Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 4826830
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo
sapiens]
(486 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens] 974 0.0
gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens] 957 0.0
gi|4505121 methyl-CpG binding domain protein 4 [Homo sapiens] 77 3e-14
gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo s... 74 3e-13
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 74 4e-13
gi|7710145 methyl-CpG binding domain protein 2 testis-specific i... 73 7e-13
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 66 6e-11
gi|104526627 triadin [Homo sapiens] 64 2e-10
gi|32307177 forkhead box G1 [Homo sapiens] 55 1e-07
gi|4505119 methyl-CpG binding domain protein 3 [Homo sapiens] 55 2e-07
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 54 4e-07
gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo ... 54 4e-07
gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo s... 54 4e-07
gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Ho... 54 4e-07
gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo ... 54 4e-07
gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo... 54 4e-07
gi|61966923 forkhead box B2 [Homo sapiens] 52 9e-07
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 52 1e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 52 1e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 52 1e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 52 1e-06
gi|239757043 PREDICTED: functional smad suppressing element 18 [... 52 1e-06
gi|239751555 PREDICTED: functional smad suppressing element 18 [... 52 1e-06
gi|239746067 PREDICTED: functional smad suppressing element 18 [... 52 1e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 52 1e-06
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 51 3e-06
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 51 3e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 50 4e-06
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 50 4e-06
gi|188536004 zinc finger protein 469 [Homo sapiens] 50 6e-06
>gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens]
Length = 486
Score = 974 bits (2518), Expect = 0.0
Identities = 486/486 (100%), Positives = 486/486 (100%)
Query: 1 MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAG 60
MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAG
Sbjct: 1 MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAG 60
Query: 61 KAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKY 120
KAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKY
Sbjct: 61 KAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKY 120
Query: 121 DVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPK 180
DVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPK
Sbjct: 121 DVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPK 180
Query: 181 APGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGAT 240
APGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGAT
Sbjct: 181 APGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGAT 240
Query: 241 TSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETV 300
TSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETV
Sbjct: 241 TSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETV 300
Query: 301 LPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASS 360
LPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASS
Sbjct: 301 LPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASS 360
Query: 361 PPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPR 420
PPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPR
Sbjct: 361 PPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPR 420
Query: 421 GGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTP 480
GGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTP
Sbjct: 421 GGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTP 480
Query: 481 VTERVS 486
VTERVS
Sbjct: 481 VTERVS 486
>gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens]
Length = 498
Score = 957 bits (2475), Expect = 0.0
Identities = 477/477 (100%), Positives = 477/477 (100%)
Query: 10 EEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSG 69
EEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSG
Sbjct: 22 EEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSG 81
Query: 70 SAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQG 129
SAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQG
Sbjct: 82 SAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQG 141
Query: 130 KAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRG 189
KAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRG
Sbjct: 142 KAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRG 201
Query: 190 RPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIK 249
RPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIK
Sbjct: 202 RPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIK 261
Query: 250 RPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTR 309
RPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTR
Sbjct: 262 RPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTR 321
Query: 310 ETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHH 369
ETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHH
Sbjct: 322 ETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHH 381
Query: 370 HHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGC 429
HHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGC
Sbjct: 382 HHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGC 441
Query: 430 PKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS 486
PKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS
Sbjct: 442 PKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS 498
>gi|4505121 methyl-CpG binding domain protein 4 [Homo sapiens]
Length = 580
Score = 77.4 bits (189), Expect = 3e-14
Identities = 39/70 (55%), Positives = 49/70 (70%), Gaps = 1/70 (1%)
Query: 99 TLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFT 158
++P GW R +KQR G++AG++DVY I+PQG FRSK L Y K G+TSL P DFDFT
Sbjct: 85 SVPCGWERVVKQRLFGKTAGRFDVYFISPQGLKFRSKSSLANYLHKNGETSLKPEDFDFT 144
Query: 159 V-TGRGSPSR 167
V + RG SR
Sbjct: 145 VLSKRGIKSR 154
>gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo
sapiens]
Length = 411
Score = 73.9 bits (180), Expect = 3e-13
Identities = 53/143 (37%), Positives = 71/143 (49%), Gaps = 15/143 (10%)
Query: 67 GSGSAPA-----VPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYD 121
G G AP P SA P R + G D P LP GW ++ RKSG SAGK D
Sbjct: 117 GGGGAPRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSD 176
Query: 122 VYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKA 181
VY +P GK FRSK +L Y +G+T +D + FDF TG+ PS+ ++ + P
Sbjct: 177 VYYFSPSGKKFRSKPQLARY---LGNT-VDLSSFDFR-TGKMMPSKLQKNKQRLRNDP-- 229
Query: 182 PGTGRGRGRPKGSGTTRPKAATS 204
+ +G+P TT P T+
Sbjct: 230 --LNQNKGKP-DLNTTLPIRQTA 249
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 73.6 bits (179), Expect = 4e-13
Identities = 107/469 (22%), Positives = 179/469 (38%), Gaps = 75/469 (15%)
Query: 35 KKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPM 94
++EEKE K E + E AE G+ ET +P EA++ K+ +S +++
Sbjct: 472 EEEEKEAKEEEGKEEEGGEEEEAEGGEEET-----KSPPAEEAASPEKEAKSPVKEEAKS 526
Query: 95 YDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPND 154
+ PE K+ + K +P + +S E
Sbjct: 527 PAEAKSPE------KEEAKSPAEVKSPEKAKSPAKEEAKSPPE----------------- 563
Query: 155 FDFTVTGRGSPSRREQKPPKKPKSP-KAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVL 213
SP + E K P + KSP KA + + + KA + + K
Sbjct: 564 -------AKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPA 616
Query: 214 E-KSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKP 272
E KSP K K P + KA+ S K P + + E + P+K + P
Sbjct: 617 EAKSPVKEEAKSPAEVKSPEKAK------SPTKEEAKSPEKAKSPEKEEAKSPEK-AKSP 669
Query: 273 GSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKR-KTRETVSIEVKEVVK-PLLVSTLGE 330
V A A + K K+ ++ +S ++ P+K+ K+ E VKE K P + +
Sbjct: 670 --VKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVK 727
Query: 331 KSGKGLKTCKSPGRKSKESSPKGRSS------SASSPPKKEHHHHHHHSESPKAPVPLLP 384
+ K + KSP ++ +S K +S SP K S + K P
Sbjct: 728 EEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKS 787
Query: 385 PLPPPPPEPESSEDPTSP---------PEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAK 435
P+ PE ++ P P+ +++ S V KEE+ P+ ++ P + A+
Sbjct: 788 PVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV-KEEEKPQEVKVKE---PPKKAE 843
Query: 436 TQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTER 484
+ A AT T +K + E +K+ P+P EE + P E+
Sbjct: 844 EEKAPATPKTEEKKDSKKEEAPKKE-----APKPKVEE---KKEPAVEK 884
Score = 71.2 bits (173), Expect = 2e-12
Identities = 111/511 (21%), Positives = 184/511 (36%), Gaps = 58/511 (11%)
Query: 7 GLREEKSEDQDLQG----LKDKPLKF-----KKVKKDKKEEKEGKHEPVQPSAHHSAEPA 57
G EE E+++ +G K P + K+ K KEE + E P + PA
Sbjct: 483 GKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPA 542
Query: 58 EAGKAE--TSEGSGSAPAVPEASA-------SPKQRRSIIRDRGPMYDDPTLPEGWTRKL 108
E E S A + PEA + SP + +S + + P ++ P
Sbjct: 543 EVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPE 602
Query: 109 KQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRG-SPSR 167
K + + K +P + +S E+ K + + P + + SP +
Sbjct: 603 KAKSPVKEEAKSPAEAKSPVKEEAKSPAEV-----KSPEKAKSPTKEEAKSPEKAKSPEK 657
Query: 168 REQKPPKKPKSP-----KAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLV 222
E K P+K KSP K+P + + + + K+ E + KSP K
Sbjct: 658 EEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPE-KAKSPVKEEA 716
Query: 223 KMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQA-----IPKKRGRKPGSVVA 277
K P + K E T +K + + P+ + + P A
Sbjct: 717 KSPEKAKSPVKEE--AKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEA 774
