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Search of human proteins with 50301238
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50301238 glutathione reductase [Homo sapiens]
(522 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50301238 glutathione reductase [Homo sapiens] 1045 0.0
gi|22035672 thioredoxin reductase 2 precursor [Homo sapiens] 304 1e-82
gi|33519426 thioredoxin reductase 1 isoform 2 [Homo sapiens] 262 6e-70
gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens] 262 6e-70
gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens] 262 6e-70
gi|33519430 thioredoxin reductase 1 isoform 2 [Homo sapiens] 262 6e-70
gi|33519428 thioredoxin reductase 1 isoform 2 [Homo sapiens] 262 6e-70
gi|91199540 dihydrolipoamide dehydrogenase precursor [Homo sapiens] 180 2e-45
gi|226437568 apoptosis-inducing factor, mitochondrion-associated... 53 8e-07
gi|65787454 apoptosis-inducing factor, mitochondrion-associated,... 53 8e-07
gi|21389617 apoptosis-inducing factor, mitochondrion-associated,... 53 8e-07
gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens] 42 0.002
gi|22202629 programmed cell death 8 isoform 2 [Homo sapiens] 40 0.007
gi|4757732 programmed cell death 8 isoform 1 [Homo sapiens] 40 0.007
gi|229577391 pyridine nucleotide-disulphide oxidoreductase domai... 39 0.015
gi|122939153 nicotinamide nucleotide transhydrogenase [Homo sapi... 34 0.28
gi|122939155 nicotinamide nucleotide transhydrogenase [Homo sapi... 34 0.28
gi|239757043 PREDICTED: functional smad suppressing element 18 [... 34 0.37
gi|239751555 PREDICTED: functional smad suppressing element 18 [... 34 0.37
gi|239746067 PREDICTED: functional smad suppressing element 18 [... 34 0.37
gi|239745938 PREDICTED: hypothetical protein [Homo sapiens] 34 0.37
gi|4758392 forkhead box D1 [Homo sapiens] 33 0.49
gi|40254834 kinesin family member 1C [Homo sapiens] 33 0.49
gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial... 33 0.63
gi|133908614 glycerol-3-phosphate dehydrogenase 2, mitochondrial... 33 0.63
gi|239754611 PREDICTED: hypothetical protein [Homo sapiens] 33 0.83
gi|195927006 programmed cell death 8 isoform 5 [Homo sapiens] 32 1.4
gi|115334682 SNAP25-interacting protein [Homo sapiens] 32 1.4
gi|4557735 monoamine oxidase A [Homo sapiens] 32 1.8
gi|237681069 spatacsin isoform 2 [Homo sapiens] 32 1.8
>gi|50301238 glutathione reductase [Homo sapiens]
Length = 522
Score = 1045 bits (2701), Expect = 0.0
Identities = 522/522 (100%), Positives = 522/522 (100%)
Query: 1 MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAG 60
MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAG
Sbjct: 1 MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAG 60
Query: 61 AVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHS 120
AVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHS
Sbjct: 61 AVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHS 120
Query: 121 EFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDP 180
EFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDP
Sbjct: 121 EFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDP 180
Query: 181 KPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAG 240
KPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAG
Sbjct: 181 KPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAG 240
Query: 241 YIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKK 300
YIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKK
Sbjct: 241 YIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKK 300
Query: 301 TLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVD 360
TLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVD
Sbjct: 301 TLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVD 360
Query: 361 EFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPP 420
EFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPP
Sbjct: 361 EFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPP 420
Query: 421 IGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQ 480
IGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQ
Sbjct: 421 IGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQ 480
