Search of human proteins with 47933379

Search of human proteins with 47933379

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|47933379 N-ethylmaleimide-sensitive factor attachment
protein, alpha [Homo sapiens]
         (295 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|47933379 N-ethylmaleimide-sensitive factor attachment protein...   587   e-168
gi|44917606 N-ethylmaleimide-sensitive factor attachment protein...   506   e-143
gi|4505331 N-ethylmaleimide-sensitive factor attachment protein,...    60   2e-09
gi|55743151 WD repeat domain 19 [Homo sapiens]                         36   0.046
gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap...    30   1.9  
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]         30   3.3  
gi|145386551 SH3 domain and tetratricopeptide repeats 1 [Homo sa...    30   3.3  
gi|122937345 myosin VB [Homo sapiens]                                  29   5.6  
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    29   5.6  
gi|28460688 taxilin [Homo sapiens]                                     29   5.6  
gi|83415184 transmembrane and tetratricopeptide repeat containin...    29   5.6  
gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Hom...    28   7.4  
gi|4506453 retinol-binding protein 3 precursor [Homo sapiens]          28   7.4  
gi|126032338 ryanodine receptor 3 [Homo sapiens]                       28   7.4  
gi|33589814 zyg-11 homolog B (C. elegans)-like [Homo sapiens]          28   9.6  
gi|38373673 synaptonemal complex protein 2 [Homo sapiens]              28   9.6  

>gi|47933379 N-ethylmaleimide-sensitive factor attachment protein,
           alpha [Homo sapiens]
          Length = 295

 Score =  587 bits (1514), Expect = e-168
 Identities = 295/295 (100%), Positives = 295/295 (100%)

Query: 1   MDNSGKEAEAMALLAEAERKVKNSQSFFSGLFGGSSKIEEACEIYARAANMFKMAKNWSA 60
           MDNSGKEAEAMALLAEAERKVKNSQSFFSGLFGGSSKIEEACEIYARAANMFKMAKNWSA
Sbjct: 1   MDNSGKEAEAMALLAEAERKVKNSQSFFSGLFGGSSKIEEACEIYARAANMFKMAKNWSA 60

Query: 61  AGNAFCQAAQLHLQLQSKHDAATCFVDAGNAFKKADPQEAINCLMRAIEIYTDMGRFTIA 120
           AGNAFCQAAQLHLQLQSKHDAATCFVDAGNAFKKADPQEAINCLMRAIEIYTDMGRFTIA
Sbjct: 61  AGNAFCQAAQLHLQLQSKHDAATCFVDAGNAFKKADPQEAINCLMRAIEIYTDMGRFTIA 120

Query: 121 AKHHISIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAALLEQYQK 180
           AKHHISIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAALLEQYQK
Sbjct: 121 AKHHISIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAALLEQYQK 180

Query: 181 AIDIYEQVGTNAMDSPLLKYSAKDYFFKAALCHFCIDMLNAKLAVQKYEELFPAFSDSRE 240
           AIDIYEQVGTNAMDSPLLKYSAKDYFFKAALCHFCIDMLNAKLAVQKYEELFPAFSDSRE
Sbjct: 181 AIDIYEQVGTNAMDSPLLKYSAKDYFFKAALCHFCIDMLNAKLAVQKYEELFPAFSDSRE 240

Query: 241 CKLMKKLLEAHEEQNVDSYTESVKEYDSISRLDQWLTTMLLRIKKTIQGDEEDLR 295
           CKLMKKLLEAHEEQNVDSYTESVKEYDSISRLDQWLTTMLLRIKKTIQGDEEDLR
Sbjct: 241 CKLMKKLLEAHEEQNVDSYTESVKEYDSISRLDQWLTTMLLRIKKTIQGDEEDLR 295


>gi|44917606 N-ethylmaleimide-sensitive factor attachment protein,
           beta [Homo sapiens]
          Length = 298

 Score =  506 bits (1302), Expect = e-143
 Identities = 246/292 (84%), Positives = 274/292 (93%)