Query: 278 AAAAE---AKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGK 334
+ A+ K K+ + ++S ++ P+K+ I KE VK S + E+
Sbjct: 775 RSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVK----SPVKEEE-- 828
Query: 335 GLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPK--APVPLLPPLPPPPPE 392
K K KE K A + PK E E+PK AP P + P E
Sbjct: 829 -----KPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE 883
Query: 393 -PESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEP---AKTQPAVATAATAAE 448
P+ S+ E +D E++ P ++ D PKE AK +P A A ++
Sbjct: 884 KPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK 943
Query: 449 -KYKHRGEGERKDIVSSSMPRPNREEPVDSR 478
K E+KD +P + +++
Sbjct: 944 PAEKKEAAPEKKDTKEEKAKKPEEKPKTEAK 974
Score = 64.3 bits (155), Expect = 2e-10
Identities = 76/339 (22%), Positives = 124/339 (36%), Gaps = 35/339 (10%)
Query: 166 SRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMP 225
+ E+K K+ + + G G G K+ +E KSP K K P
Sbjct: 471 TEEEEKEAKEEEGKEEEG---GEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSP 527
Query: 226 FQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIP--KKRGRKPGSVVAAAAAE- 282
+ K E K P K +A++ P+A K+ + P V + A+
Sbjct: 528 AEAKSPEKEEAKSPAEVKSPEKAKSPA-KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKS 586
Query: 283 -AKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKS 341
AK++A + +S ++ P+K+ E K VK + K KS
Sbjct: 587 PAKEEAKSPAEAKSPEKAKSPVKEEAKSPA---EAKSPVK---------EEAKSPAEVKS 634
Query: 342 PGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESP-----KAPVPLLPPLPPPPPEPESS 396
P + + + +S + P+KE ++SP K+P P+ PE +
Sbjct: 635 PEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694
Query: 397 EDPTSPP--EPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRG 454
+ P P+ S V +E K P K P K + V A + EK K
Sbjct: 695 KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE 754
Query: 455 EGERKDIVSSSMPRPNREE--------PVDSRTPVTERV 485
+ + D+ S P +EE P +++PV E V
Sbjct: 755 KAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEV 793
Score = 60.8 bits (146), Expect = 3e-09
Identities = 99/433 (22%), Positives = 159/433 (36%), Gaps = 45/433 (10%)
Query: 10 EEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSG 69
E KS + +K++ +VK +K + K E P S E EA E ++
Sbjct: 611 EAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPV 670
Query: 70 SAPAV-PEASASP--KQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLIN 126
A A PE + SP + +S + + P+ ++ PE +K+ K V
Sbjct: 671 KAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA 730
Query: 127 PQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPP--KKPKSPKAPGT 184
+ +S V+ A + + D +P++ E + P K P+ K+P
Sbjct: 731 KTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVK 790
Query: 185 GRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTS---PGGKAEGGGATT 241
+ K + A E K+ KSP K K P + P KAE A
Sbjct: 791 EEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK-PQEVKVKEPPKKAEEEKAPA 849
Query: 242 STQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAV---KESSIRSVQE 298
+ P + K ++ + PKK KP E K+ AV KES + + +E
Sbjct: 850 T--------PKTEEKKDSKKEEAPKKEAPKP------KVEEKKEPAVEKPKESKVEAKKE 895
Query: 299 TVLPIKKRKTRET---VSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGR--KSKESSPKG 353
KK T E +EVKE KP + + +K K K P + + KE++P+
Sbjct: 896 EAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAK-AKEPSKPAEKKEAAPEK 954
Query: 354 RSSSASSPPKKEHHHHHHHSESPKAPVPLLP-----PLPPPPPEPESSEDPTSPPEPQDL 408
+ + K E E PK P P+ E +E +S +
Sbjct: 955 KDTKEEKAKKPE--------EKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSK 1006
Query: 409 SSSVCKEEKMPRG 421
E+K +G
Sbjct: 1007 PPEKATEDKAAKG 1019
Score = 40.0 bits (92), Expect = 0.005
Identities = 50/225 (22%), Positives = 82/225 (36%), Gaps = 13/225 (5%)
Query: 261 PQAIPKKRGRKPG-SVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEV 319
P ++P+ + P S +E K K V++S +V + + T E E KE
Sbjct: 419 PFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEA 478
Query: 320 VKPLLVSTLG---EKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESP 376
+ G E++ G + KSP + S K S K E
Sbjct: 479 KEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEA 538
Query: 377 KAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKT 436
K+P + P P E ++ P P+ +E K P ++S K PAK
Sbjct: 539 KSPAEVKSPEKAKSPAKEEAKSPPEAKSPEK------EEAKSP--AEVKSPEKAKSPAKE 590
Query: 437 QPAVATAATAAEKYKHRGEGERKDIVSSSMP-RPNREEPVDSRTP 480
+ A + EK K + E K + P + + P + ++P
Sbjct: 591 EAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSP 635
>gi|7710145 methyl-CpG binding domain protein 2 testis-specific
isoform [Homo sapiens]
Length = 302
Score = 72.8 bits (177), Expect = 7e-13
Identities = 47/118 (39%), Positives = 61/118 (51%), Gaps = 10/118 (8%)
Query: 67 GSGSAPA-----VPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYD 121
G G AP P SA P R + G D P LP GW ++ RKSG SAGK D
Sbjct: 117 GGGGAPRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSD 176
Query: 122 VYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSP 179
VY +P GK FRSK +L Y +G+T +D + FDF TG+ PS+ ++ + P
Sbjct: 177 VYYFSPSGKKFRSKPQLARY---LGNT-VDLSSFDFR-TGKMMPSKLQKNKQRLRNDP 229
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 66.2 bits (160), Expect = 6e-11
Identities = 49/176 (27%), Positives = 74/176 (42%), Gaps = 26/176 (14%)
Query: 254 KRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQ---ETVLPIKKRKTRE 310
KR+ D +P G K G VV ++++ ++K S+ ++ ET+ P R+
Sbjct: 615 KRQLSLDINKLP---GEKLGRVVHII--QSREPSLKNSNPDEIEIDFETLKPSTLRELER 669
Query: 311 TVSIEVKEVVKPLLVST---LGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPP----- 362
V+ +++ KP G KG + +S SS S + +P
Sbjct: 670 YVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKG 729
Query: 363 ------KKEHHHHHHHSESPKAPVPLLPP----LPPPPPEPESSEDPTSPPEPQDL 408
KK HHHHH + APVP PP PPPPP P+ + P PP P +
Sbjct: 730 HPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSM 785
Score = 38.9 bits (89), Expect = 0.011
Identities = 83/421 (19%), Positives = 155/421 (36%), Gaps = 38/421 (9%)
Query: 19 QGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGS----APAV 74
Q ++KP K +K KK+KK+EK + E V+ + A+ K + + S S
Sbjct: 530 QPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPA 589
Query: 75 PEASASPKQRRSIIRDR-GPM-YDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAF 132
P S P S D+ PM Y++ KL K GR V++I + +
Sbjct: 590 PMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRV-----VHIIQSREPSL 644
Query: 133 RSK--VELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGR 190
++ E+ FE + ++L + + VT R+++ P+ K G+ + +G
Sbjct: 645 KNSNPDEIEIDFETLKPSTL--RELERYVTS----CLRKKRKPQAEKVDVIAGSSKMKGF 698
Query: 191 PKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKR 250
+ ++++S+ E S ++ K + PG + + Q+
Sbjct: 699 SSSESESSSESSSSDS-------EDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPA 751
Query: 251 PGRKR---KAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRK 307
P ++ + P P ++ ++P + + +SS T +P+ + +
Sbjct: 752 PVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQ 811
Query: 308 TRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHH 367
+V + +P+L E + + S+P + A P H+
Sbjct: 812 LPGSVFDPIGHFTQPILHLPQPELP-------PHLPQPPEHSTPPHLNQHAVVSPPALHN 864
Query: 368 HHHHHSESPKAPVPLLPPLP--PPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLE 425
P LPP P PP P ++ P P P V E++ P L
Sbjct: 865 ALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLT 924
Query: 426 S 426
S
Sbjct: 925 S 925
Score = 38.5 bits (88), Expect = 0.014
Identities = 63/290 (21%), Positives = 103/290 (35%), Gaps = 39/290 (13%)
Query: 165 PSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKL---- 220
P +++Q+PP P P P + P + P AT QV + + PG +
Sbjct: 769 PPQQQQQPPPPPPPPSMPQ----QAAPAMKSSPPPFIAT----QVPVLEPQLPGSVFDPI 820
Query: 221 ------LVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGS 274
++ +P P + +T P + A P A+ ++P
Sbjct: 821 GHFTQPILHLPQPELPPHLPQPPEHSTP--------PHLNQHAVVSPPALHNALPQQPSR 872
Query: 275 VVAAAAAEAKKKAVKESSIRSVQET-VLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSG 333
AAA K A + ++ +T +LP V +E +E P L S +
Sbjct: 873 PSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYL 932
Query: 334 KGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEP 393
+ L+ + P P + S PP H + + P PP PPP P+P
Sbjct: 933 QQLQKVQPP----TPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQP----PPPPPPQPQP 984
Query: 394 ESSEDPTSPPEPQDLS----SSVCKEEKMPRGGSLESDGCPKEPAKTQPA 439
+ PP P L S+ ++ P+G ++P QPA
Sbjct: 985 PPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPA 1034
Score = 29.3 bits (64), Expect = 8.4
Identities = 24/101 (23%), Positives = 42/101 (41%), Gaps = 13/101 (12%)
Query: 318 EVVKPLLVSTLGEKSGKGLKTCKSPG-----RKSKESSPKGRSSSASSPPKKEHHHHHHH 372
E + ++V G G+ PG ++ S+P + +PP + H
Sbjct: 167 EETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFP 226
Query: 373 SESPKAPV--PLLPPLPP-----PPPEPESSEDPTSP-PEP 405
+ +P V P++ +PP PPP P + P +P P+P
Sbjct: 227 AVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQP 267
Score = 29.3 bits (64), Expect = 8.4
Identities = 32/130 (24%), Positives = 52/130 (40%), Gaps = 16/130 (12%)
Query: 316 VKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPK----KEHHHHHH 371
++E PL++ + + L P + + + R++S P KE H
Sbjct: 1059 LREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSP 1118
Query: 372 HSESPKAPVPLLPPLPPPPPE-PESSEDPTSPPE-----PQDLSSSVCK--EEKMPRGGS 423
S P P L P PP+ PES + P P+ P D+ V + E+ P G+
Sbjct: 1119 IIRSE----PFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGA 1174
Query: 424 LESDGCPKEP 433
+ D +EP
Sbjct: 1175 PDKDKQKQEP 1184
Score = 29.3 bits (64), Expect = 8.4
Identities = 38/153 (24%), Positives = 58/153 (37%), Gaps = 7/153 (4%)
Query: 164 SPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE-GVQVKRVLEKSPGKLLV 222
