Search of human proteins with 4759112

Search of human proteins with 4759112

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4759112 solute carrier family 16, member 3 [Homo sapiens]
         (465 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|109288010 solute carrier family 16, member 3 [Homo sapiens]        928   0.0  
gi|109288012 solute carrier family 16, member 3 [Homo sapiens]        928   0.0  
gi|4759112 solute carrier family 16, member 3 [Homo sapiens]          928   0.0  
gi|114796626 solute carrier family 16, member 8 [Homo sapiens]        517   e-146
gi|24431958 solute carrier family 16, member 7 [Homo sapiens]         411   e-115
gi|115583685 solute carrier family 16, member 1 [Homo sapiens]        380   e-105
gi|4759116 solute carrier family 16, member 5 [Homo sapiens]          318   7e-87
gi|169217968 PREDICTED: similar to solute carrier family 16, mem...   264   1e-70
gi|23503293 solute carrier family 16, member 11 [Homo sapiens]        249   3e-66
gi|157041233 solute carrier family 16 (monocarboxylic acid trans...   249   4e-66
gi|42475555 monocarboxylate transporter 13 [Homo sapiens]             236   4e-62
gi|40789261 solute carrier family 16, member 6 [Homo sapiens]         218   7e-57
gi|18699730 solute carrier family 16, member 10 [Homo sapiens]        181   1e-45
gi|5730045 solute carrier family 16, member 2 [Homo sapiens]          177   2e-44
gi|34916028 solute carrier family 16 (monocarboxylic acid transp...   143   4e-34
gi|41327156 solute carrier family 16 (monocarboxylic acid transp...   140   2e-33
gi|4759114 solute carrier family 16, member 4 [Homo sapiens]          108   1e-23
gi|215272390 solute carrier family 18 (vesicular monoamine), mem...    39   0.008
gi|215272392 solute carrier family 18 (vesicular monoamine), mem...    38   0.022
gi|208879454 solute carrier family 18 (vesicular monoamine), mem...    38   0.022
gi|4506987 solute carrier family 18 (vesicular monoamine), membe...    38   0.022
gi|42476325 solute carrier family 18 (vesicular monoamine), memb...    35   0.11 
gi|16445357 hypothetical protein LOC116843 [Homo sapiens]              32   1.6  
gi|34330168 olfactory receptor, family 6, subfamily A, member 2 ...    31   2.1  
gi|167614500 lymphocyte-activation protein 3 precursor [Homo sap...    31   2.7  
gi|38569457 solute carrier family 12, member 8 [Homo sapiens]          30   3.6  
gi|166064062 tumor suppressing subtransferable candidate 5 [Homo...    30   4.7  
gi|166064060 tumor suppressing subtransferable candidate 5 [Homo...    30   4.7  
gi|187608446 phosphatidylinositol glycan anchor biosynthesis, cl...    30   4.7  
gi|187608438 phosphatidylinositol glycan anchor biosynthesis, cl...    30   4.7  

>gi|109288010 solute carrier family 16, member 3 [Homo sapiens]
          Length = 465

 Score =  928 bits (2399), Expect = 0.0
 Identities = 465/465 (100%), Positives = 465/465 (100%)

Query: 1   MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDT 60
           MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDT
Sbjct: 1   MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDT 60

Query: 61  AWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGV 120
           AWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGV
Sbjct: 61  AWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGV 120

Query: 121 ITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGF 180
           ITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGF
Sbjct: 121 ITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGF 180

Query: 181 LILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVL 240
           LILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVL
Sbjct: 181 LILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVL 240

Query: 241 GLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSF 300
           GLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSF
Sbjct: 241 GLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSF 300

Query: 301 SMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVL 360
           SMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVL
Sbjct: 301 SMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVL 360

Query: 361 LMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPE 420
           LMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPE
Sbjct: 361 LMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPE 420

Query: 421 VAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV 465
           VAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV
Sbjct: 421 VAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV 465


>gi|109288012 solute carrier family 16, member 3 [Homo sapiens]
          Length = 465

 Score =  928 bits (2399), Expect = 0.0
 Identities = 465/465 (100%), Positives = 465/465 (100%)

Query: 1   MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDT 60
           MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDT
Sbjct: 1   MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDT 60

Query: 61  AWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGV 120
           AWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGV
Sbjct: 61  AWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGV 120

Query: 121 ITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGF 180
           ITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGF
Sbjct: 121 ITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGF 180

