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Search of human proteins with 49355818
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|49355818 plexin A1 [Homo sapiens]
(1873 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|49355818 plexin A1 [Homo sapiens] 3796 0.0
gi|59710104 plexin A3 [Homo sapiens] 2550 0.0
gi|113722116 plexin A2 [Homo sapiens] 2452 0.0
gi|157738645 plexin A4 isoform 1 [Homo sapiens] 2442 0.0
gi|253795481 plexin B3 isoform 2 [Homo sapiens] 955 0.0
gi|29336063 plexin B3 isoform 1 [Homo sapiens] 955 0.0
gi|149363636 plexin B2 [Homo sapiens] 932 0.0
gi|157694524 plexin D1 [Homo sapiens] 861 0.0
gi|194272180 plexin B1 [Homo sapiens] 813 0.0
gi|40254442 plexin B1 [Homo sapiens] 813 0.0
gi|157738647 plexin A4 isoform 3 [Homo sapiens] 471 e-132
gi|157738643 plexin A4 isoform 2 [Homo sapiens] 471 e-132
gi|5032223 plexin C1 [Homo sapiens] 421 e-117
gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens] 150 1e-35
gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens] 150 1e-35
gi|153946393 macrophage stimulating 1 receptor precursor [Homo s... 116 2e-25
gi|21361914 semaphorin B [Homo sapiens] 72 7e-12
gi|39777610 semaphorin 4B precursor [Homo sapiens] 68 7e-11
gi|39777608 semaphorin 4B precursor [Homo sapiens] 68 7e-11
gi|126116589 fibrocystin L [Homo sapiens] 68 7e-11
gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens] 58 1e-07
gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens] 58 1e-07
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens] 58 1e-07
gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens] 58 1e-07
gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens] 58 1e-07
gi|157388902 semaphorin 4C [Homo sapiens] 57 1e-07
gi|147904700 semaphorin 5A [Homo sapiens] 55 8e-07
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 52 4e-06
gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens] 52 7e-06
gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens] 51 9e-06
>gi|49355818 plexin A1 [Homo sapiens]
Length = 1873
Score = 3796 bits (9845), Expect = 0.0
Identities = 1873/1873 (100%), Positives = 1873/1873 (100%)
Query: 1 MWAEAGLPRAGGGSQPPFRTFSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRA 60
MWAEAGLPRAGGGSQPPFRTFSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRA
Sbjct: 1 MWAEAGLPRAGGGSQPPFRTFSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRA 60
Query: 61 HVTGPVEDNEKCYPPPSVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFLRL 120
HVTGPVEDNEKCYPPPSVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFLRL
Sbjct: 61 HVTGPVEDNEKCYPPPSVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFLRL 120
Query: 121 DDLFKLGEPHHRKEHYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSS 180
DDLFKLGEPHHRKEHYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSS
Sbjct: 121 DDLFKLGEPHHRKEHYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSS 180
Query: 181 RRLMANEEDADMFGFVYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQL 240
RRLMANEEDADMFGFVYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQL
Sbjct: 181 RRLMANEEDADMFGFVYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQL 240
Query: 241 DTQLTSPDAAGEHFFTSKIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRA 300
DTQLTSPDAAGEHFFTSKIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRA
Sbjct: 241 DTQLTSPDAAGEHFFTSKIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRA 300
Query: 301 LAHQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSCYRGEGKL 360
LAHQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSCYRGEGKL
Sbjct: 301 LAHQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSCYRGEGKL 360
Query: 361 SLPWLLNKELGCINSPLQIDDDFCGQDFNQPLGGTVTIEGTPLFVDKDDGLTAVAAYDYR 420
SLPWLLNKELGCINSPLQIDDDFCGQDFNQPLGGTVTIEGTPLFVDKDDGLTAVAAYDYR
Sbjct: 361 SLPWLLNKELGCINSPLQIDDDFCGQDFNQPLGGTVTIEGTPLFVDKDDGLTAVAAYDYR 420
Query: 421 GRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDLVLSPNHQYLYAMT 480
GRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDLVLSPNHQYLYAMT
Sbjct: 421 GRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDLVLSPNHQYLYAMT 480
Query: 481 EKQVTRVPVESCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRFAADLLQC 540
EKQVTRVPVESCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRFAADLLQC
Sbjct: 481 EKQVTRVPVESCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRFAADLLQC 540
Query: 541 VQLTVQPRNVSVTMSQVPLVLQAWNVPDLSAGVNCSFEDFTESESVLEDGRIHCRSPSAR 600
VQLTVQPRNVSVTMSQVPLVLQAWNVPDLSAGVNCSFEDFTESESVLEDGRIHCRSPSAR
Sbjct: 541 VQLTVQPRNVSVTMSQVPLVLQAWNVPDLSAGVNCSFEDFTESESVLEDGRIHCRSPSAR 600
Query: 601 EVAPITRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCSVHQSCLSCVNGSFPCHWCKYR 660
EVAPITRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCSVHQSCLSCVNGSFPCHWCKYR
Sbjct: 601 EVAPITRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCSVHQSCLSCVNGSFPCHWCKYR 660
Query: 661 HVCTHNVADCAFLEGRVNVSEDCPQILPSTQIYVPVGVVKPITLAARNLPQPQSGQRGYE 720
HVCTHNVADCAFLEGRVNVSEDCPQILPSTQIYVPVGVVKPITLAARNLPQPQSGQRGYE
Sbjct: 661 HVCTHNVADCAFLEGRVNVSEDCPQILPSTQIYVPVGVVKPITLAARNLPQPQSGQRGYE 720
Query: 721 CLFHIPGSPARVTALRFNSSSLQCQNSSYSYEGNDVSDLPVNLSVVWNGNFVIDNPQNIQ 780
CLFHIPGSPARVTALRFNSSSLQCQNSSYSYEGNDVSDLPVNLSVVWNGNFVIDNPQNIQ
Sbjct: 721 CLFHIPGSPARVTALRFNSSSLQCQNSSYSYEGNDVSDLPVNLSVVWNGNFVIDNPQNIQ 780
Query: 781 AHLYKCPALRESCGLCLKADPRFECGWCVAERRCSLRHHCAADTPASWMHARHGSSRCTD 840
AHLYKCPALRESCGLCLKADPRFECGWCVAERRCSLRHHCAADTPASWMHARHGSSRCTD
Sbjct: 781 AHLYKCPALRESCGLCLKADPRFECGWCVAERRCSLRHHCAADTPASWMHARHGSSRCTD 840
Query: 841 PKILKLSPETGPRQGGTRLTITGENLGLRFEDVRLGVRVGKVLCSPVESEYISAEQIVCE 900
PKILKLSPETGPRQGGTRLTITGENLGLRFEDVRLGVRVGKVLCSPVESEYISAEQIVCE
Sbjct: 841 PKILKLSPETGPRQGGTRLTITGENLGLRFEDVRLGVRVGKVLCSPVESEYISAEQIVCE 900
Query: 901 IGDASSVRAHDALVEVCVRDCSPHYRALSPKRFTFVTPTFYRVSPSRGPLSGGTWIGIEG 960
IGDASSVRAHDALVEVCVRDCSPHYRALSPKRFTFVTPTFYRVSPSRGPLSGGTWIGIEG
Sbjct: 901 IGDASSVRAHDALVEVCVRDCSPHYRALSPKRFTFVTPTFYRVSPSRGPLSGGTWIGIEG 960
Query: 961 SHLNAGSDVAVSVGGRPCSFSWRNSREIRCLTPPGQSPGSAPIIININRAQLTNPEVKYN 1020
SHLNAGSDVAVSVGGRPCSFSWRNSREIRCLTPPGQSPGSAPIIININRAQLTNPEVKYN
Sbjct: 961 SHLNAGSDVAVSVGGRPCSFSWRNSREIRCLTPPGQSPGSAPIIININRAQLTNPEVKYN 1020
Query: 1021 YTEDPTILRIDPEWSINSGGTLLTVTGTNLATVREPRIRAKYGGIERENGCLVYNDTTMV 1080
YTEDPTILRIDPEWSINSGGTLLTVTGTNLATVREPRIRAKYGGIERENGCLVYNDTTMV
Sbjct: 1021 YTEDPTILRIDPEWSINSGGTLLTVTGTNLATVREPRIRAKYGGIERENGCLVYNDTTMV 1080
Query: 1081 CRAPSVANPVRSPPELGERPDELGFVMDNVRSLLVLNSTSFLYYPDPVLEPLSPTGLLEL 1140
CRAPSVANPVRSPPELGERPDELGFVMDNVRSLLVLNSTSFLYYPDPVLEPLSPTGLLEL
Sbjct: 1081 CRAPSVANPVRSPPELGERPDELGFVMDNVRSLLVLNSTSFLYYPDPVLEPLSPTGLLEL 1140
Query: 1141 KPSSPLILKGRNLLPPAPGNSRLNYTVLIGSTPCTLTVSETQLLCEAPNLTGQHKVTVRA 1200
KPSSPLILKGRNLLPPAPGNSRLNYTVLIGSTPCTLTVSETQLLCEAPNLTGQHKVTVRA
Sbjct: 1141 KPSSPLILKGRNLLPPAPGNSRLNYTVLIGSTPCTLTVSETQLLCEAPNLTGQHKVTVRA 1200
Query: 1201 GGFEFSPGTLQVYSDSLLTLPAIVGIGGGGGLLLLVIVAVLIAYKRKSRDADRTLKRLQL 1260
GGFEFSPGTLQVYSDSLLTLPAIVGIGGGGGLLLLVIVAVLIAYKRKSRDADRTLKRLQL
Sbjct: 1201 GGFEFSPGTLQVYSDSLLTLPAIVGIGGGGGLLLLVIVAVLIAYKRKSRDADRTLKRLQL 1260
Query: 1261 QMDNLESRVALECKEAFAELQTDIHELTNDLDGAGIPFLDYRTYAMRVLFPGIEDHPVLK 1320
QMDNLESRVALECKEAFAELQTDIHELTNDLDGAGIPFLDYRTYAMRVLFPGIEDHPVLK
Sbjct: 1261 QMDNLESRVALECKEAFAELQTDIHELTNDLDGAGIPFLDYRTYAMRVLFPGIEDHPVLK 1320
Query: 1321 EMEVQANVEKSLTLFGQLLTKKHFLLTFIRTLEAQRSFSMRDRGNVASLIMTALQGEMEY 1380
EMEVQANVEKSLTLFGQLLTKKHFLLTFIRTLEAQRSFSMRDRGNVASLIMTALQGEMEY
Sbjct: 1321 EMEVQANVEKSLTLFGQLLTKKHFLLTFIRTLEAQRSFSMRDRGNVASLIMTALQGEMEY 1380
Query: 1381 ATGVLKQLLSDLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFM 1440
ATGVLKQLLSDLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFM
Sbjct: 1381 ATGVLKQLLSDLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFM 1440
Query: 1441 LYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLNCVNPENENAPEVPVKGL 1500
LYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLNCVNPENENAPEVPVKGL
Sbjct: 1441 LYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLNCVNPENENAPEVPVKGL 1500
Query: 1501 DCDTVTQAKEKLLDAAYKGVPYSQRPKAADMDLEWRQGRMARIILQDEDVTTKIDNDWKR 1560
DCDTVTQAKEKLLDAAYKGVPYSQRPKAADMDLEWRQGRMARIILQDEDVTTKIDNDWKR
Sbjct: 1501 DCDTVTQAKEKLLDAAYKGVPYSQRPKAADMDLEWRQGRMARIILQDEDVTTKIDNDWKR 1560
Query: 1561 LNTLAHYQVTDGSSVALVPKQTSAYNISNSSTFTKSLSRYESMLRTASSPDSLRSRTPMI 1620
LNTLAHYQVTDGSSVALVPKQTSAYNISNSSTFTKSLSRYESMLRTASSPDSLRSRTPMI
Sbjct: 1561 LNTLAHYQVTDGSSVALVPKQTSAYNISNSSTFTKSLSRYESMLRTASSPDSLRSRTPMI 1620
Query: 1621 TPDLESGTKLWHLVKNHDHLDQREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFS 1680
TPDLESGTKLWHLVKNHDHLDQREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFS
Sbjct: 1621 TPDLESGTKLWHLVKNHDHLDQREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFS 1680
Query: 1681 TAHRGSALPLAIKYMFDFLDEQADKHQIHDADVRHTWKSNCLPLRFWVNVIKNPQFVFDI 1740
TAHRGSALPLAIKYMFDFLDEQADKHQIHDADVRHTWKSNCLPLRFWVNVIKNPQFVFDI
Sbjct: 1681 TAHRGSALPLAIKYMFDFLDEQADKHQIHDADVRHTWKSNCLPLRFWVNVIKNPQFVFDI 1740
Query: 1741 HKNSITDACLSVVAQTFMDSCSTSEHKLGKDSPSNKLLYAKDIPNYKSWVERYYADIAKM 1800
HKNSITDACLSVVAQTFMDSCSTSEHKLGKDSPSNKLLYAKDIPNYKSWVERYYADIAKM
Sbjct: 1741 HKNSITDACLSVVAQTFMDSCSTSEHKLGKDSPSNKLLYAKDIPNYKSWVERYYADIAKM 1800
Query: 1801 PAISDQDMSAYLAEQSRLHLSQFNSMSALHEIYSYITKYKDEILAALEKDEQARRQRLRS 1860
PAISDQDMSAYLAEQSRLHLSQFNSMSALHEIYSYITKYKDEILAALEKDEQARRQRLRS
Sbjct: 1801 PAISDQDMSAYLAEQSRLHLSQFNSMSALHEIYSYITKYKDEILAALEKDEQARRQRLRS 1860
Query: 1861 KLEQVVDTMALSS 1873
KLEQVVDTMALSS
Sbjct: 1861 KLEQVVDTMALSS 1873
>gi|59710104 plexin A3 [Homo sapiens]
Length = 1871
Score = 2550 bits (6608), Expect = 0.0
Identities = 1249/1859 (67%), Positives = 1482/1859 (79%), Gaps = 11/1859 (0%)
Query: 17 PFRTFSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPP 76
PFR F +D LTHL VH TGEV+VGAVNR++KL+ NLT LRAHVTGPVEDN +CYPPP
Sbjct: 22 PFRAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAPNLTELRAHVTGPVEDNARCYPPP 81
Query: 77 SVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHY 136
S++ C H L DN+NKLLL+DYAA RL+ACGS QGICQFLRLDDLFKLGEPHHRKEHY
Sbjct: 82 SMRVCAHRLAPVDNINKLLLIDYAARRLVACGSIWQGICQFLRLDDLFKLGEPHHRKEHY 141
Query: 137 LSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSSRRLMANEEDADMFGFV 196
LS QE SMAGV++ GQG +KLFVGT +DGKSEYFPTLSSR+L+++E+ ADMF V
Sbjct: 142 LSGAQEPDSMAGVIVE--QGQGPSKLFVGTAVDGKSEYFPTLSSRKLISDEDSADMFSLV 199
Query: 197 YQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHFFT 256
YQDEFVSSQ+KIPSDTLS +PAFDIYY+Y F S FVY+LTLQLDTQ T D AGE FFT
Sbjct: 200 YQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSASFVYFLTLQLDTQQTLLDTAGEKFFT 259
Query: 257 SKIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVLFT 316
SKIVR+C D +FYSYVEFPIGC GVEYRLVQ A+L++PG LA LG+ DEDVLFT
Sbjct: 260 SKIVRMCAGDSEFYSYVEFPIGCSWRGVEYRLVQSAHLAKPGLLLAQALGVPADEDVLFT 319
Query: 317 VFAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSCYRGEGKLSLPWLLNKELGCINSP 376
+F+QGQKNR PP+++ LCLFTL I I+ RIQSCYRGEG L+LPWLLNKEL CIN+P
Sbjct: 320 IFSQGQKNRASPPRQTILCLFTLSNINAHIRRRIQSCYRGEGTLALPWLLNKELPCINTP 379
Query: 377 LQIDDDFCGQDFNQPLGGTVTIEGTPLFVDKDDGLTAVAAYDYRGRTVVFAGTRSGRIRK 436
+QI+ +FCG NQPLGG IEG PL D DG+ +VAAY YR +VVF GTRSG ++K
Sbjct: 380 MQINGNFCGLVLNQPLGGLHVIEGLPLLADSTDGMASVAAYTYRQHSVVFIGTRSGSLKK 439
Query: 437 ILVDLSNPGGRPALAYESVVAQEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVESCVQYT 496
+ VD G + A YE+V +GSPILRDL+ SP+H+++Y ++EKQV+++PVE+C QY
Sbjct: 440 VRVD----GFQDAHLYETVPVVDGSPILRDLLFSPDHRHIYLLSEKQVSQLPVETCEQYQ 495
Query: 497 SCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRFAADLLQCVQLTVQPRNVSVTMSQ 556
SC CLGS DPHCGWCVL C R AC A P FA +L +CVQ+ V+P NVSVT
Sbjct: 496 SCAACLGSGDPHCGWCVLRHRCCREGACLGASAPHGFAEELSKCVQVRVRPNNVSVTSPG 555
Query: 557 VPLVLQAWNVPDLSAGVNCSFEDFTESESVL-EDGRIHCRSPSAREVAPITRGQGDQRVV 615
V L + NVPDLSAGV+C+FE E+E+VL G + C SPS +E+ +TRG G R V
Sbjct: 556 VQLTVTLHNVPDLSAGVSCAFEAAAENEAVLLPSGELLCPSPSLQELRALTRGHGATRTV 615
Query: 616 KLYLKSKETGKKFASVDFVFYNCSVHQSCLSCVNGSFPCHWCKYRHVCTHNVADCAFLEG 675
+L L SKETG +FA DFVFYNCSV QSC+SCV +PCHWCKYRH CT +C+F EG
Sbjct: 616 RLQLLSKETGVRFAGADFVFYNCSVLQSCMSCVGSPYPCHWCKYRHTCTSRPHECSFQEG 675
Query: 676 RVNVSEDCPQILPSTQIYVPVGVVKPITLAARNLPQPQSGQRGYECLFHIPGSPARVTAL 735
RV+ E CP+ILPS + +PVGV++P+TL A+NLPQPQSGQ+ YEC+ + G RV A+
Sbjct: 676 RVHSPEGCPEILPSGDLLIPVGVMQPLTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPAV 735
Query: 736 RFNSSSLQCQNSSYSYEGNDVSDLPVNLSVVWNGNFVIDNPQNIQAHLYKCPALRESCGL 795
RFNSSS+QCQN+SYSYEG++ D ++ SVVW+G+F ID P + +A LYKC A R SCGL
Sbjct: 736 RFNSSSVQCQNASYSYEGDEHGDTELDFSVVWDGDFPIDKPPSFRALLYKCWAQRPSCGL 795
Query: 796 CLKADPRFECGWCVAERRCSLRHHCAADTPASWMHARHGSSRCTDPKILKLSPETGPRQG 855
CLKADPRF CGWC++E RC LR HC A +WMH +RC+ P+I ++ P GP++G
Sbjct: 796 CLKADPRFNCGWCISEHRCQLRTHCPAPK-TNWMHLSQKGTRCSHPRITQIHPLVGPKEG 854
Query: 856 GTRLTITGENLGLRFEDVRLGVRVGKVLCSPVESEYISAEQIVCEIGDASSVRAHDALVE 915
GTR+TI G+NLGL +V G+RV V C+ + +EYISAE+IVCE+ ++ VE
Sbjct: 855 GTRVTIVGDNLGLLSREV--GLRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGPVE 912
Query: 916 VCVRDCSPHYRALSPKRFTFVTPTFYRVSPSRGPLSGGTWIGIEGSHLNAGSDVAVSVGG 975
+CV DCS +R S + ++FVTPTF +VSPSRGP SGGT + I GS L+AGS V V+V
Sbjct: 913 LCVGDCSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTVTVRD 972
Query: 976 RPCSFSWRNSREIRCLTPPGQ-SPGSAPIIININRAQLTNPEVKYNYTEDPTILRIDPEW 1034
C F R+++ I C++P P API + I+RA +++P + Y YT+DPT+ R++P W
Sbjct: 973 SECQFVRRDAKAIVCISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTW 1032
Query: 1035 SINSGGTLLTVTGTNLATVREPRIRAKYGGIERENGCLVYNDTTMVCRAPSVANPVRSPP 1094
SI +G T +TV+GT+L TV+EPR+RAKY GIE N C V NDT M+C+AP + P
Sbjct: 1033 SIINGSTAITVSGTHLLTVQEPRVRAKYRGIETTNTCQVINDTAMLCKAPGIFLGRPQPR 1092
Query: 1095 ELGERPDELGFVMDNVRSLLVLNSTSFLYYPDPVLEPLSPTGLLELKPSSPLILKGRNLL 1154
GE PDE GF++D+V++ LN +SF YYPDP EPL P+G+L++KP S ++LKG+NL+
Sbjct: 1093 AQGEHPDEFGFLLDHVQTARSLNRSSFTYYPDPSFEPLGPSGVLDVKPGSHVVLKGKNLI 1152
Query: 1155 PPAPGNSRLNYTVLIGSTPCTLTVSETQLLCEAPNLTGQHKVTVRAGGFEFSPGTLQVYS 1214
P A G+SRLNYTVLIG PC+LTVS+TQLLC++P+ TG+ V V GG EF GTL + +
Sbjct: 1153 PAAAGSSRLNYTVLIGGQPCSLTVSDTQLLCDSPSQTGRQPVMVLVGGLEFWLGTLHISA 1212
Query: 1215 DSLLTLPAIVGIGGGGGLLLLVIVAVLIAYKRKSRDADRTLKRLQLQMDNLESRVALECK 1274
+ LTLPA++G+ GGGLLLL I AVL+AYKRK++DADRTLKRLQLQMDNLESRVALECK
Sbjct: 1213 ERALTLPAMMGLAAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLESRVALECK 1272
Query: 1275 EAFAELQTDIHELTNDLDGAGIPFLDYRTYAMRVLFPGIEDHPVLKEMEVQANVEKSLTL 1334
EAFAELQTDI+ELTN +D IPFLDYRTYA+RVLFPGIE HPVLKE++ NVEK+L L
Sbjct: 1273 EAFAELQTDINELTNHMDEVQIPFLDYRTYAVRVLFPGIEAHPVLKELDTPPNVEKALRL 1332
Query: 1335 FGQLLTKKHFLLTFIRTLEAQRSFSMRDRGNVASLIMTALQGEMEYATGVLKQLLSDLIE 1394
