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Search of human proteins with 4759246
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4759246 tumor necrosis factor receptor superfamily, member
18 isoform 1 precursor [Homo sapiens]
(241 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4759246 tumor necrosis factor receptor superfamily, member 18... 538 e-153
gi|23238197 tumor necrosis factor receptor superfamily, member 1... 512 e-145
gi|23238194 tumor necrosis factor receptor superfamily, member 1... 317 8e-87
gi|5730095 tumor necrosis factor receptor superfamily, member 9 ... 67 1e-11
gi|4507579 tumor necrosis factor receptor superfamily, member 4 ... 63 3e-10
gi|14790170 tumor necrosis factor receptor superfamily, member 6... 54 2e-07
gi|4507585 tumor necrosis factor receptor superfamily, member 6b... 54 2e-07
gi|4507565 tumor necrosis factor receptor superfamily, member 11... 52 4e-07
gi|148743793 osteoprotegerin precursor [Homo sapiens] 50 1e-06
gi|7657039 tumor necrosis factor receptor superfamily, member 21... 50 1e-06
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens] 46 3e-05
gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi... 45 7e-05
gi|4505039 lymphotoxin beta receptor [Homo sapiens] 44 1e-04
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens] 39 0.004
gi|66346695 fibrillin 2 precursor [Homo sapiens] 37 0.012
gi|239756792 PREDICTED: hypothetical protein [Homo sapiens] 37 0.015
gi|239751312 PREDICTED: hypothetical protein [Homo sapiens] 37 0.015
gi|239745809 PREDICTED: hypothetical protein [Homo sapiens] 37 0.015
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 36 0.034
gi|54400749 keratin associated protein 5-1 [Homo sapiens] 36 0.034
gi|60593038 keratin associated protein 5-4 [Homo sapiens] 35 0.045
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 35 0.058
gi|23200041 tumor necrosis factor receptor superfamily, member 1... 35 0.058
gi|29725609 epidermal growth factor receptor isoform a precursor... 34 0.099
gi|41327736 epidermal growth factor receptor isoform d precursor... 34 0.099
gi|41327734 epidermal growth factor receptor isoform c precursor... 34 0.099
gi|41327732 epidermal growth factor receptor isoform b precursor... 34 0.099
gi|65301164 very low density lipoprotein receptor isoform b [Hom... 34 0.13
gi|65301167 very low density lipoprotein receptor isoform a [Hom... 34 0.13
gi|11641231 ectodysplasin A receptor precursor [Homo sapiens] 34 0.13
>gi|4759246 tumor necrosis factor receptor superfamily, member 18
isoform 1 precursor [Homo sapiens]
Length = 241
Score = 538 bits (1386), Expect = e-153
Identities = 241/241 (100%), Positives = 241/241 (100%)
Query: 1 MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRD 60
MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRD
Sbjct: 1 MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRD 60
Query: 61 YPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTF 120
YPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTF
Sbjct: 61 YPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTF 120
Query: 121 SGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLGWLTVVLLAVAACVLLL 180
SGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLGWLTVVLLAVAACVLLL
Sbjct: 121 SGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLGWLTVVLLAVAACVLLL 180
Query: 181 TSAQLGLHIWQLRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLW 240
TSAQLGLHIWQLRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLW
