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Search of human proteins with 13325057
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13325057 solute carrier family 27 (fatty acid transporter),
member 5 [Homo sapiens]
(690 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13325057 solute carrier family 27 (fatty acid transporter), m... 1409 0.0
gi|227499619 solute carrier family 27 (fatty acid transporter), ... 559 e-159
gi|62865631 solute carrier family 27 (fatty acid transporter), m... 497 e-140
gi|13325055 solute carrier family 27 (fatty acid transporter), m... 497 e-140
gi|13236579 solute carrier family 27 member 3 [Homo sapiens] 491 e-139
gi|227499621 solute carrier family 27 (fatty acid transporter), ... 484 e-136
gi|38524616 solute carrier family 27, member 1 [Homo sapiens] 376 e-104
gi|40807357 solute carrier family 27 (fatty acid transporter), m... 372 e-103
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] 87 7e-17
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] 87 7e-17
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] 81 4e-15
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H... 62 1e-09
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [... 59 2e-08
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [... 59 2e-08
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H... 57 6e-08
gi|253970489 acyl-CoA synthetase short-chain family member 2 iso... 57 7e-08
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo... 57 7e-08
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho... 56 1e-07
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H... 55 3e-07
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s... 53 8e-07
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 52 1e-06
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 52 1e-06
gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens] 47 5e-05
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom... 46 1e-04
gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens] 43 0.001
gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo... 43 0.001
gi|42794752 acyl-CoA synthetase long-chain family member 3 [Homo... 43 0.001
gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo... 42 0.002
gi|4758332 acyl-CoA synthetase long-chain family member 4 isofor... 40 0.006
gi|12669909 acyl-CoA synthetase long-chain family member 4 isofo... 40 0.006
>gi|13325057 solute carrier family 27 (fatty acid transporter),
member 5 [Homo sapiens]
Length = 690
Score = 1409 bits (3648), Expect = 0.0
Identities = 690/690 (100%), Positives = 690/690 (100%)
Query: 1 MGVRQQLALLLLLLLLLWGLGQPVWPVAVALTLRWLLGDPTCCVLLGLAMLARPWLGPWV 60
MGVRQQLALLLLLLLLLWGLGQPVWPVAVALTLRWLLGDPTCCVLLGLAMLARPWLGPWV
Sbjct: 1 MGVRQQLALLLLLLLLLWGLGQPVWPVAVALTLRWLLGDPTCCVLLGLAMLARPWLGPWV 60
Query: 61 PHGLSLAAAALALTLLPARLPPGLRWLPADVIFLAKILHLGLKIRGCLSRQPPDTFVDAF 120
PHGLSLAAAALALTLLPARLPPGLRWLPADVIFLAKILHLGLKIRGCLSRQPPDTFVDAF
Sbjct: 61 PHGLSLAAAALALTLLPARLPPGLRWLPADVIFLAKILHLGLKIRGCLSRQPPDTFVDAF 120
Query: 121 ERRARAQPGRALLVWTGPGAGSVTFGELDARACQAAWALKAELGDPASLCAGEPTALLVL 180
ERRARAQPGRALLVWTGPGAGSVTFGELDARACQAAWALKAELGDPASLCAGEPTALLVL
Sbjct: 121 ERRARAQPGRALLVWTGPGAGSVTFGELDARACQAAWALKAELGDPASLCAGEPTALLVL 180
Query: 181 ASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILP 240
ASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILP
Sbjct: 181 ASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILP 240
Query: 241 KLQAENIRCFYLSHTSPTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTG 300
KLQAENIRCFYLSHTSPTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTG
Sbjct: 241 KLQAENIRCFYLSHTSPTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTG 300
Query: 301 LPKPAILTHERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAP 360
LPKPAILTHERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAP
Sbjct: 301 LPKPAILTHERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAP 360
Query: 361 KFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVRLAMGNGLRADVWETFQ 420
KFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVRLAMGNGLRADVWETFQ
Sbjct: 361 KFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVRLAMGNGLRADVWETFQ 420
Query: 421 QRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDN 480
QRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDN
Sbjct: 421 QRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDN 480
Query: 481 QGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMD 540
QGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMD
Sbjct: 481 QGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMD 540
Query: 541 REGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQ 600
REGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQ
Sbjct: 541 REGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQ 600
Query: 601 LAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRLVREGFNVGIVVD 660
LAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRLVREGFNVGIVVD
Sbjct: 601 LAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRLVREGFNVGIVVD 660
Query: 661 PLFVLDNRAQSFRPLTAEMYQAVCEGTWRL 690
PLFVLDNRAQSFRPLTAEMYQAVCEGTWRL
Sbjct: 661 PLFVLDNRAQSFRPLTAEMYQAVCEGTWRL 690
>gi|227499619 solute carrier family 27 (fatty acid transporter),
member 2 isoform 1 [Homo sapiens]
Length = 620
Score = 559 bits (1441), Expect = e-159
Identities = 275/601 (45%), Positives = 401/601 (66%), Gaps = 9/601 (1%)
Query: 90 DVIFLAKILHLGLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELD 149
D+ + K+ +G ++R R+P T + AF +AR P + L++ ++T+ ++D
Sbjct: 29 DIGYFLKVAAVGRRVRSYGKRRPARTILRAFLEKARQTPHKPFLLFRDE---TLTYAQVD 85
Query: 150 ARACQAAWALKAELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAWINPHGR 209
R+ Q A AL LG L G+ ALL+ A + +WLGL KLGC A +N + R
Sbjct: 86 RRSNQVARALHDHLG----LRQGDCVALLMGNEPAY--VWLWLGLVKLGCAMACLNYNIR 139
Query: 210 GMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPTPGVGALGAALD 269
L H GA+VL+V P+L+ ++EEILP L+ +++ +Y+S TS T G+ + +D
Sbjct: 140 AKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSFLDKVD 199
Query: 270 AAPSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLSGATADDV 329
+ P+P R+ +T+ +PAL+IYTSGTTGLPK A++TH+R+ + + +SG ADDV
Sbjct: 200 EVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGLTFVSGLKADDV 259
Query: 330 VYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGELLRYL 389
+Y LP YH L++GI GC+ GAT L KFS S FWDDCR++ VTVI Y+GELLRYL
Sbjct: 260 IYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYL 319
Query: 390 CNIPQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCG 449
