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Search of human proteins with 53829385
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|53829385 leucine rich repeat containing 37B [Homo sapiens]
(947 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|53829385 leucine rich repeat containing 37B [Homo sapiens] 1921 0.0
gi|239740955 PREDICTED: similar to c114 SLIT-like testicular pro... 759 0.0
gi|239740953 PREDICTED: similar to c114 SLIT-like testicular pro... 759 0.0
gi|110665701 leucine rich repeat containing 37A [Homo sapiens] 755 0.0
gi|75677612 leucine rich repeat containing 37, member A3 [Homo s... 753 0.0
gi|116325993 c114 SLIT-like testicular protein [Homo sapiens] 752 0.0
gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo ... 484 e-136
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 67 6e-11
gi|27436867 slit and trk like 4 protein [Homo sapiens] 67 6e-11
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 67 8e-11
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 67 8e-11
gi|85986601 relaxin/insulin-like family peptide receptor 1 [Homo... 66 1e-10
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 65 2e-10
gi|10190722 leucine-rich repeats and transmembrane domains 1 [Ho... 65 4e-10
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 64 9e-10
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 64 9e-10
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 64 9e-10
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 64 9e-10
gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo sa... 64 9e-10
gi|4759146 slit homolog 2 [Homo sapiens] 62 2e-09
gi|156139147 leucine rich repeat transmembrane neuronal 4 isofor... 62 3e-09
gi|197927168 leucine rich repeat transmembrane neuronal 4 isofor... 62 3e-09
gi|7662320 leucine-rich repeats and immunoglobulin-like domains ... 62 3e-09
gi|40255157 leucine-rich repeats and immunoglobulin-like domains... 62 3e-09
gi|209862903 leucine-rich repeats and immunoglobulin-like domain... 62 3e-09
gi|194272183 G protein-coupled receptor 124 [Homo sapiens] 61 6e-09
gi|110349719 titin isoform N2-A [Homo sapiens] 60 7e-09
gi|188528675 slit homolog 1 [Homo sapiens] 60 7e-09
gi|221136985 SLIT and NTRK-like family, member 2 [Homo sapiens] 60 1e-08
gi|221136981 SLIT and NTRK-like family, member 2 [Homo sapiens] 60 1e-08
>gi|53829385 leucine rich repeat containing 37B [Homo sapiens]
Length = 947
Score = 1921 bits (4976), Expect = 0.0
Identities = 947/947 (100%), Positives = 947/947 (100%)
Query: 1 MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSSRSSHLPWESP 60
MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSSRSSHLPWESP
Sbjct: 1 MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSSRSSHLPWESP 60
Query: 61 HAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQD 120
HAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQD
Sbjct: 61 HAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQD 120
Query: 121 LNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVS 180
LNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVS
Sbjct: 121 LNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVS 180
Query: 181 RPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPE 240
RPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPE
Sbjct: 181 RPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPE 240
Query: 241 LRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQ 300
LRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQ
Sbjct: 241 LRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQ 300
Query: 301 QEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNET 360
QEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNET
Sbjct: 301 QEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNET 360
Query: 361 ESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLD 420
ESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLD
Sbjct: 361 ESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLD 420
Query: 421 LELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQT 480
LELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQT
Sbjct: 421 LELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQT 480
Query: 481 LHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTSTNICELCTCGDETLSCVGLSPKQ 540
LHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTSTNICELCTCGDETLSCVGLSPKQ
Sbjct: 481 LHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTSTNICELCTCGDETLSCVGLSPKQ 540
Query: 541 RLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFE 600
RLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFE
Sbjct: 541 RLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFE 600
Query: 601 GLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLI 660
GLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLI
Sbjct: 601 GLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLI 660
Query: 661 LNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILTMTVELEKLILPSHMACCLCQ 720
LNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILTMTVELEKLILPSHMACCLCQ
Sbjct: 661 LNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILTMTVELEKLILPSHMACCLCQ 720
Query: 721 FKNSIEAVCKTVKLHCNTACLTNSIHCPEEASVGNPEGAFMKMLQARKQHMSTQLTIESE 780
FKNSIEAVCKTVKLHCNTACLTNSIHCPEEASVGNPEGAFMKMLQARKQHMSTQLTIESE
Sbjct: 721 FKNSIEAVCKTVKLHCNTACLTNSIHCPEEASVGNPEGAFMKMLQARKQHMSTQLTIESE 780
Query: 781 APSDSSGINLSGFGGDQLEIQLTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCA 840
APSDSSGINLSGFGGDQLEIQLTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCA
Sbjct: 781 APSDSSGINLSGFGGDQLEIQLTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCA 840
Query: 841 KLMLRTGLLMKLLSEQQEAKALNVEWDTDQQKTNYINENMEQNEQKEQKSSELMKEVPGD 900
KLMLRTGLLMKLLSEQQEAKALNVEWDTDQQKTNYINENMEQNEQKEQKSSELMKEVPGD
Sbjct: 841 KLMLRTGLLMKLLSEQQEAKALNVEWDTDQQKTNYINENMEQNEQKEQKSSELMKEVPGD 900
Query: 901 DYKNKLIFAISVTVILIILIIIFCLIEVNSHKRASEKYKDNPSISGA 947
DYKNKLIFAISVTVILIILIIIFCLIEVNSHKRASEKYKDNPSISGA
Sbjct: 901 DYKNKLIFAISVTVILIILIIIFCLIEVNSHKRASEKYKDNPSISGA 947
>gi|239740955 PREDICTED: similar to c114 SLIT-like testicular protein
isoform 1 [Homo sapiens]
Length = 1635
Score = 759 bits (1960), Expect = 0.0
Identities = 415/668 (62%), Positives = 471/668 (70%), Gaps = 101/668 (15%)
Query: 246 DEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQ------------ 293
+E P P +Q E +++P+T E+ +SS +EAPAQ + P
Sbjct: 488 NENPSPTQQ--------EAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHL 539
Query: 294 --------------------EVEPS-TQQEAPALPPESSMESLAQTPLNHEVTVQPPGED 332
EVE S T +E P PP+ + L + VT PG+D
Sbjct: 540 TQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLR---VYQGVTNPTPGQD 596
Query: 333 QAHYNL-PKFTVKPADVEVTMTSEPKNET-----------------------ESTQAQQE 368
QA + + P TV+ D+ +T+T EP E + Q Q
Sbjct: 597 QAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHS 656
Query: 369 ----APIQPPE-----------EAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTE 413
A +QP + E EPS TAL TT PPP HPEVTLPPSDKGQAQHSHLT+
Sbjct: 657 HLTRATVQPLDLGFTITPKSMTEVEPS-TALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQ 715
Query: 414 ATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAP 473
ATVQPLDLEL+ITT+PTTEVKPSPTTEETS QPPD GLAI PEPTTE GHSTALEKT AP
Sbjct: 716 ATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAP 775
Query: 474 HPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSE--------TAPEEQKASTSTNICELCT 525
PD+VQTLHRSLTEVTGPPT+LE +QDSLVQSE TAPEE KASTSTNICELCT
Sbjct: 776 RPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCT 835
Query: 526 CGDETLSCVGLSPKQRLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLI 585
CGDE LSC+ L+P+QRLRQVPVPEP+T+NG FT LNFQGNYISY+DGNVWKAYSWTEKLI
Sbjct: 836 CGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLI 895
Query: 586 LSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLG 645
L EN LTEL KDSFEGLL LQYLDLSCNKI+ IER TFE LPFL++INL CN+IT+LS G
Sbjct: 896 LRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFG 955
Query: 646 TFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILTMTVEL 705
TFQAWHGMQFLH LILN NPLTTVEDPYLF+LPALKYLDMGTT + LTTLKNIL MTVEL
Sbjct: 956 TFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVEL 1015
Query: 706 EKLILPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEEASVGNPEGAFMKMLQ 765
EKLILPSHMACCLCQFKNSIEAVCKTVKLHCN+ACLTN+IHCPEEASVGNPEGAFMK+LQ
Sbjct: 1016 EKLILPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTIHCPEEASVGNPEGAFMKVLQ 1075
Query: 766 ARKQHMSTQLTIESEAPSDSSGINLSGFGGDQL----EIQLTEQLRSLIP-----NEDVR 816
ARK + ST+L +E E PSDSSGINLSGFG +QL E LR ++P N DV+
Sbjct: 1076 ARKNYTSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLRYILPYFSAVNLDVK 1135
Query: 817 KFMSHVIR 824
+ +I+
Sbjct: 1136 SLLLPLIK 1143
Score = 487 bits (1253), Expect = e-137
Identities = 303/632 (47%), Positives = 349/632 (55%), Gaps = 132/632 (20%)
Query: 1 MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSSRSSHLPWESP 60
MS LRFWGPWPLL WQLL LLVKEAQPL WVKDPLQLTSNPLGPPEPWSS SSH P ESP
Sbjct: 13 MSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESP 72
Query: 61 HAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQD 120
HAP PA P DFD+LGPSASS+M A PQE TENL PFL DSAGELPL PE FLA+ QD
Sbjct: 73 HAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQD 132
Query: 121 LNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVS 180
L DK +P+ERLP L +D P +W
Sbjct: 133 LKDKLSPQERLPVSPKKLKKD--------PAQRW-------------------------- 158
Query: 181 RPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPE 240
SL EI+GI QLS PQ QKQTL ++Y S DT YPGSLPPE
Sbjct: 159 --------------------SLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE 198
Query: 241 LRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQ 300
LRV +DEPPGP EQVG SQFHLEP++QNPETLEDIQSSSLQ+EAPAQL QL +E S Q
Sbjct: 199 LRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQ 258
Query: 301 QEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNET 360
QEAPALPPESSMESL T NHEV+VQPPGEDQA+Y+LP TVKPADVEVT+TSEP NET
Sbjct: 259 QEAPALPPESSMESL--TLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNET 316
Query: 361 ESTQAQQEAPIQPPEEAEPSS--------------------------------------- 381
ES+QAQQE PIQ PEE EPS+
Sbjct: 317 ESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESS 376
Query: 382 -TALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTE 440
T T PPEH EVT+ P Q H +V+P D++L+I EP+ EV S +
Sbjct: 377 PTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQ 436
Query: 441 ETS---------AQPP---DPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTE- 487
E + +PP G + PE + E G ++T P+ + + S T+
Sbjct: 437 EATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQ 496
Query: 488 --VTGPPTKLESSQDSLVQSE-------------TAPEEQKASTSTNICEL---CTCGDE 529
P E + SL E P E T + L T E
Sbjct: 497 EAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPE 556
Query: 530 TLSCVGLSP--KQRLRQVP---VPEPDTYNGI 556
+ + V LSP K+ Q P VP+ Y G+
Sbjct: 557 SKTEVELSPTMKETPTQPPKKVVPQLRVYQGV 588
Score = 176 bits (447), Expect = 7e-44
Identities = 99/197 (50%), Positives = 126/197 (63%), Gaps = 1/197 (0%)
Query: 742 TNSIHCPEEASVGNPEGAFMKMLQARKQHMSTQLTIESEAPSDSSGINLSGFGGDQLEIQ 801
TN H PE S G + Q + + + S L GDQ EIQ
Sbjct: 1417 TNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDPSPEPKSFNYPLLSSPGDQFEIQ 1476
Query: 802 LTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCAKLMLRTGLLMKLLSEQQEAKA 861
LT+QL+SLIPN +VR+ ++HVIRTLKM+CS HVQ +CAKL+ RTG LMKLLS QQE KA
Sbjct: 1477 LTQQLQSLIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKA 1536
Query: 862 LNVEWDTDQQK-TNYINENMEQNEQKEQKSSELMKEVPGDDYKNKLIFAISVTVILIILI 920
+EWDTDQ K NYINE+ E ++++KS EL KEVPG Y +KLI A+ VT IL ILI
Sbjct: 1537 SKIEWDTDQWKIENYINESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVTGILTILI 1596
Query: 921 IIFCLIEVNSHKRASEK 937
I+FCLI + H+R+ ++
Sbjct: 1597 ILFCLIVICCHRRSLQE 1613
>gi|239740953 PREDICTED: similar to c114 SLIT-like testicular protein
isoform 2 [Homo sapiens]
Length = 1700
Score = 759 bits (1960), Expect = 0.0
Identities = 415/668 (62%), Positives = 471/668 (70%), Gaps = 101/668 (15%)
Query: 246 DEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQ------------ 293
+E P P +Q E +++P+T E+ +SS +EAPAQ + P
Sbjct: 488 NENPSPTQQ--------EAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHL 539
Query: 294 --------------------EVEPS-TQQEAPALPPESSMESLAQTPLNHEVTVQPPGED 332
EVE S T +E P PP+ + L + VT PG+D
Sbjct: 540 TQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLR---VYQGVTNPTPGQD 596
Query: 333 QAHYNL-PKFTVKPADVEVTMTSEPKNET-----------------------ESTQAQQE 368
QA + + P TV+ D+ +T+T EP E + Q Q
Sbjct: 597 QAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHS 656
Query: 369 ----APIQPPE-----------EAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTE 413
A +QP + E EPS TAL TT PPP HPEVTLPPSDKGQAQHSHLT+
Sbjct: 657 HLTRATVQPLDLGFTITPKSMTEVEPS-TALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQ 715
Query: 414 ATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAP 473
ATVQPLDLEL+ITT+PTTEVKPSPTTEETS QPPD GLAI PEPTTE GHSTALEKT AP
Sbjct: 716 ATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAP 775
Query: 474 HPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSE--------TAPEEQKASTSTNICELCT 525
PD+VQTLHRSLTEVTGPPT+LE +QDSLVQSE TAPEE KASTSTNICELCT
Sbjct: 776 RPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCT 835
Query: 526 CGDETLSCVGLSPKQRLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLI 585
CGDE LSC+ L+P+QRLRQVPVPEP+T+NG FT LNFQGNYISY+DGNVWKAYSWTEKLI
Sbjct: 836 CGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLI 895
Query: 586 LSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLG 645
L EN LTEL KDSFEGLL LQYLDLSCNKI+ IER TFE LPFL++INL CN+IT+LS G
Sbjct: 896 LRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFG 955
Query: 646 TFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILTMTVEL 705
TFQAWHGMQFLH LILN NPLTTVEDPYLF+LPALKYLDMGTT + LTTLKNIL MTVEL
Sbjct: 956 TFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVEL 1015
Query: 706 EKLILPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEEASVGNPEGAFMKMLQ 765
EKLILPSHMACCLCQFKNSIEAVCKTVKLHCN+ACLTN+IHCPEEASVGNPEGAFMK+LQ
Sbjct: 1016 EKLILPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTIHCPEEASVGNPEGAFMKVLQ 1075
Query: 766 ARKQHMSTQLTIESEAPSDSSGINLSGFGGDQL----EIQLTEQLRSLIP-----NEDVR 816
ARK + ST+L +E E PSDSSGINLSGFG +QL E LR ++P N DV+
Sbjct: 1076 ARKNYTSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLRYILPYFSAVNLDVK 1135
Query: 817 KFMSHVIR 824
+ +I+
Sbjct: 1136 SLLLPLIK 1143
Score = 487 bits (1253), Expect = e-137
Identities = 303/632 (47%), Positives = 349/632 (55%), Gaps = 132/632 (20%)
Query: 1 MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSSRSSHLPWESP 60
MS LRFWGPWPLL WQLL LLVKEAQPL WVKDPLQLTSNPLGPPEPWSS SSH P ESP
Sbjct: 13 MSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESP 72
Query: 61 HAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQD 120
HAP PA P DFD+LGPSASS+M A PQE TENL PFL DSAGELPL PE FLA+ QD
Sbjct: 73 HAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQD 132
Query: 121 LNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVS 180
L DK +P+ERLP L +D P +W
Sbjct: 133 LKDKLSPQERLPVSPKKLKKD--------PAQRW-------------------------- 158
Query: 181 RPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPE 240
SL EI+GI QLS PQ QKQTL ++Y S DT YPGSLPPE
Sbjct: 159 --------------------SLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE 198
Query: 241 LRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQ 300
LRV +DEPPGP EQVG SQFHLEP++QNPETLEDIQSSSLQ+EAPAQL QL +E S Q
Sbjct: 199 LRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQ 258
Query: 301 QEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNET 360
QEAPALPPESSMESL T NHEV+VQPPGEDQA+Y+LP TVKPADVEVT+TSEP NET
Sbjct: 259 QEAPALPPESSMESL--TLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNET 316
Query: 361 ESTQAQQEAPIQPPEEAEPSS--------------------------------------- 381
ES+QAQQE PIQ PEE EPS+
Sbjct: 317 ESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESS 376
Query: 382 -TALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTE 440
T T PPEH EVT+ P Q H +V+P D++L+I EP+ EV S +
Sbjct: 377 PTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQ 436
Query: 441 ETS---------AQPP---DPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTE- 487
E + +PP G + PE + E G ++T P+ + + S T+
Sbjct: 437 EATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQ 496
Query: 488 --VTGPPTKLESSQDSLVQSE-------------TAPEEQKASTSTNICEL---CTCGDE 529
P E + SL E P E T + L T E
Sbjct: 497 EAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPE 556
Query: 530 TLSCVGLSP--KQRLRQVP---VPEPDTYNGI 556
+ + V LSP K+ Q P VP+ Y G+
Sbjct: 557 SKTEVELSPTMKETPTQPPKKVVPQLRVYQGV 588
Score = 176 bits (447), Expect = 7e-44
Identities = 99/197 (50%), Positives = 126/197 (63%), Gaps = 1/197 (0%)
Query: 742 TNSIHCPEEASVGNPEGAFMKMLQARKQHMSTQLTIESEAPSDSSGINLSGFGGDQLEIQ 801
TN H PE S G + Q + + + S L GDQ EIQ
Sbjct: 1417 TNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDPSPEPKSFNYPLLSSPGDQFEIQ 1476
Query: 802 LTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCAKLMLRTGLLMKLLSEQQEAKA 861
LT+QL+SLIPN +VR+ ++HVIRTLKM+CS HVQ +CAKL+ RTG LMKLLS QQE KA
Sbjct: 1477 LTQQLQSLIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKA 1536