Query: 1   MDNSGKEAEAMALLAEAERKVKNSQSFFSGLFGGSSKIEEACEIYARAANMFKMAKNWSA 60
           MDN+GKE EA+ L+AEAE++VK S SF  GLFGG+++IEEACE+Y RAANMFKMAKNWSA
Sbjct: 1   MDNAGKEREAVQLMAEAEKRVKASHSFLRGLFGGNTRIEEACEMYTRAANMFKMAKNWSA 60

Query: 61  AGNAFCQAAQLHLQLQSKHDAATCFVDAGNAFKKADPQEAINCLMRAIEIYTDMGRFTIA 120
           AGNAFCQAA+LH+QLQSKHD+AT FVDAGNA+KKADPQEAINCL  AI+IYTDMGRFTIA
Sbjct: 61  AGNAFCQAAKLHMQLQSKHDSATSFVDAGNAYKKADPQEAINCLNAAIDIYTDMGRFTIA 120

Query: 121 AKHHISIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAALLEQYQK 180
           AKHHI+IAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVA YAA LEQYQK
Sbjct: 121 AKHHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQK 180

Query: 181 AIDIYEQVGTNAMDSPLLKYSAKDYFFKAALCHFCIDMLNAKLAVQKYEELFPAFSDSRE 240
           AI+IYEQVG N MD+PLLKYSAKDYFFKAALCHF +D LNAKLA++KYEE+FPAF+DSRE
Sbjct: 181 AIEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFPAFTDSRE 240

Query: 241 CKLMKKLLEAHEEQNVDSYTESVKEYDSISRLDQWLTTMLLRIKKTIQGDEE 292
           CKL+KKLLEAHEEQN ++YTE+VKE+DSISRLDQWLTTMLLRIKK+IQGD E
Sbjct: 241 CKLLKKLLEAHEEQNSEAYTEAVKEFDSISRLDQWLTTMLLRIKKSIQGDGE 292


>gi|4505331 N-ethylmaleimide-sensitive factor attachment protein,
           gamma [Homo sapiens]
          Length = 312

 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 61/266 (22%), Positives = 116/266 (43%), Gaps = 34/266 (12%)

Query: 9   EAMALLAEAERKVKNSQSFFSGLFGGSSKIEEACEIYARAANMFKMAKNWSAAGNAFCQA 68
           E +  LA+AE+ +K      +G        + A   Y +AA  FK AK +  A +A  + 
Sbjct: 8   EGLEHLAKAEKYLK------TGFLKWKPDYDSAASEYGKAAVAFKNAKQFEQAKDACLRE 61

Query: 69  AQLHLQLQSKHDAATCFVDAGNAFKKADP-QEAINCLMRAIEIYTDMGRFTIAAKHHISI 127
           A  H   ++   AA  +  AG   K+     EA+  + +A  +Y + G    AA      
Sbjct: 62  AVAHENNRALFHAAKAYEQAGMMLKEMQKLPEAVQLIEKASMMYLENGTPDTAAMALERA 121

Query: 128 AEIYETELVDIEKAIAHYEQSADYYKGEESN-------SSANKCLLKVAGYAALLEQYQK 180
            ++ E   VD EKA+  Y+Q+A+ ++ EE           A++ L++   +       QK
Sbjct: 122 GKLIEN--VDPEKAVQLYQQTANVFENEERLRQAVELLGKASRLLVRGRRFDEAALSIQK 179

Query: 181 AIDIYEQVGTNAMDSPLLKYSAKDYFFKAALCHFCI-----DMLNAKLAVQKYEELFPAF 235
             +IY+++                  +K  +    +     D + A+  V++   + P F
Sbjct: 180 EKNIYKEIENYPT------------CYKKTIAQVLVHLHRNDYVAAERCVRESYSI-PGF 226

Query: 236 SDSRECKLMKKLLEAHEEQNVDSYTE 261
           + S +C  +++LLE +++Q+ D  ++
Sbjct: 227 NGSEDCAALEQLLEGYDQQDQDQVSD 252


>gi|55743151 WD repeat domain 19 [Homo sapiens]
          Length = 1342

 Score = 35.8 bits (81), Expect = 0.046
 Identities = 54/272 (19%), Positives = 101/272 (37%), Gaps = 49/272 (18%)