Query: 481 GLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR 522
GLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
Sbjct: 481 GLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR 522
>gi|22035672 thioredoxin reductase 2 precursor [Homo sapiens]
Length = 524
Score = 304 bits (779), Expect = 1e-82
Identities = 193/484 (39%), Positives = 277/484 (57%), Gaps = 27/484 (5%)
Query: 58 AAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVESHK---------LGGTCVNVGCV 108
AA YD LV+GGGSGGLA A+ AA+LG + AVV+ + LGGTCVNVGC+
Sbjct: 33 AAAGQRDYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCI 92
Query: 109 PKKVMWNTAVHSEFMHDHADYGFPSCEG-KFNWRVIKEKRDAYVSRLNAIYQNNLTKSHI 167
PKK+M A+ + D +YG+ + +WR + E +V LN ++ L +
Sbjct: 93 PKKLMHQAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKV 152
Query: 168 EIIRGHAAFTSDPKPTIEVSGKK---YTAPHILIATGGMPSTPHESQIPGA-SLGITSDG 223
+ A+F + G K +A HI+IATGG P P + I GA GITSD
Sbjct: 153 KYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYP--THIEGALEYGITSDD 210
Query: 224 FFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELE 283
F L+E PG++++VGA Y+A+E AG L+ +G T++M+R LR FD +S+ E +
Sbjct: 211 IFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMR-SIPLRGFDQQMSSMVIEHMA 269
Query: 284 NAGVEVLKFSQVKEVKKTLSG-LEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDL 342
+ G L+ V++ G L+V+ + G+ T D +LWAIGRVP+T+ L
Sbjct: 270 SHGTRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTF----DTVLWAIGRVPDTRSL 325
Query: 343 SLNKLGIQTD-DKGHIIVDEFQNTNVKGIYAVGDVC-GKALLTPVAIAAGRKLAHRLFEY 400
+L K G+ T D I+VD + T+V IYA+GDV G+ LTP+AI AGR L RLF
Sbjct: 326 NLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGG 385
Query: 401 KEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKR-KT 459
D +DY+N+PT VF+ G VGL+E+EA+ ++G E+V+ Y + P+ V R +
Sbjct: 386 SSD-LMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDAS 444
Query: 460 KCVMKMVCANK-EEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEEL 518
+C +KMVC + + V+G+H G E+ QGFA+ +K GA+ A TV IHPT SEE+
Sbjct: 445 QCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEV 504
Query: 519 VTLR 522
V LR
Sbjct: 505 VKLR 508
>gi|33519426 thioredoxin reductase 1 isoform 2 [Homo sapiens]
Length = 499
Score = 262 bits (669), Expect = 6e-70
Identities = 172/485 (35%), Positives = 262/485 (54%), Gaps = 43/485 (8%)
Query: 65 YDYLVIGGGSGGLASARRAAELGARAAVVE---------SHKLGGTCVNVGCVPKKVMWN 115
YD ++IGGGSGGLA+A+ AA+ G + V++ LGGTCVNVGC+PKK+M
Sbjct: 13 YDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQ 72
Query: 116 TAVHSEFMHDHADYGFPSCEG-KFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHA 174
A+ + + D +YG+ E K +W + E ++ LN Y+ L + + +
Sbjct: 73 AALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYG 132
Query: 175 AFTSDPKPTIEVSGKK-----YTAPHILIATGGMPSTPHESQIPG-ASLGITSDGFFQLE 228
F + I+ + K Y+A LIATG P IPG I+SD F L
Sbjct: 133 QFIGPHR--IKATNNKGKEKIYSAERFLIATG---ERPRYLGIPGDKEYCISSDDLFSLP 187
Query: 229 ELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVE 288
PG++++VGA Y+A+E AG L+ +G ++M+R +LR FD ++ E +E G++
Sbjct: 188 YCPGKTLVVGASYVALECAGFLAGIGLDVTVMVR-SILLRGFDQDMANKIGEHMEEHGIK 246
Query: 289 VLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIP--------DVDCLLWAIGRVPNTK 340
++ +V++ +G PGRL V+ + + ++ AIGR T+
Sbjct: 247 FIRQFVPIKVEQIEAG--------TPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTR 298
Query: 341 DLSLNKLGIQTDDK-GHIIVDEFQNTNVKGIYAVGDVC-GKALLTPVAIAAGRKLAHRLF 398
+ L +G++ ++K G I V + + TNV IYA+GD+ K LTPVAI AGR LA RL+
Sbjct: 299 KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY 358
Query: 399 EYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKR- 457
K DY N+PT VF+ G GL+E++A+ K+G EN++ Y + F P+ + R
Sbjct: 359 A-GSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRD 417
Query: 458 KTKCVMKMVCANKE-EKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSE 516
KC K++C K+ E+VVG H+ G E+ QGFA A+K G TK D+T+ IHP +E
Sbjct: 418 NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE 477
Query: 517 ELVTL 521
TL
Sbjct: 478 VFTTL 482
>gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens]
Length = 649
Score = 262 bits (669), Expect = 6e-70
Identities = 172/485 (35%), Positives = 262/485 (54%), Gaps = 43/485 (8%)
