BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|13376331 L-2-hydroxyglutarate dehydrogenase precursor [Homo sapiens] (463 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|13376331 L-2-hydroxyglutarate dehydrogenase precursor [Homo s... 931 0.0 gi|194306651 pyruvate dehydrogenase phosphatase regulatory subun... 47 3e-05 gi|197927446 sarcosine dehydrogenase precursor [Homo sapiens] 47 4e-05 gi|21361378 sarcosine dehydrogenase precursor [Homo sapiens] 47 4e-05 gi|8923708 FAD-dependent oxidoreductase domain containing 1 [Hom... 36 0.065 gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial... 35 0.14 gi|133908614 glycerol-3-phosphate dehydrogenase 2, mitochondrial... 35 0.14 gi|24797151 dimethylglycine dehydrogenase precursor [Homo sapiens] 32 0.93 gi|4557735 monoamine oxidase A [Homo sapiens] 31 2.1 gi|153252198 septin 14 [Homo sapiens] 31 2.1 gi|38202207 monoamine oxidase B [Homo sapiens] 31 2.7 gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens] 30 3.5 gi|192807292 keratin 24 [Homo sapiens] 30 4.6 gi|50301238 glutathione reductase [Homo sapiens] 30 4.6 gi|116325985 transcript expressed during hematopoiesis 2 [Homo s... 30 6.0 gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 30 6.0 gi|32967305 coenzyme Q6 homolog isoform a [Homo sapiens] 29 7.9 >gi|13376331 L-2-hydroxyglutarate dehydrogenase precursor [Homo sapiens] Length = 463 Score = 931 bits (2405), Expect = 0.0 Identities = 463/463 (100%), Positives = 463/463 (100%) Query: 1 MVPALRYLVGACGRARGLFAGGSPGACGFASGRPRPLCGGSRSASTSSFDIVIVGGGIVG 60 MVPALRYLVGACGRARGLFAGGSPGACGFASGRPRPLCGGSRSASTSSFDIVIVGGGIVG Sbjct: 1 MVPALRYLVGACGRARGLFAGGSPGACGFASGRPRPLCGGSRSASTSSFDIVIVGGGIVG 60 Query: 61 LASARALILRHPSLSIGVLEKEKDLAVHQTGHNSGVIHSGIYYKPESLKAKLCVQGAALL 120 LASARALILRHPSLSIGVLEKEKDLAVHQTGHNSGVIHSGIYYKPESLKAKLCVQGAALL Sbjct: 61 LASARALILRHPSLSIGVLEKEKDLAVHQTGHNSGVIHSGIYYKPESLKAKLCVQGAALL 120 Query: 121 YEYCQQKGISYKQCGKLIVAVEQEEIPRLQALYEKGLQNGVPGLRLIQQEDIKKKEPYCR 180 YEYCQQKGISYKQCGKLIVAVEQEEIPRLQALYEKGLQNGVPGLRLIQQEDIKKKEPYCR Sbjct: 121 YEYCQQKGISYKQCGKLIVAVEQEEIPRLQALYEKGLQNGVPGLRLIQQEDIKKKEPYCR 180 Query: 181 GLMAIDCPHTGIVDYRQVALSFAQDFQEAGGSVLTNFEVKGIEMAKESPSRSIDGMQYPI 240 GLMAIDCPHTGIVDYRQVALSFAQDFQEAGGSVLTNFEVKGIEMAKESPSRSIDGMQYPI Sbjct: 181 GLMAIDCPHTGIVDYRQVALSFAQDFQEAGGSVLTNFEVKGIEMAKESPSRSIDGMQYPI 240 Query: 241 VIKNTKGEEIRCQYVVTCAGLYSDRISELSGCTPDPRIVPFRGDYLLLKPEKCYLVKGNI 300 VIKNTKGEEIRCQYVVTCAGLYSDRISELSGCTPDPRIVPFRGDYLLLKPEKCYLVKGNI Sbjct: 241 VIKNTKGEEIRCQYVVTCAGLYSDRISELSGCTPDPRIVPFRGDYLLLKPEKCYLVKGNI 300 Query: 301 YPVPDSRFPFLGVHFTPRMDGSIWLGPNAVLAFKREGYRPFDFSATDVMDIIINSGLIKL 360 YPVPDSRFPFLGVHFTPRMDGSIWLGPNAVLAFKREGYRPFDFSATDVMDIIINSGLIKL Sbjct: 301 