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Search of human proteins with 48255945
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
sapiens]
(1220 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 2418 0.0
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 2226 0.0
gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap... 1980 0.0
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 1977 0.0
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 1967 0.0
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 1840 0.0
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 1837 0.0
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 1776 0.0
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 302 1e-81
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 302 1e-81
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 302 1e-81
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 302 1e-81
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom... 302 1e-81
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom... 302 1e-81
gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom... 302 1e-81
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 293 9e-79
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [... 293 9e-79
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H... 289 1e-77
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [... 289 1e-77
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 268 3e-71
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 268 3e-71
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 268 3e-71
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 261 3e-69
gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ... 256 7e-68
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 249 1e-65
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ... 248 3e-65
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 236 1e-61
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi... 236 1e-61
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] 236 1e-61
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 230 5e-60
>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
sapiens]
Length = 1220
Score = 2418 bits (6267), Expect = 0.0
Identities = 1220/1220 (100%), Positives = 1220/1220 (100%)
Query: 1 MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGIC 60
MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGIC
Sbjct: 1 MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGIC 60
Query: 61 TKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIV 120
TKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIV
Sbjct: 61 TKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIV 120
Query: 121 SLGLSFYQPPEGDNALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQ 180
SLGLSFYQPPEGDNALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQ
Sbjct: 121 SLGLSFYQPPEGDNALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQ 180
Query: 181 FRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDE 240
FRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDE
Sbjct: 181 FRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDE 240
Query: 241 SSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEK 300
SSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEK
Sbjct: 241 SSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEK 300
Query: 301 KDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKS 360
KDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKS
Sbjct: 301 KDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKS 360
Query: 361 VLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFF 420
VLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFF
Sbjct: 361 VLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFF 420
Query: 421 IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 480
IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL
Sbjct: 421 IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 480
Query: 481 TMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGLPRH 540
TMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGLPRH
Sbjct: 481 TMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGLPRH 540
Query: 541 VGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFS 600
VGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFS
Sbjct: 541 VGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFS 600
Query: 601 KGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEP 660
KGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEP
Sbjct: 601 KGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEP 660
Query: 661 EPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIAT 720
EPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIAT
Sbjct: 661 EPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIAT 720
Query: 721 KCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGI 780
KCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGI
Sbjct: 721 KCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGI 780
Query: 781 IDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVK 840
IDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVK
Sbjct: 781 IDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVK 840
Query: 841 AVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASL 900
AVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASL
Sbjct: 841 AVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASL 900
Query: 901 ALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGR 960
ALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGR
Sbjct: 901 ALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGR 960
Query: 961 NAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVVQ 1020
NAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVVQ
Sbjct: 961 NAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVVQ 1020
Query: 1021 IIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEE 1080
IIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEE
Sbjct: 1021 IIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEE 1080
Query: 1081 IPEEELAEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVNAFRSSLYEGLEKPESRSS 1140
IPEEELAEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVNAFRSSLYEGLEKPESRSS
Sbjct: 1081 IPEEELAEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVNAFRSSLYEGLEKPESRSS 1140
Query: 1141 IHNFMTHPEFRIEDSEPHIPLIDDTDAEDDAPTKRNSSPPPSPNKNNNAVDSGIHLTIEM 1200
IHNFMTHPEFRIEDSEPHIPLIDDTDAEDDAPTKRNSSPPPSPNKNNNAVDSGIHLTIEM
Sbjct: 1141 IHNFMTHPEFRIEDSEPHIPLIDDTDAEDDAPTKRNSSPPPSPNKNNNAVDSGIHLTIEM 1200
Query: 1201 NKSATSSSPGSPLHSLETSL 1220
NKSATSSSPGSPLHSLETSL
Sbjct: 1201 NKSATSSSPGSPLHSLETSL 1220
>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
sapiens]
Length = 1176
Score = 2226 bits (5769), Expect = 0.0
Identities = 1129/1149 (98%), Positives = 1137/1149 (98%), Gaps = 2/1149 (0%)
Query: 1 MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGIC 60
MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGIC
Sbjct: 1 MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGIC 60
Query: 61 TKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIV 120
TKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIV
Sbjct: 61 TKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIV 120
Query: 121 SLGLSFYQPPEGDNALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQ 180
SLGLSFYQPPEGDNALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQ
Sbjct: 121 SLGLSFYQPPEGDNALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQ 180
Query: 181 FRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDE 240
FRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDE
Sbjct: 181 FRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDE 240
Query: 241 SSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEK 300
SSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEK
Sbjct: 241 SSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEK 300
Query: 301 KDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKS 360
KDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKS
Sbjct: 301 KDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKS 360
Query: 361 VLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFF 420
VLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFF
Sbjct: 361 VLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFF 420
Query: 421 IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 480
IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL
Sbjct: 421 IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL 480
Query: 481 TMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGLPRH 540
TMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGLPRH
Sbjct: 481 TMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGLPRH 540
Query: 541 VGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFS 600
VGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFS
Sbjct: 541 VGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFS 600
Query: 601 KGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEP 660
KGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEP
Sbjct: 601 KGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEP 660
Query: 661 EPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIAT 720
EPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIAT
Sbjct: 661 EPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIAT 720
Query: 721 KCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGI 780
KCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGI
Sbjct: 721 KCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGI 780
Query: 781 IDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVK 840
IDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVK
Sbjct: 781 IDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVK 840
Query: 841 AVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASL 900
AVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASL
Sbjct: 841 AVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASL 900
Query: 901 ALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGR 960
ALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGR
Sbjct: 901 ALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGR 960
Query: 961 NAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVVQ 1020
NAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVVQ
Sbjct: 961 NAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVVQ 1020
Query: 1021 IIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEE 1080
IIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEE
Sbjct: 1021 IIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEE 1080
Query: 1081 IPEEELAEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVNAFR--SSLYEGLEKPESR 1138
IPEEELAEDVEEIDHAERELRRGQILWFRGLNRIQTQ+ VVNAF+ SS+ L + S
Sbjct: 1081 IPEEELAEDVEEIDHAERELRRGQILWFRGLNRIQTQMDVVNAFQSGSSIQGALRRQPSI 1140
Query: 1139 SSIHNFMTH 1147
+S H+ +T+
Sbjct: 1141 ASQHHDVTN 1149
>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sapiens]
Length = 1243
Score = 1980 bits (5130), Expect = 0.0
Identities = 996/1249 (79%), Positives = 1103/1249 (88%), Gaps = 35/1249 (2%)
Query: 1 MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGIC 60
MGDM N+ YS KN E++H G+FG T+ ELR+LMELR T+A+ KI+E+YGD IC
Sbjct: 1 MGDMTNSDF-YS--KNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAIC 57
Query: 61 TKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIV 120
+LKTSP EGL G DLE+R+ +FG+NFIPPKKPKTFLQLVWEALQDVTLIILEIAAI+
Sbjct: 58 RRLKTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAII 117
Query: 121 SLGLSFYQPPEGDNALCGEVSVG-EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEK 179
SLGLSFY PP N C G E+EGE E GWIEGAAILLSV+CVVLVTAFNDWSKEK
Sbjct: 118 SLGLSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 177
Query: 180 QFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKID 239
QFRGLQSRIEQEQKFTV+R GQV+QIPVA+I VGDIAQVKYGDLLPADG+ IQGNDLKID
Sbjct: 178 QFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKID 237
Query: 240 ESSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 299
ESSLTGESD V+KS+DKDP+LLSGTHVMEGSGRM+VTAVGVNSQTGIIFTLLGAGGEEEE
Sbjct: 238 ESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEE 297
Query: 300 KKDEKKKEK--------------------------KNKKQDGAIE-NRNKAKAQDGAA-M 331
KKD+K +K K QDG ++ +++KAK QDGAA M
Sbjct: 298 KKDKKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAM 357
Query: 332 EMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQGKLTKLAVQIGKAGLLMSAITVIILVLY 391
EMQPLKS EGGD D D+KKA++ KKEKSVLQGKLTKLAVQIGKAGL+MSAITVIILVLY
Sbjct: 358 EMQPLKSAEGGDAD--DRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLY 415
Query: 392 FVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM 451
F +DTF V K+PWL ECTP+Y+QYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM
Sbjct: 416 FTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM 475
Query: 452 KDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEPEAIPPNIL 511
KDNNLVRHLDACETMGNATAICSDKTGTLT NRMTVVQAY+ + HYK++P+P +I +
Sbjct: 476 KDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTM 535
Query: 512 SYLVTGISVNCAYTSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEA 571
L+ I++N AYT+KILPPEKEG LPR VGNKTEC LLG +LDLK+DY+ VR+++PEE
Sbjct: 536 ELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEK 595
Query: 572 LYKVYTFNSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDD 631
LYKVYTFNSVRKSMSTV+K D S+R++SKGASEI+LKKC KIL+ GE +VFRPRDRD+
Sbjct: 596 LYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDE 655
Query: 632 IVKTVIEPMASEGLRTICLAFRDFPAGEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVP 691
+VK VIEPMA +GLRTIC+A+RDFP+ PEP+WDNENDI+ LTCI VVGIEDPVRPEVP
