BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sapiens] (1220 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 2417 0.0 gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 2214 0.0 gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap... 2013 0.0 gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 2003 0.0 gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 1967 0.0 gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 1842 0.0 gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 1807 0.0 gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 1756 0.0 gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 302 1e-81 gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 302 1e-81 gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 302 1e-81 gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 302 1e-81 gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom... 302 1e-81 gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom... 302 1e-81 gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom... 302 1e-81 gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 300 4e-81 gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 300 4e-81 gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 300 4e-81 gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 297 4e-80 gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 285 1e-76 gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [... 285 1e-76 gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H... 283 9e-76 gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [... 283 9e-76 gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] 267 5e-71 gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ... 257 5e-68 gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 247 4e-65 gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ... 241 3e-63 gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 232 2e-60 gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] 232 2e-60 gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi... 232 2e-60 >gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sapiens] Length = 1220 Score = 2417 bits (6264), Expect = 0.0 Identities = 1220/1220 (100%), Positives = 1220/1220 (100%) Query: 1 MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC 60 MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC Sbjct: 1 MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC 60 Query: 61 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV 120 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV Sbjct: 61 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV 120 Query: 121 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 180 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK Sbjct: 121 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 180 Query: 181 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID 240 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID Sbjct: 181 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID 240 Query: 241 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 300 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE Sbjct: 241 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 300 Query: 301 KKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVL 360 KKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVL Sbjct: 301 KKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVL 360 Query: 361 QGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFII 420 QGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFII Sbjct: 361 QGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFII 420 Query: 421 GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT 480 GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT Sbjct: 421 GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT 480 Query: 481 NRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVG 540 NRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVG Sbjct: 481 NRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVG 540 Query: 541 NKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKG 600 NKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKG Sbjct: 541 NKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKG 600 Query: 601 ASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPD 660 ASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPD Sbjct: 601 ASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPD 660 Query: 661 WDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCG 720 WDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCG Sbjct: 661 WDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCG 720 Query: 721 IIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDS 780 IIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDS Sbjct: 721 IIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDS 780 Query: 781 TTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM 840 TTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM Sbjct: 781 TTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM 840 Query: 841 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA 900 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA Sbjct: 841 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA 900 Query: 901 TEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAP 960 TEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAP Sbjct: 901 TEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAP 960 Query: 961 LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVI 1020 LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVI Sbjct: 961 LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVI 1020 Query: 1021 VQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTD 1080 VQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTD Sbjct: 1021 VQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTD 1080 Query: 1081 EELAEGEEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESKTSIHN 1140 EELAEGEEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESKTSIHN Sbjct: 1081 EELAEGEEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESKTSIHN 1140 Query: 1141 FMATPEFLINDYTHNIPLIDDTDVDENEERLRAPPPPSPNQNNNAIDSGIYLTTHVTKSA 1200 FMATPEFLINDYTHNIPLIDDTDVDENEERLRAPPPPSPNQNNNAIDSGIYLTTHVTKSA Sbjct: 1141 FMATPEFLINDYTHNIPLIDDTDVDENEERLRAPPPPSPNQNNNAIDSGIYLTTHVTKSA 1200 Query: 1201 TSSVFSSSPGSPLHSVETSL 1220 TSSVFSSSPGSPLHSVETSL Sbjct: 1201 TSSVFSSSPGSPLHSVETSL 1220 >gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sapiens] Length = 1173 Score = 2214 bits (5736), Expect = 0.0 Identities = 1118/1124 (99%), Positives = 1120/1124 (99%) Query: 1 MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC 60 MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC Sbjct: 1 MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC 60 Query: 61 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV 120 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV Sbjct: 61 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV 120 Query: 121 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 180 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK Sbjct: 121 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 180 Query: 181 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID 240 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID Sbjct: 181 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID 240 Query: 241 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 300 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE Sbjct: 241 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 300 Query: 301 KKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVL 360 KKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVL Sbjct: 301 KKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVL 360 Query: 361 QGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFII 420 QGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFII Sbjct: 361 QGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFII 420 Query: 421 GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT 480 GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT Sbjct: 421 GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT 480 Query: 481 NRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVG 540 NRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVG Sbjct: 481 NRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVG 540 Query: 541 NKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKG 600 NKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKG Sbjct: 541 NKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKG 600 Query: 601 ASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPD 660 ASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPD Sbjct: 601 ASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPD 660 Query: 661 WDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCG 720 WDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCG Sbjct: 661 WDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCG 720 Query: 721 IIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDS 780 IIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDS Sbjct: 721 IIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDS 780 Query: 781 TTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM 840 TTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM Sbjct: 781 TTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM 840 Query: 841 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA 900 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA Sbjct: 841 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA 900 Query: 901 TEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAP 960 TEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAP Sbjct: 901 TEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAP 960 Query: 961 LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVI 1020 LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVI Sbjct: 961 LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVI 1020 Query: 1021 VQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTD 1080 VQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTD Sbjct: 1021 VQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTD 1080 Query: 1081 EELAEGEEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSS 1124 EELAEGEEEIDHAERELRRGQILWFRGLNRIQTQ+ VV F+ S Sbjct: 1081 EELAEGEEEIDHAERELRRGQILWFRGLNRIQTQMEVVSTFKRS 1124 >gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sapiens] Length = 1243 Score = 2013 bits (5216), Expect = 0.0 Identities = 1020/1252 (81%), Positives = 1109/1252 (88%), Gaps = 41/1252 (3%) Query: 1 MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC 60 MGDM NS +F+ K Q+ + G FGCT+ ELR+LMELRG EA+ KI+E YGD +C Sbjct: 1 MGDMTNS--DFYSK-NQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAIC 57 Query: 61 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV 120 RRLKTSP EGL DLEKR+QI+GQNFIPPK+PKTFLQLVWEALQDVTLIILE+AAI+ Sbjct: 58 RRLKTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAII 117 Query: 121 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 180 SLGLSFY PPGE +E C GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK Sbjct: 118 SLGLSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 177 Query: 181 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID 240 QFRGLQSRIEQEQKFTV+R GQ++Q+PVA +VVGDIAQVKYGDLLPADG+ IQ NDLKID Sbjct: 178 QFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKID 237 Query: 241 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 300 ESSLTGESD VRKS DKDPMLLSGTHVMEGSGRM+VTAVGVNSQTGIIFTLLGAGGEEEE Sbjct: 238 ESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEE 297 Query: 301 KKDKKG-------------------------------KQQDGAMESSQTKAKKQDGAVAM 329 KKDKKG K QDG +++SQ+KAK+QDGA AM Sbjct: 298 KKDKKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAM 357 Query: 330 EMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLY 389 EMQPLKSAEGG+ ++R KKA+ KKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLY Sbjct: 358 EMQPLKSAEGGDADDR--KKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLY 415 Query: 390 FVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM 449 F ++TFVV + WL ECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM Sbjct: 416 FTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM 475 Query: 450 KDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKIL 509 KDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQ+Y+GD HYKEIP PS++ K + Sbjct: 476 KDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTM 535 Query: 510 DLLVHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFVLDLKRDFQPVREQIPEDK 569 +LL++AI+INSAYTTKILPPEKEGALPRQVGNKTEC LLGFVLDLK+D++PVR Q+PE+K Sbjct: 536 ELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEK 595 Query: 570 LYKVYTFNSVRKSMSTVIRMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRDD 629 LYKVYTFNSVRKSMSTVI++PD FR++SKGASEI+LKKC ILN GE R FRPRDRD+ Sbjct: 596 LYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDE 655 Query: 630 MVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPE 689 MV+K+IEPMACDGLRTIC+AYRDF + EPDWDNEN+++ +LTCI VVGIEDPVRPEVPE Sbjct: 656 MVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPE 715 Query: 690 AIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQ 749 AIRKCQRAGITVRMVTGDNINTARAIA KCGII PGEDFLCLEGKEFNRRIRNEKGEIEQ Sbjct: 716 AIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQ 775 Query: 750 ERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGF 809 ER+DK+WPKLRVLARSSPTDKHTLVKGIIDST EQRQVVAVTGDGTNDGPALKKADVGF Sbjct: 776 ERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGF 835 Query: 810 AMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFT 869 AMGIAGTDVAKEASDIILTDDNF+SIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFT Sbjct: 836 AMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFT 895 Query: 870 GACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRTMMKNI 929 GACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTE+LLLRKPYGR+KPLISRTMMKNI Sbjct: 896 GACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNI 955 Query: 930 LGHAVYQLAIIFTLLFVGELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARK 989 LGHAVYQLA+IFTLLFVGE F IDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARK Sbjct: 956 LGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARK 1015 Query: 990 IHGERNVFDGIFSNPIFCTIVLGTFGIQIVIVQFGGKPFSCSPLSTEQWLWCLFVGVGEL 1049 IHGERNVFDGIF NPIFCTIVLGTF IQIVIVQFGGKPFSCSPL +QW+WC+F+G+GEL Sbjct: 1016 IHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGEL 1075 Query: 1050 VWGQVIATIPTSQLKCLKEAGHGPGKDEMTDEELAEGEEEIDHAERELRRGQILWFRGLN 1109 VWGQVIATIPTS+LK LKEAG K+E+ +EEL E EEIDHAERELRRGQILWFRGLN Sbjct: 1076 VWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLN 1135 Query: 1110 RIQTQIRVVKAFRSSLYEGLEKPESKTSIHNFMATPEFLINDYTHNIPLIDDTDVDENEE 1169 RIQTQIRVVKAFRSSLYEGLEKPES+TSIHNFMA PEF I D +IPLIDDTD++E+ Sbjct: 1136 RIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAA 1195 Query: 1170 -RLRAPPPPSPNQNNNAIDSGIYLTTHVTKSATSSVFSSSPGSPLHSVETSL 1220 + + PP S N+NN+AIDSGI LTT +KSAT SSSPGSP+HS+ETSL Sbjct: 1196 LKQNSSPPSSLNKNNSAIDSGINLTTDTSKSAT----SSSPGSPIHSLETSL 1243 >gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens] Length = 1198 Score = 2003 bits (5188), Expect = 0.0 Identities = 1012/1221 (82%), Positives = 1096/1221 (89%), Gaps = 24/1221 (1%) Query: 1 MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC 60 MGDM NS +F+ K Q+ + G FGCT+ ELR+LMELRG EA+ KI+E YGD +C Sbjct: 1 MGDMTNS--DFYSK-NQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAIC 57 Query: 61 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV 120 RRLKTSP EGL DLEKR+QI+GQNFIPPK+PKTFLQLVWEALQDVTLIILE+AAI+ Sbjct: 58 RRLKTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAII 117 Query: 121 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 180 SLGLSFY PPGE +E C GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK Sbjct: 118 SLGLSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 177 Query: 181 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID 240 QFRGLQSRIEQEQKFTV+R GQ++Q+PVA +VVGDIAQVKYGDLLPADG+ IQ NDLKID Sbjct: 178 QFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKID 237 Query: 241 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 300 ESSLTGESD VRKS DKDPMLLSGTHVMEGSGRM+VTAVGVNSQTGIIFTLLGAGGEEEE Sbjct: 238 ESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEE 297 Query: 301 KKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVL 360 KKDKK KQQDG A AMEMQPLKSAEGG+ ++R KKA+ KKEKSVL Sbjct: 298 KKDKKAKQQDG--------------AAAMEMQPLKSAEGGDADDR--KKASMHKKEKSVL 341 Query: 361 QGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFII 420 QGKLTKLAVQIGKAGLVMSAITVIILVLYF ++TFVV + WL ECTPVYVQYFVKFFII Sbjct: 342 QGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFII 401 Query: 421 GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT 480 GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT Sbjct: 402 GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT 461 Query: 481 NRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVG 540 NRMTVVQ+Y+GD HYKEIP PS++ K ++LL++AI+INSAYTTKILPPEKEGALPRQVG Sbjct: 462 NRMTVVQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVG 521 Query: 541 NKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKG 600 NKTEC LLGFVLDLK+D++PVR Q+PE+KLYKVYTFNSVRKSMSTVI++PD FR++SKG Sbjct: 522 NKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKG 581 Query: 601 ASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPD 660 ASEI+LKKC ILN GE R FRPRDRD+MV+K+IEPMACDGLRTIC+AYRDF + EPD Sbjct: 582 ASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPD 641 Query: 661 WDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCG 720 WDNEN+++ +LTCI VVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIA KCG Sbjct: 642 WDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCG 701 Query: 721 IIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDS 780 II PGEDFLCLEGKEFNRRIRNEKGEIEQER+DK+WPKLRVLARSSPTDKHTLVKGIIDS Sbjct: 702 IIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDS 761 Query: 781 TTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM 840 T EQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNF+SIVKAVM Sbjct: 762 THTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVM 821 Query: 841 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA 900 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA Sbjct: 822 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA 881 Query: 901 TEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAP 960 TEPPTE+LLLRKPYGR+KPLISRTMMKNILGHAVYQLA+IFTLLFVGE F IDSGRNAP Sbjct: 882 TEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAP 941 Query: 961 LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVI 1020 LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIF NPIFCTIVLGTF IQIVI Sbjct: 942 LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVI 1001 Query: 1021 VQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTD 1080 VQFGGKPFSCSPL +QW+WC+F+G+GELVWGQVIATIPTS+LK LKEAG K+E+ + Sbjct: 1002 VQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPE 1061 Query: 1081 EELAEGEEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESKTSIHN 1140 EEL E EEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPES+TSIHN Sbjct: 1062 EELNEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRTSIHN 1121 Query: 1141 FMATPEFLINDYTHNIPLIDDTDVDENEE-RLRAPPPPSPNQNNNAIDSGIYLTTHVTKS 1199 FMA PEF I D +IPLIDDTD++E+ + + PP S N+NN+AIDSGI LTT +KS Sbjct: 1122 FMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKS 1181 Query: 1200 ATSSVFSSSPGSPLHSVETSL 1220 AT SSSPGSP+HS+ETSL Sbjct: 1182 AT----SSSPGSPIHSLETSL 1198 >gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sapiens] Length = 1220 Score = 1967 bits (5096), Expect = 0.0 Identities = 986/1227 (80%), Positives = 1097/1227 (89%), Gaps = 14/1227 (1%) Query: 1 MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC 60 MGDMAN+S+ + ++ G FG TLAELR LMELR +AL+KI+E+YGDV G+C Sbjct: 1 MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGIC 60 Query: 61 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV 120 +LKTSP EGL+ N DLE+R ++G+NFIPPK+PKTFLQLVWEALQDVTLIILE+AAIV Sbjct: 61 TKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIV 120 Query: 121 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 180 SLGLSFY PP ++ CG VS G E+EGE E GWIEGAAILLSV+CVVLVTAFNDWSKEK Sbjct: 121 SLGLSFYQPPEGDNALCGEVSVG-EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEK 179 Query: 181 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID 240 QFRGLQSRIEQEQKFTVIR GQ++Q+PVA + VGDIAQVKYGDLLPADG+LIQ NDLKID Sbjct: 180 QFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKID 239 Query: 241 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 300 ESSLTGESDHV+KS DKDP+LLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE Sbjct: 240 ESSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 299 Query: 301 KKD-----KKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKK 355 KKD KK K+QDGA+E+ + KAK QDGA AMEMQPLKS EGG+ +E++KKKAN PKK Sbjct: 300 KKDEKKKEKKNKKQDGAIEN-RNKAKAQDGA-AMEMQPLKSEEGGDGDEKDKKKANLPKK 357 Query: 356 EKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFV 415 EKSVLQGKLTKLAVQIGKAGL+MSAITVIILVLYFVI+TF V+ R WLAECTP+Y+QYFV Sbjct: 358 EKSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFV 417 Query: 416 KFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKT 475 KFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKT Sbjct: 418 KFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKT 477 Query: 476 GTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGAL 535 GTLT NRMTVVQ+Y+ + HYK++P P A+ P IL LV IS+N AYT+KILPPEKEG L Sbjct: 478 GTLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGL 537 Query: 536 PRQVGNKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFR 595 PR VGNKTECALLG +LDLKRD+Q VR +IPE+ LYKVYTFNSVRKSMSTV++ DG +R Sbjct: 538 PRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYR 597 Query: 596 LFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSA 655 +FSKGASEI+LKKC IL++NGE + FRPRDRDD+V+ +IEPMA +GLRTIC+A+RDF A Sbjct: 598 IFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPA 657 Query: 656 GQ-EPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARA 714 G+ EP+WDNEN++V LTCIAVVGIEDPVRPEVP+AI+KCQRAGITVRMVTGDNINTARA Sbjct: 658 GEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARA 717 Query: 715 IAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLV 774 IA KCGI+ PGEDFLCLEGK+FNRRIRNEKGEIEQER+DK+WPKLRVLARSSPTDKHTLV Sbjct: 718 IATKCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLV 777 Query: 775 KGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTS 834 KGIIDST +QRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTS Sbjct: 778 KGIIDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTS 837 Query: 835 IVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTF 894 IVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDT Sbjct: 838 IVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTL 897 Query: 895 ASLALATEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDID 954 ASLALATEPPTESLLLRKPYGR+KPLISRTMMKNILGHA YQL ++FTLLF GE FFDID Sbjct: 898 ASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDID 957 Query: 955 SGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTF 1014 SGRNAPLH+PPSEHYTI+FNTFV+MQLFNEINARKIHGERNVF+GIF+N IFCTIVLGTF Sbjct: 958 SGRNAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTF 1017 Query: 1015 GIQIVIVQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPG 1074 +QI+IVQFGGKPFSCS LS EQWLW +F+G+G L+WGQ+I+TIPTS+LK LKEAGHG Sbjct: 1018 VVQIIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQ 1077 Query: 1075 KDEMTDEELAEGEEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPES 1134 K+E+ +EELAE EEIDHAERELRRGQILWFRGLNRIQTQIRVV AFRSSLYEGLEKPES Sbjct: 1078 KEEIPEEELAEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVNAFRSSLYEGLEKPES 1137 Query: 1135 KTSIHNFMATPEFLINDYTHNIPLIDDTDVDENEERLR-APPPPSPNQNNNAIDSGIYLT 1193 ++SIHNFM PEF I D +IPLIDDTD +++ R + PPPSPN+NNNA+DSGI+LT Sbjct: 1138 RSSIHNFMTHPEFRIEDSEPHIPLIDDTDAEDDAPTKRNSSPPPSPNKNNNAVDSGIHLT 1197 Query: 1194 THVTKSATSSVFSSSPGSPLHSVETSL 1220 + KSAT SSSPGSPLHS+ETSL Sbjct: 1198 IEMNKSAT----SSSPGSPLHSLETSL 1220 >gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sapiens] Length = 1176 Score = 1842 bits (4771), Expect = 0.0 Identities = 923/1148 (80%), Positives = 1027/1148 (89%), Gaps = 11/1148 (0%) Query: 1 MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC 60 MGDMAN+S+ + ++ G FG TLAELR LMELR +AL+KI+E+YGDV G+C Sbjct: 1 MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGIC 60 Query: 61 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV 120 +LKTSP EGL+ N DLE+R ++G+NFIPPK+PKTFLQLVWEALQDVTLIILE+AAIV Sbjct: 61 TKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIV 120 Query: 121 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 180 SLGLSFY PP ++ CG VS G E+EGE E GWIEGAAILLSV+CVVLVTAFNDWSKEK Sbjct: 121 SLGLSFYQPPEGDNALCGEVSVG-EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEK 179 Query: 181 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID 240 QFRGLQSRIEQEQKFTVIR GQ++Q+PVA + VGDIAQVKYGDLLPADG+LIQ NDLKID Sbjct: 180 QFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKID 239 Query: 241 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 300 ESSLTGESDHV+KS DKDP+LLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE Sbjct: 240 ESSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 299 Query: 301 KKD-----KKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKK 355 KKD KK K+QDGA+E+ + KAK QDGA AMEMQPLKS EGG+ +E++KKKAN PKK Sbjct: 300 KKDEKKKEKKNKKQDGAIEN-RNKAKAQDGA-AMEMQPLKSEEGGDGDEKDKKKANLPKK 357 Query: 356 EKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFV 415 EKSVLQGKLTKLAVQIGKAGL+MSAITVIILVLYFVI+TF V+ R WLAECTP+Y+QYFV Sbjct: 358 EKSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFV 417 Query: 416 KFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKT 475 KFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKT Sbjct: 418 KFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKT 477 Query: 476 GTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGAL 535 GTLT NRMTVVQ+Y+ + HYK++P P A+ P IL LV IS+N AYT+KILPPEKEG L Sbjct: 478 GTLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGL 537 Query: 536 PRQVGNKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFR 595 PR VGNKTECALLG +LDLKRD+Q VR +IPE+ LYKVYTFNSVRKSMSTV++ DG +R Sbjct: 538 PRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYR 597 Query: 596 LFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSA 655 +FSKGASEI+LKKC IL++NGE + FRPRDRDD+V+ +IEPMA +GLRTIC+A+RDF A Sbjct: 598 IFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPA 657 Query: 656 GQ-EPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARA 714 G+ EP+WDNEN++V LTCIAVVGIEDPVRPEVP+AI+KCQRAGITVRMVTGDNINTARA Sbjct: 658 GEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARA 717 Query: 715 IAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLV 774 IA KCGI+ PGEDFLCLEGK+FNRRIRNEKGEIEQER+DK+WPKLRVLARSSPTDKHTLV Sbjct: 718 IATKCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLV 777 Query: 775 KGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTS 834 KGIIDST +QRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTS Sbjct: 778 KGIIDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTS 837 Query: 835 IVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTF 894 IVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDT Sbjct: 838 IVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTL 897 Query: 895 ASLALATEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDID 954 ASLALATEPPTESLLLRKPYGR+KPLISRTMMKNILGHA YQL ++FTLLF GE FFDID Sbjct: 898 ASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDID 957 Query: 955 SGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTF 1014 SGRNAPLH+PPSEHYTI+FNTFV+MQLFNEINARKIHGERNVF+GIF+N IFCTIVLGTF Sbjct: 958 SGRNAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTF 1017 Query: 1015 GIQIVIVQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPG 1074 +QI+IVQFGGKPFSCS LS EQWLW +F+G+G L+WGQ+I+TIPTS+LK LKEAGHG Sbjct: 1018 VVQIIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQ 1077 Query: 1075 KDEMTDEELAEGEEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFR--SSLYEGLEKP 1132 K+E+ +EELAE EEIDHAERELRRGQILWFRGLNRIQTQ+ VV AF+ SS+ L + Sbjct: 1078 KEEIPEEELAEDVEEIDHAERELRRGQILWFRGLNRIQTQMDVVNAFQSGSSIQGALRRQ 1137 Query: 1133 ESKTSIHN 1140 S S H+ Sbjct: 1138 PSIASQHH 1145 >gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sapiens] Length = 1205 Score = 1807 bits (4681), Expect = 0.0 Identities = 903/1173 (76%), Positives = 1015/1173 (86%), Gaps = 17/1173 (1%) Query: 25 GGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLCRRLKTSPTEGLADNTNDLEKRRQI 84 G FGCT+ ELR LMELR +AL +I YG V LC RLKTSP EGL+ N DLEKRRQ+ Sbjct: 20 GDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQV 79 Query: 85 YGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEACGNVSGGA 144 +G N IPPK+PKTFL+LVWEALQDVTLIILE+AAI+SL LSFY P GEE+E CG V+ Sbjct: 80 FGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTP 139 Query: 145 EDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLL 204 EDE EA+AGWIEGAAIL SVI VVLVTAFNDWSKEKQFRGLQ RIEQEQKF++IRNGQL+ Sbjct: 140 EDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLI 199 Query: 205 QVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSADKDPMLLSG 264 Q+PVA +VVGDIAQVKYGDLLPADG+LIQ NDLKIDESSLTGESDHV+KS DKDPMLLSG Sbjct: 200 QLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSG 259 Query: 265 THVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQD 324 THVMEGSGRMVVTAVGVNSQTGII TLLG ++E +K KKGK+Q + ++ KAK QD Sbjct: 260 THVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQ--GVPENRNKAKTQD 317 Query: 325 GAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVI 384 G VA+E+QPL S EG + EE++KK PKKEKSVLQGKLT+LAVQIGKAGL+MSA+TV Sbjct: 318 G-VALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVF 376 Query: 385 ILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYS 444 IL+LYFVI+ FV+ R WL ECTP+Y+QYFVKFFIIG+TVLVVAVPEGLPLAVTISLAYS Sbjct: 377 ILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYS 436 Query: 445 VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSAL 504 VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLT NRMTVVQ+Y+G HY++IP+P Sbjct: 437 VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVF 496 Query: 505 TPKILDLLVHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFVLDLKRDFQPVREQ 564 PK+LDL+V+ ISINSAYT+KILPPEKEG LPRQVGNKTECALLGFV DLK+D+Q VR + Sbjct: 497 LPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNE 556 Query: 565 IPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRP 624 +PE+KLYKVYTFNSVRKSMSTVIR P+GGFR++SKGASEI+L+KC IL+ GE F+ Sbjct: 557 VPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKN 616 Query: 625 RDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVR 684 +DRDDMVR +IEPMACDGLRTICIAYRDF EP WDNENE++ +LTCIAVVGIEDPVR Sbjct: 617 KDRDDMVRTVIEPMACDGLRTICIAYRDFD-DTEPSWDNENEILTELTCIAVVGIEDPVR 675 Query: 685 PEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEK 744 PEVP+AI KC++AGITVRMVTGDNINTARAIA KCGI+ PG+DFLCLEGKEFNR IRNEK Sbjct: 676 PEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLIRNEK 735 Query: 745 GEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKK 804 GE+EQE+LDK+WPKLRVLARSSPTDKHTLVKGIIDST GE RQVVAVTGDGTNDGPALKK Sbjct: 736 GEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKK 795 Query: 805 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 864 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV Sbjct: 796 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 855 Query: 865 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRT 924 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL R+PYGR+KPLISRT Sbjct: 856 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNKPLISRT 915 Query: 925 MMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNE 984 MMKNILGHA YQL +IF L+F GE FFDIDSGR APLHSPPS+HYTI+FNTFV+MQLFNE Sbjct: 916 MMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNTFVLMQLFNE 975 Query: 985 INARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVIVQFGGKPFSCSPLSTEQWLWCLFV 1044 IN+RKIHGE+NVF GI+ N IFC++VLGTF QI IV+FGGKPFSC+ LS QWLWCLF+ Sbjct: 976 INSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCTSLSLSQWLWCLFI 1035 Query: 1045 GVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTDEELAEGEEEIDHAERELRRGQILW 1104 G+GEL+WGQ I+ IPT LK LKEAGHG K+E+T + AEG +EIDHAE ELRRGQILW Sbjct: 1036 GIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKD--AEGLDEIDHAEMELRRGQILW 1093 Query: 1105 FRGLNRIQTQIRVVKAFRSSLYEGLEKPESKTSIHNFMATPEFLINDYTHNIPLIDDTDV 1164 FRGLNRIQTQI+VVKAF SSL+E ++KP ++ SIH+FM PEF I + PL+D+ + Sbjct: 1094 FRGLNRIQTQIKVVKAFHSSLHESIQKPYNQKSIHSFMTHPEFAIEEELPRTPLLDEEE- 1152 Query: 1165 DENEER----------LRAPPPPSPNQNNNAID 1187 +EN ++ L P N NNNA+D Sbjct: 1153 EENPDKASKFGTRVLLLDGEVTPYANTNNNAVD 1185 >gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sapiens] Length = 1170 Score = 1756 bits (4549), Expect = 0.0 Identities = 872/1099 (79%), Positives = 972/1099 (88%), Gaps = 6/1099 (0%) Query: 25 GGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLCRRLKTSPTEGLADNTNDLEKRRQI 84 G FGCT+ ELR LMELR +AL +I YG V LC RLKTSP EGL+ N DLEKRRQ+ Sbjct: 20 GDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQV 79 Query: 85 YGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEACGNVSGGA 144 +G N IPPK+PKTFL+LVWEALQDVTLIILE+AAI+SL LSFY P GEE+E CG V+ Sbjct: 80 FGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTP 139 Query: 145 EDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLL 204 EDE EA+AGWIEGAAIL SVI VVLVTAFNDWSKEKQFRGLQ RIEQEQKF++IRNGQL+ Sbjct: 140 EDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLI 199 Query: 205 QVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSADKDPMLLSG 264 Q+PVA +VVGDIAQVKYGDLLPADG+LIQ NDLKIDESSLTGESDHV+KS DKDPMLLSG Sbjct: 200 QLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSG 259 Query: 265 THVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQD 324 THVMEGSGRMVVTAVGVNSQTGII TLLG ++E +K KKGK+Q + ++ KAK QD Sbjct: 260 THVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQ--GVPENRNKAKTQD 317 Query: 325 GAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVI 384 G VA+E+QPL S EG + EE++KK PKKEKSVLQGKLT+LAVQIGKAGL+MSA+TV Sbjct: 318 G-VALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVF 376 Query: 385 ILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYS 444 IL+LYFVI+ FV+ R WL ECTP+Y+QYFVKFFIIG+TVLVVAVPEGLPLAVTISLAYS Sbjct: 377 ILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYS 436 Query: 445 VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSAL 504 VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLT NRMTVVQ+Y+G HY++IP+P Sbjct: 437 VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVF 496 Query: 505 TPKILDLLVHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFVLDLKRDFQPVREQ 564 PK+LDL+V+ ISINSAYT+KILPPEKEG LPRQVGNKTECALLGFV DLK+D+Q VR + Sbjct: 497 LPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNE 556 Query: 565 IPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRP 624 +PE+KLYKVYTFNSVRKSMSTVIR P+GGFR++SKGASEI+L+KC IL+ GE F+ Sbjct: 557 VPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKN 616 Query: 625 RDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVR 684 +DRDDMVR +IEPMACDGLRTICIAYRDF EP WDNENE++ +LTCIAVVGIEDPVR Sbjct: 617 KDRDDMVRTVIEPMACDGLRTICIAYRDFD-DTEPSWDNENEILTELTCIAVVGIEDPVR 675 Query: 685 PEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEK 744 PEVP+AI KC++AGITVRMVTGDNINTARAIA KCGI+ PG+DFLCLEGKEFNR IRNEK Sbjct: 676 PEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLIRNEK 735 Query: 745 GEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKK 804 GE+EQE+LDK+WPKLRVLARSSPTDKHTLVKGIIDST GE RQVVAVTGDGTNDGPALKK Sbjct: 736 GEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKK 795 Query: 805 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 864 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV Sbjct: 796 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 855 Query: 865 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRT 924 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL R+PYGR+KPLISRT Sbjct: 856 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNKPLISRT 915 Query: 925 MMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNE 984 MMKNILGHA YQL +IF L+F GE FFDIDSGR APLHSPPS+HYTI+FNTFV+MQLFNE Sbjct: 916 MMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNTFVLMQLFNE 975 Query: 985 INARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVIVQFGGKPFSCSPLSTEQWLWCLFV 1044 IN+RKIHGE+NVF GI+ N IFC++VLGTF QI IV+FGGKPFSC+ LS QWLWCLF+ Sbjct: 976 INSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCTSLSLSQWLWCLFI 1035 Query: 1045 GVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTDEELAEGEEEIDHAERELRRGQILW 1104 G+GEL+WGQ I+ IPT LK LKEAGHG K+E+T + AEG +EIDHAE ELRRGQILW Sbjct: 1036 GIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKD--AEGLDEIDHAEMELRRGQILW 1093 Query: 1105 FRGLNRIQTQIRVVKAFRS 1123 FRGLNRIQTQI V+ F++ Sbjct: 1094 FRGLNRIQTQIDVINTFQT 1112 >gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo sapiens] Length = 999 Score = 302 bits (773), Expect = 1e-81 Identities = 275/912 (30%), Positives = 415/912 (45%), Gaps = 159/912 (17%) Query: 82 RQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEACGNVS 141 R+ YG N +P ++ K+ +LV E +D+ + IL +AA+VS L+++ EE E Sbjct: 33 RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF----EEGE------ 82 Query: 142 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNG 201 E ++E I+L ++ +V + + + E L+ + K VIR+ Sbjct: 83 -------ETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133 Query: 202 Q--LLQVPVAALVVGDIAQVKYGDLLPADGVLIQ--ANDLKIDESSLTGESDHVRK---- 253 + + ++ +V GDI +V GD +PAD LI+ + L++D+S LTGES V K Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193 Query: 254 -------SADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKG 306 + DK ML SGT++ G AVGV TG+ T LG Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGL-HTELG------------- 233 Query: 307 KQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTK 366 K + Q AV E PL Q KL + Sbjct: 234 ------------KIRSQMAAVEPERTPL--------------------------QRKLDE 255 Query: 367 LAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLV 426 Q+ A +S I V + V+ G +WL V +F I V + V Sbjct: 256 FGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA--------VYYFKIAVALAV 304 Query: 427 VAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVV 486 A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLTTN+M+V Sbjct: 305 AAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC 364 Query: 487 QSYL-----------------GDTHYKEIPAPSALTPKI---LDLLVHAISINSAYTTKI 526 + ++ G T+ E P D LV +I + Sbjct: 365 RMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSA 424 Query: 527 LPPEKEGALPRQVGNKTECALLGFVLDLK---RDFQPVRE--------QIPEDKLYKVYT 575 L + + +VG TE AL V + D Q + + + + K +T Sbjct: 425 LDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFT 484 Query: 576 --FNSVRKSMSTVIRM----PDG-GFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRD 628 F+ RKSMS P G G ++F KGA E ++++C+++ P R+ Sbjct: 485 LEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV-RVGSRTAPLTPTSRE 543 Query: 629 DMVRKIIE-PMACDGLRTICIAYRDFSAGQEP----DWDNENEVVGDLTCIAVVGIEDPV 683 ++ KI + D LR + +A RD +E D + DLT + VG+ DP Sbjct: 544 QILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDPP 603 Query: 684 RPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNE 743 RPEV I +C +AGI V M+TGDN TA AI + GI ED + GK + R E Sbjct: 604 RPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTED---VAGKAYTGR---E 657 Query: 744 KGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALK 803 ++ E+ + R AR P K +V+ + ++ A+TGDG ND PALK Sbjct: 658 FDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFN-----EITAMTGDGVNDAPALK 712 Query: 804 KADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVA 863 KA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+++ ++ NV Sbjct: 713 KAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGE 771 Query: 864 VIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISR 923 V+ F A + L VQ+LWVNL+ D + AL PP ++ + P + LIS Sbjct: 772 VVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISG 831 Query: 924 TMMKNILGHAVY 935 + L VY Sbjct: 832 WLFFRYLAIGVY 843 >gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo sapiens] Length = 1029 Score = 302 bits (773), Expect = 1e-81 Identities = 275/912 (30%), Positives = 415/912 (45%), Gaps = 159/912 (17%) Query: 82 RQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEACGNVS 141 R+ YG N +P ++ K+ +LV E +D+ + IL +AA+VS L+++ EE E Sbjct: 33 RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF----EEGE------ 82 Query: 142 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNG 201 E ++E I+L ++ +V + + + E L+ + K VIR+ Sbjct: 83 -------ETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133 Query: 202 Q--LLQVPVAALVVGDIAQVKYGDLLPADGVLIQ--ANDLKIDESSLTGESDHVRK---- 253 + + ++ +V GDI +V GD +PAD LI+ + L++D+S LTGES V K Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193 Query: 254 -------SADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKG 306 + DK ML SGT++ G AVGV TG+ T LG Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGL-HTELG------------- 233 Query: 307 KQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTK 366 K + Q AV E PL Q KL + Sbjct: 234 ------------KIRSQMAAVEPERTPL--------------------------QRKLDE 255 Query: 367 LAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLV 426 Q+ A +S I V + V+ G +WL V +F I V + V Sbjct: 256 FGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA--------VYYFKIAVALAV 304 Query: 427 VAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVV 486 A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLTTN+M+V Sbjct: 305 AAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC 364 Query: 487 QSYL-----------------GDTHYKEIPAPSALTPKI---LDLLVHAISINSAYTTKI 526 + ++ G T+ E P D LV +I + Sbjct: 365 RMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSA 424 Query: 527 LPPEKEGALPRQVGNKTECALLGFVLDLK---RDFQPVRE--------QIPEDKLYKVYT 575 L + + +VG TE AL V + D Q + + + + K +T Sbjct: 425 LDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFT 484 Query: 576 --FNSVRKSMSTVIRM----PDG-GFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRD 628 F+ RKSMS P G G ++F KGA E ++++C+++ P R+ Sbjct: 485 LEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV-RVGSRTAPLTPTSRE 543 Query: 629 DMVRKIIE-PMACDGLRTICIAYRDFSAGQEP----DWDNENEVVGDLTCIAVVGIEDPV 683 ++ KI + D LR + +A RD +E D + DLT + VG+ DP Sbjct: 544 QILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDPP 603 Query: 684 RPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNE 743 RPEV I +C +AGI V M+TGDN TA AI + GI ED + GK + R E Sbjct: 604 RPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTED---VAGKAYTGR---E 657 Query: 744 KGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALK 803 ++ E+ + R AR P K +V+ + ++ A+TGDG ND PALK Sbjct: 658 FDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFN-----EITAMTGDGVNDAPALK 712 Query: 804 KADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVA 863 KA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+++ ++ NV Sbjct: 713 KAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGE 771 Query: 864 VIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISR 923 V+ F A + L VQ+LWVNL+ D + AL PP ++ + P + LIS Sbjct: 772 VVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISG 831 Query: 924 TMMKNILGHAVY 935 + L VY Sbjct: 832 WLFFRYLAIGVY 843 >gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo sapiens] Length = 998 Score = 302 bits (773), Expect = 1e-81 Identities = 275/912 (30%), Positives = 415/912 (45%), Gaps = 159/912 (17%) Query: 82 RQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEACGNVS 141 R+ YG N +P ++ K+ +LV E +D+ + IL +AA+VS L+++ EE E Sbjct: 33 RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF----EEGE------ 82 Query: 142 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNG 201 E ++E I+L ++ +V + + + E L+ + K VIR+ Sbjct: 83 -------ETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133 Query: 202 Q--LLQVPVAALVVGDIAQVKYGDLLPADGVLIQ--ANDLKIDESSLTGESDHVRK---- 253 + + ++ +V GDI +V GD +PAD LI+ + L++D+S LTGES V K Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193 Query: 254 -------SADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKG 306 + DK ML SGT++ G AVGV TG+ T LG Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGL-HTELG------------- 233 Query: 307 KQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTK 366 K + Q AV E PL Q KL + Sbjct: 234 ------------KIRSQMAAVEPERTPL--------------------------QRKLDE 255 Query: 367 LAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLV 426 Q+ A +S I V + V+ G +WL V +F I V + V Sbjct: 256 FGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA--------VYYFKIAVALAV 304 Query: 427 VAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVV 486 A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLTTN+M+V Sbjct: 305 AAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC 364 Query: 487 QSYL-----------------GDTHYKEIPAPSALTPKI---LDLLVHAISINSAYTTKI 526 + ++ G T+ E P D LV +I + Sbjct: 365 RMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSA 424 Query: 527 LPPEKEGALPRQVGNKTECALLGFVLDLK---RDFQPVRE--------QIPEDKLYKVYT 575 L + + +VG TE AL V + D Q + + + + K +T Sbjct: 425 LDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFT 484 Query: 576 --FNSVRKSMSTVIRM----PDG-GFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRD 628 F+ RKSMS P G G ++F KGA E ++++C+++ P R+ Sbjct: 485 LEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV-RVGSRTAPLTPTSRE 543 Query: 629 DMVRKIIE-PMACDGLRTICIAYRDFSAGQEP----DWDNENEVVGDLTCIAVVGIEDPV 683 ++ KI + D LR + +A RD +E D + DLT + VG+ DP Sbjct: 544 QILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDPP 603 Query: 684 RPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNE 743 RPEV I +C +AGI V M+TGDN TA AI + GI ED + GK + R E Sbjct: 604 RPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTED---VAGKAYTGR---E 657 Query: 744 KGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALK 803 ++ E+ + R AR P K +V+ + ++ A+TGDG ND PALK Sbjct: 658 FDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFN-----EITAMTGDGVNDAPALK 712 Query: 804 KADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVA 863 KA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+++ ++ NV Sbjct: 713 KAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGE 771 Query: 864 VIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISR 923 V+ F A + L VQ+LWVNL+ D + AL PP ++ + P + LIS Sbjct: 772 VVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISG 831 Query: 924 TMMKNILGHAVY 935 + L VY Sbjct: 832 WLFFRYLAIGVY 843 >gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo sapiens] Length = 1029 Score = 302 bits (773), Expect = 1e-81 Identities = 275/912 (30%), Positives = 415/912 (45%), Gaps = 159/912 (17%) Query: 82 RQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEACGNVS 141 R+ YG N +P ++ K+ +LV E +D+ + IL +AA+VS L+++ EE E Sbjct: 33 RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF----EEGE------ 82 Query: 142 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNG 201 E ++E I+L ++ +V + + + E L+ + K VIR+ Sbjct: 83 -------ETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133 Query: 202 Q--LLQVPVAALVVGDIAQVKYGDLLPADGVLIQ--ANDLKIDESSLTGESDHVRK---- 253 + + ++ +V GDI +V GD +PAD LI+ + L++D+S LTGES V K Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193 Query: 254 -------SADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKG 306 + DK ML SGT++ G AVGV TG+ T LG Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGL-HTELG------------- 233 Query: 307 KQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTK 366 K + Q AV E PL Q KL + Sbjct: 234 ------------KIRSQMAAVEPERTPL--------------------------QRKLDE 255 Query: 367 LAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLV 426 Q+ A +S I V + V+ G +WL V +F I V + V Sbjct: 256 FGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA--------VYYFKIAVALAV 304 Query: 427 VAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVV 486 A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLTTN+M+V Sbjct: 305 AAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC 364 Query: 487 QSYL-----------------GDTHYKEIPAPSALTPKI---LDLLVHAISINSAYTTKI 526 + ++ G T+ E P D LV +I + Sbjct: 365 RMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSA 424 Query: 527 LPPEKEGALPRQVGNKTECALLGFVLDLK---RDFQPVRE--------QIPEDKLYKVYT 575 L + + +VG TE AL V + D Q + + + + K +T Sbjct: 425 LDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFT 484 Query: 576 --FNSVRKSMSTVIRM----PDG-GFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRD 628 F+ RKSMS P G G ++F KGA E ++++C+++ P R+ Sbjct: 485 LEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV-RVGSRTAPLTPTSRE 543 Query: 629 DMVRKIIE-PMACDGLRTICIAYRDFSAGQEP----DWDNENEVVGDLTCIAVVGIEDPV 683 ++ KI + D LR + +A RD +E D + DLT + VG+ DP Sbjct: 544 QILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDPP 603 Query: 684 RPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNE 743 RPEV I +C +AGI V M+TGDN TA AI + GI ED + GK + R E Sbjct: 604 RPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTED---VAGKAYTGR---E 657 Query: 744 KGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALK 803 ++ E+ + R AR P K +V+ + ++ A+TGDG ND PALK Sbjct: 658 FDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFN-----EITAMTGDGVNDAPALK 712 Query: 804 KADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVA 863 KA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+++ ++ NV Sbjct: 713 KAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGE 771 Query: 864 VIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISR 923 V+ F A + L VQ+LWVNL+ D + AL PP ++ + P + LIS Sbjct: 772 VVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISG 831 Query: 924 TMMKNILGHAVY 935 + L VY Sbjct: 832 WLFFRYLAIGVY 843 >gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo sapiens] Length = 1043 Score = 302 bits (773), Expect = 1e-81 Identities = 275/912 (30%), Positives = 415/912 (45%), Gaps = 159/912 (17%) Query: 82 RQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEACGNVS 141 R+ YG N +P ++ K+ +LV E +D+ + IL +AA+VS L+++ EE E Sbjct: 33 RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF----EEGE------ 82 Query: 142 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNG 201 E ++E I+L ++ +V + + + E L+ + K VIR+ Sbjct: 83 -------ETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133 Query: 202 Q--LLQVPVAALVVGDIAQVKYGDLLPADGVLIQ--ANDLKIDESSLTGESDHVRK---- 253 + + ++ +V GDI +V GD +PAD LI+ + L++D+S LTGES V K Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193 Query: 254 -------SADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKG 306 + DK ML SGT++ G AVGV TG+ T LG Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGL-HTELG------------- 233 Query: 307 KQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTK 366 K + Q AV E PL Q KL + Sbjct: 234 ------------KIRSQMAAVEPERTPL--------------------------QRKLDE 255 Query: 367 LAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLV 426 Q+ A +S I V + V+ G +WL V +F I V + V Sbjct: 256 FGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA--------VYYFKIAVALAV 304 Query: 427 VAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVV 486 A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLTTN+M+V Sbjct: 305 AAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC 364 Query: 487 QSYL-----------------GDTHYKEIPAPSALTPKI---LDLLVHAISINSAYTTKI 526 + ++ G T+ E P D LV +I + Sbjct: 365 RMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSA 424 Query: 527 LPPEKEGALPRQVGNKTECALLGFVLDLK---RDFQPVRE--------QIPEDKLYKVYT 575 L + + +VG TE AL V + D Q + + + + K +T Sbjct: 425 LDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFT 484 Query: 576 --FNSVRKSMSTVIRM----PDG-GFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRD 628 F+ RKSMS P G G ++F KGA E ++++C+++ P R+ Sbjct: 485 LEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV-RVGSRTAPLTPTSRE 543 Query: 629 DMVRKIIE-PMACDGLRTICIAYRDFSAGQEP----DWDNENEVVGDLTCIAVVGIEDPV 683 ++ KI + D LR + +A RD +E D + DLT + VG+ DP Sbjct: 544 QILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDPP 603 Query: 684 RPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNE 743 RPEV I +C +AGI V M+TGDN TA AI + GI ED + GK + R E Sbjct: 604 RPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTED---VAGKAYTGR---E 657 Query: 744 KGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALK 803 ++ E+ + R AR P K +V+ + ++ A+TGDG ND PALK Sbjct: 658 FDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFN-----EITAMTGDGVNDAPALK 712 Query: 804 KADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVA 863 KA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+++ ++ NV Sbjct: 713 KAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGE 771 Query: 864 VIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISR 923 V+ F A + L VQ+LWVNL+ D + AL PP ++ + P + LIS Sbjct: 772 VVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISG 831 Query: 924 TMMKNILGHAVY 935 + L VY Sbjct: 832 WLFFRYLAIGVY 843 >gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo sapiens] Length = 1044 Score = 302 bits (773), Expect = 1e-81 Identities = 275/912 (30%), Positives = 415/912 (45%), Gaps = 