YPVPDSRFPFLGVHFTPRMDGSIWLGPNAVLAFKREGYRPFDFSATDVMDIIINSGLIKL 360 Query: 361 ASQNFSYGVTEMYKACFLGATVKYLQKFIPEITISDILRGPAGVRAQALDRDGNLVEDFV 420 ASQNFSYGVTEMYKACFLGATVKYLQKFIPEITISDILRGPAGVRAQALDRDGNLVEDFV Sbjct: 361 ASQNFSYGVTEMYKACFLGATVKYLQKFIPEITISDILRGPAGVRAQALDRDGNLVEDFV 420 Query: 421 FDAGVGDIGNRILHVRNAPSPAATSSIAISGMIADEVQQRFEL 463 FDAGVGDIGNRILHVRNAPSPAATSSIAISGMIADEVQQRFEL Sbjct: 421 FDAGVGDIGNRILHVRNAPSPAATSSIAISGMIADEVQQRFEL 463 >gi|194306651 pyruvate dehydrogenase phosphatase regulatory subunit [Homo sapiens] Length = 879 Score = 47.4 bits (111), Expect = 3e-05 Identities = 70/292 (23%), Positives = 121/292 (41%), Gaps = 34/292 (11%) Query: 8 LVGACGRARGLFAGGSPGACGFASGRPRPLCGGSRS-ASTSSFDIVIVGGGIVGLASARA 66 L+ GR R SPG ++S R +RS A + +VI GGGI G + A Sbjct: 6 LLSIVGRQRA-----SPGWQNWSSARNSTSAAEARSMALPTQAQVVICGGGITGTSVAYH 60 Query: 67 LILRHPSLSIGVLEKEKDLAVHQTGHNSGVIHSGIYYKPESLKAKLCVQGAALLYEYCQQ 126 L + I +LE+ + LA T +G++ + + +++ K+ L Y+ Q+ Sbjct: 61 LS-KMGWKDIVLLEQGR-LAAGSTRFCAGILSTARHL---TIEQKMADYSNKLYYQLEQE 115 Query: 127 KGIS--YKQCGKLIVAVEQEEIPRLQALYEKGLQNGVPGLRLIQQEDIKKKEPYCRG--- 181 GI Y + G + +A Q+ + L+ + G+P +I + + + Sbjct: 116 TGIQTGYTRTGSIFLAQTQDRLISLKRINAGLNVIGIPS-EIISPKKVAELHHLLNVHDL 174 Query: 182 LMAIDCPHTGIVDYRQVALSFAQDFQEAGGSVLTNFEVKGIEMAKESPSRSIDGMQYPIV 241 + A+ P +V VAL+ A + G + V + + K + Sbjct: 175 VGAMHVPEDAVVSSADVALALASAASQNGVQIYDRTSVLHVMVKKGQVTG---------- 224 Query: 242 IKNTKGEEIRCQYVVTCAGLYSDRISELSGCTPDPRIVPFRG---DYLLLKP 290 ++ KG+ I CQY V CAG ++ EL +P +P YLL +P Sbjct: 225 VETDKGQ-IECQYFVNCAGQWA---YELGLSNEEPVSIPLHACEHFYLLTRP 272 >gi|197927446 sarcosine dehydrogenase precursor [Homo sapiens] Length = 918 Score = 47.0 bits (110), Expect = 4e-05 Identities = 59/258 (22%), Positives = 110/258 (42%), Gaps = 36/258 (13%) Query: 25 GACGFASGRPRPLCGGSRSASTSSFDIVIVGGGIVGLASARALILRHPSLSIGVLEKEKD 84 G A G RPL S+ ++V++GGG +G + L S ++ +LE+E+ Sbjct: 51 GTSVVAQGPSRPL--------PSTANVVVIGGGSLGCQTLYHLAKLGMSGAV-LLERER- 100 Query: 85 LAVHQTGHNSGVIHSGIYYKPESLKAKLCVQGAALLY-EYCQQKGI--SYKQCGKLIVAV 141 L T H +G++ +P ++ +L ++ E ++ G+ + Q G L +A Sbjct: 101 LTSGTTWHTAGLLWQ---LRPSDVEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIAS 157 Query: 142 EQEEIPRLQALYEKGLQNGVPGLRLIQQEDIKKKEPYCRGLMAID-------CPHTGIVD 194 ++ + + L G GV ++ + K P LM +D PH G +D Sbjct: 158 NRQRLDEYKRLMSLGKAYGVES-HVLSPAETKTLYP----LMNVDDLYGTLYVPHDGTMD 212 Query: 195 YRQVALSFAQDFQEAGGSVLTNFEVKGIEM-AKESPSRSIDGMQYPIVIKNTKGEEIRCQ 253 + A+ G V+ N V GI + + R + G++ T+ I+ Sbjct: 213 PAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVRRVAGVE-------TQHGSIQTP 265 Query: 254 YVVTCAGLYSDRISELSG 271 VV CAG+++ + ++G Sbjct: 266 CVVNCAGVWASAVGRMAG 283 >gi|21361378 sarcosine dehydrogenase precursor [Homo sapiens] Length = 918 Score = 