SPS R + PPK P+S KAP R K RP E +K K
Sbjct: 1126 SPSLRPE-PPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEP 1184
Query: 223 KMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADP-----QAIPKKRGRKPGSVVA 277
K P K + G+ S P K+ +D +A +K R+
Sbjct: 1185 KTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQ 1244
Query: 278 AAAAEAKKKAVKESSIRSVQETVLPIKKRKTRE 310
A AE +K+ +++ +RS ++ + R+ E
Sbjct: 1245 AEHAEKEKERLRQERMRSREDEDALEQARRAHE 1277
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 64.3 bits (155), Expect = 2e-10
Identities = 110/525 (20%), Positives = 195/525 (37%), Gaps = 72/525 (13%)
Query: 10 EEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSG 69
++ ED D + + PL+ K++ KDK E++E +Q H + E GK + E
Sbjct: 122 DDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEK--EKGKEKVRE--- 176
Query: 70 SAPAVPEASASPKQR---------RSIIRDRGPMYDDPTLPEGWTRKL---KQRKSGRSA 117
PE A+ K++ +++ +++ E +++ KQ K ++A
Sbjct: 177 --KEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTA 234
Query: 118 GKYDVYLINPQGKAFRSKVE--LIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKK 175
K P + E ++ E+ + D V G P + PP
Sbjct: 235 AKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPL 294
Query: 176 P------KSPKAPGTGRGRGRPKGSG---TTRPKAATSEGVQVKR-------VLEKSPGK 219
P +P +P G K + T+ K E ++ K V +K PGK
Sbjct: 295 PTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGK 354
Query: 220 L------LVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPG 273
VK+ Q + + + + + +++P K++ + + P K +K
Sbjct: 355 ASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEH 414
Query: 274 SVVAAAAAEAK-KKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKS 332
SV + +AK ++A +E S+++ V K+ KT +TV E+++ EKS
Sbjct: 415 SVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRK-----------EKS 463
Query: 333 GK--GLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPP 390
GK + K P + +E P K E PK P P
Sbjct: 464 GKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPE 523
Query: 391 PEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPA-KTQPAVATAATAAEK 449
P+ + P + Q + K EK S G P+E K AV TA K
Sbjct: 524 PQIKKEAKPAISEKVQIHKQDIVKPEK------TVSHGKPEEKVLKQVKAVTIEKTAKPK 577
Query: 450 YKHRGEGERKD--IVSSSMPRPNRE------EPVDSRTPVTERVS 486
+ E ++ + + P+P + E +T ++E+ S
Sbjct: 578 PTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKES 622
>gi|32307177 forkhead box G1 [Homo sapiens]
Length = 489
Score = 55.1 bits (131), Expect = 1e-07
Identities = 37/119 (31%), Positives = 44/119 (36%), Gaps = 24/119 (20%)
Query: 361 PPKKEHHHHHHHSESPKAPVPLLPPL-----PPPPPEPESSED----------------- 398
P HHHHHHH P AP P PP PPPPP P+ +
Sbjct: 45 PQHHHHHHHHHHHPPPPAPQPPPPPQQQQPPPPPPPAPQPPQTRGAPAADDDKGPQQLLL 104
Query: 399 PTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGE 457
P PP P + K + + GG E G P E A P A + +G GE
Sbjct: 105 PPPPPPPPAAALDGAKADGL--GGKGEPGGGPGELAPVGPDEKEKGAGAGGEEKKGAGE 161
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/102 (29%), Positives = 38/102 (37%), Gaps = 11/102 (10%)
Query: 358 ASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPP----EPQDLSSSVC 413
AS HH HHH P PP P PPP P+ + P PP PQ +
Sbjct: 35 ASHGHHNSHHPQHHHHHHHHHHHP-PPPAPQPPPPPQQQQPPPPPPPAPQPPQTRGAPAA 93
Query: 414 KEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGE 455
++K P+ L P PA A A+ +GE
Sbjct: 94 DDDKGPQQLLL------PPPPPPPPAAALDGAKADGLGGKGE 129
>gi|4505119 methyl-CpG binding domain protein 3 [Homo sapiens]
Length = 291
Score = 54.7 bits (130), Expect = 2e-07
Identities = 28/63 (44%), Positives = 38/63 (60%), Gaps = 4/63 (6%)
Query: 95 YDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPND 154
++ P LP+GW R+ R+SG SAG DV+ +P GK FRSK +L Y S+D +
Sbjct: 6 WECPALPQGWEREEVPRRSGLSAGHRDVFYYSPSGKKFRSKPQLARYL----GGSMDLST 61
Query: 155 FDF 157
FDF
Sbjct: 62 FDF 64
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 53.5 bits (127), Expect = 4e-07
Identities = 118/536 (22%), Positives = 183/536 (34%), Gaps = 101/536 (18%)
Query: 8 LREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEG 67
L+ SED D + +KP + EPV SAH S+ +E+ TS+
Sbjct: 427 LQLSDSEDSDSEQTPEKPPS----SSAPPSAPQSLPEPVA-SAHSSSAESES----TSDS 477
Query: 68 SGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLP----EGWTRKLKQRKSGRSAGKYDVY 123
S+ + E+S+S + + P + PT + W K+ Q + +
Sbjct: 478 DSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPR---- 533
Query: 124 LINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPG 183
P + SK + + S DP P + K P+ P P+AP
Sbjct: 534 STEPPRRHPESKGSSDSATSQEHSESKDP------------PPKSSSKAPRAP--PEAPH 579
Query: 184 TGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAE------GG 237
G+ R K P + G + K P K + +TS G+ E G
Sbjct: 580 PGK-RSCQKSPAQQEPPQRQTVGTK----QPKKPVKASARAGSRTSLQGEREPGLLPYGS 634
Query: 238 GATTSTQVMVIKRPGRKRKA---EADPQAIPKKRGRK-----PGSVVAAAAAEAKKKAVK 289
TS +K GR R A E P P +K P A + E K V+
Sbjct: 635 RDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVE 694
Query: 290 ESSIRSV------------------------QETVLPIKKRKTRETVSIEVKEVVKPL-- 323
+ + Q V+ RK R + + +++ PL
Sbjct: 695 DRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRD 754
Query: 324 --------------LVSTLGEKSGKGLKTCKS----PGRKSKESSPKGRSSSASSPPKKE 365
L+S + + GKG + K+ P K SS K S S+S KK
Sbjct: 755 TPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKR 814
Query: 366 HHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLE 425
++ K + L + SS +S +P SS K+E +P
Sbjct: 815 KGEAERDCDNKK--IRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSS 872
Query: 426 SDGCPKEPA--KTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRT 479
S P +PA +++ T K + KD SS+P+ R E SR+
Sbjct: 873 SSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKD---SSIPKQRRVEGKGSRS 925
Score = 31.6 bits (70), Expect = 1.7
Identities = 36/164 (21%), Positives = 59/164 (35%), Gaps = 21/164 (12%)
Query: 330 EKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPP 389
E G +SK+ PK S + +PP+ H +SP PP
Sbjct: 543 ESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQ-------EPP 595
Query: 390 PPEPESSEDPTSPPEPQDLSSSVC-----KEEKMPRGGSLESDGCPKEPAKTQPAVATAA 444
+ ++ P P + + S +E + GS + K KT+ AA
Sbjct: 596 QRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAA 655
Query: 445 TAAEKYKHRGEGERKDIVSSSMPRPNR--------EEPVDSRTP 480
+ K E+K SS+P P++ ++ V+ RTP
Sbjct: 656 SNEPKPAVPPSSEKKK-HKSSLPAPSKALSGPEPAKDNVEDRTP 698
Score = 31.2 bits (69), Expect = 2.2
Identities = 36/161 (22%), Positives = 57/161 (35%), Gaps = 21/161 (13%)
Query: 341 SPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPL-------------- 386
S +S+ +S SS + S + E+P AP P P
Sbjct: 466 SSSAESESTSDSDSSSDSESESSSSDSEENEPLETP-APEPEPPTTNKWQLDNWLTKVSQ 524
Query: 387 PPPPPE-PESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAAT 445
P PPE P S+E P PE + S S +E S D PK +K A A
Sbjct: 525 PAAPPEGPRSTEPPRRHPESKGSSDSATSQEH-----SESKDPPPKSSSKAPRAPPEAPH 579
Query: 446 AAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS 486
++ + +++ ++ ++PV + R S
Sbjct: 580 PGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTS 620
>gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo
sapiens]
Length = 586
Score = 53.5 bits (127), Expect = 4e-07
Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 7/113 (6%)
Query: 96 DDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 155
D P L GW R+ RKSG + G+ D Y +P G RSKVEL Y D +L F
Sbjct: 7 DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----F 62
Query: 156 DFTVTGRGSPSRREQK---PPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE 205
DF P+ + KK K P P R R SG R +A E
Sbjct: 63 DFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDE 115
>gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo
sapiens]
Length = 503
Score = 53.5 bits (127), Expect = 4e-07
Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 7/113 (6%)
Query: 96 DDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 155
D P L GW R+ RKSG + G+ D Y +P G RSKVEL Y D +L F
Sbjct: 7 DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----F 62
Query: 156 DFTVTGRGSPSRREQK---PPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE 205
DF P+ + KK K P P R R SG R +A E
Sbjct: 63 DFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDE 115
>gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Homo
sapiens]
Length = 556
Score = 53.5 bits (127), Expect = 4e-07
Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 7/113 (6%)
Query: 96 DDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 155
D P L GW R+ RKSG + G+ D Y +P G RSKVEL Y D +L F
Sbjct: 7 DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----F 62
Query: 156 DFTVTGRGSPSRREQK---PPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE 205
DF P+ + KK K P P R R SG R +A E
Sbjct: 63 DFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDE 115
>gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo
sapiens]
Length = 605
Score = 53.5 bits (127), Expect = 4e-07
Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 7/113 (6%)
Query: 96 DDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 155
D P L GW R+ RKSG + G+ D Y +P G RSKVEL Y D +L F
Sbjct: 7 DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----F 62
Query: 156 DFTVTGRGSPSRREQK---PPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE 205
DF P+ + KK K P P R R SG R +A E
Sbjct: 63 DFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDE 115
>gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo
sapiens]
Length = 549
Score = 53.5 bits (127), Expect = 4e-07
Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 7/113 (6%)
Query: 96 DDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 155
D P L GW R+ RKSG + G+ D Y +P G RSKVEL Y D +L F
Sbjct: 7 DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----F 62
Query: 156 DFTVTGRGSPSRREQK---PPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE 205
DF P+ + KK K P P R R SG R +A E