Query: 32   FGGSSKIEEACEIYARAANMFKMAKNWSAAGNAF--CQAAQLHLQLQSKHDAATCFVDAG 89
            F  ++++ E    Y +AA+++  +KNW+  G+      + ++HLQ     +A   + +A 
Sbjct: 856  FSEAAQLYEKGLYYDKAASVYIRSKNWAKVGDLLPHVSSPKIHLQYAKAKEADGRYKEAV 915

Query: 90   NAFKKA---------------DPQEAINCLMR---------AIEIYTDMG---------- 115
             A++ A               +P++A+N +               +  +G          
Sbjct: 916  VAYENAKQWQSVIRIYLDHLNNPEKAVNIVRETQSLDGAKMVARFFLQLGDYGSAIQFLV 975

Query: 116  -------RFTIAAKHHISIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKV 168
                    FT+A +H  +  EIY   +   +     Y+  A Y++GE+    A K  L  
Sbjct: 976  MSKCNNEAFTLAQQH--NKMEIYADIIGSEDTTNEDYQSIALYFEGEKRYLQAGKFFLLC 1033

Query: 169  AGYAALLEQYQKAIDIYEQVGTNAMDSPLLKYSAKDYFFKAALCHFCIDMLNAKLAVQKY 228
              Y+  L+ + K     + V        +    AKD      L    +   +      KY
Sbjct: 1034 GQYSRALKHFLKCPSSEDNVAIEMAIETV--GQAKDELLTNQLIDHLLGENDGMPKDAKY 1091

Query: 229  -EELFPAFSDSRECKLMKKLLEAHEEQNVDSY 259
               L+ A    RE      ++ A EEQ+  +Y
Sbjct: 1092 LFRLYMALKQYREA-AQTAIIIAREEQSAGNY 1122


>gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo
           sapiens]
          Length = 504

 Score = 30.4 bits (67), Expect = 1.9
 Identities = 22/98 (22%), Positives = 47/98 (47%), Gaps = 10/98 (10%)

Query: 198 LKYSAKDYFFKAALCHFCIDMLNAKLAVQKYEELFPAFSDSREC-------KLMKKLLEA 250
           LK    + F+K +  ++ +   + +L++ +  E      D + C       K + KL+E+
Sbjct: 217 LKNDNTEAFYKISTLYYQLG--DHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIES 274

Query: 251 HEEQNVDS-YTESVKEYDSISRLDQWLTTMLLRIKKTI 287
            EE   D  YT++  +Y+S+ + +  +    +R K+ I
Sbjct: 275 AEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERI 312


>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
          Length = 2481

 Score = 29.6 bits (65), Expect = 3.3
 Identities = 36/174 (20%), Positives = 68/174 (39%), Gaps = 30/174 (17%)

Query: 39   EEACEIYARAANMFKMAKNWSAAGNAFCQAAQLHLQLQSKHDAATCFV-------DAGNA 91
            EEA + Y +  ++ +          A+      H  + S   A  CF        + G A
Sbjct: 894  EEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHELGEA 953

Query: 92   FKKADP--------------QEAINCLMRAIEIYTDMGRFTIAAKHHISIAEIYETELVD 137
            F KA                ++AI+CL R + I  DM    + +     +  +Y+ ++ +
Sbjct: 954  FNKAQAYGELGSLHSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQ-QMGE 1012

Query: 138  IEKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAAL----LEQYQKAIDIYEQ 187
             + A+ +++   D    EE+N+    C  +  G   L    L  +++A+   EQ
Sbjct: 1013 YDTALQYHQ--LDLQIAEETNNPT--CQGRAYGNLGLTYESLGTFERAVVYQEQ 1062


>gi|145386551 SH3 domain and tetratricopeptide repeats 1 [Homo
            sapiens]
          Length = 1336

 Score = 29.6 bits (65), Expect = 3.3
 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 1/80 (1%)

Query: 96   DPQEAINCLMRAIEIYTDMGRFTIAAKHHISIAEIYETELVDIEKAIAHYEQSADYYKGE 155
            DP +A      A+    D+G      K +  +A IY   L+D EK++  Y Q A  +  E
Sbjct: 1252 DPFDAAGYYQLALAAAVDLGNKKAQLKIYTRLATIYHNFLLDREKSLFFY-QKARTFATE 1310