47.0 bits (110), Expect = 4e-05 Identities = 59/258 (22%), Positives = 110/258 (42%), Gaps = 36/258 (13%) Query: 25 GACGFASGRPRPLCGGSRSASTSSFDIVIVGGGIVGLASARALILRHPSLSIGVLEKEKD 84 G A G RPL S+ ++V++GGG +G + L S ++ +LE+E+ Sbjct: 51 GTSVVAQGPSRPL--------PSTANVVVIGGGSLGCQTLYHLAKLGMSGAV-LLERER- 100 Query: 85 LAVHQTGHNSGVIHSGIYYKPESLKAKLCVQGAALLY-EYCQQKGI--SYKQCGKLIVAV 141 L T H +G++ +P ++ +L ++ E ++ G+ + Q G L +A Sbjct: 101 LTSGTTWHTAGLLWQ---LRPSDVEVELLAHTRRVVSRELEEETGLHTGWIQNGGLFIAS 157 Query: 142 EQEEIPRLQALYEKGLQNGVPGLRLIQQEDIKKKEPYCRGLMAID-------CPHTGIVD 194 ++ + + L G GV ++ + K P LM +D PH G +D Sbjct: 158 NRQRLDEYKRLMSLGKAYGVES-HVLSPAETKTLYP----LMNVDDLYGTLYVPHDGTMD 212 Query: 195 YRQVALSFAQDFQEAGGSVLTNFEVKGIEM-AKESPSRSIDGMQYPIVIKNTKGEEIRCQ 253 + A+ G V+ N V GI + + R + G++ T+ I+ Sbjct: 213 PAGTCTTLARAASARGAQVIENCPVTGIRVWTDDFGVRRVAGVE-------TQHGSIQTP 265 Query: 254 YVVTCAGLYSDRISELSG 271 VV CAG+++ + ++G Sbjct: 266 CVVNCAGVWASAVGRMAG 283 >gi|8923708 FAD-dependent oxidoreductase domain containing 1 [Homo sapiens] Length = 486 Score = 36.2 bits (82), Expect = 0.065 Identities = 64/301 (21%), Positives = 121/301 (40%), Gaps = 28/301 (9%) Query: 50 DIVIVGGGIVGLASA---RALILRHPSLSIGVLEKEKDLAVHQTGHNSGVIHSGIYYKPE 106 D+VIVGGG++GL+ A + L R ++ + V+E++ + TG + G I + PE Sbjct: 65 DVVIVGGGVLGLSVAYWLKKLESRRGAIRVLVVERDHTYSQASTGLSVGGICQQ-FSLPE 123 Query: 107 SLKAKL-CVQGAALLYEY-----CQQKGISYKQCGKLIVAVEQEEIPRLQALYEKGLQNG 160 +++ L + EY + + G L++A E ++ +++ + Q G Sbjct: 124 NIQLSLFSASFLRNINEYLAVVDAPPLDLRFNPSGYLLLASE-KDAAAMESNVKVQRQEG 182 Query: 161 VPGLRLIQQEDIKKKEPYCR----GLMAIDCPHTGIVDYRQVALSFAQDFQEAG----GS 212 + L+ + ++ K P+ L + G D + + Q G Sbjct: 183 AK-VSLMSPDQLRNKFPWINTEGVALASYGMEDEGWFDPWCLLQGLRRKVQSLGVLFCQG 241 Query: 213 VLTNFEVKGIEMAKESPSRSIDGMQYPIVIKNTKGEE---IRCQYVVTCAGLYSDRISEL 269 +T F M + + + +K + E + C V+ AG +S +I+ L Sbjct: 242 EVTRFVSSSQRMLTTDDKAVVLKRIHEVHVKMDRSLEYQPVECAIVINAAGAWSAQIAAL 301 Query: 270 SGCTPDPRIVPFRGDYLLLKPEKCYLVKGNIYPVPDSRFPFL----GVHFTPRMDGSIWL 325 +G P +G L ++P K Y+ + P P + G +F GS +L Sbjct: 302 AGVGEGPP-GTLQGTKLPVEPRKRYVYVWHCPQGPGLETPLVADTSGAYFRREGLGSNYL 360 Query: 326 G 326 G Sbjct: 361 G 361 >gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial [Homo sapiens] Length = 727 Score = 35.0 bits (79), Expect = 0.14 Identities = 18/64 (28%), Positives = 36/64 (56%), Gaps = 3/64 (4%) Query: 45 STSSFDIVIVGGGIVGLASARALILRHPSLSIGVLEKEKDLAVHQTGHNSGVIHSGIYYK 104 +TS FDI+++GGG G A + R L ++E++ D + + ++ +IH G+ Y Sbjct: 66 NTSEFDILVIGGGATGSGCALDAVTR--GLKTALVERD-DFSSGTSSRSTKLIHGGVRYL 122 Query: 105 PESL 108 +++ Sbjct: 123 QKAI 126 >gi|133908614 glycerol-3-phosphate dehydrogenase 2, mitochondrial [Homo sapiens] Length = 727 Score = 35.0 bits (79), Expect = 0.14 