Query: 65 YDYLVIGGGSGGLASARRAAELGARAAVVE---------SHKLGGTCVNVGCVPKKVMWN 115
YD ++IGGGSGGLA+A+ AA+ G + V++ LGGTCVNVGC+PKK+M
Sbjct: 163 YDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQ 222
Query: 116 TAVHSEFMHDHADYGFPSCEG-KFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHA 174
A+ + + D +YG+ E K +W + E ++ LN Y+ L + + +
Sbjct: 223 AALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYG 282
Query: 175 AFTSDPKPTIEVSGKK-----YTAPHILIATGGMPSTPHESQIPG-ASLGITSDGFFQLE 228
F + I+ + K Y+A LIATG P IPG I+SD F L
Sbjct: 283 QFIGPHR--IKATNNKGKEKIYSAERFLIATG---ERPRYLGIPGDKEYCISSDDLFSLP 337
Query: 229 ELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVE 288
PG++++VGA Y+A+E AG L+ +G ++M+R +LR FD ++ E +E G++
Sbjct: 338 YCPGKTLVVGASYVALECAGFLAGIGLDVTVMVR-SILLRGFDQDMANKIGEHMEEHGIK 396
Query: 289 VLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIP--------DVDCLLWAIGRVPNTK 340
++ +V++ +G PGRL V+ + + ++ AIGR T+
Sbjct: 397 FIRQFVPIKVEQIEAG--------TPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTR 448
Query: 341 DLSLNKLGIQTDDK-GHIIVDEFQNTNVKGIYAVGDVC-GKALLTPVAIAAGRKLAHRLF 398
+ L +G++ ++K G I V + + TNV IYA+GD+ K LTPVAI AGR LA RL+
Sbjct: 449 KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY 508
Query: 399 EYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKR- 457
K DY N+PT VF+ G GL+E++A+ K+G EN++ Y + F P+ + R
Sbjct: 509 A-GSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRD 567
Query: 458 KTKCVMKMVCANKE-EKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSE 516
KC K++C K+ E+VVG H+ G E+ QGFA A+K G TK D+T+ IHP +E
Sbjct: 568 NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE 627
Query: 517 ELVTL 521
TL
Sbjct: 628 VFTTL 632
>gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens]
Length = 551
Score = 262 bits (669), Expect = 6e-70
Identities = 172/485 (35%), Positives = 262/485 (54%), Gaps = 43/485 (8%)
Query: 65 YDYLVIGGGSGGLASARRAAELGARAAVVE---------SHKLGGTCVNVGCVPKKVMWN 115
YD ++IGGGSGGLA+A+ AA+ G + V++ LGGTCVNVGC+PKK+M
Sbjct: 65 YDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQ 124
Query: 116 TAVHSEFMHDHADYGFPSCEG-KFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHA 174
A+ + + D +YG+ E K +W + E ++ LN Y+ L + + +
Sbjct: 125 AALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYG 184
Query: 175 AFTSDPKPTIEVSGKK-----YTAPHILIATGGMPSTPHESQIPG-ASLGITSDGFFQLE 228
F + I+ + K Y+A LIATG P IPG I+SD F L
Sbjct: 185 QFIGPHR--IKATNNKGKEKIYSAERFLIATG---ERPRYLGIPGDKEYCISSDDLFSLP 239
Query: 229 ELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVE 288
PG++++VGA Y+A+E AG L+ +G ++M+R +LR FD ++ E +E G++
Sbjct: 240 YCPGKTLVVGASYVALECAGFLAGIGLDVTVMVR-SILLRGFDQDMANKIGEHMEEHGIK 298
Query: 289 VLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIP--------DVDCLLWAIGRVPNTK 340
++ +V++ +G PGRL V+ + + ++ AIGR T+
Sbjct: 299 FIRQFVPIKVEQIEAG--------TPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTR 350
Query: 341 DLSLNKLGIQTDDK-GHIIVDEFQNTNVKGIYAVGDVC-GKALLTPVAIAAGRKLAHRLF 398
+ L +G++ ++K G I V + + TNV IYA+GD+ K LTPVAI AGR LA RL+
Sbjct: 351 KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY 410
Query: 399 EYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKR- 457
K DY N+PT VF+ G GL+E++A+ K+G EN++ Y + F P+ + R
Sbjct: 411 A-GSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRD 469
Query: 458 KTKCVMKMVCANKE-EKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSE 516
KC K++C K+ E+VVG H+ G E+ QGFA A+K G TK D+T+ IHP +E
Sbjct: 470 NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE 529
Query: 517 ELVTL 521
TL
Sbjct: 530 VFTTL 534
>gi|33519430 thioredoxin reductase 1 isoform 2 [Homo sapiens]
Length = 499
Score = 262 bits (669), Expect = 6e-70
Identities = 172/485 (35%), Positives = 262/485 (54%), Gaps = 43/485 (8%)
Query: 65 YDYLVIGGGSGGLASARRAAELGARAAVVE---------SHKLGGTCVNVGCVPKKVMWN 115
YD ++IGGGSGGLA+A+ AA+ G + V++ LGGTCVNVGC+PKK+M
Sbjct: 13 YDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQ 72
Query: 116 TAVHSEFMHDHADYGFPSCEG-KFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHA 174
A+ + + D +YG+ E K +W + E ++ LN Y+ L + + +
Sbjct: 73 AALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYG 132
