Search of human proteins with 5174741

Search of human proteins with 5174741

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5174741 ubiquitin carboxyl-terminal esterase L3 [Homo
sapiens]
         (230 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5174741 ubiquitin carboxyl-terminal esterase L3 [Homo sapiens]     468   e-132
gi|21361091 ubiquitin carboxyl-terminal esterase L1 [Homo sapiens]    258   3e-69
gi|7706753 ubiquitin carboxyl-terminal hydrolase L5 [Homo sapiens]     85   5e-17
gi|4757836 BRCA1 associated protein-1 [Homo sapiens]                   69   4e-12
gi|157688564 diacylglycerol kinase zeta isoform 4 [Homo sapiens]       30   1.3  
gi|41872522 diacylglycerol kinase zeta isoform 1 [Homo sapiens]        30   1.3  
gi|41872507 diacylglycerol kinase zeta isoform 2 [Homo sapiens]        30   1.3  
gi|41872527 diacylglycerol kinase zeta isoform 3 [Homo sapiens]        30   1.3  
gi|13376768 elongation factor RNA polymerase II-like 3 [Homo sap...    28   5.0  
gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens]                   28   8.6  

>gi|5174741 ubiquitin carboxyl-terminal esterase L3 [Homo sapiens]
          Length = 230

 Score =  468 bits (1203), Expect = e-132
 Identities = 230/230 (100%), Positives = 230/230 (100%)

Query: 1   MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITE 60
           MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITE
Sbjct: 1   MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITE 60

Query: 61  KYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLK 120
           KYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLK
Sbjct: 61  KYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLK 120

Query: 121 KFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHL 180
           KFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHL
Sbjct: 121 KFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHL 180

Query: 181 YELDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA 230
           YELDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA
Sbjct: 181 YELDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA 230


>gi|21361091 ubiquitin carboxyl-terminal esterase L1 [Homo sapiens]
          Length = 223

 Score =  258 bits (659), Expect = 3e-69
 Identities = 123/223 (55%), Positives = 168/223 (75%), Gaps = 5/223 (2%)

Query: 8   PLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRT 67
           P+E NPE+ N+ L +LG+   W+FVDV G++ E L  VP P CA+LLLFP+T ++E FR 
Sbjct: 5   PMEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRK 64

Query: 68  EEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESV 127
           ++ E++K  GQ+V+  VYFMKQTI N+CGTIGLIHA+ANN+DK+ FE GS LK+FL E+ 
Sbjct: 65  KQIEELK--GQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSETE 122

Query: 128 SMSPEERARYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRK 187
            MSPE+RA+  E  +AI+  H+  A EGQ     +D+KV+ HFI   +VDGHLYELDGR 
Sbjct: 123 KMSPEDRAKCFEKNEAIQAAHDAVAQEGQCR---VDDKVNFHFILFNNVDGHLYELDGRM 179

Query: 188 PFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA 230
           PFP+NHG +S++TLL+DA +VC++F ER+  E+RF+A+AL  A
Sbjct: 180 PFPVNHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALCKA 222


>gi|7706753 ubiquitin carboxyl-terminal hydrolase L5 [Homo sapiens]
          Length = 329

 Score = 85.1 bits (209), Expect = 5e-17
 Identities = 67/228 (29%), Positives = 111/228 (48%), Gaps = 18/228 (7%)

Query: 6   WLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVF 65
           W  +E++P V  + +K  G     Q  +++ ++PE    + +PV  ++ LF    K++  
Sbjct: 8   WCLMESDPGVFTELIKGFGCR-GAQVEEIWSLEPENFEKL-KPVHGLIFLF----KWQ-- 59

Query: 66  RTEEEEKIKSQGQDVT-SSVYFMKQTISNACGTIGLIHAIAN-NKDKMHFESGSTLKKFL 123
               EE   S  QD    +++F KQ I+NAC T  ++  + N     +H   G TL +F 
Sbjct: 60  --PGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHL--GETLSEFK 115

Query: 124 EESVSMSPEERARYLENYDAIRVTHETSAHEGQTE---APSIDEKVDLHFIALVHVDGHL 180
           E S S     +   L N D IR  H + A +   E     S  E+   HF++ V V+G L
Sbjct: 116 EFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRL 175