Sbjct: 181 TSAQLGLHIWQLRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLW 240
Query: 241 V 241
V
Sbjct: 241 V 241
>gi|23238197 tumor necrosis factor receptor superfamily, member 18
isoform 3 precursor [Homo sapiens]
Length = 234
Score = 512 bits (1318), Expect = e-145
Identities = 233/241 (96%), Positives = 234/241 (97%), Gaps = 7/241 (2%)
Query: 1 MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRD 60
MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRD
Sbjct: 1 MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRD 60
Query: 61 YPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTF 120
YPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTF
Sbjct: 61 YPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTF 120
Query: 121 SGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLGWLTVVLLAVAACVLLL 180
SGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLGWLTVVLLAVAACVLLL
Sbjct: 121 SGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLGWLTVVLLAVAACVLLL 180
Query: 181 TSAQLGLHIWQLRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLW 240
TSAQLGLHIWQL R+TQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLW
Sbjct: 181 TSAQLGLHIWQL-------RKTQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLW 233
Query: 241 V 241
V
Sbjct: 234 V 234
>gi|23238194 tumor necrosis factor receptor superfamily, member 18
isoform 2 precursor [Homo sapiens]
Length = 255
Score = 317 bits (811), Expect = 8e-87
Identities = 134/134 (100%), Positives = 134/134 (100%)
Query: 1 MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRD 60
MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRD
Sbjct: 1 MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRD 60
Query: 61 YPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTF 120
YPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTF
Sbjct: 61 YPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTF 120
Query: 121 SGGHEGHCKPWTDC 134
SGGHEGHCKPWTDC
Sbjct: 121 SGGHEGHCKPWTDC 134
>gi|5730095 tumor necrosis factor receptor superfamily, member 9
precursor [Homo sapiens]
Length = 255
Score = 67.0 bits (162), Expect = 1e-11
Identities = 59/199 (29%), Positives = 84/199 (42%), Gaps = 34/199 (17%)
Query: 54 TTRCCRDYPG-----EECCSEWDCMC-VQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFS 107
T CR G +EC S + C P FHC C+ C C GQ + +G
Sbjct: 61 TCDICRQCKGVFRTRKECSSTSNAECDCTPGFHCLGAGCSMCEQD-CKQGQELTKKG--- 116
Query: 108 FGFQCIDCASGTFSGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPG----------- 156
C DC GTF+ G C+PWT+C+ G + G K + VC P
Sbjct: 117 ----CKDCCFGTFNDQKRGICRPWTNCSLDGKSVLVNGTKERDVVCGPSPADLSPGASSV 172
Query: 157 SPPA---EPLGWLTVV--LLAVAACVLLLTSAQLGLH---IWQLRSQCMWPRETQLLLEV 208
+PPA EP ++ LA+ + LL L L + + R + ++ + + V
Sbjct: 173 TPPAPAREPGHSPQIISFFLALTSTALLFLLFFLTLRFSVVKRGRKKLLYIFKQPFMRPV 232
Query: 209 PPS-TEDARSCQFPEEERG 226
+ ED SC+FPEEE G
Sbjct: 233 QTTQEEDGCSCRFPEEEEG 251
>gi|4507579 tumor necrosis factor receptor superfamily, member 4
precursor [Homo sapiens]
Length = 277
Score = 62.8 bits (151), Expect = 3e-10
Identities = 40/125 (32%), Positives = 50/125 (40%), Gaps = 6/125 (4%)
Query: 42 GTGTDARCCRVHTTRCCRDYPG--EECCSEWDCM-CVQPEFHCGDP---CCTTCRHHPCP 95
G G +RC R T C PG + S C C G CT + C
Sbjct: 49 GNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLRSGSERKQLCTATQDTVCR 108
Query: 96 PGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVP 155
G Q + G C C G FS G CKPWT+CT G T+ P + + +A+C
Sbjct: 109 CRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKPWTNCTLAGKHTLQPASNSSDAICED 168
Query: 156 GSPPA 160