159/912 (17%) Query: 82 RQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEACGNVS 141 R+ YG N +P ++ K+ +LV E +D+ + IL +AA+VS L+++ EE E Sbjct: 33 RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF----EEGE------ 82 Query: 142 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNG 201 E ++E I+L ++ +V + + + E L+ + K VIR+ Sbjct: 83 -------ETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133 Query: 202 Q--LLQVPVAALVVGDIAQVKYGDLLPADGVLIQ--ANDLKIDESSLTGESDHVRK---- 253 + + ++ +V GDI +V GD +PAD LI+ + L++D+S LTGES V K Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193 Query: 254 -------SADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKG 306 + DK ML SGT++ G AVGV TG+ T LG Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGL-HTELG------------- 233 Query: 307 KQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTK 366 K + Q AV E PL Q KL + Sbjct: 234 ------------KIRSQMAAVEPERTPL--------------------------QRKLDE 255 Query: 367 LAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLV 426 Q+ A +S I V + V+ G +WL V +F I V + V Sbjct: 256 FGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA--------VYYFKIAVALAV 304 Query: 427 VAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVV 486 A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLTTN+M+V Sbjct: 305 AAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC 364 Query: 487 QSYL-----------------GDTHYKEIPAPSALTPKI---LDLLVHAISINSAYTTKI 526 + ++ G T+ E P D LV +I + Sbjct: 365 RMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSA 424 Query: 527 LPPEKEGALPRQVGNKTECALLGFVLDLK---RDFQPVRE--------QIPEDKLYKVYT 575 L + + +VG TE AL V + D Q + + + + K +T Sbjct: 425 LDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFT 484 Query: 576 --FNSVRKSMSTVIRM----PDG-GFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRD 628 F+ RKSMS P G G ++F KGA E ++++C+++ P R+ Sbjct: 485 LEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV-RVGSRTAPLTPTSRE 543 Query: 629 DMVRKIIE-PMACDGLRTICIAYRDFSAGQEP----DWDNENEVVGDLTCIAVVGIEDPV 683 ++ KI + D LR + +A RD +E D + DLT + VG+ DP Sbjct: 544 QILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDPP 603 Query: 684 RPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNE 743 RPEV I +C +AGI V M+TGDN TA AI + GI ED + GK + R E Sbjct: 604 RPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTED---VAGKAYTGR---E 657 Query: 744 KGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALK 803 ++ E+ + R AR P K +V+ + ++ A+TGDG ND PALK Sbjct: 658 FDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFN-----EITAMTGDGVNDAPALK 712 Query: 804 KADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVA 863 KA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+++ ++ NV Sbjct: 713 KAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGE 771 Query: 864 VIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISR 923 V+ F A + L VQ+LWVNL+ D + AL PP ++ + P + LIS Sbjct: 772 VVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISG 831 Query: 924 TMMKNILGHAVY 935 + L VY Sbjct: 832 WLFFRYLAIGVY 843 >gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo sapiens] Length = 1052 Score = 302 bits (773), Expect = 1e-81 Identities = 275/912 (30%), Positives = 415/912 (45%), Gaps = 159/912 (17%) Query: 82 RQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEACGNVS 141 R+ YG N +P ++ K+ +LV E +D+ + IL +AA+VS L+++ EE E Sbjct: 33 RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF----EEGE------ 82 Query: 142 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNG 201 E ++E I+L ++ +V + + + E L+ + K VIR+ Sbjct: 83 -------ETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133 Query: 202 Q--LLQVPVAALVVGDIAQVKYGDLLPADGVLIQ--ANDLKIDESSLTGESDHVRK---- 253 + + ++ +V GDI +V GD +PAD LI+ + L++D+S LTGES V K Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193 Query: 254 -------SADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKG 306 + DK ML SGT++ G AVGV TG+ T LG Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGL-HTELG------------- 233 Query: 307 KQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTK 366 K + Q AV E PL Q KL + Sbjct: 234 ------------KIRSQMAAVEPERTPL--------------------------QRKLDE 255 Query: 367 LAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLV 426 Q+ A +S I V + V+ G +WL V +F I V + V Sbjct: 256 FGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA--------VYYFKIAVALAV 304 Query: 427 VAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVV 486 A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLTTN+M+V Sbjct: 305 AAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC 364 Query: 487 QSYL-----------------GDTHYKEIPAPSALTPKI---LDLLVHAISINSAYTTKI 526 + ++ G T+ E P D LV +I + Sbjct: 365 RMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALCNDSA 424 Query: 527 LPPEKEGALPRQVGNKTECALLGFVLDLK---RDFQPVRE--------QIPEDKLYKVYT 575 L + + +VG TE AL V + D Q + + + + K +T Sbjct: 425 LDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFT 484 Query: 576 --FNSVRKSMSTVIRM----PDG-GFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRD 628 F+ RKSMS P G G ++F KGA E ++++C+++ P R+ Sbjct: 485 LEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV-RVGSRTAPLTPTSRE 543 Query: 629 DMVRKIIE-PMACDGLRTICIAYRDFSAGQEP----DWDNENEVVGDLTCIAVVGIEDPV 683 ++ KI + D LR + +A RD +E D + DLT + VG+ DP Sbjct: 544 QILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDPP 603 Query: 684 RPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNE 743 RPEV I +C +AGI V M+TGDN TA AI + GI ED + GK + R E Sbjct: 604 RPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTED---VAGKAYTGR---E 657 Query: 744 KGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALK 803 ++ E+ + R AR P K +V+ + ++ A+TGDG ND PALK Sbjct: 658 FDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFN-----EITAMTGDGVNDAPALK 712 Query: 804 KADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVA 863 KA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+++ ++ NV Sbjct: 713 KAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGE 771 Query: 864 VIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISR 923 V+ F A + L VQ+LWVNL+ D + AL PP ++ + P + LIS Sbjct: 772 VVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISG 831 Query: 924 TMMKNILGHAVY 935 + L VY Sbjct: 832 WLFFRYLAIGVY 843 >gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sapiens] Length = 939 Score = 300 bits (769), Expect = 4e-81 Identities = 257/929 (27%), Positives = 431/929 (46%), Gaps = 140/929 (15%) Query: 156 EGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGD 215 + +I ++++ VV V ++ EK L + E +R G+L LV GD Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159 Query: 216 IAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMV 275 + GD +PAD L +A DL IDESSLTGE+ K P +G + + Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219 Query: 276 VTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLK 335 T V G++ +G G + Sbjct: 220 GTLVRCGKAKGVV---IGTG---------------------------------------E 237 Query: 336 SAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETF 395 ++E GE+ K A + K+ LQ + L Q+ I II+++ +++ Sbjct: 238 NSEFGEVF----KMMQAEEAPKTPLQKSMDLLGKQLS---FYSFGIIGIIMLVGWLLGKD 290 Query: 396 VVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV 455 ++E F I V++ V A+PEGLP+ VT++LA V +M+K +V Sbjct: 291 ILE------------------MFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIV 332 Query: 456 RHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHA 515 + L ET+G ICSDKTGTLT N MTV + D + E+ + +++V Sbjct: 333 KKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGY--NQFGEVIVDG 390 Query: 516 ISINSAYTTKILPPEKEGALPRQ--------VGNKTECALLGFVLDLKRDFQPVREQIPE 567 ++ Y + + G + +G TE AL+ + + D + + Sbjct: 391 DVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQ 444 Query: 568 DKLYKV-YTFNSVRKSMSTVI---RMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFR 623 D + K Y F+S +K M+ D F KGA E ++K CT S G+ Sbjct: 445 DYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-QSKGQTLTLT 503 Query: 624 PRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPV 683 + RD + ++ M GLR + +A +G E +G LT + +VGI DP Sbjct: 504 QQQRD-VYQQEKARMGSAGLRVLALA-----SGPE---------LGQLTFLGLVGIIDPP 548 Query: 684 RPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNE 743 R V EA+ +G++++M+TGD+ TA AIA++ G+ + G+E + Sbjct: 549 RTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEEIDA----- 601 Query: 744 KGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALK 803 ++ ++L ++ PK+ V R+SP K ++K + + VVA+TGDG ND ALK Sbjct: 602 ---MDVQQLSQIVPKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALK 653 Query: 804 KADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVA 863 AD+G AMG GTDV KEA+D+IL DD+F +I+ A+ G+ +Y++I F++FQL+ ++ A Sbjct: 654 AADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAA 713 Query: 864 VIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISR 923 + + + +PL A+Q+LW+N+IMD + +L EP + ++ + P ++++ Sbjct: 714 LTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTK 773 Query: 924 TMMKNILGHAVYQLAIIFTLLFV--GELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQL 981 ++ IL V + I+ LFV EL ++ + R+ T+ F FV + Sbjct: 774 NLILKIL---VSSIIIVCGTLFVFWRELRDNVITPRDT----------TMTFTCFVFFDM 820 Query: 982 FNEINARKIHGERNVFD-GIFSNPIFCTIVLGTFGIQIVIVQFG--GKPFSCSPLSTEQW 1038 FN +++R ++VF+ G+ SN +FC VLG+ Q++++ F K F LS Sbjct: 821 FNALSSRS--QTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDL 878 Query: 1039 LWCLFVGVGELVWGQVIATIPTSQLKCLK 1067 L+ L + + ++I + S+ K K Sbjct: 879 LFLLGLTSSVCIVAEIIKKVERSREKIQK 907 >gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sapiens] Length = 949 Score = 300 bits (769), Expect = 4e-81 Identities = 257/929 (27%), Positives = 431/929 (46%), Gaps = 140/929 (15%) Query: 156 EGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGD 215 + +I ++++ VV V ++ EK L + E +R G+L LV GD Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159 Query: 216 IAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMV 275 + GD +PAD L +A DL IDESSLTGE+ K P +G + + Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219 Query: 276 VTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLK 335 T V G++ +G G + Sbjct: 220 GTLVRCGKAKGVV---IGTG---------------------------------------E 237 Query: 336 SAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETF 395 ++E GE+ K A + K+ LQ + L Q+ I II+++ +++ Sbjct: 238 NSEFGEVF----KMMQAEEAPKTPLQKSMDLLGKQLS---FYSFGIIGIIMLVGWLLGKD 290 Query: 396 VVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV 455 ++E F I V++ V A+PEGLP+ VT++LA V +M+K +V Sbjct: 291 ILE------------------MFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIV 332 Query: 456 RHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHA 515 + L ET+G ICSDKTGTLT N MTV + D + E+ + +++V Sbjct: 333 KKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGY--NQFGEVIVDG 390 Query: 516 ISINSAYTTKILPPEKEGALPRQ--------VGNKTECALLGFVLDLKRDFQPVREQIPE 567 ++ Y + + G + +G TE AL+ + + D + + Sbjct: 391 DVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQ 444 Query: 568 DKLYKV-YTFNSVRKSMSTVI---RMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFR 623 D + K Y F+S +K M+ D F KGA E ++K CT S G+ Sbjct: 445 DYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-QSKGQTLTLT 503 Query: 624 PRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPV 683 + RD + ++ M GLR + +A +G E +G LT + +VGI DP Sbjct: 504 QQQRD-VYQQEKARMGSAGLRVLALA-----SGPE---------LGQLTFLGLVGIIDPP 548 Query: 684 RPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNE 743 R V EA+ +G++++M+TGD+ TA AIA++ G+ + G+E + Sbjct: 549 RTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEEIDA----- 601 Query: 744 KGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALK 803 ++ ++L ++ PK+ V R+SP K ++K + + VVA+TGDG ND ALK Sbjct: 602 ---MDVQQLSQIVPKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALK 653 Query: 804 KADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVA 863 AD+G AMG GTDV KEA+D+IL DD+F +I+ A+ G+ +Y++I F++FQL+ ++ A Sbjct: 654 AADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAA 713 Query: 864 VIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISR 923 + + + +PL A+Q+LW+N+IMD + +L EP + ++ + P ++++ Sbjct: 714 LTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTK 773 Query: 924 TMMKNILGHAVYQLAIIFTLLFV--GELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQL 981 ++ IL V + I+ LFV EL ++ + R+ T+ F FV + Sbjct: 774 NLILKIL---VSSIIIVCGTLFVFWRELRDNVITPRDT----------TMTFTCFVFFDM 820 Query: 982 FNEINARKIHGERNVFD-GIFSNPIFCTIVLGTFGIQIVIVQFG--GKPFSCSPLSTEQW 1038 FN +++R ++VF+ G+ SN +FC VLG+ Q++++ F K F LS Sbjct: 821 FNALSSRS--QTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDL 878 Query: 1039 LWCLFVGVGELVWGQVIATIPTSQLKCLK 1067 L+ L + + ++I + S+ K K Sbjct: 879 LFLLGLTSSVCIVAEIIKKVERSREKIQK 907 >gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sapiens] Length = 919 Score = 300 bits (769), Expect = 4e-81 Identities = 257/929 (27%), Positives = 431/929 (46%), Gaps = 140/929 (15%) Query: 156 EGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGD 215 + +I ++++ VV V ++ EK L + E +R G+L LV GD Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159 Query: 216 IAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMV 275 + GD +PAD L +A DL IDESSLTGE+ K P +G + + Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219 Query: 276 VTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLK 335 T V G++ +G G + Sbjct: 220 