Query: 175 AFTSDPKPTIEVSGKK-----YTAPHILIATGGMPSTPHESQIPG-ASLGITSDGFFQLE 228
F + I+ + K Y+A LIATG P IPG I+SD F L
Sbjct: 133 QFIGPHR--IKATNNKGKEKIYSAERFLIATG---ERPRYLGIPGDKEYCISSDDLFSLP 187
Query: 229 ELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVE 288
PG++++VGA Y+A+E AG L+ +G ++M+R +LR FD ++ E +E G++
Sbjct: 188 YCPGKTLVVGASYVALECAGFLAGIGLDVTVMVR-SILLRGFDQDMANKIGEHMEEHGIK 246
Query: 289 VLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIP--------DVDCLLWAIGRVPNTK 340
++ +V++ +G PGRL V+ + + ++ AIGR T+
Sbjct: 247 FIRQFVPIKVEQIEAG--------TPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTR 298
Query: 341 DLSLNKLGIQTDDK-GHIIVDEFQNTNVKGIYAVGDVC-GKALLTPVAIAAGRKLAHRLF 398
+ L +G++ ++K G I V + + TNV IYA+GD+ K LTPVAI AGR LA RL+
Sbjct: 299 KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY 358
Query: 399 EYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKR- 457
K DY N+PT VF+ G GL+E++A+ K+G EN++ Y + F P+ + R
Sbjct: 359 A-GSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRD 417
Query: 458 KTKCVMKMVCANKE-EKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSE 516
KC K++C K+ E+VVG H+ G E+ QGFA A+K G TK D+T+ IHP +E
Sbjct: 418 NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE 477
Query: 517 ELVTL 521
TL
Sbjct: 478 VFTTL 482
>gi|33519428 thioredoxin reductase 1 isoform 2 [Homo sapiens]
Length = 499
Score = 262 bits (669), Expect = 6e-70
Identities = 172/485 (35%), Positives = 262/485 (54%), Gaps = 43/485 (8%)
Query: 65 YDYLVIGGGSGGLASARRAAELGARAAVVE---------SHKLGGTCVNVGCVPKKVMWN 115
YD ++IGGGSGGLA+A+ AA+ G + V++ LGGTCVNVGC+PKK+M
Sbjct: 13 YDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQ 72
Query: 116 TAVHSEFMHDHADYGFPSCEG-KFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHA 174
A+ + + D +YG+ E K +W + E ++ LN Y+ L + + +
Sbjct: 73 AALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYG 132
Query: 175 AFTSDPKPTIEVSGKK-----YTAPHILIATGGMPSTPHESQIPG-ASLGITSDGFFQLE 228
F + I+ + K Y+A LIATG P IPG I+SD F L
Sbjct: 133 QFIGPHR--IKATNNKGKEKIYSAERFLIATG---ERPRYLGIPGDKEYCISSDDLFSLP 187
Query: 229 ELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVE 288
PG++++VGA Y+A+E AG L+ +G ++M+R +LR FD ++ E +E G++
Sbjct: 188 YCPGKTLVVGASYVALECAGFLAGIGLDVTVMVR-SILLRGFDQDMANKIGEHMEEHGIK 246
Query: 289 VLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIP--------DVDCLLWAIGRVPNTK 340
++ +V++ +G PGRL V+ + + ++ AIGR T+
Sbjct: 247 FIRQFVPIKVEQIEAG--------TPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTR 298
Query: 341 DLSLNKLGIQTDDK-GHIIVDEFQNTNVKGIYAVGDVC-GKALLTPVAIAAGRKLAHRLF 398
+ L +G++ ++K G I V + + TNV IYA+GD+ K LTPVAI AGR LA RL+
Sbjct: 299 KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY 358
Query: 399 EYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKR- 457
K DY N+PT VF+ G GL+E++A+ K+G EN++ Y + F P+ + R
Sbjct: 359 A-GSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRD 417
Query: 458 KTKCVMKMVCANKE-EKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSE 516
KC K++C K+ E+VVG H+ G E+ QGFA A+K G TK D+T+ IHP +E
Sbjct: 418 NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE 477
Query: 517 ELVTL 521
TL
Sbjct: 478 VFTTL 482
>gi|91199540 dihydrolipoamide dehydrogenase precursor [Homo sapiens]
Length = 509
Score = 180 bits (457), Expect = 2e-45
Identities = 143/477 (29%), Positives = 227/477 (47%), Gaps = 53/477 (11%)
Query: 66 DYLVIGGGSGGLASARRAAELGARAAVVESHK-LGGTCVNVGCVPKKVMWNTAVHSEFMH 124
D VIG G GG +A +AA+LG + +E ++ LGGTC+NVGC+P K + N + + H
Sbjct: 43 DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAH 102
Query: 125 --DHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKP 182
D A G E + N + E++ V L + ++ + + G+ T +
Sbjct: 103 GKDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGKNQV 162
Query: 183 TIEVSG---KKYTAPHILIATGGMPSTPHESQIPGASLG----ITSDGFFQLEELPGRSV 235
T + + +ILIATG + PG ++ ++S G L+++P + V
Sbjct: 163 TATKADGGTQVIDTKNILIATGS-----EVTPFPGITIDEDTIVSSTGALSLKKVPEKMV 217
Query: 236 IVGAGYIAVEMAGILSALGSKTSLM--IRHDKVLRSFDSMISTNCTEELENAGVEVLKFS 293
++GAG I VE+ + LG+ + + + H + D IS N L+ G + +
Sbjct: 218 VIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGV-GIDMEISKNFQRILQKQGFKFKLNT 276