PPA
Sbjct: 169 RDPPA 173
Score = 32.7 bits (73), Expect = 0.29
Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 6/62 (9%)
Query: 74 CVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGH-CKPWT 132
CV + D CC H C PG G+ S+ S C C G ++ CKP T
Sbjct: 31 CVGDTYPSNDRCC-----HECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCT 85
Query: 133 DC 134
C
Sbjct: 86 WC 87
>gi|14790170 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 53.5 bits (127), Expect = 2e-07
Identities = 34/110 (30%), Positives = 42/110 (38%), Gaps = 19/110 (17%)
Query: 46 DARCCRVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGK 105
+AR C R CR G F C H CPPG GV + G
Sbjct: 101 EARACHATHNRACRCRTG---------------FFAHAGFCL--EHASCPPGAGVIAPGT 143
Query: 106 FSFGFQCIDCASGTFSGGHEG--HCKPWTDCTQFGFLTVFPGNKTHNAVC 153
S QC C GTFS C+P +CT G PG+ +H+ +C
Sbjct: 144 PSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLC 193
>gi|4507585 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 53.5 bits (127), Expect = 2e-07
Identities = 34/110 (30%), Positives = 42/110 (38%), Gaps = 19/110 (17%)
Query: 46 DARCCRVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGK 105
+AR C R CR G F C H CPPG GV + G
Sbjct: 101 EARACHATHNRACRCRTG---------------FFAHAGFCL--EHASCPPGAGVIAPGT 143
Query: 106 FSFGFQCIDCASGTFSGGHEG--HCKPWTDCTQFGFLTVFPGNKTHNAVC 153
S QC C GTFS C+P +CT G PG+ +H+ +C
Sbjct: 144 PSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLC 193
>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
precursor [Homo sapiens]
Length = 616
Score = 52.4 bits (124), Expect = 4e-07
Identities = 36/123 (29%), Positives = 53/123 (43%), Gaps = 8/123 (6%)
Query: 72 CMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEG--HCK 129
C C +H C R+ C PG G Q + + C C +G FS C+
Sbjct: 112 CACTAG-YHWSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCR 170
Query: 130 PWTDCTQFGFLTVFPGNKTHNAVCVPG----SPPAEPLGWLT-VVLLAVAACVLLLTSAQ 184
PWT+CT G G + +AVC PP EP +L +++L + A V L+ +
Sbjct: 171 PWTNCTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAII 230
Query: 185 LGL 187
G+
Sbjct: 231 FGV 233
>gi|148743793 osteoprotegerin precursor [Homo sapiens]
Length = 401
Score = 50.4 bits (119), Expect = 1e-06
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
Query: 90 RHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSG--GHEGHCKPWTDCTQFGFLTVFPGNK 147
+H CPPG GV G C C G FS + C+ T+C+ FG L GN
Sbjct: 120 KHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNA 179
Query: 148 THNAVCVPGSPPAEPLG 164
TH+ +C S + G
Sbjct: 180 THDNICSGNSESTQKCG 196
>gi|7657039 tumor necrosis factor receptor superfamily, member 21
precursor [Homo sapiens]
Length = 655
Score = 50.4 bits (119), Expect = 1e-06
Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 5/85 (5%)
Query: 71 DCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEG--HC 128
+C C F C H CP G GV+ +G + +C CA GTFS C
Sbjct: 130 ECTCPPGMFQSNATCAP---HTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKC 186
Query: 129 KPWTDCTQFGFLTVFPGNKTHNAVC 153
K +TDC + + PG K + VC
Sbjct: 187 KAYTDCLSQNLVVIKPGTKETDNVC 211
>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
Length = 277
Score = 46.2 bits (108), Expect = 3e-05
Identities = 36/130 (27%), Positives = 46/130 (35%), Gaps = 11/130 (8%)
Query: 34 CGPGRLLLGTGTDARCCRVHTTRCCRDYPG----EECCSEWDCMCVQPE-FHCGDPCCTT 88
CG L + C H + C G ++ SE D +C E +HC C +
Sbjct: 62 CGESEFLDTWNRETHC---HQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACES 118
Query: 89 C-RHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGH--CKPWTDCTQFGFLTVFPG 145