Sbjct: 656 MVKKVIEPMACDGLRTICVAYRDFPSS-PEPDWDNENDILNELTCICVVGIEDPVRPEVP 714
Query: 692 DAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIRNEKGEIE 751
+AI+KCQRAGITVRMVTGDNINTARAIA KCGI+HPGEDFLCLEGK+FNRRIRNEKGEIE
Sbjct: 715 EAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIE 774
Query: 752 QERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGDGTNDGPALKKADVG 811
QERIDKIWPKLRVLARSSPTDKHTLVKGIIDST ++QRQVVAVTGDGTNDGPALKKADVG
Sbjct: 775 QERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVG 834
Query: 812 FAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAF 871
FAMGIAGTDVAKEASDIILTDDNF+SIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAF
Sbjct: 835 FAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAF 894
Query: 872 TGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLISRTMMKN 931
TGACITQDSPLKAVQMLWVNLIMDT ASLALATEPPTE+LLLRKPYGRNKPLISRTMMKN
Sbjct: 895 TGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKN 954
Query: 932 ILGHAFYQLVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTIVFNTFVLMQLFNEINAR 991
ILGHA YQL ++FTLLF GEK F IDSGRNAPLH+PPSEHYTI+FNTFV+MQLFNEINAR
Sbjct: 955 ILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINAR 1014
Query: 992 KIHGERNVFEGIFNNAIFCTIVLGTFVVQIIIVQFGGKPFSCSELSIEQWLWSIFLGMGT 1051
KIHGERNVF+GIF N IFCTIVLGTF +QI+IVQFGGKPFSCS L ++QW+W IF+G+G
Sbjct: 1015 KIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGE 1074
Query: 1052 LLWGQLISTIPTSRLKFLKEAGHGTQKEEIPEEELAEDVEEIDHAERELRRGQILWFRGL 1111
L+WGQ+I+TIPTSRLKFLKEAG TQKEEIPEEEL EDVEEIDHAERELRRGQILWFRGL
Sbjct: 1075 LVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGL 1134
Query: 1112 NRIQTQIRVVNAFRSSLYEGLEKPESRSSIHNFMTHPEFRIEDSEPHIPLIDDTDAEDDA 1171
NRIQTQIRVV AFRSSLYEGLEKPESR+SIHNFM HPEFRIEDS+PHIPLIDDTD E+DA
Sbjct: 1135 NRIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDA 1194
Query: 1172 PTKRNSSPPPSPNKNNNAVDSGIHLTIEMNKSATSSSPGSPLHSLETSL 1220
K+NSSPP S NKNN+A+DSGI+LT + +KSATSSSPGSP+HSLETSL
Sbjct: 1195 ALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL 1243
>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens]
Length = 1198
Score = 1977 bits (5122), Expect = 0.0
Identities = 991/1221 (81%), Positives = 1092/1221 (89%), Gaps = 24/1221 (1%)
Query: 1 MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGIC 60
MGDM N+ YS KN E++H G+FG T+ ELR+LMELR T+A+ KI+E+YGD IC
Sbjct: 1 MGDMTNSDF-YS--KNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAIC 57
Query: 61 TKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIV 120
+LKTSP EGL G DLE+R+ +FG+NFIPPKKPKTFLQLVWEALQDVTLIILEIAAI+
Sbjct: 58 RRLKTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAII 117
Query: 121 SLGLSFYQPPEGDNALCGEVSVG-EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEK 179
SLGLSFY PP N C G E+EGE E GWIEGAAILLSV+CVVLVTAFNDWSKEK
Sbjct: 118 SLGLSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 177
Query: 180 QFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKID 239
QFRGLQSRIEQEQKFTV+R GQV+QIPVA+I VGDIAQVKYGDLLPADG+ IQGNDLKID
Sbjct: 178 QFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKID 237
Query: 240 ESSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 299
ESSLTGESD V+KS+DKDP+LLSGTHVMEGSGRM+VTAVGVNSQTGIIFTLLGAGGEEEE
Sbjct: 238 ESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEE 297
Query: 300 KKDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEK 359
KKD KK K+QDGA AAMEMQPLKS EGGD D D+KKA++ KKEK
Sbjct: 298 KKD-----KKAKQQDGA------------AAMEMQPLKSAEGGDAD--DRKKASMHKKEK 338
Query: 360 SVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKF 419
SVLQGKLTKLAVQIGKAGL+MSAITVIILVLYF +DTF V K+PWL ECTP+Y+QYFVKF
Sbjct: 339 SVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKF 398
Query: 420 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 479
FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT
Sbjct: 399 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 458
Query: 480 LTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGLPR 539
LT NRMTVVQAY+ + HYK++P+P +I + L+ I++N AYT+KILPPEKEG LPR
Sbjct: 459 LTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPR 518
Query: 540 HVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIF 599
VGNKTEC LLG +LDLK+DY+ VR+++PEE LYKVYTFNSVRKSMSTV+K D S+R++
Sbjct: 519 QVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMY 578
Query: 600 SKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGE 659
SKGASEI+LKKC KIL+ GE +VFRPRDRD++VK VIEPMA +GLRTIC+A+RDFP+
Sbjct: 579 SKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSS- 637
Query: 660 PEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIA 719
PEP+WDNENDI+ LTCI VVGIEDPVRPEVP+AI+KCQRAGITVRMVTGDNINTARAIA
Sbjct: 638 PEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIA 697
Query: 720 TKCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKG 779
KCGI+HPGEDFLCLEGK+FNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKG
Sbjct: 698 IKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKG 757
Query: 780 IIDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIV 839
IIDST ++QRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNF+SIV
Sbjct: 758 IIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIV 817
Query: 840 KAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLAS 899
KAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDT AS
Sbjct: 818 KAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFAS 877
Query: 900 LALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSG 959
LALATEPPTE+LLLRKPYGRNKPLISRTMMKNILGHA YQL ++FTLLF GEK F IDSG
Sbjct: 878 LALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSG 937
Query: 960 RNAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVV 1019
RNAPLH+PPSEHYTI+FNTFV+MQLFNEINARKIHGERNVF+GIF N IFCTIVLGTF +
Sbjct: 938 RNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAI 997
Query: 1020 QIIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKE 1079
QI+IVQFGGKPFSCS L ++QW+W IF+G+G L+WGQ+I+TIPTSRLKFLKEAG TQKE
Sbjct: 998 QIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKE 1057
Query: 1080 EIPEEELAEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVNAFRSSLYEGLEKPESRS 1139
EIPEEEL EDVEEIDHAERELRRGQILWFRGLNRIQTQIRVV AFRSSLYEGLEKPESR+
Sbjct: 1058 EIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRT 1117
Query: 1140 SIHNFMTHPEFRIEDSEPHIPLIDDTDAEDDAPTKRNSSPPPSPNKNNNAVDSGIHLTIE 1199
SIHNFM HPEFRIEDS+PHIPLIDDTD E+DA K+NSSPP S NKNN+A+DSGI+LT +
Sbjct: 1118 SIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTD 1177
Query: 1200 MNKSATSSSPGSPLHSLETSL 1220
+KSATSSSPGSP+HSLETSL
Sbjct: 1178 TSKSATSSSPGSPIHSLETSL 1198
>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
sapiens]
Length = 1220
Score = 1967 bits (5096), Expect = 0.0
Identities = 986/1227 (80%), Positives = 1097/1227 (89%), Gaps = 14/1227 (1%)
Query: 1 MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGIC 60
MGDMAN+S+ + ++ G FG TLAELR LMELR +AL+KI+E+YGDV G+C
Sbjct: 1 MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC 60
Query: 61 TKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIV 120
+LKTSP EGL+ N DLE+R ++G+NFIPPK+PKTFLQLVWEALQDVTLIILE+AAIV
Sbjct: 61 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV 120
Query: 121 SLGLSFYQPPEGDNALCGEVSVG-EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEK 179
SLGLSFY PP ++ CG VS G E+EGE E GWIEGAAILLSV+CVVLVTAFNDWSKEK
Sbjct: 121 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 180
Query: 180 QFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKID 239
QFRGLQSRIEQEQKFTVIR GQ++Q+PVA + VGDIAQVKYGDLLPADG+LIQ NDLKID
Sbjct: 181 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID 240
Query: 240 ESSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 299
ESSLTGESDHV+KS DKDP+LLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE
Sbjct: 241 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 300
Query: 300 KKDEKKKEKKNKKQDGAIEN-RNKAKAQDGA-AMEMQPLKSEEGGDGDEKDKKKANLPKK 357
KKD KK K+QDGA+E+ + KAK QDGA AMEMQPLKS EGG+ +E++KKKAN PKK
Sbjct: 301 KKD-----KKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKK 355
Query: 358 EKSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFV 417
EKSVLQGKLTKLAVQIGKAGL+MSAITVIILVLYFVI+TF V+ R WLAECTP+Y+QYFV
Sbjct: 356 EKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFV 415
Query: 418 KFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKT 477
KFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKT
Sbjct: 416 KFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKT 475
Query: 478 GTLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGL 537
GTLT NRMTVVQ+Y+ + HYK++P P A+ P IL LV IS+N AYT+KILPPEKEG L
Sbjct: 476 GTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGAL 535
Query: 538 PRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYR 597
PR VGNKTECALLG +LDLKRD+Q VR +IPE+ LYKVYTFNSVRKSMSTV++ DG +R
Sbjct: 536 PRQVGNKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFR 595
Query: 598 IFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPA 657
+FSKGASEI+LKKC IL++NGE + FRPRDRDD+V+ +IEPMA +GLRTIC+A+RDF A
Sbjct: 596 LFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSA 655
Query: 658 GEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARA 717
G+ EP+WDNEN++V LTCIAVVGIEDPVRPEVP+AI+KCQRAGITVRMVTGDNINTARA
Sbjct: 656 GQ-EPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARA 714
Query: 718 IATKCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLV 777
IA KCGI+ PGEDFLCLEGK+FNRRIRNEKGEIEQER+DK+WPKLRVLARSSPTDKHTLV
Sbjct: 715 IAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLV 774
Query: 778 KGIIDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTS 837
KGIIDST +QRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTS
Sbjct: 775 KGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTS 834
Query: 838 IVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTL 897
IVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDT
Sbjct: 835 IVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTF 894
Query: 898 ASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDID 957
ASLALATEPPTESLLLRKPYGR+KPLISRTMMKNILGHA YQL ++FTLLF GE FFDID
Sbjct: 895 ASLALATEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDID 954
Query: 958 SGRNAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTF 1017
SGRNAPLH+PPSEHYTI+FNTFV+MQLFNEINARKIHGERNVF+GIF+N IFCTIVLGTF
Sbjct: 955 SGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTF 1014
Query: 1018 VVQIIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQ 1077
+QI+IVQFGGKPFSCS LS EQWLW +F+G+G L+WGQ+I+TIPTS+LK LKEAGHG
Sbjct: 1015 GIQIVIVQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPG 1074
Query: 1078 KEEIPEEELAEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVNAFRSSLYEGLEKPES 1137
K+E+ +EELAE EEIDHAERELRRGQILWFRGLNRIQTQIRVV AFRSSLYEGLEKPES
Sbjct: 1075 KDEMTDEELAEGEEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPES 1134
Query: 1138 RSSIHNFMTHPEFRIEDSEPHIPLIDDTDAEDDAPTKRNSSPPPSPNKNNNAVDSGIHLT 1197
++SIHNFM PEF I D +IPLIDDTD +++ R + PPPSPN+NNNA+DSGI+LT
Sbjct: 1135 KTSIHNFMATPEFLINDYTHNIPLIDDTDVDENEERLR-APPPPSPNQNNNAIDSGIYLT 1193
Query: 1198 IEMNKSAT----SSSPGSPLHSLETSL 1220
+ KSAT SSSPGSPLHS+ETSL
Sbjct: 1194 THVTKSATSSVFSSSPGSPLHSVETSL 1220
>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
sapiens]
Length = 1173
Score = 1840 bits (4765), Expect = 0.0
Identities = 917/1130 (81%), Positives = 1019/1130 (90%), Gaps = 9/1130 (0%)
Query: 1 MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGIC 60
MGDMAN+S+ + ++ G FG TLAELR LMELR +AL+KI+E+YGDV G+C
Sbjct: 1 MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC 60
Query: 61 TKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIV 120
+LKTSP EGL+ N DLE+R ++G+NFIPPK+PKTFLQLVWEALQDVTLIILE+AAIV
Sbjct: 61 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV 120
Query: 121 SLGLSFYQPPEGDNALCGEVSVG-EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEK 179
SLGLSFY PP ++ CG VS G E+EGE E GWIEGAAILLSV+CVVLVTAFNDWSKEK
Sbjct: 121 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 180
Query: 180 QFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKID 239
QFRGLQSRIEQEQKFTVIR GQ++Q+PVA + VGDIAQVKYGDLLPADG+LIQ NDLKID
Sbjct: 181 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID 240
Query: 240 ESSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 299
ESSLTGESDHV+KS DKDP+LLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE
Sbjct: 241 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 300
Query: 300 KKDEKKKEKKNKKQDGAIEN-RNKAKAQDGA-AMEMQPLKSEEGGDGDEKDKKKANLPKK 357
KKD KK K+QDGA+E+ + KAK QDGA AMEMQPLKS EGG+ +E++KKKAN PKK
Sbjct: 301 KKD-----KKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKK 355
Query: 358 EKSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFV 417
EKSVLQGKLTKLAVQIGKAGL+MSAITVIILVLYFVI+TF V+ R WLAECTP+Y+QYFV
Sbjct: 356 EKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFV 415
Query: 418 KFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKT 477
KFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKT
Sbjct: 416 KFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKT 475
Query: 478 GTLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGL 537
GTLT NRMTVVQ+Y+ + HYK++P P A+ P IL LV IS+N AYT+KILPPEKEG L
Sbjct: 476 GTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGAL 535
Query: 538 PRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYR 597
PR VGNKTECALLG +LDLKRD+Q VR +IPE+ LYKVYTFNSVRKSMSTV++ DG +R
Sbjct: 536 PRQVGNKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFR 595
Query: 598 IFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPA 657
+FSKGASEI+LKKC IL++NGE + FRPRDRDD+V+ +IEPMA +GLRTIC+A+RDF A
Sbjct: 596 LFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSA 655
Query: 658 GEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARA 717