FGQLL + F+LTFI TLEAQ SFSMRDRG VASL M ALQ ++YATG+LKQLL+DLIE
Sbjct: 1333 FGQLLHSRAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLLKQLLADLIE 1392
Query: 1395 KNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFMLYCAIKQQMEKGPI 1454
KNLESKNHPKLLLRRTESVAEKMLTNWFTFLL+KFLKECAGEPLF+LYCAIKQQMEKGPI
Sbjct: 1393 KNLESKNHPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAIKQQMEKGPI 1452
Query: 1455 DAITGEARYSLSEDKLIRQQIDYKTLTLNCVNPENENAPEVPVKGLDCDTVTQAKEKLLD 1514
DAITGEARYSLSEDKLIRQQIDYKTLTL+CV PENE + +VPVK L+CD++TQAK+KLLD
Sbjct: 1453 DAITGEARYSLSEDKLIRQQIDYKTLTLHCVCPENEGSAQVPVKVLNCDSITQAKDKLLD 1512
Query: 1515 AAYKGVPYSQRPKAADMDLEWRQGRMARIILQDEDVTTKIDNDWKRLNTLAHYQVTDGSS 1574
YKG+PYSQRPKA DMDLEWRQGRM RIILQDEDVTTKI+ DWKRLN+LAHYQVTDGS
Sbjct: 1513 TVYKGIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLNSLAHYQVTDGSL 1572
Query: 1575 VALVPKQTSAYNISNSSTFTKSLSRYESMLRTASSPDSLRSRTPMITPDLESGTKLWHLV 1634
VALVPKQ SAYN++NS TFT+SLSRYES+LRTASSPDSLRSR PMITPD E+GTKLWHLV
Sbjct: 1573 VALVPKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSLRSRAPMITPDQETGTKLWHLV 1632
Query: 1635 KNHDHLDQREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKY 1694
KNHDH D REGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFET+FSTAHRGSALPLAIKY
Sbjct: 1633 KNHDHADHREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETVFSTAHRGSALPLAIKY 1692
Query: 1695 MFDFLDEQADKHQIHDADVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVA 1754
MFDFLDEQAD+ QI D DVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVA
Sbjct: 1693 MFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVA 1752
Query: 1755 QTFMDSCSTSEHKLGKDSPSNKLLYAKDIPNYKSWVERYYADIAKMPAISDQDMSAYLAE 1814
QTFMDSCSTSEH+LGKDSPSNKLLYAKDIPNYKSWVERYY DIAKM +ISDQDM AYL E
Sbjct: 1753 QTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMASISDQDMDAYLVE 1812
Query: 1815 QSRLHLSQFNSMSALHEIYSYITKYKDEILAALEKDEQARRQRLRSKLEQVVDTMALSS 1873
QSRLH S F+ +SAL+E+Y Y+TKY+ EIL AL++D R+ +LR KLEQ++ ++ S
Sbjct: 1813 QSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKLRQKLEQIISLVSSDS 1871
>gi|113722116 plexin A2 [Homo sapiens]
Length = 1894
Score = 2452 bits (6354), Expect = 0.0
Identities = 1204/1883 (63%), Positives = 1468/1883 (77%), Gaps = 22/1883 (1%)
Query: 1 MWAEAGLPRAGGGSQPPFRTFSAS--DWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLL 58
+W P AG P F TF + DW HL VH+ TG VYVGA+NR+YKL+GNLT+
Sbjct: 24 VWVLLAPPAAG---MPQFSTFHSENRDWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQ 80
Query: 59 RAHVTGPVEDNEKCYPPPSVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFL 118
AH TGP EDN+ CYPP VQ C L T+NVNKLL++DY+ NRLLACGS QG+C+ L
Sbjct: 81 VAHKTGPEEDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLL 140
Query: 119 RLDDLFKLGEPHHRKEHYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTL 178
RLDDLF L EP H+KEHYLSSV + G+M GV++ G KLF+GT +DGK +YFPTL
Sbjct: 141 RLDDLFILVEPSHKKEHYLSSVNKTGTMYGVIVRSEGEDG--KLFIGTAVDGKQDYFPTL 198
Query: 179 SSRRLMANEEDADMFGFVYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTL 238
SSR+L + E + M + +FVSS +KIPSDTL+ FDI+Y+Y F S FVY+LT+
Sbjct: 199 SSRKLPRDPESSAMLDYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFLTV 258
Query: 239 QLDT-QLTSPDAAGEHFFTSKIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRP 297
Q +T + + ++AG+ F+TS+IVRLC DDPKF+SYV P GC +AGVEYRL+Q AYL++P
Sbjct: 259 QPETPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYLAKP 318
Query: 298 GRALAHQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSCYRGE 357
G +LA + +DVLF +F++GQK PP +SALC F +RAI +IKER+QSCY+GE
Sbjct: 319 GDSLAQAFNITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQGE 378
Query: 358 GKLSLPWLLNKELGCINSPLQIDDDFCGQDFNQPLGGTVTIEGTPLFVDKDDGLTAVAAY 417
G L L WLL K++ C +P+ IDD+FCG D NQPLGG+ +EG L+ D +T+VA+Y
Sbjct: 379 GNLELNWLLGKDVQCTKAPVPIDDNFCGLDINQPLGGSTPVEGLTLYTTSRDRMTSVASY 438
Query: 418 DYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESV-VAQEGSPILRDLVLSPNHQYL 476
Y G +VVF GT+SG+++KI D GG + YE V V ++GSPILRD+ S + +YL
Sbjct: 439 VYNGYSVVFVGTKSGKLKKIRADGPPHGG---VQYEMVSVLKDGSPILRDMAFSIDQRYL 495
Query: 477 YAMTEKQVTRVPVESCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRFAAD 536
Y M+E+QVTRVPVESC QYT+C CL S DPHCGWC LH++CSRRD C++A EP RFAA
Sbjct: 496 YVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCSRRDKCQQAWEPNRFAAS 555
Query: 537 LLQCVQLTVQPRNVSVTMSQVPLVLQAWNVPDLSAGVNCSFEDFTESESVLEDGRIHCRS 596
+ QCV L V P ++SV+ L L + PDLSAG+ C+F + TE E + ++ C S
Sbjct: 556 ISQCVSLAVHPSSISVSEHSRLLSLVVSDAPDLSAGIACAFGNLTEVEGQVSGSQVICIS 615
Query: 597 PSAREVAPITRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCSVHQSCLSCVNGSFPCHW 656
P ++V I Q D ++L L+SKETGK F S +F FYNCS HQ CLSCVN +F CHW
Sbjct: 616 PGPKDVPVIPLDQ-DWFGLELQLRSKETGKIFVSTEFKFYNCSAHQLCLSCVNSAFRCHW 674
Query: 657 CKYRHVCTHNVADCAFLEGRVNVSEDCPQILPSTQIYVPVGVVKPITLAARNLPQPQSGQ 716
CKYR++CTH+ C+F EGR+N+SEDCPQ++P+ +I +PVG VKPITL ARNLPQPQSGQ
Sbjct: 675 CKYRNLCTHDPTTCSFQEGRINISEDCPQLVPTEEILIPVGEVKPITLKARNLPQPQSGQ 734
Query: 717 RGYECLFHIPGSPARVTALRFNSSSLQCQNSSYSYEGNDVSDLPVNLSVVWNGNFVIDNP 776
RGYEC+ +I G+ RV ALRFNSSS+QCQNSSY Y+G D+S+L V+ +VVWNGNF+IDNP
Sbjct: 735 RGYECVLNIQGAIHRVPALRFNSSSVQCQNSSYQYDGMDISNLAVDFAVVWNGNFIIDNP 794
Query: 777 QNIQAHLYKCPALRESCGLCLKADPRFECGWCVAERRCSLRHHCAADTPASWMHARHGSS 836
Q+++ HLYKC A RESCGLCLKAD +FECGWC ERRC+L HC + + + W+ +
Sbjct: 795 QDLKVHLYKCAAQRESCGLCLKADRKFECGWCSGERRCTLHQHCTSPS-SPWLDWSSHNV 853
Query: 837 RCTDPKILKLSPETGPRQGGTRLTITGENLGLRFEDVRLGVRVGKVLCSPVESEYISAEQ 896
+C++P+I ++ +GP +GGTR+TI G NLGL F ++ V+V V C+P+ EYI AEQ
Sbjct: 854 KCSNPQITEILTVSGPPEGGTRVTIHGVNLGLDFSEIAHHVQVAGVPCTPLPGEYIIAEQ 913
Query: 897 IVCEIGDASSVRAHDALVEVCVRDCSPHYRALSPKRFTFVTPTFYRVSPSRGPLSGGTWI 956
IVCE+G A V V +C+ +C P + S +++TFV P+ ++P RGP SGGT +
Sbjct: 914 IVCEMGHAL-VGTTSGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLNPIRGPESGGTMV 972
Query: 957 GIEGSHLNAGSDVAVSVGGRPCSFSWRNSREIRCLTPPGQSP-GSAPIIININRAQLTNP 1015
I G +L AGS VAV +G + C F R+ EI C++PP + G P+ ++++RA + +
Sbjct: 973 TITGHYLGAGSSVAVYLGNQTCEFYGRSMSEIVCVSPPSSNGLGPVPVSVSVDRAHVDS- 1031
Query: 1016 EVKYNYTEDPTILRIDPEWSINSGGTLLTVTGTNLATVREPRIRAKYGGIERENGCLVYN 1075
+++ Y +DP + RI+PEWSI SG T LT+TG NL ++EPRIR K+ G E N C V N
Sbjct: 1032 NLQFEYIDDPRVQRIEPEWSIASGHTPLTITGFNLDVIQEPRIRVKFNGKESVNVCKVVN 1091
Query: 1076 DTTMVCRAPSVANPVRSPPELGERPDELGFVMDNVRSLLVLNSTSFLYYPDPVLEPLSPT 1135
TT+ C APS+ R + ERPDE GFV +NV+SLL+ N T F+YYP+P E LSPT
Sbjct: 1092 TTTLTCLAPSLTTDYRPGLDTVERPDEFGFVFNNVQSLLIYNDTKFIYYPNPTFELLSPT 1151
Query: 1136 GLLELKPSSPLILKGRNLLPPAPGNSRLNYTVLIGSTPCTLTVSETQLLCEAPNLTGQHK 1195
G+L+ KP SP+ILKG+NL PPA G ++LNYTVLIG TPC +TVSETQLLCE PNLTGQHK
Sbjct: 1152 GVLDQKPGSPIILKGKNLCPPASGGAKLNYTVLIGETPCAVTVSETQLLCEPPNLTGQHK 1211
Query: 1196 VTVRAGGFEFSPGTLQVYSDSLLTLPAIVGIGGGGGLLLLVIVAVLIAYKRKSRDADRTL 1255
V V GG FSPG++ V SDSLLTLPAIV I GG LLL++++ VLIAYKRKSR+ D TL
Sbjct: 1212 VMVHVGGMVFSPGSVSVISDSLLTLPAIVSIAAGGSLLLIIVIIVLIAYKRKSRENDLTL 1271
Query: 1256 KRLQLQMDNLESRVALECKEAFAELQTDIHELTNDLDGAGIPFLDYRTYAMRVLFPGIED 1315
KRLQ+QMDNLESRVALECKEAFAELQTDI+ELT+DLD +GIP+LDYRTYAMRVLFPGIED
Sbjct: 1272 KRLQMQMDNLESRVALECKEAFAELQTDINELTSDLDRSGIPYLDYRTYAMRVLFPGIED 1331
Query: 1316 HPVLKEMEVQAN----VEKSLTLFGQLLTKKHFLLTFIRTLEAQRSFSMRDRGNVASLIM 1371
HPVL+E+EVQ N VEK+L LF QL+ K FLLTFIRTLE QRSFSMRDRGNVASLIM
Sbjct: 1332 HPVLRELEVQGNGQQHVEKALKLFAQLINNKVFLLTFIRTLELQRSFSMRDRGNVASLIM 1391
Query: 1372 TALQGEMEYATGVLKQLLSDLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLK 1431
T LQG +EYAT VLKQLLSDLI+KNLE+KNHPKLLLRRTESVAEKMLTNWF FLL+KFLK
Sbjct: 1392 TGLQGRLEYATDVLKQLLSDLIDKNLENKNHPKLLLRRTESVAEKMLTNWFAFLLHKFLK 1451
Query: 1432 ECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLNCVNPENEN 1491
ECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQI+YKTL LNCVNP+NEN
Sbjct: 1452 ECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIEYKTLILNCVNPDNEN 1511
Query: 1492 APEVPVKGLDCDTVTQAKEKLLDAAYKGVPYSQRPKAADMDLEWRQGRMARIILQDEDVT 1551
+PE+PVK L+CDT+TQ KEK+LDA YK VPYSQRP+A DMDLEWRQGR+AR++LQDED+T
Sbjct: 1512 SPEIPVKVLNCDTITQVKEKILDAVYKNVPYSQRPRAVDMDLEWRQGRIARVVLQDEDIT 1571
Query: 1552 TKIDNDWKRLNTLAHYQVTDGSSVALVPKQTSAYNISNSSTFTK-SLSRYESMLRTASSP 1610
TKI+ DWKRLNTL HYQV+D S VALVPKQTS+YNI S++ ++ S+SRY+S R SP
Sbjct: 1572 TKIEGDWKRLNTLMHYQVSDRSVVALVPKQTSSYNIPASASISRTSISRYDSSFRYTGSP 1631
Query: 1611 DSLRSRTPMITPDLESGTKLWHLVKNHDHLDQREGDRGSKMVSEIYLTRLLATKGTLQKF 1670
DSLRSR PMITPDLESG K+WHLVKNHDH DQ+EGDRGSKMVSEIYLTRLLATKGTLQKF
Sbjct: 1632 DSLRSRAPMITPDLESGVKVWHLVKNHDHGDQKEGDRGSKMVSEIYLTRLLATKGTLQKF 1691
Query: 1671 VDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHQIHDADVRHTWKSNCLPLRFWVNV 1730
VDDLFET+FST HRGSALPLAIKYMFDFLDEQAD+H IHD DVRHTWKSNCLPLRFWVNV
Sbjct: 1692 VDDLFETLFSTVHRGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNCLPLRFWVNV 1751
Query: 1731 IKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHKLGKDSPSNKLLYAKDIPNYKSWV 1790
IKNPQFVFDIHK SITDACLSVVAQTFMDSCSTSEH+LGKDSPSNKLLYAKDIP+YKSWV
Sbjct: 1752 IKNPQFVFDIHKGSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKSWV 1811
Query: 1791 ERYYADIAKMPAISDQDMSAYLAEQSRLHLSQFNSMSALHEIYSYITKYKDEILAALEKD 1850
ERYYADIAK+PAISDQDM+AYLAEQSRLH +FN +SAL+EIYSY++KY +E++ ALE+D
Sbjct: 1812 ERYYADIAKLPAISDQDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKYSEELIGALEQD 1871
Query: 1851 EQARRQRLRSKLEQVVDTMALSS 1873
EQARRQRL K+EQ+++ M++ S
Sbjct: 1872 EQARRQRLAYKVEQLINAMSIES 1894
>gi|157738645 plexin A4 isoform 1 [Homo sapiens]
Length = 1894
Score = 2442 bits (6330), Expect = 0.0
Identities = 1199/1853 (64%), Positives = 1454/1853 (78%), Gaps = 14/1853 (0%)
Query: 27 GLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPPSVQSCPHGLG 86
G HLVV E+TG +Y+GAVNRIYKLS +L +L H TGP EDN KCYPP VQ+C L
Sbjct: 50 GFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLT 109
Query: 87 STDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSVQEAGSM 146
+T+NVNK+LL+DY NRL+ACGS QGIC+ LRL+DLFKLGEP+H+KEHYLS V E+GS+
Sbjct: 110 TTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSV 169
Query: 147 AGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSSRRLMANEEDADMFGFVYQDEFVSSQL 206
GV+++ KLF+ T +DGK EYFPT+SSR+L N E MF +V+ DEFV+S +
Sbjct: 170 FGVIVSY--SNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMI 227
Query: 207 KIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHFFTSKIVRLCVDD 266
KIPSDT + P FDIYYVY F S FVY+LTLQ + E +TSK+VRLC +D
Sbjct: 228 KIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKED 287
Query: 267 PKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVLFTVFAQGQKNRV 326
F SYVE PIGCE++GVEYRL+Q AYLS+ G L LG+ D+D+LFTVF++GQK ++
Sbjct: 288 TAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKM 347
Query: 327 KPPKESALCLFTLRAIKEKIKERIQSCYRGEGKLSLPWLLNKELGCINSPLQIDDDFCGQ 386
K ESALC+F L+ I ++IKER+QSCYRGEG L L WL K++ C ++ L IDD+FCG
Sbjct: 348 KSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGL 407
Query: 387 DFNQPLGGTVTIEGTPLFVDKDDGLTAVAAYDYRGRTVVFAGTRSGRIRKILVDLSNPGG 446
D N PLG + + G P+F + D +T+V AY Y+ ++ F GT+SG+++KI VD P G
Sbjct: 408 DMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVD--GPRG 465
Query: 447 RPALAYESVVAQEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVESCVQYTSCELCLGSRD 506
AL YE+V + P+LRD+ S +H+ LY M+E+Q+TRVPVESC QY SC CLGS D
Sbjct: 466 N-ALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGSGD 524
Query: 507 PHCGWCVLHSICSRRDACERADEPQRFAADLLQCVQLTVQPRNVSVTMSQVPLVLQAWNV 566
PHCGWCVLH+ C+R++ CER+ EP+RFA+++ QCV+LTV P N+SV+ V LVL+ +NV
Sbjct: 525 PHCGWCVLHNTCTRKERCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETYNV 584
Query: 567 PDLSAGVNCSFEDFTESESVLEDGRIHCRSPSAREVAPITRGQGDQRVVKLYLKSKETGK 626
P+LSAGVNC+FED +E + ++ +I C SP+A+EV I GD VV+L LKSKETG
Sbjct: 585 PELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKETGM 644
Query: 627 KFASVDFVFYNCSVHQSCLSCVNGSFPCHWCKYRHVCTHNVADCAFLEGRVNVSEDCPQI 686
FAS FVFYNCSVH SCLSCV + CHWCKYRHVCTH+ C+F EGRV + EDCPQ+
Sbjct: 645 TFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCPQL 704
Query: 687 LPSTQIYVPVGVVKPITLAARNLPQPQSGQRGYECLFHIPGSPARVTALRFNSSSLQCQN 746
L +I VPV V+KPITL A+NLPQPQSGQRGYEC+ +I GS RV ALRFNSSS+QCQN
Sbjct: 705 LRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQCQN 764
Query: 747 SSYSYEGNDVSDLPVNLSVVWNGNFVIDNPQNIQAHLYKCPALRESCGLCLKADPRFECG 806
+SYSYEG ++++LPV L+VVWNG+F IDNP + HLYKC A+RESCGLCLKADP F CG
Sbjct: 765 TSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFACG 824
Query: 807 WCVAERRCSLRHHCAADTPASWMHARHGSSRCTDPKILKLSPETGPRQGGTRLTITGENL 866
WC +C+LR HC A + W+ S+CT+P+I ++ P TGPR+GGT++TI GENL
Sbjct: 825 WCQGPGQCTLRQHCPAQ-ESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGENL 883
Query: 867 GLRFEDVRLGVRVGKVLCSPVESEYISAEQIVCEIGDASSVRAHDALVEVCVRDCSPHYR 926
GL F D+ V+V V CSP+ YI AEQIVCE+G+A + H VE+CV C P +
Sbjct: 884 GLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQ-HAGFVEICVAVCRPEFM 942
Query: 927 ALSPKRFTFVTPTFYRVSPSRGPLSGGTWIGIEGSHLNAGSDVAVSVGGRPCSFSWRNSR 986
A S + + F+T T + PSRGP+SGGT + I G++LNAGS+V V G +PC F R+
Sbjct: 943 ARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPS 1002
Query: 987 EIRCLTPPGQSPGSAPIIININRAQLTNPEVKYNYTEDPTILRIDPEWSINSGGTLLTVT 1046
I C T + + ++RA++ + ++ + Y EDPTI+RI+PEWSI SG T + V
Sbjct: 1003 YIVCNTTSSDEVLEMKVSVQVDRAKI-HQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVW 1061
Query: 1047 GTNLATVREPRIRAKYGGIERENGCLVYNDTTMVCRAPSVANPVRSPPELGERPDELGFV 1106
GT+L ++ P+IRAK+GG E N C V N T M C+AP++A +L ERP+E GF+
Sbjct: 1062 GTHLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFI 1121
Query: 1107 MDNVRSLLVLNSTSFLYYPDPVLEPLSPTGLLELKPSSPLILKGRNLLPP-APGNSRLNY 1165
+DNV+SLL+LN T+F YYP+PV E P+G+LELKP +P+ILKG+NL+PP A GN +LNY
Sbjct: 1122 LDNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNY 1181
Query: 1166 TVLIGSTPCTLTVSETQLLCEAPNLTGQHKVTVRAGGFEFSPGTLQVYSDSLLTLPAIVG 1225
TVL+G PCT+TVS+ QLLCE+PNL G+HKV R GG E+SPG + + DS L+LPAIV
Sbjct: 1182 TVLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVS 1241
Query: 1226 IGGGGGLLLLVIVAVLIAYKRKSRDADRTLKRLQLQMDNLESRVALECKEAFAELQTDIH 1285
I GGLL++ IVAVLIAYKRKSR++D TLKRLQ+QMDNLESRVALECKEAFAELQTDIH
Sbjct: 1242 IAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIH 1301
Query: 1286 ELTNDLDGAGIPFLDYRTYAMRVLFPGIEDHPVLKEMEV----QANVEKSLTLFGQLLTK 1341
ELT+DLDGAGIPFLDYRTY MRVLFPGIEDHPVL+++EV Q VEK L LF QL+
Sbjct: 1302 ELTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINN 1361
Query: 1342 KHFLLTFIRTLEAQRSFSMRDRGNVASLIMTALQGEMEYATGVLKQLLSDLIEKNLESKN 1401
K FLL+FIRTLE+QRSFSMRDRGNVASLIMT LQ ++EYAT VLKQLL+DLI+KNLESKN
Sbjct: 1362 KVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKN 1421