Sbjct: 63 DFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDE 115
>gi|61966923 forkhead box B2 [Homo sapiens]
Length = 432
Score = 52.4 bits (124), Expect = 9e-07
Identities = 32/85 (37%), Positives = 38/85 (44%), Gaps = 14/85 (16%)
Query: 366 HHHHHHHSESPKAPVPLLPPLPPPPPEPE---SSEDPTSPPEPQDLSSSVCKEEKMPRGG 422
HHHHHHH P PP PPPPP + PT+P P L S ++ P+
Sbjct: 155 HHHHHHHPPQPP------PPPPPPPPHMVHYFHQQPPTAPQPPPHLPSQ--PPQQPPQQS 206
Query: 423 SLESDGCPKEPAKTQPAVATAATAA 447
+ P P K Q A A AA AA
Sbjct: 207 QPQQ---PSHPGKMQEAAAVAAAAA 228
Score = 37.7 bits (86), Expect = 0.024
Identities = 27/99 (27%), Positives = 37/99 (37%), Gaps = 7/99 (7%)
Query: 361 PPKKEHHHHHHHSESPKAPVPL--LPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKM 418
PP H H+ H + P AP P LP PP P +S S P +++V
Sbjct: 170 PPPPPHMVHYFHQQPPTAPQPPPHLPSQPPQQPPQQSQPQQPSHPGKMQEAAAVAAAAAA 229
Query: 419 PRGGSLESDG-----CPKEPAKTQPAVATAATAAEKYKH 452
++ S G P A A AA + +KH
Sbjct: 230 AAAAAVGSVGRLSQFPPYGLGSAAAAAAAAAASTSGFKH 268
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 52.0 bits (123), Expect = 1e-06
Identities = 70/309 (22%), Positives = 109/309 (35%), Gaps = 30/309 (9%)
Query: 148 TSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAAT-SEG 206
T P T + +P+ E+ P P+ P P T P+ T PKAA +
Sbjct: 491 TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP-TPTT------PEEPAPTTPKAAAPNTP 543
Query: 207 VQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPK 266
+ K P K P T+P K T +K P + P+ +
Sbjct: 544 KEPAPTTPKEPAPTTPKEPAPTTP--KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 601
Query: 267 KRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVS 326
++P S A K ++ + T K T +K +
Sbjct: 602 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT---PKEPAPTTPKGTAPTTLKEPAPT 658
Query: 327 TLGEKSGKGLKTCKSPGRKSKES---SPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLL 383
T + + K L + G S S +P +A + PK+ +PK P P
Sbjct: 659 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA------PTTPKKPAPTT 712
Query: 384 PPLPPPPPE----PESSEDPTSPPEPQDLSSSVCKEEKMPRG--GSLESDGCP--KEPAK 435
P PPP P ++++PT+ + D S+ E P+ S + G P K PA
Sbjct: 713 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 772
Query: 436 TQPAVATAA 444
T+P + T A
Sbjct: 773 TKPEMTTTA 781
Score = 51.2 bits (121), Expect = 2e-06
Identities = 75/298 (25%), Positives = 96/298 (32%), Gaps = 35/298 (11%)
Query: 160 TGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGK 219
T + +P+ ++ P PK P AP T PK T PK T + K P
Sbjct: 290 TTKSAPTTPKEPAPTTPKKP-APTT------PKEPAPTTPKEPTPTTPKEPAPTTKEPAP 342
Query: 220 LLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADP----QAIPKKRGRKPGSV 275
K P T+P K K P E P + P P +
Sbjct: 343 TTPKEPAPTAP--KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 400
Query: 276 VAAAAAEAKKKAV--KESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSG 333
A K KE S + +E K T K +T E +
Sbjct: 401 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 460
Query: 334 KGLKTCKSPGRKS-KESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLP--PPP 390
T K P + KE +P +A + PKK +P P L P P P P
Sbjct: 461 T---TTKKPAPTTPKEPAPTTPKETAPTTPKKL---------TPTTPEKLAPTTPEKPAP 508
Query: 391 PEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAE 448
PE PT+P EP + EE P + PKEPA T P T E
Sbjct: 509 TTPEELA-PTTPEEP----TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561
Score = 50.4 bits (119), Expect = 4e-06
Identities = 106/483 (21%), Positives = 153/483 (31%), Gaps = 60/483 (12%)
Query: 30 KVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIR 89
+VK +KK + K P P + + G + + S + S SPK I
Sbjct: 65 EVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPK-----IT 119
Query: 90 DRGPMYDDPTLPEGWTRKLKQR---KSGRSAGKYDVYLINPQ----GKAFRSKVELIAYF 142
P+ P+LP + + + N Q GK + +
Sbjct: 120 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 179
Query: 143 EKVGDTSLDPND---------FDFTVTGRGSPSRREQKP--PKKPKS--PKAPGTGRGRG 189
EK L P + T G + +E P PK+P S PK P +
Sbjct: 180 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 239
Query: 190 RPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKA-----EGGGATTSTQ 244
P T PK + K P K P T+P A E TT +
Sbjct: 240 AP-----TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 294
Query: 245 VMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIK 304
K P + P PK+ + KE + + +E
Sbjct: 295 PTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 353
Query: 305 KRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLK-----TCKSPGRKSKESSPKGRSSSAS 359
K+ T K +T E S K T KS +KE +P S+ +
Sbjct: 354 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 413
Query: 360 SPPKKEHHHHHHHSESPKAPVPLLP--PLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEK 417
+P + + K P P P P P P +P PT+P EP + +E
Sbjct: 414 TPKEPS-------PTTTKEPAPTTPKEPAPTTPKKPA----PTTPKEP----APTTPKEP 458
Query: 418 MPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDS 477
P + PKEPA T P TA T +K E+ + P P E +
Sbjct: 459 APTTTKKPAPTTPKEPAPTTPK-ETAPTTPKKLTPT-TPEKLAPTTPEKPAPTTPEELAP 516
Query: 478 RTP 480
TP
Sbjct: 517 TTP 519
Score = 41.6 bits (96), Expect = 0.002
Identities = 52/200 (26%), Positives = 73/200 (36%), Gaps = 18/200 (9%)
Query: 297 QETVLPIKKRKTRETVSIEVKEVVKP-LLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRS 355
+ET L + K T +E KE ST G++ K +S + S +
Sbjct: 138 KETSLTVNKETT-----VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 192
Query: 356 SSASSPPKKEHHHHHHHSESPKAPVPLLPPLP----PPPPEPESSED-PTSPPEPQDL-- 408
A PK E +PK P P P P P P P + + PT+P EP
Sbjct: 193 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 252
Query: 409 -SSSVCKEEKMPRGGSLESDGCPKEPAKT---QPAVATAATAAEKYKHRGEGERKDIVSS 464
S+ +E P + PKEPA T +PA T +A K K +
Sbjct: 253 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 312
Query: 465 SMPRPNREEPVDSRTPVTER 484
+ P P + TP T +
Sbjct: 313 TPKEPAPTTPKEP-TPTTPK 331
Score = 38.9 bits (89), Expect = 0.011
Identities = 70/306 (22%), Positives = 111/306 (36%), Gaps = 38/306 (12%)
Query: 164 SPSRREQKPPKKPKSPK----APGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGK 219
+P+ ++ P PK P AP T +G + TT K A + + K P
Sbjct: 648 APTTLKEPAPTTPKKPAPKELAPTTTKGP-----TSTTSDKPAPTTPKETAPTTPKEPAP 702
Query: 220 LLVKMPF----QTSPGGKAEGGGATTSTQVMVI-KRPGRKR---KAEADPQAI---PKKR 268
K P +T P +E TT+ + I K P AE P+A+ PK+
Sbjct: 703 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 762
Query: 269 GRKPGSVVAAAAAE---AKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLV 325
G AA E K E +R+ ET K T+ET + K +
Sbjct: 763 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM-TKETATTTEKTTESKITA 821
Query: 326 STLGEKSGKGLKTC--KSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLL 383
+T S T K K+ +PK +++ + E + + PK
Sbjct: 822 TTTQVTSTTTQDTTPFKITTLKTTTLAPKV-TTTKKTITTTEIMNKPEETAKPKDRATNS 880
Query: 384 PPLPPPPPEP-ESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVAT 442
P P +P ++ + PTS +P + MPR ++ P++ T P +
Sbjct: 881 KATTPKPQKPTKAPKKPTSTKKP----------KTMPRVRKPKTTPTPRKMTSTMPELNP 930
Query: 443 AATAAE 448
+ AE
Sbjct: 931 TSRIAE 936
Score = 29.3 bits (64), Expect = 8.4
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 11/81 (13%)
Query: 167 RREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQ-VKRVLE----------K 215
++ K PKKP S K P T +PK + T R +T + R+ E +
Sbjct: 888 QKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQ 947
Query: 216 SPGKLLVKMPFQTSPGGKAEG 236
+P LV++ ++ G AEG
Sbjct: 948 TPNSKLVEVNPKSEDAGGAEG 968
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 52.0 bits (123), Expect = 1e-06
Identities = 70/309 (22%), Positives = 109/309 (35%), Gaps = 30/309 (9%)
Query: 148 TSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAAT-SEG 206
T P T + +P+ E+ P P+ P P T P+ T PKAA +
Sbjct: 532 TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP-TPTT------PEEPAPTTPKAAAPNTP 584
Query: 207 VQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPK 266
+ K P K P T+P K T +K P + P+ +
Sbjct: 585 KEPAPTTPKEPAPTTPKEPAPTTP--KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 642
Query: 267 KRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVS 326
++P S A K ++ + T K T +K +
Sbjct: 643 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT---PKEPAPTTPKGTAPTTLKEPAPT 699
Query: 327 TLGEKSGKGLKTCKSPGRKSKES---SPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLL 383
T + + K L + G S S +P +A + PK+ +PK P P
Sbjct: 700 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA------PTTPKKPAPTT 753
Query: 384 PPLPPPPPE----PESSEDPTSPPEPQDLSSSVCKEEKMPRG--GSLESDGCP--KEPAK 435
P PPP P ++++PT+ + D S+ E P+ S + G P K PA
Sbjct: 754 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 813
Query: 436 TQPAVATAA 444
T+P + T A
Sbjct: 814 TKPEMTTTA 822
Score = 51.2 bits (121), Expect = 2e-06
Identities = 75/298 (25%), Positives = 96/298 (32%), Gaps = 35/298 (11%)
Query: 160 TGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGK 219
T + +P+ ++ P PK P AP T PK T PK T + K P
Sbjct: 331 TTKSAPTTPKEPAPTTPKKP-APTT------PKEPAPTTPKEPTPTTPKEPAPTTKEPAP 383
Query: 220 LLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADP----QAIPKKRGRKPGSV 275
K P T+P K K P E P + P P +
Sbjct: 384 TTPKEPAPTAP--KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 441
Query: 276 VAAAAAEAKKKAV--KESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSG 333
A K KE S + +E K T K +T E +
Sbjct: 442 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 501
Query: 334 KGLKTCKSPGRKS-KESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLP--PPP 390
T K P + KE +P +A + PKK +P P L P P P P
Sbjct: 502 T---TTKKPAPTTPKEPAPTTPKETAPTTPKKL---------TPTTPEKLAPTTPEKPAP 549
Query: 391 PEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAE 448
PE PT+P EP + EE P + PKEPA T P T E
Sbjct: 550 TTPEELA-PTTPEEP----TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602
