEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKS 238
Score = 41.2 bits (95), Expect = 0.004
Identities = 82/331 (24%), Positives = 113/331 (34%), Gaps = 53/331 (16%)
Query: 525 PPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVS 584
PP PP + + ++ Q + +S GT S AG G D + +D +S
Sbjct: 683 PPPPPKNVARMLALALAESAQQASTQSLKRPGT--SQAGYTNYG----DIAVATTEDNLS 736
Query: 585 AAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPG 644
++ A + + Q A L P N P P T P
Sbjct: 737 SSYSAVALDKAYF-----QTDRPAEQFHLQNNAPGNCDHPLPETTATG------DPTHSN 785
Query: 645 NPPPGHPGGQSS-SGTSQHPPSLSPKPP-TRSPSPPTQ------HTGQPP---GQPSAPS 693
G Q +G H LS P R S P H P G+ S P+
Sbjct: 786 TTESGEQHHQVDLTGNQPHQAYLSGDPEKARITSVPLDSEKSDDHVSFPEDQSGKNSMPT 845
Query: 694 ------QLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGL 747
S PR YS + PP L H + P P LPS+ +
Sbjct: 846 VSFLDQDQSPPRFYSG--------DQPPSYLGASVDKLHHPLEFADKSPTPPNLPSDK-I 896
Query: 748 EQPSHTPPQ-----TPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRP----R 798
PS +P + T T +T P Q + A +A P TA A TL R R
Sbjct: 897 YPPSGSPEENTSTATMTYMTTTPATAQMSTKEASWDVAE-QPTTADFAAATLQRTHRTNR 955
Query: 799 PVPKPRNRPSVPPPPQPPGVHSAGDSSLTNT 829
P+P P ++ S PP V +A + L N+
Sbjct: 956 PLPPPPSQRSAEQPPVVGQVQAATNIGLNNS 986
Score = 33.9 bits (76), Expect = 0.68
Identities = 57/262 (21%), Positives = 87/262 (33%), Gaps = 43/262 (16%)
Query: 567 QGPSPGDGSPPKPK-----DPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQ---- 617
Q +PG+ P P+ DP + G + Q+ NQP A S +
Sbjct: 761 QNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSGDPEKARITSV 820
Query: 618 -------------PHNAAGP-SPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHP 663
P + +G S T+ + +P G+ PP + G +S HP
Sbjct: 821 PLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLG--ASVDKLHHP 878
Query: 664 PSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQAT 723
+ K PT P+ P+ P G P + +A Y ++ T AT
Sbjct: 879 LEFADKSPT-PPNLPSDKIYPPSGSPEENTS-TATMTYMTT---------------TPAT 921
Query: 724 PLMHTKPNSQG-PPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGG 782
M TK S P Q +H + PP + +Q P + Q
Sbjct: 922 AQMSTKEASWDVAEQPTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNI 981
Query: 783 NPETAQPHAGTLPRPRPVPKPR 804
+ G +P P P+PR
Sbjct: 982 GLNNSHKVQGVVPVPERPPEPR 1003
>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
Length = 1397
Score = 107 bits (268), Expect = 4e-23
Identities = 137/617 (22%), Positives = 236/617 (38%), Gaps = 101/617 (16%)
Query: 241 QDKWAEKPAFGTPLEE-HLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKL 299
++K A AFG LEE + + L + AC ++ G++ G++R+ + + L
Sbjct: 800 KNKKAAPRAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSL 859
Query: 300 KAALDCSTSHL---DEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKK 356
+ L+ + DE + D + ++ LKS+ R+LPEPL T + Y ++ + ++D ++
Sbjct: 860 QEQLNRGPGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARER 919
Query: 357 LQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTL 416
++ L + + LP + ++L+ L +A S+ NKM P N+A+V GP L+ +E +
Sbjct: 920 MRTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLV-RTSEDNM 978
Query: 417 AEMAAATSVHVVAVIEPIIQHADWFFPEE-------------------VEF---NVSEAF 454
+M ++E +IQH+DWFF +E +E+ N+
Sbjct: 979 TDMVTHMPDR-YKIVETLIQHSDWFFSDEEDKGERTPVGDKEPQAVPNIEYLLPNIGRT- 1036
Query: 455 VPLTTPSSNHSFHTGNDSDSGTLERKRPASMAVMEGDLV---------KKESFGVKL--- 502
VP P S+ + + S +K P + ++ + ++E+ G+
Sbjct: 1037 VPPGDPGSDSTTCSSAKSKGSWAPKKEPYAREMLAISFISAVNRKRKKRREARGLGSSTD 1096
Query: 503 --MDFQAHRRGGTLNRKHISPAFQPPL-----PPTDGSTVVPAGPEPPPQSSRAESSSGG 555
+ +AH+ G Q PL P G PA PE P + SG
Sbjct: 1097 DDSEQEAHKPGAGATAPGTQERPQGPLPGAVAPEAPGRLSPPAAPEERPAADTRSIVSGY 1156
Query: 556 GTVPS-----SAGILEQGPSPGDGSPPK-------PKDPVSAAVPAPG---RNNSQIASG 600
T+ + +G + GD + + D AA PG +S
Sbjct: 1157 STLSTMDRSVCSGASGRRAGAGDEADDERSELSHVETDTEGAAGAGPGGRLTRRPSFSSH 1216
Query: 601 QNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTS 660
P +L+ G+P + P P+ PPG SSS S
Sbjct: 1217 HLMPCDTLARRRLARGRPDG----------EGAGRGGPRAPE----PPG--SASSSSQES 1260
Query: 661 QHPPSLS-PKPPTRSPSPPTQHTG----------QPPGQPSAPSQLSAPRRYSSSL-SPI 708
PP+ + P+R + + G + P P + S+ RR++ + SP+
Sbjct: 1261 LRPPAAALASRPSRMEALRLRLRGTADDMLAVRLRRPLSPETRRRRSSWRRHTVVVQSPL 1320
Query: 709 QAPNHPPPQ------PPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPS 762
N + PP A H+ G ++ PS Q P P
Sbjct: 1321 TDLNFNEWKELGGGGPPEPAGARAHSDNKDSG----LSSLESTKARAPSSAASQPPAPGD 1376
Query: 763 TPPLGKQNPSLPAPQTL 779
T L Q P A L
Sbjct: 1377 TGSLQSQPPRRSAASRL 1393
Score = 31.2 bits (69), Expect = 4.4
Identities = 27/121 (22%), Positives = 44/121 (36%), Gaps = 7/121 (5%)
Query: 685 PPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSE 744
PPG P + S + + S +P + P + ++ K + + ++
Sbjct: 1038 PPGDPGSDSTTCSSAKSKGSWAPKKEP-YAREMLAISFISAVNRKRKKRREARGLGSSTD 1096
Query: 745 HGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPR 804
EQ +H P T P T ++ P P P +A P P A P RP R
Sbjct: 1097 DDSEQEAHKPGAGATAPGT----QERPQGPLPGAVAPEAPGRLSPPAA--PEERPAADTR 1150
Query: 805 N 805
+
Sbjct: 1151 S 1151
>gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo
sapiens]
Length = 890
Score = 107 bits (266), Expect = 6e-23
Identities = 94/383 (24%), Positives = 171/383 (44%), Gaps = 36/383 (9%)
Query: 245 AEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALD 304
A++ FG L+EHL+ SG+E+ +++C + E G+ + G++R+ +S ++KL+ +
Sbjct: 13 AKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVD-GIYRLSGVSSNIQKLRQEFE 71
Query: 305 CSTS---HLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLW 361
D + D H V+ K+Y RELP+PL+T+ LY+++ + VQ + ++L +
Sbjct: 72 SERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGVQLEPERLVKIL 131
Query: 362 RTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARN------EGT 415
++LP N+ +L++ L +A S M N+AIV PNLL +++ GT
Sbjct: 132 EVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRSKDIEASGFNGT 191
Query: 416 LAEMAAATSVHVVAVIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSSNHSFHTGNDSDSG 475
A M V+E I+ H D F +S V S + +G+ D
Sbjct: 192 AAFMEVRVQ---SIVVEFILTHVDQLFGGAA---LSGGEVESGWRSLPGTRASGSPED-- 243
Query: 476 TLERKRPASM--AVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGS 533
+ R P + + GD + +++ H+R G+L + F +
Sbjct: 244 LMPRPLPYHLPSILQAGDGPPQMRPYHTIIEIAEHKRKGSLKVRKWRSIFNLGRSGHETK 303
Query: 534 TVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPG-- 591
+P G E R + S+ G P+ + S G+ +P+ V + P P
Sbjct: 304 RKLPRGAE-----DREDKSNKGTLRPAKS---MDSLSAAAGASDEPEGLVGPSSPRPSPL 355
Query: 592 ------RNNSQIASGQNQPQAAA 608
++ + A G+ +P+A A
Sbjct: 356 LPESLENDSIEAAEGEQEPEAEA 378
>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
sapiens]
Length = 1101
Score = 107 bits (266), Expect = 6e-23
Identities = 94/383 (24%), Positives = 171/383 (44%), Gaps = 36/383 (9%)
Query: 245 AEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALD 304
A++ FG L+EHL+ SG+E+ +++C + E G+ + G++R+ +S ++KL+ +
Sbjct: 13 AKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVD-GIYRLSGVSSNIQKLRQEFE 71
Query: 305 CSTS---HLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLW 361
D + D H V+ K+Y RELP+PL+T+ LY+++ + VQ + ++L +
Sbjct: 72 SERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGVQLEPERLVKIL 131
Query: 362 RTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARN------EGT 415
++LP N+ +L++ L +A S M N+AIV PNLL +++ GT
Sbjct: 132 EVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRSKDIEASGFNGT 191
Query: 416 LAEMAAATSVHVVAVIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSSNHSFHTGNDSDSG 475
A M V+E I+ H D F +S V S + +G+ D
Sbjct: 192 AAFMEVRVQ---SIVVEFILTHVDQLFGGAA---LSGGEVESGWRSLPGTRASGSPED-- 243
Query: 476 TLERKRPASM--AVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGS 533
+ R P + + GD + +++ H+R G+L + F +
Sbjct: 244 LMPRPLPYHLPSILQAGDGPPQMRPYHTIIEIAEHKRKGSLKVRKWRSIFNLGRSGHETK 303
Query: 534 TVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPG-- 591
+P G E R + S+ G P+ + S G+ +P+ V + P P
Sbjct: 304 RKLPRGAE-----DREDKSNKGTLRPAKS---MDSLSAAAGASDEPEGLVGPSSPRPSPL 355
Query: 592 ------RNNSQIASGQNQPQAAA 608
++ + A G+ +P+A A
Sbjct: 356 LPESLENDSIEAAEGEQEPEAEA 378
>gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]
Length = 946
Score = 105 bits (261), Expect = 2e-22
Identities = 140/620 (22%), Positives = 239/620 (38%), Gaps = 82/620 (13%)
Query: 112 EVFVEKEIVDPLYGIAEVEIPNIQKQRKQLARLVLDWDSV--------RARWNQAHKSSG 163
E+ VE E+ D + +P Q + +L R ++ + V +A G
Sbjct: 347 EICVEMELRDEI-------LPRAQNIQSRLDRQTIETEEVNKTLKATLQALLEVVASDDG 399
Query: 164 T---NFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEY--GKFFVTLLEA 218
+FQ PS D + + + Q ++ K EY G+ + L+A
Sbjct: 400 DVLDSFQTSPSTESLKSTSSDPGSRQAGRRRGQQQETETFYLTKLQEYLSGRSILAKLQA 459
Query: 219 QADYHRKALAVLEKTLPEM-------RAHQDKWAEKPA-------FGTPLEEHLKRSGRE 264
+ + ++AL +K E+ R Q +P+ FG +E+ ++ SG+
Sbjct: 460 KHEKLQEALQRGDKEEQEVSWTQYTQRKFQKSRQPRPSSQYNQRLFGGDMEKFIQSSGQP 519
Query: 265 IALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYS--DPHAVAG 322
+ L +E+C+ + G++ EG+FR+ ++ +++ A + L E + D +VAG
Sbjct: 520 VPLVVESCIRFINLNGLQHEGIFRVSGAQLRVSEIRDAFERGEDPLVEGCTAHDLDSVAG 579
Query: 323 ALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFL 382
LK Y R L PL +L+ E + ++ ++++ + R +LP V RYL FL
Sbjct: 580 VLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFL 639
Query: 383 AKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATSVHVVAVIEPIIQHADWFF 442
LAQ SD N M P N+A+ GP LL + A V +++ +I D F
Sbjct: 640 NHLAQYSDENMMDPYNLAVCFGPTLL----PVPAGQDPVALQGRVNQLVQTLIVQPDRVF 695
Query: 443 PEEVEFNVSEAFVPLTTPSSN-------HSFHTGNDSDSGTLERKRPASMAVMEG--DLV 493
P + PS++ S N+ + LE + PA +EG + V
Sbjct: 696 PPLTSLPGPVYEKCMAPPSASCLGDAQLESLGADNEPE---LEAEMPAQEDDLEGVVEAV 752
Query: 494 KKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGS--------TVVPAGPEPPPQ 545
++ + + RRG L R H + +G +PAG E
Sbjct: 753 ACFAYTGRTAQELSFRRGDVL-RLHERASSDWWRGEHNGMRGLIPHKYITLPAGTEKQVV 811
Query: 546 SSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVS----AAVPAPGRNNSQIASGQ 601
+ +++ G+ P E P + P+ P VPA + ++
Sbjct: 812 GAGLQTAGESGSSPEGLLASELVHRPEPCTSPEAMGPSGHRRRCLVPASPEQHVEVDKAV 871
Query: 602 NQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPG--------- 652
Q + L GP+ T P+P P P PP G
Sbjct: 872 AQNMDSVFKELLGKTSVRQGLGPASTT------SPSPGPRSPKAPPSSRLGRNKGFSRGP 925
Query: 653 GQSSSGTSQHPPSL--SPKP 670
G +S ++ HP L +PKP
Sbjct: 926 GAPASPSASHPQGLDTTPKP 945
>gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapiens]
Length = 1085
Score = 103 bits (256), Expect = 9e-22
Identities = 131/595 (22%), Positives = 223/595 (37%), Gaps = 48/595 (8%)
Query: 250 FGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSH 309
F LE +K SG+ I L +E+C+ + G++ +G+FR+ ++ +K + + +
Sbjct: 504 FNGDLETFVKDSGQVIPLIVESCIRFINLYGLQHQGIFRVSGSQVEVNDIKNSFERGENP 563
Query: 310 L--DEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKL 367
L D+ D ++VAG LK Y R L PL + + + + ++ + + L
Sbjct: 564 LADDQSNHDINSVAGVLKLYFRGLENPLFPKERFNDLISCIRIDNLYERALHIRKLLLTL 623
Query: 368 PPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATSVHV 427
P + RYL FL L+Q SD N M P N+AI GP L+ + + HV
Sbjct: 624 PRSVLIVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMPVPE----IQDQVSCQAHV 679
Query: 428 VAVIEPIIQHADWFFPEEVEFN--VSEAFVP----LTTPSSNHSFHTGNDSDSGTLERKR 481
+I+ II H + FP+ E + V E + +P S H D D+GT
Sbjct: 680 NEIIKTIIIHHETIFPDAKELDGPVYEKCMAGDDYCDSPYSEHGTLEEVDQDAGTEPHTS 739
Query: 482 PASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPA--FQPPLPPTDGST----- 534
+E + K + G + + ++G +L H + ++ DG
Sbjct: 740 EDECEPIEA-IAKFDYVGRSAREL-SFKKGASLLLYHRASEDWWEGRHNGIDGLVPHQYI 797
Query: 535 VVPAGPEP--PPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPK--PKDPVSAAVPAP 590
VV + S +A+S + G V + SP D P + P P
Sbjct: 798 VVQDMDDTFSDTLSQKADSEASSGPVTEDKSSSKDMNSPTDRHPDGYLARQRKRGEPPPP 857
Query: 591 GRNNSQIASGQN--QPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPP 648
R + + G P A + + +G P A+ P R + +P +
Sbjct: 858 VRRPGRTSDGHCPLHPPHALSNSSVDLGSPSLASHPRGLLQNRGLNNDSPERRR------ 911