Query: 1402 HPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEA 1461
HPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLF L+CAIKQQMEKGPIDAITGEA
Sbjct: 1422 HPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEA 1481
Query: 1462 RYSLSEDKLIRQQIDYKTLTLNCVNPENENAPEVPVKGLDCDTVTQAKEKLLDAAYKGVP 1521
RYSLSEDKLIRQQIDYKTL L+CV+P+N N+PEVPVK L+CDT+TQ KEK+LDA +K VP
Sbjct: 1482 RYSLSEDKLIRQQIDYKTLVLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVP 1541
Query: 1522 YSQRPKAADMDLEWRQGRMARIILQDEDVTTKIDNDWKRLNTLAHYQVTDGSSVALVPKQ 1581
S RPKAADMDLEWRQG AR+ILQDED+TTKI+NDWKRLNTLAHYQV DGS VALV KQ
Sbjct: 1542 CSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQ 1601
Query: 1582 TSAYNISNSSTFTK-SLSRYESMLRTASSPDSLRSRTPMITPDLESGTKLWHLVKNHDHL 1640
+AYN N+ST ++ S S+YE+M+R SPDSLRSRTPMITPDLESG K+WHLVKNH+H
Sbjct: 1602 VTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHG 1661
Query: 1641 DQREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLD 1700
DQ+EGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLD
Sbjct: 1662 DQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLD 1721
Query: 1701 EQADKHQIHDADVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTFMDS 1760
EQADKH IHD VRHTWKSNCLPLRFWVN+IKNPQFVFDIHKNSITDACLSVVAQTFMDS
Sbjct: 1722 EQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDS 1781
Query: 1761 CSTSEHKLGKDSPSNKLLYAKDIPNYKSWVERYYADIAKMPAISDQDMSAYLAEQSRLHL 1820
CSTSEH+LGKDSPSNKLLYAKDIP+YK+WVERYY+DI KMPAISDQDM+AYLAEQSR+H+
Sbjct: 1782 CSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHM 1841
Query: 1821 SQFNSMSALHEIYSYITKYKDEILAALEKDEQARRQRLRSKLEQVVDTMALSS 1873
++FN+MSAL EI+SY+ KY +EIL L+ D+Q +Q+L KLEQV+ M+L S
Sbjct: 1842 NEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS 1894
>gi|253795481 plexin B3 isoform 2 [Homo sapiens]
Length = 1932
Score = 955 bits (2468), Expect = 0.0
Identities = 662/1958 (33%), Positives = 982/1958 (50%), Gaps = 219/1958 (11%)
Query: 21 FSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPPSVQS 80
FSA + L HL + G +YVGAVNR+++LS L L VTGPV D+ C P
Sbjct: 70 FSAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPDCVPFRDPAE 129
Query: 81 CPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSV 140
CP TDN N+LLL+ A L+ACG QG+C+ RL D+ E ++ E
Sbjct: 130 CPQAQ-LTDNANQLLLVSSRAQELVACGQVRQGVCETRRLGDV---AEVLYQAEDPGDGQ 185
Query: 141 QEAGSMAGVLIAG--PPGQGQAKLFVGTPIDGK-SEYFPTLSSRRLMANEEDADMFGFVY 197
A + GV G P G+ L V + GK S P L+ R+L ++ +
Sbjct: 186 FVAANTPGVATVGLVVPLPGRDLLLVARGLAGKLSAGVPPLAIRQLAGSQP--------F 237
Query: 198 QDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHFFTS 257
E + + + F ++ YV +F + Y++ A + + S
Sbjct: 238 SSEGLGRLV------VGDFSDYNNSYVGAFADARSAYFV-------FRRRGARAQAEYRS 284
Query: 258 KIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVLFTV 317
+ R+C+ D YSYVE P+ C+ G L+Q A+L+ PG L V
Sbjct: 285 YVARVCLGDTNLYSYVEVPLACQGQG----LIQAAFLA-PGTLLG--------------V 325
Query: 318 FAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSCYRGEGK-LSLPWLLNKELG----C 372
FA G + ++ALC F + + +++ + CY G+ S E G C
Sbjct: 326 FAAGPRGT-----QAALCAFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRC 380
Query: 373 INSPLQIDDDF-CGQDFN-QPLGGTVTIEGTPLFVDKDDGLTAVAAYDYRGRTVVFAGTR 430
+ PL + + CG + P+ G +E PL + ++AVAA G + F G
Sbjct: 381 VTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPL-LKLGQPVSAVAALQADGHMIAFLGDT 439
Query: 431 SGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVE 490
G++ K+ + G + + + V GS I DL+L + +LY +T QV R+PV
Sbjct: 440 QGQLYKVFLH----GSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVA 495
Query: 491 SCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRFAADLLQ---C--VQLTV 545
+C Q+ C CL ++DP CGWCVL C+R+ C RA + ++ + C +Q +
Sbjct: 496 ACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLL 555
Query: 546 QPRNVSVTMSQVPLVLQAWNVPDLSAGVNCSFEDFTESESVLEDGRIHCRSPSAREVAPI 605
+ QV L + + D +C+F D+ +S + +E + C +P +V P+
Sbjct: 556 PGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDY-DSLAHVEGPHVACVTPPQDQV-PL 613
Query: 606 TRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCSVHQS------CLSCVNGSFPCHWCKY 659
D V L L ++ A+ +F FY+CS Q+ C +CV + CHWC
Sbjct: 614 NPPGTDHVTVPLALMFEDV--TVAATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQ 671
Query: 660 RHVCTHN---------VADCAFLEGRVNVSEDCPQI--LPSTQIYVPVGVVKPITLAARN 708
C + + ++ +V CPQ+ L + VPVG + L RN
Sbjct: 672 SSHCVYGEHCPEGERTIYSAQEVDIQVRGPGACPQVEGLAGPHL-VPVGWESHLALRVRN 730
Query: 709 LPQPQSGQRGYECLFHIPGS----PARVTALRFNSSSLQCQNSSYSYEGNDVSDLPVNLS 764
L + + C +PG PA + +S + CQ + Y +LPV +
Sbjct: 731 LQHFRGLPASFHCWLELPGELRGLPATLEETAGDSGLIHCQAHQF-YPSMSQRELPVPIY 789
Query: 765 VVWNGNFVIDNPQNIQAHLYKCPALRESCGLCLKADPRFECGWCVAERRCSLRHHCAADT 824
V +DN + LY C C C A+ C WC A+ + + R+
Sbjct: 790 VTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAANRSLGCLWC-ADGQPACRYGPLCPP 848
Query: 825 PASWMHARHGSSRCTDPKILKLSPETGPRQGGTRLTITGENLGLRFEDVRLGVRVGKVLC 884
A + C P I + P TGP +GG LTI G NLG F DV+ V V C
Sbjct: 849 GAVEL-------LCPAPSIDAVEPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPC 901
Query: 885 SPVESEYISAEQIVCEIGDASSVRAHDALVEVCVRDCSPHYRALSPKRFTFVTPTFYRVS 944
+P S Y ++ +IVC A + V V ++ P +S + FT+ P +S
Sbjct: 902 NPEPSLYRTSARIVCVTSPAPN--GTTGPVRVAIKSQPP---GISSQHFTYQDPVLLSLS 956
Query: 945 PSRGPLSGGTWIGIEGSHLNAGSDVAVSVGGRPCSFSWRNSRE-IRCLTPPGQSPGSAPI 1003
P GP +GGT + I G HL G + + VGG+PC E I C T P +PG A +
Sbjct: 957 PRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCPEAIVCRTRPQAAPGEAAV 1016
Query: 1004 IININRAQLTNPEVKYNYTEDPTILRIDPEWSINSGGTLLTVTGTNLATVREPRIRA--- 1060
++ AQ T + YT +P ++ +P S GG L+ V GT L V+ P +
Sbjct: 1017 LVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRVRGTGLDVVQRPLLSVWLE 1076
Query: 1061 --------------------------------KYGG--IERENGCLVYNDTTMVCRAPSV 1086
+ GG ++ C V + + ++CR+P+V
Sbjct: 1077 ADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCSTVCSVNSSSLLLCRSPAV 1136
Query: 1087 ANPVRSPPELGERPDELGFVMDNVRSLLVLNS--TSFLYYPDPVLEPLS---PTGLLELK 1141
P R+ P+ + F +DNV+ S FLY P+P L PLS P LK
Sbjct: 1137 --PDRAHPQ------RVFFTLDNVQVDFASASGGQGFLYQPNPRLAPLSREGPARPYRLK 1188
Query: 1142 PSSPLILKGRNLLPPAPGNSRLNYTVLIGSTPCTL-TVSETQLLCEAP-------NLTGQ 1193
P L ++G L G S+ V IG C + T++ T L CE P N +G
Sbjct: 1189 PGHVLDVEGEGL---NLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHAPQPANGSGL 1245
Query: 1194 HKVTVRAGGFEFSPGTLQVYSD---SLLTLPAIVGIGGGGGLLLLVIVAVLIAYKRKSRD 1250
+ V+ G + + G +Q ++ S + A G+G G +L+ ++ + + Y+ KS+
Sbjct: 1246 PQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLTLMYRHKSKQ 1305
Query: 1251 ADRTLKRLQLQMDNLESRVALECKEAFAELQTDIHELTNDLDGAGIPFLDYRTYAMRVLF 1310
A R +++ +Q+++LE+ V +C++ F +L T++ +L++DL+G+GIPFLDYRTYA R F
Sbjct: 1306 ALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDYRTYAERAFF 1365
Query: 1311 PGIEDHPVLKEMEVQ------ANVEKSLTLFGQLLTKKHFLLTFIRTLEAQRSFSMRDRG 1364
PG P+ + E A V + LT LL K FLLT I TLE Q SFS RDR
Sbjct: 1366 PGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRC 1425
Query: 1365 NVASLIMTALQGEMEYATGVLKQLLSDLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTF 1424
+VASL+ AL G++EY T +++ LL DL + +PKL+LRRTE++ EK+LTNW +
Sbjct: 1426 HVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVH--RNPKLMLRRTETMVEKLLTNWLSI 1483
Query: 1425 LLYKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLNC 1484
LY FL+E AGEPL+ML+ AI+ Q++KGP+DA+TG+A+ +L++ +L+R+ ++++ LTL
Sbjct: 1484 CLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQPLTLMV 1543
Query: 1485 -VNPENENAP------EVPVKGLDCDTVTQAKEKLLDAAYKGVPYSQRPKAADMDLEWRQ 1537
V P A VP + LD DT+TQ KEK+LD YKG P+SQRP +DLEWR
Sbjct: 1544 LVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYKGTPFSQRPSVHALDLEWRS 1603
Query: 1538 GRMARIILQDEDVTTKIDNDWKRLNTLAHYQVTDGSSVALVPKQTSAYNISNSSTFTKSL 1597
G + L DED+T+ N WKRLNTL HY+V DG++V LVP+ + ST ++SL
Sbjct: 1604 GLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQ------LHRGSTISQSL 1657
Query: 1598 SRYESMLRTASSPDSLRSRTPMITPDLESGTKLWHLVKNHDH----------LDQREGDR 1647
++ L P + E G LWHLVK + L +RE R
Sbjct: 1658 AQR----------CPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPAR 1707
Query: 1648 GSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHQ 1707
+K + EIYLTRLL+ KGTLQKFVDD F+ I S +P+A+KY+FD LDE A+KH
Sbjct: 1708 -AKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSV---NRPIPIAVKYLFDLLDELAEKHG 1763
Query: 1708 IHDADVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHK 1767
I D H WK+N L LRFWVN +KNPQ +FD+ + DA L+V+AQTF+DSC+TSEHK
Sbjct: 1764 IEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHK 1823
Query: 1768 LGKDSPSNKLLYAKDIPNYKSWVERYYADIAKMPAISDQDMSAYLAEQSRLHLSQFNSMS 1827
+G+DSP NKLLYA++IP YK VERYYADI + S Q+M++ LAE S + S + +
Sbjct: 1824 VGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLE 1883
Query: 1828 ALHEIYSYITKYKDEILAALEKDEQARRQRLRSKLEQV 1865
AL E+Y++I +Y D+I++ALE+D ++ +L +L+QV
Sbjct: 1884 ALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQV 1921
>gi|29336063 plexin B3 isoform 1 [Homo sapiens]
Length = 1909
Score = 955 bits (2468), Expect = 0.0
Identities = 662/1958 (33%), Positives = 982/1958 (50%), Gaps = 219/1958 (11%)
Query: 21 FSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPPSVQS 80
FSA + L HL + G +YVGAVNR+++LS L L VTGPV D+ C P
Sbjct: 47 FSAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPDCVPFRDPAE 106
Query: 81 CPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSV 140
CP TDN N+LLL+ A L+ACG QG+C+ RL D+ E ++ E
Sbjct: 107 CPQAQ-LTDNANQLLLVSSRAQELVACGQVRQGVCETRRLGDV---AEVLYQAEDPGDGQ 162
Query: 141 QEAGSMAGVLIAG--PPGQGQAKLFVGTPIDGK-SEYFPTLSSRRLMANEEDADMFGFVY 197
A + GV G P G+ L V + GK S P L+ R+L ++ +
Sbjct: 163 FVAANTPGVATVGLVVPLPGRDLLLVARGLAGKLSAGVPPLAIRQLAGSQP--------F 214
Query: 198 QDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHFFTS 257
E + + + F ++ YV +F + Y++ A + + S
Sbjct: 215 SSEGLGRLV------VGDFSDYNNSYVGAFADARSAYFV-------FRRRGARAQAEYRS 261
Query: 258 KIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVLFTV 317
+ R+C+ D YSYVE P+ C+ G L+Q A+L+ PG L V
Sbjct: 262 YVARVCLGDTNLYSYVEVPLACQGQG----LIQAAFLA-PGTLLG--------------V 302
Query: 318 FAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSCYRGEGK-LSLPWLLNKELG----C 372
FA G + ++ALC F + + +++ + CY G+ S E G C
Sbjct: 303 FAAGPRGT-----QAALCAFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRC 357
Query: 373 INSPLQIDDDF-CGQDFN-QPLGGTVTIEGTPLFVDKDDGLTAVAAYDYRGRTVVFAGTR 430
+ PL + + CG + P+ G +E PL + ++AVAA G + F G
Sbjct: 358 VTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPL-LKLGQPVSAVAALQADGHMIAFLGDT 416
Query: 431 SGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVE 490
G++ K+ + G + + + V GS I DL+L + +LY +T QV R+PV
Sbjct: 417 QGQLYKVFLH----GSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVA 472
Query: 491 SCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRFAADLLQ---C--VQLTV 545
+C Q+ C CL ++DP CGWCVL C+R+ C RA + ++ + C +Q +
Sbjct: 473 ACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLL 532
Query: 546 QPRNVSVTMSQVPLVLQAWNVPDLSAGVNCSFEDFTESESVLEDGRIHCRSPSAREVAPI 605
+ QV L + + D +C+F D+ +S + +E + C +P +V P+
Sbjct: 533 PGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDY-DSLAHVEGPHVACVTPPQDQV-PL 590
Query: 606 TRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCSVHQS------CLSCVNGSFPCHWCKY 659
D V L L ++ A+ +F FY+CS Q+ C +CV + CHWC
Sbjct: 591 NPPGTDHVTVPLALMFEDV--TVAATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQ 648
Query: 660 RHVCTHN---------VADCAFLEGRVNVSEDCPQI--LPSTQIYVPVGVVKPITLAARN 708
C + + ++ +V CPQ+ L + VPVG + L RN
Sbjct: 649 SSHCVYGEHCPEGERTIYSAQEVDIQVRGPGACPQVEGLAGPHL-VPVGWESHLALRVRN 707
Query: 709 LPQPQSGQRGYECLFHIPGS----PARVTALRFNSSSLQCQNSSYSYEGNDVSDLPVNLS 764
L + + C +PG PA + +S + CQ + Y +LPV +
Sbjct: 708 LQHFRGLPASFHCWLELPGELRGLPATLEETAGDSGLIHCQAHQF-YPSMSQRELPVPIY 766
Query: 765 VVWNGNFVIDNPQNIQAHLYKCPALRESCGLCLKADPRFECGWCVAERRCSLRHHCAADT 824
V +DN + LY C C C A+ C WC A+ + + R+
Sbjct: 767 VTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAANRSLGCLWC-ADGQPACRYGPLCPP 825
Query: 825 PASWMHARHGSSRCTDPKILKLSPETGPRQGGTRLTITGENLGLRFEDVRLGVRVGKVLC 884
A + C P I + P TGP +GG LTI G NLG F DV+ V V C
Sbjct: 826 GAVEL-------LCPAPSIDAVEPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPC 878
Query: 885 SPVESEYISAEQIVCEIGDASSVRAHDALVEVCVRDCSPHYRALSPKRFTFVTPTFYRVS 944
+P S Y ++ +IVC A + V V ++ P +S + FT+ P +S
Sbjct: 879 NPEPSLYRTSARIVCVTSPAPN--GTTGPVRVAIKSQPP---GISSQHFTYQDPVLLSLS 933
Query: 945 PSRGPLSGGTWIGIEGSHLNAGSDVAVSVGGRPCSFSWRNSRE-IRCLTPPGQSPGSAPI 1003
P GP +GGT + I G HL G + + VGG+PC E I C T P +PG A +
Sbjct: 934 PRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCPEAIVCRTRPQAAPGEAAV 993
Query: 1004 IININRAQLTNPEVKYNYTEDPTILRIDPEWSINSGGTLLTVTGTNLATVREPRIRA--- 1060
++ AQ T + YT +P ++ +P S GG L+ V GT L V+ P +
Sbjct: 994 LVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRVRGTGLDVVQRPLLSVWLE 1053
Query: 1061 --------------------------------KYGG--IERENGCLVYNDTTMVCRAPSV 1086
+ GG ++ C V + + ++CR+P+V
Sbjct: 1054 ADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCSTVCSVNSSSLLLCRSPAV 1113
Query: 1087 ANPVRSPPELGERPDELGFVMDNVRSLLVLNS--TSFLYYPDPVLEPLS---PTGLLELK 1141
P R+ P+ + F +DNV+ S FLY P+P L PLS P LK
Sbjct: 1114 --PDRAHPQ------RVFFTLDNVQVDFASASGGQGFLYQPNPRLAPLSREGPARPYRLK 1165
Query: 1142 PSSPLILKGRNLLPPAPGNSRLNYTVLIGSTPCTL-TVSETQLLCEAP-------NLTGQ 1193
P L ++G L G S+ V IG C + T++ T L CE P N +G
Sbjct: 1166 PGHVLDVEGEGL---NLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHAPQPANGSGL 1222
Query: 1194 HKVTVRAGGFEFSPGTLQVYSD---SLLTLPAIVGIGGGGGLLLLVIVAVLIAYKRKSRD 1250
+ V+ G + + G +Q ++ S + A G+G G +L+ ++ + + Y+ KS+
Sbjct: 1223 PQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLTLMYRHKSKQ 1282
Query: 1251 ADRTLKRLQLQMDNLESRVALECKEAFAELQTDIHELTNDLDGAGIPFLDYRTYAMRVLF 1310
A R +++ +Q+++LE+ V +C++ F +L T++ +L++DL+G+GIPFLDYRTYA R F
Sbjct: 1283 ALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDYRTYAERAFF 1342
Query: 1311 PGIEDHPVLKEMEVQ------ANVEKSLTLFGQLLTKKHFLLTFIRTLEAQRSFSMRDRG 1364
PG P+ + E A V + LT LL K FLLT I TLE Q SFS RDR
Sbjct: 1343 PGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRC 1402
Query: 1365 NVASLIMTALQGEMEYATGVLKQLLSDLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTF 1424
+VASL+ AL G++EY T +++ LL DL + +PKL+LRRTE++ EK+LTNW +
Sbjct: 1403 HVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVH--RNPKLMLRRTETMVEKLLTNWLSI 1460
Query: 1425 LLYKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLNC 1484
LY FL+E AGEPL+ML+ AI+ Q++KGP+DA+TG+A+ +L++ +L+R+ ++++ LTL
Sbjct: 1461 CLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQPLTLMV 1520