Query: 181 LILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVL 240
           LILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVL
Sbjct: 181 LILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVL 240

Query: 241 GLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSF 300
           GLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSF
Sbjct: 241 GLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSF 300

Query: 301 SMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVL 360
           SMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVL
Sbjct: 301 SMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVL 360

Query: 361 LMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPE 420
           LMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPE
Sbjct: 361 LMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPE 420

Query: 421 VAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV 465
           VAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV
Sbjct: 421 VAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV 465


>gi|4759112 solute carrier family 16, member 3 [Homo sapiens]
          Length = 465

 Score =  928 bits (2399), Expect = 0.0
 Identities = 465/465 (100%), Positives = 465/465 (100%)

Query: 1   MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDT 60
           MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDT
Sbjct: 1   MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDT 60

Query: 61  AWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGV 120
           AWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGV
Sbjct: 61  AWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGV 120

Query: 121 ITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGF 180
           ITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGF
Sbjct: 121 ITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGF 180

Query: 181 LILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVL 240
           LILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVL
Sbjct: 181 LILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVL 240

Query: 241 GLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSF 300
           GLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSF
Sbjct: 241 GLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSF 300

Query: 301 SMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVL 360
           SMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVL
Sbjct: 301 SMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVL 360

Query: 361 LMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPE 420
           LMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPE
Sbjct: 361 LMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPE 420

Query: 421 VAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV 465
           VAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV
Sbjct: 421 VAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV 465


>gi|114796626 solute carrier family 16, member 8 [Homo sapiens]
          Length = 504

 Score =  517 bits (1331), Expect = e-146
 Identities = 265/462 (57%), Positives = 322/462 (69%), Gaps = 46/462 (9%)

Query: 2   GGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTA 61
           GG    EGP     PDGGWGW VL  CFV+TGF+Y FPKAVSVFF+ L+++F  GYSDTA
Sbjct: 4   GGPRRGEGP-----PDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTA 58

Query: 62  WISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVI 121
           W+SSI+LAMLYGTGP+ S+ V RFGCRPVML GGL AS GM+ ASF   ++++YLT GV+
Sbjct: 59  WVSSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVL 118

Query: 122 TGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFL 181
           TGLGLALNFQPSLIML  YF +RRP+ANGLAAAGSPVFL ALSPLGQ L +R+GWRGGFL
Sbjct: 119 TGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFL 178

Query: 182 ILGGLLLNCCVCAALMRPLVVTAQPGSGP------------------------------- 210
           +LGGLLL+CC C A+MRP      PG GP                               
Sbjct: 179 LLGGLLLHCCACGAVMRP-----PPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREAS 233

Query: 211 --PRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLT 268
              RP RRLLDL+V  DR F +YAV   +M LGLFVP + +V+YAKD GVPDT AAFLL+
Sbjct: 234 PRVRPRRRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLS 293

Query: 269 ILGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFF 328
           I+GF+DI ARPA G +AGL ++RP+  YLFS ++  NGL DL+ + A  YG LV FC+ F
Sbjct: 294 IVGFVDIVARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAF 353

Query: 329 GISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVF 388
           G+SYGMVGALQFEVLMA VG  +F SA+GLVLL+EA AVL+GPPS G+L+D    Y  +F
Sbjct: 354 GLSYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIF 413

Query: 389 ILAGAEVLTSSLILLLGNFFCIR---KKPKEPQPEVAAAEEE 427
            LAG+EV  + + + +    C+R     P  P  E  A++ E
Sbjct: 414 YLAGSEVALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTE 455


>gi|24431958 solute carrier family 16, member 7 [Homo sapiens]
          Length = 478

 Score =  411 bits (1056), Expect = e-115
 Identities = 210/450 (46%), Positives = 288/450 (64%), Gaps = 24/450 (5%)

Query: 16  PDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYGTG 75
           PDGGWGW V+   F+  GFSYAFPKAV+VFFKE+ Q F   YS+ AWISSI+LA++Y  G
Sbjct: 14  PDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAGG 73

Query: 76  PLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLI 135
           P+ SV VN++G RPV++ GGL   LGMV ASF  S++Q+YLT G ITGLGLA N QP+L 
Sbjct: 74  PVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALT 133

Query: 136 MLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAA 195
           ++ +YF ++RPMANGLA AGSPVFL +L+P  Q L + +GW+G FLILG LLLN CV  +
Sbjct: 134 IIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGS 193

