BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|47778923 cytochrome b5 reductase b5R.2 [Homo sapiens] (276 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|47778923 cytochrome b5 reductase b5R.2 [Homo sapiens] 571 e-163 gi|49574502 cytochrome b5 reductase 1 [Homo sapiens] 354 5e-98 gi|4503327 cytochrome b5 reductase 3 isoform m [Homo sapiens] 350 1e-96 gi|193794826 cytochrome b5 reductase 3 isoform s [Homo sapiens] 350 1e-96 gi|6552328 cytochrome b5 reductase 3 isoform s [Homo sapiens] 350 1e-96 gi|134133308 cytochrome b5 reductase-like [Homo sapiens] 105 6e-23 gi|84875541 cytochrome b5 reductase 4 [Homo sapiens] 95 6e-20 gi|19923907 oxidoreductase NAD-binding domain containing 1 [Homo... 49 6e-06 gi|110611172 amnionless protein precursor [Homo sapiens] 31 1.3 gi|169790958 methionine synthase reductase isoform 1 [Homo sapiens] 30 3.0 gi|169790956 methionine synthase reductase isoform 2 [Homo sapiens] 30 3.0 gi|140561070 RIM-binding protein 2 [Homo sapiens] 28 6.7 gi|27734935 solute carrier family 9 (sodium/hydrogen exchanger),... 28 8.7 >gi|47778923 cytochrome b5 reductase b5R.2 [Homo sapiens] Length = 276 Score = 571 bits (1471), Expect = e-163 Identities = 276/276 (100%), Positives = 276/276 (100%) Query: 1 MNSRRREPITLQDPEAKYPLPLIEKEKISHNTRRFRFGLPSPDHVLGLPVGNYVQLLAKI 60 MNSRRREPITLQDPEAKYPLPLIEKEKISHNTRRFRFGLPSPDHVLGLPVGNYVQLLAKI Sbjct: 1 MNSRRREPITLQDPEAKYPLPLIEKEKISHNTRRFRFGLPSPDHVLGLPVGNYVQLLAKI 60 Query: 61 DNELVVRAYTPVSSDDDRGFVDLIIKIYFKNVHPQYPEGGKMTQYLENMKIGETIFFRGP 120 DNELVVRAYTPVSSDDDRGFVDLIIKIYFKNVHPQYPEGGKMTQYLENMKIGETIFFRGP Sbjct: 61 DNELVVRAYTPVSSDDDRGFVDLIIKIYFKNVHPQYPEGGKMTQYLENMKIGETIFFRGP 120 Query: 121 RGRLFYHGPGNLGIRPDQTSEPKKTLADHLGMIAGGTGITPMLQLIRHITKDPSDRTRMS 180 RGRLFYHGPGNLGIRPDQTSEPKKTLADHLGMIAGGTGITPMLQLIRHITKDPSDRTRMS Sbjct: 121 RGRLFYHGPGNLGIRPDQTSEPKKTLADHLGMIAGGTGITPMLQLIRHITKDPSDRTRMS 180 Query: 181 LIFANQTEEDILVRKELEEIARTHPDQFNLWYTLDRPPIGWKYSSGFVTADMIKEHLPPP 240 LIFANQTEEDILVRKELEEIARTHPDQFNLWYTLDRPPIGWKYSSGFVTADMIKEHLPPP Sbjct: 181 LIFANQTEEDILVRKELEEIARTHPDQFNLWYTLDRPPIGWKYSSGFVTADMIKEHLPPP 240 Query: 241 AKSTLILVCGPPPLIQTAAHPNLEKLGYTQDMIFTY 276 AKSTLILVCGPPPLIQTAAHPNLEKLGYTQDMIFTY Sbjct: 241 AKSTLILVCGPPPLIQTAAHPNLEKLGYTQDMIFTY 276 >gi|49574502 cytochrome b5 reductase 1 [Homo sapiens] Length = 305 Score = 354 bits (908), Expect = 5e-98 Identities = 160/272 (58%), Positives = 210/272 (77%) Query: 5 RREPITLQDPEAKYPLPLIEKEKISHNTRRFRFGLPSPDHVLGLPVGNYVQLLAKIDNEL 64 RR +TL DP KY L L++K +SHNT+RFRF LP+ H LGLPVG ++ L +ID L Sbjct: 34 RRPQVTLLDPNEKYLLRLLDKTTVSHNTKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSL 93 Query: 65 