Query: 1485 -VNPENENAP------EVPVKGLDCDTVTQAKEKLLDAAYKGVPYSQRPKAADMDLEWRQ 1537
V P A VP + LD DT+TQ KEK+LD YKG P+SQRP +DLEWR
Sbjct: 1521 LVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYKGTPFSQRPSVHALDLEWRS 1580
Query: 1538 GRMARIILQDEDVTTKIDNDWKRLNTLAHYQVTDGSSVALVPKQTSAYNISNSSTFTKSL 1597
G + L DED+T+ N WKRLNTL HY+V DG++V LVP+ + ST ++SL
Sbjct: 1581 GLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQ------LHRGSTISQSL 1634
Query: 1598 SRYESMLRTASSPDSLRSRTPMITPDLESGTKLWHLVKNHDH----------LDQREGDR 1647
++ L P + E G LWHLVK + L +RE R
Sbjct: 1635 AQR----------CPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPAR 1684
Query: 1648 GSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHQ 1707
+K + EIYLTRLL+ KGTLQKFVDD F+ I S +P+A+KY+FD LDE A+KH
Sbjct: 1685 -AKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSV---NRPIPIAVKYLFDLLDELAEKHG 1740
Query: 1708 IHDADVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHK 1767
I D H WK+N L LRFWVN +KNPQ +FD+ + DA L+V+AQTF+DSC+TSEHK
Sbjct: 1741 IEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHK 1800
Query: 1768 LGKDSPSNKLLYAKDIPNYKSWVERYYADIAKMPAISDQDMSAYLAEQSRLHLSQFNSMS 1827
+G+DSP NKLLYA++IP YK VERYYADI + S Q+M++ LAE S + S + +
Sbjct: 1801 VGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLE 1860
Query: 1828 ALHEIYSYITKYKDEILAALEKDEQARRQRLRSKLEQV 1865
AL E+Y++I +Y D+I++ALE+D ++ +L +L+QV
Sbjct: 1861 ALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQV 1898
>gi|149363636 plexin B2 [Homo sapiens]
Length = 1838
Score = 932 bits (2410), Expect = 0.0
Identities = 644/1948 (33%), Positives = 989/1948 (50%), Gaps = 208/1948 (10%)
Query: 1 MWAEA--GLPRAGGGSQPPFRTFSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLL 58
+WA GL AG +P F S+ L HL V E +G VY+GAVN +Y+L L L
Sbjct: 5 LWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAKLQLE 64
Query: 59 RAHVTGPVEDNEKCYPPPSVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFL 118
+ TGP DN+KC PP C H TDNVN+LLLLD RL+ CGS +GIC
Sbjct: 65 QQVATGPALDNKKCTPPIEASQC-HEAEMTDNVNQLLLLDPPRKRLVECGSLFKGICALR 123
Query: 119 RLDD--LFKLGEPHHRKEHYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGT---PIDGKSE 173
L + L E ++ +++S E + G++ + PG G LFVG P D
Sbjct: 124 ALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPG-GDRVLFVGKGNGPHDNG-- 180
Query: 174 YFPTLSSRRLMANEEDADMFGFVYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFV 233
+ S RL+ + + F Y D + ++T +V +F +V
Sbjct: 181 ---IIVSTRLLDRTDSREAFE-AYTDHATYKAGYLSTNTQQ--------FVAAFEDGPYV 228
Query: 234 YYLTLQLDTQLTSPDAAGEHFFTSKIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAY 293
+++ Q D + + R+C +DP +YSY+E + C D +
Sbjct: 229 FFVFNQQDKHPARN--------RTLLARMCREDPNYYSYLEMDLQCRDP--------DIH 272
Query: 294 LSRPGRALAHQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSC 353
+ G LA + VL+ VF++ ++ P + LCLF L + K++ +C
Sbjct: 273 AAAFGTCLAASVAAPGSGRVLYAVFSRDSRSSGGPG--AGLCLFPLDKVHAKMEANRNAC 330
Query: 354 YRG--EGKLSLPWLLNKELGCINSPLQIDDDF-CGQD-FNQPLGGTVTIEGTPLFVDKDD 409
Y G E + + ++ C F CG + PLG + GT +
Sbjct: 331 YTGTREARDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGL 390
Query: 410 GLTAVAAYDYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDLVL 469
LTAV TV F GT GRI K+ + P G + Y+S++ + + RDLVL
Sbjct: 391 NLTAVTVAAENNHTVAFLGTSDGRILKVYL---TPDGTSS-EYDSILVEINKRVKRDLVL 446
Query: 470 SPNHQYLYAMTEKQVTRVPVESCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADE 529
S + LYAMT+ +V R+PV+ C+ Y +C C S+DP+CGWCV+ C+R+ C RA+E
Sbjct: 447 SGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAEE 506
Query: 530 PQRFA-ADLLQCVQLT-VQPRNVSVTMSQVPLVLQAWNVPDLSAG--VNCSFEDFTESES 585
+ + CV +T QP+N+S +Q + L +P LS + C F + +
Sbjct: 507 ASHWLWSRSKSCVAVTSAQPQNMS-RRAQGEVQLTVSPLPALSEEDELLCLFGESPPHPA 565
Query: 586 VLEDGRIHCRSPSAREVAPITRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCSVHQS-- 643
+E + C SPS+ P+T D V + L + S + FY+C S
Sbjct: 566 RVEGEAVICNSPSS---IPVTPPGQDHVAVTIQLLLRRGNIFLTSYQYPFYDCRQAMSLE 622
Query: 644 ----CLSCVNGSFPCHWCKYRHVCTHNVADCAFLEGRVNVSEDCPQILPSTQIYVPVGVV 699
C+SCV+ + C W H C + R ++ + CPQ L + + +P+
Sbjct: 623 ENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRAHMEDSCPQFLGPSPLVIPMNHE 682
Query: 700 KPITLAARNLPQPQSGQR--GYECL-FHIPGSPARVTALRFNSSSLQCQNSSYSYEGNDV 756
+ +NL + G + L F P + F + L S++ N+
Sbjct: 683 TDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGTFAFRTPKL-------SHDANET 735
Query: 757 SDLPVNLSVVWNGNFVIDNPQNIQAHLYKCPALRESCGLCLKADPRFECGWCVAERRCSL 816
LP++L V G + + LY C R C LC A+P + C WC + RC
Sbjct: 736 --LPLHLYVKSYGKNI---DSKLHVTLYNCSFGRSDCSLCRAANPDYRCAWCGGQSRCVY 790
Query: 817 RHHCAADTPASWMHARHGSSRCTDPKILKLSPETGPRQGGTRLTITGENLGLRFEDVRLG 876
C + +S C P I ++ PETGP GG R+TI G NLG++ D++
Sbjct: 791 EALC------------NTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQR- 837
Query: 877 VRVGKVLCSPVESEYISAEQIVCEIGDASSVRAHDALVEVCVRDCSPHYRALSPKRFTFV 936
+ V CS Y + +IVC I A + V+V + R+ +FTF
Sbjct: 838 ISVAGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGK----LGRSPPNVQFTFQ 893
Query: 937 TPTFYRVSPSRGPLSGGTWIGIEGSHLNAGS--DVAVSVGGRPCSFSWRNSREIRCLTPP 994
P V P +GP +GGT + I G+HL+ GS DV V++ G PC + + +++C+T P
Sbjct: 894 QPKPLSVEPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVT-KFGAQLQCVTGP 952
Query: 995 GQSPGSAPIIININRAQLTNPEVKYNYTEDPTILRIDPEWSINSGGTLLTVTGTNLATVR 1054
+ G + ++ + + NP + + Y E+P + +P S SGG + VTG + ++
Sbjct: 953 QATRGQMLLEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQ 1012
Query: 1055 --------EPRIRAKYGGIEREN---------GCLVYNDTTMVCRAPSVANPVRSPPELG 1097
EP +++ E E+ + +NDT +V +P+V
Sbjct: 1013 RFAMVVIAEP-LQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVP---------- 1061
Query: 1098 ERPDELGFV----MDNVRSLLVLNSTSFLYYPDPVLEPLSPTGLLELKPSSPLILKGRNL 1153
E P+ MD R+LL + +F Y PDP E TG ++ + + + +G NL
Sbjct: 1062 EEPEAYNLTVLIEMDGHRALLRTEAGAFEYVPDPTFENF--TGGVKKQVNKLIHARGTNL 1119
Query: 1154 LPPAPGNSRLNYTVLIGSTPCTL-TVSETQLLCEAPNLTGQHK-------------VTVR 1199
+ +G+ CT+ T++ET L CE P + K V+
Sbjct: 1120 ---NKAMTLQEAEAFVGAERCTMKTLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVK 1176
Query: 1200 AGGFEFSPGTLQV---YSDSLLTL--PAIVGIGGGGGLLLLVIVAVLI-AYKRKSRDADR 1253
G E+ G ++ SD L+L P ++ + ++V++AV + Y RKS+ A+R
Sbjct: 1177 FGSREWVLGRVEYDTRVSDVPLSLILPLVI-------VPMVVVIAVSVYCYWRKSQQAER 1229
Query: 1254 TLKRLQLQMDNLESRVALECKEAFAELQTDIHELTNDLDGAGIPFLDYRTYAMRVLF--- 1310
++++ Q++ LE V CK+ F +L ++ + TND+ AGIP LDY+TY RV F
Sbjct: 1230 EYEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDYKTYTDRVFFLPS 1289
Query: 1311 -PGIEDHPVLKEMEV----QANVEKSLTLFGQLLTKKHFLLTFIRTLEAQRSFSMRDRGN 1365
G +D + ++++ + VE++L F LL K FL+ FI TLE QR FS R +
Sbjct: 1290 KDGDKDVMITGKLDIPEPRRPVVEQALYQFSNLLNSKSFLINFIHTLENQREFSARAKVY 1349
Query: 1366 VASLIMTALQGEMEYATGVLKQLLSDLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFL 1425
ASL+ AL G++EY T ++ L +L+E+ + +KN PKL+LRR+E+V E+ML+NW +
Sbjct: 1350 FASLLTVALHGKLEYYTDIMHTLFLELLEQYVVAKN-PKLMLRRSETVVERMLSNWMSIC 1408
Query: 1426 LYKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLNCV 1485
LY++LK+ AGEPL+ L+ AIK Q+EKGP+DA+ +A+Y+L++ L+ ++Y LT++ +
Sbjct: 1409 LYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEYAPLTVSVI 1468
Query: 1486 NPENENAPEVPVKGLDCDTVTQAKEKLLDAAYKGVPYSQRPKAADMDLEWRQGRMARIIL 1545
++E +PVK L+CDT++Q KEK++D Y+G P S P+ + LEWR G A+I L
Sbjct: 1469 -VQDEGVDAIPVKVLNCDTISQVKEKIIDQVYRGQPCSCWPRPDSVVLEWRPGSTAQI-L 1526
Query: 1546 QDEDVTTKIDNDWKRLNTLAHYQVTDGSSVALVPKQTSAYNISNSSTFTKSLSRYESMLR 1605
D D+T++ + WKR+NTL HY V DG+++ L S +
Sbjct: 1527 SDLDLTSQREGRWKRVNTLMHYNVRDGATLIL------------------------SKVG 1562
Query: 1606 TASSPDSLRSRTPMITPDL-ESGTKLWHLVKNHDHLDQREGDRGS-------KMVSEIYL 1657
+ P+ + P L E ++WHLV+ D +D+ + RGS K ++EIYL
Sbjct: 1563 VSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEIYL 1622
Query: 1658 TRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHQIHDADVRHTW 1717
TRLL+ KGTLQ+FVD+ F+++ + H A+P A+KY FDFLDEQA+KH I D D H W
Sbjct: 1623 TRLLSVKGTLQQFVDNFFQSVLAPGH---AVPPAVKYFFDFLDEQAEKHNIQDEDTIHIW 1679
Query: 1718 KSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHKLGKDSPSNKL 1777
K+N LPLRFWVN++KNP F+FD+H + + DA LSV+AQTFMD+C+ +EHKL +DSPSNKL
Sbjct: 1680 KTNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKL 1739
Query: 1778 LYAKDIPNYKSWVERYYADIAKMPAISDQDMSAYLAEQSRLHLSQFNSMSALHEIYSYIT 1837
LYAK+I YK VE YY I +M +SDQDM+ +LAE SR H N++ ALH++Y Y
Sbjct: 1740 LYAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQ 1799
Query: 1838 KYKDEILAALEKDEQARRQRLRSKLEQV 1865
KY DEI+ ALE+D A++ +L +L+Q+
Sbjct: 1800 KYYDEIINALEEDPAAQKMQLAFRLQQI 1827
>gi|157694524 plexin D1 [Homo sapiens]
Length = 1925
Score = 861 bits (2225), Expect = 0.0
Identities = 629/1946 (32%), Positives = 944/1946 (48%), Gaps = 214/1946 (10%)
Query: 38 GEVYVGAVNRIYKLSG-NLTLLRAHVTGPVEDNEKCYPPPSVQ-SCPHGLGSTDNVNKLL 95
G VY+ AVNR+Y+LSG NL+L GPV D+ C+ P Q SC H TDN NK+L
Sbjct: 69 GTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRRLTDNYNKIL 128
Query: 96 LLDYAANRLLACGSASQGICQFLRLDDLFKLG-------EPHHRKEHYLSSVQEAG---- 144
LD ++ CGS QG CQ R ++ + P + S + A
Sbjct: 129 QLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSMLNVAANHPN 188
Query: 145 -SMAGVLIAGPPGQGQAKLFVGTPIDGKSEYF---------------PTLSSRRLMANEE 188
S G+++ G G ++L VG G F P ++ R L +
Sbjct: 189 ASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRNRSLEDHRFENTPEIAIRSLDTRGD 248
Query: 189 DADMFGF-VYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSP 247
A +F F + + ++K + K + S Y L L+++ +
Sbjct: 249 LAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSAFLHPSDPPPGAQSYAYLALNSEARAG 308
Query: 248 DAAGEHFFTSKIVRLCVD-----DPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALA 302
D + S + R+C+ D K + +G + AG R G +
Sbjct: 309 DKESQA--RSLLARICLPHGAGGDAKKLTESYIQLGLQCAGGAGR----------GDLYS 356
Query: 303 HQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSCYRGEGKLSL 362
+ + + LF VF + Q + +ALC F ++ I+ +C+ +
Sbjct: 357 RLVSVFPARERLFAVFERPQGSPAARAAPAALCAFRFADVRAAIRAARTACFVEPAPDVV 416
Query: 363 PWLLNKELGC-------INSPLQIDDDFCGQDFNQ-PLGGTVTIEGTPLFVDKDDGLTAV 414
L + G +N LQ + CG Q PL ++ TP+F + GLT+V
Sbjct: 417 AVLDSVVQGTGPACERKLNIQLQPEQLDCGAAHLQHPLSILQPLKATPVF--RAPGLTSV 474
Query: 415 AAYDYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDLVLSP-NH 473
A T VF GT +GR+ KI ++ S ++ V G P+ + P +
Sbjct: 475 AVASVNNYTAVFLGTVNGRLLKINLNES----MQVVSRRVVTVAYGEPVHHVMQFDPADS 530
Query: 474 QYLYAMTEKQVTRVPVESCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRF 533
YLY MT Q+ RV V +C +++C C+G+ D +CGWC L + C+ + C + + Q F
Sbjct: 531 GYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDCTNSSQ-QHF 589
Query: 534 AADLLQ----CVQLTVQPRNVSVTMSQVPLVLQ-AWNVPDLSA-GVNCSFEDFTESESVL 587
+ C +TV P + V ++LQ + ++P LS + C + + + + +
Sbjct: 590 WTSASEGPSRCPAMTVLPSEIDVRQEYPGMILQISGSLPSLSGMEMACDYGNNIRTVARV 649
Query: 588 EDGRI-----HCRSPSAREVAPITRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCS--- 639
+C + P Q V + + + G+ +F Y+CS
Sbjct: 650 PGPAFGHQIAYCNLLPRDQFPPFPPNQDH---VTVEMSVRVNGRNIVKANFTIYDCSRTA 706
Query: 640 ---VHQSCLSCVNGSFPCHWCKYRHVCTHNVADCAFLEGRVNVSEDCPQILPSTQIYVPV 696
H +C SC++ +PC WC +H C N + C + +DCP+ L S VP
Sbjct: 707 QVYPHTACTSCLSAQWPCFWCSQQHSCVSNQSRCEASPNPTS-PQDCPRTLLSPLAPVPT 765
Query: 697 GVVKPITLAARNLPQPQSGQRGYECLFHIPGSPARVTALRFNSSSLQCQNSSYSYEGNDV 756
G + I + N Q EC F G A+ N S ++C + +
Sbjct: 766 GGSQNILVPLANTAFFQGA--ALECSF---GLEEIFEAVWVNESVVRC-DQVVLHTTRKS 819
Query: 757 SDLPVNLSVVWNGNFVIDNPQNIQAHLYKCPALRESCGLCL-KADPRFECGWCVAERRCS 815
P++L + +D+P+ + +Y C C CL + D C W C
Sbjct: 820 QVFPLSLQLKGRPARFLDSPEPMTVMVYNCAMGSPDCSQCLGREDLGHLCMWSDG---CR 876
Query: 816 LRHHCAADTPASWMHARHGSSRCTDPKILKLSPETGPRQGGTRLTITGENLGLRFEDVRL 875
LR P M + C P+I + P +GP GGT LTI G NLG R DV
Sbjct: 877 LRG------PLQPM-----AGTCPAPEIRAIEPLSGPLDGGTLLTIRGRNLGRRLSDVAH 925
Query: 876 GVRVGKVLCSPVESEYISAEQIVCEIGDA----SSVRAHDALVEVCVRDCSPHYRALSPK 931
GV +G V C P+ Y +E+IVC G A S V +A E RD
Sbjct: 926 GVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPLSGVVTVNASKEGKSRD----------- 974
Query: 932 RFTFVTPTFYRVSPSRGPLSGGTWIGIEGSHLNAGSDVAVSVGGR-PCSFSWRNSREIRC 990
RF++V P + + P+ GP +GGT I I G+ L+ GS++ V V PC+ R I C
Sbjct: 975 RFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTELMRTDTSIAC 1034
Query: 991 LTPPGQSPGSAPIIININRAQLTNPEVKYNYTEDPTILRIDPEWSINSGGTLLTVTGTNL 1050
P G P P+ + R + + + Y ++P I I P S SGG +TV G
Sbjct: 1035 TMPEGALPAPVPVCVRFERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGRTITVAGERF 1094
Query: 1051 ATVREPRIRAKYGGIERENGCLVYNDTTMVCRAPSVANPVRSPPEL----GERPDELGFV 1106
V+ + + G E C V N T + C +P + +P + DE+
Sbjct: 1095 HMVQNVSMAVHHIGRE-PTLCKVLNSTLITCPSPGALSNASAPVDFFINGRAYADEVAVA 1153
Query: 1107 MDNVRSLLVLNSTSFL--YYPDPVLEPLSPTGLLELKPSSPLIL---KGRNLLPPAPGNS 1161
+ + + F Y P+P ++ P PL L K ++ L G
Sbjct: 1154 EELLDPEEAQRGSRFRLDYLPNPQFSTAKREKWIKHHPGEPLTLVIHKEQDSL----GLQ 1209
Query: 1162 RLNYTVLIGSTPCTLTVSETQLLCEAPN-----LTGQHKVTVRAGGFEFSPGTLQVYSDS 1216
Y V IG C + + +++ + N GQ +T++ G F + TLQ+
Sbjct: 1210 SHEYRVKIGQVSCDIQIVSDRIIHCSVNESLGAAVGQLPITIQVGNFNQTIATLQLGGSE 1269
Query: 1217 LLTLPAIVGIGGGGGLLLLVIVAVLIAYKRKSRDADRTLKRLQLQMDNLESRVALECKEA 1276
+ +IV +LLL+ V L + KSR A+R ++ LQM+ +ES++ E ++
Sbjct: 1270 TAIIVSIVICS----VLLLLSVVALFVFCTKSRRAERYWQKTLLQMEEMESQIREEIRKG 1325
Query: 1277 FAELQTDIHELTNDLDGA-GIPFLDYRTYAMRVLFPGI---------------------- 1313
FAELQTD+ +LT +L+ + GIPFL+Y+ + R FP
Sbjct: 1326 FAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNSQGSSQ 1385
Query: 1314 --EDHPVLKEMEV----QANVEKSLTLFGQLLTKKHFLLTFIRTLEAQRSFSMRDRGNVA 1367
E HP+L E ++ + N+E+ ++LF LL KHFL+ F+ LE Q+ F++RDR ++A
Sbjct: 1386 AQETHPLLGEWKIPESCRPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRDRCSLA 1445
Query: 1368 SLIMTALQGEMEYATGVLKQLLSDLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLY 1427
SL+ AL G++EY T ++K+LL DLI+ + + +PKL+LRRTESV EKMLTNW + +Y
Sbjct: 1446 SLLTIALHGKLEYYTSIMKELLVDLIDAS--AAKNPKLMLRRTESVVEKMLTNWMSICMY 1503
Query: 1428 KFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLNCVNP 1487
L+E GEP F+L CAIKQQ+ KG IDAITG+ARY+L+E+ L+R+ I+ K LN V+
Sbjct: 1504 SCLRETVGEPFFLLLCAIKQQINKGSIDAITGKARYTLNEEWLLRENIEAKPRNLN-VSF 1562
Query: 1488 ENENAPEVPVKGLDCDTVTQAKEKLLDAAYKGVPYSQRPKAADMDLEWRQGRMARIILQD 1547
+ + V+ +D DT+TQ KEK+L+A K VPYSQ P+A D+DLEW IL+D
Sbjct: 1563 QGCGMDSLSVRAMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSYILRD 1622
Query: 1548 EDVTTKIDNDWKRLNTLAHYQVTDGSSVALVPKQTSAYNISNSSTFTKSLSRYESMLRTA 1607
D T+ +++ K+LNTLAHY++ +G+S+A+ + + ++ L
Sbjct: 1623 LDDTSVVEDGRKKLNTLAHYKIPEGASLAM-----------------SLIDKKDNTLGRV 1665
Query: 1608 SSPDSLRSRTPMITPDLESGTKLWHLVKNHDHL-DQREGDRGS---KMVSEIYLTRLLAT 1663