Query: 294 QVKEVKKTLSG-LEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTD 352
+V K G ++VS+ A G+ V+T D LL IGR P TK+L L +LGI+ D
Sbjct: 277 KVTGATKKSDGKIDVSIEAASGGKAEVITC----DVLLVCIGRRPFTKNLGLEELGIELD 332
Query: 353 DKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDS-------- 404
+G I V+ T + IYA+GDV AG LAH+ ED
Sbjct: 333 PRGRIPVNTRFQTKIPNIYAIGDV-----------VAGPMLAHK----AEDEGIICVEGM 377
Query: 405 -----KLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKT 459
+DYN +P+V+++HP + VG +E E + + GIE K F A T T
Sbjct: 378 AGGAVHIDYNCVPSVIYTHPEVAWVGKSE-EQLKEEGIE-YKVGKFPFAANSRAKTNADT 435
Query: 460 KCVMKMVCANKEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSE 516
++K++ ++V+G H+ G G EM+ A+A++ GA+ D HPT SE
Sbjct: 436 DGMVKILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSE 492
>gi|226437568 apoptosis-inducing factor, mitochondrion-associated, 3
isoform 3 [Homo sapiens]
Length = 604
Score = 52.8 bits (125), Expect = 8e-07
Identities = 80/347 (23%), Positives = 136/347 (39%), Gaps = 62/347 (17%)
Query: 57 PAAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNT 116
P+AG +S + L++G G+ GL A + G +V C
Sbjct: 193 PSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIV-------LCT------------- 232
Query: 117 AVHSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAF 176
+ H Y P + + D +L + IE++
Sbjct: 233 ------LDRHLPYDRPK---------LSKSLDTQPEQLALRPKEFFRAYGIEVLTEAQVV 277
Query: 177 TSD--PKPTIEVSGKKYTAPHILIATGGMPSTPH--ESQIPGASLGITSDGFFQLEELP- 231
T D K + G K +L+A G P T ++ T + ++ L
Sbjct: 278 TVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLAR 337
Query: 232 GRSVIV-GAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVL 290
GR+V+V GAG++ +E+A L+ S++ + R F E + A +++
Sbjct: 338 GRNVVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRF-------LGERVGRALMKMF 390
Query: 291 KFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTM----IPDVDCLLWAIGRVPNTKDLSLNK 346
+ ++VK +T EVS + G+L + + + D + IG VP T L +
Sbjct: 391 ENNRVKFYMQT----EVSELRGQEGKLKEVVLKSSKVVRADVCVVGIGAVPATG--FLRQ 444
Query: 347 LGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKL 393
GI D +G I V++ TNV G++A GD A+ P+A RK+
Sbjct: 445 SGIGLDSRGFIPVNKMMQTNVPGVFAAGD----AVTFPLAWRNNRKV 487
>gi|65787454 apoptosis-inducing factor, mitochondrion-associated, 3
isoform 2 [Homo sapiens]
Length = 598
Score = 52.8 bits (125), Expect = 8e-07
Identities = 80/347 (23%), Positives = 136/347 (39%), Gaps = 62/347 (17%)
Query: 57 PAAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNT 116
P+AG +S + L++G G+ GL A + G +V C
Sbjct: 187 PSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIV-------LCT------------- 226
Query: 117 AVHSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAF 176
+ H Y P + + D +L + IE++
Sbjct: 227 ------LDRHLPYDRPK---------LSKSLDTQPEQLALRPKEFFRAYGIEVLTEAQVV 271
Query: 177 TSD--PKPTIEVSGKKYTAPHILIATGGMPSTPH--ESQIPGASLGITSDGFFQLEELP- 231
T D K + G K +L+A G P T ++ T + ++ L
Sbjct: 272 TVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLAR 331
Query: 232 GRSVIV-GAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVL 290
GR+V+V GAG++ +E+A L+ S++ + R F E + A +++
Sbjct: 332 GRNVVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRF-------LGERVGRALMKMF 384
Query: 291 KFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTM----IPDVDCLLWAIGRVPNTKDLSLNK 346
+ ++VK +T EVS + G+L + + + D + IG VP T L +
Sbjct: 385 ENNRVKFYMQT----EVSELRGQEGKLKEVVLKSSKVVRADVCVVGIGAVPATG--FLRQ 438
Query: 347 LGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKL 393
GI D +G I V++ TNV G++A GD A+ P+A RK+
Sbjct: 439 SGIGLDSRGFIPVNKMMQTNVPGVFAAGD----AVTFPLAWRNNRKV 481
>gi|21389617 apoptosis-inducing factor, mitochondrion-associated, 3
isoform 1 [Homo sapiens]
Length = 605
Score = 52.8 bits (125), Expect = 8e-07
Identities = 80/347 (23%), Positives = 136/347 (39%), Gaps = 62/347 (17%)
Query: 57 PAAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNT 116
P+AG +S + L++G G+ GL A + G +V C
Sbjct: 187 PSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIV-------LCT------------- 226
Query: 117 AVHSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAF 176
+ H Y P + + D +L + IE++