G+ EP+WDNEN++V LTCIAVVGIEDPVRPEVP+AI+KCQRAGITVRMVTGDNINTARA
Sbjct: 656 GQ-EPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARA 714
Query: 718 IATKCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLV 777
IA KCGI+ PGEDFLCLEGK+FNRRIRNEKGEIEQER+DK+WPKLRVLARSSPTDKHTLV
Sbjct: 715 IAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLV 774
Query: 778 KGIIDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTS 837
KGIIDST +QRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTS
Sbjct: 775 KGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTS 834
Query: 838 IVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTL 897
IVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDT
Sbjct: 835 IVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTF 894
Query: 898 ASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDID 957
ASLALATEPPTESLLLRKPYGR+KPLISRTMMKNILGHA YQL ++FTLLF GE FFDID
Sbjct: 895 ASLALATEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDID 954
Query: 958 SGRNAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTF 1017
SGRNAPLH+PPSEHYTI+FNTFV+MQLFNEINARKIHGERNVF+GIF+N IFCTIVLGTF
Sbjct: 955 SGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTF 1014
Query: 1018 VVQIIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQ 1077
+QI+IVQFGGKPFSCS LS EQWLW +F+G+G L+WGQ+I+TIPTS+LK LKEAGHG
Sbjct: 1015 GIQIVIVQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPG 1074
Query: 1078 KEEIPEEELAEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVNAFRSS 1127
K+E+ +EELAE EEIDHAERELRRGQILWFRGLNRIQTQ+ VV+ F+ S
Sbjct: 1075 KDEMTDEELAEGEEEIDHAERELRRGQILWFRGLNRIQTQMEVVSTFKRS 1124
>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
sapiens]
Length = 1205
Score = 1837 bits (4758), Expect = 0.0
Identities = 928/1214 (76%), Positives = 1044/1214 (85%), Gaps = 29/1214 (2%)
Query: 16 NSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGICTKLKTSPNEGLSGNP 75
NS+ E+ +GDFG T+ ELR LMELRS DAL +I YG V +C++LKTSP EGLSGNP
Sbjct: 12 NSMAESR-EGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNP 70
Query: 76 ADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGDNA 135
ADLE+R VFG N IPPKKPKTFL+LVWEALQDVTLIILEIAAI+SL LSFY+P +N
Sbjct: 71 ADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENE 130
Query: 136 LCGEVSVG-EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKF 194
LCG+V+ E+E E + GWIEGAAIL SV+ VVLVTAFNDWSKEKQFRGLQ RIEQEQKF
Sbjct: 131 LCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKF 190
Query: 195 TVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSL 254
++IR GQ+IQ+PVA+I VGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSL
Sbjct: 191 SIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSL 250
Query: 255 DKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKKKEKKNKKQD 314
DKDP+LLSGTHVMEGSGRMVVTAVGVNSQTGII TLLG + DE +K+KK KKQ
Sbjct: 251 DKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED-----DEGEKKKKGKKQ- 304
Query: 315 GAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQGKLTKLAVQIG 374
G ENRNKAK QDG A+E+QPL S+EG D +EKDKK +PKKEKSVLQGKLT+LAVQIG
Sbjct: 305 GVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIG 364
Query: 375 KAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEG 434
KAGLLMSA+TV IL+LYFVID F + +RPWL ECTPIYIQYFVKFFIIG+TVLVVAVPEG
Sbjct: 365 KAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEG 424
Query: 435 LPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINE 494
LPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYI
Sbjct: 425 LPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGG 484
Query: 495 KHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGLPRHVGNKTECALLGLLL 554
HY+++P P+ P +L +V GIS+N AYTSKILPPEKEGGLPR VGNKTECALLG +
Sbjct: 485 IHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVT 544
Query: 555 DLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFKI 614
DLK+DYQ VRNE+PEE LYKVYTFNSVRKSMSTV++N +G +R++SKGASEIIL+KC +I
Sbjct: 545 DLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRI 604
Query: 615 LSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEWDNENDIVTGL 674
L GEA F+ +DRDD+V+TVIEPMA +GLRTIC+A+RDF + EP WDNEN+I+T L
Sbjct: 605 LDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFD--DTEPSWDNENEILTEL 662
Query: 675 TCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCL 734
TCIAVVGIEDPVRPEVPDAI KC++AGITVRMVTGDNINTARAIATKCGIL PG+DFLCL
Sbjct: 663 TCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCL 722
Query: 735 EGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAV 794
EGK+FNR IRNEKGE+EQE++DKIWPKLRVLARSSPTDKHTLVKGIIDSTV + RQVVAV
Sbjct: 723 EGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAV 782
Query: 795 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK 854
TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK
Sbjct: 783 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK 842
Query: 855 FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLR 914
FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDT ASLALATEPPTESLL R
Sbjct: 843 FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKR 902
Query: 915 KPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTI 974
+PYGRNKPLISRTMMKNILGHAFYQL+V+F L+FAGEKFFDIDSGR APLH+PPS+HYTI
Sbjct: 903 RPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTI 962
Query: 975 VFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVVQIIIVQFGGKPFSCS 1034
VFNTFVLMQLFNEIN+RKIHGE+NVF GI+ N IFC++VLGTF+ QI IV+FGGKPFSC+
Sbjct: 963 VFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCT 1022
Query: 1035 ELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEEIPEEELAEDVEEID 1094
LS+ QWLW +F+G+G LLWGQ IS IPT LKFLKEAGHGT KEEI ++ AE ++EID
Sbjct: 1023 SLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKD--AEGLDEID 1080
Query: 1095 HAERELRRGQILWFRGLNRIQTQIRVVNAFRSSLYEGLEKPESRSSIHNFMTHPEFRIED 1154
HAE ELRRGQILWFRGLNRIQTQI+VV AF SSL+E ++KP ++ SIH+FMTHPEF IE+
Sbjct: 1081 HAEMELRRGQILWFRGLNRIQTQIKVVKAFHSSLHESIQKPYNQKSIHSFMTHPEFAIEE 1140
Query: 1155 SEPHIPLIDDTDAEDDAPTKR--------NSSPPPSPNKNNNAVDSGIHLTIEMNKSATS 1206
P PL+D+ + E+ + + P N NNNAVD +++ +S +S
Sbjct: 1141 ELPRTPLLDEEEEENPDKASKFGTRVLLLDGEVTPYANTNNNAVDCN---QVQLPQSDSS 1197
Query: 1207 SSPGSPLHSLETSL 1220
L SLETS+
Sbjct: 1198 ------LQSLETSV 1205
>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
sapiens]
Length = 1170
Score = 1776 bits (4599), Expect = 0.0
Identities = 900/1184 (76%), Positives = 1015/1184 (85%), Gaps = 35/1184 (2%)
Query: 16 NSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGICTKLKTSPNEGLSGNP 75
NS+ E+ +GDFG T+ ELR LMELRS DAL +I YG V +C++LKTSP EGLSGNP
Sbjct: 12 NSMAESR-EGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNP 70
Query: 76 ADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGDNA 135
ADLE+R VFG N IPPKKPKTFL+LVWEALQDVTLIILEIAAI+SL LSFY+P +N
Sbjct: 71 ADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENE 130
Query: 136 LCGEVSVG-EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKF 194
LCG+V+ E+E E + GWIEGAAIL SV+ VVLVTAFNDWSKEKQFRGLQ RIEQEQKF
Sbjct: 131 LCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKF 190
Query: 195 TVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSL 254
++IR GQ+IQ+PVA+I VGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSL
Sbjct: 191 SIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSL 250
Query: 255 DKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKKKEKKNKKQD 314
DKDP+LLSGTHVMEGSGRMVVTAVGVNSQTGII TLLG + DE +K+KK KKQ
Sbjct: 251 DKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED-----DEGEKKKKGKKQ- 304
Query: 315 GAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQGKLTKLAVQIG 374
G ENRNKAK QDG A+E+QPL S+EG D +EKDKK +PKKEKSVLQGKLT+LAVQIG
Sbjct: 305 GVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIG 364
Query: 375 KAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEG 434
KAGLLMSA+TV IL+LYFVID F + +RPWL ECTPIYIQYFVKFFIIG+TVLVVAVPEG
Sbjct: 365 KAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEG 424
Query: 435 LPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINE 494
LPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYI
Sbjct: 425 LPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGG 484
Query: 495 KHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGLPRHVGNKTECALLGLLL 554
HY+++P P+ P +L +V GIS+N AYTSKILPPEKEGGLPR VGNKTECALLG +
Sbjct: 485 IHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVT 544
Query: 555 DLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFKI 614
DLK+DYQ VRNE+PEE LYKVYTFNSVRKSMSTV++N +G +R++SKGASEIIL+KC +I
Sbjct: 545 DLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRI 604
Query: 615 LSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEWDNENDIVTGL 674
L GEA F+ +DRDD+V+TVIEPMA +GLRTIC+A+RDF + EP WDNEN+I+T L
Sbjct: 605 LDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFD--DTEPSWDNENEILTEL 662
Query: 675 TCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCL 734
TCIAVVGIEDPVRPEVPDAI KC++AGITVRMVTGDNINTARAIATKCGIL PG+DFLCL
Sbjct: 663 TCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCL 722
Query: 735 EGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAV 794
EGK+FNR IRNEKGE+EQE++DKIWPKLRVLARSSPTDKHTLVKGIIDSTV + RQVVAV
Sbjct: 723 EGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAV 782
Query: 795 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK 854
TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK
Sbjct: 783 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK 842
Query: 855 FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLR 914
FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDT ASLALATEPPTESLL R
Sbjct: 843 FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKR 902
Query: 915 KPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTI 974
+PYGRNKPLISRTMMKNILGHAFYQL+V+F L+FAGEKFFDIDSGR APLH+PPS+HYTI
Sbjct: 903 RPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTI 962
Query: 975 VFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVVQIIIVQFGGKPFSCS 1034
VFNTFVLMQLFNEIN+RKIHGE+NVF GI+ N IFC++VLGTF+ QI IV+FGGKPFSC+
Sbjct: 963 VFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCT 1022
Query: 1035 ELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEEIPEEELAEDVEEID 1094
LS+ QWLW +F+G+G LLWGQ IS IPT LKFLKEAGHGT KEEI ++ AE ++EID
Sbjct: 1023 SLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKD--AEGLDEID 1080
Query: 1095 HAERELRRGQILWFRGLNRIQTQIRVVNAFRS-SLYEGLEKPESRSSIHNFMTHPEFRIE 1153
HAE ELRRGQILWFRGLNRIQTQI V+N F++ + ++G+ + + N H + ++
Sbjct: 1081 HAEMELRRGQILWFRGLNRIQTQIDVINTFQTGASFKGVLRRQ------NMGQHLDVKLV 1134
Query: 1154 DSEPHIPLIDDTDAEDDAPTKRNS-------SPPPSPNKNNNAV 1190
S ++ + AP K + S PP N++ +V
Sbjct: 1135 PSSSYVAV---------APVKSSPTTSVPAVSSPPMGNQSGQSV 1169
>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
sapiens]
Length = 999
Score = 302 bits (774), Expect = 1e-81
Identities = 276/930 (29%), Positives = 422/930 (45%), Gaps = 176/930 (18%)
Query: 74 NPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGD 133
+PA + +G N +P ++ K+ +LV E +D+ + IL +AA+VS L+++
Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78
Query: 134 NALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQK 193
EE E T ++E I+L +V +V + + + E L+ + K
Sbjct: 79 ----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK 128
Query: 194 FTVIRGGQ--VIQIPVADITVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGESDH 249
VIR + V +I DI GDI +V GD +PAD LI+ L++D+S LTGES
Sbjct: 129 --VIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVS 186
Query: 250 VKK-----------SLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEE 298
V K + DK +L SGT++ G AVGV TG+ T LG
Sbjct: 187 VTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGL-HTELG------ 233
Query: 299 EKKDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKE 358
K + Q A+E E
Sbjct: 234 ----------KIRSQMAAVE--------------------------------------PE 245
Query: 359 KSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVK 418
++ LQ KL + Q+ A +S I V + V+ WL V
Sbjct: 246 RTPLQRKLDEFGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA--------VY 294
Query: 419 FFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTG 478
+F I V + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTG
Sbjct: 295 YFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTG 354
Query: 479 TLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGIS-------------VNCAY- 524
TLT N+M+V + ++ V E +A + + ++G + V C
Sbjct: 355 TLTTNQMSVCRMFV-------VAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQF 407
Query: 525 -------------TSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVR------- 564
L + G+ VG TE AL L+ + D++
Sbjct: 408 DGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVER 467
Query: 565 ----NEIPEEALYKVYT--FNSVRKSMSTVLK------NSDGSYRIFSKGASEIILKKCF 612
N + ++ + K +T F+ RKSMS GS ++F KGA E ++++C
Sbjct: 468 AGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGS-KMFVKGAPESVIERCS 526
Query: 613 KILSANGEAKVFRPRDRDDIVKTVIE-PMASEGLRTICLAFRDFPAGEPEPEWDNENDIV 671
+ + A + P R+ I+ + + S+ LR + LA RD P + + E D+ + V
Sbjct: 527 SVRVGSRTAPL-TPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFV 585
Query: 672 ---TGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPG 728
T LT + VG+ DP RPEV I +C +AGI V M+TGDN TA AI + GI
Sbjct: 586 QYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDT 645
Query: 729 EDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQ 788
ED + GK + R E ++ E+ + R AR P K +V+ +
Sbjct: 646 ED---VAGKAYTGR---EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSF 694
Query: 789 RQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNV 848
++ A+TGDG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +
Sbjct: 695 NEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAI 753
Query: 849 YDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPT 908
Y ++ +F+++ ++ NV V+ F A + L VQ+LWVNL+ D L + AL PP
Sbjct: 754 YSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPD 813
Query: 909 ESLLLRKPYGRNKPLISRTMMKNILGHAFY 938
++ + P + LIS + L Y
Sbjct: 814 LDIMEKLPRSPREALISGWLFFRYLAIGVY 843
>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 302 bits (774), Expect = 1e-81
Identities = 276/930 (29%), Positives = 422/930 (45%), Gaps = 176/930 (18%)
Query: 74 NPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGD 133
+PA + +G N +P ++ K+ +LV E +D+ + IL +AA+VS L+++
Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78
Query: 134 NALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQK 193
EE E T ++E I+L +V +V + + + E L+ + K
Sbjct: 79 ----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK 128
Query: 194 FTVIRGGQ--VIQIPVADITVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGESDH 249
VIR + V +I DI GDI +V GD +PAD LI+ L++D+S LTGES
Sbjct: 129 --VIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVS 186
Query: 250 VKK-----------SLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEE 298
V K + DK +L SGT++ G AVGV TG+ T LG
Sbjct: 187 VTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGL-HTELG------ 233
Query: 299 EKKDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKE 358
K + Q A+E E
Sbjct: 234 ----------KIRSQMAAVE--------------------------------------PE 245
Query: 359 KSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVK 418
++ LQ KL + Q+ A +S I V + V+ WL V
Sbjct: 246 RTPLQRKLDEFGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA--------VY 294
Query: 419 FFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTG 478
+F I V + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTG
Sbjct: 295 YFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTG 354
Query: 479 TLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGIS-------------VNCAY- 524
TLT N+M+V + ++ V E +A + + ++G + V C
Sbjct: 355 TLTTNQMSVCRMFV-------VAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQF 407
Query: 525 -------------TSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVR------- 564
L + G+ VG TE AL L+ + D++
Sbjct: 408 DGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVER 467
Query: 565 ----NEIPEEALYKVYT--FNSVRKSMSTVLK------NSDGSYRIFSKGASEIILKKCF 612
N + ++ + K +T F+ RKSMS GS ++F KGA E ++++C
Sbjct: 468 AGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGS-KMFVKGAPESVIERCS 526
Query: 613 KILSANGEAKVFRPRDRDDIVKTVIE-PMASEGLRTICLAFRDFPAGEPEPEWDNENDIV 671
+ + A + P R+ I+ + + S+ LR + LA RD P + + E D+ + V
Sbjct: 527 SVRVGSRTAPL-TPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFV 585
Query: 672 ---TGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPG 728
T LT + VG+ DP RPEV I +C +AGI V M+TGDN TA AI + GI
Sbjct: 586 QYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDT 645
Query: 729 EDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQ 788
ED + GK + R E ++ E+ + R AR P K +V+ +
Sbjct: 646 ED---VAGKAYTGR---EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSF 694
Query: 789 RQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNV 848
++ A+TGDG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +
Sbjct: 695 NEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAI 753
Query: 849 YDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPT 908
Y ++ +F+++ ++ NV V+ F A + L VQ+LWVNL+ D L + AL PP
Sbjct: 754 YSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPD 813
Query: 909 ESLLLRKPYGRNKPLISRTMMKNILGHAFY 938
++ + P + LIS + L Y
Sbjct: 814 LDIMEKLPRSPREALISGWLFFRYLAIGVY 843
>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
sapiens]
Length = 998
Score = 302 bits (774), Expect = 1e-81
Identities = 276/930 (29%), Positives = 422/930 (45%), Gaps = 176/930 (18%)
Query: 74 NPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGD 133
+PA + +G N +P ++ K+ +LV E +D+ + IL +AA+VS L+++
Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78
Query: 134 NALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQK 193
EE E T ++E I+L +V +V + + + E L+ + K
Sbjct: 79 ----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK 128
Query: 194 FTVIRGGQ--VIQIPVADITVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGESDH 249
VIR + V +I DI GDI +V GD +PAD LI+ L++D+S LTGES
Sbjct: 129 --VIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVS 186
Query: 250 VKK-----------SLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEE 298
V K + DK +L SGT++ G AVGV TG+ T LG
Sbjct: 187 VTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGL-HTELG------ 233
Query: 299 EKKDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKE 358
K + Q A+E E
Sbjct: 234 ----------KIRSQMAAVE--------------------------------------PE 245
Query: 359 KSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVK 418
++ LQ KL + Q+ A +S I V + V+ WL V
Sbjct: 246 RTPLQRKLDEFGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA--------VY 294
Query: 419 FFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTG 478
+F I V + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTG
Sbjct: 295 YFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTG 354
Query: 479 TLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGIS-------------VNCAY- 524
TLT N+M+V + ++ V E +A + + ++G + V C
Sbjct: 355 TLTTNQMSVCRMFV-------VAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQF 407
Query: 525 -------------TSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVR------- 564
L + G+ VG TE AL L+ + D++
Sbjct: 408 DGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVER 467
Query: 565 ----NEIPEEALYKVYT--FNSVRKSMSTVLK------NSDGSYRIFSKGASEIILKKCF 612
N + ++ + K +T F+ RKSMS GS ++F KGA E ++++C
Sbjct: 468 AGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGS-KMFVKGAPESVIERCS 526
Query: 613 KILSANGEAKVFRPRDRDDIVKTVIE-PMASEGLRTICLAFRDFPAGEPEPEWDNENDIV 671
+ + A + P R+ I+ + + S+ LR + LA RD P + + E D+ + V
Sbjct: 527 SVRVGSRTAPL-TPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFV 585
Query: 672 ---TGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPG 728
T LT + VG+ DP RPEV I +C +AGI V M+TGDN TA AI + GI
Sbjct: 586 QYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDT 645
Query: 729 EDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQ 788
ED + GK + R E ++ E+ + R AR P K +V+ +
Sbjct: 646 ED---VAGKAYTGR---EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSF 694
Query: 789 RQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNV 848
++ A+TGDG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +
Sbjct: 695 NEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAI 753
Query: 849 YDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPT 908
Y ++ +F+++ ++ NV V+ F A + L VQ+LWVNL+ D L + AL PP
Sbjct: 754 YSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPD 813
Query: 909 ESLLLRKPYGRNKPLISRTMMKNILGHAFY 938
++ + P + LIS + L Y
Sbjct: 814 LDIMEKLPRSPREALISGWLFFRYLAIGVY 843
>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 302 bits (774), Expect = 1e-81
Identities = 276/930 (29%), Positives = 422/930 (45%), Gaps = 176/930 (18%)
Query: 74 NPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGD 133
+PA + +G N +P ++ K+ +LV E +D+ + IL +AA+VS L+++
Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78
Query: 134 NALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQK 193
EE E T ++E I+L +V +V + + + E L+ + K
Sbjct: 79 ----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK 128
Query: 194 FTVIRGGQ--VIQIPVADITVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGESDH 249
VIR + V +I DI GDI +V GD +PAD LI+ L++D+S LTGES
Sbjct: 129 --VIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVS 186
Query: 250 VKK-----------SLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEE 298
V K + DK +L SGT++ G AVGV TG+ T LG
Sbjct: 187 VTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGL-HTELG------ 233
Query: 299 EKKDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKE 358
K + Q A+E E
Sbjct: 234 ----------KIRSQMAAVE--------------------------------------PE 245
Query: 359 KSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVK 418
++ LQ KL + Q+ A +S I V + V+ WL V
Sbjct: 246 RTPLQRKLDEFGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA--------VY 294
Query: 419 FFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTG 478
+F I V + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTG
Sbjct: 295 YFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTG 354
Query: 479 TLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGIS-------------VNCAY- 524
TLT N+M+V + ++ V E +A + + ++G + V C
Sbjct: 355 TLTTNQMSVCRMFV-------VAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQF 407
Query: 525 -------------TSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVR------- 564
L + G+ VG TE AL L+ + D++
Sbjct: 408 DGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVER 467
Query: 565 ----NEIPEEALYKVYT--FNSVRKSMSTVLK------NSDGSYRIFSKGASEIILKKCF 612
N + ++ + K +T F+ RKSMS GS ++F KGA E ++++C
Sbjct: 468 AGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGS-KMFVKGAPESVIERCS 526
Query: 613 KILSANGEAKVFRPRDRDDIVKTVIE-PMASEGLRTICLAFRDFPAGEPEPEWDNENDIV 671
+ + A + P R+ I+ + + S+ LR + LA RD P + + E D+ + V
Sbjct: 527 SVRVGSRTAPL-TPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFV 585
Query: 672 ---TGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPG 728
T LT + VG+ DP RPEV I +C +AGI V M+TGDN TA AI + GI
Sbjct: 586 QYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDT 645
Query: 729 EDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQ 788
ED + GK + R E ++ E+ + R AR P K +V+ +
Sbjct: 646 ED---VAGKAYTGR---EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSF 694
Query: 789 RQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNV 848
++ A+TGDG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +
Sbjct: 695 NEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAI 753
Query: 849 YDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPT 908
Y ++ +F+++ ++ NV V+ F A + L VQ+LWVNL+ D L + AL PP
Sbjct: 754 YSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPD 813
Query: 909 ESLLLRKPYGRNKPLISRTMMKNILGHAFY 938
++ + P + LIS + L Y
Sbjct: 814 LDIMEKLPRSPREALISGWLFFRYLAIGVY 843
>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
sapiens]
Length = 1043
Score = 302 bits (774), Expect = 1e-81
Identities = 276/930 (29%), Positives = 422/930 (45%), Gaps = 176/930 (18%)
Query: 74 NPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGD 133
+PA + +G N +P ++ K+ +LV E +D+ + IL +AA+VS L+++
Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78
Query: 134 NALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQK 193
EE E T ++E I+L +V +V + + + E L+ + K
Sbjct: 79 ----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK 128
Query: 194 FTVIRGGQ--VIQIPVADITVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGESDH 249
VIR + V +I DI GDI +V GD +PAD LI+ L++D+S LTGES
Sbjct: 129 --VIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVS 186
Query: 250 VKK-----------SLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEE 298
V K + DK +L SGT++ G AVGV TG+ T LG
Sbjct: 187 VTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGL-HTELG------ 233
Query: 299 EKKDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKE 358
K + Q A+E E
Sbjct: 234 ----------KIRSQMAAVE--------------------------------------PE 245
Query: 359 KSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVK 418
++ LQ KL + Q+ A +S I V + V+ WL V
Sbjct: 246 RTPLQRKLDEFGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA--------VY 294
Query: 419 FFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTG 478
+F I V + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTG
Sbjct: 295 YFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTG 354
Query: 479 TLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGIS-------------VNCAY- 524
TLT N+M+V + ++ V E +A + + ++G + V C
Sbjct: 355 TLTTNQMSVCRMFV-------VAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQF 407
Query: 525 -------------TSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVR------- 564
L + G+ VG TE AL L+ + D++
Sbjct: 408 DGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVER 467
Query: 565 ----NEIPEEALYKVYT--FNSVRKSMSTVLK------NSDGSYRIFSKGASEIILKKCF 612
N + ++ + K +T F+ RKSMS GS ++F KGA E ++++C
Sbjct: 468 AGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGS-KMFVKGAPESVIERCS 526
Query: 613 KILSANGEAKVFRPRDRDDIVKTVIE-PMASEGLRTICLAFRDFPAGEPEPEWDNENDIV 671
+ + A + P R+ I+ + + S+ LR + LA RD P + + E D+ + V
Sbjct: 527 SVRVGSRTAPL-TPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFV 585
Query: 672 ---TGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPG 728
T LT + VG+ DP RPEV I +C +AGI V M+TGDN TA AI + GI
Sbjct: 586 QYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDT 645
Query: 729 EDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQ 788
ED + GK + R E ++ E+ + R AR P K +V+ +
Sbjct: 646 ED---VAGKAYTGR---EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSF 694
Query: 789 RQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNV 848
++ A+TGDG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +
Sbjct: 695 NEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAI 753
Query: 849 YDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPT 908
Y ++ +F+++ ++ NV V+ F A + L VQ+LWVNL+ D L + AL PP
Sbjct: 754 YSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPD 813
Query: 909 ESLLLRKPYGRNKPLISRTMMKNILGHAFY 938
++ + P + LIS + L Y
Sbjct: 814 LDIMEKLPRSPREALISGWLFFRYLAIGVY 843
>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
sapiens]
Length = 1044