Query: 649 GHPGGQSSSGTSQHPPSLS-PKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYS----- 702
PG S + S+H PP R + Q+TG +P P ++ +
Sbjct: 912 -RPGHGSLTNISRHDSLKKIDSPPIRRSTSSGQYTGFNDHKPLDPETIAQDIEETMNTAL 970
Query: 703 SSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPS 762
+ L ++ + P L K + + +L H + S P + S
Sbjct: 971 NELRELERQSTAKHAPDVVLDTLEQVKNSPTPATSTESLSPLHNVALRSSEPQIRRSTSS 1030
Query: 763 TPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPG 817
+ + AP+ P RP+P P+ P++ P P P G
Sbjct: 1031 SSDTMSTFKPMVAPRMGVQLKPPAL--------RPKPAVLPKTNPTIGPAPPPQG 1077
>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
Length = 1444
Score = 102 bits (254), Expect = 2e-21
Identities = 66/200 (33%), Positives = 105/200 (52%), Gaps = 7/200 (3%)
Query: 249 AFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAAL---DC 305
AFG L E+L+ SG+++ +++C + ET +G++R+ S +++L+ C
Sbjct: 18 AFGCDLTEYLESSGQDVPYVLKSCAEFI-ETHGIVDGIYRLSGVTSNIQRLRQEFGSDQC 76
Query: 306 STSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQ 365
+ + D H V K Y RELP PL+T+ LYE++T+ S ++ +L + Q
Sbjct: 77 PDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLARIQNVIQ 136
Query: 366 KLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARN-EGTLAE-MAAAT 423
+LPP ++ YLI+ LA +A S M N+A+V PNLL ++ E T AA
Sbjct: 137 ELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKEIEATGCNGDAAFL 196
Query: 424 SVHV-VAVIEPIIQHADWFF 442
+V V VIE I+ H D F
Sbjct: 197 AVRVQQVVIEFILNHVDQIF 216
Score = 34.3 bits (77), Expect = 0.52
Identities = 25/104 (24%), Positives = 43/104 (41%), Gaps = 9/104 (8%)
Query: 651 PGGQSSSGTSQHPPSLSPKP-----PTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSL 705
P QS+ G S P+P P + P + P A ++ P +L
Sbjct: 722 PANQSTQGASTAASREKPEPEQGLHPDLASLAPLEIVPFEKASPQATVEVGGP----GNL 777
Query: 706 SPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQ 749
SP P PPP P ++TP++ +K + + L ++ ++Q
Sbjct: 778 SPPLPPAPPPPTPLEESTPVLLSKGGPEREDSSRKLRTDLYIDQ 821
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 101 bits (252), Expect = 3e-21
Identities = 88/300 (29%), Positives = 101/300 (33%), Gaps = 49/300 (16%)
Query: 526 PLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTV--PSSAGILEQGPSPGDGSPPKPKDPV 583
P P+ P GP PPP + GG P G QGP P P+ P
Sbjct: 36 PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPG-KPQGPPPQGDKSRSPRSP- 93
Query: 584 SAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKP 643
PG+ G NQPQ GP P KP PP+
Sbjct: 94 ------PGKPQGPPPQGGNQPQ-----------------GPPPPP-----GKPQGPPPQG 125
Query: 644 GN-----PPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAP 698
GN PPPG P G G P PP + PP Q QP G P P + P
Sbjct: 126 GNRPQGPPPPGKPQGPPPQGDKSRSPR---SPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 182
Query: 699 RRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTP 758
Q P PPP P P +SQ PP P G QP PP
Sbjct: 183 PPQGGKKP--QGP--PPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPG 238
Query: 759 TPPSTPPLGKQNPSLPAPQTLAGGNPET--AQPHAGTLPRPRPVPKPR---NRPSVPPPP 813
P PP G P P P G P ++ + P +P P+ N P PPPP
Sbjct: 239 KPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPP 298
Score = 98.2 bits (243), Expect = 3e-20
Identities = 94/318 (29%), Positives = 112/318 (35%), Gaps = 45/318 (14%)
Query: 510 RGGTLNRKHISPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGP 569
+GG + P +P PP G P GP PP + P S QGP
Sbjct: 42 QGGNKPQGPPPPPGKPQGPPPQGGNK-PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP 100
Query: 570 SPGDGSPPK--PKDPVSAAVPAP-GRNNSQIASGQNQPQAAAGSHQLSMGQ---PHNAAG 623
P G+ P+ P P P P G N Q +PQ S P G
Sbjct: 101 PPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG 160
Query: 624 PSPHTLRRAVKKPAPAPPKPGNPPP---GHPGGQSSSGTSQHPPSLSPK------PPTRS 674
P P + + P P P KP PPP P G G Q PP K PP +
Sbjct: 161 PPPQGGNQP-QGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKP 219
Query: 675 PSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQG 734
PP Q QP G P P + P P Q N P PP
Sbjct: 220 QGPPPQGGNQPQGPPPPPGKPQGP--------PPQGGNKPQGPPP--------------- 256
Query: 735 PPNPMALPSEHGLE-QPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGT 793
P P P++ G + Q + +PP P P P NP P P AGGNP+ Q
Sbjct: 257 PGKPQGPPAQGGSKSQSARSPPGKPQGP--PQQEGNNPQGPPPP--AGGNPQQPQAPPAG 312
Query: 794 LPRPRPVPKPRNRPSVPP 811
P+ P P RPS PP
Sbjct: 313 QPQGPPRPPQGGRPSRPP 330
Score = 92.4 bits (228), Expect = 2e-18
Identities = 83/272 (30%), Positives = 101/272 (37%), Gaps = 53/272 (19%)
Query: 567 QGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSP 626
QGPSP G+ KP+ P P PG+ G N+PQ P GP P
Sbjct: 37 QGPSPQGGN--KPQGPP----PPPGKPQGPPPQGGNKPQGPP--------PPGKPQGPPP 82
Query: 627 HTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPP 686
+ + P P KP PPP GG G P PP + PP Q +P
Sbjct: 83 QGDKS--RSPRSPPGKPQGPPP--QGGNQPQGP--------PPPPGKPQGPPPQGGNRPQ 130
Query: 687 GQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHG 746
G P P + S SP P P PP QGPP P P G
Sbjct: 131 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN-------QPQGPPPPPGKP--QG 181
Query: 747 LEQPSHTPPQTPTPP----STPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPR--PRPV 800
PQ P PP PP G ++ S +P G P+ P G P+ P P
Sbjct: 182 PPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPP----GKPQGPPPQGGNQPQGPPPPP 237
Query: 801 PKPR-------NRPSVPPPP-QPPGVHSAGDS 824
KP+ N+P PPPP +P G + G S
Sbjct: 238 GKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGS 269
>gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapiens]
Length = 1502
Score = 100 bits (250), Expect = 5e-21
Identities = 62/198 (31%), Positives = 107/198 (54%), Gaps = 5/198 (2%)
Query: 246 EKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDC 305
E FG PL++ L + + I L +E CV + +TG+ EGL+R+ + ++ D
Sbjct: 1256 ESNYFGMPLQD-LVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQ 1314
Query: 306 STS-HLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTC 364
+ +L +AVAGALK++ +LP+PL+ ++L+ E + A + D+ ++L L