Query: 156  ESNSSANKCLLKVAGYAALL 175
             +    N   L + G+A  L
Sbjct: 1311 LNVRRVNLPPLPLCGWAPWL 1330


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 40/156 (25%), Positives = 67/156 (42%), Gaps = 16/156 (10%)

Query: 131  YETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAALLEQYQKAIDIYEQVGT 190
            Y  E+  ++K + HY+QS     GE+++    +   +V      L++      I E   +
Sbjct: 955  YTMEVERLKKELVHYQQS----PGEDTSLRLQE---EVESLRTELQRAHSERKILEDAHS 1007

Query: 191  NAMDSPLLKYSAKDYFFKAALCHFCIDMLNAKLAVQKYEELFPAFSDSRECKLMKKLLEA 250
               D   L+    D   + AL     + LN ++  Q  +E      +S +  LMKK LE 
Sbjct: 1008 REKDE--LRKRVADLEQENALLKDEKEQLNNQILCQSKDEF---AQNSVKENLMKKELE- 1061

Query: 251  HEEQNVDSYTESVKEYDSISRLDQWLTTMLLRIKKT 286
             EE++   Y   VKEY  + +    L   +  IK+T
Sbjct: 1062 -EERS--RYQNLVKEYSQLEQRYDNLRDEMTIIKQT 1094


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 11/96 (11%)

Query: 132  ETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAALLEQYQKAIDIYEQVGTN 191
            + EL   E+A  H EQ  D    E +NS++ K        +ALL++ ++      Q+   
Sbjct: 1693 QEELASSERARRHAEQERDELADEITNSASGK--------SALLDEKRRLEARIAQLEEE 1744

Query: 192  AMDSPLLKYSAKDYFFKAALCHFCIDMLNAKLAVQK 227
              +         D F K  L    +D LNA+LA ++
Sbjct: 1745 LEEEQSNMELLNDRFRKTTL---QVDTLNAELAAER 1777


>gi|28460688 taxilin [Homo sapiens]
          Length = 546

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 17/53 (32%), Positives = 30/53 (56%), Gaps = 2/53 (3%)

Query: 234 AFSDSRECKLMKKLLEAHEEQNVDSYTESVKEY-DSISRLDQWLTTMLLRIKK 285
           A    R C+LMK+  E H +Q +  YTE  +E+ +++S+  +  TT    ++K
Sbjct: 366 AVESQRMCELMKQQ-ETHLKQQLALYTEKFEEFQNTLSKSSEVFTTFKQEMEK 417


>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
           [Homo sapiens]
          Length = 774

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 50/206 (24%), Positives = 81/206 (39%), Gaps = 65/206 (31%)

Query: 41  ACEIYARAA----NMFKMAKNWSAAGNAFCQAAQLHLQLQSKHDAATCFVDAGNAFKKAD 96
           A ++Y R A    N+  + ++ + A   + +A QLH Q    H+ A    + GN  K  +
Sbjct: 401 ALKLYPRHASALNNLGTLTRDTAEAKMYYQRALQLHPQ----HNRA--LFNLGNLLKSQE 454

Query: 97  P-QEAINCLMRAI-------EIYTDMGRFTIAAKHHISIAEIYETE-------------- 134
             +EAI  L  +I       + Y+ +       +      EIY+T               
Sbjct: 455 KKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNY 514

Query: 135 ---LVDI---EKAIAHYEQS--------------ADYYKGEESNSSAN---KCLLKVAGY 171
              LVD    EKA+AHY+Q+                 Y+    NS A    K  L+VA  
Sbjct: 515 GVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHK 574

Query: 172 AALLE----------QYQKAIDIYEQ 187
           A +L           +Y++A+ IY++
Sbjct: 575 AEILSPLGALYYNTGRYEEALQIYQE 600


>gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Homo
           sapiens]
          Length = 420

 Score = 28.5 bits (62), Expect = 7.4
 Identities = 32/149 (21%), Positives = 60/149 (40%), Gaps = 25/149 (16%)

Query: 153 KGEESN-----SSANKCLLKVAGYAALLEQYQKAIDIYEQVGTNAMDSPLLKYSAKDYFF 207
           K EE N        NK L     Y A +  Y  AI +  ++       PLL       + 
Sbjct: 284 KEEEKNPEWLKDKGNK-LFATENYLAAINAYNLAIRLNNKM-------PLL-------YL 328