Query: 196 LMRPL------------VVTAQPGSGPPR---------PSRRLLDLSVFRDRGFVLYAVA 234
           LMRPL                +  S P +            + LD S+F+ RGF++Y   
Sbjct: 194 LMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLIYLSG 253

Query: 235 ASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYS 294
             +M LG F P +F+  YAKD G+ +  AAFLL+++ F+D+FARP+ G +A    +RP  
Sbjct: 254 NVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRI 313

Query: 295 VYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSS 354
            Y FSF++ FNG+  L    A DY  LV++ +FFG+ +G V ++ FE LM +VG  +FSS
Sbjct: 314 QYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSS 373

Query: 355 AIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLG---NFFCIR 411
           A+GLV ++E   VL+GPP  GKL+D T  Y Y+++  GA V+ +S+ LL+G   N+  + 
Sbjct: 374 AVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLA 433

Query: 412 KKPKEPQPEVAAAEEEKLHKPPADSGVDLR 441
           K+ KE        E E L K      V+++
Sbjct: 434 KERKEENARQKTRESEPLSKSKHSEDVNVK 463


>gi|115583685 solute carrier family 16, member 1 [Homo sapiens]
          Length = 500

 Score =  380 bits (976), Expect = e-105
 Identities = 201/459 (43%), Positives = 274/459 (59%), Gaps = 40/459 (8%)

Query: 9   GPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILL 68
           GP G   PDGGWGWAV+ G F+  GFSYAFPK+++VFFKE+   F    S+ +WISSI+L
Sbjct: 7   GPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIML 66

Query: 69  AMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLAL 128
           A++YG GP+ S+ VN++G R VM+VGG  +  G++AASFC ++ Q+Y+  GVI GLGLA 
Sbjct: 67  AVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAF 126

Query: 129 NFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLL 188
           N  P+L M+ +YF KRRP+ANGLA AGSPVFLC L+PL Q+    +GWRG FLILGGLLL
Sbjct: 127 NLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLL 186

Query: 189 NCCVCAALMRPL------------------------------VVTAQPGSGPPRPSR--- 215
           NCCV  ALMRP+                                T   G  P +  R   
Sbjct: 187 NCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVF 246

Query: 216 ----RLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILG 271
               + LDL++F  RGF+LY     +M  GLF P VF+ SY K       K+AFLL+IL 
Sbjct: 247 QTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILA 306

Query: 272 FIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGIS 331
           F+D+ ARP+ G VA    +RP   Y F+ S+  NG+  +    +  Y G  V+  FFG +
Sbjct: 307 FVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFA 366

Query: 332 YGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILA 391
           +G + ++ FE LM +VG  +FSSA+GLV ++E   VL+GPP  G+L D    Y Y +   
Sbjct: 367 FGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWAC 426

Query: 392 GAEVLTSSLILLLG---NFFCIRKKPKEPQPEVAAAEEE 427
           G  ++ S + L +G   N+  + K+ K  + +  + EEE
Sbjct: 427 GVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEE 465


>gi|4759116 solute carrier family 16, member 5 [Homo sapiens]
          Length = 505

 Score =  318 bits (815), Expect = 7e-87
 Identities = 170/438 (38%), Positives = 256/438 (58%), Gaps = 19/438 (4%)

Query: 10  PTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLA 69
           P  ++  DG W W VL    V  G +  FP  + +FF EL  EF    S+T+W  SIL A
Sbjct: 2   PQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILTA 61

Query: 70  MLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALN 129
           +L+  GPLCS+ V RFGCR  +++GG+ ASLGMVA+SF  ++ Q+Y T G ITGLG+  +
Sbjct: 62  VLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFS 121

Query: 130 FQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLN 189
           FQ S+ +L  YF +RR +AN LA+ G  + +     L + L +  GWRG FL+ GG+ L+
Sbjct: 122 FQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLH 181

Query: 190 CCVCAALMRPLVVTAQPGS---GPPRPS--------------RRLLDLSVFR-DRGFVLY 231
           CC+C A++RP+  +  P +    PP P               +R L   + R + G+ +Y
Sbjct: 182 CCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVY 241

Query: 232 AVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVR 291
            +     VLG  +P VF+V YA    V + +AA L++I+GF +IF RP AG +AG     
Sbjct: 242 ILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFA 301