Sbjct: 1315 DHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIV 1374
Query: 365 QKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATS 424
+K P N+ FRY+I L +++Q +N MT N++I P L+ R + E + T
Sbjct: 1375 KKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLM--RPDFENREFLSTTK 1432
Query: 425 VHVVAVIEPIIQHADWFF 442
+H +V+E IQ +FF
Sbjct: 1433 IH-QSVVETFIQQCQFFF 1449
>gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapiens]
Length = 1501
Score = 100 bits (250), Expect = 5e-21
Identities = 62/198 (31%), Positives = 107/198 (54%), Gaps = 5/198 (2%)
Query: 246 EKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDC 305
E FG PL++ L + + I L +E CV + +TG+ EGL+R+ + ++ D
Sbjct: 1255 ESNYFGMPLQD-LVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQ 1313
Query: 306 STS-HLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTC 364
+ +L +AVAGALK++ +LP+PL+ ++L+ E + A + D+ ++L L
Sbjct: 1314 DHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIV 1373
Query: 365 QKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATS 424
+K P N+ FRY+I L +++Q +N MT N++I P L+ R + E + T
Sbjct: 1374 KKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLM--RPDFENREFLSTTK 1431
Query: 425 VHVVAVIEPIIQHADWFF 442
+H +V+E IQ +FF
Sbjct: 1432 IH-QSVVETFIQQCQFFF 1448
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 100 bits (250), Expect = 5e-21
Identities = 118/430 (27%), Positives = 156/430 (36%), Gaps = 113/430 (26%)
Query: 521 PAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPK 580
PA PP P +T P PP ++ S GG PS G P+P +PP PK
Sbjct: 943 PAATPPSPKGGPATPSPKWAPTPPAAT-PPSPKGGPATPSPKG----APTPPAATPPSPK 997
Query: 581 D----------PVSAAVPAPGRNNSQIAS----GQNQPQAAA--------GSHQLSMGQP 618
P AV P S A+ G + P AA + L G P
Sbjct: 998 GGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAP 1057
Query: 619 HNAA--------GPSPHTLRRAVKKPAPAPPKP-GNP---------------PPGHPGGQ 654
A GP+ +L+ A PA PP P G P PP GG
Sbjct: 1058 TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGL 1117
Query: 655 SS------------------SGTSQHPPSLSPKPPTRSPSPPTQHTGQPP--GQPSAPSQ 694
++ G + PP +P P +P P PP G P+ P+
Sbjct: 1118 ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1177
Query: 695 L-SAPRRYSSSLSPIQAPNHPPPQPPTQ----ATPLMHTKPNSQG--PPNP---MALPSE 744
+P+ ++ SP AP P PP+ ATP P + PP+P +A PS
Sbjct: 1178 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1237
Query: 745 HGL-EQPSHTPPQ------------TPTPP-STPP-----------LGKQNPSLPAPQTL 779
G P+ TPP PTPP +TPP G NP++ P +
Sbjct: 1238 KGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP 1297
Query: 780 AGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPP---PQPPGV---HSAGDSSLTNTAPTA 833
GG P T+ P P P P+ P PPP P PP V G +L T P++
Sbjct: 1298 KGG-PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSS 1356
Query: 834 SKIVTDSNSR 843
T +S+
Sbjct: 1357 KGGPTTPSSK 1366
Score = 94.7 bits (234), Expect = 3e-19
Identities = 92/388 (23%), Positives = 146/388 (37%), Gaps = 58/388 (14%)
Query: 520 SPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKP 579
+PA PP P +T P G PP ++ S GG P G P+P +PP P
Sbjct: 1243 TPAATPPSPKGGPATPPPKGAPTPPAAT-PPSLKGGLATPPHKG----APNPAVVTPPSP 1297
Query: 580 KD------------PVSAAVPAP-GRNNSQIASGQNQPQAAA-----GSHQLSMGQPHNA 621
K P +A P+P G + G P A G+ L P +
Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK 1357
Query: 622 AGPSPHTLRRAVKKPAPAPPKPGNP---PPGHPGGQSSSGTSQHP--PSLSPKPPTRSPS 676
GP+ + + PA P G P PP G + P P++ P P ++P+
Sbjct: 1358 GGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA 1417
Query: 677 PPTQHTGQPPGQ-----PSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMH--TK 729
P G P A + +S + ++S AP P P ++ P + T
Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPATS-----APKGGPATPSSKGDPTLPAVTP 1472
Query: 730 PNSQGPPNPMALPSEHGLEQPSHTPPQTPTP------PSTP------PLGKQNPSLPAPQ 777
P+ + PP P + + ++ TP P PS+P P +++P P
Sbjct: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532
Query: 778 TLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIV 837
L+ P T P +P VP P+ P++P P + P S+ ++S +P A +
Sbjct: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEAS----SPPA--VT 1586
Query: 838 TDSNSRVSEPHRSIFPEMHSDSASKDVP 865
+ P + P + + K+ P
Sbjct: 1587 PSTYKGAPSPKELLIPPAVTSPSPKEAP 1614
Score = 89.0 bits (219), Expect = 2e-17
Identities = 99/375 (26%), Positives = 138/375 (36%), Gaps = 43/375 (11%)
Query: 520 SPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKP 579
+PA PP P +T P G P ++ S GG PS G P+ +PP P
Sbjct: 1197 TPAATPPSPKGGLATPSPKGAPTTPAAT-PPSPKGGLATPSPKG----APTTPAATPPSP 1251
Query: 580 KD-----PVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVK 634
K P A P + G P + + P GP+ + A
Sbjct: 1252 KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311
Query: 635 KPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQ 694
PA PP P G PG G + PP+++P P +P+ P T G P+ PS
Sbjct: 1312 PPAATPPS----PKGSPGTPPPKG-APTPPAVTPPSPKGTPTLPAT-TPSSKGGPTTPSS 1365
Query: 695 LSAPRRYSSSLSPIQAPNHPPPQPPT-QATPLMHTKPNS---------QGPPNPM----- 739
P +++ S P PP P A P P S + P P+
Sbjct: 1366 KEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGA 1425
Query: 740 ALPSEHGLEQPSHTP------PQTPTPPSTP--PLGKQNPSLPAPQTLAGGNPET-AQPH 790
A PS+ L P+ TP P T P P P K +P+LPA + P Q
Sbjct: 1426 ATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVA 1485
Query: 791 AGTLPRPRP-VPKPRNRPSVPP--PPQPPGVHSAGDSSLTNTAPTASKIVTDSNSRVSEP 847
+ P+ P P P P++P P P V + S APTA+ + + + ++
Sbjct: 1486 TSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPK 1545
Query: 848 HRSIFPEMHSDSASK 862
I P M S K
Sbjct: 1546 EALIPPAMTVPSPKK 1560
Score = 84.3 bits (207), Expect = 4e-16
Identities = 89/333 (26%), Positives = 120/333 (36%), Gaps = 53/333 (15%)
Query: 528 PPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAV 587
P T S P+ P S+ S G T+P ++ P+P + P PK+ A
Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPP-----KETPTPSVVNLPFPKE--GPAT 902
Query: 588 PAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNP- 646
PAP + ++ + P+ A + G P A PSP K AP PP P