D+ K +HLV D L + ++ R S K++ EIYLTRLL+T
Sbjct: 1666 KDLDT---------------EKYFHLVLPTDELAEPKKSHRQSHRKKVLPEIYLTRLLST 1710
Query: 1664 KGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHQIHDADVRHTWKSNCLP 1723
KGTLQKF+DDLF+ I S R PLA+KY FDFL+EQA+K I D D H WK+N LP
Sbjct: 1711 KGTLQKFLDDLFKAILSI--REDKPPLAVKYFFDFLEEQAEKRGISDPDTLHIWKTNSLP 1768
Query: 1724 LRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHKLGKDSPSNKLLYAKDI 1783
LRFWVN++KNPQFVFDI K DACLSV+AQ F+D+CS S+ +LGKDSP+NKLLYAK+I
Sbjct: 1769 LRFWVNILKNPQFVFDIDKTDHIDACLSVIAQAFIDACSISDLQLGKDSPTNKLLYAKEI 1828
Query: 1784 PNYKSWVERYYADIAKMPAISDQDMSAYLAEQSRLHLSQFNSMSALHEIYSYITKYKDEI 1843
P Y+ V+RYY I M +S+Q+M+A+LAE+SR + ++FN+ A+ EIY Y +Y+ +I
Sbjct: 1829 PEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEIYKYAKRYRPQI 1888
Query: 1844 LAALEKDEQARRQRLRSKLEQVVDTM 1869
+AALE + ARR +L+ K EQVV M
Sbjct: 1889 MAALEANPTARRTQLQHKFEQVVALM 1914
>gi|194272180 plexin B1 [Homo sapiens]
Length = 2135
Score = 813 bits (2100), Expect = 0.0
Identities = 501/1248 (40%), Positives = 685/1248 (54%), Gaps = 124/1248 (9%)
Query: 694 VPVGVVKPITLAARNLPQPQSGQRGYECLFHIPGSPARVTAL------RFNSSSLQCQNS 747
+PV V + I L RNL Q G EC+ + G V A + CQ
Sbjct: 925 MPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEVVVEARVECEPPPDTQCHVTCQQH 984
Query: 748 SYSYEGNDVSDLPVNLSVVWNGNFVIDNPQNIQAHLYKCPALRESCGLCLKADPRFECGW 807
SYE +L V L + G +D+ + + LY C C C A P++ C W
Sbjct: 985 QLSYEALQ-PELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSRCQTAMPQYGCVW 1043
Query: 808 CVAER-RCSLRHHCAADTPASWMHARHGSSRCTDPKILKLSPETGPRQGGTRLTITGENL 866
C ER RC R C A +++C P I + P TGP GGTR+TI G NL
Sbjct: 1044 CEGERPRCVTREACG--------EAEAVATQCPAPLIHSVEPLTGPVDGGTRVTIRGSNL 1095
Query: 867 GLRFEDVRLGVRVGKVLCSPVESEYISAEQIVCEIGDASSVRAHDALVEVCVRDCSPHYR 926
G +DV V V V C+ EY + +VC G + A VEV R R
Sbjct: 1096 GQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEVPGRG-----R 1150
Query: 927 ALSPKRFTFVTPTFYRVSPSRGPLSGGTWIGIEGSHLNAG--SDVAVSVGGRPCSF-SWR 983
+S F + P + + P+RGP +GGT + + GS L G D+ V VG +PC +
Sbjct: 1151 GVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQPCHLLPEQ 1210
Query: 984 NSREIRCLTPPGQSPGSAPIIININRAQLTNPEVKYNYTEDPTILRIDPEWSINSGGTLL 1043
S ++RC T P +P + P+ + + ++ YT DP I P S SGG +
Sbjct: 1211 QSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTKSFLSGGREI 1270
Query: 1044 TVTGTNLATVREPRIRAKY--------GGIER---------------------ENGCLVY 1074
V G NL V+ PRIR G+ R E C V
Sbjct: 1271 CVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSSQQFEEPCHVN 1330
Query: 1075 NDTTMVCRAPSVANPVRSPPELGERP-DELGFVMDN-VRSLLVLNSTSFLYYPDPVLEPL 1132
+ + CR P++ P L E P + F++DN V LN T F Y DP L+PL
Sbjct: 1331 SSQLITCRTPAL-------PGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTLQPL 1383
Query: 1133 SP---TGLLELKPSSPLILKGRNLLPPAPGNSRLNYTVLIGSTPCTL-TVSETQLLCEAP 1188
+P T KP S ++G NL S+ +IG PC + T++ L CE P
Sbjct: 1384 NPEDPTMPFRHKPGSVFSVEGENL---DLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1440
Query: 1189 ---NLTGQHKV----------TVRAGGFEFSPGTLQVYSDSLLTLP--AIVGIGGGGGLL 1233
L H + TV+ G FS G +Q +S P A VG+G G LL
Sbjct: 1441 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1500
Query: 1234 LLVIVAVLIAYKRKSRDADRTLKRLQLQMDNLESRVALECKEAFAELQTDIHELTNDLDG 1293
L ++ +++ Y+RKS+ A R K++Q+Q++NLES V CK+ F +L T++ +LT+DL G
Sbjct: 1501 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1560
Query: 1294 AGIPFLDYRTYAMRVLFPGIEDHPVLKEMEV----QANVEKSLTLFGQLLTKKHFLLTFI 1349
+GIPFLDY+ YA R+ FPG + P+ +++ V + VE+ L LL K FL FI
Sbjct: 1561 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1620
Query: 1350 RTLEAQRSFSMRDRGNVASLIMTALQGEMEYATGVLKQLLSDLIEKNLESKNHPKLLLRR 1409
TLE+QR+FS RDR VASL+ AL G++EY T +L+ LLSDL+ + + +KN PKL+LRR
Sbjct: 1621 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYV-AKN-PKLMLRR 1678
Query: 1410 TESVAEKMLTNWFTFLLYKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDK 1469
TE+V EK+LTNW + LY F+++ GEPL+ML+ IK Q++KGP+D++TG+A+Y+L++++
Sbjct: 1679 TETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNR 1738
Query: 1470 LIRQQIDYKTLTLNC---VNPENENAPEVPVKGLDCDTVTQAKEKLLDAAYKGVPYSQRP 1526
L+R+ ++Y+ LTLN V P A VPVK LDCDT++QAKEK+LD YKGVP +QRP
Sbjct: 1739 LLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRP 1798
Query: 1527 KAADMDLEWRQGRMARIILQDEDVTTKIDNDWKRLNTLAHYQVTDGSSVALVPKQTSAYN 1586
+D+EWR G +IL DEDVT+++ W+RLNTL HY+V DG++VALVP T
Sbjct: 1799 DPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVL 1858
Query: 1587 ISNSSTFTKSLSRYESMLRTASSPDSLRSRTPMITPDLESGTKLWHLVKNHDHLDQREGD 1646
N RTPM+ E G + WHLVK D +
Sbjct: 1859 RENQDYVPGE-------------------RTPMLEDVDEGGIRPWHLVKPSDEPEPPRPR 1899
Query: 1647 RGS---------KMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFD 1697
RGS K + EIYLTRLL+ KGTLQKFVDDLF+ I ST+ +PLA+KY FD
Sbjct: 1900 RGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSR---PVPLAVKYFFD 1956
Query: 1698 FLDEQADKHQIHDADVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTF 1757
LDEQA +H I D D H WK+N LPLRFW+N+IKNPQFVFD+ + DA L V+AQTF
Sbjct: 1957 LLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTF 2016
Query: 1758 MDSCSTSEHKLGKDSPSNKLLYAKDIPNYKSWVERYYADIAKMPAISDQDMSAYLAEQSR 1817
MD+C+ ++HKLG+DSP NKLLYA+DIP YK VERYYADI + SDQ+M++ LAE S
Sbjct: 2017 MDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSW 2076
Query: 1818 LHLSQFNSMSALHEIYSYITKYKDEILAALEKDEQARRQRLRSKLEQV 1865
+ + ALHE+Y YI KY D+I+ ALE+D A++ +L +L+Q+
Sbjct: 2077 NYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQI 2124
Score = 256 bits (653), Expect = 2e-67
Identities = 218/751 (29%), Positives = 332/751 (44%), Gaps = 86/751 (11%)
Query: 17 PFRTFSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPP 76
P F+ + L HL +G +Y+GA N +++LS L L TGPV D+ C PP
Sbjct: 24 PPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPV 83
Query: 77 SVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRK--E 134
CP T+N N+LLL+ A L+ CGS QG+C+ RL L +L R
Sbjct: 84 MPDECPQAQ-PTNNPNQLLLVSPGA--LVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDT 140
Query: 135 HYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSSRRLMANEEDADMFG 194
Y+++ A S G++ G G+ + G G P +++R L + A
Sbjct: 141 QYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALWPPDPQA---A 197
Query: 195 FVYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHF 254
F Y++ K+ LS++ ++V +F Y+L L+ D Q S
Sbjct: 198 FSYEET-----AKLAVGRLSEYSH---HFVSAFARGASAYFLFLRRDLQAQS------RA 243
Query: 255 FTSKIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVL 314
F + + R+C+ D +YSYVE P+ CE G Y L+Q A ++ R +AH +VL
Sbjct: 244 FRAYVSRVCLRDQHYYSYVELPLACE--GGRYGLIQAAAVAT-SREVAHG-------EVL 293
Query: 315 FTVFAQGQKNRV-KPPKE-------SALCLFTLRAIKEKIKERIQSCYRGEGKLS----- 361
F F+ V +PP SALC F L + +CY EG+
Sbjct: 294 FAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEV 353
Query: 362 --LPWLLNKELGCINSPLQIDDDF-CGQDFN-QPLGGTVTIEGTPLFVDKDDGLTAVAAY 417
+ + +N + C P+ D + CG D P+ V +E TP+ LTAVA
Sbjct: 354 AYIEYDVNSD--CAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVT 411
Query: 418 DYRGRTVVFAGTRSGRIRKILVDLSNPG--GRPALAYESVVAQEGSPILRDLVLSPNHQY 475
G T+ F G G++ ++ + PG G P Y + Q+GS + RDL ++
Sbjct: 412 MEDGHTIAFLGDSQGQLHRVYL---GPGSDGHP---YSTQSIQQGSAVSRDLTFDGTFEH 465
Query: 476 LYAMTEKQVTRVPVESCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRFAA 535
LY MT+ + +VPV SC Q+ C CL RDP+CGWCVL CSRR C R P+++
Sbjct: 466 LYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLW 525
Query: 536 DL---LQCVQL-TVQPRNVSVTMSQVPLVLQAWNVPDLSAG--VNCSFEDFTESESVLED 589
L C+Q+ + P N+S ++ + L ++P L G +C F + +S ++L
Sbjct: 526 SFQPELGCLQVAAMSPANISREETR-EVFLSVPDLPPLWPGESYSCHFGEH-QSPALLTG 583
Query: 590 GRIHCRSPSAREVAPITRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCSV------HQS 643
+ C SP E + RG V + ++ + A FY+C
Sbjct: 584 SGVMCPSPDPSEAPVLPRGAD---YVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQ 640
Query: 644 CLSCVNGSFPCHWCKYRHVCTHNVADCAFLEGRVNVSEDCPQILPSTQIYVPVGVVKPIT 703
C +CV+ + C+WC ++H+CTH A C G + S P + P P
Sbjct: 641 CQACVSSRWGCNWCVWQHLCTHK-ASCD--AGPMVASHQSPLVSPDPPARGGPSPSPPTA 697
Query: 704 LAARNLPQPQSGQRGYECLFHIPGSPARVTA 734
A P P + L PG+P+ TA
Sbjct: 698 PKALATPAP-------DTLPVEPGAPSTATA 721
Score = 46.6 bits (109), Expect = 2e-04
Identities = 63/255 (24%), Positives = 94/255 (36%), Gaps = 36/255 (14%)
Query: 637 NCSVHQSCLSCVNGSFP-CHWCKYRHVCTHNVADCAFLEG------RVNVSEDCPQILPS 689
+C+ H C SC+ P C WC C+ ++C+ +G C Q+
Sbjct: 481 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRR-SECSRGQGPEQWLWSFQPELGCLQVAAM 539
Query: 690 TQIYVPVGVVKPITLAARNLPQPQSGQRGYECLFHIPGSPARVTALRFNSSSLQCQNSSY 749
+ + + + L+ +LP G+ Y C F SPA +T S +
Sbjct: 540 SPANISREETREVFLSVPDLPPLWPGE-SYSCHFGEHQSPALLTGSGVMCPSPDPSEAPV 598
Query: 750 SYEGNDVSDLPVNLSVVWNGNFVIDNPQNIQAHLYKCPALRE-----SCGLCLKADPRFE 804
G D + V L G VI Y C A+ E C C+ + R+
Sbjct: 599 LPRGADYVSVSVELRF---GAVVI---AKTSLSFYDCVAVTELRPSAQCQACVSS--RWG 650
Query: 805 CGWCVAERRCSLRHHCAADTPASWMH----------ARHGSSRC--TDPKILKL-SPETG 851
C WCV + C+ + C A P H AR G S T PK L +P+T
Sbjct: 651 CNWCVWQHLCTHKASCDAG-PMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTL 709
Query: 852 PRQGGTRLTITGENL 866
P + G T T ++
Sbjct: 710 PVEPGAPSTATASDI 724
Score = 33.5 bits (75), Expect = 2.0
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 10/81 (12%)
Query: 780 QAHLYKCP----ALRESCGLCLK-ADPRFECGWCVAERRCSLRHHCA-ADTPASWMHARH 833
Q+ L K P A C CL DP CGWCV RCS R C+ P W+ +
Sbjct: 471 QSTLLKVPVASCAQHLDCASCLAHRDPY--CGWCVLLGRCSRRSECSRGQGPEQWLWSFQ 528
Query: 834 GSSRCTDPKILKLSPETGPRQ 854
C ++ +SP R+
Sbjct: 529 PELGCL--QVAAMSPANISRE 547
>gi|40254442 plexin B1 [Homo sapiens]
Length = 2135
Score = 813 bits (2100), Expect = 0.0
Identities = 501/1248 (40%), Positives = 685/1248 (54%), Gaps = 124/1248 (9%)
Query: 694 VPVGVVKPITLAARNLPQPQSGQRGYECLFHIPGSPARVTAL------RFNSSSLQCQNS 747
+PV V + I L RNL Q G EC+ + G V A + CQ
Sbjct: 925 MPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEVVVEARVECEPPPDTQCHVTCQQH 984
Query: 748 SYSYEGNDVSDLPVNLSVVWNGNFVIDNPQNIQAHLYKCPALRESCGLCLKADPRFECGW 807
SYE +L V L + G +D+ + + LY C C C A P++ C W
Sbjct: 985 QLSYEALQ-PELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSRCQTAMPQYGCVW 1043
Query: 808 CVAER-RCSLRHHCAADTPASWMHARHGSSRCTDPKILKLSPETGPRQGGTRLTITGENL 866
C ER RC R C A +++C P I + P TGP GGTR+TI G NL
Sbjct: 1044 CEGERPRCVTREACG--------EAEAVATQCPAPLIHSVEPLTGPVDGGTRVTIRGSNL 1095
Query: 867 GLRFEDVRLGVRVGKVLCSPVESEYISAEQIVCEIGDASSVRAHDALVEVCVRDCSPHYR 926
G +DV V V V C+ EY + +VC G + A VEV R R
Sbjct: 1096 GQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEVPGRG-----R 1150
Query: 927 ALSPKRFTFVTPTFYRVSPSRGPLSGGTWIGIEGSHLNAG--SDVAVSVGGRPCSF-SWR 983
+S F + P + + P+RGP +GGT + + GS L G D+ V VG +PC +
Sbjct: 1151 GVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQPCHLLPEQ 1210
Query: 984 NSREIRCLTPPGQSPGSAPIIININRAQLTNPEVKYNYTEDPTILRIDPEWSINSGGTLL 1043
S ++RC T P +P + P+ + + ++ YT DP I P S SGG +
Sbjct: 1211 QSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTKSFLSGGREI 1270
Query: 1044 TVTGTNLATVREPRIRAKY--------GGIER---------------------ENGCLVY 1074
V G NL V+ PRIR G+ R E C V
Sbjct: 1271 CVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSSQQFEEPCHVN 1330
Query: 1075 NDTTMVCRAPSVANPVRSPPELGERP-DELGFVMDN-VRSLLVLNSTSFLYYPDPVLEPL 1132
+ + CR P++ P L E P + F++DN V LN T F Y DP L+PL
Sbjct: 1331 SSQLITCRTPAL-------PGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTLQPL 1383
Query: 1133 SP---TGLLELKPSSPLILKGRNLLPPAPGNSRLNYTVLIGSTPCTL-TVSETQLLCEAP 1188
+P T KP S ++G NL S+ +IG PC + T++ L CE P
Sbjct: 1384 NPEDPTMPFRHKPGSVFSVEGENL---DLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1440
Query: 1189 ---NLTGQHKV----------TVRAGGFEFSPGTLQVYSDSLLTLP--AIVGIGGGGGLL 1233
L H + TV+ G FS G +Q +S P A VG+G G LL
Sbjct: 1441 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1500
Query: 1234 LLVIVAVLIAYKRKSRDADRTLKRLQLQMDNLESRVALECKEAFAELQTDIHELTNDLDG 1293
L ++ +++ Y+RKS+ A R K++Q+Q++NLES V CK+ F +L T++ +LT+DL G
Sbjct: 1501 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1560
Query: 1294 AGIPFLDYRTYAMRVLFPGIEDHPVLKEMEV----QANVEKSLTLFGQLLTKKHFLLTFI 1349
+GIPFLDY+ YA R+ FPG + P+ +++ V + VE+ L LL K FL FI
Sbjct: 1561 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1620
Query: 1350 RTLEAQRSFSMRDRGNVASLIMTALQGEMEYATGVLKQLLSDLIEKNLESKNHPKLLLRR 1409
TLE+QR+FS RDR VASL+ AL G++EY T +L+ LLSDL+ + + +KN PKL+LRR
Sbjct: 1621 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYV-AKN-PKLMLRR 1678
Query: 1410 TESVAEKMLTNWFTFLLYKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDK 1469
TE+V EK+LTNW + LY F+++ GEPL+ML+ IK Q++KGP+D++TG+A+Y+L++++
Sbjct: 1679 TETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNR 1738
Query: 1470 LIRQQIDYKTLTLNC---VNPENENAPEVPVKGLDCDTVTQAKEKLLDAAYKGVPYSQRP 1526
L+R+ ++Y+ LTLN V P A VPVK LDCDT++QAKEK+LD YKGVP +QRP
Sbjct: 1739 LLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRP 1798
Query: 1527 KAADMDLEWRQGRMARIILQDEDVTTKIDNDWKRLNTLAHYQVTDGSSVALVPKQTSAYN 1586
+D+EWR G +IL DEDVT+++ W+RLNTL HY+V DG++VALVP T
Sbjct: 1799 DPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVL 1858
Query: 1587 ISNSSTFTKSLSRYESMLRTASSPDSLRSRTPMITPDLESGTKLWHLVKNHDHLDQREGD 1646
N RTPM+ E G + WHLVK D +
Sbjct: 1859 RENQDYVPGE-------------------RTPMLEDVDEGGIRPWHLVKPSDEPEPPRPR 1899
Query: 1647 RGS---------KMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFD 1697
RGS K + EIYLTRLL+ KGTLQKFVDDLF+ I ST+ +PLA+KY FD
Sbjct: 1900 RGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSR---PVPLAVKYFFD 1956
Query: 1698 FLDEQADKHQIHDADVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTF 1757
LDEQA +H I D D H WK+N LPLRFW+N+IKNPQFVFD+ + DA L V+AQTF
Sbjct: 1957 LLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTF 2016
Query: 1758 MDSCSTSEHKLGKDSPSNKLLYAKDIPNYKSWVERYYADIAKMPAISDQDMSAYLAEQSR 1817
MD+C+ ++HKLG+DSP NKLLYA+DIP YK VERYYADI + SDQ+M++ LAE S
Sbjct: 2017 MDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSW 2076
Query: 1818 LHLSQFNSMSALHEIYSYITKYKDEILAALEKDEQARRQRLRSKLEQV 1865
+ + ALHE+Y YI KY D+I+ ALE+D A++ +L +L+Q+
Sbjct: 2077 NYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQI 2124
Score = 256 bits (653), Expect = 2e-67
Identities = 218/751 (29%), Positives = 332/751 (44%), Gaps = 86/751 (11%)
Query: 17 PFRTFSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPP 76
P F+ + L HL +G +Y+GA N +++LS L L TGPV D+ C PP
Sbjct: 24 PPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPV 83
Query: 77 SVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRK--E 134
CP T+N N+LLL+ A L+ CGS QG+C+ RL L +L R