C H C PG GV+ C C G FS C PWT C + G
Sbjct: 119 CVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETKDLVVQQAG 178
Query: 146 NKTHNAVCVP 155
+ VC P
Sbjct: 179 TNKTDVVCGP 188
>gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
sapiens]
Length = 461
Score = 44.7 bits (104), Expect = 7e-05
Identities = 33/113 (29%), Positives = 45/113 (39%), Gaps = 14/113 (12%)
Query: 55 TRCCRDYPGEECCSEWD---CMCVQPEFHCG----DPCCTTCRHHPCPPGQGVQSQGKFS 107
+RC D + C+ C C +P ++C + C C PG GV G +
Sbjct: 98 SRCSSDQVETQACTREQNRICTC-RPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTET 156
Query: 108 FGFQCIDCASGTFSG--GHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSP 158
C CA GTFS C+P C + PGN + +AVC SP
Sbjct: 157 SDVVCKPCAPGTFSNTTSSTDICRPHQICN----VVAIPGNASMDAVCTSTSP 205
>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
Length = 435
Score = 43.9 bits (102), Expect = 1e-04
Identities = 37/143 (25%), Positives = 53/143 (37%), Gaps = 16/143 (11%)
Query: 34 CGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHP 93
C P ++G A C T+C R PG C + W C E
Sbjct: 101 CRPCDPVMGLEEIAPCTSKRKTQC-RCQPGMFCAA-WALECTHCELLSD----------- 147
Query: 94 CPPGQGVQSQGKFSFGFQ-CIDCASGTF--SGGHEGHCKPWTDCTQFGFLTVFPGNKTHN 150
CPPG + + + G C+ C +G F + C+P T C G + PG +
Sbjct: 148 CPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSD 207
Query: 151 AVCVPGSPPAEPLGWLTVVLLAV 173
C P P T+++LAV
Sbjct: 208 TTCKNPLEPLPPEMSGTMLMLAV 230
>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
Length = 203
Score = 38.9 bits (89), Expect = 0.004
Identities = 31/107 (28%), Positives = 39/107 (36%), Gaps = 11/107 (10%)
Query: 34 CGPGRLLLGTGTDARCCRVHTTRCCRDYPG----EECCSEWDCMCVQPE-FHCGDPCCTT 88
CG L + C H + C G ++ SE D +C E +HC C +
Sbjct: 62 CGESEFLDTWNRETHC---HQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACES 118
Query: 89 C-RHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEG--HCKPWT 132
C H C PG GV+ C C G FS C PWT
Sbjct: 119 CVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWT 165
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 37.4 bits (85), Expect = 0.012
Identities = 27/87 (31%), Positives = 32/87 (36%), Gaps = 22/87 (25%)
Query: 34 CGPGRLLLGTGTDARCCRVHTTR-----------CCRDYPGEECCSEWDCMCVQPEFHCG 82
C PG L G D R C R C R +PG SE C C P++ G
Sbjct: 684 CPPG---LAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSE--CCCANPDYGFG 738
Query: 83 DPCCTTCRHHPCPPGQGVQSQGKFSFG 109
+PC PCP + G S G
Sbjct: 739 EPC------QPCPAKNSAEFHGLCSSG 759
Score = 27.7 bits (60), Expect = 9.3
Identities = 26/92 (28%), Positives = 31/92 (33%), Gaps = 32/92 (34%)
Query: 34 CGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWD---CMCVQPEFHCGDPCC---- 86
C G L GTG R C D E+C +WD C+ P D CC
Sbjct: 982 CPEGLTLDGTG-----------RVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVG 1030
Query: 87 ----TTCRHHP----------CPPGQGVQSQG 104
T C P CP G G ++G
Sbjct: 1031 AAWGTECEECPKPGTKEYETLCPRGAGFANRG 1062
>gi|239756792 PREDICTED: hypothetical protein [Homo sapiens]
Length = 188
Score = 37.0 bits (84), Expect = 0.015
Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 7/53 (13%)
Query: 47 ARCCRVH--TTRCCRDYP-GEECCSEWDC--MCVQPEFHCGDPCCTTCRHHPC 94
A CC+ +T CC+ G CC + C C QP CG CC C H C
Sbjct: 73 ASCCQPSCCSTPCCQPTCCGSSCCGQTSCGSSCCQPI--CGSSCCQPCCHPTC 123
Score = 28.1 bits (61), Expect = 7.1
Identities = 23/76 (30%), Positives = 27/76 (35%), Gaps = 10/76 (13%)
Query: 49 CCRVHTTRCCRDYPGEECCSEWDC--MCVQPEFHCGDPCC-TTCRHHPC--PPGQGVQSQ 103
CC CC+ CC C C QP C CC +C PC P G