Query: 292 PYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHK 351
            +  YLFS ++  NGL +L  + +GD+  LV +C+ + +S   +GAL F+VLM IV   +
Sbjct: 302 SHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQ 361

Query: 352 FSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIR 411
           F  A+GL  +++ +A L+ PP  G LLDAT+ + YVF ++ +  L S+ + + G+F+ ++
Sbjct: 362 FPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMS-SFFLISAALFMGGSFYALQ 420

Query: 412 KKPKEPQPEVAAAEEEKL 429
           KK +  Q   A A E  L
Sbjct: 421 KKEQGKQAVAADALERDL 438


>gi|169217968 PREDICTED: similar to solute carrier family 16, member
           5 [Homo sapiens]
          Length = 453

 Score =  264 bits (674), Expect = 1e-70
 Identities = 144/372 (38%), Positives = 221/372 (59%), Gaps = 19/372 (5%)

Query: 76  PLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLI 135
           PLCS+ V RFGCR  +++GG+ ASLGMVA+SF  ++ Q+Y T G ITGLG+  +FQ S+ 
Sbjct: 16  PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75

Query: 136 MLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAA 195
           +L  YF +RR +AN LA+ G  + +     L + L +  GWRG FL+ GG+ L+CC+C A
Sbjct: 76  VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135

Query: 196 LMRPLVVTAQPGS---GPPRPS--------------RRLLDLSVFR-DRGFVLYAVAASV 237
           ++RP+  +  P +    PP P               +R L   + R + G+ +Y +    
Sbjct: 136 IIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMW 195

Query: 238 MVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYL 297
            VLG  +P VF+V YA    V + +AA L++I+GF +IF RP AG +AG      +  YL
Sbjct: 196 SVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYL 255

Query: 298 FSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIG 357
           FS ++  NGL +L  + +GD+  LV +C+ + +S   +GAL F+VLM IV   +F  A+G
Sbjct: 256 FSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALG 315

Query: 358 LVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEP 417
           L  +++ +A L+ PP  G LLDAT+ + YVF ++ +  L S+ + + G+F+ ++KK +  
Sbjct: 316 LFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMS-SFFLISAALFMGGSFYALQKKEQGK 374

Query: 418 QPEVAAAEEEKL 429
           Q   A A E  L
Sbjct: 375 QAVAADALERDL 386


>gi|23503293 solute carrier family 16, member 11 [Homo sapiens]
          Length = 471

 Score =  249 bits (637), Expect = 3e-66
 Identities = 146/399 (36%), Positives = 217/399 (54%), Gaps = 6/399 (1%)

Query: 10  PTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLA 69
           P     PDGGWGW V    F I G SY   +++ + F +L + F     DTAWIS++ LA
Sbjct: 27  PQPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALA 86

Query: 70  MLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALN 129
           +     P+ S    R+G RPV++VGG+ ASLG V ++F   ++ +YL  G++ G G AL 
Sbjct: 87  VQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALV 146

Query: 130 FQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLN 189
           F P+L  L+RYFS+RR +A GLA  G+      L+P  QLL D +GWRG  L+LG + L+
Sbjct: 147 FAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLH 206

Query: 190 CCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFV 249
              C AL+ PLV+   P   PPR     L LS+F  R F ++A+  +++  G FVP V +
Sbjct: 207 LTPCGALLLPLVLPGDP-PAPPRSPLAALGLSLFTRRAFSIFALGTALVGGGYFVPYVHL 265

Query: 250 VSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKV---RPYSVY--LFSFSMFF 304
             +A D G+    AA ++ +    D  AR   G++A  G V   R  +V+  L    ++ 
Sbjct: 266 APHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLGLWV 325

Query: 305 NGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEA 364
            GL  + G      G L+   + +G+S G    L F VL  +VG      A GLV+++ +
Sbjct: 326 VGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLVMMLMS 385

Query: 365 VAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILL 403
           +  L+GPP  G L D T  +   F+L+G+ +L+ S I +
Sbjct: 386 LGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGSFIYI 424


>gi|157041233 solute carrier family 16 (monocarboxylic acid
           transporters), member 12 [Homo sapiens]
          Length = 486

 Score =  249 bits (636), Expect = 4e-66
 Identities = 155/440 (35%), Positives = 229/440 (52%), Gaps = 31/440 (7%)

Query: 16  PDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYGTG 75
           PDGGWGW ++ GCF++T  + A  + +S+FF E    F   Y+ TAWI SI+  +     
Sbjct: 13  PDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTMLCA 72