VVRAYTPVSSDDDRGFVDLIIKIYFKNVHPQYPEGGKMTQYLENMKIGETIFFRGPRGRL 124 V+R YTPV+SD+D+G+VDL+IK+Y K VHP++PEGGKM+QYL+++K+G+ + FRGP G L Sbjct: 94 VIRPYTPVTSDEDQGYVDLVIKVYLKGVHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLL 153 Query: 125 FYHGPGNLGIRPDQTSEPKKTLADHLGMIAGGTGITPMLQLIRHITKDPSDRTRMSLIFA 184 Y G G+ I+P++ S P+ +A LGMIAGGTGITPMLQLIR I K P D T+ L+FA Sbjct: 154 TYTGKGHFNIQPNKKSPPEPRVAKKLGMIAGGTGITPMLQLIRAILKVPEDPTQCFLLFA 213 Query: 185 NQTEEDILVRKELEEIARTHPDQFNLWYTLDRPPIGWKYSSGFVTADMIKEHLPPPAKST 244 NQTE+DI++R++LEE+ +P++F LW+TLD PP W YS GFVTADMI+EHLP P Sbjct: 214 NQTEKDIILREDLEELQARYPNRFKLWFTLDHPPKDWAYSKGFVTADMIREHLPAPGDDV 273 Query: 245 LILVCGPPPLIQTAAHPNLEKLGYTQDMIFTY 276 L+L+CGPPP++Q A HPNL+KLGY+Q M FTY Sbjct: 274 LVLLCGPPPMVQLACHPNLDKLGYSQKMRFTY 305 >gi|4503327 cytochrome b5 reductase 3 isoform m [Homo sapiens] Length = 301 Score = 350 bits (897), Expect = 1e-96 Identities = 163/273 (59%), Positives = 203/273 (74%) Query: 4 RRREPITLQDPEAKYPLPLIEKEKISHNTRRFRFGLPSPDHVLGLPVGNYVQLLAKIDNE 63 R ITL+ P+ KYPL LI++E ISH+TRRFRF LPSP H+LGLPVG ++ L A+ID Sbjct: 29 RSTPAITLESPDIKYPLRLIDREIISHDTRRFRFALPSPQHILGLPVGQHIYLSARIDGN 88 Query: 64 LVVRAYTPVSSDDDRGFVDLIIKIYFKNVHPQYPEGGKMTQYLENMKIGETIFFRGPRGR 123 LVVR YTP+SSDDD+GFVDL+IK+YFK+ HP++P GGKM+QYLE+M+IG+TI FRGP G Sbjct: 89 LVVRPYTPISSDDDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGL 148 Query: 124 LFYHGPGNLGIRPDQTSEPKKTLADHLGMIAGGTGITPMLQLIRHITKDPSDRTRMSLIF 183 L Y G G IRPD+ S P +GMIAGGTGITPMLQ+IR I KDP D T L+F Sbjct: 149 LVYQGKGKFAIRPDKKSNPIIRTVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLF 208 Query: 184 ANQTEEDILVRKELEEIARTHPDQFNLWYTLDRPPIGWKYSSGFVTADMIKEHLPPPAKS 243 ANQTE+DIL+R ELEE+ H +F LWYTLDR P W Y GFV +MI++HLPPP + Sbjct: 209 ANQTEKDILLRPELEELRNKHSARFKLWYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEE 268 Query: 244 TLILVCGPPPLIQTAAHPNLEKLGYTQDMIFTY 276 L+L+CGPPP+IQ A PNL+ +G+ + F + Sbjct: 269 PLVLMCGPPPMIQYACLPNLDHVGHPTERCFVF 301 >gi|193794826 cytochrome b5 reductase 3 isoform s [Homo sapiens] Length = 278 Score = 350 bits (897), Expect = 1e-96 Identities = 163/273 (59%), Positives = 203/273 (74%) Query: 4 RRREPITLQDPEAKYPLPLIEKEKISHNTRRFRFGLPSPDHVLGLPVGNYVQLLAKIDNE 63 R ITL+ P+ KYPL LI++E ISH+TRRFRF LPSP H+LGLPVG ++ L A+ID Sbjct: 6 RSTPAITLESPDIKYPLRLIDREIISHDTRRFRFALPSPQHILGLPVGQHIYLSARIDGN 65 Query: 64 LVVRAYTPVSSDDDRGFVDLIIKIYFKNVHPQYPEGGKMTQYLENMKIGETIFFRGPRGR 123 LVVR YTP+SSDDD+GFVDL+IK+YFK+ HP++P GGKM+QYLE+M+IG+TI FRGP G Sbjct: 66 LVVRPYTPISSDDDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGL 125 Query: 124 LFYHGPGNLGIRPDQTSEPKKTLADHLGMIAGGTGITPMLQLIRHITKDPSDRTRMSLIF 183 L Y G G IRPD+ S