Sbjct: 903 PAP-KQAPALSMTSSSPKKARAT-PAPKGIP---ASPSP--------KGAPTPPAATPPS 949
Query: 647 PPGHPGGQSSSGTSQHPPSLSPKP--------PTRSPSPPTQHTGQPPGQPSAPSQLSAP 698
P G P S P + P P P +P+PP P G P+ PS AP
Sbjct: 950 PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAP 1009
Query: 699 RRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTP 758
P P P P P + P + PP+P P+ L + + T P
Sbjct: 1010 ------TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAAT 1063
Query: 759 TP-----PSTPPL-GKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPP- 811
P P+TP L G P P + GG P T P +P P P+ + PP
Sbjct: 1064 LPSPKGGPATPSLKGAPTPPAATPPSPKGG-PATPSPKGAPMPPAATPPSPKGGLATPPH 1122
Query: 812 ----------PPQPPGVHSAGDSSLTNTAPTAS 834
PP P G + T P A+
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1155
Score = 83.6 bits (205), Expect = 8e-16
Identities = 95/348 (27%), Positives = 127/348 (36%), Gaps = 45/348 (12%)
Query: 510 RGGTLNRKHISPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGP 569
+G TL K LP PA + P S + S P+ GI P
Sbjct: 876 KGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGI-PASP 934
Query: 570 SP-GDGSPPKPKDPVSAAVPA----------PGRNNSQIASGQNQPQAAAGSHQLSMGQP 618
SP G +PP P PA P G P + P
Sbjct: 935 SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP 994
Query: 619 HNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPP 678
GP+ + + A PA PP P P P + +S PP+ +P P SP+
Sbjct: 995 SPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS----TPPAATPPSPKGSPAA- 1049
Query: 679 TQHTGQPPGQPSAP-SQLSAPRRYSSSLSPIQAPNHP---PPQP---PTQATPLMHTKPN 731
T P G P+ P + L +P+ ++ S AP P PP P P +P P
Sbjct: 1050 ---TPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106
Query: 732 SQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHA 791
+ PP+P + GL P H T TP +TPP K + P P+ G P T A
Sbjct: 1107 AATPPSP-----KGGLATPPHKGAPT-TPAATPPSPKGGLATPPPK----GAPTTP---A 1153
Query: 792 GTLPRPR---PVPKPRNRPSVP--PPPQPPGVHSAGDSSLTNTAPTAS 834
T P P+ P P+ P+ P PP P G + T P A+
Sbjct: 1154 ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1201
Score = 82.0 bits (201), Expect = 2e-15
Identities = 95/345 (27%), Positives = 130/345 (37%), Gaps = 37/345 (10%)
Query: 520 SPAFQPPLPPTDGSTVVPAGPEPPPQSS-----RAESSSGGGTVPSSAGILEQGPSPGDG 574
SP P PP G+ PA P P+ + SS GG T PSS ++GP+P
Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS----KEGPTPPAA 1374
Query: 575 SPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAG---SHQLSMGQP---HNAAGPSPHT 628
+P P A P + I S + P + A S + + P AA PS
Sbjct: 1375 TPSHKGGP--AMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432
Query: 629 LRRAVKKPAPAPPKPG-NPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPG 687
L P P + P G P SS G P +++P P P+P T P
Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLP-AVTPPSPKEPPAPKQVATSSSPK 1491
Query: 688 Q-PSAPSQLSAPRRYSS-SLSPIQAPNHPP----PQPPTQATPLMHTKPNSQGP-----P 736
+ P+ P+ + AP + SP + P P P PT AT L P + P P
Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPT-ATLLSKKTPATLAPKEALIP 1550
Query: 737 NPMALPSEHGLEQPS-HTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLP 795
M +PS + P+ TP + P PS+ P+ A E P A T P
Sbjct: 1551 PAMTVPSPK--KTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP 1608
Query: 796 RPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIVTDS 840
P+ P P P+V PP G + + P + DS
Sbjct: 1609 SPKEAPTP---PAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDS 1650
Score = 73.2 bits (178), Expect = 1e-12
Identities = 98/373 (26%), Positives = 143/373 (38%), Gaps = 71/373 (19%)
Query: 526 PLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPS-PGDGSPPKPK--DP 582
PL PT S P P P + + +P S PS P G+PP K D
Sbjct: 699 PLVPT-ASENCPVAPSPQNTCAPLATLVLAPEIPKSV----PSPSLPPAGTPPGTKKVDG 753
Query: 583 VS-AAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGP-----SPHTLRRAVKKP 636
+S + AP ++ + ++ +A S + ++ ++ P SP T R KK
Sbjct: 754 ISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKG 813
Query: 637 APAPPKP-GN-PPPGHP--------------GGQSSSGTSQHPPSLSPK----------- 669
+ P P GN P P G + S T+ P SPK
Sbjct: 814 SAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPL 873
Query: 670 -------PPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQA 722
PP +P+P + P P+ P+ AP +S SP +A P P+
Sbjct: 874 SPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKG---- 929
Query: 723 TPLMHTKPNSQGPPNPMAL--PSEHGLEQPSHTPPQTPTPP-STPPLGKQNPSLPAPQTL 779
+ P+ +G P P A PS G + +P PTPP +TPP K P+ P+P+
Sbjct: 930 ---IPASPSPKGAPTPPAATPPSPKG-GPATPSPKWAPTPPAATPPSPKGGPATPSPK-- 983
Query: 780 AGGNPETAQPHAGTLPRPR---PVPKPRNRPSVP--PPPQPPGVHSAGDSSLTNTAPTAS 834
G P P A T P P+ P P+ P+ P PP P G +A + P A+
Sbjct: 984 --GAP---TPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAA 1038
Query: 835 KIVTDSNSRVSEP 847
+ S + P
Sbjct: 1039 TPPSPKGSPAATP 1051
Score = 67.4 bits (163), Expect = 6e-11
Identities = 103/389 (26%), Positives = 143/389 (36%), Gaps = 76/389 (19%)
Query: 519 ISPAFQPPLPPT-DGSTVVPAGPEPPP--------QSSRAESSSGGGTVPSSAGILEQGP 569
+SP P P T +G+ G PP ++ + GG PSS G P
Sbjct: 1410 LSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG----DP 1465
Query: 570 SPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTL 629
+ +PP PK+P PAP Q+A+ + +A A P P+ +
Sbjct: 1466 TLPAVTPPSPKEP-----PAP----KQVATSSSPKKAPA--------TPAPMGAPTLPAV 1508
Query: 630 RRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQP 689
+ K PA P P S T P +L+PK + PP P P
Sbjct: 1509 IPSSPKEVPATPSSRRDPIAPTATLLSKKT---PATLAPK---EALIPPAMTVPSPKKTP 1562
Query: 690 SAPSQLSAPRRYSS-------SLSPIQAPNHPPPQ----PP--TQATPLMHTKPNSQGPP 736
+ P+ AP SS +++P P P+ PP T +P P + PP
Sbjct: 1563 AIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPP 1622
Query: 737 NPMALPSEHGLEQPSHTPPQTPT-PPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLP 795
+P E G P+ P TPT PP TP K +P+ PA T G P A
Sbjct: 1623 SP-----EKGPATPA--PKGTPTSPPVTPSSLKDSPTSPASVTCKMG---ATVPQASKGL 1672
Query: 796 RPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIVTDSNSRVSEPHRSIFPEM 855
+ P V P P +S+ TAPT T +S S P I P+