Sbjct: 84 MPDECPQAQ-PTNNPNQLLLVSPGA--LVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDT 140
Query: 135 HYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSSRRLMANEEDADMFG 194
Y+++ A S G++ G G+ + G G P +++R L + A
Sbjct: 141 QYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALWPPDPQA---A 197
Query: 195 FVYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHF 254
F Y++ K+ LS++ ++V +F Y+L L+ D Q S
Sbjct: 198 FSYEET-----AKLAVGRLSEYSH---HFVSAFARGASAYFLFLRRDLQAQS------RA 243
Query: 255 FTSKIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVL 314
F + + R+C+ D +YSYVE P+ CE G Y L+Q A ++ R +AH +VL
Sbjct: 244 FRAYVSRVCLRDQHYYSYVELPLACE--GGRYGLIQAAAVAT-SREVAHG-------EVL 293
Query: 315 FTVFAQGQKNRV-KPPKE-------SALCLFTLRAIKEKIKERIQSCYRGEGKLS----- 361
F F+ V +PP SALC F L + +CY EG+
Sbjct: 294 FAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEV 353
Query: 362 --LPWLLNKELGCINSPLQIDDDF-CGQDFN-QPLGGTVTIEGTPLFVDKDDGLTAVAAY 417
+ + +N + C P+ D + CG D P+ V +E TP+ LTAVA
Sbjct: 354 AYIEYDVNSD--CAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVT 411
Query: 418 DYRGRTVVFAGTRSGRIRKILVDLSNPG--GRPALAYESVVAQEGSPILRDLVLSPNHQY 475
G T+ F G G++ ++ + PG G P Y + Q+GS + RDL ++
Sbjct: 412 MEDGHTIAFLGDSQGQLHRVYL---GPGSDGHP---YSTQSIQQGSAVSRDLTFDGTFEH 465
Query: 476 LYAMTEKQVTRVPVESCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRFAA 535
LY MT+ + +VPV SC Q+ C CL RDP+CGWCVL CSRR C R P+++
Sbjct: 466 LYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLW 525
Query: 536 DL---LQCVQL-TVQPRNVSVTMSQVPLVLQAWNVPDLSAG--VNCSFEDFTESESVLED 589
L C+Q+ + P N+S ++ + L ++P L G +C F + +S ++L
Sbjct: 526 SFQPELGCLQVAAMSPANISREETR-EVFLSVPDLPPLWPGESYSCHFGEH-QSPALLTG 583
Query: 590 GRIHCRSPSAREVAPITRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCSV------HQS 643
+ C SP E + RG V + ++ + A FY+C
Sbjct: 584 SGVMCPSPDPSEAPVLPRGAD---YVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQ 640
Query: 644 CLSCVNGSFPCHWCKYRHVCTHNVADCAFLEGRVNVSEDCPQILPSTQIYVPVGVVKPIT 703
C +CV+ + C+WC ++H+CTH A C G + S P + P P
Sbjct: 641 CQACVSSRWGCNWCVWQHLCTHK-ASCD--AGPMVASHQSPLVSPDPPARGGPSPSPPTA 697
Query: 704 LAARNLPQPQSGQRGYECLFHIPGSPARVTA 734
A P P + L PG+P+ TA
Sbjct: 698 PKALATPAP-------DTLPVEPGAPSTATA 721
Score = 46.6 bits (109), Expect = 2e-04
Identities = 63/255 (24%), Positives = 94/255 (36%), Gaps = 36/255 (14%)
Query: 637 NCSVHQSCLSCVNGSFP-CHWCKYRHVCTHNVADCAFLEG------RVNVSEDCPQILPS 689
+C+ H C SC+ P C WC C+ ++C+ +G C Q+
Sbjct: 481 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRR-SECSRGQGPEQWLWSFQPELGCLQVAAM 539
Query: 690 TQIYVPVGVVKPITLAARNLPQPQSGQRGYECLFHIPGSPARVTALRFNSSSLQCQNSSY 749
+ + + + L+ +LP G+ Y C F SPA +T S +
Sbjct: 540 SPANISREETREVFLSVPDLPPLWPGE-SYSCHFGEHQSPALLTGSGVMCPSPDPSEAPV 598
Query: 750 SYEGNDVSDLPVNLSVVWNGNFVIDNPQNIQAHLYKCPALRE-----SCGLCLKADPRFE 804
G D + V L G VI Y C A+ E C C+ + R+
Sbjct: 599 LPRGADYVSVSVELRF---GAVVI---AKTSLSFYDCVAVTELRPSAQCQACVSS--RWG 650
Query: 805 CGWCVAERRCSLRHHCAADTPASWMH----------ARHGSSRC--TDPKILKL-SPETG 851
C WCV + C+ + C A P H AR G S T PK L +P+T
Sbjct: 651 CNWCVWQHLCTHKASCDAG-PMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTL 709
Query: 852 PRQGGTRLTITGENL 866
P + G T T ++
Sbjct: 710 PVEPGAPSTATASDI 724
Score = 33.5 bits (75), Expect = 2.0
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 10/81 (12%)
Query: 780 QAHLYKCP----ALRESCGLCLK-ADPRFECGWCVAERRCSLRHHCA-ADTPASWMHARH 833
Q+ L K P A C CL DP CGWCV RCS R C+ P W+ +
Sbjct: 471 QSTLLKVPVASCAQHLDCASCLAHRDPY--CGWCVLLGRCSRRSECSRGQGPEQWLWSFQ 528
Query: 834 GSSRCTDPKILKLSPETGPRQ 854
C ++ +SP R+
Sbjct: 529 PELGCL--QVAAMSPANISRE 547
>gi|157738647 plexin A4 isoform 3 [Homo sapiens]
Length = 492
Score = 471 bits (1212), Expect = e-132
Identities = 228/411 (55%), Positives = 297/411 (72%), Gaps = 2/411 (0%)
Query: 27 GLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPPSVQSCPHGLG 86
G HLVV E+TG +Y+GAVNRIYKLS +L +L H TGP EDN KCYPP VQ+C L
Sbjct: 50 GFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLT 109
Query: 87 STDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSVQEAGSM 146
+T+NVNK+LL+DY NRL+ACGS QGIC+ LRL+DLFKLGEP+H+KEHYLS V E+GS+
Sbjct: 110 TTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSV 169
Query: 147 AGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSSRRLMANEEDADMFGFVYQDEFVSSQL 206
GV+++ KLF+ T +DGK EYFPT+SSR+L N E MF +V+ DEFV+S +
Sbjct: 170 FGVIVSY--SNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMI 227
Query: 207 KIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHFFTSKIVRLCVDD 266
KIPSDT + P FDIYYVY F S FVY+LTLQ + E +TSK+VRLC +D
Sbjct: 228 KIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKED 287
Query: 267 PKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVLFTVFAQGQKNRV 326
F SYVE PIGCE++GVEYRL+Q AYLS+ G L LG+ D+D+LFTVF++GQK ++
Sbjct: 288 TAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKM 347
Query: 327 KPPKESALCLFTLRAIKEKIKERIQSCYRGEGKLSLPWLLNKELGCINSPLQIDDDFCGQ 386
K ESALC+F L+ I ++IKER+QSCYRGEG L L WL K++ C ++ L IDD+FCG
Sbjct: 348 KSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGL 407
Query: 387 DFNQPLGGTVTIEGTPLFVDKDDGLTAVAAYDYRGRTVVFAGTRSGRIRKI 437
D N PLG + + G P+F + D +T+V AY Y+ ++ F GT+SG+++K+
Sbjct: 408 DMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKM 458
>gi|157738643 plexin A4 isoform 2 [Homo sapiens]
Length = 522
Score = 471 bits (1211), Expect = e-132
Identities = 228/410 (55%), Positives = 296/410 (72%), Gaps = 2/410 (0%)
Query: 27 GLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPPSVQSCPHGLG 86
G HLVV E+TG +Y+GAVNRIYKLS +L +L H TGP EDN KCYPP VQ+C L
Sbjct: 50 GFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLT 109
Query: 87 STDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSVQEAGSM 146
+T+NVNK+LL+DY NRL+ACGS QGIC+ LRL+DLFKLGEP+H+KEHYLS V E+GS+
Sbjct: 110 TTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSV 169
Query: 147 AGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSSRRLMANEEDADMFGFVYQDEFVSSQL 206
GV+++ KLF+ T +DGK EYFPT+SSR+L N E MF +V+ DEFV+S +
Sbjct: 170 FGVIVSY--SNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMI 227
Query: 207 KIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHFFTSKIVRLCVDD 266
KIPSDT + P FDIYYVY F S FVY+LTLQ + E +TSK+VRLC +D
Sbjct: 228 KIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKED 287
Query: 267 PKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVLFTVFAQGQKNRV 326
F SYVE PIGCE++GVEYRL+Q AYLS+ G L LG+ D+D+LFTVF++GQK ++
Sbjct: 288 TAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKM 347
Query: 327 KPPKESALCLFTLRAIKEKIKERIQSCYRGEGKLSLPWLLNKELGCINSPLQIDDDFCGQ 386
K ESALC+F L+ I ++IKER+QSCYRGEG L L WL K++ C ++ L IDD+FCG
Sbjct: 348 KSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGL 407
Query: 387 DFNQPLGGTVTIEGTPLFVDKDDGLTAVAAYDYRGRTVVFAGTRSGRIRK 436
D N PLG + + G P+F + D +T+V AY Y+ ++ F GT+SG+++K
Sbjct: 408 DMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKK 457
>gi|5032223 plexin C1 [Homo sapiens]
Length = 1568
Score = 421 bits (1083), Expect = e-117
Identities = 267/706 (37%), Positives = 398/706 (56%), Gaps = 75/706 (10%)
Query: 1181 TQLLCEAPNLTGQHKVTVRAGGFEFSPGTLQVYSDS---------LLTLPAIVGIGGGGG 1231
T +LC+ + + + G L++Y + L+ LP
Sbjct: 903 TTILCKIKGIKTASTIANSSKKVRVKLGNLELYVEQESVPSTWYFLIVLPV--------- 953
Query: 1232 LLLLVIVAVLIAYKRKSRDADRTLKRLQLQMDNLESRVALECKEAFAELQTDIHELTNDL 1291
LL++VI A + + KS++ R + Q++ LES + E ++ FAELQ D ++ +
Sbjct: 954 LLVIVIFAAVGVTRHKSKELSRKQSQ---QLELLESELRKEIRDGFAELQMDKLDVVDSF 1010
Query: 1292 DGAGIPFLDYRTYAMRVLFP--GIEDHPVLKEMEVQANVEK--SLTLFGQLLTKKHFLLT 1347
+PFLDY+ +A+R FP G H ++M + +K SLT L+ K FL+T
Sbjct: 1011 --GTVPFLDYKHFALRTFFPESGGFTHIFTEDMHNRDANDKNESLTALDALICNKSFLVT 1068
Query: 1348 FIRTLEAQRSFSMRDRGNVASLIMTALQGEMEYATGVLKQLLSDLIEKNLESKNHPKLLL 1407
I TLE Q++FS++DR AS + ALQ ++ Y T +L+ L DL+E+ S PKL+L
Sbjct: 1069 VIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLTSILEVLTRDLMEQC--SNMQPKLML 1126
Query: 1408 RRTESVAEKMLTNWFTFLLYKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSE 1467
RRTESV EK+LTNW + L FL+E GEP ++L + Q++ KGP+D IT +A Y+L+E
Sbjct: 1127 RRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNE 1186
Query: 1468 DKLIRQQIDYKTLTLNCVN---PENENAP---EVPVKGLDCDTVTQAKEKLLDA--AYKG 1519
D L+ Q ++ T+ LN V PENE+A + V LDCDT+ QAKEK+ A + G
Sbjct: 1187 DWLLWQVPEFSTVALNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNG 1246
Query: 1520 VPYSQRPKAADMDLEWRQGRMARIILQDEDVTTKIDNDWKRLNTLAHYQVTDGSSVALVP 1579
PY + ++ LE + G + +L + + +++ +LNT+ HY++++GS++ +
Sbjct: 1247 SPYGLQLN--EIGLELQMGTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFK 1304
Query: 1580 KQTSAYNISNSSTFTKSLSRYESMLRTASSPDSLRSRTPMITPDLESGTKLWHLVKNHDH 1639
K I+N FT + + +I PD E+ D
Sbjct: 1305 K------IAN---FTSDVEYSDDHCH-------------LILPDSEAF---------QDV 1333
Query: 1640 LDQREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFL 1699
+R + V E+YLT+LL+TK + ++ LF +I+S + S P AIKY FDFL
Sbjct: 1334 QGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPN--SRAPFAIKYFFDFL 1391
Query: 1700 DEQADKHQIHDADVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTFMD 1759
D QA+ +I D DV H WK+N LPLRFWVN++KNPQFVFDI K D CLSV+AQ FMD
Sbjct: 1392 DAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPHIDGCLSVIAQAFMD 1451
Query: 1760 SCSTSEHKLGKDSPSNKLLYAKDIPNYKSWVERYYADIAKMPAISDQDMSAYLAEQSRLH 1819
+ S +E +LGK++P+NKLLYAKDIP YK V+ YY I +P +S +M +L ++S+ H
Sbjct: 1452 AFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSSSEMEEFLTQESKKH 1511
Query: 1820 LSQFNSMSALHEIYSYITKYKDEILAALEKD---EQARRQRLRSKL 1862
++FN AL EIY YI KY DEIL LE++ E+A++Q L K+
Sbjct: 1512 ENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKV 1557
Score = 89.4 bits (220), Expect = 3e-17
Identities = 95/396 (23%), Positives = 156/396 (39%), Gaps = 47/396 (11%)
Query: 298 GRALAHQLGLAEDEDVLFTVF--AQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSCYR 355
GR L L E DV VF A G+ + P +ALCLF + I+ + K
Sbjct: 290 GRRLLLSSSLVEALDVWAGVFSAAAGEGQERRSPTTTALCLFRMSEIQARAKR------- 342
Query: 356 GEGKLSLPWLLNKELGCINSPLQIDDDFCGQDFNQPLGGTVTIEGTPLFVDKDDGLTAVA 415
++ + + C ++ +QP T + D LT+V
Sbjct: 343 -----------------VSWDFKTAESHC-KEGDQPERVQPIASSTLIHSD----LTSVY 380
Query: 416 AYDYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDLVLSP-NHQ 474
RTV+F GT G++ K+++ + P + YE +E +P+ LV P +
Sbjct: 381 GTVVMNRTVLFLGTGDGQLLKVILGENLTSNCPEVIYE---IKEETPVFYKLVPDPVKNI 437
Query: 475 YLYAMTEKQVTRVPVESCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRFA 534
Y+Y K+V R+ V +C ++ SC CL + DPHCGWC C+ + C ++ + +
Sbjct: 438 YIYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENW- 496
Query: 535 ADLLQCVQLTVQPRNVSVTMSQVPLVLQAWNVPDLSAGVNCSFEDFTESESVLEDGRIHC 594
D+ + + + + + + + + P S C ++ S + ++
Sbjct: 497 LDISSGAKKCPKIQIIRSSKEKTTVTMVGSFSPRHS---KCMVKNVDSSRELCQNKSQPN 553
Query: 595 RSPSAREVAPITRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCSVHQSCLSCVNGSFPC 654
R+ + P D VV + G S F F NCS + C +CV C
Sbjct: 554 RTCTCS--IPTRATYKDVSVVNVMF---SFGSWNLSDRFNFTNCSSLKECPACVETG--C 606
Query: 655 HWCKYRHVCTHNVADCAFLEGRVNVSEDCPQILPST 690
WCK C H C + N E CP + T
Sbjct: 607 AWCKSARRCIHPFTACDPSDYERN-QEQCPVAVEKT 641
Score = 40.4 bits (93), Expect = 0.016
Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Query: 791 ESCGLCLKA-DPRFECGWCVAERRCSLRHHCA-ADTPASWMHARHGSSRCTDPKILKLSP 848
+SC CL A DP CGWC + +RC+ + C ++ +W+ G+ +C +I++ S
Sbjct: 459 KSCSECLTATDPH--CGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKIQIIRSSK 516
Query: 849 E 849
E
Sbjct: 517 E 517
>gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]
Length = 1390
Score = 150 bits (379), Expect = 1e-35
Identities = 140/540 (25%), Positives = 246/540 (45%), Gaps = 83/540 (15%)
Query: 28 LTHLVVHEQTGEVYVGAVNRIYKLSG-NLTLLRAHVTGPVEDNEKCYPPPSVQSCPHGLG 86
+ ++++HE +++GA N IY L+ +L + + TGPV ++ C+P S + G
Sbjct: 52 IQNVILHEH--HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSG 109
Query: 87 ST--DNVNKLLLLD-YAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSV--- 140
DN+N L++D Y ++L++CGS ++G CQ + PH+ S V
Sbjct: 110 GVWKDNINMALVVDTYYDDQLISCGSVNRGTCQ--------RHVFPHNHTADIQSEVHCI 161
Query: 141 -----QEAG-------SMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFP-----TLSSRRL 183
+E S G + FVG I+ S YFP ++S RRL
Sbjct: 162 FSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTIN--SSYFPDHPLHSISVRRL 219
Query: 184 MANEEDADMFGFVYQDEFVSSQLKIPSDTLSKF-PAFDIYYVYSFRSEQFVYYLTLQLDT 242
+E D F F+ ++ D L +F ++ I YV++F S F+Y+LT+Q +T
Sbjct: 220 ---KETKDGFMFLTDQSYI--------DVLPEFRDSYPIKYVHAFESNNFIYFLTVQRET 268
Query: 243 QLTSPDAAGEHFFTSKIVRLCVDDPKFYSYVEFPIGC---------EQAGVEYRLVQDAY 293
DA H ++I+R C + +SY+E P+ C + ++Q AY
Sbjct: 269 L----DAQTFH---TRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAY 321
Query: 294 LSRPGRALAHQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQS- 352
+S+PG LA Q+G + ++D+LF VFAQ + + +P SA+C F ++ + + + +
Sbjct: 322 VSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKN 381
Query: 353 ---CYRGEGKLSLPWLLNKELGCINSPLQIDDDFCGQDFNQPLGGTVTIEGTPLFVDK-- 407
C + + N+ L +S + D +F T ++ LF+ +
Sbjct: 382 NVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF------TTALQRVDLFMGQFS 435
Query: 408 DDGLTAVAAYDYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDL 467
+ LT+++ + T+ GT GR +++V S P P + + ++ +
Sbjct: 436 EVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGP-STPHVNFLLDSHPVSPEVIVEH 494
Query: 468 VLSPNHQYLYAMTEKQVTRVPVE--SCVQYTSCELCLGSRD-PHCGWCVLHSICSRRDAC 524
L+ N Y +T K++T++P+ C + SC CL + CGWC H C R + C
Sbjct: 495 TLNQN-GYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWC--HDKCVRSEEC 551
Score = 134 bits (337), Expect = 8e-31
Identities = 107/408 (26%), Positives = 182/408 (44%), Gaps = 42/408 (10%)
Query: 791 ESCGLCLKADPRFECGWCVAERRCSLRHHCAADTPASWMHARHGSSRCTDPKILKLSPET 850
+SC CL A P +CGWC +C C + T W + + P I K+ P +
Sbjct: 524 QSCSQCLSAPPFVQCGWC--HDKCVRSEECLSGT---W------TQQICLPAIYKVFPNS 572
Query: 851 GPRQGGTRLTITGENLGLR----FEDVRLGVRVGKVLCSPVESEYISAEQIVCEIGDASS 906
P +GGTRLTI G + G R F+ + V +G C+ SE + + C +G A +
Sbjct: 573 APLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSES-TMNTLKCTVGPAMN 631
Query: 907 VRAHDALVEVCVRDCSPHYRALSPKRFTFVTPTFYRVSPSRGPLSGGTWIGIEGSHLNAG 966
+ +++ S + F++V P +SP GP++GGT + + G++LN+G
Sbjct: 632 KHFNMSII------ISNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSG 685
Query: 967 SDVAVSVGGRPCSFSWRNSREIRCLTPPGQSPGSAPIIININRAQLTNPEVK-YNYTEDP 1025
+ +S+GG+ C+ ++ + C TP + + I+ L N E ++Y EDP
Sbjct: 686 NSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKID---LANRETSIFSYREDP 742
Query: 1026 TILRIDPEWSINSGGTLLTVTGTNLATVREPR--IRAKYGGIERENGCLVYNDTTMV-CR 1082