CN PQ+P DR H VRLA+GNGLR DVW F +RFG I I+E Y +TEGN+G +NY + G
Sbjct: 320 CNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFMNYARKVG 379
Query: 450 ALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYR 509
A+G+++ L + + ++L+++D+E EPVRD G+C+ V GE GLL+ K+ PF GY
Sbjct: 380 AVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTPFNGYA 439
Query: 510 GPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEG 569
G + +E+K +R+V + GD+Y+N+GD+L +D E F+YF DR+GDTFRWKGENV+T EV
Sbjct: 440 GAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVAD 499
Query: 570 VLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFI 629
+ VDF+Q+VNVYGV VP EG++GMA++++ FDG+KL+QH+ +LP+YA P F+
Sbjct: 500 TVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFL 559
Query: 630 RIQDAMEVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQAVCEGTWR 689
RIQD +E+T TFK K LV EGFN ++ D L+ LD+ A+ + P+T ++Y A+ T +
Sbjct: 560 RIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAKMYVPMTEDIYNAISAKTLK 619
Query: 690 L 690
L
Sbjct: 620 L 620
>gi|62865631 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 497 bits (1280), Expect = e-140
Identities = 259/601 (43%), Positives = 385/601 (64%), Gaps = 11/601 (1%)
Query: 90 DVIFLAKILHLGLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELD 149
D F+ K++ + ++++ R T +D F A+ QP + +++ G T+ ++D
Sbjct: 30 DFWFVLKVVLIIIRLKKYEKRGELVTVLDKFLSHAKRQPRKPFIIYEGD---IYTYQDVD 86
Query: 150 ARACQAAWALKAELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAWINPHGR 209
R+ + A + +SL G+ ALL+ S + +W GLAKLGC A++N + R
Sbjct: 87 KRSSRVAHVFL----NHSSLKKGDTVALLM--SNEPDFVHVWFGLAKLGCVVAFLNTNIR 140
Query: 210 GMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPTPGVGALGAALD 269
L + + + G R LVV DL ++EEILP L +ENI + + + P GV +L L
Sbjct: 141 SNSLLNCIRACGPRALVVGADLLGTVEEILPSL-SENISVWGMKDSVPQ-GVISLKEKLS 198
Query: 270 AAPSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLSGATADDV 329
+P PVP +S L+I+TSGTTGLPK A+++ +VL+ S +L G TA D+
Sbjct: 199 TSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAVLWAFGCTAHDI 258
Query: 330 VYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGELLRYL 389
VY LPLYH ++GI GC++LGATCVL KFS S FW DC+++ VTV Y+GEL RYL
Sbjct: 259 VYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYL 318
Query: 390 CNIPQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCG 449
C ++ ++ H VRLA+GNG+R+DVW F RFG I++ E+Y +TE ++ +NY GR G
Sbjct: 319 CKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIG 378
Query: 450 ALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYR 509
A+G+ + ++LS F+L+++D + EP+R+ QG+CI V GEPGLL+++V ++ PF GY
Sbjct: 379 AIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNPFFGYA 438
Query: 510 GPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEG 569
GP + ++ KL+ +V + GDVY NTGD++ D++ FLYF DR GDTFRWKGENV+T EV
Sbjct: 439 GPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVAD 498
Query: 570 VLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFI 629
V+ +DF+Q+ NVYGV + G EG+ GMA++ L P + D EK+Y+ V +LPAYA P F+
Sbjct: 499 VIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFL 558
Query: 630 RIQDAMEVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQAVCEGTWR 689
RIQ+ ME T TFKL+K +LV +GFN + +PL+ +DN +S+ LT E+Y + G +
Sbjct: 559 RIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGEIK 618
Query: 690 L 690
L
Sbjct: 619 L 619
>gi|13325055 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 497 bits (1280), Expect = e-140
Identities = 259/601 (43%), Positives = 385/601 (64%), Gaps = 11/601 (1%)
Query: 90 DVIFLAKILHLGLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELD 149
D F+ K++ + ++++ R T +D F A+ QP + +++ G T+ ++D
Sbjct: 30 DFWFVLKVVLIIIRLKKYEKRGELVTVLDKFLSHAKRQPRKPFIIYEGD---IYTYQDVD 86
Query: 150 ARACQAAWALKAELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAWINPHGR 209
R+ + A + +SL G+ ALL+ S + +W GLAKLGC A++N + R
Sbjct: 87 KRSSRVAHVFL----NHSSLKKGDTVALLM--SNEPDFVHVWFGLAKLGCVVAFLNTNIR 140
Query: 210 GMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPTPGVGALGAALD 269
L + + + G R LVV DL ++EEILP L +ENI + + + P GV +L L
Sbjct: 141 SNSLLNCIRACGPRALVVGADLLGTVEEILPSL-SENISVWGMKDSVPQ-GVISLKEKLS 198
Query: 270 AAPSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLSGATADDV 329
+P PVP +S L+I+TSGTTGLPK A+++ +VL+ S +L G TA D+
Sbjct: 199 TSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAVLWAFGCTAHDI 258
Query: 330 VYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGELLRYL 389
VY LPLYH ++GI GC++LGATCVL KFS S FW DC+++ VTV Y+GEL RYL
Sbjct: 259 VYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYL 318
Query: 390 CNIPQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCG 449
C ++ ++ H VRLA+GNG+R+DVW F RFG I++ E+Y +TE ++ +NY GR G
Sbjct: 319 CKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIG 378
Query: 450 ALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYR 509
A+G+ + ++LS F+L+++D + EP+R+ QG+CI V GEPGLL+++V ++ PF GY
Sbjct: 379 AIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNPFFGYA 438
Query: 510 GPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEG 569
GP + ++ KL+ +V + GDVY NTGD++ D++ FLYF DR GDTFRWKGENV+T EV
Sbjct: 439 GPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVAD 498
Query: 570 VLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFI 629
V+ +DF+Q+ NVYGV + G EG+ GMA++ L P + D EK+Y+ V +LPAYA P F+
Sbjct: 499 VIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFL 558
Query: 630 RIQDAMEVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQAVCEGTWR 689
RIQ+ ME T TFKL+K +LV +GFN + +PL+ +DN +S+ LT E+Y + G +
Sbjct: 559 RIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGEIK 618
Query: 690 L 690
L
Sbjct: 619 L 619
>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
Length = 730
Score = 491 bits (1265), Expect = e-139
Identities = 289/671 (43%), Positives = 380/671 (56%), Gaps = 51/671 (7%)
Query: 71 LALTLLPARLPPGLRWLPADVIFLAKILHLGLKIR----------------GC------- 107
L L LL L P LRWLPAD+ F + L +R GC
Sbjct: 60 LPLLLLKLHLWPQLRWLPADLAFAVRALCCKRALRARALAAAAADPEGPEGGCSLAWRLA 119
Query: 108 --LSRQPPDTFVDAFERR-----ARAQPGRAL------LVWT-GP-----GAGSVTFGEL 148
++ TF+ RR A + RA L W GP G GS GE
Sbjct: 120 ELAQQRAAHTFLIHGSRRFSYSEAERESNRAARAFLRALGWDWGPDGGDSGEGSAGEGER 179
Query: 149 DAR-ACQAAWALKAEL--GDPASLCAG-----EPTALLVLASQAVPA-LCMWLGLAKLGC 199
A A AA AE GD A+ G P A + L A P L +W GLAK G
Sbjct: 180 AAPGAGDAAAGSGAEFAGGDGAARGGGAAAPLSPGATVALLLPAGPEFLWLWFGLAKAGL 239
Query: 200 PTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPTP 259
TA++ R PL H + S GAR LV+ P+ ESLE LP L+A + + +
Sbjct: 240 RTAFVPTALRRGPLLHCLRSCGARALVLAPEFLESLEPDLPALRAMGLHLWAAGPGTHPA 299