P +GMIAGGTGITPMLQ+IR I KDP D T L+F Sbjct: 126 LVYQGKGKFAIRPDKKSNPIIRTVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLF 185 Query: 184 ANQTEEDILVRKELEEIARTHPDQFNLWYTLDRPPIGWKYSSGFVTADMIKEHLPPPAKS 243 ANQTE+DIL+R ELEE+ H +F LWYTLDR P W Y GFV +MI++HLPPP + Sbjct: 186 ANQTEKDILLRPELEELRNKHSARFKLWYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEE 245 Query: 244 TLILVCGPPPLIQTAAHPNLEKLGYTQDMIFTY 276 L+L+CGPPP+IQ A PNL+ +G+ + F + Sbjct: 246 PLVLMCGPPPMIQYACLPNLDHVGHPTERCFVF 278 >gi|6552328 cytochrome b5 reductase 3 isoform s [Homo sapiens] Length = 278 Score = 350 bits (897), Expect = 1e-96 Identities = 163/273 (59%), Positives = 203/273 (74%) Query: 4 RRREPITLQDPEAKYPLPLIEKEKISHNTRRFRFGLPSPDHVLGLPVGNYVQLLAKIDNE 63 R ITL+ P+ KYPL LI++E ISH+TRRFRF LPSP H+LGLPVG ++ L A+ID Sbjct: 6 RSTPAITLESPDIKYPLRLIDREIISHDTRRFRFALPSPQHILGLPVGQHIYLSARIDGN 65 Query: 64 LVVRAYTPVSSDDDRGFVDLIIKIYFKNVHPQYPEGGKMTQYLENMKIGETIFFRGPRGR 123 LVVR YTP+SSDDD+GFVDL+IK+YFK+ HP++P GGKM+QYLE+M+IG+TI FRGP G Sbjct: 66 LVVRPYTPISSDDDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGL 125 Query: 124 LFYHGPGNLGIRPDQTSEPKKTLADHLGMIAGGTGITPMLQLIRHITKDPSDRTRMSLIF 183 L Y G G IRPD+ S P +GMIAGGTGITPMLQ+IR I KDP D T L+F Sbjct: 126 LVYQGKGKFAIRPDKKSNPIIRTVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLF 185 Query: 184 ANQTEEDILVRKELEEIARTHPDQFNLWYTLDRPPIGWKYSSGFVTADMIKEHLPPPAKS 243 ANQTE+DIL+R ELEE+ H +F LWYTLDR P W Y GFV +MI++HLPPP + Sbjct: 186 ANQTEKDILLRPELEELRNKHSARFKLWYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEE 245 Query: 244 TLILVCGPPPLIQTAAHPNLEKLGYTQDMIFTY 276 L+L+CGPPP+IQ A PNL+ +G+ + F + Sbjct: 246 PLVLMCGPPPMIQYACLPNLDHVGHPTERCFVF 278 >gi|134133308 cytochrome b5 reductase-like [Homo sapiens] Length = 315 Score = 105 bits (261), Expect = 6e-23 Identities = 79/270 (29%), Positives = 133/270 (49%), Gaps = 33/270 (12%) Query: 13 DPEAKYPLPLIEKEKISHNTRRFRFGLPSPDHVLGLPVGNYVQLLAKIDNELVVRAYTPV 72 +PE +I ++++ +T R RF LP LGL G ++ L +D+ + RAYTP+ Sbjct: 73 NPETFVAFCIIAMDRLTKDTYRVRFALPGNSQ-LGLRPGQHLILRGIVDDLEIQRAYTPI 131 Query: 73 SSDDDRGFVDLIIKIYFKNVHPQYPEGGKMTQYLENMKIGETIFFRGPRGRLFYHGPGNL 132 S + G+ +++IK Y + G M++Y+E+ ++G+T F+RGP G FY Sbjct: 132 SPANAEGYFEVLIKCY---------QMGLMSRYVESWRVGDTAFWRGPFGDFFY------ 176 Query: 133 GIRPDQTSEPKKTLADHLGMIAGGTGITPMLQLIRHITKDPSDRTRMSLIFANQTEEDIL 192 +P+Q E L ++A GTG+ PM+ +++ IT + +D T ++L+ +T E I Sbjct: 177 --KPNQYGE--------LLLLAAGTGLAPMVPILQSITDNENDETFVTLVGCFKTFESIY 226 Query: 193 VRKELEEIARTHPDQ--FNLWYTLDRPPIGWKYSS----GFVTADMIKEHLPPPAKSTLI 246 ++ L+E AR + F L + W Y G + D+IKE + + Sbjct: 227 LKTFLQEQARFWNVRTFFVLSQESSSEQLPWSYQEKTHFGHLGQDLIKELVSCCRRKPFA 286 