GTLVRCGKAKGVV---IGTG---------------------------------------E 237 Query: 336 SAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETF 395 ++E GE+ K A + K+ LQ + L Q+ I II+++ +++ Sbjct: 238 NSEFGEVF----KMMQAEEAPKTPLQKSMDLLGKQLS---FYSFGIIGIIMLVGWLLGKD 290 Query: 396 VVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV 455 ++E F I V++ V A+PEGLP+ VT++LA V +M+K +V Sbjct: 291 ILE------------------MFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIV 332 Query: 456 RHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHA 515 + L ET+G ICSDKTGTLT N MTV + D + E+ + +++V Sbjct: 333 KKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGY--NQFGEVIVDG 390 Query: 516 ISINSAYTTKILPPEKEGALPRQ--------VGNKTECALLGFVLDLKRDFQPVREQIPE 567 ++ Y + + G + +G TE AL+ + + D + + Sbjct: 391 DVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQ 444 Query: 568 DKLYKV-YTFNSVRKSMSTVI---RMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFR 623 D + K Y F+S +K M+ D F KGA E ++K CT S G+ Sbjct: 445 DYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-QSKGQTLTLT 503 Query: 624 PRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPV 683 + RD + ++ M GLR + +A +G E +G LT + +VGI DP Sbjct: 504 QQQRD-VYQQEKARMGSAGLRVLALA-----SGPE---------LGQLTFLGLVGIIDPP 548 Query: 684 RPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNE 743 R V EA+ +G++++M+TGD+ TA AIA++ G+ + G+E + Sbjct: 549 RTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEEIDA----- 601 Query: 744 KGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALK 803 ++ ++L ++ PK+ V R+SP K ++K + + VVA+TGDG ND ALK Sbjct: 602 ---MDVQQLSQIVPKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALK 653 Query: 804 KADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVA 863 AD+G AMG GTDV KEA+D+IL DD+F +I+ A+ G+ +Y++I F++FQL+ ++ A Sbjct: 654 AADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAA 713 Query: 864 VIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISR 923 + + + +PL A+Q+LW+N+IMD + +L EP + ++ + P ++++ Sbjct: 714 LTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTK 773 Query: 924 TMMKNILGHAVYQLAIIFTLLFV--GELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQL 981 ++ IL V + I+ LFV EL ++ + R+ T+ F FV + Sbjct: 774 NLILKIL---VSSIIIVCGTLFVFWRELRDNVITPRDT----------TMTFTCFVFFDM 820 Query: 982 FNEINARKIHGERNVFD-GIFSNPIFCTIVLGTFGIQIVIVQFG--GKPFSCSPLSTEQW 1038 FN +++R ++VF+ G+ SN +FC VLG+ Q++++ F K F LS Sbjct: 821 FNALSSRS--QTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDL 878 Query: 1039 LWCLFVGVGELVWGQVIATIPTSQLKCLK 1067 L+ L + + ++I + S+ K K Sbjct: 879 LFLLGLTSSVCIVAEIIKKVERSREKIQK 907 >gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sapiens] Length = 888 Score = 297 bits (761), Expect = 4e-80 Identities = 247/883 (27%), Positives = 414/883 (46%), Gaps = 138/883 (15%) Query: 156 EGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGD 215 + +I ++++ VV V ++ EK L + E +R G+L LV GD Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159 Query: 216 IAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMV 275 + GD +PAD L +A DL IDESSLTGE+ K P +G + + Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219 Query: 276 VTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLK 335 T V G++ +G G + Sbjct: 220 GTLVRCGKAKGVV---IGTG---------------------------------------E 237 Query: 336 SAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETF 395 ++E GE+ K A + K+ LQ + L Q+ I II+++ +++ Sbjct: 238 NSEFGEVF----KMMQAEEAPKTPLQKSMDLLGKQLS---FYSFGIIGIIMLVGWLLGKD 290 Query: 396 VVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV 455 ++E F I V++ V A+PEGLP+ VT++LA V +M+K +V Sbjct: 291 ILE------------------MFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIV 332 Query: 456 RHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHA 515 + L ET+G ICSDKTGTLT N MTV + D + E+ + +++V Sbjct: 333 KKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGY--NQFGEVIVDG 390 Query: 516 ISINSAYTTKILPPEKEGALPRQ--------VGNKTECALLGFVLDLKRDFQPVREQIPE 567 ++ Y + + G + +G TE AL+ + + D + + Sbjct: 391 DVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQ 444 Query: 568 DKLYKV-YTFNSVRKSMSTVI---RMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFR 623 D + K Y F+S +K M+ D F KGA E ++K CT S G+ Sbjct: 445 DYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-QSKGQTLTLT 503 Query: 624 PRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPV 683 + RD + ++ M GLR + +A +G E +G LT + +VGI DP Sbjct: 504 QQQRD-VYQQEKARMGSAGLRVLALA-----SGPE---------LGQLTFLGLVGIIDPP 548 Query: 684 RPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNE 743 R V EA+ +G++++M+TGD+ TA AIA++ G+ + G+E + Sbjct: 549 RTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEEIDA----- 601 Query: 744 KGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALK 803 ++ ++L ++ PK+ V R+SP K ++K + + VVA+TGDG ND ALK Sbjct: 602 ---MDVQQLSQIVPKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALK 653 Query: 804 KADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVA 863 AD+G AMG GTDV KEA+D+IL DD+F +I+ A+ G+ +Y++I F++FQL+ ++ A Sbjct: 654 AADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAA 713 Query: 864 VIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISR 923 + + + +PL A+Q+LW+N+IMD + +L EP + ++ + P ++++ Sbjct: 714 LTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTK 773 Query: 924 TMMKNILGHAVYQLAIIFTLLFV--GELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQL 981 ++ IL V + I+ LFV EL ++ + R+ T+ F FV + Sbjct: 774 NLILKIL---VSSIIIVCGTLFVFWRELRDNVITPRDT----------TMTFTCFVFFDM 820 Query: 982 FNEINARKIHGERNVFD-GIFSNPIFCTIVLGTFGIQIVIVQF 1023 FN +++R ++VF+ G+ SN +FC VLG+ Q++++ F Sbjct: 821 FNALSSRS--QTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYF 861 >gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [Homo sapiens] Length = 994 Score = 285 bits (730), Expect = 1e-76 Identities = 270/916 (29%), Positives = 412/916 (44%), Gaps = 163/916 (17%) Query: 66 SPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLS 125 S T GL + +++ + YG N +P ++ KT +LV E +D+ + IL +AA +S L+ Sbjct: 19 SETTGLTPD--QVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLA 76 Query: 126 FYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGL 185 ++ EE E E ++E ILL +I +V + + + E L Sbjct: 77 WF----EEGE-------------ETITAFVEPFVILLILIANAIVGVWQERNAENAIEAL 119 Query: 186 QSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADG--VLIQANDLKIDESS 243 + + K + ++ +V GDI +V GD +PAD + I++ L++D+S Sbjct: 120 KEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSI 179 Query: 244 LTGESDHVRK-----------SADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLL 292 LTGES V K + DK ML SGT++ G A+G+ + TG+ Sbjct: 180 LTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGK------ALGIVATTGV----- 228 Query: 293 GAGGEEEEKKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANA 352 G E GK +D Q A +QD Sbjct: 229 ---GTEI------GKIRD------QMAATEQD---------------------------- 245 Query: 353 PKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQ 412 K+ LQ KL + Q+ K V+S I V + ++ V G +W Sbjct: 246 ----KTPLQQKLDEFGEQLSK---VISLICVAVWLINIGHFNDPVHGGSWFRGA------ 292 Query: 413 YFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICS 472 + +F I V + V A+PEGLP +T LA ++M K N +VR L + ET+G + ICS Sbjct: 293 --IYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICS 350 Query: 473 DKTGTLTTNRMTVVQSYL-----------------GDTHYKE---IPAPSALTPKILDLL 512 DKTGTLTTN+M+V + ++ G T+ E + + P D L Sbjct: 351 DKTGTLTTNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGL 410 Query: 513 VHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFVLDLKRDFQPVRE--------- 563 V +I + L + + +VG TE AL V + VR Sbjct: 411 VELATICALCNDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANA 470 Query: 564 --QIPEDKLYKVYT--FNSVRKSMSTVIRMPDG-----GFRLFSKGASEILLKKCTNILN 614 + + K +T F+ RKSMS G ++F KGA E ++ +C + Sbjct: 471 CNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYV-- 528 Query: 615 SNGELRGFRPRDRDDMVRKIIEPMAC--DGLRTICIAYRDFSAGQEP----DWDNENEVV 668 G R + + +I+ D LR + +A RD +E D E Sbjct: 529 RVGTTRVPLTGPVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYE 588 Query: 669 GDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDF 728 DLT + VVG+ DP R EV +I+ C+ AGI V M+TGDN TA AI + GI E+ Sbjct: 589 TDLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEV 648 Query: 729 L--CLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQR 786 G+EF+ E+ E + AR P+ K +V+ + Sbjct: 649 ADRAYTGREFDDLPLAEQREACRRAC--------CFARVEPSHKSKIVEYL-----QSYD 695 Query: 787 QVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVY 846 ++ A+TGDG ND PALKKA++G AMG +GT VAK AS+++L DDNF++IV AV GR +Y Sbjct: 696 EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIY 754 Query: 847 DSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTE 906 +++ +F+++ ++ NV V+ F A + L VQ+LWVNL+ D + AL PP Sbjct: 755 NNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDL 814 Query: 907 SLLLRKPYGRDKPLIS 922 ++ R P +PLIS Sbjct: 815 DIMDRPPRSPKEPLIS 830 >gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [Homo sapiens] Length = 1001 Score = 285 bits (730), Expect = 1e-76 Identities = 270/916 (29%), Positives = 412/916 (44%), Gaps = 163/916 (17%) Query: 66 SPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLS 125 S T GL + +++ + YG N +P ++ KT +LV E +D+ + IL +AA +S L+ Sbjct: 19 SETTGLTPD--QVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLA 76 Query: 126 FYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGL 185 ++ EE E E ++E ILL +I +V + + + E L Sbjct: 77 WF----EEGE-------------ETITAFVEPFVILLILIANAIVGVWQERNAENAIEAL 119 Query: 186 QSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADG--VLIQANDLKIDESS 243 + + K + ++ +V GDI +V GD +PAD + I++ L++D+S Sbjct: 120 KEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSI 179 Query: 244 LTGESDHVRK-----------SADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLL 292 LTGES V K + DK ML SGT++ G A+G+ + TG+ Sbjct: 180 LTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGK------ALGIVATTGV----- 228 Query: 293 GAGGEEEEKKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANA 352 G E GK +D Q A +QD Sbjct: 229 ---GTEI------GKIRD------QMAATEQD---------------------------- 245 Query: 353 PKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQ 412 K+ LQ KL + Q+ K V+S I V + ++ V G +W Sbjct: 246 ----KTPLQQKLDEFGEQLSK---VISLICVAVWLINIGHFNDPVHGGSWFRGA------ 292 Query: 413 YFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICS 472 + +F I V + V A+PEGLP +T LA ++M K N +VR L + ET+G + ICS Sbjct: 293 --IYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICS 350 Query: 473 DKTGTLTTNRMTVVQSYL-----------------GDTHYKE---IPAPSALTPKILDLL 512 DKTGTLTTN+M+V + ++ G T+ E + + P D L Sbjct: 351 DKTGTLTTNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGL 410 Query: 513 VHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFVLDLKRDFQPVRE--------- 563 V +I + L + + +VG TE AL V + VR Sbjct: 411 VELATICALCNDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANA 470 Query: 564 --QIPEDKLYKVYT--FNSVRKSMSTVIRMPDG-----GFRLFSKGASEILLKKCTNILN 614 + + K +T F+ RKSMS G ++F KGA E ++ +C + Sbjct: 471 CNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYV-- 528 Query: 615 SNGELRGFRPRDRDDMVRKIIEPMAC--DGLRTICIAYRDFSAGQEP----DWDNENEVV 668 G R + + +I+ D LR + +A RD +E D E Sbjct: 529 RVGTTRVPLTGPVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYE 588 Query: 669 GDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDF 728 DLT + VVG+ DP R EV +I+ C+ AGI V M+TGDN TA AI + GI E+ Sbjct: 589 TDLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEV 648 Query: 729 L--CLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQR 786 G+EF+ E+ E + AR P+ K +V+ + Sbjct: 649 ADRAYTGREFDDLPLAEQREACRRAC--------CFARVEPSHKSKIVEYL-----QSYD 695 Query: 787 QVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVY 846 ++ A+TGDG ND PALKKA++G AMG +GT VAK AS+++L DDNF++IV AV GR +Y Sbjct: 696 EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIY 754 Query: 847 DSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTE 906 +++ +F+++ ++ NV V+ F A + L VQ+LWVNL+ D + AL PP Sbjct: 755 NNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDL 814 Query: 907 SLLLRKPYGRDKPLIS 922 ++ R P +PLIS Sbjct: 815 DIMDRPPRSPKEPLIS 830 >gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo sapiens] Length = 997 Score = 283 bits (723), Expect = 9e-76 Identities = 264/915 (28%), Positives = 410/915 (44%), Gaps = 158/915 (17%) Query: 78 LEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEAC 137 ++K ++ +G N +P ++ KT L+LV E +D+ + IL +AA +S L+++ EE E Sbjct: 29 VKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWF----EEGE-- 82 Query: 138 GNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTV 197 E ++E ILL ++ +V + + + E L+ + K Sbjct: 83 -----------ETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYR 131 Query: 198 IRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVL--IQANDLKIDESSLTGESDHVRKSA 255 + ++ +V GDI ++ GD +PAD L I++ L++D+S LTGES V K Sbjct: 132 QDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHT 191 Query: 256 DKDP-----------MLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDK 304 D P ML SGT++ G A+GV TG+ + Sbjct: 192 DPVPDPRAVNQDKKNMLFSGTNIAAGK------AMGVVVATGVNTEI------------- 232 Query: 305 KGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKL 364 K +D VA E +E++ LQ KL Sbjct: 233 ---------------GKIRDEMVATE------------------------QERTPLQQKL 253 Query: 365 TKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTV 424 + Q+ K V+S I + + ++ V G +W+ + +F I V + Sbjct: 254 DEFGEQLSK---VISLICIAVWIINIGHFNDPVHGGSWIRGA--------IYYFKIAVAL 302 Query: 425 LVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMT 484 V A+PEGLP +T LA ++M K N +VR L + ET+G + ICSDKTGTLTTN+M+ Sbjct: 303 AVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMS 362 Query: 485 VVQSYL-----GDT-HYKEIPAPSALTPKI--------------LDLLVHAISINSAYTT 524 V + ++ GDT E + I D LV +I + Sbjct: 363 VCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCND 422 Query: 525 KILPPEKEGALPRQVGNKTECALLGFVLDL-----------KRDFQPVREQIPEDKLYKV 573 L + + +VG TE AL V + K + + + + K Sbjct: 423 SALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKE 482 Query: 574 YT--FNSVRKSMSTVIRMPDGGFR-----LFSKGASEILLKKCTNILNSNGELRGFRPRD 626 +T F+ RKSMS V P+ R +F KGA E ++ +CT+I G + Sbjct: 483 FTLEFSRDRKSMS-VYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHI--RVGSTKVPMTSG 539 Query: 627 RDDMVRKIIEPMAC--DGLRTICIAYRDFSAGQEP----DWDNENEVVGDLTCIAVVGIE 680 + +I D LR + +A D +E D N + +LT + VG+ Sbjct: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 599 Query: 681 DPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRI 740 DP R EV +++ C++AGI V M+TGDN TA AI + GI ED + K F R Sbjct: 600 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDED---VTSKAFTGR- 655 Query: 741 RNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGP 800 E E+ R AR P+ K +V+ + ++ A+TGDG ND P Sbjct: 656 --EFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFD-----EITAMTGDGVNDAP 708 Query: 801 ALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVN 860 ALKKA++G AMG +GT VAK AS+++L DDNF++IV AV GR +Y+++ +F+++ ++ N Sbjct: 709 ALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSN 767 Query: 861 VVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPL 920 V V+ F A + L VQ+LWVNL+ D + AL PP ++ + P +PL Sbjct: 768 VGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPL 827 Query: 921 ISRTMMKNILGHAVY 935 IS + L Y Sbjct: 828 ISGWLFFRYLAIGCY 842 >gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [Homo sapiens] Length = 1042 Score = 283 bits (723), Expect = 9e-76 Identities = 264/915 (28%), Positives = 410/915 (44%), Gaps = 158/915 (17%) Query: 78 LEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEAC 137 ++K ++ +G N +P ++ KT L+LV E +D+ + IL +AA +S L+++ EE E Sbjct: 29 VKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWF----EEGE-- 82 Query: 138 GNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTV 197 E ++E ILL ++ +V + + + E L+ + K Sbjct: 83 -----------ETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYR 131 Query: 198 IRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVL--IQANDLKIDESSLTGESDHVRKSA 255 + ++ +V GDI ++ GD +PAD L I++ L++D+S LTGES V K Sbjct: 132 QDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHT 191 Query: 256 DKDP-----------MLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDK 304 D P ML SGT++ G A+GV TG+ + Sbjct: 192 DPVPDPRAVNQDKKNMLFSGTNIAAGK------AMGVVVATGVNTEI------------- 232 Query: 305 KGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKL 364 K +D VA E +E++ LQ KL Sbjct: 233 ---------------GKIRDEMVATE------------------------QERTPLQQKL 253 Query: 365 TKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTV 424 + Q+ K V+S I + + ++ V G +W+ + +F I V + Sbjct: 254 DEFGEQLSK---VISLICIAVWIINIGHFNDPVHGGSWIRGA--------IYYFKIAVAL 302 Query: 425 LVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMT 484 V A+PEGLP +T LA ++M K N +VR L + ET+G + ICSDKTGTLTTN+M+ Sbjct: 303 AVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMS 362 Query: 485 VVQSYL-----GDT-HYKEIPAPSALTPKI--------------LDLLVHAISINSAYTT 524 V + ++ GDT E + I D LV +I + Sbjct: 363 VCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCND 422 Query: 525 KILPPEKEGALPRQVGNKTECALLGFVLDL-----------KRDFQPVREQIPEDKLYKV 573 L + + +VG TE AL V + K + + + + K Sbjct: 423 SALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKE 482 Query: 574 YT--FNSVRKSMSTVIRMPDGGFR-----LFSKGASEILLKKCTNILNSNGELRGFRPRD 626 +T F+ RKSMS V P+ R +F KGA E ++ +CT+I G + Sbjct: 483 FTLEFSRDRKSMS-VYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHI--RVGSTKVPMTSG 539 Query: 627 RDDMVRKIIEPMAC--DGLRTICIAYRDFSAGQEP----DWDNENEVVGDLTCIAVVGIE 680 + +I D LR + +A D +E D N + +LT + VG+ Sbjct: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 599 Query: 681 DPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRI 740 DP R EV +++ C++AGI V M+TGDN TA AI + GI ED + K F R Sbjct: 600 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDED---VTSKAFTGR- 655 Query: 741 RNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGP 800 E E+ R AR P+ K +V+ + ++ A+TGDG ND P Sbjct: 656 --EFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFD-----EITAMTGDGVNDAP 708 Query: 801 ALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVN 860 ALKKA++G AMG +GT VAK AS+++L DDNF++IV AV GR +Y+++ +F+++ ++ N Sbjct: 709 ALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSN 767 Query: 861 VVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPL 920 V V+ F A + L VQ+LWVNL+ D + AL PP ++ + P +PL Sbjct: 768 VGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPL 827 Query: 921 ISRTMMKNILGHAVY 935 IS + L Y Sbjct: 828 ISGWLFFRYLAIGCY 842 >gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] Length = 1013 Score = 267 bits (682), Expect = 5e-71 Identities = 249/846 (29%), Positives = 390/846 (46%), Gaps = 141/846 (16%) Query: 140 VSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVI 198 + G ED+ + ++ I+L+ + V++ F+ + + K + ++S + Q+ VI Sbjct: 107 IQAGTEDDPSGDNLYL---GIVLAAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVI 162 Query: 199 RNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSAD-- 256 R G+ +QV +VVGD+ ++K GD +PAD +I A+ K+D SSLTGES+ +S D Sbjct: 163 REGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCT 222 Query: 257 -KDPM-----LLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQD 310 +P+ T+ +EG+ R VV A G + G I TL A G E K Sbjct: 223 HDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATL--ASGLEVGKT-------- 272 Query: 311 GAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQ 370 +A+E++ +T +AV Sbjct: 273 ---------------PIAIEIEHFIQL--------------------------ITGVAVF 291 Query: 371 IGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVP 430 +G + ++S I G TWL F+IG ++V VP Sbjct: 292 LGVSFFILSLIL----------------GYTWLE----------AVIFLIG--IIVANVP 323 Query: 431 EGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYL 490 EGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMTV + Sbjct: 324 EGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWF 383 Query: 491 GDTHYKEIPAPSALTPKILDLLVH---AISINSAYTTKILPPEKEGALP---RQV-GNKT 543 D E + D H A+S + + + + +P R V G+ + Sbjct: 384 -DNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDAS 442 Query: 544 ECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMP---DGGFRLFSKG 600 E ALL + + +RE+ +K FNS K ++ D + L KG Sbjct: 443 ESALLKCIELSSGSVKLMRER---NKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKG 499 Query: 601 ASEILLKKCTNILNSNGELRGFRPRDRD--DMVRKIIEPMACDGLRTI--CIAY---RDF 653 A E +L +C+ IL E +P D + + + + G R + C Y F Sbjct: 500 APERILDRCSTILLQGKE----QPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQF 555 Query: 654 SAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTAR 713 G D D+ N +L + ++ + DP R VP+A+ KC+ AGI V MVTGD+ TA+ Sbjct: 556 PKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAK 615 Query: 714 AIAAKCGIIQPGEDF-------LCLEGKEFNRRIR-------NEKGEIEQERLDKVWPKL 759 AIA GII G + L + + N R + + E++D++ Sbjct: 616 AIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNH 675 Query: 760 R--VLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTD 817 V AR+SP K +V+G Q +VAVTGDG ND PALKKAD+G AMGIAG+D Sbjct: 676 TEIVFARTSPQQKLIIVEG-----CQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSD 730 Query: 818 VAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDS 877 V+K+A+D+IL DDNF SIV V GR ++D++ K + + LT N+ + Sbjct: 731 VSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPL 790 Query: 878 PLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQL 937 PL + +L ++L D +++LA E ++ R+P P + + + ++ A Q+ Sbjct: 791 PLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQP---RNPRTDKLVNERLISMAYGQI 847 Query: 938 AIIFTL 943 +I L Sbjct: 848 GMIQAL 853 >gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 [Homo sapiens] Length = 1015 Score = 257 bits (656), Expect = 5e-68 Identities = 252/902 (27%), Positives = 397/902 (44%), Gaps = 159/902 (17%) Query: 78 LEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEAC 137 ++K ++ +G N +P ++ KT L+LV E +D+ + IL +AA +S L+++ EE E Sbjct: 29 VKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWF----EEGE-- 82 Query: 138 GNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTV 197 E ++E ILL ++ +V + + + E L+ + K V Sbjct: 83 -----------ETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGK--V 129 Query: 198 IRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSADK 257 R + + ++K D++P D V I + + + + D + DK Sbjct: 130 YRQDRK-----------SVQRIKAKDIVPGDIVEIAGESVSVIKHT-DPVPDPRAVNQDK 177 Query: 258 DPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQ 317 ML SGT++ G A+GV TG+ + Sbjct: 178 KNMLFSGTNIAAGK------AMGVVVATGVNTEI-------------------------- 205 Query: 318 TKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLV 377 K +D VA E +E++ LQ KL + Q+ K V Sbjct: 206 --GKIRDEMVATE------------------------QERTPLQQKLDEFGEQLSK---V 236 Query: 378 MSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAV 437 +S I + + ++ V G +W+ + +F I V + V A+PEGLP + Sbjct: 237 ISLICIAVWIINIGHFNDPVHGGSWIRGA--------IYYFKIAVALAVAAIPEGLPAVI 288 Query: 438 TISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYL-----GD 492 T LA ++M K N +VR L + ET+G + ICSDKTGTLTTN+M+V + ++ GD Sbjct: 289 TTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGD 348 Query: 493 T-HYKEIPAPSALTPKI--------------LDLLVHAISINSAYTTKILPPEKEGALPR 537 T E + I D LV +I + L + + Sbjct: 349 TCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSALDYNEAKGVYE 408 Query: 538 QVGNKTECALLGFVLDL-----------KRDFQPVREQIPEDKLYKVYT--FNSVRKSMS 584 +VG TE AL V + K + + + + K +T F+ RKSMS Sbjct: 409 KVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMS 468 Query: 585 TVIRMPDGGFR-----LFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMA 639 V P+ R +F KGA E ++ +CT+I G + + +I Sbjct: 469 -VYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHI--RVGSTKVPMTSGVKQKIMSVIREWG 525 Query: 640 C--DGLRTICIAYRDFSAGQEP----DWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRK 693 D LR + +A D +E D N + +LT + VG+ DP R EV +++ Sbjct: 526 SGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKL 585 Query: 694 CQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLD 753 C++AGI V M+TGDN TA AI + GI ED + K F R E E+ Sbjct: 586 CRQAGIRVIMITGDNKGTAVAICRRIGIFGQDED---VTSKAFTGR---EFDELNPSAQR 639 Query: 754 KVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGI 813 R AR P+ K +V+ + ++ A+TGDG ND PALKKA++G AMG Sbjct: 640 DACLNARCFARVEPSHKSKIVEFLQSFD-----EITAMTGDGVNDAPALKKAEIGIAMG- 693 Query: 814 AGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACI 873 +GT VAK AS+++L DDNF++IV AV GR +Y+++ +F+++ ++ NV V+ F A + Sbjct: 694 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL 753 Query: 874 TQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRTMMKNILGHA 933 L VQ+LWVNL+ D + AL PP ++ + P +PLIS + L Sbjct: 754 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG 813 Query: 934 VY 935 Y Sbjct: 814 CY 815 >gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] Length = 1039 Score = 247 bits (631), Expect = 4e-65 Identities = 194/594 (32%), Positives = 304/594 (51%), Gaps = 74/594 (12%) Query: 365 TKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTV 424 T +A++I +++ + V I +L+F+I V ++Y V II + Sbjct: 297 TPIAIEIEHFVHIVAGVAVSIGILFFIIA---------------VSLKYQVLDSIIFLIG 341 Query: 425 LVVA-VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRM 483 ++VA VPEGL VT++L+ + K+M K N LV++L+A ET+G+ + ICSDKTGTLT NRM Sbjct: 342 IIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRM 401 Query: 484 TVV------QSYLGDT---HYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGA 534 TV Q ++ DT H ++ S+ T L ++ + + P ++ Sbjct: 402 TVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIITLCN-----RAEFKPGQENVP 456 Query: 535 LPRQ--VGNKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDG 592 + ++ +G+ +E ALL F + D +R++ ++ FNS K ++ M D Sbjct: 457 IMKKAVIGDASETALLKFSEVILGDVMEIRKR---NRKVAEIPFNSTNKFQLSIHEMDDP 513 Query: 593 G---FRLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGL--RTIC 647 F + KGA E +L+KC+ I+ + E P D+ M GL R + Sbjct: 514 HGKRFLMVMKGAPERILEKCSTIMINGEE----HPLDKSTAKTFHTAYMELGGLGERVLG 569 Query: 648 IAYRDFSAGQEP-----DWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVR 702 + A + P D D N +L + ++ + DP R VP+A+ KC+ AGI V Sbjct: 570 FCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVI 629 Query: 703 MVTGDNINTARAIAAKCGIIQPGEDF-------LCLEGKEFNRRIRN-------EKGEIE 748 MVTGD+ TA+AIA GII + L + ++ N+R E ++ Sbjct: 630 MVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMS 689 Query: 749 QERLDKVWPKLR--VLARSSPTDKHTLVKGIIDSTTGEQRQ--VVAVTGDGTNDGPALKK 804 E+LD++ + V AR+SP K +V+G QRQ VVAVTGDG ND PALKK Sbjct: 690 SEQLDEILANYQEIVFARTSPQQKLIIVEGC-------QRQDAVVAVTGDGVNDSPALKK 742 Query: 805 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 864 AD+G AMGIAG+D AK A+D++L