Score = 50.4 bits (119), Expect = 4e-06
Identities = 106/483 (21%), Positives = 153/483 (31%), Gaps = 60/483 (12%)
Query: 30 KVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIR 89
+VK +KK + K P P + + G + + S + S SPK I
Sbjct: 106 EVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPK-----IT 160
Query: 90 DRGPMYDDPTLPEGWTRKLKQR---KSGRSAGKYDVYLINPQ----GKAFRSKVELIAYF 142
P+ P+LP + + + N Q GK + +
Sbjct: 161 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 220
Query: 143 EKVGDTSLDPND---------FDFTVTGRGSPSRREQKP--PKKPKS--PKAPGTGRGRG 189
EK L P + T G + +E P PK+P S PK P +
Sbjct: 221 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 280
Query: 190 RPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKA-----EGGGATTSTQ 244
P T PK + K P K P T+P A E TT +
Sbjct: 281 AP-----TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 335
Query: 245 VMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIK 304
K P + P PK+ + KE + + +E
Sbjct: 336 PTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 394
Query: 305 KRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLK-----TCKSPGRKSKESSPKGRSSSAS 359
K+ T K +T E S K T KS +KE +P S+ +
Sbjct: 395 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 454
Query: 360 SPPKKEHHHHHHHSESPKAPVPLLP--PLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEK 417
+P + + K P P P P P P +P PT+P EP + +E
Sbjct: 455 TPKEPS-------PTTTKEPAPTTPKEPAPTTPKKPA----PTTPKEP----APTTPKEP 499
Query: 418 MPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDS 477
P + PKEPA T P TA T +K E+ + P P E +
Sbjct: 500 APTTTKKPAPTTPKEPAPTTPK-ETAPTTPKKLTPT-TPEKLAPTTPEKPAPTTPEELAP 557
Query: 478 RTP 480
TP
Sbjct: 558 TTP 560
Score = 41.6 bits (96), Expect = 0.002
Identities = 52/200 (26%), Positives = 73/200 (36%), Gaps = 18/200 (9%)
Query: 297 QETVLPIKKRKTRETVSIEVKEVVKP-LLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRS 355
+ET L + K T +E KE ST G++ K +S + S +
Sbjct: 179 KETSLTVNKETT-----VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 233
Query: 356 SSASSPPKKEHHHHHHHSESPKAPVPLLPPLP----PPPPEPESSED-PTSPPEPQDL-- 408
A PK E +PK P P P P P P P + + PT+P EP
Sbjct: 234 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 293
Query: 409 -SSSVCKEEKMPRGGSLESDGCPKEPAKT---QPAVATAATAAEKYKHRGEGERKDIVSS 464
S+ +E P + PKEPA T +PA T +A K K +
Sbjct: 294 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 353
Query: 465 SMPRPNREEPVDSRTPVTER 484
+ P P + TP T +
Sbjct: 354 TPKEPAPTTPKEP-TPTTPK 372
Score = 38.9 bits (89), Expect = 0.011
Identities = 70/306 (22%), Positives = 111/306 (36%), Gaps = 38/306 (12%)
Query: 164 SPSRREQKPPKKPKSPK----APGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGK 219
+P+ ++ P PK P AP T +G + TT K A + + K P
Sbjct: 689 APTTLKEPAPTTPKKPAPKELAPTTTKGP-----TSTTSDKPAPTTPKETAPTTPKEPAP 743
Query: 220 LLVKMPF----QTSPGGKAEGGGATTSTQVMVI-KRPGRKR---KAEADPQAI---PKKR 268
K P +T P +E TT+ + I K P AE P+A+ PK+
Sbjct: 744 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 803
Query: 269 GRKPGSVVAAAAAE---AKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLV 325
G AA E K E +R+ ET K T+ET + K +
Sbjct: 804 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM-TKETATTTEKTTESKITA 862
Query: 326 STLGEKSGKGLKTC--KSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLL 383
+T S T K K+ +PK +++ + E + + PK
Sbjct: 863 TTTQVTSTTTQDTTPFKITTLKTTTLAPKV-TTTKKTITTTEIMNKPEETAKPKDRATNS 921
Query: 384 PPLPPPPPEP-ESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVAT 442
P P +P ++ + PTS +P + MPR ++ P++ T P +
Sbjct: 922 KATTPKPQKPTKAPKKPTSTKKP----------KTMPRVRKPKTTPTPRKMTSTMPELNP 971
Query: 443 AATAAE 448
+ AE
Sbjct: 972 TSRIAE 977
Score = 29.3 bits (64), Expect = 8.4
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 11/81 (13%)
Query: 167 RREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQ-VKRVLE----------K 215
++ K PKKP S K P T +PK + T R +T + R+ E +
Sbjct: 929 QKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQ 988
Query: 216 SPGKLLVKMPFQTSPGGKAEG 236
+P LV++ ++ G AEG
Sbjct: 989 TPNSKLVEVNPKSEDAGGAEG 1009
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 52.0 bits (123), Expect = 1e-06
Identities = 107/483 (22%), Positives = 153/483 (31%), Gaps = 60/483 (12%)
Query: 30 KVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIR 89
KVK +KK + K P P + + G + + S + S SPK I
Sbjct: 158 KVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPK-----IT 212
Query: 90 DRGPMYDDPTLPEGWTRKLKQR---KSGRSAGKYDVYLINPQ----GKAFRSKVELIAYF 142
P+ P+LP + + + N Q GK + +
Sbjct: 213 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 272
Query: 143 EKVGDTSLDPND---------FDFTVTGRGSPSRREQKP--PKKPKS--PKAPGTGRGRG 189
EK L P + T G + +E P PK+P S PK P +
Sbjct: 273 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 332
Query: 190 RPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKA-----EGGGATTSTQ 244
P T PK + K P K P T+P A E TT +
Sbjct: 333 AP-----TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 387
Query: 245 VMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIK 304
K P + P PK+ + KE + + +E
Sbjct: 388 PTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 446
Query: 305 KRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLK-----TCKSPGRKSKESSPKGRSSSAS 359
K+ T K +T E S K T KS +KE +P S+ +
Sbjct: 447 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 506
Query: 360 SPPKKEHHHHHHHSESPKAPVPLLP--PLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEK 417
+P + + K P P P P P P +P PT+P EP + +E
Sbjct: 507 TPKEPS-------PTTTKEPAPTTPKEPAPTTPKKPA----PTTPKEP----APTTPKEP 551
Query: 418 MPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDS 477
P + PKEPA T P TA T +K E+ + P P E +
Sbjct: 552 APTTTKKPAPTTPKEPAPTTPK-ETAPTTPKKLTPT-TPEKLAPTTPEKPAPTTPEELAP 609
Query: 478 RTP 480
TP
Sbjct: 610 TTP 612
Score = 52.0 bits (123), Expect = 1e-06
Identities = 70/309 (22%), Positives = 109/309 (35%), Gaps = 30/309 (9%)
Query: 148 TSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAAT-SEG 206
T P T + +P+ E+ P P+ P P T P+ T PKAA +
Sbjct: 584 TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP-TPTT------PEEPAPTTPKAAAPNTP 636
Query: 207 VQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPK 266
+ K P K P T+P K T +K P + P+ +
Sbjct: 637 KEPAPTTPKEPAPTTPKEPAPTTP--KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 694
Query: 267 KRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVS 326
++P S A K ++ + T K T +K +
Sbjct: 695 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT---PKEPAPTTPKGTAPTTLKEPAPT 751
Query: 327 TLGEKSGKGLKTCKSPGRKSKES---SPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLL 383
T + + K L + G S S +P +A + PK+ +PK P P
Sbjct: 752 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA------PTTPKKPAPTT 805
Query: 384 PPLPPPPPE----PESSEDPTSPPEPQDLSSSVCKEEKMPRG--GSLESDGCP--KEPAK 435
P PPP P ++++PT+ + D S+ E P+ S + G P K PA
Sbjct: 806 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 865
Query: 436 TQPAVATAA 444
T+P + T A
Sbjct: 866 TKPEMTTTA 874
Score = 51.2 bits (121), Expect = 2e-06
Identities = 75/298 (25%), Positives = 96/298 (32%), Gaps = 35/298 (11%)
Query: 160 TGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGK 219
T + +P+ ++ P PK P AP T PK T PK T + K P
Sbjct: 383 TTKSAPTTPKEPAPTTPKKP-APTT------PKEPAPTTPKEPTPTTPKEPAPTTKEPAP 435
Query: 220 LLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADP----QAIPKKRGRKPGSV 275
K P T+P K K P E P + P P +
Sbjct: 436 TTPKEPAPTAP--KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 493
Query: 276 VAAAAAEAKKKAV--KESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSG 333
A K KE S + +E K T K +T E +
Sbjct: 494 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 553
Query: 334 KGLKTCKSPGRKS-KESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLP--PPP 390
T K P + KE +P +A + PKK +P P L P P P P
Sbjct: 554 T---TTKKPAPTTPKEPAPTTPKETAPTTPKKL---------TPTTPEKLAPTTPEKPAP 601
Query: 391 PEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAE 448
PE PT+P EP + EE P + PKEPA T P T E
Sbjct: 602 TTPEELA-PTTPEEP----TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 654
Score = 41.6 bits (96), Expect = 0.002
Identities = 52/200 (26%), Positives = 73/200 (36%), Gaps = 18/200 (9%)
Query: 297 QETVLPIKKRKTRETVSIEVKEVVKP-LLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRS 355
+ET L + K T +E KE ST G++ K +S + S +
Sbjct: 231 KETSLTVNKETT-----VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 285
Query: 356 SSASSPPKKEHHHHHHHSESPKAPVPLLPPLP----PPPPEPESSED-PTSPPEPQDL-- 408
A PK E +PK P P P P P P P + + PT+P EP
Sbjct: 286 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 345
Query: 409 -SSSVCKEEKMPRGGSLESDGCPKEPAKT---QPAVATAATAAEKYKHRGEGERKDIVSS 464
S+ +E P + PKEPA T +PA T +A K K +
Sbjct: 346 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 405
Query: 465 SMPRPNREEPVDSRTPVTER 484
+ P P + TP T +
Sbjct: 406 TPKEPAPTTPKEP-TPTTPK 424
Score = 38.9 bits (89), Expect = 0.011
Identities = 70/306 (22%), Positives = 111/306 (36%), Gaps = 38/306 (12%)
Query: 164 SPSRREQKPPKKPKSPK----APGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGK 219
+P+ ++ P PK P AP T +G + TT K A + + K P
Sbjct: 741 APTTLKEPAPTTPKKPAPKELAPTTTKGP-----TSTTSDKPAPTTPKETAPTTPKEPAP 795
Query: 220 LLVKMPF----QTSPGGKAEGGGATTSTQVMVI-KRPGRKR---KAEADPQAI---PKKR 268
K P +T P +E TT+ + I K P AE P+A+ PK+
Sbjct: 796 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 855
Query: 269 GRKPGSVVAAAAAE---AKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLV 325
G AA E K E +R+ ET K T+ET + K +
Sbjct: 856 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM-TKETATTTEKTTESKITA 914
Query: 326 STLGEKSGKGLKTC--KSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLL 383
+T S T K K+ +PK +++ + E + + PK
Sbjct: 915 TTTQVTSTTTQDTTPFKITTLKTTTLAPKV-TTTKKTITTTEIMNKPEETAKPKDRATNS 973