Sbjct: 227 ------LDRHLPYDRPK---------LSKSLDTQPEQLALRPKEFFRAYGIEVLTEAQVV 271
Query: 177 TSD--PKPTIEVSGKKYTAPHILIATGGMPSTPH--ESQIPGASLGITSDGFFQLEELP- 231
T D K + G K +L+A G P T ++ T + ++ L
Sbjct: 272 TVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLAR 331
Query: 232 GRSVIV-GAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVL 290
GR+V+V GAG++ +E+A L+ S++ + R F E + A +++
Sbjct: 332 GRNVVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRF-------LGERVGRALMKMF 384
Query: 291 KFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTM----IPDVDCLLWAIGRVPNTKDLSLNK 346
+ ++VK +T EVS + G+L + + + D + IG VP T L +
Sbjct: 385 ENNRVKFYMQT----EVSELRGQEGKLKEVVLKSSKVVRADVCVVGIGAVPATG--FLRQ 438
Query: 347 LGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKL 393
GI D +G I V++ TNV G++A GD A+ P+A RK+
Sbjct: 439 SGIGLDSRGFIPVNKMMQTNVPGVFAAGD----AVTFPLAWRNNRKV 481
>gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens]
Length = 610
Score = 41.6 bits (96), Expect = 0.002
Identities = 35/128 (27%), Positives = 53/128 (41%), Gaps = 19/128 (14%)
Query: 29 LLPEPAALTRALSRAMACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASARRAAELGA 88
L+ + A + L +A + Q P+ D +VIG G GGLA+A A+ G
Sbjct: 44 LVTDKEARKKVLKQAFSANQVPE------------KLDVVVIGSGFGGLAAAAILAKAGK 91
Query: 89 RAAVVESH-KLGGTCVNVGCVPKKVMWNTAVHSEFMHDHADYG----FPSCEGKFNWRVI 143
R V+E H K GG C G + ++T +H + G EG+ +W +
Sbjct: 92 RVLVLEQHTKAGGCCHTFG--KNGLEFDTGIHYIGRMEEGSIGRFILDQITEGQLDWAPL 149
Query: 144 KEKRDAYV 151
D V
Sbjct: 150 SSPFDIMV 157
>gi|22202629 programmed cell death 8 isoform 2 [Homo sapiens]
Length = 609
Score = 39.7 bits (91), Expect = 0.007
Identities = 87/371 (23%), Positives = 137/371 (36%), Gaps = 60/371 (16%)
Query: 29 LLPEPAALTRALSRAMACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASAR--RAAEL 86
L PE ALS A E PQ P+ +L+IGGG+ A+AR RA +
Sbjct: 100 LTPEQKQKKAALS---ASEGEEVPQDKAPS-----HVPFLLIGGGTAAFAAARSIRARDP 151
Query: 87 GARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEGKFNWRVIKEK 146
GAR +V P+ + E P+ ++ K
Sbjct: 152 GARVLIVSED------------PELPYMRPPLSKELWFSDD----PNVTKTLRFKQWNGK 195
Query: 147 RDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEV--------SGKKYTAPHILI 198
+ + + Y + HIE G A T ++V G + T LI
Sbjct: 196 ERSIYFQPPSFYVSAQDLPHIEN-GGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLI 254
Query: 199 ATGGMPSTPHESQIPGASLGITSD-----GFFQLEELPGRSV----IVGAGYIAVEMAGI 249
ATGG P + GA + + G F+ E R V I+G G++ E+A
Sbjct: 255 ATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACA 314
Query: 250 LS----ALGSKT-SLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSG 304
L ALG++ L + + +S E++ GV+V+ + V+ V +
Sbjct: 315 LGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGK 374
Query: 305 LEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQN 364
L ++ GR + D ++ A+G PN + L I +D G + E Q
Sbjct: 375 L---LIKLKDGRK------VETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQA 425
Query: 365 TNVKGIYAVGD 375
+ I+ GD
Sbjct: 426 RS--NIWVAGD 434
>gi|4757732 programmed cell death 8 isoform 1 [Homo sapiens]
Length = 613
Score = 39.7 bits (91), Expect = 0.007
Identities = 87/371 (23%), Positives = 137/371 (36%), Gaps = 60/371 (16%)
Query: 29 LLPEPAALTRALSRAMACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASAR--RAAEL 86
L PE ALS A E PQ P+ +L+IGGG+ A+AR RA +
Sbjct: 104 LTPEQKQKKAALS---ASEGEEVPQDKAPS-----HVPFLLIGGGTAAFAAARSIRARDP 155
Query: 87 GARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEGKFNWRVIKEK 146
GAR +V P+ + E P+ ++ K
Sbjct: 156 GARVLIVSED------------PELPYMRPPLSKELWFSDD----PNVTKTLRFKQWNGK 199
Query: 147 RDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEV--------SGKKYTAPHILI 198
+ + + Y + HIE G A T ++V G + T LI
Sbjct: 200 ERSIYFQPPSFYVSAQDLPHIEN-GGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLI 258
Query: 199 ATGGMPSTPHESQIPGASLGITSD-----GFFQLEELPGRSV----IVGAGYIAVEMAGI 249
ATGG P + GA + + G F+ E R V I+G G++ E+A
Sbjct: 259 ATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACA 318
Query: 250 LS----ALGSKT-SLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSG 304
L ALG++ L + + +S E++ GV+V+ + V+ V +
Sbjct: 319 LGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGK 378