Sbjct: 1673 PAKKGPTALKEVLVAPAP---------ESTPIITAPTRKGPQTKKSSATSPP---ICPDP 1720
Query: 856 HSDSASK----DVPGRILLDIDNDTESTA 880
+ + SK V LL + D+ TA
Sbjct: 1721 SAKNGSKGPLSTVAPAPLLPVQKDSSKTA 1749
Score = 57.4 bits (137), Expect = 6e-08
Identities = 88/381 (23%), Positives = 131/381 (34%), Gaps = 66/381 (17%)
Query: 519 ISPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSS----------------- 561
I PA P P + +P E P S E+SS PS+
Sbjct: 1549 IPPAMTVPSPKK--TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVT 1606
Query: 562 AGILEQGPSPGDGSPPKPKDPVSAAVP-----APGRNNSQIASGQNQPQAA-----AGSH 611
+ ++ P+P +PP P+ + P +P S + P + A
Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVP 1666
Query: 612 QLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPP 671
Q S G P A P L+ + PAP P P G Q+ ++ PP + P P
Sbjct: 1667 QASKGLP---AKKGPTALKEVLVAPAPEST-PIITAPTRKGPQTKKSSATSPP-ICPDPS 1721
Query: 672 TRSPSPPTQHTGQP----PGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQAT---- 723
++ S T P P Q + S P+ P P T A
Sbjct: 1722 AKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKV 1781
Query: 724 -PLMHTKPNSQGPPNPMALPSEHGLEQPSHT-PPQTPTPPSTPPLGKQNPSLP------- 774
P + S P P++LP P T PP+ PS+P L ++PS P
Sbjct: 1782 LPKPESASVSAAPSPPVSLPLA---PSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADED 1838
Query: 775 ------APQTLAGGNPETAQPHAGTLPRPR----PVPKPRNRPSVPPPPQPPGVHSAGDS 824
P+ ++GG P Q +P P+ PVP P + V + G S D
Sbjct: 1839 ELLPLIPPEPISGGVP--FQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDE 1896
Query: 825 SLTNTAPTASKIVTDSNSRVS 845
S+ S T ++++
Sbjct: 1897 SVPELEEQDSTQATTQQAQLA 1917
Score = 46.2 bits (108), Expect = 1e-04
Identities = 60/247 (24%), Positives = 90/247 (36%), Gaps = 23/247 (9%)
Query: 600 GQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGT 659
G+ A +L Q A P L A P P PPP P Q +
Sbjct: 3 GEATETVPATEQELPQPQAETAVLPMSSALSVTA---ALGQPGPTLPPPCSPAPQQCPLS 59
Query: 660 SQHPPSLSPKPPTRSPSP-------PTQHTGQPPG-QPSAPSQLSAPRRYSSSLSPIQAP 711
+ + S P P T + +P + T P G P AP+ L P +SP
Sbjct: 60 AANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFL--PNLIGPPISPAALA 117
Query: 712 NHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNP 771
P PT + P+S P +AL + H +++ S PP T P + + +
Sbjct: 118 LASPMIAPT-----LKGTPSSSAPLALVAL-APHSVQKSSAFPPNLLTSPPSVAVAESGS 171
Query: 772 SLPAPQTLAGGNPET--AQPHAGTLPRPRPVPKPRNRPSVPP--PPQPPGVHSAGDSSLT 827
+ +A P+T + + +P P+ P P S P P +G +SL
Sbjct: 172 VITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLP 231
Query: 828 NTAPTAS 834
T PT +
Sbjct: 232 QTTPTTT 238
Score = 44.3 bits (103), Expect = 5e-04
Identities = 60/236 (25%), Positives = 80/236 (33%), Gaps = 41/236 (17%)
Query: 625 SPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQ 684
SP KK P P P QS+S + + P S +S P
Sbjct: 545 SPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPL----- 599
Query: 685 PPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQ------------PPTQATPLMHTKPNS 732
P G+P+ S +++P +SS S I+ ++ P P A PL P
Sbjct: 600 PIGKPA--SSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAG 657
Query: 733 QGPPNPMALPSEHGLEQP------SHTPPQTP-------TPPSTPPLGKQNPSLPAPQTL 779
P + P S P P T P P + P P+PQ
Sbjct: 658 VAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQN- 716
Query: 780 AGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSA-GDSSLTNTAPTAS 834
T P A + P +PK PS+PP PPG G S + AP AS
Sbjct: 717 ------TCAPLATLVLAPE-IPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVAS 765
Score = 42.7 bits (99), Expect = 0.001
Identities = 97/401 (24%), Positives = 141/401 (35%), Gaps = 81/401 (20%)
Query: 529 PTDGSTVVPAGPE--PPPQSSRAESSSGGGTVPSSAGILEQGPS-PGDGSPPKPKDPVSA 585
P + + VPA + P PQ+ A + +A + + GP+ P SP + P+SA
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSA-LSVTAALGQPGPTLPPPCSPAPQQCPLSA 60
Query: 586 AVPA-PGRNNSQIASGQNQ---PQAAAGSHQLSMGQPH-------NAAGPSPHTLRRAVK 634
A A P + S IAS + PQ+++G+ L +G N GP A+
Sbjct: 61 ANQASPFPSPSTIASTPLEVPFPQSSSGT-ALPLGTAPEAPTFLPNLIGPPISPAALALA 119
Query: 635 KPAPAPPKPGNPPPGHP------GGQSSSGTSQHPPSLSPKPPTRS-------------- 674
P AP G P P S +S PP+L PP+ +
Sbjct: 120 SPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPI 179
Query: 675 -PSPPTQHTGQ--------PPGQPSAPSQLS-APRRYSSSLSPIQAPNHPPPQPPTQATP 724
PS P + + P G PS P +S P + ++ IQ+ PQ T T
Sbjct: 180 APSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQ-TTPTTT 238
Query: 725 LMHTKP--------------------NSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTP 764
L P + +GP +P A S P T Q P+TP
Sbjct: 239 LAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTP 298
Query: 765 P-----LGK-----QNPSLPAPQTLAGGNPET-AQPHAGTLP---RPRPVPKPRNRPSVP 810
P LG S + Q L P + P T+ P R +P
Sbjct: 299 PDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIP 358
Query: 811 PPPQPPGVHSAGDSSLTNTAPTASKIVTDSNSRVSEPHRSI 851
P P V A ++ AP+ K + +S P S+
Sbjct: 359 PLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSL 399
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 100 bits (249), Expect = 6e-21
Identities = 61/202 (30%), Positives = 105/202 (51%), Gaps = 11/202 (5%)
Query: 261 SGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLD---EFYSDP 317
+ R I L ++ C L+ E G++ G++R+ + + ++ L+ + +D + + D
Sbjct: 1157 TNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDL 1216
Query: 318 HAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRY 377
+ ++ LKS+ R+LPEPL T + Y ++ + +D +L+ L R LP ++ ++
Sbjct: 1217 NVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETLKF 1276
Query: 378 LIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATSVHVVAVIEPIIQH 437
L L +A+ S+ NKM P N+AIV GP L+ +E + M ++E +IQH
Sbjct: 1277 LSAHLKTVAENSEKNKMEPRNLAIVFGPTLV-RTSEDNMTHMVTHMP-DQYKIVETLIQH 1334
Query: 438 ADWFFPEEVEFNVSEAFVPLTT 459
DWFF EE A PLTT
Sbjct: 1335 HDWFFTEE------GAEEPLTT 1350
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 100 bits (249), Expect = 6e-21
Identities = 87/291 (29%), Positives = 104/291 (35%), Gaps = 50/291 (17%)
Query: 537 PAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPG----DGSPPKPKDPVSAAVPAPGR 592