Query: 862 LNVEWDTDQQK-TNYINENMEQNEQKEQKSSELMKEVPGDDYKNKLIFAISVTVILIILI 920
+EWDTDQ K NYINE+ E ++++KS EL KEVPG Y +KLI A+ VT IL ILI
Sbjct: 1537 SKIEWDTDQWKIENYINESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVTGILTILI 1596
Query: 921 IIFCLIEVNSHKRASEK 937
I+FCLI + H+R+ ++
Sbjct: 1597 ILFCLIVICCHRRSLQE 1613
>gi|110665701 leucine rich repeat containing 37A [Homo sapiens]
Length = 1700
Score = 755 bits (1949), Expect = 0.0
Identities = 406/634 (64%), Positives = 457/634 (72%), Gaps = 92/634 (14%)
Query: 246 DEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQ------------ 293
+E P P +Q E +++P+T E+ +SS +EAPAQ + P
Sbjct: 488 NENPSPTQQ--------EAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHL 539
Query: 294 --------------------EVEPS-TQQEAPALPPESSMESLAQTPLNHEVTVQPPGED 332
EVE S T +E P PP+ + L + VT PG+D
Sbjct: 540 TQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLR---VYQGVTNPTPGQD 596
Query: 333 QAHYNL-PKFTVKPADVEVTMTSEPKNET-----------------------ESTQAQQE 368
QA + + P TV+ D+ +T+T EP E + Q Q
Sbjct: 597 QAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHS 656
Query: 369 ----APIQPPE-----------EAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTE 413
A +QP + E EPS TAL TT PPP HPEVTLPPSDKGQAQHSHLT+
Sbjct: 657 HLTRATVQPLDLGFTITPKSMTEVEPS-TALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQ 715
Query: 414 ATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAP 473
ATVQPLDLEL+ITT+PTTEVKPSPTTEETS QPPD GLAI PEPTTE GHSTALEKT AP
Sbjct: 716 ATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAP 775
Query: 474 HPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSE--------TAPEEQKASTSTNICELCT 525
PD+VQTLHRSLTEVTGPPT+LE +QDSLVQSE TAPEE KASTSTNICELCT
Sbjct: 776 RPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCT 835
Query: 526 CGDETLSCVGLSPKQRLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLI 585
CGDE LSC+ L+P+QRLRQVPVPEP+T+NG FT LNFQGNYISY+DGNVWKAYSWTEKLI
Sbjct: 836 CGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLI 895
Query: 586 LSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLG 645
L EN LTEL KDSFEGLL LQYLDLSCNKI+ IER TFE LPFL++INL CN+IT+LS G
Sbjct: 896 LRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFG 955
Query: 646 TFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILTMTVEL 705
TFQAWHGMQFLH LILN NPLTTVEDPYLF+LPALKYLDMGTT + LTTLKNIL MTVEL
Sbjct: 956 TFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVEL 1015
Query: 706 EKLILPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEEASVGNPEGAFMKMLQ 765
EKLILPSHMACCLCQFKNSIEAVCKTVKLHCN+ACLTN+ HCPEEASVGNPEGAFMK+LQ
Sbjct: 1016 EKLILPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQ 1075
Query: 766 ARKQHMSTQLTIESEAPSDSSGINLSGFGGDQLE 799
ARK + ST+L +E E PSDSSGINLSGFG +QL+
Sbjct: 1076 ARKNYTSTELIVEPEEPSDSSGINLSGFGSEQLD 1109
Score = 483 bits (1242), Expect = e-136
Identities = 301/632 (47%), Positives = 347/632 (54%), Gaps = 132/632 (20%)
Query: 1 MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSSRSSHLPWESP 60
MS LRFWGPWPLL WQLL LLVKEAQPL WVKDPLQLTSNPLGPPE WSS SSH P ESP
Sbjct: 13 MSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESWSSHSSHFPRESP 72
Query: 61 HAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQD 120
HAP PA P DFD+LGPSASS+M A PQE TENL PFL DSAGE PL PE FLA+ QD
Sbjct: 73 HAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQD 132
Query: 121 LNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVS 180
L DK +P+ERLP L +D P +W
Sbjct: 133 LKDKLSPQERLPVSPKKLKKD--------PAQRW-------------------------- 158
Query: 181 RPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPE 240
SL EI+GI QLS PQ QKQTL ++Y S DT YPGSLPPE
Sbjct: 159 --------------------SLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE 198
Query: 241 LRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQ 300
LRV +DEPPGP EQVG SQFHLEP++QNPETLEDIQSSSLQ+EAPAQL QL +E S Q
Sbjct: 199 LRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQ 258
Query: 301 QEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNET 360
QEAPALPPESSMESL T NHEV+VQPPGEDQA+Y+LP TVKPADVEVT+TSEP NET
Sbjct: 259 QEAPALPPESSMESL--TLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNET 316
Query: 361 ESTQAQQEAPIQPPEEAEPSS--------------------------------------- 381
ES+QAQQE PIQ PEE EPS+
Sbjct: 317 ESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESS 376
Query: 382 -TALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTE 440
T T PPEH EVT+ P Q H +V+P D++L+I EP+ EV S +
Sbjct: 377 PTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQ 436
Query: 441 ETS---------AQPP---DPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTE- 487
E + +PP G + PE + E G ++T P+ + + S T+
Sbjct: 437 EATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQ 496
Query: 488 --VTGPPTKLESSQDSLVQSE-------------TAPEEQKASTSTNICEL---CTCGDE 529
P E + SL E P E T + L T E
Sbjct: 497 EAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPE 556
Query: 530 TLSCVGLSP--KQRLRQVP---VPEPDTYNGI 556
+ + V LSP K+ Q P VP+ Y G+
Sbjct: 557 SKTEVELSPTMKETPTQPPKKVVPQLRVYQGV 588
Score = 176 bits (447), Expect = 7e-44
Identities = 101/199 (50%), Positives = 133/199 (66%), Gaps = 5/199 (2%)
Query: 742 TNSIHCPEEASVGNPE--GAFMKMLQARKQHMSTQLTIESEAPSDSSGINLSGFGGDQLE 799
TN H PE S G G +K + + ++ + + E S + + S GDQ E
Sbjct: 1417 TNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSP--GDQFE 1474
Query: 800 IQLTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCAKLMLRTGLLMKLLSEQQEA 859
IQLT+QL+SLIPN +VR+ ++HVIRTLKM+CS HVQ +CAKL+ RTG LMKLLS QQE
Sbjct: 1475 IQLTQQLQSLIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEV 1534
Query: 860 KALNVEWDTDQQK-TNYINENMEQNEQKEQKSSELMKEVPGDDYKNKLIFAISVTVILII 918
KA +EWDTDQ K NYINE+ E ++++KS EL KEVPG Y +KLI A+ VT IL I
Sbjct: 1535 KASKIEWDTDQWKIENYINESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVTGILTI 1594
Query: 919 LIIIFCLIEVNSHKRASEK 937
LII+FCLI + H+R+ ++
Sbjct: 1595 LIILFCLIVICCHRRSLQE 1613
>gi|75677612 leucine rich repeat containing 37, member A3 [Homo
sapiens]
Length = 1634
Score = 753 bits (1943), Expect = 0.0
Identities = 404/614 (65%), Positives = 458/614 (74%), Gaps = 42/614 (6%)
Query: 231 TLYPGSLPP-ELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLL 289
T+ P S+ EL E P P + + Q + NP +D + QLL
Sbjct: 552 TITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLL 611
Query: 290 QLPQEVEPS-TQQEAPALPPESSMESLAQTPLNHEVTVQPPGEDQA-HYNLPKFTVKPAD 347
L + P T + + PP+ ++ S P + EVT+ P + Q H +L + TV+P D
Sbjct: 612 DLGLTITPEPTTEVGHSTPPKRTIVS----PKHPEVTLPHPDQVQTQHSHLTRATVQPLD 667
Query: 348 VEVTMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQ 407
+ T+T PK+ TE EPS TAL TT PPP HPEVTLPPSDKGQAQ
Sbjct: 668 LGFTIT--PKSMTE---------------VEPS-TALMTTAPPPGHPEVTLPPSDKGQAQ 709
Query: 408 HSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTAL 467
HSHLT+ATVQPLDLEL+ITT+PTTEVKPSPTTEETS Q PD GLAI PEPTTE GHSTAL
Sbjct: 710 HSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTAL 769
Query: 468 EKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSE--------TAPEEQKASTSTN 519
EKT AP PD+VQTLHRSLTEVTGPPT+LE +QDSLVQSE TAPEE KASTSTN
Sbjct: 770 EKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTN 829
Query: 520 ICELCTCGDETLSCVGLSPKQRLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYS 579
ICELCTCGDE LSC+ L+P+QRLRQVPVPEP+T+NG FT LNFQGNYISY+DGNVWKAYS
Sbjct: 830 ICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYS 889
Query: 580 WTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLI 639
WTEKLIL EN LTEL KDSFEGLL LQYLDLSCNKI+ IER TFE LPFL++INL CN+I
Sbjct: 890 WTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVI 949
Query: 640 TKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNIL 699
T+LS GTFQAWHGMQFLH LILN NPLTTVEDPYLF+LPALKYLDMGTT + LTTLKNIL
Sbjct: 950 TELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNIL 1009
Query: 700 TMTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEEASVGNPEGA 759
MTVELEKLI+PSHMACCLCQFKNSIEAVCKTVKLHCN+ACLTN+ HCPEEASVGNPEGA
Sbjct: 1010 MMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGA 1069
Query: 760 FMKMLQARKQHMSTQLTIESEAPSDSSGINLSGFGGDQL----EIQLTEQLRSLIP---- 811
FMK+LQARK + ST+L IE E PSDSSGINLSGFG +QL E +T L ++P
Sbjct: 1070 FMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSA 1129
Query: 812 -NEDVRKFMSHVIR 824
N DV+ + I+
Sbjct: 1130 VNLDVKSLLLPFIK 1143
Score = 491 bits (1265), Expect = e-138
Identities = 304/632 (48%), Positives = 351/632 (55%), Gaps = 132/632 (20%)
Query: 1 MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSSRSSHLPWESP 60
MS LRFWGPWPLL WQLL LLVKEAQPL WVKDPLQLTSNPLGPPEPWSS SSH P ESP
Sbjct: 13 MSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESP 72
Query: 61 HAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQD 120
HAP PA P DFD+LGPSASS+M A PQE TENL PFL DSAGELPL PE FLA+ QD
Sbjct: 73 HAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQD 132
Query: 121 LNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVS 180
L DK +P+ERLP L +D P +W
Sbjct: 133 LKDKLSPQERLPVSPKKLKKD--------PAQRW-------------------------- 158
Query: 181 RPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPE 240
SL EI+GI HQLS PQ QKQTL ++Y S DT YPGSLPPE
Sbjct: 159 --------------------SLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE 198
Query: 241 LRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQ 300
LRV +DEPPGP EQVG SQFHLEP++QNPETLEDIQSSSLQ+EAPAQL QL +E S Q
Sbjct: 199 LRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQ 258
Query: 301 QEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNET 360
QEAPALPPESSMESL T NHEV+VQPPGEDQA+Y+LP TVKPADVEVT+TSEP NET
Sbjct: 259 QEAPALPPESSMESL--TLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNET 316
Query: 361 ESTQAQQEAPIQPPEEAEPSS--------------------------------------- 381
ES+QAQQE PIQ PEE EPS+
Sbjct: 317 ESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESS 376
Query: 382 -TALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTE 440
T T PPEH EVT+ P Q H +V+P D++L+I EP+ EV S +
Sbjct: 377 PTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQ 436
Query: 441 ETS---------AQPP---DPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTE- 487
E + +PP G + PE + E G ++T P+ + + S T+
Sbjct: 437 EATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQ 496
Query: 488 --VTGPPTKLESSQDSLVQSE-------------TAPEEQKASTSTNICEL---CTCGDE 529
P E + SL E P E T + L T E
Sbjct: 497 EAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPE 556
Query: 530 TLSCVGLSP--KQRLRQVP---VPEPDTYNGI 556
+++ V LSP K+ Q P VP+ Y G+
Sbjct: 557 SMTEVELSPTMKETPTQPPKKVVPQLRVYQGV 588
Score = 175 bits (443), Expect = 2e-43
Identities = 99/199 (49%), Positives = 132/199 (66%), Gaps = 5/199 (2%)
Query: 742 TNSIHCPEEASVGNPE--GAFMKMLQARKQHMSTQLTIESEAPSDSSGINLSGFGGDQLE 799
TN H PE S G G +K + + ++ + + E S + + S GDQ E
Sbjct: 1417 TNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSP--GDQFE 1474
Query: 800 IQLTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCAKLMLRTGLLMKLLSEQQEA 859
IQLT+QL+S+IPN +VR+ ++HVIRTLKM+CS HVQ +CAKL+ RTG LMKLLS QQE
Sbjct: 1475 IQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEV 1534
Query: 860 KALNVEWDTDQQKT-NYINENMEQNEQKEQKSSELMKEVPGDDYKNKLIFAISVTVILII 918
KA +EWDTDQ KT NYINE+ E ++++KS E KE+PG Y KLI A+ VT IL I
Sbjct: 1535 KASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTI 1594
Query: 919 LIIIFCLIEVNSHKRASEK 937
LII+ CLIE+ H+R+ ++
Sbjct: 1595 LIILLCLIEICCHRRSLQE 1613
>gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]
Length = 1700
Score = 752 bits (1941), Expect = 0.0
Identities = 405/634 (63%), Positives = 456/634 (71%), Gaps = 92/634 (14%)
Query: 246 DEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQ------------ 293
+E P P +Q E +++P+T E+ +SS +EAPAQ + P
Sbjct: 488 NENPSPTQQ--------EAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHL 539
Query: 294 --------------------EVEPS-TQQEAPALPPESSMESLAQTPLNHEVTVQPPGED 332
EVE S T +E P PP+ + L + VT PG+D
Sbjct: 540 TQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLR---VYQGVTNPTPGQD 596
Query: 333 QAHYNL-PKFTVKPADVEVTMTSEPKNET-----------------------ESTQAQQE 368
QA + + P TV+ D+ +T+T EP E + Q Q
Sbjct: 597 QAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHS 656
Query: 369 ----APIQPPE-----------EAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTE 413
A +QP + E EPS TAL TT PPP HPEVTLPPSDKGQAQHSHLT+
Sbjct: 657 HLTRATVQPLDLGFTITPKSMTEVEPS-TALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQ 715
Query: 414 ATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAP 473
ATVQPLDLEL+ITT+PTTEVKPSPTTEETS QPPD GLAI PEPTTE HSTALEKT AP
Sbjct: 716 ATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAP 775
Query: 474 HPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSE--------TAPEEQKASTSTNICELCT 525
PD+VQTLHRSLTEVTGPPT+LE +QDSLVQSE TAPEE KASTSTNICELCT
Sbjct: 776 RPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCT 835
Query: 526 CGDETLSCVGLSPKQRLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLI 585
CGDE LSC+ L+P+QRLRQVPVPEP+T+NG FT LNFQGNYISY+DGNVWKAYSWTEKLI
Sbjct: 836 CGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLI 895
Query: 586 LSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLG 645
L EN LTEL KDSFEGLL LQYLDLSCNKI+ IER TFE LPFL++INL CN+IT+LS G
Sbjct: 896 LRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFG 955
Query: 646 TFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILTMTVEL 705
TFQAWHGMQFLH LILN NPLTTVEDPYLF+LPALKYLDMGTT + LTTLKNIL MTVEL
Sbjct: 956 TFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVEL 1015
Query: 706 EKLILPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEEASVGNPEGAFMKMLQ 765
EKLILPSHMACCLCQFKNSIEAVCKTVKLHCN+ACLTN+ HCPEEASVGNPEGAFMK+LQ
Sbjct: 1016 EKLILPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQ 1075
Query: 766 ARKQHMSTQLTIESEAPSDSSGINLSGFGGDQLE 799
ARK + ST+L +E E PSDSSGINLSGFG +QL+
Sbjct: 1076 ARKNYTSTELIVEPEEPSDSSGINLSGFGSEQLD 1109
Score = 481 bits (1239), Expect = e-135
Identities = 300/632 (47%), Positives = 347/632 (54%), Gaps = 132/632 (20%)
Query: 1 MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSSRSSHLPWESP 60
MS LRFWGPWPLL WQLL LLVKEAQPL WVKDPLQLTSNPLGPP+ WSS SSH P ESP
Sbjct: 13 MSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPDSWSSHSSHFPRESP 72
Query: 61 HAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQD 120
HAP PA P DFD+LGPSASS+M A PQE TENL PFL DSAGE PL PE FLA+ QD
Sbjct: 73 HAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQD 132
Query: 121 LNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVS 180
L DK +P+ERLP L +D P +W
Sbjct: 133 LKDKLSPQERLPVSPKKLKKD--------PAQRW-------------------------- 158
Query: 181 RPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPE 240
SL EI+GI QLS PQ QKQTL ++Y S DT YPGSLPPE
Sbjct: 159 --------------------SLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE 198
Query: 241 LRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQ 300
LRV +DEPPGP EQVG SQFHLEP++QNPETLEDIQSSSLQ+EAPAQL QL +E S Q
Sbjct: 199 LRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQ 258
Query: 301 QEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNET 360
QEAPALPPESSMESL T NHEV+VQPPGEDQA+Y+LP TVKPADVEVT+TSEP NET
Sbjct: 259 QEAPALPPESSMESL--TLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNET 316
Query: 361 ESTQAQQEAPIQPPEEAEPSS--------------------------------------- 381
ES+QAQQE PIQ PEE EPS+
Sbjct: 317 ESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESS 376
Query: 382 -TALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTE 440
T T PPEH EVT+ P Q H +V+P D++L+I EP+ EV S +
Sbjct: 377 PTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQ 436
Query: 441 ETS---------AQPP---DPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTE- 487
E + +PP G + PE + E G ++T P+ + + S T+
Sbjct: 437 EATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQ 496
Query: 488 --VTGPPTKLESSQDSLVQSE-------------TAPEEQKASTSTNICEL---CTCGDE 529
P E + SL E P E T + L T E
Sbjct: 497 EAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPE 556
Query: 530 TLSCVGLSP--KQRLRQVP---VPEPDTYNGI 556
+ + V LSP K+ Q P VP+ Y G+
Sbjct: 557 SKTEVELSPTMKETPTQPPKKVVPQLRVYQGV 588
Score = 173 bits (438), Expect = 8e-43
Identities = 89/144 (61%), Positives = 112/144 (77%), Gaps = 1/144 (0%)
Query: 795 GDQLEIQLTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCAKLMLRTGLLMKLLS 854
GDQ EIQLT+QL+SLIPN +VR+ ++HVIRTLKM+CS HVQ +CAKL+ RTG LMKLLS
Sbjct: 1470 GDQFEIQLTQQLQSLIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLISRTGHLMKLLS 1529
Query: 855 EQQEAKALNVEWDTDQQK-TNYINENMEQNEQKEQKSSELMKEVPGDDYKNKLIFAISVT 913
QQE KA +EWDTDQ K NYINE+ E ++++KS EL KEVPG Y +KLI A+ VT
Sbjct: 1530 GQQEVKASKIEWDTDQWKIENYINESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVT 1589
Query: 914 VILIILIIIFCLIEVNSHKRASEK 937
IL ILII+FCLI + H+R+ ++
Sbjct: 1590 GILTILIILFCLIVICCHRRSLQE 1613
>gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo
sapiens]
Length = 870
Score = 484 bits (1245), Expect = e-136
Identities = 301/632 (47%), Positives = 348/632 (55%), Gaps = 132/632 (20%)
Query: 1 MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSSRSSHLPWESP 60
MS LRFWGPWPLL WQLL LLVKEAQPL WVKDPLQLTSNPLGPPE WSS SSH P ESP
Sbjct: 13 MSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESWSSHSSHFPRESP 72
Query: 61 HAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQD 120
HAP PA P DFD+LGPSASS+M A PQE TENL PFL DSAGE PL PE FLA+ QD
Sbjct: 73 HAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQD 132
Query: 121 LNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVS 180
L DK +P+ERLP L +D P +W
Sbjct: 133 LKDKLSPQERLPVSPKKLKKD--------PAQRW-------------------------- 158
Query: 181 RPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPE 240
SL EI+GI QLS PQ QKQTL ++Y S DT YP SLPPE
Sbjct: 159 --------------------SLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYPSSLPPE 198
Query: 241 LRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQ 300
LRV +DEPPGP EQVG SQFHLEP++QNPETLEDIQSSSLQ+EAPAQL QL +E S Q
Sbjct: 199 LRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQ 258
Query: 301 QEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNET 360
QEAPALPPESSMESL T NHEV+VQPPGEDQA+Y+LP TVKPADVEVT+TSEP NET
Sbjct: 259 QEAPALPPESSMESL--TLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNET 316
Query: 361 ESTQAQQEAPIQPPEEAEPSS--------------------------------------- 381
ES+QAQQE PIQ PEE EPS+
Sbjct: 317 ESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESS 376
Query: 382 -TALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTE 440
T T PPEH EVT+ P Q H +V+P D++L+I EP+ EV S +
Sbjct: 377 LTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQ 436
Query: 441 ETSA---------QPP---DPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTE- 487
E +A +PP G + PE + E G ++T P+ + + S T+
Sbjct: 437 EATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQ 496
Query: 488 --VTGPPTKLESSQDSLVQSE-------------TAPEEQKASTSTNICEL---CTCGDE 529
P E + SL E P E T + L T E
Sbjct: 497 EAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPE 556
Query: 530 TLSCVGLSP--KQRLRQVP---VPEPDTYNGI 556
+++ V LSP K+ Q P VP+ Y G+
Sbjct: 557 SMTEVELSPTMKETPTQPPKKVVPQLRVYQGV 588
Score = 343 bits (879), Expect = 6e-94
Identities = 238/592 (40%), Positives = 299/592 (50%), Gaps = 106/592 (17%)
Query: 61 HAPAPPAAPGDFDYL---GPSASSQMSALPQEPT----ENLAPFLKELDSAGELPLGPEP 113
H P P D + P+ ++ S QE E + P + ++ E P+ P
Sbjct: 293 HLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPME 352
Query: 114 FLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILV 173
+ + P E EV L + + Q P V + H D V
Sbjct: 353 HELSISEQQQPVQPSESSREVESSLTQQETPG--QPPEHHEVTVSPPGHHQTHHLDSPSV 410
Query: 174 PLDSKVSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLY 233
+ + T + L + + + G + + P Q P S +
Sbjct: 411 SVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAG 470
Query: 234 PGSLPPELRVNADEP-----PGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQL 288
P ++ E + EP P P +Q E +++P+T E+ +SS +EAPAQ
Sbjct: 471 PLAVQQETSFQSPEPINNENPSPTQQ--------EAAAEHPQTAEEGESSLTHQEAPAQT 522
Query: 289 LQLPQ--------------------------------EVEPS-TQQEAPALPPESSMESL 315
+ P EVE S T +E P PP+ + L
Sbjct: 523 PEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQL 582
Query: 316 AQTPLNHEVTVQPPGEDQAHYNL-PKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQP- 373
+ VT PG+DQA + + P TV+ D+ +T+T EP E + A + + P
Sbjct: 583 R---VYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPK 639
Query: 374 -PE------------------------------------EAEPSSTALRTTDPPPEHPEV 396
PE E EPS TAL TT PPP HPEV
Sbjct: 640 HPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPS-TALMTTAPPPGHPEV 698
Query: 397 TLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPE 456
TLPPSDKGQAQHSHLT+ATVQPLDLEL+ITT+PTTEVKPSPTTEETS QPPD GLAI PE
Sbjct: 699 TLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPE 758
Query: 457 PTTEIGHSTALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSE--------TA 508
PTTE GHSTALEKT APHPD+VQ+LHRSLTEVTGPPT+LE +QDSLVQSE TA
Sbjct: 759 PTTETGHSTALEKTTAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTA 818
Query: 509 PEEQKASTSTNICELCTCGDETLSCVGLSPKQRLRQVPVPEPDTYNGIFTTL 560
PEEQKASTSTNICELCTCGDE LSC+ L+P+QRLRQVPVPEP+T+NG FT L
Sbjct: 819 PEEQKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 67.4 bits (163), Expect = 6e-11
Identities = 82/345 (23%), Positives = 124/345 (35%), Gaps = 43/345 (12%)
Query: 212 LSKPQRQKQTLPDDYLSMDTLYPGSLP----PE---LRVNADEPP--GPPEQVGLSQFHL 262
LS P + T P S + P LP PE L +E P PPE+ LS
Sbjct: 449 LSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSP--- 505
Query: 263 EPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQ------QEAPALPPESSMESLA 316
P+S LE+ S +E P+ L+ P P +E+P PP E L
Sbjct: 506 PPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPP---EELP 562
Query: 317 QTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEE 376
+P + PP E+ P+ + E + P E+ + +E+P+ PP E
Sbjct: 563 TSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622
Query: 377 AEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTE-----PTT 431
A S PPPE ++ PP + + ++ + P+ LS E P
Sbjct: 623 ASRLS-------PPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPP 675
Query: 432 EVKP----------SPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTL 481
E P SP E++ PP +P P + E P P++ Q
Sbjct: 676 EESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLC 735
Query: 482 HRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTSTNICELCTC 526
RS P + + +P+ ++ S E C C
Sbjct: 736 PRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLC 780
Score = 62.0 bits (149), Expect = 3e-09
Identities = 116/475 (24%), Positives = 170/475 (35%), Gaps = 68/475 (14%)
Query: 40 NPLGPPEPWSSRSSHLPWESPHAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLK 99
+PL PP P +SR S P +SP +P P +P P S++S LP L+P
Sbjct: 615 SPLSPP-PEASRLSPPPEDSPMSPPPEESP----MSPPPEVSRLSPLP--VVSRLSP--- 664
Query: 100 ELDSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTD 159
E PL P P + +P PE L ++ P
Sbjct: 665 ---PPEESPLSPPP----------EESPTSPPPEASRLSPPPEDSPTSPPPE-------- 703
Query: 160 LDRAAGHQADEILVPLDSKVS----RPTKFVVSPKNLKKDLAERWSLPEIVGIPHQ--LS 213
D A ++ L+ L + S P + + P++ L+ R P + P + LS
Sbjct: 704 -DSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLS 762
Query: 214 KPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLE 273
+ P P P L A+ P P+ + HL P+++ P L
Sbjct: 763 PQAEEPHLSPQPEEPCLCAVPEE--PHLSPQAEGPHLSPQP---EELHLSPQTEEPH-LS 816
Query: 274 DIQSSSLQEEAPAQLLQLPQEVEP--STQQEAPALPPESSMESLAQTPLNHEVTVQPPGE 331
+ P + PQ EP S + E L PE L+ P E + PG+
Sbjct: 817 PVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRP---EKPPEEPGQ 873
Query: 332 DQAHYNLPKFTVKPADVEVTMTSEP----KNETESTQAQQEAPIQPPEEAEPS-STALRT 386
A LP F + EP E + +E P+ P EPS S L
Sbjct: 874 CPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSP--SGEPSLSPQLMP 931
Query: 387 TD--PPPEHPEVT--LPP--SDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTE 440
D PPP P +T PP S G+ ++ + P S P E SP E
Sbjct: 932 PDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDP----ESPLAAPILETPISPPPE 987
Query: 441 ETSAQP-PDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTEVTGPPTK 494
P P P + + P P + +G ++ + P P L SL PP++
Sbjct: 988 ANCTDPEPVPPMILPPSPGSPVGPASPILMEPLP-PQCSPLLQHSLVPQNSPPSQ 1041
Score = 60.8 bits (146), Expect = 6e-09
Identities = 120/462 (25%), Positives = 170/462 (36%), Gaps = 75/462 (16%)
Query: 40 NPLGPPEPWSSRSSHLPWESPHAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLK 99
+P PP P +SR S P E P +P P A P S +S P+E + P
Sbjct: 456 SPTSPP-PEASRLSPPPEELPASPLPEA----LHLSRPLEESPLSPPPEESPLSPPPESS 510
Query: 100 ELDSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTD 159
E PL P L TP PE PL + L P +
Sbjct: 511 PFSPLEESPLSPPEESPPSPAL---ETPLSPPPEASPLSPPFEESPLSPPPE-------E 560
Query: 160 LDRAAGHQADEILVPLDSKVSR--PTKFVVSPKNLKKDLAERWSLPEIVGIPHQ--LSKP 215
L + +A + P + P + +SP L + + P + LS P
Sbjct: 561 LPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPP 620
Query: 216 QRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVG-LSQFHLEPKSQNPETLED 274
+ P S P S PPE + P PP +V LS + + P E+
Sbjct: 621 PEASRLSPPPEDS-----PMSPPPE-----ESPMSPPPEVSRLSPLPVVSRLSPPP--EE 668
Query: 275 IQSSSLQEEAP------AQLLQLPQEVEPST--QQEAPALPPESSMESLAQTPLNHEVTV 326
S EE+P A L P E P++ +++PA PP +SL PL +
Sbjct: 669 SPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPE--DSLMSLPLEESPLL 726
Query: 327 QPPGEDQ--AHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEAEPSSTAL 384
P E Q P + +P + ++ P+ E Q E P P+ EP A+
Sbjct: 727 PLPEEPQLCPRSEGPHLSPRPEEPHLS----PRPEEPHLSPQAEEPHLSPQPEEPCLCAV 782
Query: 385 RTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTE-----PTTE---VKPS 436
PE P ++ QA+ HL+ QP +L LS TE P E + P
Sbjct: 783 ------PEEPHLS------PQAEGPHLSP---QPEELHLSPQTEEPHLSPVPEEPCLSPQ 827
Query: 437 PTTEETSAQPPDPGLAITPEPTTEIGHSTALEK-TRAPHPDQ 477
P S Q +P L+ PE E S LEK +P P++
Sbjct: 828 PEESHLSPQSEEPCLSPRPE---ESHLSPELEKPPLSPRPEK 866
Score = 60.1 bits (144), Expect = 1e-08
Identities = 59/233 (25%), Positives = 94/233 (40%), Gaps = 31/233 (13%)
Query: 252 PEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQE--VEPSTQQEAPALPPE 309
P++ G Q +P + LE + L EE P LL P+E + P ++ + PPE
Sbjct: 406 PKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMP--LLPPPEESPLSPPPEESPTSPPPE 463
Query: 310 SSM-----ESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQ 364
+S E L +PL + + P E+ + P E ++ P E+
Sbjct: 464 ASRLSPPPEELPASPLPEALHLSRPLEES--------PLSPPPEESPLSPPP--ESSPFS 513
Query: 365 AQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELS 424
+E+P+ PPEE+ PS PPPE ++ P E+ + P EL
Sbjct: 514 PLEESPLSPPEESPPSPALETPLSPPPEASPLSPP-----------FEESPLSPPPEELP 562
Query: 425 ITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQ 477
T+ P + SP EE+ PP ++P P E +P P++
Sbjct: 563 -TSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEE 614
Score = 48.5 bits (114), Expect = 3e-05
Identities = 99/431 (22%), Positives = 145/431 (33%), Gaps = 44/431 (10%)
Query: 38 TSNPLGPPEPWSSRSSHL-PWESPHAPAPPAAPGDFDYLGPSASSQMSAL-PQEPTENLA 95
+ +PLGP + S L P P PPA G YL AS + P E E+
Sbjct: 2590 SGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPG 2649
Query: 96 PFLKELDSAGELPLGPEPFLAA-HQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKW 154
+ + ELP +P ++ Q +K+ +RL E LL R Q Q
Sbjct: 2650 TGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRE---LLIRQQIQ---------- 2696
Query: 155 VQTTDLDRAAGHQADEILVPLDSKVSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSK 214
R Q E V P + P + + R P G ++
Sbjct: 2697 -------RNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTP-FAG-----TQ 2743
Query: 215 PQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLED 274
+ LP LS L PGS P + R++ PP P + ++ L SQ
Sbjct: 2744 DKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAP 2803
Query: 275 IQSSSLQEEAPAQLLQLPQEVEPSTQQEA-----PALP-PESSMESLAQTPLNHEVTVQP 328
S ++ QL Q Q ++ + A P+ P PE ++L +
Sbjct: 2804 YPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPG 2863
Query: 329 PGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEAEPSSTA----- 383
PGE P ++ V P Q + P P +P A
Sbjct: 2864 PGEPVPGPAGPAQFIELRH-NVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLR 2922
Query: 384 -LRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEV-KPSPTTEE 441
L + PP+ P P + T+ P LEL +TE+ +P+P E
Sbjct: 2923 GLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALE 2982
Query: 442 TSAQP-PDPGL 451
P DP L
Sbjct: 2983 AGKLPCEDPEL 2993
Score = 37.0 bits (84), Expect = 0.087
Identities = 111/512 (21%), Positives = 175/512 (34%), Gaps = 89/512 (17%)
Query: 41 PLGPPEPWSSRSSHLPWESPHAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKE 100
P P PW+ +P P P G+ D L + +Q S E E L +
Sbjct: 1966 PGEPDSPWTGSGG----TTPSTPTTPTTEGEGDGL---SYNQRSLQRWEKDEELG----Q 2014
Query: 101 LDSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDL 160
L + + F QD D + R +++ L + A + P L+ +
Sbjct: 2015 LSTISPVLYANINFPNLKQDYPDWSS---RCKQIMKLWRKVP--AADKAPYLQKAK---- 2065
Query: 161 DRAAGHQADEILVPLDSKVSRPTKFVVSPKNLKKDLAERWSLPEI-VGIPHQL----SKP 215
D A H+ +++ +S++++ TK D+A + P + + IP Q S P
Sbjct: 2066 DNRAAHRINKVQKQAESQINKQTKV--------GDIARKTDRPALHLRIPPQPGALGSPP 2117
Query: 216 QRQKQTL----PDDYLSMDTLYPGSLPPELRVNADEPPGP--PEQVGLS---QFHLEPKS 266
T+ P + T G L P A PGP P ++ L Q + S
Sbjct: 2118 PAAAPTIFIGSPTTPAGLSTSADGFLKPP----AGSVPGPDSPGELFLKLPPQVPAQVPS 2173
Query: 267 QNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQEAPALPPESSMESLAQTPLNHEVTV 326
Q+P L + L+ P P P+ APA PP S E
Sbjct: 2174 QDPFGLAP--AYPLEPRFPTAPPTYPPYPSPTG---APAQPPMLGASSRPGAGQPGEFHT 2228
Query: 327 QPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPP------EEAEPS 380
PPG + + P +KP + + P++ E + PP + E
Sbjct: 2229 TPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVK 2288
Query: 381 STALRTTDP---PPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSP 437
L + P PP V P S +HL ++ D+ + T ++V+P
Sbjct: 2289 KEELGASSPSYGPPNLGFVDSPSSG------THLGGLELKTPDVFKAPLTPRASQVEPQS 2342
Query: 438 TTEETSAQPPDPGLAITPEP------------TTEIGHSTALEKTRAPHPDQVQTLHRSL 485
Q P P A+ P P T + + P P+ L
Sbjct: 2343 PGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCAL---- 2398
Query: 486 TEVTGPPTKLESSQDSLVQSETAPEEQKASTS 517
PP L S S V + +P+ Q +S S
Sbjct: 2399 -----PPRSLPSDPFSRVPA--SPQSQSSSQS 2423
Score = 31.6 bits (70), Expect = 3.7
Identities = 37/160 (23%), Positives = 52/160 (32%), Gaps = 5/160 (3%)
Query: 261 HLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQEAPALPPESSMESLAQTPL 320
HL P+ Q +Q Q +A + Q P EP TQ +P L P
Sbjct: 4213 HLSPQQQQQLQALLMQRQLQQSQA---VRQTPPYQEPGTQT-SPLQGLLGCQPQLGGFPG 4268
Query: 321 NHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEAEPS 380
+Q G P+ P + P + T + QE P +P + PS
Sbjct: 4269 PQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQE-PKRPSQLPSPS 4327
Query: 381 STALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLD 420
S PP HP P + ++ A Q D
Sbjct: 4328 SQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLAD 4367
Score = 31.2 bits (69), Expect = 4.8
Identities = 35/142 (24%), Positives = 50/142 (35%), Gaps = 22/142 (15%)
Query: 368 EAPIQP-PEEAEPSSTAL--RTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELS 424
+AP+ P + EP S L R +PPP PPS + T+ QP
Sbjct: 2328 KAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQP------ 2381
Query: 425 ITTEPTTEVKPSPTTEETSAQPP-----DPGLAITPEPTTEIGHSTALE----KTRAPHP 475
P T P E A PP DP + P ++ + L A P
Sbjct: 2382 ----PLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCP 2437
Query: 476 DQVQTLHRSLTEVTGPPTKLES 497
V +S + PP++ +S
Sbjct: 2438 SPVTPRFQSPDPYSRPPSRPQS 2459
Score = 30.8 bits (68), Expect = 6.2
Identities = 43/188 (22%), Positives = 59/188 (31%), Gaps = 18/188 (9%)
Query: 301 QEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNET 360
Q P LP +L+ P+ V PP P P+ T P
Sbjct: 4284 QGPPRLPAPPG--ALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHP 4341
Query: 361 ESTQAQQEAPIQPPEEAEPSSTALRTT---------DPPPEHPEVTLPPSDKGQAQHSHL 411
+ + Q PP P++ L T DPP E P H
Sbjct: 4342 GTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQ 4401
Query: 412 TEATVQPLDLELSITTEPTTE---VKPSPTTEETSAQP-PDPGLA---ITPEPTTEIGHS 464
V P +LSI EP E + E + +P PG + + P +E GH
Sbjct: 4402 VNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHL 4461
Query: 465 TALEKTRA 472
+ RA
Sbjct: 4462 LLQKLLRA 4469
>gi|27436867 slit and trk like 4 protein [Homo sapiens]
Length = 837
Score = 67.4 bits (163), Expect = 6e-11
Identities = 63/232 (27%), Positives = 104/232 (44%), Gaps = 27/232 (11%)
Query: 517 STNICELCTCGDET----LSCVGLSPKQRLRQVPVPEPDTYNGIFTTLNFQGNYISYLDG 572
S IC +C+C ++C +S R Q+ P + Y+ LNFQ N+++ L
Sbjct: 23 SVEICNVCSCVSVENVLYVNCEKVSV-YRPNQLKPPWSNFYH-----LNFQNNFLNILYP 76
Query: 573 NVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYI 632
N + +S L L N L + +F GL L+ L L+ N+++ + TF + L+Y+
Sbjct: 77 NTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENLEYL 136
Query: 633 NLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITL 692
NLI + G F H ++ LILN N ++ + D +F +L +LD+ I
Sbjct: 137 QADYNLIKYIERGAFNKLHKLKV---LILNDNLISFLPD-NIFRFASLTHLDIRGNRIQK 192
Query: 693 TTLKNILT---MTVELEKLILPSHMACCLCQFKNSI----------EAVCKT 731
+L VEL+ P + +C L K + EA+C+T
Sbjct: 193 LPYIGVLEHIGRVVELQLEDNPWNCSCDLLPLKAWLENMPYNIYIGEAICET 244
Score = 60.5 bits (145), Expect = 7e-09
Identities = 85/332 (25%), Positives = 134/332 (40%), Gaps = 48/332 (14%)
Query: 448 DPGLAITPEPTTEIGHSTALEKTRAPHPDQVQT-LHRSLTEVTGPPTKLESSQDSLVQSE 506
D + I P E G++T P+ QT LHR +T+ PP S+ S + +
Sbjct: 269 DFDVRILPPSQLENGYTT-------PNGHTTQTSLHRLVTK---PPKTTNPSKISGIVAG 318
Query: 507 TAPEE----QKASTSTNICELCTCGDETL-----SCVGLSPKQRLRQVP-----VPEPDT 552
A Q S T + L C S +GLS + + + +P+P
Sbjct: 319 KALSNRNLSQIVSYQTRVPPLTPCPAPCFCKTHPSDLGLSVNCQEKNIQSMSELIPKPLN 378
Query: 553 YNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSC 612
L+ GN I +D + + + + L L N +T + D F L L+ L L+
Sbjct: 379 AK----KLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNG 434
Query: 613 NKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDP 672
N+I + + F L LQY+ L NLI ++S GTF + +Q L+ LN N L ++
Sbjct: 435 NQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLY---LNNNLLKSL-PV 490
Query: 673 YLFELPALKYLDMGTTHITLTTLKNILTMTVELEKLIL---PSHMACCLCQFKNSIEAVC 729
Y+F L L++ + +L L ++ L P C L K +E +
Sbjct: 491 YIFSGAPLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWDCTCDLVALKLWVEKLS 550
Query: 730 KTV---KLHCNT---------ACLTNSIHCPE 749
+ +L C T L N I CP+
Sbjct: 551 DGIVVKELKCETPVQFANIELKSLKNEILCPK 582
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 67.0 bits (162), Expect = 8e-11