Query: 260 GVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKML 319
G+ L A + A PVP L + + L+I+TSGTTGLPK A ++H ++LQ
Sbjct: 300 GISDLLAEVSAEVDGPVPGYLSSPQSITDTCLYIFTSGTTGLPKAARISHLKILQCQGFY 359
Query: 320 SLSGATADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVI 379
L G +DV+Y LPLYH+ G ++GI+GC+ +GAT VL KFS FW+DC+QH VTV
Sbjct: 360 QLCGVHQEDVIYLALPLYHMSGSLLGIVGCMGIGATVVLKSKFSAGQFWEDCQQHRVTVF 419
Query: 380 LYVGELLRYLCNIPQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNM 439
Y+GEL RYL N P +R H VRLA+G+GLR D WE F +RFGP+++ E YG TEGN+
Sbjct: 420 QYIGELCRYLVNQPPSKAERGHKVRLAVGSGLRPDTWERFVRRFGPLQVLETYGLTEGNV 479
Query: 440 GLVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKV 499
+NY G+ GA+G+ S L + + PF L+++D+ EP+RD QG C+ GEPGLL+ V
Sbjct: 480 ATINYTGQRGAVGRASWLYKHIFPFSLIRYDVTTGEPIRDPQGHCMATSPGEPGLLVAPV 539
Query: 500 VSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKG 559
Q PF+GY G EL++ KL+++V + GDV++NTGD+L D +GFL F DR GDTFRWKG
Sbjct: 540 SQQSPFLGYAGGPELAQGKLLKDVFRPGDVFFNTGDLLVCDDQGFLRFHDRTGDTFRWKG 599
Query: 560 ENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAW 619
ENV+T EV V +DFLQ+VNVYGV VPG EG+ GMAA+ L P D +LY HV
Sbjct: 600 ENVATTEVAEVFEALDFLQEVNVYGVTVPGHEGRAGMAALVLRPPHALDLMQLYTHVSEN 659
Query: 620 LPAYATPHFIRIQDAMEVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEM 679
LP YA P F+R+Q+++ T TFK K R+ EGF+ + DPL+VLD ++ PLT
Sbjct: 660 LPPYARPRFLRLQESLATTETFKQQKVRMANEGFDPSTLSDPLYVLDQAVGAYLPLTTAR 719
Query: 680 YQAVCEGTWRL 690
Y A+ G R+
Sbjct: 720 YSALLAGNLRI 730
>gi|227499621 solute carrier family 27 (fatty acid transporter),
member 2 isoform 2 [Homo sapiens]
Length = 567
Score = 484 bits (1245), Expect = e-136
Identities = 251/601 (41%), Positives = 366/601 (60%), Gaps = 62/601 (10%)
Query: 90 DVIFLAKILHLGLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELD 149
D+ + K+ +G ++R R+P T + AF +AR P + L++ ++T+ ++D
Sbjct: 29 DIGYFLKVAAVGRRVRSYGKRRPARTILRAFLEKARQTPHKPFLLFRDE---TLTYAQVD 85
Query: 150 ARACQAAWALKAELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAWINPHGR 209
R+ Q A AL LG L G+ ALL+ A + +WLGL KLGC A +N + R
Sbjct: 86 RRSNQVARALHDHLG----LRQGDCVALLMGNEPAY--VWLWLGLVKLGCAMACLNYNIR 139
Query: 210 GMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPTPGVGALGAALD 269
L H GA+VL+V P+L+ ++EEILP L+ +++ +Y+S TS T G+ + +D
Sbjct: 140 AKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSFLDKVD 199
Query: 270 AAPSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLSGATADDV 329
+ P+P R+ +T+ +PAL+IYTSGTT
Sbjct: 200 EVSTEPIPESWRSEVTFSTPALYIYTSGTT------------------------------ 229
Query: 330 VYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGELLRYL 389
GAT L KFS S FWDDCR++ VTVI Y+GELLRYL
Sbjct: 230 -----------------------GATLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYL 266
Query: 390 CNIPQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCG 449
CN PQ+P DR H VRLA+GNGLR DVW F +RFG I I+E Y +TEGN+G +NY + G
Sbjct: 267 CNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFMNYARKVG 326
Query: 450 ALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYR 509
A+G+++ L + + ++L+++D+E EPVRD G+C+ V GE GLL+ K+ PF GY
Sbjct: 327 AVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTPFNGYA 386
Query: 510 GPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEG 569
G + +E+K +R+V + GD+Y+N+GD+L +D E F+YF DR+GDTFRWKGENV+T EV
Sbjct: 387 GAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVAD 446
Query: 570 VLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFI 629
+ VDF+Q+VNVYGV VP EG++GMA++++ FDG+KL+QH+ +LP+YA P F+
Sbjct: 447 TVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFL 506
Query: 630 RIQDAMEVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQAVCEGTWR 689
RIQD +E+T TFK K LV EGFN ++ D L+ LD+ A+ + P+T ++Y A+ T +
Sbjct: 507 RIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAKMYVPMTEDIYNAISAKTLK 566
Query: 690 L 690
L
Sbjct: 567 L 567
>gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
Length = 646
Score = 376 bits (965), Expect = e-104
Identities = 256/668 (38%), Positives = 349/668 (52%), Gaps = 39/668 (5%)
Query: 29 VALTLRWLLGDPTCCVLLGLAMLARPWLGPWVPHGLSLAAAALALTLLPARLPPGLRWLP 88
V+L L WLLG P A LG +V G L + AR
Sbjct: 12 VSLALLWLLGLPW-------TWSAAAALGVYVGSG---GWRFLRIVCKTAR--------- 52
Query: 89 ADVIFLAKILHLGLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGEL 148
D+ L+ ++ + L++R ++ T F+ + QP R LV G G TF +L
Sbjct: 53 RDLFGLSVLIRVRLELRR--HQRAGHTIPRIFQAVVQRQPERLALVDAGTGE-CWTFAQL 109
Query: 149 DARACQAAWALKAELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAWINPHG 208
DA + A L +LG G+ A+ + L WLGLAK G A +N +
Sbjct: 110 DAYS-NAVANLFRQLG----FAPGDVVAIFLEGRPEFVGL--WLGLAKAGMEAALLNVNL 162
Query: 209 RGMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPT---PGVGALG 265
R PLA + +SGA+ L+ ++ ++ E+ L I+ F P P L
Sbjct: 163 RREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIK-FCSGDLGPEGILPDTHLLD 221
Query: 266 AALDAAPSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLS-GA 324
L A + P+ G+ R +IYTSGTTGLPK AI+ H R +M+ +
Sbjct: 222 PLLKEASTAPLAQIPSKGMDDR--LFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRM 279
Query: 325 TADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGE 384
A DV+Y LPLYH G ++G+ CL G T VL KFS S FWDDC ++ TV+ Y+GE
Sbjct: 280 QAADVLYDCLPLYHSAGNIIGVGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGE 339
Query: 385 LLRYLCNIPQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNY 444
+ RYL P + +R H VRLA+GNGLR +WE F +RFG +I E YG+TE N + N
Sbjct: 340 ICRYLLKQPVREAERRHRVRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANM 399
Query: 445 VGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQP 504
G+ G+ G S +L + P LV+ + + E +RD QG CIP GEPGLL+ ++ Q P
Sbjct: 400 DGKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDP 459
Query: 505 FVGYRG--PRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENV 562
+ G + +K+ +V GD Y +GDVL MD G++YFRDR GDTFRW+GENV
Sbjct: 460 LRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENV 519
Query: 563 STHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPA 622
ST EVEGVLS++ V VYGV VPG EGK GMAAV P D +YQ ++ L
Sbjct: 520 STTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMAAV-ADPHSLLDPNAIYQELQKVLAP 578
Query: 623 YATPHFIRIQDAMEVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQA 682
YA P F+R+ ++ T TFK+ KTRL REGF+ D LF LD + + PL +Y
Sbjct: 579 YARPIFLRLLPQVDTTGTFKIQKTRLQREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTR 638
Query: 683 VCEGTWRL 690
+C G + L
Sbjct: 639 ICSGAFAL 646
>gi|40807357 solute carrier family 27 (fatty acid transporter),