Query: 76  PLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLI 135
           PL SV  N   C+  +++GGL AS G++ +SF  S+  +YLT GV+TGLG AL + P++ 
Sbjct: 73  PLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAIA 132

Query: 136 MLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAA 195
           M+ +YFS+R+ +A G+A +GS +    L+P+ QLL +++ WRG  LILGG +LN CVC A
Sbjct: 133 MVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGA 192

Query: 196 LMRPLVV--------------TAQPGSGPPRPSRRLL--------------DLSVFRDRG 227
           LMRP+ +              T +       P   L               + S      
Sbjct: 193 LMRPITLKEDHTTPEQNHVCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMSD 252

Query: 228 FVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGL 287
           FV+ AV+   M  G     V++V YA  +GV   +AAFL++ILG IDI      G++   
Sbjct: 253 FVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTDR 312

Query: 288 GKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIV 347
             ++ Y    + F++  +GL  L          LV F   FG   G    L   V   IV
Sbjct: 313 RCLKNYQYVCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEIV 372

Query: 348 GTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNF 407
           GT   SSA+G+V  + AV  LV PP  G+L+D T  Y   F+L G  ++ SS++L    F
Sbjct: 373 GTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLL---GF 429

Query: 408 FCIRKKPKEPQPEVAAAEEE 427
             + K+ ++ Q +  A E +
Sbjct: 430 ARLIKRMRKTQLQFIAKESD 449


>gi|42475555 monocarboxylate transporter 13 [Homo sapiens]
          Length = 426

 Score =  236 bits (601), Expect = 4e-62
 Identities = 143/419 (34%), Positives = 218/419 (52%), Gaps = 9/419 (2%)

Query: 16  PDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYGTG 75
           PDGGWGW V+   F  +   +   ++  VFF E +  F    +  +WI+SI +A+     
Sbjct: 8   PDGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGS 67

Query: 76  PLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLI 135
           P+ S    +FG RPV++ GG+ A+LGM+ ASF  S+  +YL+ G+++G G AL F P+L 
Sbjct: 68  PVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFAPTLA 127

Query: 136 MLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAA 195
            L+ YFS+RR +A GLA  G  +     +P  Q L   Y WRG  L++  L L+   C A
Sbjct: 128 CLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACGA 187

Query: 196 LMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKD 255
           L+RP  +   P  G PR        S+     F+ Y VA +++  G F+P + +V++ +D
Sbjct: 188 LLRPPSLAEDPAVGGPRAQL----TSLLHHGPFLRYTVALTLINTGYFIPYLHLVAHLQD 243

Query: 256 LGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSV-YLFSFSMFFNGLADLAGST 314
           L      AAFLL+++   D+  R  +G+   LG   P  V  L        G++      
Sbjct: 244 LDWDPLPAAFLLSVVAISDLVGRVVSGW---LGDAVPGPVTRLLMLWTTLTGVSLALFPV 300

Query: 315 AGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSG 374
           A     LV   + +G + G +  L F VL  ++GT +    +GL+ ++E++  L+GPP  
Sbjct: 301 AQAPTALVALAVAYGFTSGALAPLAFSVLPELIGTRRIYCGLGLLQMIESIGGLLGPPLS 360

Query: 375 GKLLDATHVYMYVFILAGAEVLTSSLILL-LGNFFCIRKKPKEPQPEVAAAEEEKLHKP 432
           G L D T  Y   F++AGA +L+ S ILL L +FFC       PQ  V  A + K+  P
Sbjct: 361 GYLRDVTGNYTASFVVAGAFLLSGSGILLTLPHFFCFSTTTSGPQDLVTEALDTKVPLP 419


>gi|40789261 solute carrier family 16, member 6 [Homo sapiens]
          Length = 523

 Score =  218 bits (556), Expect = 7e-57
 Identities = 137/456 (30%), Positives = 216/456 (47%), Gaps = 67/456 (14%)

Query: 14  KAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYG 73
           + PDGGWGWAV    F +  F+Y   K   VFF +L+  F    S  +WI SI + +L  
Sbjct: 17  EVPDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVLTF 76

Query: 74  TGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPS 133
           + PL +V  NRFG R V+++GGL  S GMVAASF + +  +Y+  G+I+GLG   +F P+
Sbjct: 77  SAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPT 136

