Guide to the Human Genome
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Name: RUNX1 Sequence: fasta or formatted (453aa) NCBI GI: 49574546
Description:

runt-related transcription factor 1 isoform AML1b

Referenced in:

Ets Family
Additional Genes in Development
Hematopoiesis and Erythrocytes
Zinc Finger Proteins

Other entries for this name:
alt prot [250aa] runt-related transcription factor 1 isoform AML1a
alt prot [480aa] runt-related transcription factor 1 isoform AML1c
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.5         43           2
 C cysteine            0.7          3           1
 D aspartate           4.0         18           2
 E glutamate           3.3         15           2
 F phenylalanine       3.1         14           1
 G glycine             6.8         31           2
 H histidine           2.6         12           2
 I isoleucine          2.6         12           1
 K lysine              2.0          9           1
 L leucine             7.5         34           2
 M methionine          2.9         13           1
 N asparagine          3.5         16           1
 P proline            11.7         53           3
 Q glutamine           4.2         19           1
 R arginine            7.1         32           2
 S serine             12.4         56           2
 T threonine           7.3         33           2
 V valine              4.9         22           2
 W tryptophan          0.7          3           1
 Y tyrosine            3.3         15           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   runt-related transcription factor 1 isoform AML1b [H... 
RUNX1                 0.990   runt-related transcription factor 1 isoform AML1c [H...
RUNX2                 0.617   runt-related transcription factor 2 isoform b [Homo...
RUNX2                 0.615   runt-related transcription factor 2 isoform c 
RUNX2                 0.603   runt-related transcription factor 2 isoform a [Homo...
RUNX1                 0.517   runt-related transcription factor 1 isoform AML1a [...
RUNX3                 0.515   runt-related transcription factor 3 isoform 2 
RUNX3                 0.504   runt-related transcription factor 3 isoform 1 
ARID1A                0.028   AT rich interactive domain 1A isoform a 
ARID1A                0.028   AT rich interactive domain 1A isoform b 
MED14                 0.023   mediator complex subunit 14 
TAF6                  0.019   TBP-associated factor 6 isoform delta 
TAF6                  0.019   TBP-associated factor 6 isoform alpha 
TAF6                  0.019   TBP-associated factor 6 isoform alpha 
TNK2                  0.018   tyrosine kinase, non-receptor, 2 isoform 1 
TNK2                  0.018   tyrosine kinase, non-receptor, 2 isoform 2 
ATN1                  0.018   atrophin-1 
ATN1                  0.018   atrophin-1 
POLR2A                0.017   DNA-directed RNA polymerase II A 
ARID2                 0.016   AT rich interactive domain 2 (ARID, RFX-like) 
NPAS2                 0.016   neuronal PAS domain protein 2 
SFPQ                  0.016   splicing factor proline/glutamine rich (polypyrimidin...
MUC2                  0.015   mucin 2 precursor 
RBM14                 0.015   RNA binding motif protein 14 
TAF6                  0.013   TBP-associated factor 6 isoform gamma 
CRTC2                 0.013   CREB regulated transcription coactivator 2 
TACC2                 0.013   transforming, acidic coiled-coil containing protein ...
ZNF703                0.013   zinc finger protein 703 
MARK3                 0.013   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.013   MAP/microtubule affinity-regulating kinase 3 isoform...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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