Identities = 110/517 (21%), Positives = 190/517 (36%), Gaps = 70/517 (13%)
Query: 22 VKEAQPLVWVKDPLQLTSNPLGPPEP---------WSSRSSHLPWESPHAPAP-PAAPGD 71
+ +P V ++ P T P P E S+ +P E P+ P+ P P +
Sbjct: 565 ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSE 624
Query: 72 FDYL---GPSASSQMSALPQE-----------PTENLAPFLKELDSAGELPLGP--EPFL 115
+ P+ S+ +P E PTE +E ++ E P+ P +P +
Sbjct: 625 KPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSI 684
Query: 116 AAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPL 175
+ P + E + ++ ++ + P + + T + ++ P
Sbjct: 685 PTEKPSIPTEKPTISMEETI--ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPT 742
Query: 176 DSKVSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPG 235
+ K +SP+ + PE + IP + +K T+P + ++ T P
Sbjct: 743 EKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPT 802
Query: 236 SLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEV 295
+ E ++ ++P P E +P ET ++ +++ E L +P E
Sbjct: 803 TPTEETTISTEKPSIPME---------KPTLPTEETTTSVEETTISTEK----LTIPME- 848
Query: 296 EPSTQQEAPALPPESSMESLAQTPLNHEVTVQPPGE-----DQAHYNLPKFTVKPADVEV 350
+P+ E P +P E S + + E P + ++ + K T+ P +
Sbjct: 849 KPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTI-PTEKPT 907
Query: 351 TMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALR-TTDPPPEHPEVTLPPSDKGQAQHS 409
+P TE E P P EE S+ L T+ P PE P++K
Sbjct: 908 ISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTIS-- 965
Query: 410 HLTEATVQPLDLELSITTE-PT--TEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTA 466
TE P + +L+I TE PT TE PT + T+ +PP P T G +
Sbjct: 966 --TEKPTIPTE-KLTIPTEKPTIPTEKPTIPTEKLTALRPPHPS-------PTATGLAAL 1015
Query: 467 LEKTRAPHPDQVQ------TLHRSLTEVTGPPTKLES 497
+ AP T RS TE P + ES
Sbjct: 1016 VMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYES 1052
Score = 51.2 bits (121), Expect = 4e-06
Identities = 65/292 (22%), Positives = 110/292 (37%), Gaps = 16/292 (5%)
Query: 234 PGSLP----PELR-VNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQL 288
PG+ P PEL V+ GP E GL++ + ++E ++ + P +
Sbjct: 531 PGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEK 590
Query: 289 LQLPQEVEPSTQQEAPALPPES-SMESLAQTPLNHEVTV--QPPGEDQAHYNLPKFTVKP 345
+P E +P+ E P +P E +M S T + + T+ + P +P
Sbjct: 591 PTIPTE-KPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTI 649
Query: 346 ADVEVTM-TSEPKNETESTQAQQEAPIQPPEEAE-PSSTALRTTDPPPEHPEVTLPPSDK 403
+ + T+ T EP TE T E P+ P E+ P+ T+ P E T+ ++K
Sbjct: 650 STEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEK 709
Query: 404 GQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGH 463
T T +P +I TE +T PTT P I+PE T
Sbjct: 710 PTISPEKPTIPTEKP-----TIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTE 764
Query: 464 STALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKAS 515
+ + P + T+ + + + + + ET +K S
Sbjct: 765 KPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS 816
Score = 48.5 bits (114), Expect = 3e-05
Identities = 72/354 (20%), Positives = 127/354 (35%), Gaps = 32/354 (9%)
Query: 178 KVSRPTKFVVSPKNLKKDLAERWSLP-EIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGS 236
K + P++ P L E+ ++P E IP + +K T+P + + T +
Sbjct: 611 KPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTT 670
Query: 237 LPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLP---- 292
E + ++P P E+ + +P ET+ + ++ E P + P
Sbjct: 671 SMEEPVIPTEKPSIPTEKPSIPTE--KPTISMEETIISTEKPTISPEKPTIPTEKPTIPT 728
Query: 293 -----QEVEPSTQQEAPALPPESSMESLAQ-TPLNHEVTVQPPGEDQAHYNLPKFTVKPA 346
+P+T E P +P E S + T + T+ P K T+ P
Sbjct: 729 EKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPE----------KLTI-PT 777
Query: 347 DVEVTMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDP--PPEHPEVTLPPSDKG 404
+ T +P TE E P P EE T + T P P E P + +
Sbjct: 778 EKPTIPTEKPTIPTEKPTISTEEPTTPTEE-----TTISTEKPSIPMEKPTLPTEETTTS 832
Query: 405 QAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHS 464
+ + TE P++ + +I+TE T PT P L I E T
Sbjct: 833 VEETTISTEKLTIPME-KPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEE 891
Query: 465 TALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTST 518
T + + P + T+ ++ + + + ++ ET +K + T
Sbjct: 892 TTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPT 945
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 67.0 bits (162), Expect = 8e-11
Identities = 110/517 (21%), Positives = 190/517 (36%), Gaps = 70/517 (13%)
Query: 22 VKEAQPLVWVKDPLQLTSNPLGPPEP---------WSSRSSHLPWESPHAPAP-PAAPGD 71
+ +P V ++ P T P P E S+ +P E P+ P+ P P +
Sbjct: 565 ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSE 624
Query: 72 FDYL---GPSASSQMSALPQE-----------PTENLAPFLKELDSAGELPLGP--EPFL 115
+ P+ S+ +P E PTE +E ++ E P+ P +P +
Sbjct: 625 KPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSI 684
Query: 116 AAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPL 175
+ P + E + ++ ++ + P + + T + ++ P
Sbjct: 685 PTEKPSIPTEKPTISMEETI--ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPT 742
Query: 176 DSKVSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPG 235
+ K +SP+ + PE + IP + +K T+P + ++ T P
Sbjct: 743 EKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPT 802
Query: 236 SLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEV 295
+ E ++ ++P P E +P ET ++ +++ E L +P E
Sbjct: 803 TPTEETTISTEKPSIPME---------KPTLPTEETTTSVEETTISTEK----LTIPME- 848
Query: 296 EPSTQQEAPALPPESSMESLAQTPLNHEVTVQPPGE-----DQAHYNLPKFTVKPADVEV 350
+P+ E P +P E S + + E P + ++ + K T+ P +
Sbjct: 849 KPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTI-PTEKPT 907
Query: 351 TMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALR-TTDPPPEHPEVTLPPSDKGQAQHS 409
+P TE E P P EE S+ L T+ P PE P++K
Sbjct: 908 ISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTIS-- 965
Query: 410 HLTEATVQPLDLELSITTE-PT--TEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTA 466
TE P + +L+I TE PT TE PT + T+ +PP P T G +
Sbjct: 966 --TEKPTIPTE-KLTIPTEKPTIPTEKPTIPTEKLTALRPPHPS-------PTATGLAAL 1015
Query: 467 LEKTRAPHPDQVQ------TLHRSLTEVTGPPTKLES 497
+ AP T RS TE P + ES
Sbjct: 1016 VMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYES 1052
Score = 51.2 bits (121), Expect = 4e-06
Identities = 65/292 (22%), Positives = 110/292 (37%), Gaps = 16/292 (5%)
Query: 234 PGSLP----PELR-VNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQL 288
PG+ P PEL V+ GP E GL++ + ++E ++ + P +
Sbjct: 531 PGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEK 590
Query: 289 LQLPQEVEPSTQQEAPALPPES-SMESLAQTPLNHEVTV--QPPGEDQAHYNLPKFTVKP 345
+P E +P+ E P +P E +M S T + + T+ + P +P
Sbjct: 591 PTIPTE-KPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTI 649
Query: 346 ADVEVTM-TSEPKNETESTQAQQEAPIQPPEEAE-PSSTALRTTDPPPEHPEVTLPPSDK 403
+ + T+ T EP TE T E P+ P E+ P+ T+ P E T+ ++K
Sbjct: 650 STEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEK 709
Query: 404 GQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGH 463
T T +P +I TE +T PTT P I+PE T
Sbjct: 710 PTISPEKPTIPTEKP-----TIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTE 764
Query: 464 STALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKAS 515
+ + P + T+ + + + + + ET +K S
Sbjct: 765 KPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS 816
Score = 48.5 bits (114), Expect = 3e-05
Identities = 72/354 (20%), Positives = 127/354 (35%), Gaps = 32/354 (9%)
Query: 178 KVSRPTKFVVSPKNLKKDLAERWSLP-EIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGS 236
K + P++ P L E+ ++P E IP + +K T+P + + T +
Sbjct: 611 KPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTT 670
Query: 237 LPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLP---- 292
E + ++P P E+ + +P ET+ + ++ E P + P
Sbjct: 671 SMEEPVIPTEKPSIPTEKPSIPTE--KPTISMEETIISTEKPTISPEKPTIPTEKPTIPT 728
Query: 293 -----QEVEPSTQQEAPALPPESSMESLAQ-TPLNHEVTVQPPGEDQAHYNLPKFTVKPA 346
+P+T E P +P E S + T + T+ P K T+ P
Sbjct: 729 EKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPE----------KLTI-PT 777
Query: 347 DVEVTMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDP--PPEHPEVTLPPSDKG 404
+ T +P TE E P P EE T + T P P E P + +
Sbjct: 778 EKPTIPTEKPTIPTEKPTISTEEPTTPTEE-----TTISTEKPSIPMEKPTLPTEETTTS 832
Query: 405 QAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHS 464
+ + TE P++ + +I+TE T PT P L I E T
Sbjct: 833 VEETTISTEKLTIPME-KPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEE 891
Query: 465 TALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTST 518
T + + P + T+ ++ + + + ++ ET +K + T
Sbjct: 892 TTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPT 945
>gi|85986601 relaxin/insulin-like family peptide receptor 1 [Homo
sapiens]
Length = 757
Score = 66.2 bits (160), Expect = 1e-10
Identities = 55/192 (28%), Positives = 90/192 (46%), Gaps = 19/192 (9%)
Query: 524 CTCGDETLSCVGLSPKQRLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEK 583
C C L C + LR VP + + T ++ Q N I L + +K Y +K
Sbjct: 104 CLCQGLELDC----DETNLRAVP-----SVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQK 154
Query: 584 LILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLS 643
L L N +T + +F GL L L LS N+I +++ FE L L+++ + N ++++S
Sbjct: 155 LYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRIS 214
Query: 644 LGTFQAWHGMQFLHNLILNRNPLTTVED-PYLFELPALKYLDMGTTHI------TLTTLK 696
TF +G+ L L+L N LT + D P +P L +LD+ HI T +
Sbjct: 215 PPTF---YGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCS 271
Query: 697 NILTMTVELEKL 708
N+ + + K+
Sbjct: 272 NLTVLVMRKNKI 283
Score = 42.4 bits (98), Expect = 0.002
Identities = 27/88 (30%), Positives = 43/88 (48%)
Query: 560 LNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIE 619
L+ +GN+I L + + S L++ +N + L +++F L L LDL NKI +
Sbjct: 252 LDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLP 311
Query: 620 RQTFESLPFLQYINLGCNLITKLSLGTF 647
F+ L L +NL N I K+ F
Sbjct: 312 PLIFKDLKELSQLNLSYNPIQKIQANQF 339
Score = 34.7 bits (78), Expect = 0.43
Identities = 34/127 (26%), Positives = 54/127 (42%), Gaps = 4/127 (3%)
Query: 560 LNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELP-KDSFEGLLYLQYLDLSCNKIRYI 618
L + N++S + + + L+L N LT LP K + + L +LDL N I +
Sbjct: 203 LIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNL 262
Query: 619 ERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELP 678
TF S L + + N I L+ TF +Q L L L N + + +L
Sbjct: 263 RNLTFISCSNLTVLVMRKNKINHLNENTFAP---LQKLDELDLGSNKIENLPPLIFKDLK 319
Query: 679 ALKYLDM 685
L L++
Sbjct: 320 ELSQLNL 326
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 65.5 bits (158), Expect = 2e-10
Identities = 128/509 (25%), Positives = 167/509 (32%), Gaps = 71/509 (13%)
Query: 43 GPPEPWSSRSSHLPWE-SPHAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKEL 101
GP + SS S H E SP A P+A G S S SA P P +
Sbjct: 204 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA-SRSLSSSATPLSSPARSGPSARGT 262
Query: 102 DSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLD 161
A P P+P K R P+V P +D AL L + T
Sbjct: 263 PRAPAHPSQPKP----------KGLQALRPPQVTPP-RKDAAPALGPLSSSP-LATPSPS 310
Query: 162 RAAGHQADEILVPLDSKVSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQT 221
A QA L P S T + +P L + P + +P + P Q T
Sbjct: 311 AALQSQAPPTL-PATPHSSSLTCQLATPLPLAPPSPS--APPSLQTLPSPPATPPSQATT 367
Query: 222 -------------LPDDYLSMDTLYPGSLPPELRVNA-DEPPGPPEQVGLSQFHLEPKSQ 267
LP LS P PP L + PP PP LS P Q
Sbjct: 368 SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL-ATPSPQ 426
Query: 268 NPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQEAPALPPESSMESLAQTPLNHEVTVQ 327
P L LLQ P PS +AP PP S S + TP + Q
Sbjct: 427 APNALA------------VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS-----Q 469
Query: 328 PPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAP---IQPPEEAEPSSTAL 384
P P P V + + P +T Q P P + A+P A
Sbjct: 470 AP---------PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 520
Query: 385 RTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPL----DLELSITTEPTTEVKPSPTTE 440
PP + P S GQA S + PL + P +V PSP
Sbjct: 521 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 580
Query: 441 ETSAQPPDPGLAITPEPTTEIGH---STALEKTRAPHPDQVQTLHRSLTEVTGPPTKLES 497
T P P TP P T + + AL P P + + S ++ G + S
Sbjct: 581 PTLQAPRRPP---TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS 637
Query: 498 SQDSLVQSETAPEEQKASTSTNICELCTC 526
+ + L ++ PE A++ EL C
Sbjct: 638 TPEELRGYDSGPEGGAAASPPPDAELAAC 666
Score = 47.0 bits (110), Expect = 8e-05
Identities = 97/438 (22%), Positives = 127/438 (28%), Gaps = 68/438 (15%)
Query: 37 LTSNPLGPPEPWSSRSSHLPWESPHAPAPP---------AAPGDFDYLGPSASSQMSALP 87
L+S+PL P P ++ S P P PA P A P PSA + LP
Sbjct: 299 LSSSPLATPSPSAALQSQAP---PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLP 355
Query: 88 QEPTENLAPFLKELDSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALV 147
P P + S G L L+ TP + P + L +
Sbjct: 356 SPPA---TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 412
Query: 148 QLPRLKWVQTTDLDRAAGHQADEILVPLDSKVSRPTKFVVSPKNLKKDLAERWSLPEIVG 207
P L + T + P S P + SP
Sbjct: 413 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP------------------ 454
Query: 208 IPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQ 267
S P T P P P L+V P PP + P++
Sbjct: 455 ---PASPPVSPSATPPSQ------APPSLAAPPLQVPPSPPASPPMSPSATP---PPQAP 502
Query: 268 NPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQEAPALPPESSMESLAQTPLNHEVTVQ 327
P +Q + +AP L P + PS P P S SL +PL
Sbjct: 503 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL-----AT 557
Query: 328 PPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTT 387
PP + P V P S P + T QA + P P+ +
Sbjct: 558 PPPQAPPVLAAPLLQVPP--------SPPASPT--LQAPRRPPTPGPDTSVSGPRLTLAL 607
Query: 388 DPPPEHPEVTLPPSD-KGQAQHSHLTEATVQPLDLE-LSITTEPTTEVKPSPTTEETSAQ 445
P P P P S G H + AT P +L E P P E +
Sbjct: 608 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 667
Query: 446 P------PDPGLAITPEP 457
P P P LA P
Sbjct: 668 PAAWSRGPAPPLAFRGAP 685
>gi|10190722 leucine-rich repeats and transmembrane domains 1 [Homo
sapiens]
Length = 345
Score = 64.7 bits (156), Expect = 4e-10
Identities = 47/166 (28%), Positives = 82/166 (49%), Gaps = 13/166 (7%)
Query: 523 LCTCGDE-----TLSCVGLSPKQRLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKA 577
+C+C D+ + + V S +Q L ++P P TL+ Q N I +L +++
Sbjct: 18 VCSCPDKCYCQSSTNFVDCS-QQGLAEIPSHLPPQTR----TLHLQDNQIHHLPAFAFRS 72
Query: 578 YSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCN 637
W L LS N L+ L +F GL +LQ L+L+ N + +E + F SLP L+ ++L N
Sbjct: 73 VPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNSLLSLESRLFHSLPQLRELDLSSN 132
Query: 638 LITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYL 683
I+ L + W + L + +N L ++ L +P+++ L
Sbjct: 133 NISHLPTSLGETWENLTI---LAVQQNQLQQLDRALLESMPSVRLL 175
Score = 51.6 bits (122), Expect = 3e-06
Identities = 29/84 (34%), Positives = 47/84 (55%), Gaps = 3/84 (3%)
Query: 608 LDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLT 667
L L N+I ++ F S+P+L +NL N ++ L+ G F HG+Q L L L +N L
Sbjct: 55 LHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAF---HGLQHLQVLNLTQNSLL 111
Query: 668 TVEDPYLFELPALKYLDMGTTHIT 691
++E LP L+ LD+ + +I+
Sbjct: 112 SLESRLFHSLPQLRELDLSSNNIS 135
Score = 34.3 bits (77), Expect = 0.57
Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 2/91 (2%)
Query: 550 PDTYNGI--FTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQY 607
P ++G+ LN N + L+ ++ + +L LS N ++ LP E L
Sbjct: 91 PGAFHGLQHLQVLNLTQNSLLSLESRLFHSLPQLRELDLSSNNISHLPTSLGETWENLTI 150
Query: 608 LDLSCNKIRYIERQTFESLPFLQYINLGCNL 638
L + N+++ ++R ES+P ++ + L NL
Sbjct: 151 LAVQQNQLQQLDRALLESMPSVRLLLLKDNL 181
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 63.5 bits (153), Expect = 9e-10
Identities = 117/512 (22%), Positives = 175/512 (34%), Gaps = 72/512 (14%)
Query: 34 PLQLTSNPLGPPEPWSSRSSHLPWESPHAPAPPAAPGDFDYLGPSASSQMSALPQEPTEN 93
P S P P EP + + +P PAP P+ ++ P P E
Sbjct: 405 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK------PAPTTPKEPAPTTPKEP 458
Query: 94 LAPFLKELDSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLK 153
K+ A P P P TP+E P L + L K
Sbjct: 459 APTTTKK--PAPTTPKEPAP-----------TTPKETAPTTPKKLTPTTPEKLAPTTPEK 505
Query: 154 WVQTTDLDRAAGHQADEILVPLDSKVSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLS 213
TT + A E P + PT + N K+ A P + +
Sbjct: 506 PAPTTPEELAP--TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 563
Query: 214 KPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLE 273
P K+T P T G+ P L+ A P P PK P T +
Sbjct: 564 -PTTPKETAP-------TTPKGTAPTTLKEPAPTTPKKPA----------PKELAPTTTK 605
Query: 274 DIQSSSLQEEAPAQLLQLPQEVEPSTQQE-APALPPESSMESLAQTPLNHEVTVQPPGED 332
+ S++ + AP P+ P+T +E AP P E + + T T++ P
Sbjct: 606 EPTSTTCDKPAPTT----PKGTAPTTPKEPAPTTPKEPAPTTPKGTA---PTTLKEPA-- 656
Query: 333 QAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPE 392
P KPA E+ T+ K T ST + + AP P E A +T P+
Sbjct: 657 ------PTTPKKPAPKELAPTTT-KGPT-STTSDKPAPTTPKETAP--TTPKEPAPTTPK 706
Query: 393 HPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLA 452
P T P + T +P + S E T E+ PT + P +PG+
Sbjct: 707 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKS-PDESTPELSAEPTPKALENSPKEPGV- 764
Query: 453 ITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQ 512
PTT+ +T E T + R+ E T K+ ++++ +E E +
Sbjct: 765 ----PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM--TKETATTTEKTTESK 818
Query: 513 KASTSTNICELCTCGD-----ETLSCVGLSPK 539