Score = 302 bits (774), Expect = 1e-81
Identities = 276/930 (29%), Positives = 422/930 (45%), Gaps = 176/930 (18%)
Query: 74 NPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGD 133
+PA + +G N +P ++ K+ +LV E +D+ + IL +AA+VS L+++
Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78
Query: 134 NALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQK 193
EE E T ++E I+L +V +V + + + E L+ + K
Sbjct: 79 ----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK 128
Query: 194 FTVIRGGQ--VIQIPVADITVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGESDH 249
VIR + V +I DI GDI +V GD +PAD LI+ L++D+S LTGES
Sbjct: 129 --VIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVS 186
Query: 250 VKK-----------SLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEE 298
V K + DK +L SGT++ G AVGV TG+ T LG
Sbjct: 187 VTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGL-HTELG------ 233
Query: 299 EKKDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKE 358
K + Q A+E E
Sbjct: 234 ----------KIRSQMAAVE--------------------------------------PE 245
Query: 359 KSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVK 418
++ LQ KL + Q+ A +S I V + V+ WL V
Sbjct: 246 RTPLQRKLDEFGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA--------VY 294
Query: 419 FFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTG 478
+F I V + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTG
Sbjct: 295 YFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTG 354
Query: 479 TLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGIS-------------VNCAY- 524
TLT N+M+V + ++ V E +A + + ++G + V C
Sbjct: 355 TLTTNQMSVCRMFV-------VAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQF 407
Query: 525 -------------TSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVR------- 564
L + G+ VG TE AL L+ + D++
Sbjct: 408 DGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVER 467
Query: 565 ----NEIPEEALYKVYT--FNSVRKSMSTVLK------NSDGSYRIFSKGASEIILKKCF 612
N + ++ + K +T F+ RKSMS GS ++F KGA E ++++C
Sbjct: 468 AGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGS-KMFVKGAPESVIERCS 526
Query: 613 KILSANGEAKVFRPRDRDDIVKTVIE-PMASEGLRTICLAFRDFPAGEPEPEWDNENDIV 671
+ + A + P R+ I+ + + S+ LR + LA RD P + + E D+ + V
Sbjct: 527 SVRVGSRTAPL-TPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFV 585
Query: 672 ---TGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPG 728
T LT + VG+ DP RPEV I +C +AGI V M+TGDN TA AI + GI
Sbjct: 586 QYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDT 645
Query: 729 EDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQ 788
ED + GK + R E ++ E+ + R AR P K +V+ +
Sbjct: 646 ED---VAGKAYTGR---EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSF 694
Query: 789 RQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNV 848
++ A+TGDG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +
Sbjct: 695 NEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAI 753
Query: 849 YDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPT 908
Y ++ +F+++ ++ NV V+ F A + L VQ+LWVNL+ D L + AL PP
Sbjct: 754 YSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPD 813
Query: 909 ESLLLRKPYGRNKPLISRTMMKNILGHAFY 938
++ + P + LIS + L Y
Sbjct: 814 LDIMEKLPRSPREALISGWLFFRYLAIGVY 843
>gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo
sapiens]
Length = 1052
Score = 302 bits (774), Expect = 1e-81
Identities = 276/930 (29%), Positives = 422/930 (45%), Gaps = 176/930 (18%)
Query: 74 NPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGD 133
+PA + +G N +P ++ K+ +LV E +D+ + IL +AA+VS L+++
Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78
Query: 134 NALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQK 193
EE E T ++E I+L +V +V + + + E L+ + K
Sbjct: 79 ----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK 128
Query: 194 FTVIRGGQ--VIQIPVADITVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGESDH 249
VIR + V +I DI GDI +V GD +PAD LI+ L++D+S LTGES
Sbjct: 129 --VIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVS 186
Query: 250 VKK-----------SLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEE 298
V K + DK +L SGT++ G AVGV TG+ T LG
Sbjct: 187 VTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGL-HTELG------ 233
Query: 299 EKKDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKE 358
K + Q A+E E
Sbjct: 234 ----------KIRSQMAAVE--------------------------------------PE 245
Query: 359 KSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVK 418
++ LQ KL + Q+ A +S I V + V+ WL V
Sbjct: 246 RTPLQRKLDEFGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA--------VY 294
Query: 419 FFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTG 478
+F I V + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTG
Sbjct: 295 YFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTG 354
Query: 479 TLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGIS-------------VNCAY- 524
TLT N+M+V + ++ V E +A + + ++G + V C
Sbjct: 355 TLTTNQMSVCRMFV-------VAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQF 407
Query: 525 -------------TSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVR------- 564
L + G+ VG TE AL L+ + D++
Sbjct: 408 DGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVER 467
Query: 565 ----NEIPEEALYKVYT--FNSVRKSMSTVLK------NSDGSYRIFSKGASEIILKKCF 612
N + ++ + K +T F+ RKSMS GS ++F KGA E ++++C
Sbjct: 468 AGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGS-KMFVKGAPESVIERCS 526
Query: 613 KILSANGEAKVFRPRDRDDIVKTVIE-PMASEGLRTICLAFRDFPAGEPEPEWDNENDIV 671
+ + A + P R+ I+ + + S+ LR + LA RD P + + E D+ + V
Sbjct: 527 SVRVGSRTAPL-TPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFV 585
Query: 672 ---TGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPG 728
T LT + VG+ DP RPEV I +C +AGI V M+TGDN TA AI + GI
Sbjct: 586 QYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDT 645
Query: 729 EDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQ 788
ED + GK + R E ++ E+ + R AR P K +V+ +
Sbjct: 646 ED---VAGKAYTGR---EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSF 694
Query: 789 RQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNV 848
++ A+TGDG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +
Sbjct: 695 NEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAI 753
Query: 849 YDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPT 908
Y ++ +F+++ ++ NV V+ F A + L VQ+LWVNL+ D L + AL PP
Sbjct: 754 YSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPD 813
Query: 909 ESLLLRKPYGRNKPLISRTMMKNILGHAFY 938
++ + P + LIS + L Y
Sbjct: 814 LDIMEKLPRSPREALISGWLFFRYLAIGVY 843
>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b
[Homo sapiens]
Length = 994
Score = 293 bits (749), Expect = 9e-79
Identities = 263/908 (28%), Positives = 408/908 (44%), Gaps = 160/908 (17%)
Query: 75 PADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGDN 134
P ++R +G N +P ++ KT +LV E +D+ + IL +AA +S L++++ EG+
Sbjct: 26 PDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFE--EGEE 83
Query: 135 ALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKF 194
+ T ++E ILL ++ +V + + + E L+ + K
Sbjct: 84 TI--------------TAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKV 129
Query: 195 TVIRGGQVIQIPVADITVGDIAQVKYGDLLPADG--ILIQGNDLKIDESSLTGESDHVKK 252
V +I DI GDI +V GD +PAD + I+ L++D+S LTGES V K
Sbjct: 130 YRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIK 189
Query: 253 -----------SLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKK 301
+ DK +L SGT++ G A+G+ + TG+
Sbjct: 190 HTEPVPDPRAVNQDKKNMLFSGTNIAAGK------ALGIVATTGV--------------- 228
Query: 302 DEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSV 361
+ G I ++ A QD K+
Sbjct: 229 ---------GTEIGKIRDQMAATEQD-------------------------------KTP 248
Query: 362 LQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFI 421
LQ KL + Q+ K L+ +I + +F V W + +F
Sbjct: 249 LQQKLDEFGEQLSKVISLICVAVWLINIGHFNDP---VHGGSWFRGA--------IYYFK 297
Query: 422 IGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLT 481
I V + V A+PEGLP +T LA ++M K N +VR L + ET+G + ICSDKTGTLT
Sbjct: 298 IAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLT 357
Query: 482 MNRMTVVQAYINEKHYKKV--------------PEPEAIP------PNILSYLVTGISVN 521
N+M+V + +I +K + PE E + P LV ++
Sbjct: 358 TNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATIC 417
Query: 522 CAYTSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVR-----------NEIPEE 570
L + G+ VG TE AL L+ + DVR N + +
Sbjct: 418 ALCNDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQ 477
Query: 571 ALYKVYT--FNSVRKSMSTVLKNSDGSY-----RIFSKGASEIILKKCFKILSANGEAKV 623
+ K +T F+ RKSMS + S ++F KGA E ++ +C + +
Sbjct: 478 LMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPL 537
Query: 624 FRPRDRDDIVKTVIE-PMASEGLRTICLAFRDFPAGEPEPEWDNENDIV---TGLTCIAV 679
P ++ I+ + E + LR + LA RD P E D+ + T LT + V
Sbjct: 538 TGPV-KEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGV 596
Query: 680 VGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFL--CLEGK 737
VG+ DP R EV +I+ C+ AGI V M+TGDN TA AI + GI E+ G+
Sbjct: 597 VGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGR 656
Query: 738 DFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGD 797
+F+ E+ E + AR P+ K +V+ + ++ A+TGD
Sbjct: 657 EFDDLPLAEQREACRRAC--------CFARVEPSHKSKIVEYL-----QSYDEITAMTGD 703
Query: 798 GTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQ 857
G ND PALKKA++G AMG +GT VAK AS+++L DDNF++IV AV GR +Y+++ +F++
Sbjct: 704 GVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIR 762
Query: 858 FQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPY 917
+ ++ NV V+ F A + L VQ+LWVNL+ D L + AL PP ++ R P
Sbjct: 763 YLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPR 822
Query: 918 GRNKPLIS 925
+PLIS
Sbjct: 823 SPKEPLIS 830
>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a
[Homo sapiens]
Length = 1001
Score = 293 bits (749), Expect = 9e-79
Identities = 263/908 (28%), Positives = 408/908 (44%), Gaps = 160/908 (17%)
Query: 75 PADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGDN 134
P ++R +G N +P ++ KT +LV E +D+ + IL +AA +S L++++ EG+
Sbjct: 26 PDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFE--EGEE 83
Query: 135 ALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKF 194
+ T ++E ILL ++ +V + + + E L+ + K
Sbjct: 84 TI--------------TAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKV 129
Query: 195 TVIRGGQVIQIPVADITVGDIAQVKYGDLLPADG--ILIQGNDLKIDESSLTGESDHVKK 252
V +I DI GDI +V GD +PAD + I+ L++D+S LTGES V K
Sbjct: 130 YRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIK 189
Query: 253 -----------SLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKK 301
+ DK +L SGT++ G A+G+ + TG+
Sbjct: 190 HTEPVPDPRAVNQDKKNMLFSGTNIAAGK------ALGIVATTGV--------------- 228
Query: 302 DEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSV 361
+ G I ++ A QD K+
Sbjct: 229 ---------GTEIGKIRDQMAATEQD-------------------------------KTP 248
Query: 362 LQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFI 421
LQ KL + Q+ K L+ +I + +F V W + +F
Sbjct: 249 LQQKLDEFGEQLSKVISLICVAVWLINIGHFNDP---VHGGSWFRGA--------IYYFK 297
Query: 422 IGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLT 481
I V + V A+PEGLP +T LA ++M K N +VR L + ET+G + ICSDKTGTLT
Sbjct: 298 IAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLT 357
Query: 482 MNRMTVVQAYINEKHYKKV--------------PEPEAIP------PNILSYLVTGISVN 521
N+M+V + +I +K + PE E + P LV ++
Sbjct: 358 TNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATIC 417
Query: 522 CAYTSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVR-----------NEIPEE 570
L + G+ VG TE AL L+ + DVR N + +
Sbjct: 418 ALCNDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQ 477
Query: 571 ALYKVYT--FNSVRKSMSTVLKNSDGSY-----RIFSKGASEIILKKCFKILSANGEAKV 623
+ K +T F+ RKSMS + S ++F KGA E ++ +C + +
Sbjct: 478 LMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPL 537
Query: 624 FRPRDRDDIVKTVIE-PMASEGLRTICLAFRDFPAGEPEPEWDNENDIV---TGLTCIAV 679
P ++ I+ + E + LR + LA RD P E D+ + T LT + V
Sbjct: 538 TGPV-KEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGV 596
Query: 680 VGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFL--CLEGK 737
VG+ DP R EV +I+ C+ AGI V M+TGDN TA AI + GI E+ G+
Sbjct: 597 VGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGR 656
Query: 738 DFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGD 797
+F+ E+ E + AR P+ K +V+ + ++ A+TGD
Sbjct: 657 EFDDLPLAEQREACRRAC--------CFARVEPSHKSKIVEYL-----QSYDEITAMTGD 703
Query: 798 GTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQ 857
G ND PALKKA++G AMG +GT VAK AS+++L DDNF++IV AV GR +Y+++ +F++
Sbjct: 704 GVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIR 762
Query: 858 FQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPY 917
+ ++ NV V+ F A + L VQ+LWVNL+ D L + AL PP ++ R P
Sbjct: 763 YLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPR 822
Query: 918 GRNKPLIS 925
+PLIS
Sbjct: 823 SPKEPLIS 830
>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
sapiens]
Length = 997
Score = 289 bits (740), Expect = 1e-77
Identities = 266/902 (29%), Positives = 410/902 (45%), Gaps = 135/902 (14%)
Query: 68 NEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFY 127
NE + +++ + +G N +P ++ KT L+LV E +D+ + IL +AA +S L+++
Sbjct: 19 NESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWF 78
Query: 128 QPPEGDNALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSR 187
+ EG+ + T ++E ILL +V +V + + + E L+
Sbjct: 79 E--EGEETI--------------TAFVEPFVILLILVANAIVGVWQERNAENAIEALKEY 122
Query: 188 IEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGIL--IQGNDLKIDESSLTG 245
+ K V +I DI GDI ++ GD +PAD L I+ L++D+S LTG
Sbjct: 123 EPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTG 182