Query: 384 PPLPPPPPEP-ESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVAT 442
P P +P ++ + PTS +P + MPR ++ P++ T P +
Sbjct: 974 KATTPKPQKPTKAPKKPTSTKKP----------KTMPRVRKPKTTPTPRKMTSTMPELNP 1023
Query: 443 AATAAE 448
+ AE
Sbjct: 1024 TSRIAE 1029
Score = 29.3 bits (64), Expect = 8.4
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 11/81 (13%)
Query: 167 RREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQ-VKRVLE----------K 215
++ K PKKP S K P T +PK + T R +T + R+ E +
Sbjct: 981 QKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQ 1040
Query: 216 SPGKLLVKMPFQTSPGGKAEG 236
+P LV++ ++ G AEG
Sbjct: 1041 TPNSKLVEVNPKSEDAGGAEG 1061
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 52.0 bits (123), Expect = 1e-06
Identities = 107/483 (22%), Positives = 153/483 (31%), Gaps = 60/483 (12%)
Query: 30 KVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIR 89
KVK +KK + K P P + + G + + S + S SPK I
Sbjct: 199 KVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPK-----IT 253
Query: 90 DRGPMYDDPTLPEGWTRKLKQR---KSGRSAGKYDVYLINPQ----GKAFRSKVELIAYF 142
P+ P+LP + + + N Q GK + +
Sbjct: 254 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 313
Query: 143 EKVGDTSLDPND---------FDFTVTGRGSPSRREQKP--PKKPKS--PKAPGTGRGRG 189
EK L P + T G + +E P PK+P S PK P +
Sbjct: 314 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 373
Query: 190 RPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKA-----EGGGATTSTQ 244
P T PK + K P K P T+P A E TT +
Sbjct: 374 AP-----TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 428
Query: 245 VMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIK 304
K P + P PK+ + KE + + +E
Sbjct: 429 PTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 487
Query: 305 KRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLK-----TCKSPGRKSKESSPKGRSSSAS 359
K+ T K +T E S K T KS +KE +P S+ +
Sbjct: 488 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 547
Query: 360 SPPKKEHHHHHHHSESPKAPVPLLP--PLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEK 417
+P + + K P P P P P P +P PT+P EP + +E
Sbjct: 548 TPKEPS-------PTTTKEPAPTTPKEPAPTTPKKPA----PTTPKEP----APTTPKEP 592
Query: 418 MPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDS 477
P + PKEPA T P TA T +K E+ + P P E +
Sbjct: 593 APTTTKKPAPTTPKEPAPTTPK-ETAPTTPKKLTPT-TPEKLAPTTPEKPAPTTPEELAP 650
Query: 478 RTP 480
TP
Sbjct: 651 TTP 653
Score = 52.0 bits (123), Expect = 1e-06
Identities = 70/309 (22%), Positives = 109/309 (35%), Gaps = 30/309 (9%)
Query: 148 TSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAAT-SEG 206
T P T + +P+ E+ P P+ P P T P+ T PKAA +
Sbjct: 625 TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP-TPTT------PEEPAPTTPKAAAPNTP 677
Query: 207 VQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPK 266
+ K P K P T+P K T +K P + P+ +
Sbjct: 678 KEPAPTTPKEPAPTTPKEPAPTTP--KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 735
Query: 267 KRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVS 326
++P S A K ++ + T K T +K +
Sbjct: 736 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT---PKEPAPTTPKGTAPTTLKEPAPT 792
Query: 327 TLGEKSGKGLKTCKSPGRKSKES---SPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLL 383
T + + K L + G S S +P +A + PK+ +PK P P
Sbjct: 793 TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA------PTTPKKPAPTT 846
Query: 384 PPLPPPPPE----PESSEDPTSPPEPQDLSSSVCKEEKMPRG--GSLESDGCP--KEPAK 435
P PPP P ++++PT+ + D S+ E P+ S + G P K PA
Sbjct: 847 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 906
Query: 436 TQPAVATAA 444
T+P + T A
Sbjct: 907 TKPEMTTTA 915
Score = 51.2 bits (121), Expect = 2e-06
Identities = 75/298 (25%), Positives = 96/298 (32%), Gaps = 35/298 (11%)
Query: 160 TGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGK 219
T + +P+ ++ P PK P AP T PK T PK T + K P
Sbjct: 424 TTKSAPTTPKEPAPTTPKKP-APTT------PKEPAPTTPKEPTPTTPKEPAPTTKEPAP 476
Query: 220 LLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADP----QAIPKKRGRKPGSV 275
K P T+P K K P E P + P P +
Sbjct: 477 TTPKEPAPTAP--KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 534
Query: 276 VAAAAAEAKKKAV--KESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSG 333
A K KE S + +E K T K +T E +
Sbjct: 535 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 594
Query: 334 KGLKTCKSPGRKS-KESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLP--PPP 390
T K P + KE +P +A + PKK +P P L P P P P
Sbjct: 595 T---TTKKPAPTTPKEPAPTTPKETAPTTPKKL---------TPTTPEKLAPTTPEKPAP 642
Query: 391 PEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAE 448
PE PT+P EP + EE P + PKEPA T P T E
Sbjct: 643 TTPEELA-PTTPEEP----TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 695
Score = 41.6 bits (96), Expect = 0.002
Identities = 52/200 (26%), Positives = 73/200 (36%), Gaps = 18/200 (9%)
Query: 297 QETVLPIKKRKTRETVSIEVKEVVKP-LLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRS 355
+ET L + K T +E KE ST G++ K +S + S +
Sbjct: 272 KETSLTVNKETT-----VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 326
Query: 356 SSASSPPKKEHHHHHHHSESPKAPVPLLPPLP----PPPPEPESSED-PTSPPEPQDL-- 408
A PK E +PK P P P P P P P + + PT+P EP
Sbjct: 327 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 386
Query: 409 -SSSVCKEEKMPRGGSLESDGCPKEPAKT---QPAVATAATAAEKYKHRGEGERKDIVSS 464
S+ +E P + PKEPA T +PA T +A K K +
Sbjct: 387 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 446
Query: 465 SMPRPNREEPVDSRTPVTER 484
+ P P + TP T +
Sbjct: 447 TPKEPAPTTPKEP-TPTTPK 465
Score = 38.9 bits (89), Expect = 0.011
Identities = 70/306 (22%), Positives = 111/306 (36%), Gaps = 38/306 (12%)
Query: 164 SPSRREQKPPKKPKSPK----APGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGK 219
+P+ ++ P PK P AP T +G + TT K A + + K P
Sbjct: 782 APTTLKEPAPTTPKKPAPKELAPTTTKGP-----TSTTSDKPAPTTPKETAPTTPKEPAP 836
Query: 220 LLVKMPF----QTSPGGKAEGGGATTSTQVMVI-KRPGRKR---KAEADPQAI---PKKR 268
K P +T P +E TT+ + I K P AE P+A+ PK+
Sbjct: 837 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 896
Query: 269 GRKPGSVVAAAAAE---AKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLV 325
G AA E K E +R+ ET K T+ET + K +
Sbjct: 897 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM-TKETATTTEKTTESKITA 955
Query: 326 STLGEKSGKGLKTC--KSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLL 383
+T S T K K+ +PK +++ + E + + PK
Sbjct: 956 TTTQVTSTTTQDTTPFKITTLKTTTLAPKV-TTTKKTITTTEIMNKPEETAKPKDRATNS 1014
Query: 384 PPLPPPPPEP-ESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVAT 442
P P +P ++ + PTS +P + MPR ++ P++ T P +
Sbjct: 1015 KATTPKPQKPTKAPKKPTSTKKP----------KTMPRVRKPKTTPTPRKMTSTMPELNP 1064
Query: 443 AATAAE 448
+ AE
Sbjct: 1065 TSRIAE 1070
Score = 29.3 bits (64), Expect = 8.4
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 11/81 (13%)
Query: 167 RREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQ-VKRVLE----------K 215
++ K PKKP S K P T +PK + T R +T + R+ E +
Sbjct: 1022 QKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQ 1081
Query: 216 SPGKLLVKMPFQTSPGGKAEG 236
+P LV++ ++ G AEG
Sbjct: 1082 TPNSKLVEVNPKSEDAGGAEG 1102
>gi|239757043 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 996
Score = 52.0 bits (123), Expect = 1e-06
Identities = 26/73 (35%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 343 GRKSKESSPKGRSSSASSPPKKE----------HHHHHHHSESPKAPVPLLPPLPPPPPE 392
G+ ES K +SA +P + HHHHHHH P +P+ LLPP P P
Sbjct: 629 GKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGS 688
Query: 393 PESSEDPTSPPEP 405
P PP P
Sbjct: 689 ERHHPAPPPPPPP 701
>gi|239751555 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 52.0 bits (123), Expect = 1e-06
Identities = 26/73 (35%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 343 GRKSKESSPKGRSSSASSPPKKE----------HHHHHHHSESPKAPVPLLPPLPPPPPE 392
G+ ES K +SA +P + HHHHHHH P +P+ LLPP P P
Sbjct: 629 GKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGS 688
Query: 393 PESSEDPTSPPEP 405
P PP P
Sbjct: 689 ERHHPAPPPPPPP 701
>gi|239746067 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 52.0 bits (123), Expect = 1e-06
Identities = 26/73 (35%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 343 GRKSKESSPKGRSSSASSPPKKE----------HHHHHHHSESPKAPVPLLPPLPPPPPE 392
G+ ES K +SA +P + HHHHHHH P +P+ LLPP P P
Sbjct: 629 GKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGS 688
Query: 393 PESSEDPTSPPEP 405
P PP P
Sbjct: 689 ERHHPAPPPPPPP 701
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 52.0 bits (123), Expect = 1e-06
Identities = 73/324 (22%), Positives = 108/324 (33%), Gaps = 56/324 (17%)
Query: 165 PSRREQKPPKKPK--SPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLV 222
P +R PP+K + SP A R R RP T PK S Q KS
Sbjct: 374 PPKRTSSPPRKTRRLSPSA-SPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSR----- 427
Query: 223 KMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKK------RGRKPGSVV 276
SPG T V K G +++ P P+K K G +
Sbjct: 428 ---VSVSPG----------RTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMA 474
Query: 277 AAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGL 336
AA + + +++ +++ S + + + ++ EV + +
Sbjct: 475 AADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRR-------RRHSPSR 527
Query: 337 KTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESS 396
SP ++ KE+SP+GR + SPP P P P P
Sbjct: 528 SASPSPRKRQKETSPRGRRRRSPSPPPTRRRRS-----------------PSPAPPPRRR 570
Query: 397 EDPTSPPEPQDLSSSVCKEEKMPRGGS--LESDGCPKEPAKTQPAVATAATAAEKYKHRG 454
PT PP + S + PR S ++ P P K + A + K +
Sbjct: 571 RTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTA---SPPPPPKRRASP 627
Query: 455 EGERKDIVSSSMPRPNREEPVDSR 478
K VS S P R PV R
Sbjct: 628 SPPPKRRVSHSPPPKQRSSPVTKR 651
Score = 43.1 bits (100), Expect = 6e-04
Identities = 52/213 (24%), Positives = 82/213 (38%), Gaps = 32/213 (15%)