+T+T + T TL L+PK
Sbjct: 819 ITATTTQVTSTTTQDTTPFKITTLKTTTLAPK 850
Score = 63.2 bits (152), Expect = 1e-09
Identities = 116/523 (22%), Positives = 177/523 (33%), Gaps = 81/523 (15%)
Query: 23 KEAQPLVWVKDPLQLTSN---PLGPPEPWSSRSSHLPWESPHAPAP-------PAAPGDF 72
KE P K+P T P P +P + +P PAP P P +
Sbjct: 416 KEPSPTT-TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 474
Query: 73 DYLGPSASSQMSALPQEPT--ENLAPFLKELDSAGELPLGPEPFLAAHQDLNDKRTPEER 130
P ++ + PT E LAP E + P PE + TPEE
Sbjct: 475 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA----PTTPEELAPTTPEEPTPTTPEEP 530
Query: 131 LP------------EVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSK 178
P E P ++ + P + T G + P +
Sbjct: 531 APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 590
Query: 179 VSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQL-SKPQRQKQTLPDDYLSMDTLYPGSL 237
+P ++P K+ + P + P+ T P + T G+
Sbjct: 591 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE--PAPTTPKGTA 648
Query: 238 PPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEP 297
P L+ A P P PK P T + S++ + AP P+E P
Sbjct: 649 PTTLKEPAPTTPKKPA----------PKELAPTTTKGPTSTTSDKPAPTT----PKETAP 694
Query: 298 STQQEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPK 357
+T +E P+ + +TP PP + + P T +P + K
Sbjct: 695 TTPKEPAPTTPKKPAPTTPETP--------PPTTSEV--STPTTTKEPTTIH-------K 737
Query: 358 NETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPE-HPEVTLPPSDKGQAQHSHLTEAT- 415
+ EST P E P + TT P PE+T DK + T T
Sbjct: 738 SPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 797
Query: 416 --VQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAP 473
+ E + TTE TTE K + TT + + + T + TT +T T AP
Sbjct: 798 TAAPKMTKETATTTEKTTESKITATTTQVT--------STTTQDTTPFKITTLKTTTLAP 849
Query: 474 HPDQVQTLHRSL--TEVTGPPTKLESSQDSLVQSE-TAPEEQK 513
+V T +++ TE+ P + +D S+ T P+ QK
Sbjct: 850 ---KVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK 889
Score = 62.8 bits (151), Expect = 1e-09
Identities = 81/345 (23%), Positives = 116/345 (33%), Gaps = 49/345 (14%)
Query: 211 QLSKPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPE 270
Q S ++K T + S++ L P +V A +P E PK P
Sbjct: 161 QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-KPTPKAETTTKGPALTTPKEPTPT 219
Query: 271 TLEDIQSSSLQEEAPAQLLQLP---QEVEPSTQQEAPALPPESSMESLAQTPLNHEVTVQ 327
T ++ S++ +E P + P +E P+T + AP P E + T +
Sbjct: 220 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA-----------PTTTK 268
Query: 328 PPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEA-----EPSST 382
P P T +PA E T ++ AP P E A EP+ T
Sbjct: 269 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 328
Query: 383 -----ALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTE--PTTEVKP 435
A T +P P P+ P + K A + A P + + T E PTT +P
Sbjct: 329 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 388
Query: 436 SPTTEE------------------TSAQPPDPGLAITPEPTTEIGHSTALEKTRAP---- 473
+PTT + T+ + P P P PTT + K AP
Sbjct: 389 APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 448
Query: 474 HPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTST 518
P + T P ETAP K T T
Sbjct: 449 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 493
Score = 55.8 bits (133), Expect = 2e-07
Identities = 76/283 (26%), Positives = 102/283 (36%), Gaps = 51/283 (18%)
Query: 264 PKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQE-APALP----PESSMESLAQT 318
PK P T E ++ +E AP P++ P+T +E AP P P ++ E T
Sbjct: 330 PKEPAPTTKEPAPTTP-KEPAPTA----PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 384
Query: 319 PLNHEVTVQPPGEDQAHYNLPKFT----VKPADVEVTMTSEPK----NETESTQAQQEAP 370
P T P T P + T T EP E T ++ AP
Sbjct: 385 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 444
Query: 371 IQPPEEA-----EPSSTALRTTDPPPEHPEVTLP--PSDKGQAQHSHLTEATVQPLDLEL 423
P E A EP+ T T P P P+ P P + LT T + L
Sbjct: 445 TTPKEPAPTTPKEPAPTT--TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL---- 498
Query: 424 SITTEPTTEVKPSPTTEE----TSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQ 479
PTT KP+PTT E T+ + P P P PTT + K AP
Sbjct: 499 ----APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP------ 548
Query: 480 TLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTSTNICE 522
+ + P T E + + ETAP K + T + E
Sbjct: 549 ----TTPKEPAPTTPKEPAPTT--PKETAPTTPKGTAPTTLKE 585
Score = 47.0 bits (110), Expect = 8e-05
Identities = 53/218 (24%), Positives = 80/218 (36%), Gaps = 21/218 (9%)
Query: 304 PALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETEST 363
P+LPP S +N E TV E + K T + T E ++ E T
Sbjct: 128 PSLPPNSDTSKETSLTVNKETTV----ETKETTTTNKQTSTDGKEKTTSAKETQS-IEKT 182
Query: 364 QAQQEAPIQPPEEAEPSSTALRTTDPP----PEHPEVTLPPSDKGQAQHSHLTEATVQPL 419
A+ AP A+P+ A TT P P+ P T P +T
Sbjct: 183 SAKDLAPTS-KVLAKPTPKAETTTKGPALTTPKEPTPTTPKE----------PASTTPKE 231
Query: 420 DLELSITTEPTTEVKPSPTTEETS-AQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQV 478
+I + PTT +P+PTT +++ P +P T EP A T+ P P
Sbjct: 232 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 291
Query: 479 QTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKAST 516
++ + E K + + T P+E +T
Sbjct: 292 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 329
Score = 37.0 bits (84), Expect = 0.087
Identities = 39/209 (18%), Positives = 77/209 (36%), Gaps = 5/209 (2%)
Query: 308 PESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQ 367
P++S + + ++T P + +LP + + +T+ E ET+ T
Sbjct: 102 PDTSTTQHNKVSTSPKITTAKPINPRP--SLPPNSDTSKETSLTVNKETTVETKETTTTN 159
Query: 368 EAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITT 427
+ Q + + +T+ + T + L P+ K A+ + E T + L
Sbjct: 160 K---QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP 216
Query: 428 EPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTE 487
PTT +P+ TT + TP+ +A + P P + + +
Sbjct: 217 TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 276
Query: 488 VTGPPTKLESSQDSLVQSETAPEEQKAST 516
P T E + + + T P+E +T
Sbjct: 277 EPAPTTTKEPAPTTTKSAPTTPKEPAPTT 305
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 63.5 bits (153), Expect = 9e-10
Identities = 117/512 (22%), Positives = 175/512 (34%), Gaps = 72/512 (14%)
Query: 34 PLQLTSNPLGPPEPWSSRSSHLPWESPHAPAPPAAPGDFDYLGPSASSQMSALPQEPTEN 93
P S P P EP + + +P PAP P+ ++ P P E
Sbjct: 446 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK------PAPTTPKEPAPTTPKEP 499
Query: 94 LAPFLKELDSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLK 153
K+ A P P P TP+E P L + L K
Sbjct: 500 APTTTKK--PAPTTPKEPAP-----------TTPKETAPTTPKKLTPTTPEKLAPTTPEK 546
Query: 154 WVQTTDLDRAAGHQADEILVPLDSKVSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLS 213
TT + A E P + PT + N K+ A P + +
Sbjct: 547 PAPTTPEELAP--TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 604
Query: 214 KPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLE 273
P K+T P T G+ P L+ A P P PK P T +
Sbjct: 605 -PTTPKETAP-------TTPKGTAPTTLKEPAPTTPKKPA----------PKELAPTTTK 646
Query: 274 DIQSSSLQEEAPAQLLQLPQEVEPSTQQE-APALPPESSMESLAQTPLNHEVTVQPPGED 332
+ S++ + AP P+ P+T +E AP P E + + T T++ P
Sbjct: 647 EPTSTTCDKPAPTT----PKGTAPTTPKEPAPTTPKEPAPTTPKGTA---PTTLKEPA-- 697
Query: 333 QAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPE 392
P KPA E+ T+ K T ST + + AP P E A +T P+
Sbjct: 698 ------PTTPKKPAPKELAPTTT-KGPT-STTSDKPAPTTPKETAP--TTPKEPAPTTPK 747
Query: 393 HPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLA 452
P T P + T +P + S E T E+ PT + P +PG+
Sbjct: 748 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKS-PDESTPELSAEPTPKALENSPKEPGV- 805
Query: 453 ITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQ 512
PTT+ +T E T + R+ E T K+ ++++ +E E +
Sbjct: 806 ----PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM--TKETATTTEKTTESK 859
Query: 513 KASTSTNICELCTCGD-----ETLSCVGLSPK 539
+T+T + T TL L+PK
Sbjct: 860 ITATTTQVTSTTTQDTTPFKITTLKTTTLAPK 891
Score = 63.2 bits (152), Expect = 1e-09
Identities = 116/523 (22%), Positives = 177/523 (33%), Gaps = 81/523 (15%)
Query: 23 KEAQPLVWVKDPLQLTSN---PLGPPEPWSSRSSHLPWESPHAPAP-------PAAPGDF 72
KE P K+P T P P +P + +P PAP P P +
Sbjct: 457 KEPSPTT-TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 515
Query: 73 DYLGPSASSQMSALPQEPT--ENLAPFLKELDSAGELPLGPEPFLAAHQDLNDKRTPEER 130
P ++ + PT E LAP E + P PE + TPEE
Sbjct: 516 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA----PTTPEELAPTTPEEPTPTTPEEP 571
Query: 131 LP------------EVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSK 178
P E P ++ + P + T G + P +
Sbjct: 572 APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 631
Query: 179 VSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQL-SKPQRQKQTLPDDYLSMDTLYPGSL 237
+P ++P K+ + P + P+ T P + T G+
Sbjct: 632 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE--PAPTTPKGTA 689
Query: 238 PPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEP 297
P L+ A P P PK P T + S++ + AP P+E P
Sbjct: 690 PTTLKEPAPTTPKKPA----------PKELAPTTTKGPTSTTSDKPAPTT----PKETAP 735
Query: 298 STQQEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPK 357
+T +E P+ + +TP PP + + P T +P + K
Sbjct: 736 TTPKEPAPTTPKKPAPTTPETP--------PPTTSEV--STPTTTKEPTTIH-------K 778
Query: 358 NETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPE-HPEVTLPPSDKGQAQHSHLTEAT- 415
+ EST P E P + TT P PE+T DK + T T
Sbjct: 779 SPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 838
Query: 416 --VQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAP 473
+ E + TTE TTE K + TT + + + T + TT +T T AP
Sbjct: 839 TAAPKMTKETATTTEKTTESKITATTTQVT--------STTTQDTTPFKITTLKTTTLAP 890
Query: 474 HPDQVQTLHRSL--TEVTGPPTKLESSQDSLVQSE-TAPEEQK 513
+V T +++ TE+ P + +D S+ T P+ QK
Sbjct: 891 ---KVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK 930
Score = 62.8 bits (151), Expect = 1e-09
Identities = 81/345 (23%), Positives = 116/345 (33%), Gaps = 49/345 (14%)
Query: 211 QLSKPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPE 270
Q S ++K T + S++ L P +V A +P E PK P
Sbjct: 202 QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-KPTPKAETTTKGPALTTPKEPTPT 260
Query: 271 TLEDIQSSSLQEEAPAQLLQLP---QEVEPSTQQEAPALPPESSMESLAQTPLNHEVTVQ 327
T ++ S++ +E P + P +E P+T + AP P E + T +
Sbjct: 261 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA-----------PTTTK 309
Query: 328 PPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEA-----EPSST 382
P P T +PA E T ++ AP P E A EP+ T
Sbjct: 310 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 369
Query: 383 -----ALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTE--PTTEVKP 435
A T +P P P+ P + K A + A P + + T E PTT +P
Sbjct: 370 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 429
Query: 436 SPTTEE------------------TSAQPPDPGLAITPEPTTEIGHSTALEKTRAP---- 473
+PTT + T+ + P P P PTT + K AP
Sbjct: 430 APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 489
Query: 474 HPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTST 518
P + T P ETAP K T T
Sbjct: 490 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 534
Score = 55.8 bits (133), Expect = 2e-07
Identities = 76/283 (26%), Positives = 102/283 (36%), Gaps = 51/283 (18%)
Query: 264 PKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQE-APALP----PESSMESLAQT 318
PK P T E ++ +E AP P++ P+T +E AP P P ++ E T
Sbjct: 371 PKEPAPTTKEPAPTTP-KEPAPTA----PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 425
Query: 319 PLNHEVTVQPPGEDQAHYNLPKFT----VKPADVEVTMTSEPK----NETESTQAQQEAP 370
P T P T P + T T EP E T ++ AP
Sbjct: 426 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 485
Query: 371 IQPPEEA-----EPSSTALRTTDPPPEHPEVTLP--PSDKGQAQHSHLTEATVQPLDLEL 423
P E A EP+ T T P P P+ P P + LT T + L
Sbjct: 486 TTPKEPAPTTPKEPAPTT--TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL---- 539
Query: 424 SITTEPTTEVKPSPTTEE----TSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQ 479
PTT KP+PTT E T+ + P P P PTT + K AP
Sbjct: 540 ----APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP------ 589
Query: 480 TLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTSTNICE 522
+ + P T E + + ETAP K + T + E
Sbjct: 590 ----TTPKEPAPTTPKEPAPTT--PKETAPTTPKGTAPTTLKE 626
Score = 47.0 bits (110), Expect = 8e-05
Identities = 53/218 (24%), Positives = 80/218 (36%), Gaps = 21/218 (9%)
Query: 304 PALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETEST 363
P+LPP S +N E TV E + K T + T E ++ E T
Sbjct: 169 PSLPPNSDTSKETSLTVNKETTV----ETKETTTTNKQTSTDGKEKTTSAKETQS-IEKT 223
Query: 364 QAQQEAPIQPPEEAEPSSTALRTTDPP----PEHPEVTLPPSDKGQAQHSHLTEATVQPL 419
A+ AP A+P+ A TT P P+ P T P +T
Sbjct: 224 SAKDLAPTS-KVLAKPTPKAETTTKGPALTTPKEPTPTTPKE----------PASTTPKE 272
Query: 420 DLELSITTEPTTEVKPSPTTEETS-AQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQV 478
+I + PTT +P+PTT +++ P +P T EP A T+ P P
Sbjct: 273 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 332
Query: 479 QTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKAST 516
++ + E K + + T P+E +T
Sbjct: 333 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 370
Score = 37.0 bits (84), Expect = 0.087
Identities = 39/209 (18%), Positives = 77/209 (36%), Gaps = 5/209 (2%)
Query: 308 PESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQ 367
P++S + + ++T P + +LP + + +T+ E ET+ T
Sbjct: 143 PDTSTTQHNKVSTSPKITTAKPINPRP--SLPPNSDTSKETSLTVNKETTVETKETTTTN 200
Query: 368 EAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITT 427
+ Q + + +T+ + T + L P+ K A+ + E T + L
Sbjct: 201 K---QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP 257
Query: 428 EPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTE 487
PTT +P+ TT + TP+ +A + P P + + +
Sbjct: 258 TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 317
Query: 488 VTGPPTKLESSQDSLVQSETAPEEQKAST 516
P T E + + + T P+E +T
Sbjct: 318 EPAPTTTKEPAPTTTKSAPTTPKEPAPTT 346
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 63.5 bits (153), Expect = 9e-10
Identities = 117/512 (22%), Positives = 175/512 (34%), Gaps = 72/512 (14%)
Query: 34 PLQLTSNPLGPPEPWSSRSSHLPWESPHAPAPPAAPGDFDYLGPSASSQMSALPQEPTEN 93
P S P P EP + + +P PAP P+ ++ P P E
Sbjct: 498 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK------PAPTTPKEPAPTTPKEP 551
Query: 94 LAPFLKELDSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLK 153
K+ A P P P TP+E P L + L K
Sbjct: 552 APTTTKK--PAPTTPKEPAP-----------TTPKETAPTTPKKLTPTTPEKLAPTTPEK 598
Query: 154 WVQTTDLDRAAGHQADEILVPLDSKVSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLS 213
TT + A E P + PT + N K+ A P + +
Sbjct: 599 PAPTTPEELAP--TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 656
Query: 214 KPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLE 273
P K+T P T G+ P L+ A P P PK P T +
Sbjct: 657 -PTTPKETAP-------TTPKGTAPTTLKEPAPTTPKKPA----------PKELAPTTTK 698
Query: 274 DIQSSSLQEEAPAQLLQLPQEVEPSTQQE-APALPPESSMESLAQTPLNHEVTVQPPGED 332
+ S++ + AP P+ P+T +E AP P E + + T T++ P
Sbjct: 699 EPTSTTCDKPAPTT----PKGTAPTTPKEPAPTTPKEPAPTTPKGTA---PTTLKEPA-- 749
Query: 333 QAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPE 392
P KPA E+ T+ K T ST + + AP P E A +T P+
Sbjct: 750 ------PTTPKKPAPKELAPTTT-KGPT-STTSDKPAPTTPKETAP--TTPKEPAPTTPK 799
Query: 393 HPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLA 452
P T P + T +P + S E T E+ PT + P +PG+
Sbjct: 800 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKS-PDESTPELSAEPTPKALENSPKEPGV- 857
Query: 453 ITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQ 512
PTT+ +T E T + R+ E T K+ ++++ +E E +
Sbjct: 858 ----PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM--TKETATTTEKTTESK 911
Query: 513 KASTSTNICELCTCGD-----ETLSCVGLSPK 539
+T+T + T TL L+PK
Sbjct: 912 ITATTTQVTSTTTQDTTPFKITTLKTTTLAPK 943
Score = 63.2 bits (152), Expect = 1e-09
Identities = 116/523 (22%), Positives = 177/523 (33%), Gaps = 81/523 (15%)
Query: 23 KEAQPLVWVKDPLQLTSN---PLGPPEPWSSRSSHLPWESPHAPAP-------PAAPGDF 72
KE P K+P T P P +P + +P PAP P P +
Sbjct: 509 KEPSPTT-TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 567
Query: 73 DYLGPSASSQMSALPQEPT--ENLAPFLKELDSAGELPLGPEPFLAAHQDLNDKRTPEER 130
P ++ + PT E LAP E + P PE + TPEE
Sbjct: 568 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA----PTTPEELAPTTPEEPTPTTPEEP 623
Query: 131 LP------------EVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSK 178
P E P ++ + P + T G + P +
Sbjct: 624 APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 683
Query: 179 VSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQL-SKPQRQKQTLPDDYLSMDTLYPGSL 237
+P ++P K+ + P + P+ T P + T G+
Sbjct: 684 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE--PAPTTPKGTA 741
Query: 238 PPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEP 297
P L+ A P P PK P T + S++ + AP P+E P
Sbjct: 742 PTTLKEPAPTTPKKPA----------PKELAPTTTKGPTSTTSDKPAPTT----PKETAP 787
Query: 298 STQQEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPK 357
+T +E P+ + +TP PP + + P T +P + K
Sbjct: 788 TTPKEPAPTTPKKPAPTTPETP--------PPTTSEV--STPTTTKEPTTIH-------K 830
Query: 358 NETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPE-HPEVTLPPSDKGQAQHSHLTEAT- 415
+ EST P E P + TT P PE+T DK + T T
Sbjct: 831 SPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 890
Query: 416 --VQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAP 473
+ E + TTE TTE K + TT + + + T + TT +T T AP
Sbjct: 891 TAAPKMTKETATTTEKTTESKITATTTQVT--------STTTQDTTPFKITTLKTTTLAP 942
Query: 474 HPDQVQTLHRSL--TEVTGPPTKLESSQDSLVQSE-TAPEEQK 513