Query: 247 LVCGPPPLIQTAAHPNLEKLGYTQDMIFTY 276 LVCG + A L G T+D F + Sbjct: 287 LVCGSAEFTKDIAR-CLLCAGLTEDSYFLF 315 >gi|84875541 cytochrome b5 reductase 4 [Homo sapiens] Length = 521 Score = 95.1 bits (235), Expect = 6e-20 Identities = 73/262 (27%), Positives = 124/262 (47%), Gaps = 29/262 (11%) Query: 22 LIEKEKISHNTRRFRFGLPSPDHVLGLPVGNYVQLLAKIDNELVVRAYTPVSSDDDRGFV 81 LI KE ++H+TR F LP H L +P+G +V L I +V+ YTPVS F Sbjct: 280 LISKEDVTHDTRLFCLMLPPSTH-LQVPIGQHVYLKLPITGTEIVKPYTPVSGSLLSEFK 338 Query: 82 DLIIK----IYFK-NVHPQYPEGGKMTQYLENMKIGETIFFRGPRGRLFYHGPGNLGIRP 136 + ++ IYF ++P G T L+ ++IG+ + P G N I Sbjct: 339 EPVLPNNKYIYFLIKIYPT----GLFTPELDRLQIGDFVSVSSPEG--------NFKISK 386 Query: 137 DQTSEPKKTLADHLGMIAGGTGITPMLQLIRHITKDPSDRTRMSLIFANQTEEDILVRKE 196 Q E L ++A GTG TPM++++ + D ++ L+F N+TE+DI+ R + Sbjct: 387 FQELED-------LFLLAAGTGFTPMVKILNYALTDIPSLRKVKLMFFNKTEDDIIWRSQ 439 Query: 197 LEEIARTHPDQFNLWYTLDRPPIGWKYSSGFVTADMIKEHLPP--PAKSTLILVCGPPPL 254 LE++A + ++ + L P W G ++ ++ E L L+ +CGP P Sbjct: 440 LEKLA-FKDKRLDVEFVLSAPISEWNGKQGHISPALLSEFLKRNLDKSKVLVCICGPVPF 498 Query: 255 IQTAAHPNLEKLGYTQDMIFTY 276 + L L ++++ I ++ Sbjct: 499 TEQGVR-LLHDLNFSKNEIHSF 519 >gi|19923907 oxidoreductase NAD-binding domain containing 1 [Homo sapiens] Length = 312 Score = 48.5 bits (114), Expect = 6e-06 Identities = 30/121 (24%), Positives = 63/121 (52%), Gaps = 18/121 (14%) Query: 149 HLGMIAGGTGITPMLQLIRH---ITKDPSDRTR------MSLIFANQTEEDILVRKELEE 199 +L +IAGG GI P+L ++RH + ++ +++ + L ++ + ++L +K + + Sbjct: 171 NLVLIAGGVGINPLLSILRHAADLLREQANKRNGYEIGTIKLFYSAKNTSELLFKKNILD 230 Query: 200 IARTHPDQF--NLWYTLDRPPIGWK----YSSGFVTADMIKEHLPPPAKSTLILVCGPPP 253 + P++ +L T I + + G +T I++H+ +K TL +CGPPP Sbjct: 231 LVNEFPEKIACSLHVTKQTTQINAELKPYITEGRITEKEIRDHI---SKETLFYICGPPP 287 Query: 254 L 254 + Sbjct: 288 M 288 >gi|110611172 amnionless protein precursor [Homo sapiens] Length = 453 Score = 30.8 bits (68), Expect = 1.3 Identities = 11/28 (39%), Positives = 17/28 (60%) Query: 115 IFFRGPRGRLFYHGPGNLGIRPDQTSEP 142 +F GRL +HGPG L + P+ ++P Sbjct: 181 VFLASRAGRLRFHGPGALSVGPEDCADP 208 >gi|169790958 methionine synthase reductase isoform 1 [Homo sapiens] Length = 698 Score = 29.6 bits (65), Expect = 3.0 Identities = 38/160 (23%), Positives = 59/160 (36%), Gaps = 21/160 (13%) Query: 127 HGPGNLGIRPDQTSEPKKTLADHLG--------MIAGGTGITPMLQLIRHITK----DPS 174 H + P + P+ T + HL M+ GTGI P + ++H K P Sbjct: 509 HEDSGKALAPKISISPRTTNSFHLPDDPSIPIIMVGPGTGIAPFIGFLQHREKLQEQHPD 568 Query: 175 DRTRMSLIF--ANQTEEDILVRKELEEIARTHPDQFNLWYTLDR-PPIGWKYSSGFVTAD 231 +F + D L RKEL + H +L + R P+G + + D Sbjct: 569 GNFGAMWLFFGCRHKDRDYLFRKELRHFLK-HGILTHLKVSFSRDAPVGEEEAPAKYVQD 