Identities = 18/64 (28%), Positives = 36/64 (56%), Gaps = 3/64 (4%) Query: 45 STSSFDIVIVGGGIVGLASARALILRHPSLSIGVLEKEKDLAVHQTGHNSGVIHSGIYYK 104 +TS FDI+++GGG G A + R L ++E++ D + + ++ +IH G+ Y Sbjct: 66 NTSEFDILVIGGGATGSGCALDAVTR--GLKTALVERD-DFSSGTSSRSTKLIHGGVRYL 122 Query: 105 PESL 108 +++ Sbjct: 123 QKAI 126 >gi|24797151 dimethylglycine dehydrogenase precursor [Homo sapiens] Length = 866 Score = 32.3 bits (72), Expect = 0.93 Identities = 55/271 (20%), Positives = 110/271 (40%), Gaps = 35/271 (12%) Query: 32 GRPRPLCGGSR------SASTSSFD---IVIVGGGIVGLASARALILRHPSLSIGVLEKE 82 GRPR +CG SA T D VI+GGG VG+ + A L + VL ++ Sbjct: 24 GRPRSVCGREGEEKPPLSAETQWKDRAETVIIGGGCVGV--SLAYHLAKAGMKDVVLLEK 81 Query: 83 KDLAVHQTGHNSGVIHSGIYYKPESLKAKLCVQGAALLYEYCQQKG---ISYKQCGKLIV 139 +L T H +G+ Y+ P + K + LYE +++ + + Q G + + Sbjct: 82 SELTAGSTWHAAGLT---TYFHP-GINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRL 137 Query: 140 AVEQEEIPRLQALYEKGLQNGVPGLRLIQQEDIKKKEPYC---RGLMAIDCPHTGIVDYR 196 A + + + + LI+ E I++ P + L + P G +D Sbjct: 138 ATTPVRVDEFKYQMTRTGWHATEQY-LIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPY 196 Query: 197 QVALSFAQDFQEAGGSVLTNFEVKGIEMAKESPSRSIDGMQYPIVIKNTKGEEIRCQYVV 256 + ++ A ++ G + V ++ A+ + ++ T +R +V Sbjct: 197 SLTMALAAGARKCGALLKYPAPVTSLK-ARSDGTWDVE----------TPQGSMRANRIV 245 Query: 257 TCAGLYSDRISELSGCTPDPRIVPFRGDYLL 287 AG ++ + ++ G + ++P + Y++ Sbjct: 246 NAAGFWAREVGKMIGL--EHPLIPVQHQYVV 274 >gi|4557735 monoamine oxidase A [Homo sapiens] Length = 527 Score = 31.2 bits (69), Expect = 2.1 Identities = 15/32 (46%), Positives = 24/32 (75%), Gaps = 2/32 (6%) Query: 49 FDIVIVGGGIVGLASARALILRHPSLSIGVLE 80 FD+V++GGGI GL++A+ +L +S+ VLE Sbjct: 14 FDVVVIGGGISGLSAAK--LLTEYGVSVLVLE 43 >gi|153252198 septin 14 [Homo sapiens] Length = 432 Score = 31.2 bits (69), Expect = 2.1 Identities = 20/56 (35%), Positives = 34/56 (60%), Gaps = 4/56 (7%) Query: 121 YEYCQQKGISYKQCGKLIVAVEQEEIPRLQALYEKGLQNGVPGLRLIQQEDIKKKE 176 Y+ CQ++ KQ + + V+++E +A EK LQ+ L++IQQE+I+K E Sbjct: 342 YDQCQREEEELKQ--RFMQRVKEKEATFKEA--EKELQDKFEHLKMIQQEEIRKLE 393 >gi|38202207 monoamine oxidase B [Homo sapiens] Length = 520 Score = 30.8 bits (68), Expect = 2.7 Identities = 15/31 (48%), Positives = 23/31 (74%), Gaps = 2/31 (6%) Query: 50 DIVIVGGGIVGLASARALILRHPSLSIGVLE 80 D+V+VGGGI G+A+A+ +L L++ VLE Sbjct: 6 DVVVVGGGISGMAAAK--LLHDSGLNVVVLE 34 >gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens] Length = 610 Score = 30.4 bits (67), Expect = 3.5 Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 17/115 (14%) Query: 4 ALRYLVGACGRARGLFAGGSPGACGFASGRP-RPLCGG------------SRSASTSSFD 50 A+ L C GLF+G SP RP PL S + D Sbjct: 10 AVLLLAVLCKVYLGLFSGSSPNPFSEDVKRPPAPLVTDKEARKKVLKQAFSANQVPEKLD 69 Query: 51 