Query: 181 YELDGRKPFPINHGETSDETLLEDAIEVCKKFMER-DPDELRFNAIAL 227
           YELDG +  PI+ G  + +  +     V +K +++    E+RFN +A+
Sbjct: 176 YELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAI 223


>gi|4757836 BRCA1 associated protein-1 [Homo sapiens]
          Length = 729

 Score = 68.6 bits (166), Expect = 4e-12
 Identities = 59/239 (24%), Positives = 104/239 (43%), Gaps = 27/239 (11%)

Query: 6   WLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVF 65
           WL LE++P +    ++  G+    Q  ++Y    +L S    PV   + LF   E+    
Sbjct: 5   WLELESDPGLFTLLVEDFGVK-GVQVEEIY----DLQSKCQGPVYGFIFLFKWIEERRSR 59

Query: 66  RTEEE--EKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFL 123
           R      +       D+ ++++F  Q I N+C T  L+  + N       + G TL +  
Sbjct: 60  RKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSS---VDLGPTLSRMK 116

Query: 124 EESVSMSPEERARYLENYDAIRVTHETSAH-------EGQTEAPSIDEKVDLHFIALVHV 176
           + +   SPE +   + N   +   H + A        E Q    ++      HF++ V +
Sbjct: 117 DFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPI 176

Query: 177 DGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMER-------DP-DELRFNAIAL 227
            G L+ELDG K +PI+HG   ++    D  +  +  MER       +P  ++RFN +A+
Sbjct: 177 TGRLFELDGLKVYPIDHGPWGEDEEWTD--KARRVIMERIGLATAGEPYHDIRFNLMAV 233


>gi|157688564 diacylglycerol kinase zeta isoform 4 [Homo sapiens]
          Length = 1117

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 42/186 (22%), Positives = 73/186 (39%), Gaps = 31/186 (16%)

Query: 33   DVYGMDPELLSMVPRP-VCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSV----YFM 87
            ++Y +DPELL    RP +       P +      R+ + +    QG+++  +     +  
Sbjct: 935  EIYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCK 994

Query: 88   KQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYL------ENY 141
             Q +  A G            D MH +  S  +  L  +VS   ++  RYL      E  
Sbjct: 995  LQELHRAGG------------DLMHRDEQS--RTLLHHAVSTGSKDVVRYLLDHAPPEIL 1040

Query: 142  DAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETL 201
            DA+    ET  H    +A ++ ++   H+I  V     L + D +   P    E + +T 
Sbjct: 1041 DAVEENGETCLH----QAAALGQRTICHYI--VEAGASLMKTDQQGDTPRQRAEKAQDTE 1094

Query: 202  LEDAIE 207
            L   +E
Sbjct: 1095 LAAYLE 1100


>gi|41872522 diacylglycerol kinase zeta isoform 1 [Homo sapiens]
          Length = 945

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 42/186 (22%), Positives = 73/186 (39%), Gaps = 31/186 (16%)

Query: 33  DVYGMDPELLSMVPRP-VCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSV----YFM 87
           ++Y +DPELL    RP +       P +      R+ + +    QG+++  +     +  
Sbjct: 763 EIYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCK 822

Query: 88  KQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYL------ENY 141
            Q +  A G            D MH +  S  +  L  +VS   ++  RYL      E  
Sbjct: 823 LQELHRAGG------------DLMHRDEQS--RTLLHHAVSTGSKDVVRYLLDHAPPEIL 868

Query: 142 DAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETL 201
           DA+    ET  H    +A ++ ++   H+I  V     L + D +   P    E + +T 
Sbjct: 869 DAVEENGETCLH----QAAALGQRTICHYI--VEAGASLMKTDQQGDTPRQRAEKAQDTE 922

Query: 202 LEDAIE 207
           L   +E
Sbjct: 923 LAAYLE 928


>gi|41872507 diacylglycerol kinase zeta isoform 2 [Homo sapiens]
          Length = 929

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 42/186 (22%), Positives = 73/186 (39%), Gaps = 31/186 (16%)

Query: 33  DVYGMDPELLSMVPRP-VCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSV----YFM 87
           ++Y +DPELL    RP +       P +      R+ + +    QG+++  +     +  
Sbjct: 747 EIYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCK 806