Query: 208 KAALCHFCIDMLNAKL--AVQKYEELFPAFSDSRECKLMKKLLEAHEEQNVDSYTESVKE 265
             A CH  +  L+  +  + +  E L P  +D+   ++   +        ++ Y E +++
Sbjct: 329 NRAACHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQD 388

Query: 266 YDSISRLDQWLTTMLL---RIKKTIQGDE 291
           Y++  ++D     + +   +I+  IQG E
Sbjct: 389 YEAALKIDPSNKIVQIDAEKIRNVIQGTE 417


>gi|4506453 retinol-binding protein 3 precursor [Homo sapiens]
          Length = 1247

 Score = 28.5 bits (62), Expect = 7.4
 Identities = 13/36 (36%), Positives = 22/36 (61%)

Query: 172 AALLEQYQKAIDIYEQVGTNAMDSPLLKYSAKDYFF 207
           A +L+Q ++AI + E+ G  A+D   L+    D+FF
Sbjct: 243 AHILKQMRRAIVVGERTGGGALDLRKLRIGESDFFF 278


>gi|126032338 ryanodine receptor 3 [Homo sapiens]
          Length = 4870

 Score = 28.5 bits (62), Expect = 7.4
 Identities = 28/111 (25%), Positives = 49/111 (44%), Gaps = 20/111 (18%)

Query: 146  EQSADYYKGEESNSSANKCLLKVAGYAALLEQYQKAIDIYEQVGTNAMDSPLLKYSAKDY 205
            E+ A+Y   E +     +C  KV    A    + K ++IY+        + LL Y A+++
Sbjct: 4359 EEQAEYLWTEVTKKKKRRCGQKVEKPEAFTANFFKGLEIYQ--------TKLLHYLARNF 4410

Query: 206  F---FKAALCHFCID--MLNAKLAVQKYEE-------LFPAFSDSRECKLM 244
            +   F A    F I+  +L  K+  +  EE       L+ +F+D  E + M
Sbjct: 4411 YNLRFLALFVAFAINFILLFYKVTEEPLEEETEDVANLWNSFNDEEEEEAM 4461


>gi|33589814 zyg-11 homolog B (C. elegans)-like [Homo sapiens]
          Length = 766

 Score = 28.1 bits (61), Expect = 9.6
 Identities = 16/70 (22%), Positives = 34/70 (48%), Gaps = 6/70 (8%)

Query: 204 DYFFKAALC----HFCIDMLNAKLAVQKYEELFPAFSDSRECKLMKKLLEAHEEQNVDSY 259
           D F  + +C    +  ++++NA    + +E  F  FSD R  +L +  +   E+   D  
Sbjct: 39  DIFLPSEICDRLVNEYVELVNAACNFEPHESFFSLFSDPRSTRLTR--IHLREDLVQDQD 96

Query: 260 TESVKEYDSI 269
            E++++ D +
Sbjct: 97  LEAIRKQDLV 106


>gi|38373673 synaptonemal complex protein 2 [Homo sapiens]
          Length = 1530

 Score = 28.1 bits (61), Expect = 9.6
 Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 8/94 (8%)

Query: 183 DIYEQVGTNAMDSPLLKYSAKDYFFKAALCHFCIDMLNAKLAVQKYEELFPAFSDSRECK 242
           D+Y     N  D P++K   ++  F+A     C D     +  + ++EL  +        
Sbjct: 869 DVYN-FNLNGADDPIIKLGIQE--FQATAKEACADRSIRLVGPRNHDELKSSVKTKD--- 922

Query: 243 LMKKLLEAHEEQNVDSYTESVKEYDSISRLDQWL 276
             KK++  H+++N+ S TE+    D       WL
Sbjct: 923 --KKIITNHQKKNLFSDTETEYRCDDSKTDISWL 954


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.129    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,449,611
Number of Sequences: 37866
Number of extensions: 354528
Number of successful extensions: 1119
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1109
Number of HSP's gapped (non-prelim): 19
length of query: 295
length of database: 18,247,518
effective HSP length: 102
effective length of query: 193
effective length of database: 14,385,186
effective search space: 2776340898
effective search space used: 2776340898
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.