member 4 [Homo sapiens]
Length = 643
Score = 372 bits (955), Expect = e-103
Identities = 237/601 (39%), Positives = 324/601 (53%), Gaps = 23/601 (3%)
Query: 97 ILHLGLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELDARACQAA 156
+L + K+R CL Q T F R P + L++ G TF +LD + A
Sbjct: 59 LLKVKAKVRQCL--QERRTVPILFASTVRRHPDKTALIFEGTDT-HWTFRQLDEYSSSVA 115
Query: 157 WALKAELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAHS 216
L+A L +G+ A+ + L WLG+AKLG A IN + R L H
Sbjct: 116 NFLQAR-----GLASGDVAAIFMENRNEFVGL--WLGMAKLGVEAALINTNLRRDALLHC 168
Query: 217 VLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSP---TPGVGALGAALDAAPS 273
+ +S AR LV ++ ++ E+ L ++ F P P L L AP
Sbjct: 169 LTTSRARALVFGSEMASAICEVHASLDP-SLSLFCSGSWEPGAVPPSTEHLDPLLKDAPK 227
Query: 274 HPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLS-GATADDVVYT 332
H +P+ G T +IYTSGTTGLPK AI+ H R +M+ ++ +D+VY
Sbjct: 228 H-LPSCPDKGFT--DKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIVYD 284
Query: 333 VLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGELLRYLCNI 392
LPLYH G +VGI CL G T V+ KFS S FWDDC ++ T++ Y+GEL RYL N
Sbjct: 285 CLPLYHSAGNIVGIGQCLLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLLNQ 344
Query: 393 PQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCGALG 452
P + + H VR+A+GNGLR +W F RF ++ E YG+TE N L N+ + GA G
Sbjct: 345 PPREAENQHQVRMALGNGLRQSIWTNFSSRFHIPQVAEFYGATECNCSLGNFDSQVGACG 404
Query: 453 KMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQP---FVGYR 509
S +L + P LV+ + + E +R G CIP GEPG L+ +++ + P F GY
Sbjct: 405 FNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPGQLVGRIIQKDPLRRFDGYL 464
Query: 510 GPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEG 569
+ + +K+ ++V + GD Y TGDVL MD G+LYFRDR GDTFRWKGENVST EVEG
Sbjct: 465 N-QGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEG 523
Query: 570 VLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFI 629
LS++ + V VYGV VPG EG+ GMAAV +P D E+ Q + LP YA P F+
Sbjct: 524 TLSRLLDMADVAVYGVEVPGTEGRAGMAAV-ASPTGNCDLERFAQVLEKELPLYARPIFL 582
Query: 630 RIQDAMEVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQAVCEGTWR 689
R+ + T T+K KT L +EGF+ IV DPLF LD + + PL E Y + G +
Sbjct: 583 RLLPELHKTGTYKFQKTELRKEGFDPAIVKDPLFYLDAQKGRYVPLDQEAYSRIQAGEEK 642
Query: 690 L 690
L
Sbjct: 643 L 643
>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 86.7 bits (213), Expect = 7e-17
Identities = 138/542 (25%), Positives = 214/542 (39%), Gaps = 66/542 (12%)
Query: 141 GSVTFGELDARACQAAWALKAELGDPASLCAG----EPTALLVLASQAVPALCMWLGLAK 196
G T+ EL +R+ + + + G C G E + A+ A + W
Sbjct: 64 GRHTYRELYSRSLRLSQEICRLCG-----CVGGDLREERVSFLCANDASYVVAQWASWMS 118
Query: 197 LGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTS 256
G H L + + S + V++ + E L ++ KL +
Sbjct: 119 GGVAVPLYRKHPAAQ-LEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPL------- 170
Query: 257 PTPGVGALGAALDAAPSHPVPADLRAGITWRSP-ALFIYTSGTTGLPKPAILTHERVLQM 315
TP + A++ PVP WR+ A+ IYTSGTTG PK + TH+ + +
Sbjct: 171 -TPAIYT--GAVEEPAEVPVPEQ-----GWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAV 222
Query: 316 SKMLSLSGA-TADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWD---DC 371
L A T DDV+ VLPL+HV G+V +L L +GATCV+ P+FS W+
Sbjct: 223 VTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSS 282
Query: 372 RQHGVTVILYV----GELLRYLCNIPQQPEDR-------THTVRLAMGN--GLRADVWET 418
+ V + V +L+ Y QP + +RL + L V E
Sbjct: 283 ETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEK 342
Query: 419 FQQRFGPIRIWEVYGSTEGNMG----LVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAA 474
++ G + E YG TE M L V G++G +P VQ + +
Sbjct: 343 WKNITGH-TLLERYGMTEIGMALSGPLTTAVRLPGSVG---------TPLPGVQVRIVSE 392
Query: 475 EPVRDNQGFCIPVGLGEPGLLLTK-VVSQQPFVGYRGP---RELSERKLVRNVRQSGDVY 530
P R+ + I E G +T ++ + RGP RE + + D +
Sbjct: 393 NPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGW 452
Query: 531 YNTGDVLAMDREGFLYFRDRLG-DTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPG 589
+ TGD + ++G + R R D + G VS EVE L + V V G VP
Sbjct: 453 FKTGDTVVF-KDGQYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIG--VPD 509
Query: 590 CE-GKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRL 648
G+ A V L G + +L + R L YA P + + + + K+ K L
Sbjct: 510 MTWGQRVTAVVTLREGHSLSHRELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
Query: 649 VR 650
+R
Sbjct: 570 IR 571
>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 86.7 bits (213), Expect = 7e-17
Identities = 138/542 (25%), Positives = 214/542 (39%), Gaps = 66/542 (12%)
Query: 141 GSVTFGELDARACQAAWALKAELGDPASLCAG----EPTALLVLASQAVPALCMWLGLAK 196
G T+ EL +R+ + + + G C G E + A+ A + W
Sbjct: 64 GRHTYRELYSRSLRLSQEICRLCG-----CVGGDLREERVSFLCANDASYVVAQWASWMS 118
Query: 197 LGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTS 256
G H L + + S + V++ + E L ++ KL +
Sbjct: 119 GGVAVPLYRKHPAAQ-LEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPL------- 170
Query: 257 PTPGVGALGAALDAAPSHPVPADLRAGITWRSP-ALFIYTSGTTGLPKPAILTHERVLQM 315
TP + A++ PVP WR+ A+ IYTSGTTG PK + TH+ + +
Sbjct: 171 -TPAIYT--GAVEEPAEVPVPEQ-----GWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAV 222
Query: 316 SKMLSLSGA-TADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWD---DC 371
L A T DDV+ VLPL+HV G+V +L L +GATCV+ P+FS W+
Sbjct: 223 VTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSS 282
Query: 372 RQHGVTVILYV----GELLRYLCNIPQQPEDR-------THTVRLAMGN--GLRADVWET 418
+ V + V +L+ Y QP + +RL + L V E
Sbjct: 283 ETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEK 342
Query: 419 FQQRFGPIRIWEVYGSTEGNMG----LVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAA 474
++ G + E YG TE M L V G++G +P VQ + +
Sbjct: 343 WKNITGH-TLLERYGMTEIGMALSGPLTTAVRLPGSVG---------TPLPGVQVRIVSE 392
Query: 475 EPVRDNQGFCIPVGLGEPGLLLTK-VVSQQPFVGYRGP---RELSERKLVRNVRQSGDVY 530
P R+ + I E G +T ++ + RGP RE + + D +
Sbjct: 393 NPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGW 452
Query: 531 YNTGDVLAMDREGFLYFRDRLG-DTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPG 589
+ TGD + ++G + R R D + G VS EVE L + V V G VP
Sbjct: 453 FKTGDTVVF-KDGQYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIG--VPD 509
Query: 590 CE-GKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRL 648
G+ A V L G + +L + R L YA P + + + + K+ K L
Sbjct: 510 MTWGQRVTAVVTLREGHSLSHRELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
Query: 649 VR 650
+R
Sbjct: 570 IR 571
>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
Length = 615
Score = 80.9 bits (198), Expect = 4e-15
Identities = 145/637 (22%), Positives = 245/637 (38%), Gaps = 66/637 (10%)