+V T +++ TE+ P + +D S+ T P+ QK
Sbjct: 943 ---KVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK 982
Score = 62.8 bits (151), Expect = 1e-09
Identities = 81/345 (23%), Positives = 116/345 (33%), Gaps = 49/345 (14%)
Query: 211 QLSKPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPE 270
Q S ++K T + S++ L P +V A +P E PK P
Sbjct: 254 QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-KPTPKAETTTKGPALTTPKEPTPT 312
Query: 271 TLEDIQSSSLQEEAPAQLLQLP---QEVEPSTQQEAPALPPESSMESLAQTPLNHEVTVQ 327
T ++ S++ +E P + P +E P+T + AP P E + T +
Sbjct: 313 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA-----------PTTTK 361
Query: 328 PPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEA-----EPSST 382
P P T +PA E T ++ AP P E A EP+ T
Sbjct: 362 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 421
Query: 383 -----ALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTE--PTTEVKP 435
A T +P P P+ P + K A + A P + + T E PTT +P
Sbjct: 422 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 481
Query: 436 SPTTEE------------------TSAQPPDPGLAITPEPTTEIGHSTALEKTRAP---- 473
+PTT + T+ + P P P PTT + K AP
Sbjct: 482 APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 541
Query: 474 HPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTST 518
P + T P ETAP K T T
Sbjct: 542 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 586
Score = 55.8 bits (133), Expect = 2e-07
Identities = 76/283 (26%), Positives = 102/283 (36%), Gaps = 51/283 (18%)
Query: 264 PKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQE-APALP----PESSMESLAQT 318
PK P T E ++ +E AP P++ P+T +E AP P P ++ E T
Sbjct: 423 PKEPAPTTKEPAPTTP-KEPAPTA----PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 477
Query: 319 PLNHEVTVQPPGEDQAHYNLPKFT----VKPADVEVTMTSEPK----NETESTQAQQEAP 370
P T P T P + T T EP E T ++ AP
Sbjct: 478 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 537
Query: 371 IQPPEEA-----EPSSTALRTTDPPPEHPEVTLP--PSDKGQAQHSHLTEATVQPLDLEL 423
P E A EP+ T T P P P+ P P + LT T + L
Sbjct: 538 TTPKEPAPTTPKEPAPTT--TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL---- 591
Query: 424 SITTEPTTEVKPSPTTEE----TSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQ 479
PTT KP+PTT E T+ + P P P PTT + K AP
Sbjct: 592 ----APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP------ 641
Query: 480 TLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTSTNICE 522
+ + P T E + + ETAP K + T + E
Sbjct: 642 ----TTPKEPAPTTPKEPAPTT--PKETAPTTPKGTAPTTLKE 678
Score = 47.0 bits (110), Expect = 8e-05
Identities = 53/218 (24%), Positives = 80/218 (36%), Gaps = 21/218 (9%)
Query: 304 PALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETEST 363
P+LPP S +N E TV E + K T + T E ++ E T
Sbjct: 221 PSLPPNSDTSKETSLTVNKETTV----ETKETTTTNKQTSTDGKEKTTSAKETQS-IEKT 275
Query: 364 QAQQEAPIQPPEEAEPSSTALRTTDPP----PEHPEVTLPPSDKGQAQHSHLTEATVQPL 419
A+ AP A+P+ A TT P P+ P T P +T
Sbjct: 276 SAKDLAPTS-KVLAKPTPKAETTTKGPALTTPKEPTPTTPKE----------PASTTPKE 324
Query: 420 DLELSITTEPTTEVKPSPTTEETS-AQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQV 478
+I + PTT +P+PTT +++ P +P T EP A T+ P P
Sbjct: 325 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 384
Query: 479 QTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKAST 516
++ + E K + + T P+E +T
Sbjct: 385 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 422
Score = 37.0 bits (84), Expect = 0.087
Identities = 39/209 (18%), Positives = 77/209 (36%), Gaps = 5/209 (2%)
Query: 308 PESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQ 367
P++S + + ++T P + +LP + + +T+ E ET+ T
Sbjct: 195 PDTSTTQHNKVSTSPKITTAKPINPRP--SLPPNSDTSKETSLTVNKETTVETKETTTTN 252
Query: 368 EAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITT 427
+ Q + + +T+ + T + L P+ K A+ + E T + L
Sbjct: 253 K---QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP 309
Query: 428 EPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTE 487
PTT +P+ TT + TP+ +A + P P + + +
Sbjct: 310 TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 369
Query: 488 VTGPPTKLESSQDSLVQSETAPEEQKAST 516
P T E + + + T P+E +T
Sbjct: 370 EPAPTTTKEPAPTTTKSAPTTPKEPAPTT 398
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 63.5 bits (153), Expect = 9e-10
Identities = 117/512 (22%), Positives = 175/512 (34%), Gaps = 72/512 (14%)
Query: 34 PLQLTSNPLGPPEPWSSRSSHLPWESPHAPAPPAAPGDFDYLGPSASSQMSALPQEPTEN 93
P S P P EP + + +P PAP P+ ++ P P E
Sbjct: 539 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK------PAPTTPKEPAPTTPKEP 592
Query: 94 LAPFLKELDSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLK 153
K+ A P P P TP+E P L + L K
Sbjct: 593 APTTTKK--PAPTTPKEPAP-----------TTPKETAPTTPKKLTPTTPEKLAPTTPEK 639
Query: 154 WVQTTDLDRAAGHQADEILVPLDSKVSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLS 213
TT + A E P + PT + N K+ A P + +
Sbjct: 640 PAPTTPEELAP--TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 697
Query: 214 KPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLE 273
P K+T P T G+ P L+ A P P PK P T +
Sbjct: 698 -PTTPKETAP-------TTPKGTAPTTLKEPAPTTPKKPA----------PKELAPTTTK 739
Query: 274 DIQSSSLQEEAPAQLLQLPQEVEPSTQQE-APALPPESSMESLAQTPLNHEVTVQPPGED 332
+ S++ + AP P+ P+T +E AP P E + + T T++ P
Sbjct: 740 EPTSTTCDKPAPTT----PKGTAPTTPKEPAPTTPKEPAPTTPKGTA---PTTLKEPA-- 790
Query: 333 QAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPE 392
P KPA E+ T+ K T ST + + AP P E A +T P+
Sbjct: 791 ------PTTPKKPAPKELAPTTT-KGPT-STTSDKPAPTTPKETAP--TTPKEPAPTTPK 840
Query: 393 HPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLA 452
P T P + T +P + S E T E+ PT + P +PG+
Sbjct: 841 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKS-PDESTPELSAEPTPKALENSPKEPGV- 898
Query: 453 ITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQ 512
PTT+ +T E T + R+ E T K+ ++++ +E E +
Sbjct: 899 ----PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM--TKETATTTEKTTESK 952
Query: 513 KASTSTNICELCTCGD-----ETLSCVGLSPK 539
+T+T + T TL L+PK
Sbjct: 953 ITATTTQVTSTTTQDTTPFKITTLKTTTLAPK 984
Score = 63.2 bits (152), Expect = 1e-09
Identities = 116/523 (22%), Positives = 177/523 (33%), Gaps = 81/523 (15%)
Query: 23 KEAQPLVWVKDPLQLTSN---PLGPPEPWSSRSSHLPWESPHAPAP-------PAAPGDF 72
KE P K+P T P P +P + +P PAP P P +
Sbjct: 550 KEPSPTT-TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 608
Query: 73 DYLGPSASSQMSALPQEPT--ENLAPFLKELDSAGELPLGPEPFLAAHQDLNDKRTPEER 130
P ++ + PT E LAP E + P PE + TPEE
Sbjct: 609 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA----PTTPEELAPTTPEEPTPTTPEEP 664
Query: 131 LP------------EVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSK 178
P E P ++ + P + T G + P +
Sbjct: 665 APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 724
Query: 179 VSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQL-SKPQRQKQTLPDDYLSMDTLYPGSL 237
+P ++P K+ + P + P+ T P + T G+
Sbjct: 725 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE--PAPTTPKGTA 782
Query: 238 PPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEP 297
P L+ A P P PK P T + S++ + AP P+E P
Sbjct: 783 PTTLKEPAPTTPKKPA----------PKELAPTTTKGPTSTTSDKPAPTT----PKETAP 828
Query: 298 STQQEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPK 357
+T +E P+ + +TP PP + + P T +P + K
Sbjct: 829 TTPKEPAPTTPKKPAPTTPETP--------PPTTSEV--STPTTTKEPTTIH-------K 871
Query: 358 NETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPE-HPEVTLPPSDKGQAQHSHLTEAT- 415
+ EST P E P + TT P PE+T DK + T T
Sbjct: 872 SPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 931
Query: 416 --VQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAP 473
+ E + TTE TTE K + TT + + + T + TT +T T AP
Sbjct: 932 TAAPKMTKETATTTEKTTESKITATTTQVT--------STTTQDTTPFKITTLKTTTLAP 983
Query: 474 HPDQVQTLHRSL--TEVTGPPTKLESSQDSLVQSE-TAPEEQK 513
+V T +++ TE+ P + +D S+ T P+ QK
Sbjct: 984 ---KVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK 1023
Score = 62.8 bits (151), Expect = 1e-09
Identities = 81/345 (23%), Positives = 116/345 (33%), Gaps = 49/345 (14%)
Query: 211 QLSKPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPE 270
Q S ++K T + S++ L P +V A +P E PK P
Sbjct: 295 QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-KPTPKAETTTKGPALTTPKEPTPT 353
Query: 271 TLEDIQSSSLQEEAPAQLLQLP---QEVEPSTQQEAPALPPESSMESLAQTPLNHEVTVQ 327
T ++ S++ +E P + P +E P+T + AP P E + T +
Sbjct: 354 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA-----------PTTTK 402
Query: 328 PPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEA-----EPSST 382
P P T +PA E T ++ AP P E A EP+ T
Sbjct: 403 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 462
Query: 383 -----ALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTE--PTTEVKP 435
A T +P P P+ P + K A + A P + + T E PTT +P
Sbjct: 463 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 522
Query: 436 SPTTEE------------------TSAQPPDPGLAITPEPTTEIGHSTALEKTRAP---- 473
+PTT + T+ + P P P PTT + K AP
Sbjct: 523 APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 582
Query: 474 HPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTST 518
P + T P ETAP K T T
Sbjct: 583 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 627
Score = 55.8 bits (133), Expect = 2e-07
Identities = 76/283 (26%), Positives = 102/283 (36%), Gaps = 51/283 (18%)
Query: 264 PKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQE-APALP----PESSMESLAQT 318
PK P T E ++ +E AP P++ P+T +E AP P P ++ E T
Sbjct: 464 PKEPAPTTKEPAPTTP-KEPAPTA----PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 518
Query: 319 PLNHEVTVQPPGEDQAHYNLPKFT----VKPADVEVTMTSEPK----NETESTQAQQEAP 370
P T P T P + T T EP E T ++ AP
Sbjct: 519 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 578
Query: 371 IQPPEEA-----EPSSTALRTTDPPPEHPEVTLP--PSDKGQAQHSHLTEATVQPLDLEL 423
P E A EP+ T T P P P+ P P + LT T + L
Sbjct: 579 TTPKEPAPTTPKEPAPTT--TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL---- 632
Query: 424 SITTEPTTEVKPSPTTEE----TSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQ 479
PTT KP+PTT E T+ + P P P PTT + K AP
Sbjct: 633 ----APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP------ 682
Query: 480 TLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTSTNICE 522
+ + P T E + + ETAP K + T + E
Sbjct: 683 ----TTPKEPAPTTPKEPAPTT--PKETAPTTPKGTAPTTLKE 719
Score = 47.0 bits (110), Expect = 8e-05
Identities = 53/218 (24%), Positives = 80/218 (36%), Gaps = 21/218 (9%)
Query: 304 PALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETEST 363
P+LPP S +N E TV E + K T + T E ++ E T
Sbjct: 262 PSLPPNSDTSKETSLTVNKETTV----ETKETTTTNKQTSTDGKEKTTSAKETQS-IEKT 316
Query: 364 QAQQEAPIQPPEEAEPSSTALRTTDPP----PEHPEVTLPPSDKGQAQHSHLTEATVQPL 419
A+ AP A+P+ A TT P P+ P T P +T
Sbjct: 317 SAKDLAPTS-KVLAKPTPKAETTTKGPALTTPKEPTPTTPKE----------PASTTPKE 365
Query: 420 DLELSITTEPTTEVKPSPTTEETS-AQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQV 478
+I + PTT +P+PTT +++ P +P T EP A T+ P P
Sbjct: 366 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 425
Query: 479 QTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKAST 516
++ + E K + + T P+E +T
Sbjct: 426 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 463
Score = 37.0 bits (84), Expect = 0.087
Identities = 39/209 (18%), Positives = 77/209 (36%), Gaps = 5/209 (2%)
Query: 308 PESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQ 367
P++S + + ++T P + +LP + + +T+ E ET+ T
Sbjct: 236 PDTSTTQHNKVSTSPKITTAKPINPRP--SLPPNSDTSKETSLTVNKETTVETKETTTTN 293
Query: 368 EAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITT 427
+ Q + + +T+ + T + L P+ K A+ + E T + L
Sbjct: 294 K---QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP 350
Query: 428 EPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTE 487
PTT +P+ TT + TP+ +A + P P + + +
Sbjct: 351 TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 410
Query: 488 VTGPPTKLESSQDSLVQSETAPEEQKAST 516
P T E + + + T P+E +T
Sbjct: 411 EPAPTTTKEPAPTTTKSAPTTPKEPAPTT 439
>gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo
sapiens]
Length = 516
Score = 63.5 bits (153), Expect = 9e-10
Identities = 40/131 (30%), Positives = 72/131 (54%), Gaps = 3/131 (2%)
Query: 560 LNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIE 619
L+ + N+I+ L+ + + ++S L L N ++ + +D+F+GL L+ L LS NKI Y+
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 620 RQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPA 679
TF L LQ ++L N ++ L F +G++ L L L N L T+ ++ +
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELF---YGLRKLQTLHLRSNSLRTIPVRLFWDCRS 182
Query: 680 LKYLDMGTTHI 690
L++LD+ T +
Sbjct: 183 LEFLDLSTNRL 193
Score = 47.4 bits (111), Expect = 6e-05
Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
Query: 558 TTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRY 617
T L+ N IS + + ++ ++LILS N + LP +F L+ LQ LDLS N++
Sbjct: 88 TWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSS 147
Query: 618 IERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNR 663
+ + F L LQ ++L N + + + F ++FL +L NR
Sbjct: 148 LHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFL-DLSTNR 192
Score = 44.7 bits (104), Expect = 4e-04
Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 3/142 (2%)
Query: 560 LNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIE 619
L+ N +S L ++ + L L N L +P F L++LDLS N++R +
Sbjct: 138 LDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLA 197
Query: 620 RQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPA 679
R F L L+ ++L N +TK++ F + LH L L N ++ + +
Sbjct: 198 RNGFAGLIKLRELHLEHNQLTKINFAHFLR---LSSLHTLFLQWNKISNLTCGMEWTWGT 254
Query: 680 LKYLDMGTTHITLTTLKNILTM 701
L+ LD+ I L TM
Sbjct: 255 LEKLDLTGNEIKAIDLTVFETM 276
Score = 31.6 bits (70), Expect = 3.7
Identities = 34/121 (28%), Positives = 55/121 (45%), Gaps = 12/121 (9%)
Query: 559 TLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYI 618
TL Q N IS L + + EKL L+ N + + FE + L+ L + NK+ +
Sbjct: 233 TLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSL 292
Query: 619 ERQTFESLPFLQYINLGCNL------ITKLS--LGTFQAWHGMQFLHNLILNRNPLTTVE 670
+ + SL L + L NL I L+ LG+FQ ++ H+++ + T E
Sbjct: 293 DSKILNSLRSLTTVGLSGNLWECSARICALASWLGSFQG----RWEHSILCHSPDHTQGE 348
Query: 671 D 671
D
Sbjct: 349 D 349
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 62.4 bits (150), Expect = 2e-09
Identities = 46/162 (28%), Positives = 70/162 (43%), Gaps = 27/162 (16%)
Query: 524 CTCGDETLSCVGLSPKQRLRQVPVPEPDTYNGI--------------------FTTLNFQ 563
CTC + + C G + L ++P P+T I ++
Sbjct: 277 CTCSNNIVDCRG----KGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLS 332
Query: 564 GNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTF 623
N IS L + ++ L+L N +TELPK FEGL LQ L L+ NKI + F
Sbjct: 333 NNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAF 392
Query: 624 ESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNP 665
+ L L ++L N + ++ GTF +Q +H L +NP
Sbjct: 393 QDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMH---LAQNP 431
Score = 54.3 bits (129), Expect = 5e-07
Identities = 63/255 (24%), Positives = 106/255 (41%), Gaps = 28/255 (10%)
Query: 524 CTCGDETLSCVGLSPKQRLRQVPV-PEPDTYNGI----FTTLNFQG-----------NYI 567
C+C T+ C GL+ + R +P E NG T +F G N I
Sbjct: 32 CSCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKI 91
Query: 568 SYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLP 627
S ++ ++ E+L L+ N+L P+ F G L LDLS N+I+ I R+ F
Sbjct: 92 STIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAV 151
Query: 628 FLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGT 687
++ + L N I+ + G F+A ++ L L LN N +T + +P L+ + +
Sbjct: 152 DIKNLQLDYNQISCIEDGAFRA---LRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHS 208
Query: 688 THI----TLTTLKNILTMTVEL---EKLILPSHMACCLCQFKNSIEAVCKTVKLHCNTAC 740
++ L L + L + + + PSH+ E VC + +C
Sbjct: 209 NNLYCDCHLAWLSDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCSGHQSFMAPSC 268
Query: 741 LTNSIHCPEEASVGN 755
+ +HCP + N
Sbjct: 269 --SVLHCPAACTCSN 281
Score = 50.1 bits (118), Expect = 1e-05
Identities = 42/162 (25%), Positives = 69/162 (42%), Gaps = 26/162 (16%)
Query: 522 ELCTCGDETLSCVGLSPKQRLRQVPVPEPD---------------TYNGIFTTL------ 560
E C C T+ C Q+L ++P P GIF L
Sbjct: 508 EKCRCEGTTVDC----SNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKI 563
Query: 561 NFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIER 620
NF N I+ ++ ++ S +++L+ N L + F+GL L+ L L N+I +
Sbjct: 564 NFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGN 623
Query: 621 QTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILN 662
+F L ++ ++L N IT ++ G F H + L NL+ N
Sbjct: 624 DSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTL-NLLAN 664
Score = 43.5 bits (101), Expect = 0.001
Identities = 47/213 (22%), Positives = 77/213 (36%), Gaps = 19/213 (8%)
Query: 499 QDSLVQSETAPE---EQKASTSTNICELCTCGDETLSCVGLSPKQRLRQVP--------- 546
QD +Q T + + S + CTC D + C K + +P
Sbjct: 703 QDVAIQDFTCDDGNDDNSCSPLSRCPTECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLD 762
Query: 547 ------VPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFE 600
VP+ + T ++ N IS L + + LILS N L +P +F+
Sbjct: 763 GNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFD 822
Query: 601 GLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCN-LITKLSLGTFQAWHGMQFLHNL 659
GL L+ L L N I + F L L ++ +G N L ++ W ++
Sbjct: 823 GLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSDWVKSEYKEPG 882