Query: 305 LEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQN 364
L ++ GR + D ++ A+G PN + L I +D G + E Q
Sbjct: 379 L---LIKLKDGRK------VETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQA 429
Query: 365 TNVKGIYAVGD 375
+ I+ GD
Sbjct: 430 RS--NIWVAGD 438
>gi|229577391 pyridine nucleotide-disulphide oxidoreductase domain 2
[Homo sapiens]
Length = 581
Score = 38.5 bits (88), Expect = 0.015
Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 3/79 (3%)
Query: 34 AALTRALSRAMACRQEP--QPQGPPPAAGAVASYDYLVIGGGSGGLASARRAAELGARAA 91
AA R L +A+A P + G YD +VIG G GL +A LG A
Sbjct: 2 AASGRGLCKAVAASPFPAWRRDNTEARGGLKPEYDAVVIGAGHNGLVAAAYLQRLGVNTA 61
Query: 92 VVE-SHKLGGTCVNVGCVP 109
V E H +GG V +P
Sbjct: 62 VFERRHVIGGAAVTEEIIP 80
>gi|122939153 nicotinamide nucleotide transhydrogenase [Homo
sapiens]
Length = 1086
Score = 34.3 bits (77), Expect = 0.28
Identities = 22/51 (43%), Positives = 26/51 (50%), Gaps = 7/51 (13%)
Query: 54 GPPPAAGAVASYDYLVIGGGSGGLASARRAAELGA-------RAAVVESHK 97
G AAG V L++GGG GLASA A +GA RAA +E K
Sbjct: 217 GQITAAGKVPPAKILIVGGGVAGLASAGAAKSMGAIVRGFDTRAAALEQFK 267
>gi|122939155 nicotinamide nucleotide transhydrogenase [Homo
sapiens]
Length = 1086
Score = 34.3 bits (77), Expect = 0.28
Identities = 22/51 (43%), Positives = 26/51 (50%), Gaps = 7/51 (13%)
Query: 54 GPPPAAGAVASYDYLVIGGGSGGLASARRAAELGA-------RAAVVESHK 97
G AAG V L++GGG GLASA A +GA RAA +E K
Sbjct: 217 GQITAAGKVPPAKILIVGGGVAGLASAGAAKSMGAIVRGFDTRAAALEQFK 267
>gi|239757043 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 996
Score = 33.9 bits (76), Expect = 0.37
Identities = 38/109 (34%), Positives = 40/109 (36%), Gaps = 18/109 (16%)
Query: 5 PRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQP------QGPPPA 58
P AL G S +AF L L EP + A Q PQ GPPP
Sbjct: 492 PSALGCALGESPALLRQAF----LDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPP 547
Query: 59 AGAVASYDYLVIG--GGSGGLAS------ARRAAELGARAAVVESHKLG 99
AG S D L GGSGG S A A GA AA S G
Sbjct: 548 AGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAG 596
>gi|239751555 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 33.9 bits (76), Expect = 0.37
Identities = 38/109 (34%), Positives = 40/109 (36%), Gaps = 18/109 (16%)
Query: 5 PRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQP------QGPPPA 58
P AL G S +AF L L EP + A Q PQ GPPP
Sbjct: 492 PSALGCALGESPALLRQAF----LDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPP 547
Query: 59 AGAVASYDYLVIG--GGSGGLAS------ARRAAELGARAAVVESHKLG 99
AG S D L GGSGG S A A GA AA S G
Sbjct: 548 AGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAG 596
>gi|239746067 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 33.9 bits (76), Expect = 0.37
Identities = 38/109 (34%), Positives = 40/109 (36%), Gaps = 18/109 (16%)
Query: 5 PRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQP------QGPPPA 58
P AL G S +AF L L EP + A Q PQ GPPP
Sbjct: 492 PSALGCALGESPALLRQAF----LDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPP 547
Query: 59 AGAVASYDYLVIG--GGSGGLAS------ARRAAELGARAAVVESHKLG 99
AG S D L GGSGG S A A GA AA S G
Sbjct: 548 AGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAG 596
>gi|239745938 PREDICTED: hypothetical protein [Homo sapiens]
Length = 336
Score = 33.9 bits (76), Expect = 0.37
Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 26/102 (25%)
Query: 10 AGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMA-CRQEPQPQGPPPAAGAVASYDYL 68
A A P W +A A+R LP+P R + CR+ P GP
Sbjct: 179 ATAAPPWASSATAWR-----LPQPRRRRRPTCPCCSRCRELSPPMGPD------------ 221
Query: 69 VIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPK 110
+GGG GG A A A GA+ + E+ C +GC+P+
Sbjct: 222 -LGGGGGG-AGAGAGAGAGAQRSAAEA----AGC--LGCLPR 255
>gi|4758392 forkhead box D1 [Homo sapiens]
Length = 465
Score = 33.5 bits (75), Expect = 0.49
Identities = 20/45 (44%), Positives = 24/45 (53%), Gaps = 6/45 (13%)
Query: 50 PQPQGPPPAAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVE 94
P P GP PAAGA A GGG GG A +A GA+ +V+
Sbjct: 87 PAPPGPAPAAGAGAG------GGGGGGGAGGGGSAGSGAKNPLVK 125
>gi|40254834 kinesin family member 1C [Homo sapiens]
Length = 1103
Score = 33.5 bits (75), Expect = 0.49
Identities = 22/56 (39%), Positives = 27/56 (48%)