Query: 44 VLLGLAMLARPWLGPWVPHGLSLAAAALALTLLPARLPPGLRWLPADVIFLAKILHLG-- 101
V +G+ L R G G+ A AAL+ + ARL G+R+L + + +G
Sbjct: 3 VYVGMLRLGRLCAGS---SGVLGARAALSRSWQEARLQ-GVRFLSSREVDRMVSTPIGGL 58
Query: 102 LKIRGCLSRQ-PPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELDARACQAAWALK 160
++GC + T E A+ P R LV +TF +L +AA L
Sbjct: 59 SYVQGCTKKHLNSKTVGQCLETTAQRVPEREALVVLHEDV-RLTFAQLKEEVDKAASGLL 117
Query: 161 AELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAHSVLSS 220
+ LC G+ + S A + M L A+ G +NP + M L + +
Sbjct: 118 S-----IGLCKGDRLGMWGPNSYAW--VLMQLATAQAGIILVSVNPAYQAMELEYVLKKV 170
Query: 221 GARVLVVDPDLRES-----LEEILPKLQAENIRCF----------YLSHTSPTPGVGALG 265
G + LV + L++I P+++ +S +P PG L
Sbjct: 171 GCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVISVDAPLPGTLLLD 230
Query: 266 AALDAAPSHPVPADLRAG---ITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLS-- 320
+ A + L+ ++ P +TSGTTG PK A L+H ++ S +L
Sbjct: 231 EVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGATLSHYNIVNNSNILGER 290
Query: 321 --LSGATADDV-VYTVLPLYHVMGLVVGILGCLDLGATCVLA-PKFSTSCFWDDCRQHGV 376
L T + + + PLYH +G V G + CL GAT +LA P F+ + +
Sbjct: 291 LKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATLILASPIFNGKKALEAISRERG 350
Query: 377 TVILYVGELLRYLCNIPQQPEDRTHTVRLAMGNGLRA-----DVWETFQQRFGPIRIWEV 431
T + + +I QP+ ++ + G + ++ + +
Sbjct: 351 TFLYGTPTM---FVDILNQPDFSSYDISTMCGGVIAGSPAPPELIRAIINKINMKDLVVA 407
Query: 432 YGSTEGNMGLVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGE 491
YG+TE + + K + R++ E +MEA + L
Sbjct: 408 YGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAK----------LNT 457
Query: 492 PGLLLTKVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRL 551
PG L + +GY G + +E + D +Y TGDV M+ +GF R
Sbjct: 458 PGELCIR--GYCVMLGYWGEPQKTEEAV------DQDKWYWTGDVATMNEQGFCKIVGRS 509
Query: 552 GDTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEK 611
D GEN+ E+E +Q+V V GV G+ A ++L G+ E+
Sbjct: 510 KDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGV-KDDRMGEEICACIRLKDGEETTVEE 568
Query: 612 LYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRL 648
+ + + + P +I +T + K+ K +L
Sbjct: 569 IKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFKL 605
>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
sapiens]
Length = 577
Score = 62.4 bits (150), Expect = 1e-09
Identities = 92/380 (24%), Positives = 151/380 (39%), Gaps = 50/380 (13%)
Query: 289 PALFIYTSGTTGLPKPAILTHERVLQMSKMLS--LSGATADDVVYTVLPLYHVMGLVVGI 346
P + +TSGTTG PK A +H LQ S S L DV + + ++ + +
Sbjct: 220 PMVIFFTSGTTGFPKMAKHSHGLALQPSFPGSRKLRSLKTSDVSWCLSDSGWIVATIWTL 279
Query: 347 LGCLDLGATCVL--APKFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVR 404
+ G T + P+F T ++ + V + R + +D T
Sbjct: 280 VEPWTAGCTVFIHHLPQFDTKVIIQTLLKYPINHFWGVSSIYRMILQ-----QDFTSIRF 334
Query: 405 LAM------GNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVG---RCGALGKMS 455
A+ G + E +++R G + ++E YG +E + Y G + G +GK +
Sbjct: 335 PALEHCYTGGEVVLPKDQEEWKRRTG-LLLYENYGQSETGLICATYWGMKIKPGFMGKAT 393
Query: 456 CLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGL-GEPGLLLTKVVSQQPFVGYRGPREL 514
P+++ V D++G +P G G+ + V F+ Y G E
Sbjct: 394 ------PPYDV---------QVIDDKGSILPPNTEGNIGIRIKPVRPVSLFMCYEGDPEK 438
Query: 515 SERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQV 574
+ + + GD +YNTGD MD EG++ F R D G + EVE L +
Sbjct: 439 TAKV------ECGD-FYNTGDRGKMDEEGYICFLGRSDDIINASGYRIGPAEVESALVEH 491
Query: 575 DFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEK------LYQHVRAWLPAYATPHF 628
+ + V G P G+V A + L P Q +K L QHV++ Y P
Sbjct: 492 PAVAESAVVGSPDP-IRGEVVKAFIVLTP-QFLSHDKDQLTKELQQHVKSVTAPYKYPRK 549
Query: 629 IRIQDAMEVTSTFKLMKTRL 648
+ + T T K+ + L
Sbjct: 550 VEFVSELPKTITGKIERKEL 569
>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 58.5 bits (140), Expect = 2e-08
Identities = 95/373 (25%), Positives = 152/373 (40%), Gaps = 47/373 (12%)
Query: 294 YTSGTTGLPKPAILTHERVLQMSKM-LSLSGATADDVVYTVLPLYHVMGLVVGILGCLDL 352
+TSGT+GLPK A ++ + +KM +G A D+++T+ ++ ++ +L L
Sbjct: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTL 279
Query: 353 GATCV--LAPKFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVR-LAMGN 409
GA L PKF + + ++ + R L H LA G
Sbjct: 280 GACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGE 339
Query: 410 GLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRC-----GALGKM-SCLLRMLSP 463
L + E ++ + G + I E YG TE GL V + G +G SC
Sbjct: 340 SLLPETLENWRAQTG-LDIREFYGQTE--TGLTCMVSKTMKIKPGYMGTAASC------- 389
Query: 464 FELVQFDMEAAEPVRDNQGFCIPVGL-GEPGLLLTKVVSQQPFVGYRGPRELSERKLVRN 522
+D++ V D++G +P G G+ G+ + + F GY + K N
Sbjct: 390 -----YDVQ----VIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPD----KTAAN 436
Query: 523 VRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVDFLQQVNV 582
+R GD ++ GD D +G+ F R D G + EVE L + + + V
Sbjct: 437 IR--GD-FWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAV 493
Query: 583 YGVCVPGCEGKVGMAAVQLA-------PGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAM 635
P G+V A V LA P Q ++L QHV++ Y P I +
Sbjct: 494 ISSPDP-VRGEVVKAFVILASQFLSHDPEQL--TKELQQHVKSVTAPYKYPRKIEFVLNL 550
Query: 636 EVTSTFKLMKTRL 648
T T K+ +T+L
Sbjct: 551 PKTVTGKIQRTKL 563
>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 58.5 bits (140), Expect = 2e-08
Identities = 95/373 (25%), Positives = 152/373 (40%), Gaps = 47/373 (12%)
Query: 294 YTSGTTGLPKPAILTHERVLQMSKM-LSLSGATADDVVYTVLPLYHVMGLVVGILGCLDL 352
+TSGT+GLPK A ++ + +KM +G A D+++T+ ++ ++ +L L
Sbjct: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTL 279
Query: 353 GATCV--LAPKFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVR-LAMGN 409
GA L PKF + + ++ + R L H LA G
Sbjct: 280 GACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGE 339
Query: 410 GLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRC-----GALGKM-SCLLRMLSP 463
L + E ++ + G + I E YG TE GL V + G +G SC
Sbjct: 340 SLLPETLENWRAQTG-LDIREFYGQTE--TGLTCMVSKTMKIKPGYMGTAASC------- 389
Query: 464 FELVQFDMEAAEPVRDNQGFCIPVGL-GEPGLLLTKVVSQQPFVGYRGPRELSERKLVRN 522
+D++ V D++G +P G G+ G+ + + F GY + K N
Sbjct: 390 -----YDVQ----VIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPD----KTAAN 436
Query: 523 VRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVDFLQQVNV 582
+R GD ++ GD D +G+ F R D G + EVE L + + + V
Sbjct: 437 IR--GD-FWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAV 493
Query: 583 YGVCVPGCEGKVGMAAVQLA-------PGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAM 635
P G+V A V LA P Q ++L QHV++ Y P I +
Sbjct: 494 ISSPDP-VRGEVVKAFVILASQFLSHDPEQL--TKELQQHVKSVTAPYKYPRKIEFVLNL 550