Sbjct: 42 CC---VPSCCQPCCHPTCCQNTCCRTTCCQPT--CVASCCQPSCCSTPCCQPTCCGSSCC 96
Query: 104 GKFSFGFQCIDCASGT 119
G+ S G C G+
Sbjct: 97 GQTSCGSSCCQPICGS 112
>gi|239751312 PREDICTED: hypothetical protein [Homo sapiens]
Length = 188
Score = 37.0 bits (84), Expect = 0.015
Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 7/53 (13%)
Query: 47 ARCCRVH--TTRCCRDYP-GEECCSEWDC--MCVQPEFHCGDPCCTTCRHHPC 94
A CC+ +T CC+ G CC + C C QP CG CC C H C
Sbjct: 73 ASCCQPSCCSTPCCQPTCCGSSCCGQTSCGSSCCQPI--CGSSCCQPCCHPTC 123
Score = 28.1 bits (61), Expect = 7.1
Identities = 23/76 (30%), Positives = 27/76 (35%), Gaps = 10/76 (13%)
Query: 49 CCRVHTTRCCRDYPGEECCSEWDC--MCVQPEFHCGDPCC-TTCRHHPC--PPGQGVQSQ 103
CC CC+ CC C C QP C CC +C PC P G
Sbjct: 42 CC---VPSCCQPCCHPTCCQNTCCRTTCCQPT--CVASCCQPSCCSTPCCQPTCCGSSCC 96
Query: 104 GKFSFGFQCIDCASGT 119
G+ S G C G+
Sbjct: 97 GQTSCGSSCCQPICGS 112
>gi|239745809 PREDICTED: hypothetical protein [Homo sapiens]
Length = 188
Score = 37.0 bits (84), Expect = 0.015
Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 7/53 (13%)
Query: 47 ARCCRVH--TTRCCRDYP-GEECCSEWDC--MCVQPEFHCGDPCCTTCRHHPC 94
A CC+ +T CC+ G CC + C C QP CG CC C H C
Sbjct: 73 ASCCQPSCCSTPCCQPTCCGSSCCGQTSCGSSCCQPI--CGSSCCQPCCHPTC 123
Score = 28.1 bits (61), Expect = 7.1
Identities = 23/76 (30%), Positives = 27/76 (35%), Gaps = 10/76 (13%)
Query: 49 CCRVHTTRCCRDYPGEECCSEWDC--MCVQPEFHCGDPCC-TTCRHHPC--PPGQGVQSQ 103
CC CC+ CC C C QP C CC +C PC P G
Sbjct: 42 CC---VPSCCQPCCHPTCCQNTCCRTTCCQPT--CVASCCQPSCCSTPCCQPTCCGSSCC 96
Query: 104 GKFSFGFQCIDCASGT 119
G+ S G C G+
Sbjct: 97 GQTSCGSSCCQPICGS 112
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 35.8 bits (81), Expect = 0.034
Identities = 32/94 (34%), Positives = 37/94 (39%), Gaps = 29/94 (30%)
Query: 50 CRVHTTRC--CRDYPGEECCSEWDCMCVQPEFHCGDPCCT---TCRHHPCPPGQGVQ--- 101
C HT C CRD+ G E C C+ FH GDP CR PCP G G Q
Sbjct: 886 CNTHTGACLGCRDHTGGEHCER----CIAG-FH-GDPRLPYGGQCRPCPCPEGPGSQRHF 939
Query: 102 ----SQGKFS-----------FGFQCIDCASGTF 120
Q ++S G +C CA G F
Sbjct: 940 ATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHF 973
>gi|54400749 keratin associated protein 5-1 [Homo sapiens]
Length = 278
Score = 35.8 bits (81), Expect = 0.034
Identities = 27/95 (28%), Positives = 32/95 (33%), Gaps = 5/95 (5%)
Query: 5 GAMGAFRALCGLALLCALSLGQ--RPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYP 62
G+ G + CG C G GG G G G G G CC + C
Sbjct: 168 GSCGGSKGGCGSCGGCKGGCGSCGGSKGGCGSGCGGCGSGCGVPVCCCSCSSCGSCAGSK 227
Query: 63 GEECCSEWDCMCVQP---EFHCGDPCCTTCRHHPC 94
G S C C +P CG CC + PC
Sbjct: 228 GGCGSSCSQCSCCKPCCCSSGCGSSCCQSSCCKPC 262
Score = 31.2 bits (69), Expect = 0.84
Identities = 34/118 (28%), Positives = 39/118 (33%), Gaps = 25/118 (21%)
Query: 14 CGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWDCM 73
CG + C S G +G GCG G G+G C + CC CC
Sbjct: 4 CGCSGGCGSSCGGCGSGCGGCGSGCGGCGSG-----CGGSGSSCCVPV----CC------ 48
Query: 74 CVQPEFHCGDPCC--TTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFS-GGHEGHC 128
C CC TC C G S G C C G S GG +G C
Sbjct: 49 -------CKPVCCRVPTCSCSSCGKGGCGSSGGSKGGCGSCGGCKGGCGSCGGSKGGC 99
Score = 30.4 bits (67), Expect = 1.4
Identities = 20/79 (25%), Positives = 27/79 (34%), Gaps = 11/79 (13%)
Query: 14 CGLALLCAL--SLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWD 71
CG+ + C S G GCG + + CC+ CC G CC
Sbjct: 208 CGVPVCCCSCSSCGSCAGSKGGCG------SSCSQCSCCK---PCCCSSGCGSSCCQSSC 258
Query: 72 CMCVQPEFHCGDPCCTTCR 90
C + C P C C+
Sbjct: 259 CKPCCSQSSCCVPVCCQCK 277
>gi|60593038 keratin associated protein 5-4 [Homo sapiens]
Length = 288