627 Query: 232 MIKEHLPPPAKSTL-----ILVCGPPPLIQTAAHPNLEKL 266 I+ H A+ L I VCG + H L ++ Sbjct: 628 NIQLHGQQVARILLQENGHIYVCGDAKNMAKDVHDALVQI 667 >gi|169790956 methionine synthase reductase isoform 2 [Homo sapiens] Length = 725 Score = 29.6 bits (65), Expect = 3.0 Identities = 38/160 (23%), Positives = 59/160 (36%), Gaps = 21/160 (13%) Query: 127 HGPGNLGIRPDQTSEPKKTLADHLG--------MIAGGTGITPMLQLIRHITK----DPS 174 H + P + P+ T + HL M+ GTGI P + ++H K P Sbjct: 536 HEDSGKALAPKISISPRTTNSFHLPDDPSIPIIMVGPGTGIAPFIGFLQHREKLQEQHPD 595 Query: 175 DRTRMSLIF--ANQTEEDILVRKELEEIARTHPDQFNLWYTLDR-PPIGWKYSSGFVTAD 231 +F + D L RKEL + H +L + R P+G + + D Sbjct: 596 GNFGAMWLFFGCRHKDRDYLFRKELRHFLK-HGILTHLKVSFSRDAPVGEEEAPAKYVQD 654 Query: 232 MIKEHLPPPAKSTL-----ILVCGPPPLIQTAAHPNLEKL 266 I+ H A+ L I VCG + H L ++ Sbjct: 655 NIQLHGQQVARILLQENGHIYVCGDAKNMAKDVHDALVQI 694 >gi|140561070 RIM-binding protein 2 [Homo sapiens] Length = 1052 Score = 28.5 bits (62), Expect = 6.7 Identities = 15/35 (42%), Positives = 23/35 (65%), Gaps = 3/35 (8%) Query: 179 MSLIFANQTEEDILVR---KELEEIARTHPDQFNL 210 ++++ A Q E D+L + +ELEE RT +QFNL Sbjct: 19 LAVLSAKQQEIDLLQKSKVRELEEKCRTQSEQFNL 53 >gi|27734935 solute carrier family 9 (sodium/hydrogen exchanger), member 9 [Homo sapiens] Length = 645 Score = 28.1 bits (61), Expect = 8.7 Identities = 38/154 (24%), Positives = 57/154 (37%), Gaps = 17/154 (11%) Query: 115 IFFRGPRGRL-FYHGPGNLGIRPDQTSEPKKTLADHLGMIAGGTGITPMLQLIR-HITKD 172 + F G RG + F N +P Q L + G G TPML ++ + D Sbjct: 435 MMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWLQIRVGVD 494 Query: 173 PSDRTRMSLIFANQTEEDILVRKELEEIARTHPDQFNLWYTLDRPPIGWKYSSGFVTADM 232 + + +Q ++ E AR F +WY+ D KY +T Sbjct: 495 LDENLKEDPSSQHQEANNLDKNMTKAESARL----FRMWYSFDH-----KYLKPILT--- 542 Query: 233 IKEHLPPPAKSTLILVCGPPPLIQTAAHPNLEKL 266 H PP +TL CGP + T+ E+L Sbjct: 543 ---HSGPPLTTTLPEWCGPISRLLTSPQAYGEQL 573 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.141 0.429 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,462,621 Number of Sequences: 37866 Number of extensions: 617272 Number of successful extensions: 1298 Number of sequences better than 10.0: 13 Number of HSP's better than 10.0 without gapping: 9 Number of HSP's successfully gapped in prelim test: 4 Number of HSP's that attempted gapping in prelim test: 1283 Number of HSP's gapped (non-prelim): 13 length of query: 276 length of database: 18,247,518 effective HSP length: 101 effective length of query: 175 effective length of database: 14,423,052 effective search space: 2524034100 effective search space used: 2524034100 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.