Query: 246 ESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKK 305
ES V K D P R V
Sbjct: 183 ESVSVIKHTDPVP-----------DPRAV------------------------------N 201
Query: 306 KEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQGK 365
++KKN G G AM + G +D+ A ++E++ LQ K
Sbjct: 202 QDKKNMLFSGT-------NIAAGKAMGVVVATGVNTEIGKIRDEMVAT--EQERTPLQQK 252
Query: 366 LTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVT 425
L + Q+ K L+ II + +F V W I+ + +F I V
Sbjct: 253 LDEFGEQLSKVISLICIAVWIINIGHFNDP---VHGGSW--------IRGAIYYFKIAVA 301
Query: 426 VLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRM 485
+ V A+PEGLP +T LA ++M K N +VR L + ET+G + ICSDKTGTLT N+M
Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361
Query: 486 TVVQAYINEK----------------HYKKVPE--PEAIPPNILSY--LVTGISVNCAYT 525
+V + +I ++ Y + E + P N Y LV ++
Sbjct: 362 SVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCN 421
Query: 526 SKILPPEKEGGLPRHVGNKTECALLGLLLDL-----------KRDYQDVRNEIPEEALYK 574
L + G+ VG TE AL L+ + K + + N + ++ + K
Sbjct: 422 DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKK 481
Query: 575 VYT--FNSVRKSMSTVLKNSDGSY----RIFSKGASEIILKKCFKILSANGEAKVFRPRD 628
+T F+ RKSMS + S ++F KGA E ++ +C I G KV
Sbjct: 482 EFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRV--GSTKVPMTSG 539
Query: 629 RDDIVKTVIEPMAS--EGLRTICLAFRDFPAGEPEPEWDNENDIV---TGLTCIAVVGIE 683
+ +VI S + LR + LA D P E ++ + + T LT + VG+
Sbjct: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 599
Query: 684 DPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRI 743
DP R EV ++K C++AGI V M+TGDN TA AI + GI ED + K F R
Sbjct: 600 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDED---VTSKAFTGR- 655
Query: 744 RNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGDGTNDGP 803
E E+ R AR P+ K +V+ + ++ A+TGDG ND P
Sbjct: 656 --EFDELNPSAQRDACLNARCFARVEPSHKSKIVEFL-----QSFDEITAMTGDGVNDAP 708
Query: 804 ALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVN 863
ALKKA++G AMG +GT VAK AS+++L DDNF++IV AV GR +Y+++ +F+++ ++ N
Sbjct: 709 ALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSN 767
Query: 864 VVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPL 923
V V+ F A + L VQ+LWVNL+ D L + AL PP ++ + P +PL
Sbjct: 768 VGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPL 827
Query: 924 IS 925
IS
Sbjct: 828 IS 829
>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1
[Homo sapiens]
Length = 1042
Score = 289 bits (740), Expect = 1e-77
Identities = 266/902 (29%), Positives = 410/902 (45%), Gaps = 135/902 (14%)
Query: 68 NEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFY 127
NE + +++ + +G N +P ++ KT L+LV E +D+ + IL +AA +S L+++
Sbjct: 19 NESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWF 78
Query: 128 QPPEGDNALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSR 187
+ EG+ + T ++E ILL +V +V + + + E L+
Sbjct: 79 E--EGEETI--------------TAFVEPFVILLILVANAIVGVWQERNAENAIEALKEY 122
Query: 188 IEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGIL--IQGNDLKIDESSLTG 245
+ K V +I DI GDI ++ GD +PAD L I+ L++D+S LTG
Sbjct: 123 EPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTG 182
Query: 246 ESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKK 305
ES V K D P R V
Sbjct: 183 ESVSVIKHTDPVP-----------DPRAV------------------------------N 201
Query: 306 KEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQGK 365
++KKN G G AM + G +D+ A ++E++ LQ K
Sbjct: 202 QDKKNMLFSGT-------NIAAGKAMGVVVATGVNTEIGKIRDEMVAT--EQERTPLQQK 252
Query: 366 LTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVT 425
L + Q+ K L+ II + +F V W I+ + +F I V
Sbjct: 253 LDEFGEQLSKVISLICIAVWIINIGHFNDP---VHGGSW--------IRGAIYYFKIAVA 301
Query: 426 VLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRM 485
+ V A+PEGLP +T LA ++M K N +VR L + ET+G + ICSDKTGTLT N+M
Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361
Query: 486 TVVQAYINEK----------------HYKKVPE--PEAIPPNILSY--LVTGISVNCAYT 525
+V + +I ++ Y + E + P N Y LV ++
Sbjct: 362 SVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCN 421
Query: 526 SKILPPEKEGGLPRHVGNKTECALLGLLLDL-----------KRDYQDVRNEIPEEALYK 574
L + G+ VG TE AL L+ + K + + N + ++ + K
Sbjct: 422 DSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKK 481
Query: 575 VYT--FNSVRKSMSTVLKNSDGSY----RIFSKGASEIILKKCFKILSANGEAKVFRPRD 628
+T F+ RKSMS + S ++F KGA E ++ +C I G KV
Sbjct: 482 EFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRV--GSTKVPMTSG 539
Query: 629 RDDIVKTVIEPMAS--EGLRTICLAFRDFPAGEPEPEWDNENDIV---TGLTCIAVVGIE 683
+ +VI S + LR + LA D P E ++ + + T LT + VG+
Sbjct: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 599
Query: 684 DPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRI 743
DP R EV ++K C++AGI V M+TGDN TA AI + GI ED + K F R
Sbjct: 600 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDED---VTSKAFTGR- 655
Query: 744 RNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGDGTNDGP 803
E E+ R AR P+ K +V+ + ++ A+TGDG ND P
Sbjct: 656 --EFDELNPSAQRDACLNARCFARVEPSHKSKIVEFL-----QSFDEITAMTGDGVNDAP 708
Query: 804 ALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVN 863
ALKKA++G AMG +GT VAK AS+++L DDNF++IV AV GR +Y+++ +F+++ ++ N
Sbjct: 709 ALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSN 767
Query: 864 VVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPL 923
V V+ F A + L VQ+LWVNL+ D L + AL PP ++ + P +PL
Sbjct: 768 VGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPL 827
Query: 924 IS 925
IS
Sbjct: 828 IS 829
>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sapiens]
Length = 939
Score = 268 bits (684), Expect = 3e-71
Identities = 199/674 (29%), Positives = 338/674 (50%), Gaps = 78/674 (11%)
Query: 417 VKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDK 476
++ F I V++ V A+PEGLP+ VT++LA V +M+K +V+ L ET+G ICSDK
Sbjct: 292 LEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDK 351
Query: 477 TGTLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGG 536
TGTLT N MTV + ++ + +V + N ++ V + + + E G
Sbjct: 352 TGTLTKNEMTVTHIFTSDGLHAEVT---GVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAG 408
Query: 537 LPRH---------VGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKV-YTFNSVRKSMS 586
+ +G TE AL+ L + + D + ++ + K Y F+S +K M+
Sbjct: 409 CVCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQDYIRKAEYPFSSEQKWMA 462
Query: 587 TVLKNSDGSYR---IFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASE 643
+ R F KGA E ++K C S G+ + RD + + M S
Sbjct: 463 VKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQS-KGQTLTLTQQQRD-VYQQEKARMGSA 520
Query: 644 GLRTICLAFRDFPAGEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGIT 703
GLR + LA PE + LT + +VGI DP R V +A+ +G++
Sbjct: 521 GLRVLALA------SGPE---------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVS 565
Query: 704 VRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIRNEKGE----IEQERIDKIW 759
++M+TGD+ TA AIA++ G+ +++ ++ GE ++ +++ +I
Sbjct: 566 IKMITGDSQETAVAIASRLGL--------------YSKTSQSVSGEEIDAMDVQQLSQIV 611
Query: 760 PKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGT 819
PK+ V R+SP K ++K + VVA+TGDG ND ALK AD+G AMG GT
Sbjct: 612 PKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGT 666
Query: 820 DVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQD 879
DV KEA+D+IL DD+F +I+ A+ G+ +Y++I F++FQL+ ++ A+ + +
Sbjct: 667 DVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFP 726
Query: 880 SPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQ 939
+PL A+Q+LW+N+IMD + +L EP + ++ + P ++++ ++ IL +
Sbjct: 727 NPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI-- 784
Query: 940 LVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNV 999
++V TL + D + T+ F FV +FN +++R ++V
Sbjct: 785 IIVCGTLFVFWRELRD---------NVITPRDTTMTFTCFVFFDMFNALSSRS--QTKSV 833
Query: 1000 FE-GIFNNAIFCTIVLGTFVVQIIIVQFG--GKPFSCSELSIEQWLWSIFLGMGTLLWGQ 1056
FE G+ +N +FC VLG+ + Q++++ F K F LSI L+ + L + +
Sbjct: 834 FEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAE 893
Query: 1057 LISTIPTSRLKFLK 1070
+I + SR K K
Sbjct: 894 IIKKVERSREKIQK 907
Score = 61.6 bits (148), Expect = 4e-09
Identities = 48/163 (29%), Positives = 72/163 (44%), Gaps = 16/163 (9%)
Query: 155 EGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGD 214
+ +I ++++ VV V ++ EK L + E +R G++ D+ GD
Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159
Query: 215 IAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDP------------LLLS 262
+ GD +PAD L + DL IDESSLTGE+ K P +
Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219
Query: 263 GTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKK 305
GT V G + VV G NS+ G +F ++ A EE K +K
Sbjct: 220 GTLVRCGKAKGVVIGTGENSEFGEVFKMMQA--EEAPKTPLQK 260
>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sapiens]
Length = 949
Score = 268 bits (684), Expect = 3e-71
Identities = 199/674 (29%), Positives = 338/674 (50%), Gaps = 78/674 (11%)
Query: 417 VKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDK 476
++ F I V++ V A+PEGLP+ VT++LA V +M+K +V+ L ET+G ICSDK
Sbjct: 292 LEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDK 351
Query: 477 TGTLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGG 536
TGTLT N MTV + ++ + +V + N ++ V + + + E G
Sbjct: 352 TGTLTKNEMTVTHIFTSDGLHAEVT---GVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAG 408
Query: 537 LPRH---------VGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKV-YTFNSVRKSMS 586
+ +G TE AL+ L + + D + ++ + K Y F+S +K M+
Sbjct: 409 CVCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQDYIRKAEYPFSSEQKWMA 462
Query: 587 TVLKNSDGSYR---IFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASE 643
+ R F KGA E ++K C S G+ + RD + + M S
Sbjct: 463 VKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQS-KGQTLTLTQQQRD-VYQQEKARMGSA 520
Query: 644 GLRTICLAFRDFPAGEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGIT 703
GLR + LA PE + LT + +VGI DP R V +A+ +G++
Sbjct: 521 GLRVLALA------SGPE---------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVS 565
Query: 704 VRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIRNEKGE----IEQERIDKIW 759
++M+TGD+ TA AIA++ G+ +++ ++ GE ++ +++ +I
Sbjct: 566 IKMITGDSQETAVAIASRLGL--------------YSKTSQSVSGEEIDAMDVQQLSQIV 611
Query: 760 PKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGT 819
PK+ V R+SP K ++K + VVA+TGDG ND ALK AD+G AMG GT
Sbjct: 612 PKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGT 666
Query: 820 DVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQD 879
DV KEA+D+IL DD+F +I+ A+ G+ +Y++I F++FQL+ ++ A+ + +
Sbjct: 667 DVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFP 726
Query: 880 SPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQ 939
+PL A+Q+LW+N+IMD + +L EP + ++ + P ++++ ++ IL +
Sbjct: 727 NPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI-- 784
Query: 940 LVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNV 999
++V TL + D + T+ F FV +FN +++R ++V
Sbjct: 785 IIVCGTLFVFWRELRD---------NVITPRDTTMTFTCFVFFDMFNALSSRS--QTKSV 833
Query: 1000 FE-GIFNNAIFCTIVLGTFVVQIIIVQFG--GKPFSCSELSIEQWLWSIFLGMGTLLWGQ 1056
FE G+ +N +FC VLG+ + Q++++ F K F LSI L+ + L + +
Sbjct: 834 FEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAE 893
Query: 1057 LISTIPTSRLKFLK 1070
+I + SR K K
Sbjct: 894 IIKKVERSREKIQK 907
Score = 61.6 bits (148), Expect = 4e-09
Identities = 48/163 (29%), Positives = 72/163 (44%), Gaps = 16/163 (9%)
Query: 155 EGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGD 214
+ +I ++++ VV V ++ EK L + E +R G++ D+ GD
Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159
Query: 215 IAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDP------------LLLS 262
+ GD +PAD L + DL IDESSLTGE+ K P +
Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219
Query: 263 GTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKK 305
GT V G + VV G NS+ G +F ++ A EE K +K
Sbjct: 220 GTLVRCGKAKGVVIGTGENSEFGEVFKMMQA--EEAPKTPLQK 260
>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sapiens]
Length = 919
Score = 268 bits (684), Expect = 3e-71
Identities = 199/674 (29%), Positives = 338/674 (50%), Gaps = 78/674 (11%)
Query: 417 VKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDK 476
++ F I V++ V A+PEGLP+ VT++LA V +M+K +V+ L ET+G ICSDK
Sbjct: 292 LEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDK 351
Query: 477 TGTLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGG 536
TGTLT N MTV + ++ + +V + N ++ V + + + E G
Sbjct: 352 TGTLTKNEMTVTHIFTSDGLHAEVT---GVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAG 408
Query: 537 LPRH---------VGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKV-YTFNSVRKSMS 586
+ +G TE AL+ L + + D + ++ + K Y F+S +K M+
Sbjct: 409 CVCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQDYIRKAEYPFSSEQKWMA 462
Query: 587 TVLKNSDGSYR---IFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASE 643
+ R F KGA E ++K C S G+ + RD + + M S
Sbjct: 463 VKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQS-KGQTLTLTQQQRD-VYQQEKARMGSA 520
Query: 644 GLRTICLAFRDFPAGEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGIT 703
GLR + LA PE + LT + +VGI DP R V +A+ +G++
Sbjct: 521 GLRVLALA------SGPE---------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVS 565
Query: 704 VRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIRNEKGE----IEQERIDKIW 759
++M+TGD+ TA AIA++ G+ +++ ++ GE ++ +++ +I
Sbjct: 566 IKMITGDSQETAVAIASRLGL--------------YSKTSQSVSGEEIDAMDVQQLSQIV 611
Query: 760 PKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGT 819
PK+ V R+SP K ++K + VVA+TGDG ND ALK AD+G AMG GT
Sbjct: 612 PKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGT 666
Query: 820 DVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQD 879
DV KEA+D+IL DD+F +I+ A+ G+ +Y++I F++FQL+ ++ A+ + +