IVIVGGGIVGLASARALILRHPSLSIGVLEKEKDL--AVHQTGHNSGVIHSGIYY 103 +V++G G GLA+ A IL + VLE+ H G N +GI+Y Sbjct: 70 VVVIGSGFGGLAA--AAILAKAGKRVLVLEQHTKAGGCCHTFGKNGLEFDTGIHY 122 >gi|192807292 keratin 24 [Homo sapiens] Length = 525 Score = 30.0 bits (66), Expect = 4.6 Identities = 22/53 (41%), Positives = 26/53 (49%), Gaps = 5/53 (9%) Query: 10 GACGRARGLFAGGSP--GACGFASGRPRPLCGGSRSASTSSFDIVIVGGGIVG 60 GA G G F GGS G GF GR CG SR +S ++ GGG+ G Sbjct: 79 GASGSGTG-FGGGSSFGGVSGF--GRGSGFCGSSRFSSGATGGFYSYGGGMGG 128 >gi|50301238 glutathione reductase [Homo sapiens] Length = 522 Score = 30.0 bits (66), Expect = 4.6 Identities = 13/32 (40%), Positives = 21/32 (65%) Query: 34 PRPLCGGSRSASTSSFDIVIVGGGIVGLASAR 65 P+P + + +S+D +++GGG GLASAR Sbjct: 50 PQPQGPPPAAGAVASYDYLVIGGGSGGLASAR 81 >gi|116325985 transcript expressed during hematopoiesis 2 [Homo sapiens] Length = 113 Score = 29.6 bits (65), Expect = 6.0 Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 7/78 (8%) Query: 315 FTPRMDGSIWLGPNAVLAFKREGYRPFDFSATDVMDIIINSGLIK-LASQNFSYGVTEMY 373 FT R++G AVL ++ G R D T+V D G+ K LA + V E Sbjct: 30 FTVRLNGC---HDRAVLLYEYVGKRIVDLQHTEVPDAYRGRGIAKHLAKAALDFVVEEDL 86 Query: 374 KACFLGATVKYLQKFIPE 391 KA T Y+QK++ E Sbjct: 87 KA---HLTCWYIQKYVKE 101 >gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] Length = 753 Score = 29.6 bits (65), Expect = 6.0 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 3/66 (4%) Query: 2 VPALRYLVGACGR---ARGLFAGGSPGACGFASGRPRPLCGGSRSASTSSFDIVIVGGGI 58 VP++R G+ AR G GA G +SG+PR G + +A+TS++ G GI Sbjct: 51 VPSVRSCALGAGQEQLARAAQPVGPLGAAGRSSGKPRQPTGAAAAAATSTWSRGPRGLGI 110 Query: 59 VGLASA 64 A A Sbjct: 111 PDQACA 116 >gi|32967305 coenzyme Q6 homolog isoform a [Homo sapiens] Length = 468 Score = 29.3 bits (64), Expect = 7.9 Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 5/46 (10%) Query: 27 CGFASGRPR--PLCGGSRSASTSS---FDIVIVGGGIVGLASARAL 67 CG P PL R + S+ +D+V+ GGG+VG A A AL Sbjct: 9 CGAVRAAPHSGPLVSWRRWSGASTDTVYDVVVSGGGLVGAAMACAL 54 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.140 0.420 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,181,578 Number of Sequences: 37866 Number of extensions: 832434 Number of successful extensions: 2011 Number of sequences better than 10.0: 17 Number of HSP's better than 10.0 without gapping: 3 Number of HSP's successfully gapped in prelim test: 14 Number of HSP's that attempted gapping in prelim test: 2003 Number of HSP's gapped (non-prelim): 22 length of query: 463 length of database: 18,247,518 effective HSP length: 106 effective length of query: 357 effective length of database: 14,233,722 effective search space: 5081438754 effective search space used: 5081438754 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.