Query: 276 VAAAAAEAKKKAVKESSIRSVQETVLPIKKR-KTRETVSIEVKEVVKPLLVSTLGEKSGK 334
+ +A E KK+ +K+ I QE + +KK+ + ++ E KE S +
Sbjct: 119 IPSAFLELKKEEIKQRQIE--QEKLASMKKQDEDKDKRDKEEKE------------SSRE 164
Query: 335 GLKTCKSPGR-KSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEP 393
+ +SP R KS+ SP+ RSS K+ H H ++P P P P
Sbjct: 165 KRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELP 224
Query: 394 ESSEDPTSPPEPQDLSSS----VCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEK 449
E S P + S+S V K E +P PKEP+ + + +
Sbjct: 225 EPSVKVKEPSVQEATSTSDILKVPKPEPIPE---------PKEPSPEKNSKKEKEKEKTR 275
Query: 450 YKHRGEGERKDIVSSSMP---RPNREEPVDSRT 479
+ R + + S P RP R SR+
Sbjct: 276 PRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRS 308
Score = 41.6 bits (96), Expect = 0.002
Identities = 67/297 (22%), Positives = 96/297 (32%), Gaps = 26/297 (8%)
Query: 162 RGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTR---------PKAATSEGVQVKRV 212
R SPSR P+K + +P GR R P T R P+ + +R
Sbjct: 522 RHSPSRSASPSPRKRQKETSP-RGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRR 580
Query: 213 LEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKR---- 268
P + P + SP + + + P KR+A P PK+R
Sbjct: 581 TPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPP--PKRRVSHS 638
Query: 269 ---GRKPGSVVAAAAAEAKKKAVKESS-IRSVQETVLPIKKRKTRETVSIEVKEVVKPLL 324
++ V + K K SS RS +E P ++ + +
Sbjct: 639 PPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPP 698
Query: 325 VSTLGEKSGKGLKTCKSPG-----RKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKA- 378
G S + SP R S+ PK +AS P+ S S
Sbjct: 699 PVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPE 758
Query: 379 PVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAK 435
P PP PP P + +S SP P + S PR E G K+ K
Sbjct: 759 PAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKK 815
Score = 39.3 bits (90), Expect = 0.008
Identities = 102/467 (21%), Positives = 155/467 (33%), Gaps = 61/467 (13%)
Query: 45 PVQPSAHHSAEPAEAGKAETSEGSGSAPAVP--------------EASASPKQRRSIIRD 90
PV+ SA + + + +S S S P P SASP +RR R
Sbjct: 344 PVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRH--RP 401
Query: 91 RGPMYDDPTL-----PEGWTRKLKQRKS---GRSAGKYDVYLINPQGKAFRSKVELIAYF 142
P P P+ R K R S GR++GK + +G R
Sbjct: 402 SPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKH----KGTEKRESPSPAPKP 457
Query: 143 EKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAA 202
KV + S D + S +R Q + +S G+ S RPK +
Sbjct: 458 RKV-ELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSS------SSSEDERPKRS 510
Query: 203 TSEGVQVKRVLEKSPGKLLVKMPF----QTSPGGKAEGGGATTSTQVMVIKRPGRKRKAE 258
+ +V R SP + P +TSP G+ + T+ P +
Sbjct: 511 HVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRR 570
Query: 259 ADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSV---QETVLPIKKRKTRETVSIE 315
P P++R P + + ++ S + T P K R + S
Sbjct: 571 RTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPP 630
Query: 316 VKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSES 375
K V S ++ + +SP SK KG S S S+ + + HS S
Sbjct: 631 PKRRVSH---SPPPKQRSSPVTKRRSPSLSSKHR--KGSSPSRSTREARSPQPNKRHSPS 685
Query: 376 PKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAK 435
P+ P PPP SS SP Q S S ++ R EP K
Sbjct: 686 PRPRAPQTSSSPPPVRRGASS----SPQRRQSPSPSTRPIRRVSR---------TPEPKK 732
Query: 436 TQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVT 482
+ A + + + + ++ P P PV S++P T
Sbjct: 733 IKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP-PAPPSPVQSQSPST 778
Score = 38.9 bits (89), Expect = 0.011
Identities = 97/465 (20%), Positives = 167/465 (35%), Gaps = 110/465 (23%)
Query: 13 SEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAP 72
S +++ G+ P F ++KK++ ++++ + E + + + K E S+
Sbjct: 111 SAQENIAGI---PSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKE----SSR 163
Query: 73 AVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAF 132
E S SP++R+S R P + P RK +S R K P+ K
Sbjct: 164 EKRERSRSPRRRKS----RSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKK-- 217
Query: 133 RSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPK 192
EL KV + S+ + T T S + KP P+ PK P + + K
Sbjct: 218 EKTPELPEPSVKVKEPSVQ----EATST---SDILKVPKPEPIPE-PKEPSPEKNSKKEK 269
Query: 193 GSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPG 252
TRP++ R KS + + P T P + + S + +RP
Sbjct: 270 EKEKTRPRS---------RSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPR----RRPS 316
Query: 253 RKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETV 312
+R+ P R R P + + ++ P+++R+ R +
Sbjct: 317 PRRR--------PSPRRRTPPRRMPPPPRHRRSRS--------------PVRRRR-RSSA 353
Query: 313 SIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHH 372
S+ S K K K SP RK++ SP ++SPP++ H
Sbjct: 354 SLSGSSSSSSSSRSRSPPK--KPPKRTSSPPRKTRRLSP------SASPPRRRHRPS--- 402
Query: 373 SESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKE 432
PP PPP S P PQ + +
Sbjct: 403 -----------PPATPPPKTRHS-------PTPQQSNRT--------------------- 423
Query: 433 PAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDS 477
K++ +V+ T+ + KH+G +R+ S P+P + E +S
Sbjct: 424 -RKSRVSVSPGRTSGKVTKHKGTEKRES--PSPAPKPRKVELSES 465
Score = 37.7 bits (86), Expect = 0.024
Identities = 66/297 (22%), Positives = 106/297 (35%), Gaps = 49/297 (16%)
Query: 162 RGSPSRREQKPP-KKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKL 220
R SPS R PP ++ SP P R P PK S KR + SP
Sbjct: 588 RRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPP-----PKRRASPSPPPKRRVSHSPPPK 642
Query: 221 LVKMPF--QTSPGGKAE---GGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSV 275
P + SP ++ G + ST+ +P ++ P+A P+ P
Sbjct: 643 QRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA-PQTSSSPPPVR 701
Query: 276 VAAAAAEAKKKAVKESS--IRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSG 333
A+++ ++++ S+ IR V T P K +K V+ V VS E +
Sbjct: 702 RGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAA 761
Query: 334 KGLKTCKSPGRKSKESS--------PKGRSSSAS-SPPK--------------------- 363
K SP + S+ K +S + S SPP+
Sbjct: 762 KKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKK 821
Query: 364 -KEHHHHHHHSE----SPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKE 415
K+H H H + + A + P + E+P + PEP+ + S ++
Sbjct: 822 DKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEAED 878
Score = 37.7 bits (86), Expect = 0.024
Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 3/68 (4%)
Query: 12 KSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKH---EPVQPSAHHSAEPAEAGKAETSEGS 68
++ DQ+ G K K K KK KKDKK +K KH + V +A + PA A T+
Sbjct: 800 RNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQ 859
Query: 69 GSAPAVPE 76
A PE
Sbjct: 860 EEPVAAPE 867
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 50.8 bits (120), Expect = 3e-06
Identities = 98/488 (20%), Positives = 164/488 (33%), Gaps = 78/488 (15%)
Query: 26 LKFKKVKKDKKEEKEGKHEPVQP-----SAHHSAEPAEAGKAETSEGSG----SAPAVPE 76
LK K+ +K+K +E K ++ S + E + GKA+ ++ S S+ E
Sbjct: 123 LKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKE 182
Query: 77 ASASPKQRRSIIRDRGPMYDDPTLPEG-----------------WTRKLKQRKSGRSAGK 119
+ ++ +S +DR + P+ W+ KQ S A
Sbjct: 183 KTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASY 242
Query: 120 YDVYLINPQGKAFRSKVELIAYFEKVGDTSL---------DPNDFDFTVTGRGSPSRREQ 170
Y ++P S + +Y + G TS +P+ + + SRR++
Sbjct: 243 GQDYDLSPSRSHTSSNYD--SYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR 300
Query: 171 KPP----KKPKSPKAPGTGRGR-----GRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLL 221
++ S + G+ GR GR + S K + S R KS +
Sbjct: 301 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP 360
Query: 222 VKMPFQTSPGGKAEGGGATTSTQVMVIKRP---------GRKRKAEADPQAIPKKRGRKP 272
+S K + + + ++ P RK+K A A K G++
Sbjct: 361 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES 420
Query: 273 -GSVVAAAAAEAKKKAVKESSIRS------------------VQETVLPIKKRKTRETVS 313
GS V E K+S + S V T L + + + +T
Sbjct: 421 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK 480
Query: 314 IEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKG-RSSSASSPPKKEHHHHHHH 372
+++ E + LV L +G + K K + +PK +S +PP
Sbjct: 481 VKLDENSEKHLVKDL---KAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPP 537
Query: 373 SESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKE 432
P P PPLPP PP P + P PP S +
Sbjct: 538 PLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSS 597
Query: 433 PAKTQPAV 440
A +QP V
Sbjct: 598 QANSQPPV 605
Score = 32.0 bits (71), Expect = 1.3
Identities = 31/132 (23%), Positives = 53/132 (40%), Gaps = 19/132 (14%)
Query: 283 AKKKAVKESSIRSVQETVLPIKKRKTRETVSI--EVKEVVKPLLVSTLGEKSGKGLKTCK 340
A ++++KE+ V +LP ++ T E S +++ ++ LL + + G
Sbjct: 1174 APEESLKEAPSAPV---ILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAG---SL 1227
Query: 341 SPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPT 400
K S P+G + + P E P PP PPPPP P +
Sbjct: 1228 EENNSDKNSGPQGPRRTPTMP-----------QEEAAEKRPPEPPGPPPPPPPPPLVEGD 1276
Query: 401 SPPEPQDLSSSV 412
PQ+L+ +V
Sbjct: 1277 LSSAPQELNPAV 1288
Score = 30.0 bits (66), Expect = 4.9
Identities = 22/71 (30%), Positives = 28/71 (39%), Gaps = 11/71 (15%)
Query: 350 SPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLS 409
SPK + S P KKE H LL LP PP P P PEP+ ++
Sbjct: 644 SPK--ETLPSKPVKKEKEQRTRH---------LLTDLPLPPELPGGDLSPPDSPEPKAIT 692
Query: 410 SSVCKEEKMPR 420
+K P+
Sbjct: 693 PPQQPYKKRPK 703
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 50.8 bits (120), Expect = 3e-06
Identities = 98/488 (20%), Positives = 164/488 (33%), Gaps = 78/488 (15%)
Query: 26 LKFKKVKKDKKEEKEGKHEPVQP-----SAHHSAEPAEAGKAETSEGSG----SAPAVPE 76
LK K+ +K+K +E K ++ S + E + GKA+ ++ S S+ E
Sbjct: 123 LKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKE 182
Query: 77 ASASPKQRRSIIRDRGPMYDDPTLPEG-----------------WTRKLKQRKSGRSAGK 119
+ ++ +S +DR + P+ W+ KQ S A