Sbjct: 667 DVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFP 726
Query: 880 SPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQ 939
+PL A+Q+LW+N+IMD + +L EP + ++ + P ++++ ++ IL +
Sbjct: 727 NPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI-- 784
Query: 940 LVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNV 999
++V TL + D + T+ F FV +FN +++R ++V
Sbjct: 785 IIVCGTLFVFWRELRD---------NVITPRDTTMTFTCFVFFDMFNALSSRS--QTKSV 833
Query: 1000 FE-GIFNNAIFCTIVLGTFVVQIIIVQFG--GKPFSCSELSIEQWLWSIFLGMGTLLWGQ 1056
FE G+ +N +FC VLG+ + Q++++ F K F LSI L+ + L + +
Sbjct: 834 FEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAE 893
Query: 1057 LISTIPTSRLKFLK 1070
+I + SR K K
Sbjct: 894 IIKKVERSREKIQK 907
Score = 61.6 bits (148), Expect = 4e-09
Identities = 48/163 (29%), Positives = 72/163 (44%), Gaps = 16/163 (9%)
Query: 155 EGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGD 214
+ +I ++++ VV V ++ EK L + E +R G++ D+ GD
Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159
Query: 215 IAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDP------------LLLS 262
+ GD +PAD L + DL IDESSLTGE+ K P +
Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219
Query: 263 GTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKK 305
GT V G + VV G NS+ G +F ++ A EE K +K
Sbjct: 220 GTLVRCGKAKGVVIGTGENSEFGEVFKMMQA--EEAPKTPLQK 260
>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sapiens]
Length = 888
Score = 261 bits (667), Expect = 3e-69
Identities = 194/651 (29%), Positives = 328/651 (50%), Gaps = 84/651 (12%)
Query: 417 VKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDK 476
++ F I V++ V A+PEGLP+ VT++LA V +M+K +V+ L ET+G ICSDK
Sbjct: 292 LEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDK 351
Query: 477 TGTLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGG 536
TGTLT N MTV + ++ + +V + N ++ V + + + E G
Sbjct: 352 TGTLTKNEMTVTHIFTSDGLHAEVT---GVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAG 408
Query: 537 LPRH---------VGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKV-YTFNSVRKSMS 586
+ +G TE AL+ L + + D + ++ + K Y F+S +K M+
Sbjct: 409 CVCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQDYIRKAEYPFSSEQKWMA 462
Query: 587 TVLKNSDGSYR---IFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASE 643
+ R F KGA E ++K C S G+ + RD + + M S
Sbjct: 463 VKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQS-KGQTLTLTQQQRD-VYQQEKARMGSA 520
Query: 644 GLRTICLAFRDFPAGEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGIT 703
GLR + LA PE + LT + +VGI DP R V +A+ +G++
Sbjct: 521 GLRVLALA------SGPE---------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVS 565
Query: 704 VRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIRNEKGE----IEQERIDKIW 759
++M+TGD+ TA AIA++ G+ +++ ++ GE ++ +++ +I
Sbjct: 566 IKMITGDSQETAVAIASRLGL--------------YSKTSQSVSGEEIDAMDVQQLSQIV 611
Query: 760 PKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGT 819
PK+ V R+SP K ++K + VVA+TGDG ND ALK AD+G AMG GT
Sbjct: 612 PKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGT 666
Query: 820 DVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQD 879
DV KEA+D+IL DD+F +I+ A+ G+ +Y++I F++FQL+ ++ A+ + +
Sbjct: 667 DVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFP 726
Query: 880 SPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQ 939
+PL A+Q+LW+N+IMD + +L EP + ++ + P ++++ ++ IL +
Sbjct: 727 NPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI-- 784
Query: 940 LVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNV 999
++V TL + D + T+ F FV +FN +++R ++V
Sbjct: 785 IIVCGTLFVFWRELRD---------NVITPRDTTMTFTCFVFFDMFNALSSRS--QTKSV 833
Query: 1000 FE-GIFNNAIFCTIVLGTFVVQIIIVQFG--GKPFSCSELSI------EQW 1041
FE G+ +N +FC VLG+ + Q++++ F K F LSI E+W
Sbjct: 834 FEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILGLALGEEW 884
Score = 61.6 bits (148), Expect = 4e-09
Identities = 48/163 (29%), Positives = 72/163 (44%), Gaps = 16/163 (9%)
Query: 155 EGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGD 214
+ +I ++++ VV V ++ EK L + E +R G++ D+ GD
Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159
Query: 215 IAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDP------------LLLS 262
+ GD +PAD L + DL IDESSLTGE+ K P +
Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219
Query: 263 GTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKK 305
GT V G + VV G NS+ G +F ++ A EE K +K
Sbjct: 220 GTLVRCGKAKGVVIGTGENSEFGEVFKMMQA--EEAPKTPLQK 260
>gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3
[Homo sapiens]
Length = 1015
Score = 256 bits (655), Expect = 7e-68
Identities = 253/900 (28%), Positives = 399/900 (44%), Gaps = 158/900 (17%)
Query: 68 NEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFY 127
NE + +++ + +G N +P ++ KT L+LV E +D+ + IL +AA +S L+++
Sbjct: 19 NESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWF 78
Query: 128 QPPEGDNALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSR 187
+ EG+ + T ++E ILL +V +V + + R ++
Sbjct: 79 E--EGEETI--------------TAFVEPFVILLILVANAIVGVWQE-------RNAENA 115
Query: 188 IEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGES 247
IE +++ G Q + + ++K D++P D + + GES
Sbjct: 116 IEALKEYEPEMGKVYRQDRKS------VQRIKAKDIVPGDIV------------EIAGES 157
Query: 248 DHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKKKE 307
V K D P R V ++
Sbjct: 158 VSVIKHTDPVP-----------DPRAV------------------------------NQD 176
Query: 308 KKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQGKLT 367
KKN G G AM + G +D+ A ++E++ LQ KL
Sbjct: 177 KKNMLFSGT-------NIAAGKAMGVVVATGVNTEIGKIRDEMVAT--EQERTPLQQKLD 227
Query: 368 KLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVL 427
+ Q+ K L+ II + +F V W I+ + +F I V +
Sbjct: 228 EFGEQLSKVISLICIAVWIINIGHFNDP---VHGGSW--------IRGAIYYFKIAVALA 276
Query: 428 VVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTV 487
V A+PEGLP +T LA ++M K N +VR L + ET+G + ICSDKTGTLT N+M+V
Sbjct: 277 VAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSV 336
Query: 488 VQAYINEK----------------HYKKVPE--PEAIPPNILSY--LVTGISVNCAYTSK 527
+ +I ++ Y + E + P N Y LV ++
Sbjct: 337 CRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDS 396
Query: 528 ILPPEKEGGLPRHVGNKTECALLGLLLDL-----------KRDYQDVRNEIPEEALYKVY 576
L + G+ VG TE AL L+ + K + + N + ++ + K +
Sbjct: 397 ALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEF 456
Query: 577 T--FNSVRKSMSTVLKNSDGSY----RIFSKGASEIILKKCFKILSANGEAKVFRPRDRD 630
T F+ RKSMS + S ++F KGA E ++ +C I G KV
Sbjct: 457 TLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRV--GSTKVPMTSGVK 514
Query: 631 DIVKTVIEPMAS--EGLRTICLAFRDFPAGEPEPEWDNENDIV---TGLTCIAVVGIEDP 685
+ +VI S + LR + LA D P E ++ + + T LT + VG+ DP
Sbjct: 515 QKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDP 574
Query: 686 VRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIRN 745
R EV ++K C++AGI V M+TGDN TA AI + GI ED + K F R
Sbjct: 575 PRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDED---VTSKAFTGR--- 628
Query: 746 EKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGDGTNDGPAL 805
E E+ R AR P+ K +V+ + ++ A+TGDG ND PAL
Sbjct: 629 EFDELNPSAQRDACLNARCFARVEPSHKSKIVEFL-----QSFDEITAMTGDGVNDAPAL 683
Query: 806 KKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVV 865
KKA++G AMG +GT VAK AS+++L DDNF++IV AV GR +Y+++ +F+++ ++ NV
Sbjct: 684 KKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVG 742
Query: 866 AVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLIS 925
V+ F A + L VQ+LWVNL+ D L + AL PP ++ + P +PLIS
Sbjct: 743 EVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLIS 802
>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
Length = 1039
Score = 249 bits (635), Expect = 1e-65
Identities = 224/755 (29%), Positives = 353/755 (46%), Gaps = 103/755 (13%)
Query: 367 TKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTV 426
T +A++I +++ + V I +L+F+I + ++Y V II +
Sbjct: 297 TPIAIEIEHFVHIVAGVAVSIGILFFII---------------AVSLKYQVLDSIIFLIG 341
Query: 427 LVVA-VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRM 485
++VA VPEGL VT++L+ + K+M K N LV++L+A ET+G+ + ICSDKTGTLT NRM
Sbjct: 342 IIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRM 401
Query: 486 TVVQAYIN---------EKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGG 536
TV + + E H +V + + LS ++T ++ P ++
Sbjct: 402 TVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIIT-----LCNRAEFKPGQENVP 456
Query: 537 LPRH--VGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDG 594
+ + +G+ +E ALL + D ++R + A FNS K ++ + D
Sbjct: 457 IMKKAVIGDASETALLKFSEVILGDVMEIRKRNRKVA---EIPFNSTNKFQLSIHEMDDP 513
Query: 595 SYRIF---SKGASEIILKKCFKILSANGEAKVFRPRDRDDI--VKTVIEPMASEGLRTIC 649
+ F KGA E IL+KC I+ NGE P D+ T + G R +
Sbjct: 514 HGKRFLMVMKGAPERILEKCSTIM-INGEE---HPLDKSTAKTFHTAYMELGGLGERVLG 569
Query: 650 LAFRDFPAGE-PEP---EWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVR 705
PA E PE + D N + L + ++ + DP R VPDA+ KC+ AGI V
Sbjct: 570 FCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVI 629
Query: 706 MVTGDNINTARAIATKCGILHPGEDF-------LCLEGKDFNRRIRN-------EKGEIE 751
MVTGD+ TA+AIA GI+ + L + + N+R E ++
Sbjct: 630 MVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMS 689
Query: 752 QERIDKIWPKLR--VLARSSPTDKHTLVKGIIDSTVSDQRQ--VVAVTGDGTNDGPALKK 807
E++D+I + V AR+SP K +V+G QRQ VVAVTGDG ND PALKK
Sbjct: 690 SEQLDEILANYQEIVFARTSPQQKLIIVEGC-------QRQDAVVAVTGDGVNDSPALKK 742
Query: 808 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 867
AD+G AMGIAG+D AK A+D++L DDNF SIV V GR ++D++ K + + LT N+ +
Sbjct: 743 ADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAEL 802
Query: 868 IVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNK------ 921
+ P+ + +L+++L D + S+ALA E ++ RKP +NK
Sbjct: 803 CPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQ 862
Query: 922 PLISRTMMKNILGHAFYQLVVVFTLLFAGEKFF-----------------DIDSGRNAPL 964
PL + + L A +V FT ++A E F D+
Sbjct: 863 PLAVYSYLHIGLMQALGAFLVYFT-VYAQEGFLPRTLINLRVEWEKDYVNDLKDSYGQEW 921
Query: 965 HAPPSEH-----YTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVV 1019
E+ YT F +L+Q ++ RK +G+F N + + ++
Sbjct: 922 TRYQREYLEWTGYTAFF-VGILVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGITSQIII 980
Query: 1020 QIIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLW 1054
+I+ G + S + W + + L+W
Sbjct: 981 GLILSYGLGSVTALSFTMLRAQYWFVAVPHAILIW 1015
Score = 58.2 bits (139), Expect = 5e-08
Identities = 75/313 (23%), Positives = 130/313 (41%), Gaps = 56/313 (17%)
Query: 3 DMANNSVAYSGVKNS---LKEANHDGDFGITLAELRALMELRSTD---ALRKIQESYGDV 56
D + Y G+KN+ LK+ NH +F EL D + R+++E YG
Sbjct: 23 DKGDGKEKYRGLKNNCLELKKKNHKEEFQ---------KELHLDDHKLSNRELEEKYG-- 71
Query: 57 YGICTKLKTSPNEGLSGN-PADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILE 115
T GLS A+L R+ + PPK+ ++ + + + + I+L
Sbjct: 72 --------TDIIMGLSSTRAAELLARDGP--NSLTPPKQTPEIVKFLKQMVGGFS-ILLW 120
Query: 116 IAAIVSLGLSFYQPPEGDNALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDW 175
+ A LC ++ G + ++ + + + VV++T +
Sbjct: 121 VGAF----------------LCW-IAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAY 163
Query: 176 SKEKQFRGLQSRIEQ--EQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQG 233
+E + + S + Q+ VIR + IP + VGDI +VK GD +PAD ++
Sbjct: 164 YQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSS 223
Query: 234 NDLKIDESSLTGESDHVKKS--------LDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTG 285
++D SSLTGES+ +S L+ + T +EG+ +V G + G
Sbjct: 224 QGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIG 283
Query: 286 IIFTLLGAGGEEE 298
I +L G E+
Sbjct: 284 HIASLASGVGNEK 296
>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
sapiens]
Length = 946
Score = 248 bits (632), Expect = 3e-65
Identities = 194/625 (31%), Positives = 304/625 (48%), Gaps = 72/625 (11%)
Query: 417 VKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDK 476
+ F IGV++ V A+PEGLP+ V ++L V +M K +V+ L ET+G + +CSDK
Sbjct: 321 LSMFTIGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCSVLCSDK 380
Query: 477 TGTLTMNRMTVVQAYINEKHYKKV--------------PEPEAIPPNILSYLVTGISVNC 522
TGTLT N MTV Q ++ +V P E I + + C
Sbjct: 381 TGTLTANEMTVTQLVTSDGLRAEVSGVGYDGQGTVCLLPSKEVIKEFSNVSVGKLVEAGC 440
Query: 523 AYTSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVR 582
+ ++ G P TE AL+ L + K D D++N + K F+S +
Sbjct: 441 VANNAVIRKNAVMGQP------TEGALMALAM--KMDLSDIKNSYIRK---KEIPFSSEQ 489
Query: 583 KSMSTV--LKNSDGSYRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPM 640
K M+ LK D F KGA E +++ C + + G P+ R ++ + M
Sbjct: 490 KWMAVKCSLKTEDQEDIYFMKGALEEVIRYC-TMYNNGGIPLPLTPQQRSFCLQEE-KRM 547
Query: 641 ASEGLRTICLAFRDFPAGEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRA 700
S GLR + LA PE + LT + +VGI DP R V +A++ +
Sbjct: 548 GSLGLRVLALA------SGPE---------LGRLTFLGLVGIIDPPRVGVKEAVQVLSES 592
Query: 701 GITVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWP 760
G++V+M+TGD + TA AI G+ + + E D EKGE+ +R+ K+
Sbjct: 593 GVSVKMITGDALETALAIGRNIGLCNGKLQAMSGEEVD-----SVEKGELA-DRVGKV-- 644
Query: 761 KLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTD 820
V R+SP K ++K + +S +VA+TGDG ND ALK AD+G AMG GTD
Sbjct: 645 --SVFFRTSPKHKLKIIKALQESGA-----IVAMTGDGVNDAVALKSADIGIAMGQTGTD 697
Query: 821 VAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDS 880
V+KEA+++IL DD+F++I+ AV G+ ++ +I F++FQL+ ++ A+ + S
Sbjct: 698 VSKEAANMILVDDDFSAIMNAVEEGKGIFYNIKNFVRFQLSTSISALSLITLSTVFNLPS 757
Query: 881 PLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQL 940
PL A+Q+LW+N+IMD + +L EP + + P ++SR ++ IL A
Sbjct: 758 PLNAMQILWINIIMDGPPAQSLGVEPVDKDAFRQPPRSVRDTILSRALILKILMSA---A 814
Query: 941 VVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNVF 1000
+++ LF K D A T+ F FV LFN + R + +F
Sbjct: 815 IIISGTLFIFWKEMPED-------RASTPRTTTMTFTCFVFFDLFNALTCRS--QTKLIF 865