P PPP GG QGP P +G PP+ + P PG+
Sbjct: 47 PQRTPPPPGKPEGRPPQGGNQ--------SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGK 98
Query: 593 NNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPG 652
Q G NQ Q +P GP P ++ + P P P KP PPP G
Sbjct: 99 PEGQPPQGGNQSQGPPP-------RPGKPEGPPPQGGNQS-QGPPPRPGKPEGPPP--QG 148
Query: 653 GQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPP--GQPSAPSQLSAPRRYSSSLSPIQA 710
G S G PP KP P Q G PP G+P P P+ + S P
Sbjct: 149 GNQSQG----PPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPP----PQGGNQSQGPPPR 200
Query: 711 PNHPPPQPPTQATPLMHTKPNSQGPP----NPMALPSEHGLEQPSHTPPQTPTPPSTPPL 766
P P PP SQGPP P PS+ G +P PP P PP
Sbjct: 201 PGKPEGPPPQGGN-------QSQGPPPRPGKPEGPPSQGG-NKPQGPPPHPGKPQGPPPQ 252
Query: 767 GKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPG 817
P P P G P+ P G +P+P P +P PPPP G
Sbjct: 253 EGNKPQRPPPP----GRPQGPPPPGGN--PQQPLPPPAGKPQGPPPPPQGG 297
Score = 98.2 bits (243), Expect = 3e-20
Identities = 92/316 (29%), Positives = 110/316 (34%), Gaps = 58/316 (18%)
Query: 510 RGGTLNRKHISPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGP 569
+GG ++ P +P P G PPP+ + E P G QGP
Sbjct: 42 QGGNQPQRTPPPPGKPEGRPPQGGN---QSQGPPPRPGKPEGP------PPQGGNQSQGP 92
Query: 570 SPG----DGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPS 625
P +G PP+ + P PG+ G NQ Q +P GP
Sbjct: 93 PPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPP-------RPGKPEGPP 145
Query: 626 PHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPP-----TRSPSPPTQ 680
P ++ + P P P KP PPP GG S G HP PP ++ P P
Sbjct: 146 PQGGNQS-QGPPPRPGKPEGPPP--QGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPG 202
Query: 681 HTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMA 740
PP Q SQ PR P Q N P PP P QGPP
Sbjct: 203 KPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKP--------QGPP---- 250
Query: 741 LPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPV 800
P E PQ P PP P Q P P GGNP+ P P+ P
Sbjct: 251 -PQE-------GNKPQRPPPPGRP----QGPPPP------GGNPQQPLPPPAGKPQGPPP 292
Query: 801 PKPRNRPSVPPPPQPP 816
P RP PP QPP
Sbjct: 293 PPQGGRPHRPPQGQPP 308
Score = 85.5 bits (210), Expect = 2e-16
Identities = 79/275 (28%), Positives = 97/275 (35%), Gaps = 48/275 (17%)
Query: 569 PSPG--DGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSP 626
P PG +G PP+ + P PG+ G NQ Q GQP S
Sbjct: 52 PPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQS- 110
Query: 627 HTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPP 686
+ P P P KP PPP GG S G P P + PP Q Q
Sbjct: 111 -------QGPPPRPGKPEGPPP--QGGNQSQGP--------PPRPGKPEGPPPQGGNQSQ 153
Query: 687 GQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPP----NPMALP 742
G P P + P + S PPP P P SQGPP P P
Sbjct: 154 GPPPRPGKPEGPPPQGGNQS-----QGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPP 208
Query: 743 SEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPR-PVP 801
+ G + S PP P P PP + G P+ PH G +P+ P P
Sbjct: 209 PQGGNQ--SQGPPPRPGKPEGPP------------SQGGNKPQGPPPHPG---KPQGPPP 251
Query: 802 KPRNRPS-VPPPPQPPGVHSAGDSSLTNTAPTASK 835
+ N+P PPP +P G G + P A K
Sbjct: 252 QEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGK 286
Score = 30.8 bits (68), Expect = 5.8
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 8/46 (17%)
Query: 778 TLAGGNPETAQPHAGTLPRPRPVP--KPRNRP------SVPPPPQP 815
++ G PE +P G P+ P P KP RP S PPP+P
Sbjct: 30 SVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRP 75
>gi|21314774 T-cell activation Rho GTPase-activating protein isoform
b [Homo sapiens]
Length = 731
Score = 100 bits (248), Expect = 8e-21
Identities = 104/421 (24%), Positives = 173/421 (41%), Gaps = 54/421 (12%)
Query: 268 PIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSY 327
PI+ + +L G EG+FR A K+LK L+ S +D H +A K +
Sbjct: 103 PIQDILTILCLKGPSTEGIFRRAANEKARKELKEELN-SGDAVDLERLPVHLLAVVFKDF 161
Query: 328 LRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQ 387
LR +P L++ +L+EEW +QD++ +++ L + KLP N + ++L+ L +++
Sbjct: 162 LRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISK 221
Query: 388 TSDVNKMTPSNIAIVLGPNLLWARNEGTLA-EMAAATSVHVVAVIEPIIQHADWFFPEEV 446
S+VN+M SN+AI +GPN+L N+ +L+ E + V ++E +I + F E +
Sbjct: 222 NSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENI 281
Query: 447 EFNVSEAFVPLTTPSSNHSFHTGNDSDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQ 506
HS T +DS LE + ++ ++ D ++ D +
Sbjct: 282 PV---------------HSSITSDDS----LEHTDSSDVSTLQND----SAYDSNDPDVE 318
Query: 507 AHRRGGTLNRKHISPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILE 566
++ G SP+ QP +P + + AG PQ +R S + S+ L+
Sbjct: 319 SNSSSGI-----SSPSRQPQVPMATAAGLDSAG----PQDAREVSPE---PIVSTVARLK 366
Query: 567 QGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQ-PQAAAGSHQLSMGQPHNAAGPS 625
+ D +P P S N + + P GS + A P
Sbjct: 367 SSLAQPDRRYSEPSMPSSQECLESRVTNQTLTKSEGDFPVPRVGSRL----ESEEAEDPF 422
Query: 626 PHTLRRAV--KKPAPAPPKPGNPPPGHP----------GGQSSSGTSQHPPSLSPKPPTR 673
P + AV K P K N PG S +S P SP P R
Sbjct: 423 PEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRALVLKAFSSSSLDASSDSSPVASPSSPKR 482
Query: 674 S 674
+
Sbjct: 483 N 483
>gi|4505507 oligophrenin 1 [Homo sapiens]
Length = 802
Score = 100 bits (248), Expect = 8e-21
Identities = 117/453 (25%), Positives = 186/453 (41%), Gaps = 90/453 (19%)
Query: 246 EKPAFGTPLEEHLKRSGREIALP-IEACVMLLLETGMKEEGLFR-IGAGASKLKKLKAAL 303
++P + +P+ + + E+ + C+ ++ G+K EGL+R +G+ K L A
Sbjct: 366 KEPIYHSPITKQQEMELNEVGFKFVRKCINIIETKGIKTEGLYRTVGSNIQVQKLLNAFF 425
Query: 304 DCSTSHLDEFYS---DPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDL 360
D +F++ D + +LK YLR L EP+MT+ L++E A + D +L +
Sbjct: 426 DPKCPGDVDFHNSDWDIKTITSSLKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAI 485
Query: 361 WRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMA 420
KLP +N LI+ L + + S N MTPSN+ ++ GP L+ A+ E T+A M
Sbjct: 486 HSLVYKLPEKNREMLELLIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQ-EDTVAAMM 544