Score = 35.4 bits (80), Expect = 0.045
Identities = 22/90 (24%), Positives = 32/90 (35%), Gaps = 9/90 (10%)
Query: 5 GAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYPGE 64
G+ G + C C+ G C P +G + CC+ + CC+ Y
Sbjct: 192 GSCGCSQCSCCKPCCCSSGCGSSCCQSSCCKP--CCSSSGCGSSCCQ---SSCCKPY--- 243
Query: 65 ECCSEWDCMCVQPEFHCGDPCCTTCRHHPC 94
CC C CG CC + +PC
Sbjct: 244 -CCQSSCCKPCCSSSGCGSSCCQSSCCNPC 272
Score = 28.5 bits (62), Expect = 5.5
Identities = 30/115 (26%), Positives = 38/115 (33%), Gaps = 17/115 (14%)
Query: 14 CGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWDCM 73
CG + C G +G GCG G G G+ C C CC + C
Sbjct: 4 CGCSGGCGSGCGGCGSGCGGCGSG--CGGCGSGCGGCGSGCGGCGSSCCVPICCCKPVCC 61
Query: 74 CVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHC 128
CV P C+ C +G S G C+ C GG +G C
Sbjct: 62 CV--------PACSCSSCGSCGGSKGGYGSCGGSKG-GCVSC------GGSKGGC 101
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 35.0 bits (79), Expect = 0.058
Identities = 43/152 (28%), Positives = 52/152 (34%), Gaps = 33/152 (21%)
Query: 20 CALSLGQR-PTGGPGCGPGRLLLGTGTDARC--CRVHTTRCCRDYPGE-ECCSEW---DC 72
C + G R P+ C PGR RC C+ C G C + W DC
Sbjct: 595 CVCAPGFRGPSCQRSCQPGRY------GKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDC 648
Query: 73 MCVQPEFHCGDPCCTTCRHH---PCPPGQGVQSQGKFSFGFQCID-CASGTFSGGHEGHC 128
P H G+ C TC+ H C P G G C++ C GTF +C
Sbjct: 649 SQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFG----ANC 704
Query: 129 KPWTDCTQFGFLTVFPGNKTH----NAVCVPG 156
C PG K H VC PG
Sbjct: 705 SQPCQCG--------PGEKCHPETGACVCPPG 728
>gi|23200041 tumor necrosis factor receptor superfamily, member 14
precursor [Homo sapiens]
Length = 283
Score = 35.0 bits (79), Expect = 0.058
Identities = 30/110 (27%), Positives = 39/110 (35%), Gaps = 9/110 (8%)
Query: 34 CGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWD---CMCVQPEFHC----GDPCC 86
C PG + ++C + CS + C C P C GD C
Sbjct: 78 CPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVCGC-SPGHFCIVQDGDHCA 136
Query: 87 TTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFS-GGHEGHCKPWTDCT 135
+ PGQ VQ G S C +C GTFS G C+ T C+
Sbjct: 137 ACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSPNGTLEECQHQTKCS 186
Score = 29.3 bits (64), Expect = 3.2
Identities = 20/61 (32%), Positives = 25/61 (40%), Gaps = 12/61 (19%)
Query: 60 DYP-GEECCSEWDCMCVQPEFH----CGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCID 114
+YP G ECC + P + CG+ T C PCPPG + S QC
Sbjct: 46 EYPVGSECCPK-----CSPGYRVKEACGELTGTVCE--PCPPGTYIAHLNGLSKCLQCQM 98
Query: 115 C 115
C
Sbjct: 99 C 99
>gi|29725609 epidermal growth factor receptor isoform a precursor
[Homo sapiens]
Length = 1210
Score = 34.3 bits (77), Expect = 0.099
Identities = 22/96 (22%), Positives = 35/96 (36%), Gaps = 5/96 (5%)
Query: 38 RLLLGTGTDARCCRVHTTRCCRDYPGEECCS--EWDCMCVQP---EFHCGDPCCTTCRHH 92
+++ RC + CC + C E DC+ + E C D C ++
Sbjct: 212 KIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYN 271
Query: 93 PCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHC 128
P V +GK+SFG C+ + G C
Sbjct: 272 PTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSC 307
>gi|41327736 epidermal growth factor receptor isoform d precursor
[Homo sapiens]
Length = 705
Score = 34.3 bits (77), Expect = 0.099
Identities = 22/96 (22%), Positives = 35/96 (36%), Gaps = 5/96 (5%)
Query: 38 RLLLGTGTDARCCRVHTTRCCRDYPGEECCS--EWDCMCVQP---EFHCGDPCCTTCRHH 92
+++ RC + CC + C E DC+ + E C D C ++
Sbjct: 212 KIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYN 271
Query: 93 PCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHC 128