Query: 636 EVTSTFKLMKTRL 648
T T K+ +T+L
Sbjct: 551 PKTVTGKIQRTKL 563
>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
sapiens]
Length = 580
Score = 57.0 bits (136), Expect = 6e-08
Identities = 90/380 (23%), Positives = 156/380 (41%), Gaps = 46/380 (12%)
Query: 287 RSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLSGA-----TADDVVYTVLPLYHVMG 341
+ P +TSGTTG PK A + + +L G + D+++ + V
Sbjct: 221 QEPMTIYFTSGTTGFPKMAQHSQS---SLGIGFTLCGRYWLDLKSSDIIWNMSDTGWVKA 277
Query: 342 LVVGILGCLDLGATCVLAPK---FSTSCFWDDCRQHGVTVILYVGELLRYLCNIP-QQPE 397
+ + GA CV + F T F D + +T + + R L ++ +
Sbjct: 278 AIGSVFSSWLCGA-CVFVHRMAQFDTDTFLDTLTTYPITTLCSPPTVYRMLVQKDLKRYK 336
Query: 398 DRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVG---RCGALGKM 454
++ L G L +V E ++ + G + ++E YG TE M N G + G++GK
Sbjct: 337 FKSLRHCLTGGEPLNPEVLEQWRVQTG-LELYEGYGQTEVGMICANQKGQEIKPGSMGK- 394
Query: 455 SCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPREL 514
++ +D++ + D G +P G + G + ++ +PF + +
Sbjct: 395 ----------GMLPYDVQ----IIDENGNVLPPG--KEGEIALRLKPTRPFCFFSKYVD- 437
Query: 515 SERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQV 574
+ +K +R GD +Y TGD MD +G+ +F R D G + EVE L +
Sbjct: 438 NPQKTAATIR--GD-FYVTGDRGVMDSDGYFWFVGRADDVIISSGYRIGPFEVESAL--I 492
Query: 575 DFLQQVNVYGVCVPG-CEGKVGMAAVQL-APGQTFDGEK----LYQHVRAWLPAYATPHF 628
+ V V P G+V A V L AP ++++ EK L HV+ Y P
Sbjct: 493 EHPAVVESAVVSSPDQIRGEVVKAFVVLAAPFKSYNPEKLTLELQDHVKKSTAPYKYPRK 552
Query: 629 IRIQDAMEVTSTFKLMKTRL 648
+ + T T K+ + L
Sbjct: 553 VEFVQELPKTITGKIKRNVL 572
>gi|253970489 acyl-CoA synthetase short-chain family member 2
isoform 2 [Homo sapiens]
Length = 714
Score = 56.6 bits (135), Expect = 7e-08
Identities = 86/380 (22%), Positives = 143/380 (37%), Gaps = 37/380 (9%)
Query: 289 PALFIYTSGTTGLPKPAILT--HERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLVVGI 346
P +YTSG+TG PK + T + + + A+DV + + + G
Sbjct: 323 PLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVT 382
Query: 347 LGCLDLGATCVLAPKFST----SCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHT 402
G L GAT VL T + W ++ VT +R L +P +
Sbjct: 383 YGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSR 442
Query: 403 VRL----AMGNGLRADVWETFQQRFGPIR--IWEVYGSTEGNMGLVNYVGRCGALGKMSC 456
L +G + + W + + G R I + + TE G M
Sbjct: 443 ASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETG-------------GHMLT 489
Query: 457 LLRMLSPFE--LVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPREL 514
L +P + F P N+ G G +V +QP+ G
Sbjct: 490 PLPGATPMKPGSATFPFFGVAPAILNES-----GEELEGEAEGYLVFKQPWPGIMRTVYG 544
Query: 515 SERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQV 574
+ + + YY TGD D++G+ + R+ D G +ST EVE L +
Sbjct: 545 NHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEH 604
Query: 575 DFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFD---GEKLYQHVRAWLPAYATPHFIRI 631
+ + + V G P +G+ V L G TF E+L + +R + ATP +I+
Sbjct: 605 EAVAEAAVVGHPHP-VKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDYIQN 663
Query: 632 QDAMEVTSTFKLMKTRLVRE 651
+ T + K+M+ R++R+
Sbjct: 664 APGLPKTRSGKIMR-RVLRK 682
>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
1 [Homo sapiens]
Length = 701
Score = 56.6 bits (135), Expect = 7e-08
Identities = 86/380 (22%), Positives = 143/380 (37%), Gaps = 37/380 (9%)
Query: 289 PALFIYTSGTTGLPKPAILT--HERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLVVGI 346
P +YTSG+TG PK + T + + + A+DV + + + G
Sbjct: 310 PLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVT 369
Query: 347 LGCLDLGATCVLAPKFST----SCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHT 402
G L GAT VL T + W ++ VT +R L +P +
Sbjct: 370 YGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSR 429
Query: 403 VRL----AMGNGLRADVWETFQQRFGPIR--IWEVYGSTEGNMGLVNYVGRCGALGKMSC 456
L +G + + W + + G R I + + TE G M
Sbjct: 430 ASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETG-------------GHMLT 476
Query: 457 LLRMLSPFE--LVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPREL 514
L +P + F P N+ G G +V +QP+ G
Sbjct: 477 PLPGATPMKPGSATFPFFGVAPAILNES-----GEELEGEAEGYLVFKQPWPGIMRTVYG 531
Query: 515 SERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQV 574
+ + + YY TGD D++G+ + R+ D G +ST EVE L +
Sbjct: 532 NHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEH 591
Query: 575 DFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFD---GEKLYQHVRAWLPAYATPHFIRI 631
+ + + V G P +G+ V L G TF E+L + +R + ATP +I+
Sbjct: 592 EAVAEAAVVGHPHP-VKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDYIQN 650
Query: 632 QDAMEVTSTFKLMKTRLVRE 651
+ T + K+M+ R++R+
Sbjct: 651 APGLPKTRSGKIMR-RVLRK 669
>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
sapiens]
Length = 579
Score = 55.8 bits (133), Expect = 1e-07
Identities = 87/386 (22%), Positives = 155/386 (40%), Gaps = 59/386 (15%)
Query: 287 RSPALFIYTSGTTGLPKPAILTHER-------VLQMSKMLSLSGATADDVVYTVLPLYHV 339
R P +TSGTTG PK ++ H + V + ++L T D+ + V
Sbjct: 222 RDPLAIYFTSGTTGAPK--MVEHSQSSYGLGFVASGRRWVAL---TESDIFWNTTDTGWV 276
Query: 340 MGLVVGILGCLDLGATCVLA---PKFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQP 396
L +C+ P+ + + +T + V + R L
Sbjct: 277 KA--AWTLFSAWPNGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQ----- 329
Query: 397 EDRTH----TVR--LAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVG---R 447
ED T ++R L G L DV E ++ + G + ++E YG +E + N G +
Sbjct: 330 EDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTG-VELYEGYGQSETVVICANPKGMKIK 388
Query: 448 CGALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVG 507
G++GK S P+++ + D++G +P G E G + ++ +PF
Sbjct: 389 SGSMGKAS------PPYDV---------QIVDDEGNVLPPG--EEGNVAVRIRPTRPFCF 431
Query: 508 YRGPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEV 567
+ + E+ + GD +Y TGD MD++G+ +F R D + EV
Sbjct: 432 FNCYLDNPEKTAAS---EQGD-FYITGDRARMDKDGYFWFMGRNDDVINSSSYRIGPVEV 487
Query: 568 EGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPG-QTFDGE----KLYQHVRAWLPA 622
E L++ + + V P G+V A + L P + D E +L +HV+
Sbjct: 488 ESALAEHPAVLESAVVSSPDP-IRGEVVKAFIVLTPAYSSHDPEALTRELQEHVKRVTAP 546
Query: 623 YATPHFIRIQDAMEVTSTFKLMKTRL 648
Y P + + T + K+ +++L
Sbjct: 547 YKYPRKVAFVSELPKTVSGKIQRSKL 572
>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
sapiens]
Length = 577
Score = 54.7 bits (130), Expect = 3e-07
Identities = 90/373 (24%), Positives = 151/373 (40%), Gaps = 47/373 (12%)
Query: 294 YTSGTTGLPKPAILTHERVLQMSKM-LSLSGATADDVVYTVLPLYHVMGLVVGILGCLDL 352
+TSGT+GLPK A ++ + +KM +G A D+++T+ ++ ++ ++ L
Sbjct: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWAL 279
Query: 353 GATCV--LAPKFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVR-LAMGN 409