Query: 660 ILNRNPLTTVEDPYLFELPALKYLDMGTTHITL 692
I + D L P+ K+ G + +
Sbjct: 883 IARCAGPGEMADKLLLTTPSKKFTCQGPVDVNI 915
>gi|156139147 leucine rich repeat transmembrane neuronal 4 isoform b
[Homo sapiens]
Length = 518
Score = 62.0 bits (149), Expect = 3e-09
Identities = 45/161 (27%), Positives = 78/161 (48%), Gaps = 4/161 (2%)
Query: 550 PDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLD 609
P+ +G L+ + N I L N + + L L NY++ + +D+F+G+ L+ L
Sbjct: 56 PENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELI 115
Query: 610 LSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTV 669
LS NKI Y+ +TF +P L+ ++L N + L F+ + LH L N L TV
Sbjct: 116 LSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILH---LRSNSLKTV 172
Query: 670 EDPYLFELPALKYLDMGTTHITLTTLKNILTMTVELEKLIL 710
+ L +LD+G + + +N ++L++L L
Sbjct: 173 PIRVFQDCRNLDFLDLGYNRLR-SLSRNAFAGLLKLKELHL 212
Score = 42.0 bits (97), Expect = 0.003
Identities = 23/46 (50%), Positives = 28/46 (60%)
Query: 605 LQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAW 650
L LDLS N I+ IE TF+ LP LQ +NL N +T +S T AW
Sbjct: 255 LHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAW 300
>gi|197927168 leucine rich repeat transmembrane neuronal 4 isoform a
[Homo sapiens]
Length = 590
Score = 62.0 bits (149), Expect = 3e-09
Identities = 45/161 (27%), Positives = 78/161 (48%), Gaps = 4/161 (2%)
Query: 550 PDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLD 609
P+ +G L+ + N I L N + + L L NY++ + +D+F+G+ L+ L
Sbjct: 56 PENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELI 115
Query: 610 LSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTV 669
LS NKI Y+ +TF +P L+ ++L N + L F+ + LH L N L TV
Sbjct: 116 LSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILH---LRSNSLKTV 172
Query: 670 EDPYLFELPALKYLDMGTTHITLTTLKNILTMTVELEKLIL 710
+ L +LD+G + + +N ++L++L L
Sbjct: 173 PIRVFQDCRNLDFLDLGYNRLR-SLSRNAFAGLLKLKELHL 212
Score = 42.0 bits (97), Expect = 0.003
Identities = 23/46 (50%), Positives = 28/46 (60%)
Query: 605 LQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAW 650
L LDLS N I+ IE TF+ LP LQ +NL N +T +S T AW
Sbjct: 255 LHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAW 300
>gi|7662320 leucine-rich repeats and immunoglobulin-like domains 2
[Homo sapiens]
Length = 1065
Score = 62.0 bits (149), Expect = 3e-09
Identities = 46/158 (29%), Positives = 77/158 (48%), Gaps = 2/158 (1%)
Query: 565 NYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFE 624
N I + + W+ +L LS N LT L + +F GL L+ L+L N++ +I F
Sbjct: 297 NAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFR 356
Query: 625 SLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLD 684
L LQ ++L N I+ +A+ G+ L LIL N + ++ L +L++LD
Sbjct: 357 FLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLD 416
Query: 685 MGTTHITLTTLKNILTMTVELEKLILPSHMACCLCQFK 722
+ I ++ +N + T L++LIL + C C K
Sbjct: 417 LNNNAI-MSIQENAFSQT-HLKELILNTSSLLCDCHLK 452
Score = 52.0 bits (123), Expect = 3e-06
Identities = 39/125 (31%), Positives = 66/125 (52%), Gaps = 5/125 (4%)
Query: 560 LNFQGNYISYLDGNVWKAYSWTEKLI-LSENYLTELPKDSFEGLLYLQYLDLSCNKIRYI 618
LN N I+ L+ + S + ++ L+ N ++ +P F+ L +LQ+L+L N+I+ +
Sbjct: 172 LNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPHLQFLELKRNRIKIV 230
Query: 619 ERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELP 678
E TF+ L L+ + + N I+KL G F G+ + L L N LT V +L+ L
Sbjct: 231 EGLTFQGLDSLRSLKMQRNGISKLKDGAF---FGLNNMEELELEHNNLTRVNKGWLYGLR 287
Query: 679 ALKYL 683
L+ L
Sbjct: 288 MLQQL 292
Score = 48.5 bits (114), Expect = 3e-05
Identities = 46/174 (26%), Positives = 78/174 (44%), Gaps = 30/174 (17%)
Query: 542 LRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEG 601
L ++P T N T L+ N I ++ + Y E L LS N ++E+ SF
Sbjct: 109 LTEIPYFGEPTSN--ITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPR 166
Query: 602 LLYLQYLDLSCNKIRYIERQTFES------------------------LPFLQYINLGCN 637
+ L+YL+LS N+I +E F++ LP LQ++ L N
Sbjct: 167 M-QLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRN 225
Query: 638 LITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHIT 691
I + TFQ G+ L +L + RN ++ ++D F L ++ L++ ++T
Sbjct: 226 RIKIVEGLTFQ---GLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLT 276
Score = 38.1 bits (87), Expect = 0.039
Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 9/126 (7%)
Query: 534 VGLSPKQRLRQVPVPEPDTYNGIFT------TLNFQGNYISYLDGNVWKAYSWTE---KL 584
VGLS +RL +G+F TL+ + N IS+ + +A++ KL
Sbjct: 332 VGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKL 391
Query: 585 ILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSL 644
IL N + + K +F GL L++LDL+ N I I+ F + I +L+ L
Sbjct: 392 ILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTHLKELILNTSSLLCDCHL 451
Query: 645 GTFQAW 650
W
Sbjct: 452 KWLLQW 457
>gi|40255157 leucine-rich repeats and immunoglobulin-like domains 3
isoform 2 [Homo sapiens]
Length = 1119
Score = 61.6 bits (148), Expect = 3e-09
Identities = 58/233 (24%), Positives = 99/233 (42%), Gaps = 8/233 (3%)
Query: 560 LNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIE 619
L+ N I+ + + W+ +L L+ N+L+ L SF GL L L + N++ YI
Sbjct: 292 LHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIA 351
Query: 620 RQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPA 679
F L L+ ++L N I+ A+ G+ L LIL N + ++ L A
Sbjct: 352 DCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDA 411
Query: 680 LKYLDMGTTHITLTTLKNILTMTVELEKLILPSHMACCLCQFKNSIEAVCK-TVKLHCNT 738
L++LD+ I ++ N + +L++L L + C CQ K + V + + N
Sbjct: 412 LEHLDLSDNAI-MSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNA 470
Query: 739 ACLTNSIHCPEEASVGNPEGAFMKMLQARKQHMSTQLTIESEAPSDSSGINLS 791
+C + +P+G Q+T++ E S G NLS
Sbjct: 471 SCAHPQLLKGRSIFAVSPDGFVC------DDFPKPQITVQPETQSAIKGSNLS 517
Score = 54.3 bits (129), Expect = 5e-07
Identities = 50/159 (31%), Positives = 74/159 (46%), Gaps = 7/159 (4%)
Query: 555 GIFTTLNFQGNYISYL-DGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCN 613
G +L Q N ++ L DG W S E L L N LTE+ K GLL LQ L LS N
Sbjct: 239 GALKSLKMQRNGVTKLMDGAFW-GLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQN 297
Query: 614 KIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPY 673
I I +E L ++L N +++L +F G+ L+ L + N ++ + D
Sbjct: 298 AINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFL---GLSLLNTLHIGNNRVSYIADCA 354
Query: 674 LFELPALKYLDMGTTHI--TLTTLKNILTMTVELEKLIL 710
L +LK LD+ I T+ + + +L +LIL
Sbjct: 355 FRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLIL 393
Score = 48.1 bits (113), Expect = 4e-05
Identities = 34/107 (31%), Positives = 57/107 (53%), Gaps = 4/107 (3%)
Query: 584 LILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLS 643
L L+ N ++ +P F+ L LQ+L+L+ NKI+ ++ TF+ L L+ + + N +TKL
Sbjct: 197 LKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLM 255
Query: 644 LGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHI 690
G F M+ L L+ N LT + +L+ L L+ L + I
Sbjct: 256 DGAFWGLSNMEILQ---LDHNNLTEITKGWLYGLLMLQELHLSQNAI 299
Score = 44.7 bits (104), Expect = 4e-04
Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 3/105 (2%)
Query: 556 IFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKD---SFEGLLYLQYLDLSC 612
+ TL+ N +SY+ ++ S + L L N ++ +D +F GL L+ L L
Sbjct: 336 LLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQG 395
Query: 613 NKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLH 657
N+IR I ++ F L L++++L N I L F +Q LH
Sbjct: 396 NRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLH 440
Score = 41.6 bits (96), Expect = 0.004
Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 3/79 (3%)
Query: 559 TLNFQGNYISYLDGNVWKAYSWTEKL---ILSENYLTELPKDSFEGLLYLQYLDLSCNKI 615
TL+ + N IS+ ++ A+S +KL IL N + + K +F GL L++LDLS N I
Sbjct: 363 TLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAI 422
Query: 616 RYIERQTFESLPFLQYINL 634
++ F + LQ ++L
Sbjct: 423 MSLQGNAFSQMKKLQQLHL 441
Score = 41.2 bits (95), Expect = 0.005
Identities = 48/165 (29%), Positives = 75/165 (45%), Gaps = 15/165 (9%)
Query: 536 LSPKQRLRQVP--------VPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILS 587
+S Q LR+V +P + T L+ GN I + K + E L LS
Sbjct: 94 MSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLS 153
Query: 588 ENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLP-FLQYINLGCNLITKLSLGT 646
N ++EL + +F L L+YL L+ N++ +E F++L L + L N I+ +
Sbjct: 154 SNNISEL-QTAFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKM 211
Query: 647 FQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHIT 691
F+ + L +L LNRN + V+ L ALK L M +T
Sbjct: 212 FK----LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVT 252
>gi|209862903 leucine-rich repeats and immunoglobulin-like domains 3
isoform 1 [Homo sapiens]
Length = 1059
Score = 61.6 bits (148), Expect = 3e-09
Identities = 58/233 (24%), Positives = 99/233 (42%), Gaps = 8/233 (3%)
Query: 560 LNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIE 619
L+ N I+ + + W+ +L L+ N+L+ L SF GL L L + N++ YI
Sbjct: 232 LHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIA 291
Query: 620 RQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPA 679
F L L+ ++L N I+ A+ G+ L LIL N + ++ L A
Sbjct: 292 DCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDA 351
Query: 680 LKYLDMGTTHITLTTLKNILTMTVELEKLILPSHMACCLCQFKNSIEAVCK-TVKLHCNT 738
L++LD+ I ++ N + +L++L L + C CQ K + V + + N
Sbjct: 352 LEHLDLSDNAI-MSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNA 410
Query: 739 ACLTNSIHCPEEASVGNPEGAFMKMLQARKQHMSTQLTIESEAPSDSSGINLS 791
+C + +P+G Q+T++ E S G NLS
Sbjct: 411 SCAHPQLLKGRSIFAVSPDGFVC------DDFPKPQITVQPETQSAIKGSNLS 457
Score = 54.3 bits (129), Expect = 5e-07
Identities = 50/159 (31%), Positives = 74/159 (46%), Gaps = 7/159 (4%)
Query: 555 GIFTTLNFQGNYISYL-DGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCN 613
G +L Q N ++ L DG W S E L L N LTE+ K GLL LQ L LS N
Sbjct: 179 GALKSLKMQRNGVTKLMDGAFW-GLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQN 237
Query: 614 KIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPY 673
I I +E L ++L N +++L +F G+ L+ L + N ++ + D
Sbjct: 238 AINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFL---GLSLLNTLHIGNNRVSYIADCA 294
Query: 674 LFELPALKYLDMGTTHI--TLTTLKNILTMTVELEKLIL 710
L +LK LD+ I T+ + + +L +LIL
Sbjct: 295 FRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLIL 333
Score = 48.1 bits (113), Expect = 4e-05
Identities = 34/107 (31%), Positives = 57/107 (53%), Gaps = 4/107 (3%)
Query: 584 LILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLS 643
L L+ N ++ +P F+ L LQ+L+L+ NKI+ ++ TF+ L L+ + + N +TKL
Sbjct: 137 LKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLM 195
Query: 644 LGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHI 690
G F M+ L L+ N LT + +L+ L L+ L + I
Sbjct: 196 DGAFWGLSNMEILQ---LDHNNLTEITKGWLYGLLMLQELHLSQNAI 239
Score = 44.7 bits (104), Expect = 4e-04
Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 3/105 (2%)
Query: 556 IFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKD---SFEGLLYLQYLDLSC 612
+ TL+ N +SY+ ++ S + L L N ++ +D +F GL L+ L L
Sbjct: 276 LLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQG 335
Query: 613 NKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLH 657
N+IR I ++ F L L++++L N I L F +Q LH
Sbjct: 336 NRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLH 380
Score = 41.6 bits (96), Expect = 0.004
Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 3/79 (3%)
Query: 559 TLNFQGNYISYLDGNVWKAYSWTEKL---ILSENYLTELPKDSFEGLLYLQYLDLSCNKI 615
TL+ + N IS+ ++ A+S +KL IL N + + K +F GL L++LDLS N I
Sbjct: 303 TLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAI 362
Query: 616 RYIERQTFESLPFLQYINL 634
++ F + LQ ++L
Sbjct: 363 MSLQGNAFSQMKKLQQLHL 381
Score = 41.2 bits (95), Expect = 0.005
Identities = 48/165 (29%), Positives = 75/165 (45%), Gaps = 15/165 (9%)
Query: 536 LSPKQRLRQVP--------VPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILS 587
+S Q LR+V +P + T L+ GN I + K + E L LS
Sbjct: 34 MSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLS 93
Query: 588 ENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLP-FLQYINLGCNLITKLSLGT 646
N ++EL + +F L L+YL L+ N++ +E F++L L + L N I+ +
Sbjct: 94 SNNISEL-QTAFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKM 151
Query: 647 FQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHIT 691
F+ + L +L LNRN + V+ L ALK L M +T
Sbjct: 152 FK----LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVT 192
>gi|194272183 G protein-coupled receptor 124 [Homo sapiens]
Length = 1338
Score = 60.8 bits (146), Expect = 6e-09
Identities = 60/218 (27%), Positives = 82/218 (37%), Gaps = 36/218 (16%)
Query: 508 APEEQKASTSTNICELCTC-GDETLSCVGLSPKQRLRQVPV--------PEPDTYNGIFT 558
APE + A C C G+ G P R+V PEP
Sbjct: 28 APEARGAPGCPLSIRSCKCSGERPKGLSGGVPGPARRRVVCSGGDLPEPPEPGLLPNGTV 87
Query: 559 TLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYI 618
TL N I+ L + S EKL L N ++ + +F GL L+ LDLS N+I +
Sbjct: 88 TLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCL 147
Query: 619 ERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELP 678
+TF+ LP L +N+ N+ + L G F ELP
Sbjct: 148 TSETFQGLPRLLRLNISGNIFSSLQPGVFD---------------------------ELP 180
Query: 679 ALKYLDMGTTHITLTTLKNILTMTVELEKLILPSHMAC 716
ALK +D+GT +T L + L L H C
Sbjct: 181 ALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLC 218
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 60.5 bits (145), Expect = 7e-09
Identities = 99/438 (22%), Positives = 176/438 (40%), Gaps = 73/438 (16%)
Query: 44 PPEPWSSRSSHLPWESPHAPAPPAAPGDF-DYLGPSASSQMSALPQEPT-ENLAPFLKEL 101
PP+P S +E P A P + + P+A Q++ P++P E AP + +
Sbjct: 10655 PPKPESPPPE--VFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAV--V 10710
Query: 102 DSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLD 161
ELP P ++ + PE+++P VVP + ++P+
Sbjct: 10711 AKKPELPPVKVP------EVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKE--------- 10755
Query: 162 RAAGHQADEILVPLDSKVSRPTKFVVSPKNL-----KKDLAERWSLPEIVGIPHQLSKPQ 216
+VP + KV+ P K V P + K L E+ ++P +P + P
Sbjct: 10756 ----------VVP-EKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVP----VPERAESPP 10800
Query: 217 RQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQ 276
+ P++ + + P P +EP PP V + P+ + P ++ +
Sbjct: 10801 PEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVP-VIKKPE 10859
Query: 277 SSSLQEEAPAQLLQLPQEVEPSTQQEAPALPPESSMESL--------------AQTPLNH 322
+ +E P ++++ P+ ++P PA P E E + Q P
Sbjct: 10860 APPPKEPEPEKVIEKPK-LKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKV 10918
Query: 323 EVTVQ--PPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEAEPS 380
E+T P GE + LP+ +P + EV + S + E ++E ++P + +
Sbjct: 10919 ELTPLKVPGGEKKVRKLLPERKPEPKE-EVVLKSVLRKRPE----EEEPKVEPKKLEKVK 10973
Query: 381 STALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTE 440
A+ PP EV +P K + + + E T P +++ +I P E KP P E
Sbjct: 10974 KPAVPEPPPPKPVEEVEVPTVTKRERK---IPEPTKVP-EIKPAIPL-PAPEPKPKPEAE 11028
Query: 441 ETSAQPPDPGLAITPEPT 458
+ +PP + PEPT
Sbjct: 11029 VKTIKPP----PVEPEPT 11042
Score = 55.8 bits (133), Expect = 2e-07
Identities = 78/368 (21%), Positives = 140/368 (38%), Gaps = 48/368 (13%)
Query: 173 VPLDSKVSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTL 232
+ ++ KV P + V P + + L + +PE KP+ +P+
Sbjct: 10476 IVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEA------- 10528
Query: 233 YPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLP 292
P + PE +V P P +V ++ PK+ PE E P ++ + P
Sbjct: 10529 -PKEVVPEKKVPVPPPKKP--EVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAP 10585
Query: 293 QEVEPSTQQEAPALPPESSMESLAQTPL-------NHEVTVQPPGEDQAHYN----LPKF 341
+EV P +++ PA PP+ + + P +V V PP + + +PK
Sbjct: 10586 KEVVP--EKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKV 10643
Query: 342 TVKPADVEVTMTSEPKN------ETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPE 395
V V + +P++ E A +E P + EE EP++ T P PE
Sbjct: 10644 AVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPE 10703
Query: 396 VTLPP--SDKGQAQHSHLTEATVQPL-DLELSITTEPTTEVKPSPTTEETSAQPPDPGLA 452
P + K + + E + + + ++ + E P+ E P+ +A
Sbjct: 10704 KKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVA 10763
Query: 453 ITPEPTT------EIGHSTALE-KTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQS 505
+ +P E+ LE K P P++ ++ PP E ++ +
Sbjct: 10764 VPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAES---------PPPEVYEEPEEIAPEE 10814
Query: 506 ETAPEEQK 513
E APEE+K
Sbjct: 10815 EIAPEEEK 10822
Score = 51.2 bits (121), Expect = 4e-06
Identities = 65/280 (23%), Positives = 101/280 (36%), Gaps = 49/280 (17%)
Query: 271 TLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQEAPALPPESSMESLAQTPLNHEVTVQPPG 330
T+ ++Q + EE + + + VEP + P LP + + E +A P+ +V +PP
Sbjct: 9260 TVPEVQKEIVTEEKIH--VAISKRVEPPPK--VPELPEKPAPEEVAPVPIPKKV--EPPA 9313
Query: 331 EDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQP-PEEAEPSSTALRTTDP 389
+P+ KP E PK E + E P +P PEE P A + P
Sbjct: 9314 P-----KVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAP 9368
Query: 390 PPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEV----KPSPTTEETSAQ 445
P + PEV KG +T T + ++ P +V KP P EE
Sbjct: 9369 PAKVPEV-----QKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPP 9423
Query: 446 PPD------------------PGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTE 487