DDNF SIV V GR ++D++ K + + LT N+ + Sbjct: 743 ADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAEL 802 Query: 865 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDK 918 + P+ + +L+++L D S+ALA E ++ RKP ++K Sbjct: 803 CPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNK 856 Score = 58.9 bits (141), Expect = 3e-08 Identities = 43/143 (30%), Positives = 74/143 (51%), Gaps = 10/143 (6%) Query: 167 VVLVTAFNDWSKEKQFRGLQSRIEQ--EQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDL 224 VV++T + +E + + S + Q+ VIR+ + +P LVVGDI +VK GD Sbjct: 154 VVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQ 213 Query: 225 LPADGVLIQANDLKIDESSLTGESDHVRKSAD---KDPM-----LLSGTHVMEGSGRMVV 276 +PAD ++ + ++D SSLTGES+ +S++ ++P+ T +EG+ +V Sbjct: 214 IPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMV 273 Query: 277 TAVGVNSQTGIIFTLLGAGGEEE 299 G + G I +L G E+ Sbjct: 274 INTGDRTIIGHIASLASGVGNEK 296 >gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo sapiens] Length = 946 Score = 241 bits (615), Expect = 3e-63 Identities = 191/618 (30%), Positives = 303/618 (49%), Gaps = 59/618 (9%) Query: 415 VKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDK 474 + F IGV++ V A+PEGLP+ V ++L V +M K +V+ L ET+G + +CSDK Sbjct: 321 LSMFTIGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCSVLCSDK 380 Query: 475 TGTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGA 534 TGTLT N MTV Q D E+ + LL I + + G Sbjct: 381 TGTLTANEMTVTQLVTSDGLRAEVSGVGYDGQGTVCLLPSKEVIKEFSNVSVGKLVEAGC 440 Query: 535 LPRQ--------VGNKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTV 586 + +G TE AL+ L +K D ++ K F+S +K M+ Sbjct: 441 VANNAVIRKNAVMGQPTEGALMA--LAMKMDLSDIKNSYIRKK---EIPFSSEQKWMAVK 495 Query: 587 --IRMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLR 644 ++ D F KGA E +++ CT + N+ G P+ R +++ + M GLR Sbjct: 496 CSLKTEDQEDIYFMKGALEEVIRYCT-MYNNGGIPLPLTPQQRSFCLQEE-KRMGSLGLR 553 Query: 645 TICIAYRDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMV 704 + +A +G E +G LT + +VGI DP R V EA++ +G++V+M+ Sbjct: 554 VLALA-----SGPE---------LGRLTFLGLVGIIDPPRVGVKEAVQVLSESGVSVKMI 599 Query: 705 TGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLAR 764 TGD + TA AI G+ + G+E + EKGE+ D+V K+ V R Sbjct: 600 TGDALETALAIGRNIGLCNG--KLQAMSGEEVDSV---EKGELA----DRVG-KVSVFFR 649 Query: 765 SSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASD 824 +SP K ++K + +S +VA+TGDG ND ALK AD+G AMG GTDV+KEA++ Sbjct: 650 TSPKHKLKIIKALQESGA-----IVAMTGDGVNDAVALKSADIGIAMGQTGTDVSKEAAN 704 Query: 825 IILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQM 884 +IL DD+F++I+ AV G+ ++ +I F++FQL+ ++ A+ + SPL A+Q+ Sbjct: 705 MILVDDDFSAIMNAVEEGKGIFYNIKNFVRFQLSTSISALSLITLSTVFNLPSPLNAMQI 764 Query: 885 LWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLAIIFTLL 944 LW+N+IMD + +L EP + + P ++SR ++ IL A ++ Sbjct: 765 LWINIIMDGPPAQSLGVEPVDKDAFRQPPRSVRDTILSRALILKILMSA--------AII 816 Query: 945 FVGELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFD-GIFSN 1003 G LF +P + T+ F FV LFN + R + +F+ G N Sbjct: 817 ISGTLFIFWKEMPEDRASTPRTT--TMTFTCFVFFDLFNALTCRS--QTKLIFEIGFLRN 872 Query: 1004 PIFCTIVLGTFGIQIVIV 1021 +F VLG+ Q+ ++ Sbjct: 873 HMFLYSVLGSILGQLAVI 890 Score = 69.3 bits (168), Expect = 2e-11 Identities = 51/169 (30%), Positives = 79/169 (46%), Gaps = 20/169 (11%) Query: 156 EGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGD 215 + +I +V+ VV V ++ EK L + E +R G+L + LV GD Sbjct: 133 DAVSIATAVLVVVTVAFIQEYRSEKSLEELTKMVPPE--CNCLREGKLQHLLARELVPGD 190 Query: 216 IAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKS----------ADKDPMLLSGT 265 + + GD +PAD L + DL +DESS TGE++ K+ ++ GT Sbjct: 191 VVSLSIGDRIPADIRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGGDLTTLSNIVFMGT 250 Query: 266 HVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEE------EEKKDKKGKQ 308 V G G+ VV G +SQ G +F ++ A EE ++ D+ GKQ Sbjct: 251 LVQYGRGQGVVIGTGESSQFGEVFKMMQA--EETPKTPLQKSMDRLGKQ 297 >gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapiens] Length = 1023 Score = 232 bits (591), Expect = 2e-60 Identities = 194/621 (31%), Positives = 307/621 (49%), Gaps = 67/621 (10%) Query: 358 SVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKF 417 S L+G T +A +I +++ + V + V +F++ ++ TWL Sbjct: 275 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILS--LILEYTWLEAV----------I 322 Query: 418 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 477 F+IG+ +V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGT Sbjct: 323 FLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 380 Query: 478 LTTNRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVH---AISINSAYTTKILPPEKEGA 534 LT NRMTV + D E + D A+S + + + + Sbjct: 381 LTQNRMTVAHMWF-DNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQEN 439 Query: 535 LP----RQVGNKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMP 590 LP G+ +E ALL + + +RE+ K+ ++ FNS K ++ + P Sbjct: 440 LPILKRAVAGDASESALLKCIELCCGSVKEMRERYA--KIVEI-PFNSTNKYQLSIHKNP 496 Query: 591 DGG---FRLFSKGASEILLKKCTNILNSNGELRGFRPRDRD--DMVRKIIEPMACDGLRT 645 + L KGA E +L +C++IL E +P D + D + + G R Sbjct: 497 NTSEPQHLLVMKGAPERILDRCSSILLHGKE----QPLDEELKDAFQNAYLELGGLGERV 552 Query: 646 ICIAY-----RDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGIT 700 + + F G + D D+ N + +L + ++ + DP R VP+A+ KC+ AGI Sbjct: 553 LGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIK 612 Query: 701 VRMVTGDNINTARAIAAKCGIIQPGEDF-------LCLEGKEFNRRIR-------NEKGE 746 V MVTGD+ TA+AIA GII G + L + + N R ++ + Sbjct: 613 VIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKD 672 Query: 747 IEQERLDKV--WPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQ--VVAVTGDGTNDGPAL 802 + E+LD + + V AR+SP K +V+G QRQ +VAVTGDG ND PAL Sbjct: 673 MTSEQLDDILKYHTEIVFARTSPQQKLIIVEGC-------QRQGAIVAVTGDGVNDSPAL 725 Query: 803 KKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVV 862 KKAD+G AMGIAG+DV+K+A+D+IL DDNF SIV V GR ++D++ K + + LT N+ Sbjct: 726 KKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIP 785 Query: 863 AVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLIS 922 + PL V +L ++L D +++LA E ++ R+P P Sbjct: 786 EITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQP---RNPKTD 842 Query: 923 RTMMKNILGHAVYQLAIIFTL 943 + + + ++ A Q+ +I L Sbjct: 843 KLVNERLISMAYGQIGMIQAL 863 Score = 72.0 bits (175), Expect = 3e-12 Identities = 48/141 (34%), Positives = 80/141 (56%), Gaps = 10/141 (7%) Query: 160 ILLSVICVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVIRNGQLLQVPVAALVVGDIAQ 218 ++LS + V++ F+ + + K + ++S + Q+ VIRNG+ + + +VVGD+ + Sbjct: 134 VVLSAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVE 192 Query: 219 VKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSAD---KDPM-----LLSGTHVMEG 270 VK GD +PAD +I AN K+D SSLTGES+ +S D ++P+ T+ +EG Sbjct: 193 VKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEG 252 Query: 271 SGRMVVTAVGVNSQTGIIFTL 291 + R +V G + G I TL Sbjct: 253 TARGIVVYTGDRTVMGRIATL 273 >gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] Length = 1020 Score = 232 bits (591), Expect = 2e-60 Identities = 230/802 (28%), Positives = 359/802 (44%), Gaps = 160/802 (19%) Query: 167 VVLVTAFNDWSKEKQFRGLQSRIEQ--EQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDL 224 VV+VT + +E + + + Q+ VIR G+ +Q+ +VVGD+ +VK GD Sbjct: 137 VVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDR 196 Query: 225 LPADGVLIQANDLKIDESSLTGESDHVRKSAD---KDPM-----LLSGTHVMEGSGRMVV 276 +PAD +I ++ K+D SSLTGES+ +S + ++P+ T+ +EG+ R +V Sbjct: 197 VPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIV 256 Query: 277 TAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKS 336 A G + G I TL +E +T +AME++ Sbjct: 257 IATGDRTVMGRIATLA------------------SGLEVGRT-------PIAMEIEHFIQ 291 Query: 337 AEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFV 396 +T +AV +G + V+S I Sbjct: 292 L--------------------------ITGVAVFLGVSFFVLSLIL-------------- 311 Query: 397 VEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVR 456 G +WL V + + + V ++A + + +T++ +K NL Sbjct: 312 --GYSWLEA-----VIFLIGIIVANVPEGLLAT---VTVCLTLTAKRMARKNCLVKNL-- 359 Query: 457 HLDACETMGNATAICSDKTGTLTTNRMTVVQSYL--------------GDTHYKEIPAPS 502 +A ET+G+ + ICSDKTGTLT NRMTV + G T K P + Sbjct: 360 --EAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWT 417 Query: 503 ALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFV------LDLKR 556 AL+ +I L A+ A I +++ A G+ +E ALL + + R Sbjct: 418 ALS-RIAGLCNRAVF--KAGQENISVSKRDTA-----GDASESALLKCIELSCGSVRKMR 469 Query: 557 DFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDG--GFRLFSKGASEILLKKCTNILN 614 D P +IP FNS K ++ D L KGA E +L +C+ IL Sbjct: 470 DRNPKVAEIP---------FNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILV 520 Query: 615 SNGELRGFRPRDRD--DMVRKIIEPMACDGLRTICIAYRDFSAGQEP-----DWDNENEV 667 E+ P D++ D + + G R + + +G+ P D D N Sbjct: 521 QGKEI----PLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFP 576 Query: 668 VGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGED 727 L + ++ + DP R VP+A+ KC+ AGI V MVTGD+ TA+AIA GII G + Sbjct: 577 TEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNE 636 Query: 728 F-------LCLEGKEFNRRIR-------NEKGEIEQERLDKVWPKLR--VLARSSPTDKH 771 L + + N R ++ ++ E+LD++ V AR+SP K Sbjct: 637 TVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKL 696 Query: 772 TLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDN 831 +V+G Q +VAVTGDG ND PALKKAD+G AMGI+G+DV+K+A+D+IL DDN Sbjct: 697 IIVEG-----CQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDN 751 Query: 832 FTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIM 891 F SIV V GR ++D++ K + + LT N+ + PL V +L ++L Sbjct: 752 FASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGT 811 Query: 892 DTFASLALATEPPTESLLLRKP 913 D +++LA E ++ R+P Sbjct: 812 DMVPAISLAYEAAESDIMKRQP 833 >gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapiens] Length = 992 Score = 232 bits (591), Expect = 2e-60 Identities = 194/621 (31%), Positives = 307/621 (49%), Gaps = 67/621 (10%) Query: 358 SVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKF 417 S L+G T +A +I +++ + V + V +F++ ++ TWL Sbjct: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILS--LILEYTWLEAV----------I 291 Query: 418 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 477 F+IG+ +V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGT Sbjct: 292 FLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 349 Query: 478 LTTNRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVH---AISINSAYTTKILPPEKEGA 534 LT NRMTV + D E + D A+S + + + + Sbjct: 350 LTQNRMTVAHMWF-DNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQEN 408 Query: 535 LP----RQVGNKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMP 590 LP G+ +E ALL + + +RE+ K+ ++ FNS K ++ + P Sbjct: 409 LPILKRAVAGDASESALLKCIELCCGSVKEMRERYA--KIVEI-PFNSTNKYQLSIHKNP 465 Query: 591 DGG---FRLFSKGASEILLKKCTNILNSNGELRGFRPRDRD--DMVRKIIEPMACDGLRT 645 + L KGA E +L +C++IL E +P D + D + + G R Sbjct: 466 NTSEPQHLLVMKGAPERILDRCSSILLHGKE----QPLDEELKDAFQNAYLELGGLGERV 521 Query: 646 ICIAY-----RDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGIT 700 + + F G + D D+ N + +L + ++ + DP R VP+A+ KC+ AGI Sbjct: 522 LGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIK 581 Query: 701 VRMVTGDNINTARAIAAKCGIIQPGEDF-------LCLEGKEFNRRIR-------NEKGE 746 V MVTGD+ TA+AIA GII G + L + + N R ++ + Sbjct: 582 VIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKD 641 Query: 747 IEQERLDKV--WPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQ--VVAVTGDGTNDGPAL 802 + E+LD + + V AR+SP K +V+G QRQ +VAVTGDG ND PAL Sbjct: 642 MTSEQLDDILKYHTEIVFARTSPQQKLIIVEGC-------QRQGAIVAVTGDGVNDSPAL 694 Query: 803 KKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVV 862 KKAD+G AMGIAG+DV+K+A+D+IL DDNF SIV V GR ++D++ K + + LT N+ Sbjct: 695 KKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIP 754 Query: 863 AVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLIS 922 + PL V +L ++L D +++LA E ++ R+P P Sbjct: 755 EITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQP---RNPKTD 811 Query: 923 RTMMKNILGHAVYQLAIIFTL 943 + + + ++ A Q+ +I L Sbjct: 812 KLVNERLISMAYGQIGMIQAL 832 Score = 72.0 bits (175), Expect = 3e-12 Identities = 48/141 (34%), Positives = 80/141 (56%), Gaps = 10/141 (7%) Query: 160 ILLSVICVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVIRNGQLLQVPVAALVVGDIAQ 218 ++LS + V++ F+ + + K + ++S + Q+ VIRNG+ + + +VVGD+ + Sbjct: 103 VVLSAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVE 161 Query: 219 VKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSAD---KDPM-----LLSGTHVMEG 270 VK GD +PAD +I AN K+D SSLTGES+ +S D ++P+ T+ +EG Sbjct: 162 VKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEG 221 Query: 271 SGRMVVTAVGVNSQTGIIFTL 291 + R +V G + G I TL Sbjct: 222 TARGIVVYTGDRTVMGRIATL 242 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.135 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 46,778,792 Number of Sequences: 37866 Number of extensions: 2139496 Number of successful extensions: 8653 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 76 Number of HSP's successfully gapped in prelim test: 38 Number of HSP's that attempted gapping in prelim test: 8051 Number of HSP's gapped (non-prelim): 452 length of query: 1220 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1106 effective length of database: 13,930,794 effective search space: 15407458164 effective search space used: 15407458164 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.