Query: 39 ALSRAMACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVE 94
AL CR +P GP A AVA + +G GG A + +E GAR A VE
Sbjct: 776 ALKMRELCRTYGKPDGPGDAWRAVARDVWDTVGEEEGGGAGSGGGSEEGARGAEVE 831
>gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial
[Homo sapiens]
Length = 727
Score = 33.1 bits (74), Expect = 0.63
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 6/62 (9%)
Query: 39 ALSRAMACRQEPQPQGPPPAAGAV------ASYDYLVIGGGSGGLASARRAAELGARAAV 92
A +A C EP + PP + + +D LVIGGG+ G A A G + A+
Sbjct: 38 AYVKAADCISEPVNREPPSREAQLLTLQNTSEFDILVIGGGATGSGCALDAVTRGLKTAL 97
Query: 93 VE 94
VE
Sbjct: 98 VE 99
>gi|133908614 glycerol-3-phosphate dehydrogenase 2, mitochondrial
[Homo sapiens]
Length = 727
Score = 33.1 bits (74), Expect = 0.63
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 6/62 (9%)
Query: 39 ALSRAMACRQEPQPQGPPPAAGAV------ASYDYLVIGGGSGGLASARRAAELGARAAV 92
A +A C EP + PP + + +D LVIGGG+ G A A G + A+
Sbjct: 38 AYVKAADCISEPVNREPPSREAQLLTLQNTSEFDILVIGGGATGSGCALDAVTRGLKTAL 97
Query: 93 VE 94
VE
Sbjct: 98 VE 99
>gi|239754611 PREDICTED: hypothetical protein [Homo sapiens]
Length = 178
Score = 32.7 bits (73), Expect = 0.83
Identities = 24/83 (28%), Positives = 33/83 (39%), Gaps = 7/83 (8%)
Query: 5 PRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAGAVAS 64
P G GP+ RR +R R ++ P R ACR P+P P GA
Sbjct: 51 PELERGGPGPTDRRTSRRLRAAIVAAASPGLH----GRPAACRGHPRPTPARPPTGAP-- 104
Query: 65 YDYLVIGGGSGGLASARRAAELG 87
+ + G + L A+R A G
Sbjct: 105 -EAPALSGRAARLHGAQRGAPAG 126
>gi|195927006 programmed cell death 8 isoform 5 [Homo sapiens]
Length = 324
Score = 32.0 bits (71), Expect = 1.4
Identities = 64/249 (25%), Positives = 91/249 (36%), Gaps = 51/249 (20%)
Query: 29 LLPEPAALTRALSRAMACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASAR--RAAEL 86
L PE ALS A E PQ P+ +L+IGGG+ A+AR RA +
Sbjct: 104 LTPEQKQKKAALS---ASEGEEVPQDKAPS-----HVPFLLIGGGTAAFAAARSIRARDP 155
Query: 87 GARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHSE--FMHDHADYGFPSCEGKFNWRVIK 144
GAR +V P+ + E F D P+ ++
Sbjct: 156 GARVLIVSED------------PELPYMRPPLSKELWFSDD------PNVTKTLRFKQWN 197
Query: 145 EKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEV--------SGKKYTAPHI 196
K + + + Y + HIE G A T ++V G + T
Sbjct: 198 GKERSIYFQPPSFYVSAQDLPHIE-NGGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKC 256
Query: 197 LIATGGMPSTPHESQIPGASLGITSD-----GFFQLEELPGRSV----IVGAGYIAVEMA 247
LIATGG P + GA + + G F+ E R V I+G G++ E+A
Sbjct: 257 LIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELA 316
Query: 248 GILSALGSK 256
ALG K
Sbjct: 317 ---CALGRK 322
>gi|115334682 SNAP25-interacting protein [Homo sapiens]
Length = 1183
Score = 32.0 bits (71), Expect = 1.4
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Query: 48 QEPQPQGPPPAAGAVASY--DYLVIGGGSGGLASARRAAELG 87
Q+P+ PP + A Y +Y +GGG GG + RR + +G
Sbjct: 7 QDPERSSPPMLSADDAEYPREYRTLGGGGGGGSGGRRFSNVG 48
>gi|4557735 monoamine oxidase A [Homo sapiens]
Length = 527
Score = 31.6 bits (70), Expect = 1.8
Identities = 15/37 (40%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Query: 65 YDYLVIGGGSGGLASARRAAELGARAAVVESH-KLGG 100
+D +VIGGG GL++A+ E G V+E+ ++GG
Sbjct: 14 FDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGG 50
>gi|237681069 spatacsin isoform 2 [Homo sapiens]
Length = 2330
Score = 31.6 bits (70), Expect = 1.8
Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
Query: 7 ALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAGAVASYD 66
A +A AG SW AA +LL+P PA L R +P+ G AAG++
Sbjct: 8 ASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLS 67
Query: 67 YLVIGGGSGG 76
L G GG
Sbjct: 68 -LTPGSRGGG 76
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,121,880
Number of Sequences: 37866
Number of extensions: 940694
Number of successful extensions: 3484
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 3389
Number of HSP's gapped (non-prelim): 79
length of query: 522
length of database: 18,247,518
effective HSP length: 107
effective length of query: 415
effective length of database: 14,195,856
effective search space: 5891280240
effective search space used: 5891280240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.