Query: 1001 E-GIFNNAIFCTIVLGTFVVQIIIV 1024
E G N +F VLG+ + Q+ ++
Sbjct: 866 EIGFLRNHMFLYSVLGSILGQLAVI 890
Score = 65.5 bits (158), Expect = 3e-10
Identities = 48/169 (28%), Positives = 78/169 (46%), Gaps = 14/169 (8%)
Query: 155 EGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGD 214
+ +I +V+ VV V ++ EK L + E +R G++ + ++ GD
Sbjct: 133 DAVSIATAVLVVVTVAFIQEYRSEKSLEELTKMVPPE--CNCLREGKLQHLLARELVPGD 190
Query: 215 IAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKS----------LDKDPLLLSGT 264
+ + GD +PAD L + DL +DESS TGE++ K+ ++ GT
Sbjct: 191 VVSLSIGDRIPADIRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGGDLTTLSNIVFMGT 250
Query: 265 HVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKKKEKKNKKQ 313
V G G+ VV G +SQ G +F ++ A EE K +K + KQ
Sbjct: 251 LVQYGRGQGVVIGTGESSQFGEVFKMMQA--EETPKTPLQKSMDRLGKQ 297
>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo
sapiens]
Length = 1023
Score = 236 bits (602), Expect = 1e-61
Identities = 197/632 (31%), Positives = 313/632 (49%), Gaps = 88/632 (13%)
Query: 360 SVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKF 419
S L+G T +A +I +++ + V + V +F++ + + WL
Sbjct: 275 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL--ILEYTWLEAV----------I 322
Query: 420 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 479
F+IG+ +V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGT
Sbjct: 323 FLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 380
Query: 480 LTMNRMTVVQAYI-NEKHYKKVPEPEA-IPPNILSYLVTGISVNCAYTSKILPPEKEGGL 537
LT NRMTV + N+ H E ++ + + S +S ++ + + L
Sbjct: 381 LTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENL 440
Query: 538 P----RHVGNKTECALL-------GLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMS 586
P G+ +E ALL G + +++ Y + EIP FNS K
Sbjct: 441 PILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIV-EIP---------FNSTNKYQL 490
Query: 587 TVLKN---SDGSYRIFSKGASEIILKKCFKILSANGEAKVFRPRDRD--DIVKTVIEPMA 641
++ KN S+ + + KGA E IL +C IL E +P D + D + +
Sbjct: 491 SIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKE----QPLDEELKDAFQNAYLELG 546
Query: 642 SEGLRTI--CLAF---RDFPAGEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKK 696
G R + C F FP G + + D+ N + L + ++ + DP R VPDA+ K
Sbjct: 547 GLGERVLGFCHLFLPDEQFPEGF-QFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGK 605
Query: 697 CQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIR------------ 744
C+ AGI V MVTGD+ TA+AIA GI+ G + + +D R+
Sbjct: 606 CRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV----EDIAARLNIPVSQVNPRDAK 661
Query: 745 ------NEKGEIEQERIDKI--WPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQ--VVAV 794
++ ++ E++D I + V AR+SP K +V+G QRQ +VAV
Sbjct: 662 ACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGC-------QRQGAIVAV 714
Query: 795 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK 854
TGDG ND PALKKAD+G AMGIAG+DV+K+A+D+IL DDNF SIV V GR ++D++ K
Sbjct: 715 TGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKK 774
Query: 855 FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLR 914
+ + LT N+ + PL V +L ++L D + +++LA E ++ R
Sbjct: 775 SIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKR 834
Query: 915 KPYGRNKPLISRTMMKNILGHAFYQLVVVFTL 946
+P P + + + ++ A+ Q+ ++ L
Sbjct: 835 QP---RNPKTDKLVNERLISMAYGQIGMIQAL 863
Score = 70.1 bits (170), Expect = 1e-11
Identities = 51/156 (32%), Positives = 85/156 (54%), Gaps = 13/156 (8%)
Query: 144 EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVIRGGQV 202
EEE + + ++ ++LS V V++ F+ + + K + ++S + Q+ VIR G+
Sbjct: 122 EEEPQNDNLYL---GVVLSAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEK 177
Query: 203 IQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLD---KDPL 259
+ I ++ VGD+ +VK GD +PAD +I N K+D SSLTGES+ +S D ++PL
Sbjct: 178 MSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPL 237
Query: 260 -----LLSGTHVMEGSGRMVVTAVGVNSQTGIIFTL 290
T+ +EG+ R +V G + G I TL
Sbjct: 238 ETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATL 273
>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo
sapiens]
Length = 992
Score = 236 bits (602), Expect = 1e-61
Identities = 197/632 (31%), Positives = 313/632 (49%), Gaps = 88/632 (13%)
Query: 360 SVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKF 419
S L+G T +A +I +++ + V + V +F++ + + WL
Sbjct: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL--ILEYTWLEAV----------I 291
Query: 420 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 479
F+IG+ +V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGT
Sbjct: 292 FLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 349
Query: 480 LTMNRMTVVQAYI-NEKHYKKVPEPEA-IPPNILSYLVTGISVNCAYTSKILPPEKEGGL 537
LT NRMTV + N+ H E ++ + + S +S ++ + + L
Sbjct: 350 LTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENL 409
Query: 538 P----RHVGNKTECALL-------GLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMS 586
P G+ +E ALL G + +++ Y + EIP FNS K
Sbjct: 410 PILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIV-EIP---------FNSTNKYQL 459
Query: 587 TVLKN---SDGSYRIFSKGASEIILKKCFKILSANGEAKVFRPRDRD--DIVKTVIEPMA 641
++ KN S+ + + KGA E IL +C IL E +P D + D + +
Sbjct: 460 SIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKE----QPLDEELKDAFQNAYLELG 515
Query: 642 SEGLRTI--CLAF---RDFPAGEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKK 696
G R + C F FP G + + D+ N + L + ++ + DP R VPDA+ K
Sbjct: 516 GLGERVLGFCHLFLPDEQFPEGF-QFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGK 574
Query: 697 CQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIR------------ 744
C+ AGI V MVTGD+ TA+AIA GI+ G + + +D R+
Sbjct: 575 CRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV----EDIAARLNIPVSQVNPRDAK 630
Query: 745 ------NEKGEIEQERIDKI--WPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQ--VVAV 794
++ ++ E++D I + V AR+SP K +V+G QRQ +VAV
Sbjct: 631 ACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGC-------QRQGAIVAV 683
Query: 795 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK 854
TGDG ND PALKKAD+G AMGIAG+DV+K+A+D+IL DDNF SIV V GR ++D++ K
Sbjct: 684 TGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKK 743
Query: 855 FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLR 914
+ + LT N+ + PL V +L ++L D + +++LA E ++ R
Sbjct: 744 SIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKR 803
Query: 915 KPYGRNKPLISRTMMKNILGHAFYQLVVVFTL 946
+P P + + + ++ A+ Q+ ++ L
Sbjct: 804 QP---RNPKTDKLVNERLISMAYGQIGMIQAL 832
Score = 70.1 bits (170), Expect = 1e-11
Identities = 51/156 (32%), Positives = 85/156 (54%), Gaps = 13/156 (8%)
Query: 144 EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVIRGGQV 202
EEE + + ++ ++LS V V++ F+ + + K + ++S + Q+ VIR G+
Sbjct: 91 EEEPQNDNLYL---GVVLSAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEK 146
Query: 203 IQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLD---KDPL 259
+ I ++ VGD+ +VK GD +PAD +I N K+D SSLTGES+ +S D ++PL
Sbjct: 147 MSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPL 206
Query: 260 -----LLSGTHVMEGSGRMVVTAVGVNSQTGIIFTL 290
T+ +EG+ R +V G + G I TL
Sbjct: 207 ETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATL 242
>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
Length = 1023
Score = 236 bits (602), Expect = 1e-61
Identities = 197/632 (31%), Positives = 313/632 (49%), Gaps = 88/632 (13%)
Query: 360 SVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKF 419
S L+G T +A +I +++ + V + V +F++ + + WL
Sbjct: 275 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL--ILEYTWLEAV----------I 322
Query: 420 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 479
F+IG+ +V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGT
Sbjct: 323 FLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 380
Query: 480 LTMNRMTVVQAYI-NEKHYKKVPEPEA-IPPNILSYLVTGISVNCAYTSKILPPEKEGGL 537
LT NRMTV + N+ H E ++ + + S +S ++ + + L
Sbjct: 381 LTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENL 440
Query: 538 P----RHVGNKTECALL-------GLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMS 586
P G+ +E ALL G + +++ Y + EIP FNS K
Sbjct: 441 PILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIV-EIP---------FNSTNKYQL 490
Query: 587 TVLKN---SDGSYRIFSKGASEIILKKCFKILSANGEAKVFRPRDRD--DIVKTVIEPMA 641
++ KN S+ + + KGA E IL +C IL E +P D + D + +
Sbjct: 491 SIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKE----QPLDEELKDAFQNAYLELG 546
Query: 642 SEGLRTI--CLAF---RDFPAGEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKK 696
G R + C F FP G + + D+ N + L + ++ + DP R VPDA+ K
Sbjct: 547 GLGERVLGFCHLFLPDEQFPEGF-QFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGK 605
Query: 697 CQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIR------------ 744
C+ AGI V MVTGD+ TA+AIA GI+ G + + +D R+
Sbjct: 606 CRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV----EDIAARLNIPVSQVNPRDAK 661
Query: 745 ------NEKGEIEQERIDKI--WPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQ--VVAV 794
++ ++ E++D I + V AR+SP K +V+G QRQ +VAV
Sbjct: 662 ACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGC-------QRQGAIVAV 714
Query: 795 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK 854
TGDG ND PALKKAD+G AMGIAG+DV+K+A+D+IL DDNF SIV V GR ++D++ K
Sbjct: 715 TGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKK 774
Query: 855 FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLR 914
+ + LT N+ + PL V +L ++L D + +++LA E ++ R
Sbjct: 775 SIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKR 834
Query: 915 KPYGRNKPLISRTMMKNILGHAFYQLVVVFTL 946
+P P + + + ++ A+ Q+ ++ L
Sbjct: 835 QP---RNPKTDKLVNERLISMAYGQIGMIQAL 863
Score = 70.1 bits (170), Expect = 1e-11
Identities = 51/156 (32%), Positives = 85/156 (54%), Gaps = 13/156 (8%)
Query: 144 EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVIRGGQV 202
EEE + + ++ ++LS V V++ F+ + + K + ++S + Q+ VIR G+
Sbjct: 122 EEEPQNDNLYL---GVVLSAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEK 177
Query: 203 IQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLD---KDPL 259
+ I ++ VGD+ +VK GD +PAD +I N K+D SSLTGES+ +S D ++PL
Sbjct: 178 MSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPL 237
Query: 260 -----LLSGTHVMEGSGRMVVTAVGVNSQTGIIFTL 290
T+ +EG+ R +V G + G I TL
Sbjct: 238 ETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATL 273
>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo
sapiens]
Length = 1029
Score = 230 bits (587), Expect = 5e-60
Identities = 179/565 (31%), Positives = 282/565 (49%), Gaps = 64/565 (11%)
Query: 420 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 479
F+IG+ +V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGT
Sbjct: 331 FLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 388
Query: 480 LTMNRMTVVQAYINEKHYKKVPEPEAIPPNILS-----YLVTGISVNC-----AYTSKIL 529
LT NRMTV + + Y+ E +++ I+ C +IL
Sbjct: 389 LTQNRMTVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEIL 448
Query: 530 PPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVL 589
P K G+ +E ALL + ++R + P+ A FNS K ++
Sbjct: 449 PIAKRA----TTGDASESALLKFIEQSYSSVAEMREKNPKVA---EIPFNSTNKYQMSIH 501
Query: 590 KNSDGS--YRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRT 647
D S + + KGA E IL+ C L NG+ ++ +E + G R
Sbjct: 502 LREDSSQTHVLMMKGAPERILEFCSTFL-LNGQEYSMNDEMKEAFQNAYLE-LGGLGERV 559
Query: 648 ICLAFRDFPAGEPEPEWDNENDI---VTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITV 704
+ F + P+ + N ++I + L + ++ + DP R VPDA+ KC+ AGI V
Sbjct: 560 LGFCFLNLPSSFSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKV 619
Query: 705 RMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIR------------------NE 746
MVTGD+ TA+AIA GI+ G + ++ R++ E
Sbjct: 620 IMVTGDHPITAKAIAKGVGIISEGTE----TAEEVAARLKIPISKVDASAAKAIVVHGAE 675
Query: 747 KGEIEQERIDKI---WPKLRVLARSSPTDKHTLVKGIIDSTVSDQR--QVVAVTGDGTND 801
+I+ +++D+I P++ V AR+SP K +V+G QR VVAVTGDG ND
Sbjct: 676 LKDIQSKQLDQILQNHPEI-VFARTSPQQKLIIVEGC-------QRLGAVVAVTGDGVND 727
Query: 802 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 861
PALKKAD+G AMGI+G+DV+K+A+D+IL DDNF SIV V GR ++D++ K + + LT
Sbjct: 728 SPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLT 787
Query: 862 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNK 921
N+ + + PL + +L ++L D + +++LA E ++ R P
Sbjct: 788 SNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIMKRLP---RN 844
Query: 922 PLISRTMMKNILGHAFYQLVVVFTL 946
P + ++G A+ Q+ ++ L
Sbjct: 845 PKTDNLVNHRLIGMAYGQIGMIQAL 869
Score = 74.3 bits (181), Expect = 6e-13
Identities = 51/142 (35%), Positives = 84/142 (59%), Gaps = 10/142 (7%)
Query: 158 AILLSVVCVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVIRGGQVIQIPVADITVGDIA 216
+I+LSVV V++ F+ + + K + ++S + Q+ VIRGG+ +QI V ++ +GD+
Sbjct: 141 SIVLSVV-VIVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLV 199
Query: 217 QVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLD---KDPL-----LLSGTHVME 268
++K GD +PAD LI K+D SSLTGES+ +S D ++PL T+ +E
Sbjct: 200 EIKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVE 259
Query: 269 GSGRMVVTAVGVNSQTGIIFTL 290
G+ R +V A G ++ G I +L
Sbjct: 260 GTARGIVIATGDSTVMGRIASL 281
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,951,323
Number of Sequences: 37866
Number of extensions: 2200438
Number of successful extensions: 12595
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 123
Number of HSP's successfully gapped in prelim test: 117
Number of HSP's that attempted gapping in prelim test: 10689
Number of HSP's gapped (non-prelim): 1439
length of query: 1220
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1106
effective length of database: 13,930,794
effective search space: 15407458164
effective search space used: 15407458164
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.