P V +GK+SFG C+ + G C
Sbjct: 272 PTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSC 307
>gi|41327734 epidermal growth factor receptor isoform c precursor
[Homo sapiens]
Length = 405
Score = 34.3 bits (77), Expect = 0.099
Identities = 22/96 (22%), Positives = 35/96 (36%), Gaps = 5/96 (5%)
Query: 38 RLLLGTGTDARCCRVHTTRCCRDYPGEECCS--EWDCMCVQP---EFHCGDPCCTTCRHH 92
+++ RC + CC + C E DC+ + E C D C ++
Sbjct: 212 KIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYN 271
Query: 93 PCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHC 128
P V +GK+SFG C+ + G C
Sbjct: 272 PTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSC 307
>gi|41327732 epidermal growth factor receptor isoform b precursor
[Homo sapiens]
Length = 628
Score = 34.3 bits (77), Expect = 0.099
Identities = 22/96 (22%), Positives = 35/96 (36%), Gaps = 5/96 (5%)
Query: 38 RLLLGTGTDARCCRVHTTRCCRDYPGEECCS--EWDCMCVQP---EFHCGDPCCTTCRHH 92
+++ RC + CC + C E DC+ + E C D C ++
Sbjct: 212 KIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYN 271
Query: 93 PCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHC 128
P V +GK+SFG C+ + G C
Sbjct: 272 PTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSC 307
>gi|65301164 very low density lipoprotein receptor isoform b [Homo
sapiens]
Length = 845
Score = 33.9 bits (76), Expect = 0.13
Identities = 32/109 (29%), Positives = 38/109 (34%), Gaps = 11/109 (10%)
Query: 30 GGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYP-----GEECCSEWDCMCVQPEFHCGDP 84
G P C G R CR+H C C E DC + E +CG+
Sbjct: 93 GDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEENCGNI 152
Query: 85 CCT----TCRHHPCPPGQGV-QSQGKFSFGFQCIDCASGTFSGGHEGHC 128
C+ TC C V Q S G +DCA T G HE C
Sbjct: 153 TCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPT-CGAHEFQC 200
>gi|65301167 very low density lipoprotein receptor isoform a [Homo
sapiens]
Length = 873
Score = 33.9 bits (76), Expect = 0.13
Identities = 32/109 (29%), Positives = 38/109 (34%), Gaps = 11/109 (10%)
Query: 30 GGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYP-----GEECCSEWDCMCVQPEFHCGDP 84
G P C G R CR+H C C E DC + E +CG+
Sbjct: 93 GDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIPVSWRCDGENDCDSGEDEENCGNI 152
Query: 85 CCT----TCRHHPCPPGQGV-QSQGKFSFGFQCIDCASGTFSGGHEGHC 128
C+ TC C V Q S G +DCA T G HE C
Sbjct: 153 TCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPT-CGAHEFQC 200
>gi|11641231 ectodysplasin A receptor precursor [Homo sapiens]
Length = 448
Score = 33.9 bits (76), Expect = 0.13
Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 7/79 (8%)
Query: 87 TTCRHHPCPP-GQGVQSQGKFSFG-----FQCIDCASGTFSGGHEGHCKPWTDCTQFGFL 140
TT CPP G G + +G + C+ C + FS G C+ DC F
Sbjct: 40 TTGLCQECPPCGPGEEPYLSCGYGTKDEDYGCVPCPAEKFSKGGYQICRRHKDCEGFFRA 99
Query: 141 TVF-PGNKTHNAVCVPGSP 158
TV PG+ ++A C P P
Sbjct: 100 TVLTPGDMENDAECGPCLP 118
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.140 0.504
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,997,180
Number of Sequences: 37866
Number of extensions: 740001
Number of successful extensions: 3047
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 125
Number of HSP's that attempted gapping in prelim test: 2862
Number of HSP's gapped (non-prelim): 292
length of query: 241
length of database: 18,247,518
effective HSP length: 99
effective length of query: 142
effective length of database: 14,498,784
effective search space: 2058827328
effective search space used: 2058827328
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.