Query: 88  KQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYL------ENY 141
            Q +  A G            D MH +  S  +  L  +VS   ++  RYL      E  
Sbjct: 807 LQELHRAGG------------DLMHRDEQS--RTLLHHAVSTGSKDVVRYLLDHAPPEIL 852

Query: 142 DAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETL 201
           DA+    ET  H    +A ++ ++   H+I  V     L + D +   P    E + +T 
Sbjct: 853 DAVEENGETCLH----QAAALGQRTICHYI--VEAGASLMKTDQQGDTPRQRAEKAQDTE 906

Query: 202 LEDAIE 207
           L   +E
Sbjct: 907 LAAYLE 912


>gi|41872527 diacylglycerol kinase zeta isoform 3 [Homo sapiens]
          Length = 895

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 42/186 (22%), Positives = 73/186 (39%), Gaps = 31/186 (16%)

Query: 33  DVYGMDPELLSMVPRP-VCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSV----YFM 87
           ++Y +DPELL    RP +       P +      R+ + +    QG+++  +     +  
Sbjct: 713 EIYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCK 772

Query: 88  KQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYL------ENY 141
            Q +  A G            D MH +  S  +  L  +VS   ++  RYL      E  
Sbjct: 773 LQELHRAGG------------DLMHRDEQS--RTLLHHAVSTGSKDVVRYLLDHAPPEIL 818

Query: 142 DAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETL 201
           DA+    ET  H    +A ++ ++   H+I  V     L + D +   P    E + +T 
Sbjct: 819 DAVEENGETCLH----QAAALGQRTICHYI--VEAGASLMKTDQQGDTPRQRAEKAQDTE 872

Query: 202 LEDAIE 207
           L   +E
Sbjct: 873 LAAYLE 878


>gi|13376768 elongation factor RNA polymerase II-like 3 [Homo
           sapiens]
          Length = 397

 Score = 28.5 bits (62), Expect = 5.0
 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 3/94 (3%)

Query: 124 EESVSMSPEERARYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYEL 183
           E+S S SPE+   YL  Y AI    +  A+E   E    + ++ LH  A V      +  
Sbjct: 274 EDSESPSPEDIPDYLLQYRAIHSAEQQHAYEQDFETDYAEYRI-LH--ARVGTASQRFIE 330

Query: 184 DGRKPFPINHGETSDETLLEDAIEVCKKFMERDP 217
            G +   +  G    + L +  I+  KKF ++ P
Sbjct: 331 LGAEIKRVRRGTPEYKVLEDKIIQEYKKFRKQYP 364


>gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens]
          Length = 1079

 Score = 27.7 bits (60), Expect = 8.6
 Identities = 29/142 (20%), Positives = 54/142 (38%), Gaps = 25/142 (17%)

Query: 58  ITEKYEVFRTEEEEKIKSQGQD-----VTSSVYFMKQTISNACGTIGLIHAIANNKDKMH 112
           + E  E  R   E +I  + Q       T  + + K+T+ N   T+           + H
Sbjct: 34  LLEALEELRMRREAEIHYEEQIGKIIVETQELKWQKETLQNQKETLA----------EQH 83

Query: 113 FESGSTLKKFLEESVSMSPEERARY----------LENYDAIRVTHETSAHEGQTEAPSI 162
            E+ +  KK L+  +    EE+ +Y          +E         + S +  Q +   +
Sbjct: 84  KEAMAVFKKQLQMKMCALEEEKGKYQLATEIKEKEIEGLKETLKALQVSKYSLQKKVSEM 143

Query: 163 DEKVDLHFIALVHVDGHLYELD 184
           ++KV LH +A       L E++
Sbjct: 144 EQKVQLHLLAKEDYHKQLSEIE 165


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,865,744
Number of Sequences: 37866
Number of extensions: 395207
Number of successful extensions: 1065
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1058
Number of HSP's gapped (non-prelim): 10
length of query: 230
length of database: 18,247,518
effective HSP length: 99
effective length of query: 131
effective length of database: 14,498,784
effective search space: 1899340704
effective search space used: 1899340704
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.