GA L PKF + + ++ + R L H + +G
Sbjct: 280 GACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGE 339
Query: 410 GLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRC-----GALGKM-SCLLRMLSP 463
L + E ++ + G + I E YG TE GL V + G +G SC
Sbjct: 340 SLLPETLENWRAQTG-LDIRESYGQTE--TGLTCMVSKTMKIKPGYMGTAASC------- 389
Query: 464 FELVQFDMEAAEPVRDNQGFCIPVGL-GEPGLLLTKVVSQQPFVGYRGPRELSERKLVRN 522
+D++ + D++G +P G G+ G+ + + F GY + K N
Sbjct: 390 -----YDVQ----IIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPD----KTAAN 436
Query: 523 VRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVDFLQQVNV 582
+R GD ++ GD D +G+ F R D G + EVE L + + + V
Sbjct: 437 IR--GD-FWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMEHPAVVETAV 493
Query: 583 YGVCVPGCEGKVGMAAVQLA-------PGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAM 635
P G+V A V LA P Q ++L QHV++ Y P I +
Sbjct: 494 ISSPDP-VRGEVVKAFVVLASQFLSHDPEQL--TKELQQHVKSVTAPYKYPRKIEFVLNL 550
Query: 636 EVTSTFKLMKTRL 648
T T K+ + +L
Sbjct: 551 PKTVTGKIQRAKL 563
>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
sapiens]
Length = 586
Score = 53.1 bits (126), Expect = 8e-07
Identities = 106/456 (23%), Positives = 181/456 (39%), Gaps = 56/456 (12%)
Query: 213 LAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPTPGVGALGAALD-AA 271
+ + + SS A ++ + L +++ + K EN+ + + G G L + A+
Sbjct: 159 ILYRLQSSKANCIITNDVLAPAVDAVASK--CENLHSKLIVSENSREGWGNLKELMKHAS 216
Query: 272 PSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLSGA-----TA 326
SH I A+F +TSGT+G PK TH LS++G T
Sbjct: 217 DSHTCVKTKHNEIM----AIF-FTSGTSGYPKMTAHTHS---SFGLGLSVNGRFWLDLTP 268
Query: 327 DDVVYTVLPLYHVMGLVVGILGCLDLGATCVLA---PKFSTSCFWDDCRQHGVTVILYVG 383
DV++ + GA CV P+F + ++ +TV
Sbjct: 269 SDVMWNTSDTGWAKSAWSSVFSPWIQGA-CVFTHHLPRFEPTSILQTLSKYPITVFCSAP 327
Query: 384 ELLRYLCN---IPQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMG 440
+ R L + + H V + G + DV E ++ + G + I+E YG TE +
Sbjct: 328 TVYRMLVQNDITSYKFKSLKHCV--SAGEPITPDVTEKWRNKTG-LDIYEGYGQTETVLI 384
Query: 441 LVNYVG---RCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLT 497
N+ G + G++GK S FD++ + D G +P G + G +
Sbjct: 385 CGNFKGMKIKPGSMGKPS-----------PAFDVK----IVDVNGNVLPPG--QEGDIGI 427
Query: 498 KVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRW 557
+V+ +PF G + K +R + +Y TGD MD++G+ +F R D
Sbjct: 428 QVLPNRPF-GLFTHYVDNPSKTASTLRGN---FYITGDRGYMDKDGYFWFVARADDVILS 483
Query: 558 KGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPG-QTFDGEKL---- 612
G + EVE L++ + + V P G+V A V L P ++ D E+L
Sbjct: 484 SGYRIGPFEVENALNEHPSVAESAVVSSPDP-IRGEVVKAFVVLNPDYKSHDQEQLIKEI 542
Query: 613 YQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRL 648
+HV+ Y P + + T + K + L
Sbjct: 543 QEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNEL 578
>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 2 [Homo sapiens]
Length = 571
Score = 52.4 bits (124), Expect = 1e-06
Identities = 88/366 (24%), Positives = 143/366 (39%), Gaps = 39/366 (10%)
Query: 294 YTSGTTGLPKPAILTHERVLQMSKM-LSLSGATADDVVYTVLPLYHVMGLVVGILGCLDL 352
+TSGT+GLPK A ++ + +KM +G A D+++T+ ++ ++ +L L
Sbjct: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTL 279
Query: 353 GATCV--LAPKFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVR-LAMGN 409
GA L PKF + + ++ + R L H LA G
Sbjct: 280 GACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGE 339
Query: 410 GLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMSCLLRMLSPFELVQF 469
L + E ++ + G + I E YG TE GL V + + K + S +++
Sbjct: 340 SLLPETLENWRAQTG-LDIREFYGQTE--TGLTCMVSKTMKI-KPGYMGTAASCYDVQVI 395
Query: 470 DMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPRELSERKLVRNVRQSGDV 529
P + GF + L F G+ + + K N+R GD
Sbjct: 396 AFVHGSPRAGDLGFAGTMTLS--------------FCGH----QENPDKTAANIR--GD- 434
Query: 530 YYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPG 589
++ GD D +G+ F R D G + EVE L + + + V P
Sbjct: 435 FWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDP- 493
Query: 590 CEGKVGMAAVQLA-------PGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFK 642
G+V A V LA P Q ++L QHV++ Y P I + T T K
Sbjct: 494 VRGEVVKAFVILASQFLSHDPEQL--TKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGK 551
Query: 643 LMKTRL 648
+ +T+L
Sbjct: 552 IQRTKL 557
>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 1 [Homo sapiens]
Length = 571
Score = 52.4 bits (124), Expect = 1e-06
Identities = 88/366 (24%), Positives = 143/366 (39%), Gaps = 39/366 (10%)
Query: 294 YTSGTTGLPKPAILTHERVLQMSKM-LSLSGATADDVVYTVLPLYHVMGLVVGILGCLDL 352
+TSGT+GLPK A ++ + +KM +G A D+++T+ ++ ++ +L L
Sbjct: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTL 279
Query: 353 GATCV--LAPKFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVR-LAMGN 409
GA L PKF + + ++ + R L H LA G
Sbjct: 280 GACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGE 339
Query: 410 GLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMSCLLRMLSPFELVQF 469
L + E ++ + G + I E YG TE GL V + + K + S +++
Sbjct: 340 SLLPETLENWRAQTG-LDIREFYGQTE--TGLTCMVSKTMKI-KPGYMGTAASCYDVQVI 395
Query: 470 DMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPRELSERKLVRNVRQSGDV 529
P + GF + L F G+ + + K N+R GD
Sbjct: 396 AFVHGSPRAGDLGFAGTMTLS--------------FCGH----QENPDKTAANIR--GD- 434
Query: 530 YYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPG 589
++ GD D +G+ F R D G + EVE L + + + V P
Sbjct: 435 FWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDP- 493
Query: 590 CEGKVGMAAVQLA-------PGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFK 642
G+V A V LA P Q ++L QHV++ Y P I + T T K
Sbjct: 494 VRGEVVKAFVILASQFLSHDPEQL--TKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGK 551
Query: 643 LMKTRL 648
+ +T+L
Sbjct: 552 IQRTKL 557
>gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens]
Length = 1098
Score = 47.4 bits (111), Expect = 5e-05
Identities = 87/369 (23%), Positives = 153/369 (41%), Gaps = 48/369 (13%)
Query: 290 ALFIYTSGTTGLPKPAILTHERVL-QMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILG 348
A ++TSGTTG+PK + H+ ++ + L T +DV++ PL VV I
Sbjct: 193 AYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPS-VVEIFL 251
Query: 349 CLDLGATCVLAP--------KFSTSCFWDDCRQHGVTVILYVGELLRYLCN--IPQQPED 398
L GA+ ++ P K ++ F H VTV+ LLR + I
Sbjct: 252 ALSSGASLLIVPTSVKLLPSKLASVLF----SHHRVTVLQATPTLLRRFGSQLIKSTVLS 307
Query: 399 RTHTVR-LAMGNGL--RADVWETFQQRFGPIRIWEVYGSTE-GNMGLVNYVGRCGALGKM 454
T ++R LA+G V +++ +I+ VYG TE + + + +
Sbjct: 308 ATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPEKTLNSTL 367
Query: 455 SCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPREL 514