+ I P S SGG+ +T G NL +V PR I G C +++ ++ C
Sbjct: 743 IVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCT 802
Query: 1083 APSVANPVRSPPELGERPDELGFVMDNVRSLLVLNSTSFLYYPDPVLEPLSPTGLLELKP 1142
PS+ P + F++D + S +Y +PV +P ++ +
Sbjct: 803 TPSLQQLNLQLP----LKTKAFFMLDGILS----KYFDLIYVHNPVFKPFEKPVMISMGN 854
Query: 1143 SSPLILKGRNLLPPAPGNSRLNYTVLIGSTPC-TLTVSETQLLCEAPN 1189
+ L +KG ++ P A L +G+ C + + +LC PN
Sbjct: 855 ENVLEIKGNDIDPEAVKGEVLK----VGNKSCENIHLHSEAVLCTVPN 898
>gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]
Length = 1408
Score = 150 bits (379), Expect = 1e-35
Identities = 140/540 (25%), Positives = 246/540 (45%), Gaps = 83/540 (15%)
Query: 28 LTHLVVHEQTGEVYVGAVNRIYKLSG-NLTLLRAHVTGPVEDNEKCYPPPSVQSCPHGLG 86
+ ++++HE +++GA N IY L+ +L + + TGPV ++ C+P S + G
Sbjct: 52 IQNVILHEH--HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSG 109
Query: 87 ST--DNVNKLLLLD-YAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSV--- 140
DN+N L++D Y ++L++CGS ++G CQ + PH+ S V
Sbjct: 110 GVWKDNINMALVVDTYYDDQLISCGSVNRGTCQ--------RHVFPHNHTADIQSEVHCI 161
Query: 141 -----QEAG-------SMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFP-----TLSSRRL 183
+E S G + FVG I+ S YFP ++S RRL
Sbjct: 162 FSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTIN--SSYFPDHPLHSISVRRL 219
Query: 184 MANEEDADMFGFVYQDEFVSSQLKIPSDTLSKF-PAFDIYYVYSFRSEQFVYYLTLQLDT 242
+E D F F+ ++ D L +F ++ I YV++F S F+Y+LT+Q +T
Sbjct: 220 ---KETKDGFMFLTDQSYI--------DVLPEFRDSYPIKYVHAFESNNFIYFLTVQRET 268
Query: 243 QLTSPDAAGEHFFTSKIVRLCVDDPKFYSYVEFPIGC---------EQAGVEYRLVQDAY 293
DA H ++I+R C + +SY+E P+ C + ++Q AY
Sbjct: 269 L----DAQTFH---TRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAY 321
Query: 294 LSRPGRALAHQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQS- 352
+S+PG LA Q+G + ++D+LF VFAQ + + +P SA+C F ++ + + + +
Sbjct: 322 VSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKN 381
Query: 353 ---CYRGEGKLSLPWLLNKELGCINSPLQIDDDFCGQDFNQPLGGTVTIEGTPLFVDK-- 407
C + + N+ L +S + D +F T ++ LF+ +
Sbjct: 382 NVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF------TTALQRVDLFMGQFS 435
Query: 408 DDGLTAVAAYDYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDL 467
+ LT+++ + T+ GT GR +++V S P P + + ++ +
Sbjct: 436 EVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGP-STPHVNFLLDSHPVSPEVIVEH 494
Query: 468 VLSPNHQYLYAMTEKQVTRVPVE--SCVQYTSCELCLGSRD-PHCGWCVLHSICSRRDAC 524
L+ N Y +T K++T++P+ C + SC CL + CGWC H C R + C
Sbjct: 495 TLNQN-GYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWC--HDKCVRSEEC 551
Score = 123 bits (309), Expect = 1e-27
Identities = 107/426 (25%), Positives = 182/426 (42%), Gaps = 60/426 (14%)
Query: 791 ESCGLCLKADPRFECGWCVAERRCSLRHHCAADTPASWMHARHGSSRCTDPKILKLSPET 850
+SC CL A P +CGWC +C C + T W + + P I K+ P +
Sbjct: 524 QSCSQCLSAPPFVQCGWC--HDKCVRSEECLSGT---W------TQQICLPAIYKVFPNS 572
Query: 851 GPRQGGTRLTITGENLGLR----FEDVRLGVRVGKVLCSPVESEYISAEQIVCEIGDASS 906
P +GGTRLTI G + G R F+ + V +G C+ SE + + C +G A +
Sbjct: 573 APLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSES-TMNTLKCTVGPAMN 631
Query: 907 VRAHDALVEVCVRDCSPHYRALSPKRFTFVTPTFYRVSPSRGPLSGGTWIGIEGSHLNAG 966
+ +++ S + F++V P +SP GP++GGT + + G++LN+G
Sbjct: 632 KHFNMSII------ISNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSG 685
Query: 967 SDVAVSVGGRPCSFSWRNSREIRCLTPPGQSPGSAPIIININRAQLTNPEVK-YNYTEDP 1025
+ +S+GG+ C+ ++ + C TP + + I+ L N E ++Y EDP
Sbjct: 686 NSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKID---LANRETSIFSYREDP 742
Query: 1026 TILRIDPEWS------------------INSGGTLLTVTGTNLATVREPR--IRAKYGGI 1065
+ I P S SGG+ +T G NL +V PR I G
Sbjct: 743 IVYEIHPTKSFISTWWKEPLNIVSFLFCFASGGSTITGVGKNLNSVSVPRMVINVHEAGR 802
Query: 1066 ERENGCLVYNDTTMV-CRAPSVANPVRSPPELGERPDELGFVMDNVRSLLVLNSTSFLYY 1124
C +++ ++ C PS+ P + F++D + S +Y
Sbjct: 803 NFTVACQHRSNSEIICCTTPSLQQLNLQLP----LKTKAFFMLDGILS----KYFDLIYV 854
Query: 1125 PDPVLEPLSPTGLLELKPSSPLILKGRNLLPPAPGNSRLNYTVLIGSTPC-TLTVSETQL 1183
+PV +P ++ + + L +KG ++ P A L +G+ C + + +
Sbjct: 855 HNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLK----VGNKSCENIHLHSEAV 910
Query: 1184 LCEAPN 1189
LC PN
Sbjct: 911 LCTVPN 916
>gi|153946393 macrophage stimulating 1 receptor precursor [Homo
sapiens]
Length = 1400
Score = 116 bits (290), Expect = 2e-25
Identities = 142/534 (26%), Positives = 218/534 (40%), Gaps = 94/534 (17%)
Query: 40 VYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPPSVQSC------PHGL-GSTDNVN 92
V+V NR++ L +L +++ TGP D P Q+C PHG G TD
Sbjct: 70 VFVAIRNRLHVLGPDLKSVQSLATGPAGD-------PGCQTCAACGPGPHGPPGDTDT-- 120
Query: 93 KLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEH--YLSSVQEAGSMAGVL 150
K+L+LD A L++CGS+ QG C L DL G H S+
Sbjct: 121 KVLVLDPALPALVSCGSSLQGRCF---LHDLEPQGTAVHLAAPACLFSAHHNRPDDCPDC 177
Query: 151 IAGPPG-------QGQAKLF-VGTPIDGKSEYFPTLSSRRLMANEEDADMFGFVYQDEFV 202
+A P G QGQA F V + +D + + S R + AD GF FV
Sbjct: 178 VASPLGTRVTVVEQGQASYFYVASSLD--AAVAASFSPRSVSIRRLKADASGFA--PGFV 233
Query: 203 SSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHFFTSKIVRL 262
+ + +P +S + I YV+SF + FVY+LT+Q + P A +++ RL
Sbjct: 234 ALSV-LPKHLVS----YSIEYVHSFHTGAFVYFLTVQPASVTDDPSA-----LHTRLARL 283
Query: 263 CVDDPKFYSYVEFPIGCE-----------QAGVEYRLVQDAYLSRPGRALAHQLGLAEDE 311
+P+ Y E + C + G Y +++ A+ + G LA +L +AE +
Sbjct: 284 SATEPELGDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQ 343
Query: 312 DVLFTVFAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSC---------YRGEGKLSL 362
+VLF VF G+ S +C F + + I E ++ C RG
Sbjct: 344 EVLFGVFVTGKDGGPGVGPNSVVCAFPIDLLDTLIDEGVERCCESPVHPGLRRGLDFFQS 403
Query: 363 PWL---------LNKELGCINSPLQIDDDFCGQDFNQPLGGTVTIEGTPLFVDKDDGLTA 413
P L+ C + PL + F D L G V + T L+V + D +
Sbjct: 404 PSFCPNPPGLEALSPNTSCRHFPLLVSSSFSRVDLFNGLLGPVQV--TALYVTRLDNV-- 459
Query: 414 VAAYDYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDLVLSPNH 473
TV GT GRI + V+L + G P+ RD+ +H
Sbjct: 460 ---------TVAHMGTMDGRI--LQVELVRSLNYLLYVSNFSLGDSGQPVQRDVSRLGDH 508
Query: 474 QYLYAMTEKQVTRVPVE--SCVQYTSCELCLGS-RDPHCGWCVLHSICSRRDAC 524
L + QV +VP++ C + +C CL + CGWC ++C ++ C
Sbjct: 509 --LLFASGDQVFQVPIQGPGCRHFLTCGRCLRAWHFMGCGWC--GNMCGQQKEC 558
Score = 112 bits (279), Expect = 4e-24
Identities = 91/321 (28%), Positives = 135/321 (42%), Gaps = 37/321 (11%)
Query: 792 SCGLCLKADPRFECGWCVAERRCSLRHHCAADTPASWMHARHGSSRCTDPKILKLSPETG 851
+CG CL+A CGWC C + C P SW C PK+ + P +G
Sbjct: 532 TCGRCLRAWHFMGCGWC--GNMCGQQKEC----PGSWQQ-----DHCP-PKLTEFHPHSG 579
Query: 852 PRQGGTRLTITGENLGLR----FEDVRLGVRVGKVLCSPVESEYIS---------AEQIV 898
P +G TRLT+ G N L + V VG+ C P+ + E+
Sbjct: 580 PLRGSTRLTLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEEFE 639
Query: 899 CEIGDASSVRAHDALVEVCVRDCSP--HYRALSP---KRFTFVTPTFYRVSPSRGPLSGG 953
CE+ + V + V + P H+R + F+F+ P V P GP +GG
Sbjct: 640 CELEPLGTQAVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRAGG 699
Query: 954 TWIGIEGSHLNAGSDVAVSVGGRPCSFSWRNSREIRCLTPPGQSPGSAPIIININRAQLT 1013
T + +EG L+ G+ AV V G C + + ++ C TPPG + S P+ + + AQ+
Sbjct: 700 TCLTLEGQSLSVGTSRAVLVNGTECLLARVSEGQLLCATPPGATVASVPLSLQVGGAQVP 759
Query: 1014 NPEVKYNYTEDPTILRIDPEWS-INSGGTLLTVTGTNLATVREPRIRAKYGGIERENGCL 1072
+ Y EDP +L I P INS +T+ G +L + + G E+ C
Sbjct: 760 G-SWTFQYREDPVVLSISPNCGYINSH---ITICGQHLTSAWHLVLSFHDGLRAVESRCE 815
Query: 1073 VYNDTTMVCRAPSVANPVRSP 1093
+CR P VR P
Sbjct: 816 RQLPEQQLCRLPEYV--VRDP 834
>gi|21361914 semaphorin B [Homo sapiens]
Length = 761
Score = 71.6 bits (174), Expect = 7e-12
Identities = 102/442 (23%), Positives = 166/442 (37%), Gaps = 80/442 (18%)
Query: 95 LLLDYAANRLLACGS-ASQGICQFLRLDDLFKLGEPHHRKEHYLSSVQEAGSMAGVLIAG 153
+L+ Y L CG+ A C F+ L D YL + E M G
Sbjct: 130 VLVSYNVTHLYTCGTFAFSPACTFIELQD------------SYLLPISEDKVMEG----- 172
Query: 154 PPGQGQAKLFVGTPIDGKSEYFPTLSSRRLMANEEDADMFGFVYQDEFVSSQLKIPSDTL 213
+GQ+ P D ++ L L + + + + SQ + +D
Sbjct: 173 ---KGQS------PFDPAHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF 223
Query: 214 SKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHFFTSKIVRLCVDD------- 266
++ D +V + S Q VY+ + ++ E TS++ R+C +D
Sbjct: 224 LRWLHHDASFVAAIPSTQVVYFFFEETASEFDF----FERLHTSRVARVCKNDVGGEKLL 279
Query: 267 -PKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVLFTVFAQGQKN- 324
K+ ++++ + C Q G P + H + L D ++A
Sbjct: 280 QKKWTTFLKAQLLCTQPG-----------QLPFNVIRHAVLLPADSPTAPHIYAVFTSQW 328
Query: 325 RVKPPKESALCLFTL----RAIKEKIKERIQ-----SCYRGE------GKLSLPWLLNKE 369
+V + SA+C F+L R K K KE + + YRG G S+ +K
Sbjct: 329 QVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSCSVGPSSDKA 388
Query: 370 LGCINSPLQIDDDFCGQDFNQPLGGTVTIEGTPLFVDKDDGLTAVAAYDYRGRTVVFAGT 429
L + +D+ G PL +E T L V+ GL D V++ GT
Sbjct: 389 LTFMKDHFLMDEQVVGT----PLLVKSGVEYTRLAVETAQGL------DGHSHLVMYLGT 438
Query: 430 RSGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDLVLSPNHQYLYAMTEKQVTRVPV 489
+G + K +V G A E + +R+L L+P ++ V RVP
Sbjct: 439 TTGSLHKAVVS----GDSSAHLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPR 494
Query: 490 ESCVQYTSCELCLGSRDPHCGW 511
+C Y SC C+ +RDPHC W
Sbjct: 495 ANCSVYESCVDCVLARDPHCAW 516
>gi|39777610 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 68.2 bits (165), Expect = 7e-11
Identities = 122/544 (22%), Positives = 214/544 (39%), Gaps = 95/544 (17%)
Query: 12 GGSQPPFRTFSASDWG-LTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNE 70
G + PF F A T L++ +YVGA ++ LS NL+ L G ++
Sbjct: 53 GSEERPFLRFEAEHISNYTALLLSRDGRTLYVGAREALFALSSNLSFLPG---GEYQELL 109
Query: 71 KCYPPPSVQSCPHGLGST--DNVNKL-LLLDYAANRLLACGSAS-QGICQFLRLDDLFKL 126
Q C D N + +LL + + L CG+A+ +C ++ +++ F L
Sbjct: 110 WGADAEKKQQCSFKGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMEN-FTL 168
Query: 127 GEPHHRKEHYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYF----PTLSSRR 182
++ + + E G G P + A + G G F P +S +
Sbjct: 169 A-----RDEKGNVLLEDGK--GRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQ 221
Query: 183 LMANEEDADMFGFVYQDEFVSSQLKIPSDTLSKFPAFD--IYYVYSFRSEQFVYYLTLQL 240
+ + ++ FV+S IP ++L D IY+ +S ++F ++
Sbjct: 222 SLRPTKTESSLNWLQDPAFVASAY-IP-ESLGSLQGDDDKIYFFFSETGQEFEFF----- 274
Query: 241 DTQLTSPDAAGEHFFTSKIVRLCVDDP--------KFYSYVEFPIGCEQA--GVEYRLVQ 290
E+ S+I R+C D ++ S+++ + C + G + ++Q
Sbjct: 275 -----------ENTIVSRIARICKGDEGGERVLQQRWTSFLKAQLLCSRPDDGFPFNVLQ 323
Query: 291 DAYLSRPGRALAHQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLFTLRAIK------- 343
D + P + D LF Q +R + SA+C+FT++ ++
Sbjct: 324 DVFTLSPSPQ--------DWRDTLFYGVFTSQWHR-GTTEGSAVCVFTMKDVQRVFSGLY 374
Query: 344 EKIKERIQSCYRGEGKLSLPWLLNKELGCI---------NSPLQIDD---DFCGQDFNQP 391
+++ Q Y + P + CI NS LQ+ D +F F
Sbjct: 375 KEVNRETQQWYTVTHPVPTP----RPGACITNSARERKINSSLQLPDRVLNFLKDHFL-- 428
Query: 392 LGGTVTIEGTPLFVDKDDGLTAVAAYDYRGR----TVVFAGTRSGRIRKILVDLSNPGGR 447
+ G V L + VA + G V+F GT GR+ K + + G R
Sbjct: 429 MDGQV--RSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKAV----SVGPR 482
Query: 448 PALAYESVVAQEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVESCVQYTSCELCLGSRDP 507
+ E + G P+ ++L+L + LYA + V +VP+ +C Y SC CL +RDP
Sbjct: 483 VHIIEELQIFSSGQPV-QNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDP 541
Query: 508 HCGW 511
+C W
Sbjct: 542 YCAW 545
>gi|39777608 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 68.2 bits (165), Expect = 7e-11
Identities = 122/544 (22%), Positives = 214/544 (39%), Gaps = 95/544 (17%)
Query: 12 GGSQPPFRTFSASDWG-LTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNE 70
G + PF F A T L++ +YVGA ++ LS NL+ L G ++
Sbjct: 53 GSEERPFLRFEAEHISNYTALLLSRDGRTLYVGAREALFALSSNLSFLPG---GEYQELL 109
Query: 71 KCYPPPSVQSCPHGLGST--DNVNKL-LLLDYAANRLLACGSAS-QGICQFLRLDDLFKL 126
Q C D N + +LL + + L CG+A+ +C ++ +++ F L
Sbjct: 110 WGADAEKKQQCSFKGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMEN-FTL 168
Query: 127 GEPHHRKEHYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYF----PTLSSRR 182
++ + + E G G P + A + G G F P +S +
Sbjct: 169 A-----RDEKGNVLLEDGK--GRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQ 221
Query: 183 LMANEEDADMFGFVYQDEFVSSQLKIPSDTLSKFPAFD--IYYVYSFRSEQFVYYLTLQL 240
+ + ++ FV+S IP ++L D IY+ +S ++F ++
Sbjct: 222 SLRPTKTESSLNWLQDPAFVASAY-IP-ESLGSLQGDDDKIYFFFSETGQEFEFF----- 274
Query: 241 DTQLTSPDAAGEHFFTSKIVRLCVDDP--------KFYSYVEFPIGCEQA--GVEYRLVQ 290
E+ S+I R+C D ++ S+++ + C + G + ++Q
Sbjct: 275 -----------ENTIVSRIARICKGDEGGERVLQQRWTSFLKAQLLCSRPDDGFPFNVLQ 323
Query: 291 DAYLSRPGRALAHQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLFTLRAIK------- 343
D + P + D LF Q +R + SA+C+FT++ ++
Sbjct: 324 DVFTLSPSPQ--------DWRDTLFYGVFTSQWHR-GTTEGSAVCVFTMKDVQRVFSGLY 374
Query: 344 EKIKERIQSCYRGEGKLSLPWLLNKELGCI---------NSPLQIDD---DFCGQDFNQP 391
+++ Q Y + P + CI NS LQ+ D +F F
Sbjct: 375 KEVNRETQQWYTVTHPVPTP----RPGACITNSARERKINSSLQLPDRVLNFLKDHFL-- 428
Query: 392 LGGTVTIEGTPLFVDKDDGLTAVAAYDYRGR----TVVFAGTRSGRIRKILVDLSNPGGR 447
+ G V L + VA + G V+F GT GR+ K + + G R
Sbjct: 429 MDGQV--RSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKAV----SVGPR 482
Query: 448 PALAYESVVAQEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVESCVQYTSCELCLGSRDP 507
+ E + G P+ ++L+L + LYA + V +VP+ +C Y SC CL +RDP
Sbjct: 483 VHIIEELQIFSSGQPV-QNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDP 541
Query: 508 HCGW 511
+C W
Sbjct: 542 YCAW 545
>gi|126116589 fibrocystin L [Homo sapiens]
Length = 4243
Score = 68.2 bits (165), Expect = 7e-11
Identities = 106/423 (25%), Positives = 161/423 (38%), Gaps = 54/423 (12%)
Query: 820 CAADTPASWMHARHGSSRCTDPKILKLSPETGPRQGGTRLTITGENLGLRFEDVRLGVRV 879
C+ D +W S T P +L +SP G + GT LTI G + V V
Sbjct: 1053 CSGDCGFTW------DSNIT-PLVLAISPSQGSYEEGTILTIVGSGFS---PSSAVTVSV 1102
Query: 880 GKVLCSPVESEYISAEQIVCEIGDASSVRAHDALVEVCVRDCSPHYRALSPKRFTFVTPT 939
G V CS + + +++ C+I + S A A V V + D + +
Sbjct: 1103 GPVGCSLLS---VDEKELKCQILNGS---AGHAPVAVSMADVGLAQNVGGEEFYFVYQSQ 1156
Query: 940 FYRVSPSRGPLSGGTWIGIEGSHLNAGSDVAVSVGGRPCSFSWRNSREIRCLTPPGQSPG 999
+ P G ++GGT + + G N S V VG C+ + I C TP ++ G
Sbjct: 1157 ISHIWPDSGSIAGGTLLTLSGFGFNENSKVL--VGNETCNVIEGDLNRITCRTPK-KTEG 1213
Query: 1000 SAPIIININRAQLTNPEV-KYNYTEDPTILRIDPEWSINSGGTLLTVTGTNLATVREPRI 1058
+ I + N Q T + YN + P I P+ G LT+ G N +
Sbjct: 1214 TVDISVTTNGFQATARDAFSYNCLQTPIITDFSPKVRTILGEVNLTIKGYNFGNELTQNM 1273
Query: 1059 RAKYGGIERENGCLVYNDTTMVCRAPSVANPVRSPPELGERPDELGFVMDNVRSLLVLNS 1118
GG + L +N T + C P + SP + + + + R L +
Sbjct: 1274 AVYVGG--KTCQILHWNFTDIRCLLPKL-----SPGKHDIYVEVRNWGFASTRDKL---N 1323
Query: 1119 TSFLYYPDPVLEPLSPTGLLELKPSSPLILKGRNLLPPAPGNSRL--NYTVLIGSTPCTL 1176
+S Y VLE S + P + G + G S + TVL+GS PC +