Sbjct: 183 KTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASY 242
Query: 120 YDVYLINPQGKAFRSKVELIAYFEKVGDTSL---------DPNDFDFTVTGRGSPSRREQ 170
Y ++P S + +Y + G TS +P+ + + SRR++
Sbjct: 243 GQDYDLSPSRSHTSSNYD--SYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR 300
Query: 171 KPP----KKPKSPKAPGTGRGR-----GRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLL 221
++ S + G+ GR GR + S K + S R KS +
Sbjct: 301 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP 360
Query: 222 VKMPFQTSPGGKAEGGGATTSTQVMVIKRP---------GRKRKAEADPQAIPKKRGRKP 272
+S K + + + ++ P RK+K A A K G++
Sbjct: 361 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES 420
Query: 273 -GSVVAAAAAEAKKKAVKESSIRS------------------VQETVLPIKKRKTRETVS 313
GS V E K+S + S V T L + + + +T
Sbjct: 421 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK 480
Query: 314 IEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKG-RSSSASSPPKKEHHHHHHH 372
+++ E + LV L +G + K K + +PK +S +PP
Sbjct: 481 VKLDENSEKHLVKDL---KAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPP 537
Query: 373 SESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKE 432
P P PPLPP PP P + P PP S +
Sbjct: 538 PLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSS 597
Query: 433 PAKTQPAV 440
A +QP V
Sbjct: 598 QANSQPPV 605
Score = 33.9 bits (76), Expect = 0.34
Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 10/132 (7%)
Query: 283 AKKKAVKESSIRSVQETVLPIKKRKTRETVSI--EVKEVVKPLLVSTLGEKSGKGLKTCK 340
A ++++KE+ V +LP ++ T E S +++ ++ LL + + G
Sbjct: 1174 APEESLKEAPSAPV---ILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAG---SL 1227
Query: 341 SPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPT 400
K S P+G + + P ++ H K P P PPPPP P D +
Sbjct: 1228 EENNSDKNSGPQGPRRTPTMPQEEAAACPPHILPPEKRPPEPPGPPPPPPPPPLVEGDLS 1287
Query: 401 SPPEPQDLSSSV 412
S PQ+L+ +V
Sbjct: 1288 S--APQELNPAV 1297
Score = 30.0 bits (66), Expect = 4.9
Identities = 22/71 (30%), Positives = 28/71 (39%), Gaps = 11/71 (15%)
Query: 350 SPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLS 409
SPK + S P KKE H LL LP PP P P PEP+ ++
Sbjct: 644 SPK--ETLPSKPVKKEKEQRTRH---------LLTDLPLPPELPGGDLSPPDSPEPKAIT 692
Query: 410 SSVCKEEKMPR 420
+K P+
Sbjct: 693 PPQQPYKKRPK 703
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 50.4 bits (119), Expect = 4e-06
Identities = 74/278 (26%), Positives = 104/278 (37%), Gaps = 51/278 (18%)
Query: 167 RREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPF 226
R E+ PP K SP P + GR SGTTRP +G+++ + GK + P
Sbjct: 99 RGERAPPAKNTSP-GPVSSPGRA----SGTTRPGPLGQKGLRISAEETVARGKA-TEAPK 152
Query: 227 QT--SPGGKAEGGGATTSTQVMVIKRPGRKRKAEAD-PQAIPKKRGRKPGSVVAAAAAEA 283
++ S G + + G T T + R R E P+ P R R P E
Sbjct: 153 RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP--------TEG 204
Query: 284 KKKAVKESSIRSVQETVLPIKKRKT-----RETVSIEVKEVVKPLLVSTLGEKSGKGLKT 338
+K+V +S S E ++R + + S + PL S +G T
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG--T 262
Query: 339 CKSPGRKSKESSPKG----RSSSASSPPKKEHHHHHHHSESPKA----------PVP--- 381
++P S + PKG R + P K S SP A PVP
Sbjct: 263 PRAPAHPS-QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321
Query: 382 --------LLPPLPP-PPPEPESSEDPTSPPEPQDLSS 410
LPP PP P P + P++PP Q L S
Sbjct: 322 NAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS 359
Score = 35.8 bits (81), Expect = 0.090
Identities = 25/71 (35%), Positives = 31/71 (43%), Gaps = 4/71 (5%)
Query: 376 PKAPVPLL-PPL---PPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPK 431
P+AP PL PPL P PP P S T PP L ++ + SL K
Sbjct: 724 PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAK 783
Query: 432 EPAKTQPAVAT 442
P + PA+AT
Sbjct: 784 PPPQAPPALAT 794
Score = 31.2 bits (69), Expect = 2.2
Identities = 51/249 (20%), Positives = 78/249 (31%), Gaps = 76/249 (30%)
Query: 162 RGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLL 221
R +PS R + P + P+ + + P + RP A
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA-------------------- 230
Query: 222 VKMPFQTSPGGKAEGGGATTSTQVMVIKRP-GRKRKAEADPQAIPKKRGRKPGSVVAAAA 280
GGG ++RP R + A P + P + G A A
Sbjct: 231 --------------GGG---------LQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 267
Query: 281 AEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCK 340
++ K ++R Q V P +K LG S L T
Sbjct: 268 HPSQPKPKGLQALRPPQ--VTPPRKD-----------------AAPALGPLSSSPLATPS 308
Query: 341 SPGRKSKESSPKGRSSS---ASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSE 397
G K++ P +++ A+ PP S P+PL PP P PP ++
Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPP----------SPPLATPLPLAPPSPSAPPSLQTLP 358
Query: 398 DPTSPPEPQ 406
P + P Q
Sbjct: 359 SPPATPPSQ 367
>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase [Homo sapiens]
Length = 1327
Score = 50.4 bits (119), Expect = 4e-06
Identities = 36/130 (27%), Positives = 48/130 (36%), Gaps = 25/130 (19%)
Query: 363 KKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEK----M 418
+ +HHHHHH + AP PP PPPPP T+P P + + +
Sbjct: 6 RSQHHHHHHQQQLQPAPGASAPPPPPPPPLSPGLAPGTTPASPTASGLAPFASPRHGLAL 65
Query: 419 PRG-GSLESDGCPKEP--------------------AKTQPAVATAATAAEKYKHRGEGE 457
P G GS + P+ P A PAV+T++ A G G
Sbjct: 66 PEGDGSRDPPDRPRSPDPVDGTSCCSTTSTICTVAAAPVVPAVSTSSAAGVAPNPAGSGS 125
Query: 458 RKDIVSSSMP 467
SSS P
Sbjct: 126 NNSPSSSSSP 135
>gi|188536004 zinc finger protein 469 [Homo sapiens]
Length = 3925
Score = 49.7 bits (117), Expect = 6e-06
Identities = 102/446 (22%), Positives = 149/446 (33%), Gaps = 117/446 (26%)
Query: 33 KDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRG 92
+ ++ + G+ P +P + P + AP VP A+A P++ RS R R
Sbjct: 979 RPRRNDGLGERPPPRPRRPRTQAPGSR--------ADPAPRVPRAAALPEETRSSRRRRL 1030
Query: 93 PMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDP 152
P DP RK K R G + GK + I Q R
Sbjct: 1031 PPRKDP-------RKRKAR--GGAWGKELILKIVQQKNRLR------------------- 1062
Query: 153 NDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRV 212
++DF S S +++PP P+ PG RGR +G G R + ++G +
Sbjct: 1063 -EYDF-----ASESEEDEQPP-----PRGPGF-RGR---RGRGEKRKEVELTQGPR---- 1103
Query: 213 LEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKP 272
E P K + + +A G GA + + RPG P P+ RG
Sbjct: 1104 -EDEPQKP------RKAARQEAGGDGAPANPEEPGGSRPG--------PGRSPQARGPSR 1148
Query: 273 GSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRET--------------------- 311
AAA E K S+ +P + ET
Sbjct: 1149 SLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAP 1208
Query: 312 VSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHH 371
S E E ++ + GE SPG E P R + + P +
Sbjct: 1209 DSTEFTEALRSPPAACAGEMGA-------SPGLLIPEQPPPSRHDTGTPKPSGSLANTAP 1261
Query: 372 HSESP--------------KAPVPLLPPLPP--PPPE---PESSEDPTSPPEPQDLSSSV 412
H SP +APV PP P E P ++ T+ P+P LSS +
Sbjct: 1262 HGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKI 1321
Query: 413 CKEEKMPRGGSLESDGCPKEPAKTQP 438
P G + + G P QP
Sbjct: 1322 SSFGCDPAGFNRDPLGVPVAKKGPQP 1347
Score = 32.0 bits (71), Expect = 1.3
Identities = 71/305 (23%), Positives = 96/305 (31%), Gaps = 64/305 (20%)
Query: 164 SPSRREQKP--PKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLL 221
+PS+ + P P+K APG RG G PKA Q SP
Sbjct: 3660 TPSKALKFPVHPRKAVGSLAPGE-LARGTENGMKPATPKAKPGPSSQGSG----SP---- 3710
Query: 222 VKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAA 281
PG K GG G+ + A A P R P A A
Sbjct: 3711 -------RPGTKTGGGSQPQPAS-------GQLQSETATTPAKPSFPSRSPAPERLPARA 3756
Query: 282 EAKK--KAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTC 339
+AK K +E+ + ++ P +K GE S K K
Sbjct: 3757 QAKSCTKGPREAGEQGPHGSLGPKEK-----------------------GESSTKRKKGQ 3793
Query: 340 KSPGRKSKESSPKGRSSSA-SSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSED 398
+S+ GR+ SA PP+ P P P P PPP + +
Sbjct: 3794 VPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAE 3853
Query: 399 PTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGER 458
P L + P+G L P K AV A AE + HR +
Sbjct: 3854 PGHTQRKDRLGKA------FPQGRPL------LRPPKRGTAV-HGAEPAEPHTHRTAEAQ 3900
Query: 459 KDIVS 463
D++S
Sbjct: 3901 SDLLS 3905
Score = 31.2 bits (69), Expect = 2.2
Identities = 57/281 (20%), Positives = 99/281 (35%), Gaps = 37/281 (13%)
Query: 37 EEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYD 96
++ EGK P+ S A P G+ E S S RG +
Sbjct: 3581 QDAEGKRAPLVFSGKRRA-PGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHK 3639
Query: 97 -DPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 155
T P G K R + + K + ++P+ + VG SL P +
Sbjct: 3640 GSATKPAGCQSSSKDRSAASTPSKALKFPVHPR--------------KAVG--SLAPGEL 3683
Query: 156 DFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEK 215
RG+ + + PK P + G+G R K G ++P+ A+ + +Q +
Sbjct: 3684 -----ARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQ-LQSETATTP 3737
Query: 216 SPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRP----GRKRKAEADPQAIPKKRGRK 271
+ + P +A+ T + + P G K K E+ + +K+G+
Sbjct: 3738 AKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTK---RKKGQV 3794
Query: 272 PGSVVAAA------AAEAKKKAVKESSIRSVQETVLPIKKR 306
PG + + A A K + ++ VLP K +
Sbjct: 3795 PGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPK 3835
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.126 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,530,255
Number of Sequences: 37866
Number of extensions: 1582131
Number of successful extensions: 24385
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 588
Number of HSP's successfully gapped in prelim test: 1105
Number of HSP's that attempted gapping in prelim test: 12429
Number of HSP's gapped (non-prelim): 7801
length of query: 486
length of database: 18,247,518
effective HSP length: 106
effective length of query: 380
effective length of database: 14,233,722
effective search space: 5408814360
effective search space used: 5408814360
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.