C L + F L+ +E VRD GF I G G Q F+G R
Sbjct: 368 KCELPVQLGFPLLGTVVE----VRDTNGFTIQEGSG------------QVFLGGRNRVCF 411
Query: 515 SERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQV 574
+ ++ + TGD + + ++G ++F R + G+ ++ V+ V +
Sbjct: 412 LDDEVTVPL----GTMRATGDFVTV-KDGEIFFLGRKDSQIKRHGKRLNIELVQQVAEE- 465
Query: 575 DFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDA 634
LQQV V E + + A + E +++ ++ +LP++A P + + D+
Sbjct: 466 --LQQVESCAVTWYNQEKLILFMVSKDASVK----EYIFKELQKYLPSHAVPDELVLIDS 519
Query: 635 MEVTSTFKL 643
+ TS K+
Sbjct: 520 LPFTSHGKI 528
>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
sapiens]
Length = 689
Score = 46.2 bits (108), Expect = 1e-04
Identities = 113/568 (19%), Positives = 204/568 (35%), Gaps = 62/568 (10%)
Query: 117 VDAFERRARAQPGRALLVWTGPGAGS---VTFGELDARACQAAWALKAELGDPASLCAGE 173
V+ ++ R P L+W G+ +T+ EL C+ A LK + G+
Sbjct: 112 VNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRH-----GVHRGD 166
Query: 174 PTALLVLASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAHSVLSSGARVLVV-DPDLR 232
A+ + S A+ L A++G I LA + + +V++ + LR
Sbjct: 167 RVAIYMPVSPL--AVAAMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLR 224
Query: 233 ESLEEILPKLQAENIR-CFYLSH------TSPTPGVGALGAALDAAPSHPVPADLRAGIT 285
L K+ E ++ C + H T +G L L+ + P +
Sbjct: 225 GGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPESMG 284
Query: 286 WRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLS--LSGATADDVVYTVLPLYHVMGLV 343
+YTSG+TG+PK + T L + + + D+ V + + G
Sbjct: 285 SEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHS 344
Query: 344 VGILGCLDLGATCVL---APKF-STSCFWDDCRQHGVTVILYVGELLRYLCNIPQ---QP 396
+ G L GAT VL P + + +W+ + + +R L +
Sbjct: 345 YVVYGPLCNGATSVLFESTPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKK 404
Query: 397 EDRTHTVRL-AMGNGLRADVWETFQQRFGPIR--IWEVYGSTE-GNMGLVNYVGRCGALG 452
DR+ L ++G + + WE + G R + + + TE G + + GA
Sbjct: 405 YDRSSLRTLGSVGEPINCEAWEWLHRVVGDSRCTLVDTWWQTETGGICIAPRPSEEGAEI 464
Query: 453 KMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFV-----G 507
+ +R V D + + N + + PG+ T Q FV
Sbjct: 465 LPAMAMRPFFGIVPVLMDEKGSVVEGSNVSGALCISQAWPGMARTIYGDHQRFVDAYFKA 524
Query: 508 YRGPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEV 567
Y G YY TGD G+ R+ D G + T E+
Sbjct: 525 YPG-------------------YYFTGDGAYRTEGGYYQITGRMDDVINISGHRLGTAEI 565
Query: 568 EGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAW----LPAY 623
E ++ + + V G +G+ A + + D + + Q +++ + Y
Sbjct: 566 EDAIADHPAVPESAVIGY-PHDIKGEAAFAFI-VVKDSAGDSDVVVQELKSMVATKIAKY 623
Query: 624 ATPHFIRIQDAMEVTSTFKLMKTRLVRE 651
A P I + + T + K+M+ RL+R+
Sbjct: 624 AVPDEILVVKRLPKTRSGKVMR-RLLRK 650
>gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]
Length = 666
Score = 42.7 bits (99), Expect = 0.001
Identities = 23/72 (31%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Query: 290 ALFIYTSGTTGLPKPAILTHERVLQMSKMLSLSGATAD--DVVYTVLPLYHVMGLVVGIL 347
A+ IYTSGTTG+PK +L+H+ + ++ ++ D + V + LPL H+ ++ I
Sbjct: 225 AVLIYTSGTTGIPKGVMLSHDNITWIAGAVTKDFKLTDKHETVVSYLPLSHIAAQMMDIW 284
Query: 348 GCLDLGATCVLA 359
+ +GA A
Sbjct: 285 VPIKIGALTYFA 296
>gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo
sapiens]
Length = 720
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 19/100 (19%)
Query: 261 VGALGA--ALDAAP-SHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQ--- 314
V ALGA +++ P S P+P+D+ A+ +YTSG+TGLPK +++H ++
Sbjct: 259 VEALGAKASMENQPHSKPLPSDI---------AVIMYTSGSTGLPKGVMISHSNIIAGIT 309
Query: 315 -MSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLG 353
M++ + G +DV LPL HV+ L ++ CL G
Sbjct: 310 GMAERIPELG--EEDVYIGYLPLAHVLELSAELV-CLSHG 346
>gi|42794752 acyl-CoA synthetase long-chain family member 3 [Homo
sapiens]
Length = 720
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 19/100 (19%)
Query: 261 VGALGA--ALDAAP-SHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQ--- 314
V ALGA +++ P S P+P+D+ A+ +YTSG+TGLPK +++H ++
Sbjct: 259 VEALGAKASMENQPHSKPLPSDI---------AVIMYTSGSTGLPKGVMISHSNIIAGIT 309
Query: 315 -MSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLG 353
M++ + G +DV LPL HV+ L ++ CL G
Sbjct: 310 GMAERIPELG--EEDVYIGYLPLAHVLELSAELV-CLSHG 346
>gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo
sapiens]
Length = 698
Score = 42.0 bits (97), Expect = 0.002
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 14/86 (16%)
Query: 264 LGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVL-QMSKMLSLS 322
LG A P P P DL A+ +TSGTTG PK A++TH ++ S + +
Sbjct: 254 LGRANRRKPKPPAPEDL---------AVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKAT 304
Query: 323 GATA----DDVVYTVLPLYHVMGLVV 344
T DD + + LPL H+ VV
Sbjct: 305 ENTVNPCPDDTLISFLPLAHMFERVV 330
>gi|4758332 acyl-CoA synthetase long-chain family member 4 isoform 1
[Homo sapiens]
Length = 670
Score = 40.4 bits (93), Expect = 0.006
Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 12/113 (10%)
Query: 243 QAENIRCFYLSHTSPTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTGLP 302
+AE F + +G+ L PS P P+D+ A+ +YTSG+TG P
Sbjct: 194 KAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDM---------AIVMYTSGSTGRP 244
Query: 303 KPAILTHERVL--QMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLG 353
K ++ H ++ + + G D LPL HV+ L I C G
Sbjct: 245 KGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEI-SCFTYG 296
>gi|12669909 acyl-CoA synthetase long-chain family member 4 isoform
2 [Homo sapiens]
Length = 711
Score = 40.4 bits (93), Expect = 0.006
Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 12/113 (10%)
Query: 243 QAENIRCFYLSHTSPTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTGLP 302
+AE F + +G+ L PS P P+D+ A+ +YTSG+TG P
Sbjct: 235 KAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDM---------AIVMYTSGSTGRP 285
Query: 303 KPAILTHERVL--QMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLG 353
K ++ H ++ + + G D LPL HV+ L I C G
Sbjct: 286 KGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEI-SCFTYG 337
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.140 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,562,040
Number of Sequences: 37866
Number of extensions: 1390535
Number of successful extensions: 4199
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 4116
Number of HSP's gapped (non-prelim): 73
length of query: 690
length of database: 18,247,518
effective HSP length: 109
effective length of query: 581
effective length of database: 14,120,124
effective search space: 8203792044
effective search space used: 8203792044
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.