Sbjct: 1324 SSIQY----VLEVTS------MFPQRGSLFGGTEITIRGFGFSTIPAENTVLLGSIPCNV 1373
Query: 1177 T-VSETQLLC------EAPNLTGQHKVTVRAGGFEFSPGTLQVYSDSLL-----TLPAIV 1224
T SE + C +T K +V G+ +SP L V + T P +
Sbjct: 1374 TSSSENVIKCILHSTGNIFRITNNGKDSVHGLGYAWSPPVLNVSVGDTVAWHWQTHPFLR 1433
Query: 1225 GIG 1227
GIG
Sbjct: 1434 GIG 1436
Score = 62.8 bits (151), Expect = 3e-09
Identities = 57/219 (26%), Positives = 95/219 (43%), Gaps = 20/219 (9%)
Query: 813 RCSLRHHCAADTPASWMHARHGSSRCT-----DPKILKLSPETGPRQGGTRLTITGENLG 867
+C + H P H GS+ T I ++P G GG +T+TG G
Sbjct: 1966 QCIVGDHAGGTFPVMMHHKTKGSAMSTVVFEYPLNIQNINPSQGSFGGGQTMTVTGT--G 2023
Query: 868 LRFEDVRLGVRVGKVLCSPVESEYISAEQIVCEIGDASSVRAHDALVEVCVRDCSPHYRA 927
++ + V + + S+Y + ++CEI + A A EV V + ++
Sbjct: 2024 FNPQNSIILVCGSECAIDRLRSDYTT---LLCEIPSNNGTGAEQAC-EVSVVNGKDLSQS 2079
Query: 928 LSPKRFTF---VTPTFYRVSPSRGPLSGGTWIGIEGSHLNAG-SDVAVSVGGRPCSFSWR 983
++P FT+ +TP VSP RG +GGT + + GS + DV +++ C +
Sbjct: 2080 MTP--FTYAVSLTPLITAVSPKRGSTAGGTRLTVVGSGFSENMEDVHITIAEAKCDVEYS 2137
Query: 984 NSREIRCLTPPGQSPGSAPIIINI---NRAQLTNPEVKY 1019
N I C+T G AP+ ++I A+L N + Y
Sbjct: 2138 NKTHIICMTDAHTLSGWAPVCVHIRGVGMAKLDNADFLY 2176
Score = 55.8 bits (133), Expect = 4e-07
Identities = 83/344 (24%), Positives = 130/344 (37%), Gaps = 51/344 (14%)
Query: 855 GGTRLTITGENLGLRFEDVRLGVRVGKVLCSPVESEYISAEQIVCEIGDASSVRAHDALV 914
G ++ I GE LG ED+ + + + V I+A +G S V
Sbjct: 1761 GSVKVLIEGEGLGTVLEDIAVFIGNQQFRAIEVNENNITALVTPLPVGHHS--------V 1812
Query: 915 EVCVRDCSPHYRALSPKRFTFVTPTFYRVSPSRGPLSGGTWIGIEGSHLNAGSDVAVSVG 974
V V + L+ T +P +SP+ G + GGT + I G+ G + V++G
Sbjct: 1813 SVVVGS-----KGLALGNLTVSSPPVASLSPTSGSIGGGTTLVITGNGFYPG-NTTVTIG 1866
Query: 975 GRPCSFSWRNSREIRCLTPPGQSPGSAPIIININRAQLTNPEVKYNYT-EDPTILR-IDP 1032
PC N E+ C TP G + G + I +N + P + + Y ED LR I P
Sbjct: 1867 DEPCQIISINPNEVYCRTPAG-TTGMVDVKIFVN--TIAYPPLLFTYALEDTPFLRGIIP 1923
Query: 1033 EWSINSGGTLLTVTGTNLATVREPRIRAKYGGIERENGCLVYNDTTMVCRA-PSVANPVR 1091
S GT + +TG+N +G E ++ N V A SV +
Sbjct: 1924 --SRGPPGTEIEITGSN------------FGFEILEISVMINNIQCNVTMANDSVVQCIV 1969
Query: 1092 SPPELGERPDELGFVMDNVRSLLVLNSTSFLYYPDPVLEPLSPTGLLELKPSSPLILKGR 1151
G P +M + +++ F Y P + + PS G+
Sbjct: 1970 GDHAGGTFP----VMMHHKTKGSAMSTVVFEY----------PLNIQNINPSQGSFGGGQ 2015
Query: 1152 NLLPPAPGNSRLNYTVLIGSTPCT---LTVSETQLLCEAPNLTG 1192
+ G + N +L+ + C L T LLCE P+ G
Sbjct: 2016 TMTVTGTGFNPQNSIILVCGSECAIDRLRSDYTTLLCEIPSNNG 2059
Score = 54.3 bits (129), Expect = 1e-06
Identities = 64/256 (25%), Positives = 105/256 (41%), Gaps = 27/256 (10%)
Query: 834 GSSRCTDPKILKLSPETGPRQGGTRLTITGENLGLRFEDVRLGVRVGKVLCSPVESEYIS 893
G+ + P + LSP +G GGT L ITG F V +G C + I+
Sbjct: 1824 GNLTVSSPPVASLSPTSGSIGGGTTLVITGNG----FYPGNTTVTIGDEPCQIIS---IN 1876
Query: 894 AEQIVCEIGDASSVRAHDALVEVCVRDCSPHYRALSPKRFTFV---TPTFYRVSPSRGPL 950
++ C ++ +V+V + + A P FT+ TP + PSRGP
Sbjct: 1877 PNEVYCRTPAGTT-----GMVDVKI---FVNTIAYPPLLFTYALEDTPFLRGIIPSRGP- 1927
Query: 951 SGGTWIGIEGSHLNAG-SDVAVSVGGRPCSFSWRNSREIRCLTPPGQSPGSAPIIININR 1009
GT I I GS+ +++V + C+ + N ++C+ + G+ P++++
Sbjct: 1928 -PGTEIEITGSNFGFEILEISVMINNIQCNVTMANDSVVQCIV-GDHAGGTFPVMMHHKT 1985
Query: 1010 AQLTNPEVKYNYTEDPTILRIDPEWSINSGGTLLTVTGTNLATVREPRIRAKYGGIEREN 1069
V + Y + I I+P GG +TVTGT + G E
Sbjct: 1986 KGSAMSTVVFEYPLN--IQNINPSQGSFGGGQTMTVTGTGFNPQNSIILVC---GSECAI 2040
Query: 1070 GCLVYNDTTMVCRAPS 1085
L + TT++C PS
Sbjct: 2041 DRLRSDYTTLLCEIPS 2056
Score = 47.4 bits (111), Expect = 1e-04
Identities = 50/217 (23%), Positives = 86/217 (39%), Gaps = 21/217 (9%)
Query: 841 PKILKLSPETGPRQGGTRLTITGENLGLRFEDVRLGVRVGKVLCSPVESEYISAEQIVCE 900
P + + P GP GT + ITG N G FE + + V + + C+ + + + C
Sbjct: 1916 PFLRGIIPSRGPP--GTEIEITGSNFG--FEILEISVMINNIQCNVTMA---NDSVVQCI 1968
Query: 901 IGDASSVRAHDALVEVCVRDCSPHYRALSPKRFTFVTPTFYRVSPSRGPLSGGTWIGIEG 960
+GD H + A+S F + ++PS+G GG + + G
Sbjct: 1969 VGD------HAGGTFPVMMHHKTKGSAMSTVVFEYPL-NIQNINPSQGSFGGGQTMTVTG 2021
Query: 961 SHLNAGSDVAVSVGGRPCSFSWRNS--REIRCLTPPGQSPGS--APIIININRAQLTNPE 1016
+ N + + + V G C+ S + C P G+ A + +N L+
Sbjct: 2022 TGFNPQNSI-ILVCGSECAIDRLRSDYTTLLCEIPSNNGTGAEQACEVSVVNGKDLSQSM 2080
Query: 1017 VKYNYTED--PTILRIDPEWSINSGGTLLTVTGTNLA 1051
+ Y P I + P+ +GGT LTV G+ +
Sbjct: 2081 TPFTYAVSLTPLITAVSPKRGSTAGGTRLTVVGSGFS 2117
Score = 37.4 bits (85), Expect = 0.14
Identities = 48/172 (27%), Positives = 73/172 (42%), Gaps = 38/172 (22%)
Query: 841 PKILKLSPETGPRQGGTRLTITGE--------NLGLRFEDVRLGVRVGKV-----LCSPV 887
PK+ ++ P+ G G TRLTI GE N G+ ++ LG V + + V
Sbjct: 31 PKVTEIIPKYGSINGATRLTIRGEGFSQANQFNYGV--DNAELGNSVQLISSFQSITCDV 88
Query: 888 ESEYISAEQIVCEI----GDASSVRAHDALVEVCVRD-CSPHYRA--LSPKRFTFVTPTF 940
E + + QI C D+ +VR V V + C H + + +F TPT
Sbjct: 89 EKDASHSTQITCYTRAMPEDSYTVRVSVDGVPVTENNTCKGHINSWECTFNAKSFRTPTI 148
Query: 941 YRVSPSRGPLSGGTWIGIEGSHLN--AGSDVAVS------------VGGRPC 978
++P G + GT I I+G GS++A+S +GG PC
Sbjct: 149 RSITPLSG--TPGTLITIQGRIFTDVYGSNIALSSNGKNVRILRVYIGGMPC 198
Score = 36.2 bits (82), Expect = 0.31
Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 1/53 (1%)
Query: 943 VSPSRGPLSGGTWIGIEGSHLNAGS-DVAVSVGGRPCSFSWRNSREIRCLTPP 994
+ PS+G + GGT + I G + V V VGG PC I C TPP
Sbjct: 275 IFPSQGSIRGGTTLTISGRFFDQTDFPVRVLVGGEPCDILNVTENSICCKTPP 327
>gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]
Length = 1011
Score = 57.8 bits (138), Expect = 1e-07
Identities = 35/116 (30%), Positives = 57/116 (49%), Gaps = 16/116 (13%)
Query: 411 LTAVA----AYDYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVA--------- 457
LTA++ A Y+ TV+F G+ +G + K+L S ++ E + A
Sbjct: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480
Query: 458 -QEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVESCVQYTSC-ELCLGSRDPHCGW 511
+E ++ L L +H LY + R+P+ C +Y SC + C+ SRDP+CGW
Sbjct: 481 NEEDKKVI-SLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535
>gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]
Length = 597
Score = 57.8 bits (138), Expect = 1e-07
Identities = 35/116 (30%), Positives = 57/116 (49%), Gaps = 16/116 (13%)
Query: 411 LTAVA----AYDYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVA--------- 457
LTA++ A Y+ TV+F G+ +G + K+L S ++ E + A
Sbjct: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480
Query: 458 -QEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVESCVQYTSC-ELCLGSRDPHCGW 511
+E ++ L L +H LY + R+P+ C +Y SC + C+ SRDP+CGW
Sbjct: 481 NEEDKKVI-SLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535
>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
Length = 1073
Score = 57.8 bits (138), Expect = 1e-07
Identities = 35/116 (30%), Positives = 57/116 (49%), Gaps = 16/116 (13%)
Query: 411 LTAVA----AYDYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVA--------- 457
LTA++ A Y+ TV+F G+ +G + K+L S ++ E + A
Sbjct: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480
Query: 458 -QEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVESCVQYTSC-ELCLGSRDPHCGW 511
+E ++ L L +H LY + R+P+ C +Y SC + C+ SRDP+CGW
Sbjct: 481 NEEDKKVI-SLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535
>gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
Length = 1017
Score = 57.8 bits (138), Expect = 1e-07
Identities = 35/116 (30%), Positives = 57/116 (49%), Gaps = 16/116 (13%)
Query: 411 LTAVA----AYDYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVA--------- 457
LTA++ A Y+ TV+F G+ +G + K+L S ++ E + A
Sbjct: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480
Query: 458 -QEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVESCVQYTSC-ELCLGSRDPHCGW 511
+E ++ L L +H LY + R+P+ C +Y SC + C+ SRDP+CGW
Sbjct: 481 NEEDKKVI-SLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535
>gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]
Length = 998
Score = 57.8 bits (138), Expect = 1e-07
Identities = 35/116 (30%), Positives = 57/116 (49%), Gaps = 16/116 (13%)
Query: 411 LTAVA----AYDYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVA--------- 457
LTA++ A Y+ TV+F G+ +G + K+L S ++ E + A
Sbjct: 421 LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAE 480
Query: 458 -QEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVESCVQYTSC-ELCLGSRDPHCGW 511
+E ++ L L +H LY + R+P+ C +Y SC + C+ SRDP+CGW
Sbjct: 481 NEEDKKVI-SLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535
>gi|157388902 semaphorin 4C [Homo sapiens]
Length = 833
Score = 57.4 bits (137), Expect = 1e-07
Identities = 42/122 (34%), Positives = 60/122 (49%), Gaps = 11/122 (9%)
Query: 402 PLFVDKDDGLTAVAAYDYRGR-----TVVFAGTRSGRIRKILVDLSNPGGRPALAYESVV 456
PL V K T + A G TV+F GT G + K V L G E +
Sbjct: 411 PLLVKKGTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLKA-VSL----GPWVHLIEELQ 465
Query: 457 AQEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVESCVQYTSCELCLGSRDPHCGWCVLHS 516
+ P +R LVLS + + L+A + Q+ ++PV C++Y SC C+ +RDP+C W V S
Sbjct: 466 LFDQEP-MRSLVLSQSKKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTS 524
Query: 517 IC 518
C
Sbjct: 525 RC 526
>gi|147904700 semaphorin 5A [Homo sapiens]
Length = 1074
Score = 54.7 bits (130), Expect = 8e-07
Identities = 29/122 (23%), Positives = 58/122 (47%), Gaps = 4/122 (3%)
Query: 402 PLFVDKDDGLTAVAAYDYRGRT----VVFAGTRSGRIRKILVDLSNPGGRPALAYESVVA 457
P F++ + + VA +GR +++ T G I+K+ V L+ L +
Sbjct: 393 PSFMEDNSRFSHVAVDVVQGREALVHIIYLATDYGTIKKVRVPLNQTSSSCLLEEIELFP 452
Query: 458 QEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVESCVQYTSCELCLGSRDPHCGWCVLHSI 517
+ +R L + + L+ + V ++P++ C Y + C+G++DP+CGW V+
Sbjct: 453 ERRREPIRSLQILHSQSVLFVGLREHVVKIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKK 512
Query: 518 CS 519
C+
Sbjct: 513 CT 514
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 52.4 bits (124), Expect = 4e-06
Identities = 34/96 (35%), Positives = 44/96 (45%)
Query: 424 VVFAGTRSGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDLVLSPNHQYLYAMTEKQ 483
V++ GT SG I K L S L V+ LR L + + + L+
Sbjct: 488 VLYIGTESGTILKALSTASRSLHGCYLEELHVLPPGRREPLRSLRILHSARALFVGLRDG 547
Query: 484 VTRVPVESCVQYTSCELCLGSRDPHCGWCVLHSICS 519
V RVP+E C Y S CLG+RDP+CGW CS
Sbjct: 548 VLRVPLERCAAYRSQGACLGARDPYCGWDGKQQRCS 583
>gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens]
Length = 749
Score = 51.6 bits (122), Expect = 7e-06
Identities = 124/535 (23%), Positives = 204/535 (38%), Gaps = 110/535 (20%)
Query: 31 LVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTG---PVEDNEKCYPPPSVQSCPHGLGS 87
L+V E+ G ++VGA N + L+ + RA PVE E+C +G
Sbjct: 58 LLVDEERGRLFVGAENHVASLNLDNISKRAKKLAWPAPVEWREEC------NWAGKDIG- 110
Query: 88 TDNVNKLLLLD-YAANRLLACGS-ASQGICQFLRLDDLFKLGEPHHRKEHYLSSVQEAGS 145
T+ +N + LL Y LLACG+ A C F+ E HR E
Sbjct: 111 TECMNFVKLLHAYNRTHLLACGTGAFHPTCAFV---------EVGHRAEE---------- 151
Query: 146 MAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSSRRLMANEE-----DADMFG---FVY 197
VL P K GKS Y P + ++ EE AD+ G ++
Sbjct: 152 --PVLRLDPGRIEDGK--------GKSPYDPRHRAASVLVGEELYSGVAADLMGRDFTIF 201
Query: 198 QDEFVSSQLKI-PSDT--LSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHF 254
+ L+ P D+ L++ ++++ + +T + + A G
Sbjct: 202 RSLGQRPSLRTEPHDSRWLNEPKFVKVFWIPESENPDDDKIYFFFRETAVEAAPALGR-L 260
Query: 255 FTSKIVRLCVDDP--------KFYSYVEFPIGCEQAGVE----YRLVQDAYL--SRPGRA 300
S++ ++C +D K+ ++++ + C GVE + +QD +L SR R
Sbjct: 261 SVSRVGQICRNDVGGQRSLVNKWTTFLKARLVCSVPGVEGDTHFDQLQDVFLLSSRDHRT 320
Query: 301 LAHQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLFTLRAIKEKI------KERIQS-- 352
+L+ VF+ + SA+C++++ ++ KE
Sbjct: 321 -----------PLLYAVFSTSSSIF----QGSAVCVYSMNDVRRAFLGPFAHKEGPMHQW 365
Query: 353 -CYRGEGKLSLPWLL-NKELGCINSPLQIDDDFCGQDFNQPL--GGTVTIEGTPLFVDKD 408
Y+G P + +K G +S DD N PL + G PLF+
Sbjct: 366 VSYQGRVPYPRPGMCPSKTFGTFSSTKDFPDDVIQFARNHPLMYNSVLPTGGRPLFLQVG 425
Query: 409 DGLT-------AVAAYDYRGRTVVFAGTRSGRIRKILVDLSNP-GGRPA---LAYESVVA 457
T VAA D V+F GT G + K++ S P G RP+ L E +
Sbjct: 426 ANYTFTQIAADRVAAADGH-YDVLFIGTDVGTVLKVI---SVPKGSRPSAEGLLLEELHV 481
Query: 458 QEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVESCVQYTS-CELCLGSRDPHCGW 511
E S + + +S LY + V ++ + C + C C +RDP+C W
Sbjct: 482 FEDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRVCTECCLARDPYCAW 536
>gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens]
Length = 748
Score = 51.2 bits (121), Expect = 9e-06
Identities = 124/535 (23%), Positives = 204/535 (38%), Gaps = 111/535 (20%)
Query: 31 LVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTG---PVEDNEKCYPPPSVQSCPHGLGS 87
L+V E+ G ++VGA N + L+ + RA PVE E+C +G
Sbjct: 58 LLVDEERGRLFVGAENHVASLNLDNISKRAKKLAWPAPVEWREEC------NWAGKDIG- 110
Query: 88 TDNVNKLLLLD-YAANRLLACGS-ASQGICQFLRLDDLFKLGEPHHRKEHYLSSVQEAGS 145
T+ +N + LL Y LLACG+ A C F+ E HR E
Sbjct: 111 TECMNFVKLLHAYNRTHLLACGTGAFHPTCAFV---------EVGHRAEE---------- 151
Query: 146 MAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSSRRLMANEE-----DADMFG---FVY 197
VL P K GKS Y P + ++ EE AD+ G ++
Sbjct: 152 --PVLRLDPGRIEDGK--------GKSPYDPRHRAASVLVGEELYSGVAADLMGRDFTIF 201
Query: 198 QDEFVSSQLKI-PSDT--LSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHF 254
+ L+ P D+ L++ ++++ + +T + + A G
Sbjct: 202 RSLGQRPSLRTEPHDSRWLNEPKFVKVFWIPESENPDDDKIYFFFRETAVEAAPALGR-L 260
Query: 255 FTSKIVRLCVDDP--------KFYSYVEFPIGCEQAGVE----YRLVQDAYL--SRPGRA 300
S++ ++C +D K+ ++++ + C GVE + +QD +L SR R
Sbjct: 261 SVSRVGQICRNDVGGQRSLVNKWTTFLKARLVCSVPGVEGDTHFDQLQDVFLLSSRDHRT 320
Query: 301 LAHQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLFTLRAIKEKI------KERIQS-- 352
+L+ VF+ + SA+C++++ ++ KE
Sbjct: 321 -----------PLLYAVFSTSSIFQ-----GSAVCVYSMNDVRRAFLGPFAHKEGPMHQW 364
Query: 353 -CYRGEGKLSLPWLL-NKELGCINSPLQIDDDFCGQDFNQPL--GGTVTIEGTPLFVDKD 408
Y+G P + +K G +S DD N PL + G PLF+
Sbjct: 365 VSYQGRVPYPRPGMCPSKTFGTFSSTKDFPDDVIQFARNHPLMYNSVLPTGGRPLFLQVG 424
Query: 409 DGLT-------AVAAYDYRGRTVVFAGTRSGRIRKILVDLSNP-GGRPA---LAYESVVA 457
T VAA D V+F GT G + K++ S P G RP+ L E +
Sbjct: 425 ANYTFTQIAADRVAAADGH-YDVLFIGTDVGTVLKVI---SVPKGSRPSAEGLLLEELHV 480
Query: 458 QEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVESCVQYTS-CELCLGSRDPHCGW 511
E S + + +S LY + V ++ + C + C C +RDP+C W
Sbjct: 481 FEDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRVCTECCLARDPYCAW 535
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,180,664
Number of Sequences: 37866
Number of extensions: 3630240
Number of successful extensions: 8879
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 8409
Number of HSP's gapped (non-prelim): 215
length of query: 1873
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1756
effective length of database: 13,817,196
effective search space: 24262996176
effective search space used: 24262996176
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.