PP P P P E+ T +E+ R +++ E
Sbjct: 9424 PPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVE 9483
Query: 488 VTGPPTKLESSQD----------SLVQSETAPEEQKASTS 517
VT E S+ + E EE++A +
Sbjct: 9484 VTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVT 9523
Score = 49.3 bits (116), Expect = 2e-05
Identities = 91/407 (22%), Positives = 146/407 (35%), Gaps = 75/407 (18%)
Query: 87 PQEPTENLAPFLKELDSAGELPLGP--EPFLAAHQ--DLNDKRTPEERLPEVVPLLNRDQ 142
P+ P + KE+ ++P+ P +P + + ++ PE+++PE +P
Sbjct: 10518 PEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESP 10577
Query: 143 NQALVQLPRLKWVQTTDLDRAAGHQADEIL---VPLDSKVSRPTKFVVSPKNLKKDLAER 199
+ + P K V AA + E+ VP K P K V P K ++
Sbjct: 10578 PPEVPEAP--KEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPT 10635
Query: 200 WSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPEL-----RVNADEPPGP--- 251
+PE+ P ++ + +P P S PPE+ V +EPP
Sbjct: 10636 -KVPEV---PKVAVPEKKVPEAIPPK--------PESPPPEVFEEPEEVALEEPPAEVVE 10683
Query: 252 -PEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQEAPALPPES 310
PE Q + PK PE + E P ++ ++P+EV P +++ P + P+
Sbjct: 10684 EPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVP--EKKVPLVVPKK 10741
Query: 311 SMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAP 370
A+ P +PK V V V PK E P
Sbjct: 10742 PEAPPAKVP-----------------EVPKEVVPEKKVAV-----PKKPEVPPAKVPEVP 10779
Query: 371 IQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPT 430
+P E +P+ + PP PEV P + + P E I E
Sbjct: 10780 KKPVLEEKPAVPVPERAESPP--PEVYEEPEE-------------IAP---EEEIAPE-- 10819
Query: 431 TEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQ 477
E KP P EE + P P + P+ ++K AP P +
Sbjct: 10820 -EEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKE 10865
Score = 48.1 bits (113), Expect = 4e-05
Identities = 61/275 (22%), Positives = 108/275 (39%), Gaps = 35/275 (12%)
Query: 246 DEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEV---EPSTQQE 302
++P PP+ +S+ + PK + + ++E PA++ ++P+++ E E
Sbjct: 10434 EKPKAPPKGPEISEKIIPPKKPPTKVVP-------RKEPPAKVPEVPKKIVVEEKVRVPE 10486
Query: 303 APALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADV----EVTMTSEPKN 358
P +PP E L + E V P + PK P +V +V + K
Sbjct: 10487 EPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKP 10546
Query: 359 ETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPE----------VTLPPSDKGQAQH 408
E T+ + PE+ P + + PPPE PE V P K +
Sbjct: 10547 EVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTP 10606
Query: 409 SHLTEATVQPL-DLELSITTEPTTEVKPSPTTEETSAQPPDPGL--AITPEPTT------ 459
+ EA + + + ++ + EV P+ E P+ + AI P+P +
Sbjct: 10607 VKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVF 10666
Query: 460 EIGHSTALEKTRAPHPDQVQTLHRSLTEVTGPPTK 494
E ALE+ A ++ + + +VT PP K
Sbjct: 10667 EEPEEVALEEPPAEVVEEPEP--AAPPQVTVPPKK 10699
Score = 43.9 bits (102), Expect = 7e-04
Identities = 77/360 (21%), Positives = 137/360 (38%), Gaps = 60/360 (16%)
Query: 58 ESPHAPAPPAA-PGDFDYLGPSASSQMSALPQEPTENLAPFLKELDSAGELPLGPEPFLA 116
E P P P P + +++ +P++P E + P L +P +P A
Sbjct: 9952 EVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKV-PVL--------IPKKEKPPPA 10002
Query: 117 AHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLD 176
++ K PEE++P VP + ++P+ + ++ VP
Sbjct: 10003 KVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEK------------KVPVPAP 10050
Query: 177 SKVSRP-TKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPG 235
KV P K PK L + + +P+ V P K ++++ +P P
Sbjct: 10051 KKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPP--KVPKKREPVP---------VPV 10099
Query: 236 SLPPELRVNADEPPGPPEQVGLSQFHLEPKSQN--PETLEDIQSSSL----QEEAPAQLL 289
+LP E V +E P E+V + + P+ + PE E + +EE P +
Sbjct: 10100 ALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEE 10159
Query: 290 QLPQEVEPSTQQEA-----PALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVK 344
+P+E E ++E P +P + + + + +V + P E+ +P+ K
Sbjct: 10160 YVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVI-PKKEEAPPAKVPEVPKK 10218
Query: 345 --------PADVEVTMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEV 396
P + EV + E +++E P +PP E A PP PEV
Sbjct: 10219 VEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVA------PPRVPEV 10272
Score = 41.2 bits (95), Expect = 0.005
Identities = 63/292 (21%), Positives = 103/292 (35%), Gaps = 37/292 (12%)
Query: 246 DEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQ----- 300
+EP PP +V L PK PE + + E P ++ + P+EV P +
Sbjct: 10486 EEPRVPPTKVPEV---LPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPP 10542
Query: 301 QEAPALPPESSME-SLAQTPLNHEVTVQPPGEDQAHYNLPKF-----------TVKPADV 348
+ P +PP E A P PP + +P+ P
Sbjct: 10543 PKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKP 10602
Query: 349 EVTMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQA-- 406
EVT P+ E +++ P+ PP++ E T + PE P+V +P +A
Sbjct: 10603 EVTPVKVPEAPKE-VVPEKKVPVPPPKKPEVPPTKV------PEVPKVAVPEKKVPEAIP 10655
Query: 407 --QHSHLTEATVQPLDLELSITTEPTTEV--KPSPTTEETSAQPPDPGLAITPEPTTEIG 462
S E +P ++ L EP EV +P P PP + P +
Sbjct: 10656 PKPESPPPEVFEEPEEVALE---EPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAV-VA 10711
Query: 463 HSTALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKA 514
L + P + + + V + ++ V E PE++ A
Sbjct: 10712 KKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVA 10763
Score = 39.3 bits (90), Expect = 0.018
Identities = 54/264 (20%), Positives = 92/264 (34%), Gaps = 27/264 (10%)
Query: 264 PKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQEAPA-------------LPPES 310
PK PE + E PA++ ++P++ P + PA +P +
Sbjct: 10008 PKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKL 10067
Query: 311 SMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAP 370
E TP+ +V PP + +P P + EV E E E ++E
Sbjct: 10068 IPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEE-- 10125
Query: 371 IQPPEE---AEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITT 427
+ P EE E + PPE EV P + + + E V P
Sbjct: 10126 VLPEEEEVLPEEEEVLPEEEEIPPEEEEVP-PEEEYVPEEEEFVPEEEVLPEVKPKVPVP 10184
Query: 428 EPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTE 487
P E+K T ++ + P E+ ++ P ++V + E
Sbjct: 10185 APVPEIKKKVTEKKVVIPKKEEA---PPAKVPEVPKKVEEKRIILPKEEEVLPV-----E 10236
Query: 488 VTGPPTKLESSQDSLVQSETAPEE 511
VT P + S++ + + + EE
Sbjct: 10237 VTEEPEEEPISEEEIPEEPPSIEE 10260
Score = 34.3 bits (77), Expect = 0.57
Identities = 61/307 (19%), Positives = 105/307 (34%), Gaps = 41/307 (13%)
Query: 234 PGSLPPELRVNADEPPGPPEQVGLSQFHLE----PKSQNPETLEDIQSSSLQEEAPAQLL 289
P +P +L+ + P P++V + + K Q E + + A ++
Sbjct: 9825 PVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVP 9884
Query: 290 QLPQEVEPSTQQEAPALPPESSMESLA--QTPLNHEVTVQPPGEDQAHYNLPKFTVKPAD 347
+EV P + P +P E E +A + + H E++ + +F +
Sbjct: 9885 VPRKEVAPPVR--VPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEV 9942
Query: 348 VEVTMTSEPKNETESTQAQQEAPIQP-PEEAEPSSTALRTTDPPPEHPEVTLPPSDK--- 403
V V P E P +P PEE +P + PP + PEV P +K
Sbjct: 9943 VPVIPVKVP-----------EVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPV 9991
Query: 404 -------------GQAQHSHLTEATVQ-PLDLELSITTEPTTEVKPSPTTEETSAQPPDP 449
+ + E V P+ ++ EV P E+ P
Sbjct: 9992 LIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPK 10051
Query: 450 GLAITPEPTTEIGHS-TALEKTRAPHPDQVQTLHRSLTEVTGP---PTKLESSQDSLVQS 505
+ P E+ EK P P +V+ + + P P L ++ L +
Sbjct: 10052 KVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEE 10111
Query: 506 ETAPEEQ 512
E PEE+
Sbjct: 10112 EIVPEEE 10118
Score = 32.0 bits (71), Expect = 2.8
Identities = 65/333 (19%), Positives = 113/333 (33%), Gaps = 66/333 (19%)
Query: 174 PLDSKVSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLY 233
P +KV K +V K + + ++ +P +P + KP +K+ +P + M+
Sbjct: 9575 PPPAKVPEAPKKIVPEKKVPAPVPKKEKVPP-PKVPEEPKKPVPEKK-VPPKVIKMEEPL 9632
Query: 234 PGSLPP---------ELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEA 284
P + ++ V + PP+ ++ EPK PE +EE
Sbjct: 9633 PAKVTERHMQITQEEKVLVAVTKKEAPPK----ARVPEEPKRAVPEEKVLKLKPKREEEP 9688
Query: 285 PAQLLQLPQEV--EPSTQQEAPALPPESSME-------SLAQTPLNHEVTVQPPGEDQAH 335
PA++ + + V E EAP P+ E A T V+VQ E + +
Sbjct: 9689 PAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEY 9748
Query: 336 --YNLPKFTVKPADVEVTMTSE---------PKNETESTQAQQEAPIQP----------- 373
Y+ +F E E ++E T+ ++ P++P
Sbjct: 9749 EEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPK 9808
Query: 374 -----------PEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLE 422
PEE P + PPP+ PE + + + + E
Sbjct: 9809 APPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPE---------EPKKVFEEKIRISITKRE 9859
Query: 423 LSITTEPTTEVKPSPTTEETSAQPPDPGLAITP 455
TEP +V P + P P + P
Sbjct: 9860 KEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAP 9892
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 60.5 bits (145), Expect = 7e-09
Identities = 55/208 (26%), Positives = 87/208 (41%), Gaps = 35/208 (16%)
Query: 486 TEVTGPPT-------KLESSQDSLVQSETAPEEQKASTSTNICE-LCTCGDETLSCVGLS 537
T+ +GP + +++ S+ S A + S+ C +CTC + + C G
Sbjct: 240 TQCSGPASLRGLNVAEVQKSEFSCSGQGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRG-- 297
Query: 538 PKQRLRQVPVPEPDTYNGIFTTLN--------------------FQGNYISYLDGNVWKA 577
+ L +P P+T I LN N I+ + + ++
Sbjct: 298 --KGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG 355
Query: 578 YSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCN 637
L+L N +T+LP+ F GL LQ L L+ NKI I F+ L L ++L N
Sbjct: 356 LRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDN 415
Query: 638 LITKLSLGTFQAWHGMQFLHNLILNRNP 665
I L+ GTF + +Q LH L +NP
Sbjct: 416 KIQSLAKGTFTSLRAIQTLH---LAQNP 440
Score = 55.8 bits (133), Expect = 2e-07
Identities = 50/184 (27%), Positives = 77/184 (41%), Gaps = 19/184 (10%)
Query: 523 LCTCGDETLSCVGLSPKQRLRQVPV-PEPDTYNGIFTT---------------LNFQGNY 566
LCTC T+ C G + + +P E NG T L N
Sbjct: 37 LCTCTGTTVDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQ 96
Query: 567 ISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESL 626
I ++ + E+L L+ N L LP+ F+ L LDLS N I+ I R+ F
Sbjct: 97 IGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGA 156
Query: 627 PFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMG 686
L+ + L N I+ + G F+A G++ L LN N +TT+ +P L+ +
Sbjct: 157 TDLKNLQLDKNQISCIEEGAFRALRGLEV---LTLNNNNITTIPVSSFNHMPKLRTFRLH 213
Query: 687 TTHI 690
+ H+
Sbjct: 214 SNHL 217
Score = 42.0 bits (97), Expect = 0.003
Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 3/106 (2%)
Query: 560 LNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIE 619
+N N +S ++ ++ + +L L+ N L + F GL L+ L L N+I I
Sbjct: 570 INLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIH 629
Query: 620 RQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNP 665
+F L ++ ++L N IT +S G F +Q L L L NP
Sbjct: 630 NDSFTGLRNVRLLSLYDNQITTVSPGAFDT---LQSLSTLNLLANP 672
Score = 40.0 bits (92), Expect = 0.010
Identities = 36/141 (25%), Positives = 63/141 (44%), Gaps = 5/141 (3%)
Query: 581 TEKLILSENYLTELPKDS-FEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLI 639
T +L L+ N ++ L F+ L +L+ ++LS NK+ IE FE + ++L N +
Sbjct: 542 TAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQL 601
Query: 640 TKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNIL 699
+ G F+ G+ L L+L N ++ + + L ++ L + IT T
Sbjct: 602 ESIRSGMFR---GLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQIT-TVSPGAF 657
Query: 700 TMTVELEKLILPSHMACCLCQ 720
L L L ++ C CQ
Sbjct: 658 DTLQSLSTLNLLANPFNCNCQ 678
Score = 39.3 bits (90), Expect = 0.018
Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 4/104 (3%)
Query: 583 KLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKL 642
+L L N T +P YLQ +DLS NKI + +F ++ L + L N + +
Sbjct: 765 ELYLDGNQFTLVP-GQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCI 823
Query: 643 SLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMG 686
FQ G++ L L L+ N ++T+++ ++ +L +L +G
Sbjct: 824 PPLAFQ---GLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIG 864
Score = 37.4 bits (85), Expect = 0.067
Identities = 24/78 (30%), Positives = 38/78 (48%)
Query: 560 LNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIE 619
++ N IS L + + S LILS N L +P +F+GL L+ L L N I ++
Sbjct: 789 VDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQ 848
Query: 620 RQTFESLPFLQYINLGCN 637
F + L ++ +G N
Sbjct: 849 EGIFADVTSLSHLAIGAN 866
>gi|221136985 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 60.1 bits (144), Expect = 1e-08
Identities = 68/260 (26%), Positives = 116/260 (44%), Gaps = 26/260 (10%)
Query: 510 EEQKASTSTNICEL-CTCGDETLSCVGLSPKQR-LRQVPVPEPDTYNGIFTTLNFQGNYI 567
+ + T+ +IC++ C C +E + + ++ + + V + +P Y LN GN +
Sbjct: 18 QTESRKTAKDICKIRCLC-EEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLN--GNLL 74
Query: 568 SYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLP 627
+ L N + YS L L N L E+ +F GL L+ L L+ NK+ + TF L
Sbjct: 75 TRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLE 134
Query: 628 FLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGT 687
L+Y+ N I+ + G F + L LILN N L ++ +F L +LD+
Sbjct: 135 SLEYLQADYNYISAIEAGAFSK---LNKLKVLILNDNLLLSLPS-NVFRFVLLTHLDLRG 190
Query: 688 THITLTTLKNIL-----TMTVELEKLILPSHMACCLCQFKNSI--------EAVCKT-VK 733
+ + +L M ++LE+ P + C L K + E VC+T +
Sbjct: 191 NRLKVMPFAGVLEHIGGIMEIQLEE--NPWNCTCDLLPLKAWLDTITVFVGEIVCETPFR 248
Query: 734 LH-CNTACLTNSIHCPEEAS 752
LH + LT CP +++
Sbjct: 249 LHGKDVTQLTRQDLCPRKSA 268
Score = 58.9 bits (141), Expect = 2e-08
Identities = 68/291 (23%), Positives = 115/291 (39%), Gaps = 25/291 (8%)
Query: 466 ALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTSTNICELCT 525
AL TRAP + + P ++ S+D + K+ C
Sbjct: 292 ALNPTRAPKASRPPKMRNR------PTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCV 345
Query: 526 CGDETLSCVGLSPKQRLRQVP-----VPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSW 580
C ++ S GL+ + R+ P+P + ++ T GNY+ + N YS
Sbjct: 346 CTSQS-SDNGLNVNCQERKFTNISDLQPKPTSPKKLYLT----GNYLQTVYKNDLLEYSS 400
Query: 581 TEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLIT 640
+ L L N + + + +F L L+ L L+ N + + F+ L LQY+ L N+I
Sbjct: 401 LDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIK 460
Query: 641 KLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILT 700
++ TF A +Q L LN N L ++ D +F AL L++ H + +K +L
Sbjct: 461 EIKPLTFDALINLQL---LFLNNNLLRSLPD-NIFGGTALTRLNLRNNHFSHLPVKGVLD 516
Query: 701 MTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEEA 751
++ L + C C K H N+ + N + C A
Sbjct: 517 QLPAFIQIDLQENPWDCTCDIMG-----LKDWTEHANSPVIINEVTCESPA 562
>gi|221136981 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 60.1 bits (144), Expect = 1e-08
Identities = 68/260 (26%), Positives = 116/260 (44%), Gaps = 26/260 (10%)
Query: 510 EEQKASTSTNICEL-CTCGDETLSCVGLSPKQR-LRQVPVPEPDTYNGIFTTLNFQGNYI 567
+ + T+ +IC++ C C +E + + ++ + + V + +P Y LN GN +
Sbjct: 18 QTESRKTAKDICKIRCLC-EEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLN--GNLL 74
Query: 568 SYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLP 627
+ L N + YS L L N L E+ +F GL L+ L L+ NK+ + TF L
Sbjct: 75 TRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLE 134
Query: 628 FLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGT 687
L+Y+ N I+ + G F + L LILN N L ++ +F L +LD+
Sbjct: 135 SLEYLQADYNYISAIEAGAFSK---LNKLKVLILNDNLLLSLPS-NVFRFVLLTHLDLRG 190
Query: 688 THITLTTLKNIL-----TMTVELEKLILPSHMACCLCQFKNSI--------EAVCKT-VK 733
+ + +L M ++LE+ P + C L K + E VC+T +
Sbjct: 191 NRLKVMPFAGVLEHIGGIMEIQLEE--NPWNCTCDLLPLKAWLDTITVFVGEIVCETPFR 248
Query: 734 LH-CNTACLTNSIHCPEEAS 752
LH + LT CP +++
Sbjct: 249 LHGKDVTQLTRQDLCPRKSA 268
Score = 58.9 bits (141), Expect = 2e-08
Identities = 68/291 (23%), Positives = 115/291 (39%), Gaps = 25/291 (8%)
Query: 466 ALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTSTNICELCT 525
AL TRAP + + P ++ S+D + K+ C
Sbjct: 292 ALNPTRAPKASRPPKMRNR------PTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCV 345
Query: 526 CGDETLSCVGLSPKQRLRQVP-----VPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSW 580
C ++ S GL+ + R+ P+P + ++ T GNY+ + N YS
Sbjct: 346 CTSQS-SDNGLNVNCQERKFTNISDLQPKPTSPKKLYLT----GNYLQTVYKNDLLEYSS 400
Query: 581 TEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLIT 640
+ L L N + + + +F L L+ L L+ N + + F+ L LQY+ L N+I
Sbjct: 401 LDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIK 460
Query: 641 KLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILT 700
++ TF A +Q L LN N L ++ D +F AL L++ H + +K +L
Sbjct: 461 EIKPLTFDALINLQL---LFLNNNLLRSLPD-NIFGGTALTRLNLRNNHFSHLPVKGVLD 516
Query: 701 MTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEEA 751
++ L + C C K H N+ + N + C A
Sbjct: 517 QLPAFIQIDLQENPWDCTCDIMG-----LKDWTEHANSPVIINEVTCESPA 562
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,386,824
Number of Sequences: 37866
Number of extensions: 2419066
Number of successful extensions: 15658
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 192
Number of HSP's successfully gapped in prelim test: 795
Number of HSP's that attempted gapping in prelim test: 10824
Number of HSP's gapped (non-prelim): 3700
length of query: 947
length of database: 18,247,518
effective HSP length: 112
effective length of query: 835
effective length of database: 14,006,526
effective search space: 11695449210
effective search space used: 11695449210
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.