Query: 421 AATSVHVVAVIEPIIQHADWFF---PEEVEFNVSEAFVPLTTPSSNHSFHTGNDSDSGTL 477
++ V+E +I+H + PEE A P+ P T
Sbjct: 545 NIKFQNI--VVEILIEHFGKIYLGPPEE------SAAPPVPPPRV-------------TA 583
Query: 478 ERKRPASMA---VMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGST 534
R +P +++ + E + S + Q GT I+ + +PP PP
Sbjct: 584 RRHKPITISKRLLRERTVFYTSSLDESEDEIQHQTPNGT-----ITSSIEPPKPPQH--- 635
Query: 535 VVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAP---- 590
P+ P Q S G T PG SP +P P P
Sbjct: 636 -----PKLPIQRS-------GET------------DPGRKSPSRPILD-GKLEPCPEVDV 670
Query: 591 GRNNSQIASGQNQ--PQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPP 648
G+ S++ G + P+A G P +GP+ T +K+PAP P
Sbjct: 671 GKLVSRLQDGGTKITPKATNG--------PMPGSGPT-KTPSFHIKRPAP------RPLA 715
Query: 649 GHPGGQSSSGTSQHPPSLSP---KPPTRSPSPP 678
H G + S + PP P +PP R P PP
Sbjct: 716 HHKEGDADSFSKVRPPGEKPTIIRPPVRPPDPP 748
Score = 33.1 bits (74), Expect = 1.2
Identities = 37/146 (25%), Positives = 54/146 (36%), Gaps = 31/146 (21%)
Query: 665 SLSPKPPTRSPSPPTQHTGQ-PPGQ--PSAP---------------SQLSAPRRYSSSLS 706
S+ P P + P P Q +G+ PG+ PS P +S + + ++
Sbjct: 626 SIEPPKPPQHPKLPIQRSGETDPGRKSPSRPILDGKLEPCPEVDVGKLVSRLQDGGTKIT 685
Query: 707 PIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPP--------QTP 758
P +A N P P TP H K + P P+A E + S P + P
Sbjct: 686 P-KATNGPMPGSGPTKTPSFHIK---RPAPRPLAHHKEGDADSFSKVRPPGEKPTIIRPP 741
Query: 759 TPPSTPPLGKQNPSLPAPQ-TLAGGN 783
P PP P P P+ + GN
Sbjct: 742 VRPPDPPCRAATPQKPEPKPDIVAGN 767
>gi|229094128 active breakpoint cluster region-related protein
isoform c [Homo sapiens]
Length = 813
Score = 98.6 bits (244), Expect = 2e-20
Identities = 61/203 (30%), Positives = 104/203 (51%), Gaps = 8/203 (3%)
Query: 250 FGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSH 309
FG + KR ++ + CV + + G++E G++RI A+ ++ LKA D +
Sbjct: 599 FGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKD 658
Query: 310 LDEFYSDP--HAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKL 367
+ SD +A+AG LK Y RELPEPL+T LY + + ++ D K + + L
Sbjct: 659 ILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSL 718
Query: 368 PPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATSV-- 425
P N + F +L++ L ++A+ +NKM+ N+A V GP LL + A + +A +
Sbjct: 719 PDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWS 778
Query: 426 -HVVAVIEPI---IQHADWFFPE 444
V+A ++ + +QH F E
Sbjct: 779 HDVMAQVQVLLYYLQHPPISFAE 801
>gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens]
Length = 1136
Score = 98.6 bits (244), Expect = 2e-20
Identities = 67/248 (27%), Positives = 112/248 (45%), Gaps = 27/248 (10%)
Query: 223 HRKALAVLEKTLPEMRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMK 282
H+K L +TL H+ FG + + + ++ CV + ++
Sbjct: 736 HKKCL----ETLAIQCGHKKLQGRLQLFGQDFSHAARSAPDGVPFIVKKCVCEIERRALR 791
Query: 283 EEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYE 342
+G++R+ ++++KL A + ++ + PH ++ LK YLR+LPEPL++F LY
Sbjct: 792 TKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPLISFRLYH 851
Query: 343 EWTQV--------ASVQDQDKKLQD--------------LWRTCQKLPPQNFVNFRYLIK 380
E + A + + QD L + LPP+N + +YL++
Sbjct: 852 ELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVALAGRLRELLRDLPPENRASLQYLLR 911
Query: 381 FLAKLAQTSDVNKMTPSNIAIVLGPNLLWAR-NEGTLAEMAAATSVHVVAVIEPIIQHAD 439
L ++ + NKMTP N+ IV GP LL R E T++ + H VIE +I H
Sbjct: 912 HLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSLSSLVDYPHQARVIETLIVHYG 971
Query: 440 WFFPEEVE 447
F EE E
Sbjct: 972 LVFEEEPE 979
>gi|38679957 active breakpoint cluster region-related protein
isoform a [Homo sapiens]
Length = 859
Score = 98.6 bits (244), Expect = 2e-20
Identities = 61/203 (30%), Positives = 104/203 (51%), Gaps = 8/203 (3%)
Query: 250 FGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSH 309
FG + KR ++ + CV + + G++E G++RI A+ ++ LKA D +
Sbjct: 645 FGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKD 704
Query: 310 LDEFYSDP--HAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKL 367
+ SD +A+AG LK Y RELPEPL+T LY + + ++ D K + + L
Sbjct: 705 ILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSL 764
Query: 368 PPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATSV-- 425
P N + F +L++ L ++A+ +NKM+ N+A V GP LL + A + +A +
Sbjct: 765 PDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWS 824
Query: 426 -HVVAVIEPI---IQHADWFFPE 444
V+A ++ + +QH F E
Sbjct: 825 HDVMAQVQVLLYYLQHPPISFAE 847
>gi|38679954 active breakpoint cluster region-related protein
isoform b [Homo sapiens]
Length = 822
Score = 98.6 bits (244), Expect = 2e-20
Identities = 61/203 (30%), Positives = 104/203 (51%), Gaps = 8/203 (3%)
Query: 250 FGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSH 309
FG + KR ++ + CV + + G++E G++RI A+ ++ LKA D +
Sbjct: 608 FGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKD 667
Query: 310 LDEFYSDP--HAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKL 367
+ SD +A+AG LK Y RELPEPL+T LY + + ++ D K + + L
Sbjct: 668 ILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSL 727
Query: 368 PPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATSV-- 425
P N + F +L++ L ++A+ +NKM+ N+A V GP LL + A + +A +
Sbjct: 728 PDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWS 787
Query: 426 -HVVAVIEPI---IQHADWFFPE 444
V+A ++ + +QH F E
Sbjct: 788 HDVMAQVQVLLYYLQHPPISFAE 810
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,994,967
Number of Sequences: 37866
Number of extensions: 3291455
Number of successful extensions: 64699
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 926
Number of HSP's successfully gapped in prelim test: 2880
Number of HSP's that attempted gapping in prelim test: 17936
Number of HSP's gapped (non-prelim): 20723
length of query: 881
length of database: 18,247,518
effective HSP length: 111
effective length of query: 770
effective length of database: 14,044,392
effective search space: 10814181840
effective search space used: 10814181840
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.