Query: 134 LIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFL---------ILG 184
           + +L++YF KRR +   +A+ G    + A +P    L++R GWR   L         ++ 
Sbjct: 137 VTILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIF 196

Query: 185 GLLLNCCVCAALMRPLVV------------------------------TAQPGSGP---- 210
           G LL          P +V                              T  P + P    
Sbjct: 197 GALLRPIFIRGPASPKIVIQENRKEAQYMLENEKTRTSIDSIDSGVELTTSPKNVPTHTN 256

Query: 211 -----------------PRPSRR---LLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVV 250
                            PRPS +   LLD S+ +++ F+ YA+      LG F P ++++
Sbjct: 257 LELEPKADMQQVLVKTSPRPSEKKAPLLDFSILKEKSFICYALFGLFATLGFFAPSLYII 316

Query: 251 SYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADL 310
                LG+   +AAFLL+ +   ++F R  AGFV     +R   +Y+    +    ++  
Sbjct: 317 PLGISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVLNREPIR--KIYIELICVILLTVSLF 374

Query: 311 AGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMA--IVGTHKFSSAIGLVLLMEAVAVL 368
           A + A ++ GL+   IFFG   G +G     +L    +VG  K SSA G+ + ++++A L
Sbjct: 375 AFTFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGL 434

Query: 369 VGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLL 404
            GPP  G L+D + +Y   F    A +  +++ L L
Sbjct: 435 AGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLAL 470



 Score = 33.5 bits (75), Expect = 0.42
 Identities = 26/116 (22%), Positives = 52/116 (44%), Gaps = 13/116 (11%)

Query: 299 SFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGL 358
           +F +FFN L D    +      ++  C+F          L F   +A V +++F     L
Sbjct: 44  TFGVFFNDLMDSFNESNSRISWIISICVF---------VLTFSAPLATVLSNRFGHR--L 92

Query: 359 VLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSL--ILLLGNFFCIRK 412
           V+++  + V  G  +     + +H+Y+ + I++G     S L  + +L  +F  R+
Sbjct: 93  VVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVTILSQYFGKRR 148


>gi|18699730 solute carrier family 16, member 10 [Homo sapiens]
          Length = 515

 Score =  181 bits (460), Expect = 1e-45
 Identities = 120/423 (28%), Positives = 192/423 (45%), Gaps = 27/423 (6%)

Query: 1   MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSD- 59
           + G    E     + P+GGWGW V+       G  +    A  V F  +++ FG    D 
Sbjct: 50  LAGPATAEPHEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDK 109

Query: 60  ----TAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVY 115
               TAW+ S+ + M++   P+ SV  + FGCR   +VG     +G++++SF  SI  +Y
Sbjct: 110 MVFKTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLY 169

Query: 116 LTTGVITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYG 175
           LT G+I   G +  +QPSL++L  YF KR  + NG+  AGS VF   L  L ++L D  G
Sbjct: 170 LTYGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVG 229

Query: 176 WRGGFLILGGLLLNCCVCAALMRPLVVTAQP----GSGPP-------RPSRRLLDLSVFR 224
                 +L   +    +     RPL  + +     GSG          P +++ + ++F+
Sbjct: 230 LFYTLRVLCIFMFVLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFK 289

Query: 225 DRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFID-----IFARP 279
              + ++AV   + + G FVP V ++ +  +    +     +L  +G        +F R 
Sbjct: 290 VTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGR- 348

Query: 280 AAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQ 339
            A +V G+ K     VYL   S FF GL  +       +G L+  C+  G+  G   ++ 
Sbjct: 349 IADYVPGVKK-----VYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIM 403

Query: 340 FEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSS 399
             +   +VG    S AIG +L   ++ + VGPP  G L D    Y   F LAG   L   
Sbjct: 404 APIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGG 463

Query: 400 LIL 402
            +L
Sbjct: 464 AVL 466


>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
          Length = 613

 Score =  177 bits (449), Expect = 2e-44
 Identities = 126/465 (27%), Positives = 209/465 (44%), Gaps = 44/465 (9%)

Query: 12  GVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDT----AWISSIL 67
           G + P+GG+GW V+F      G  +    +V + +  L++E            AW+ ++ 
Sbjct: 165 GFQPPEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALA 224

Query: 68  LAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLA 127
           + M++   P+ S+  +R GCR     G   A +G+  +SF  S+   Y T G++ G G +
Sbjct: 225 MGMIFFCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCS 284

Query: 128 LNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLL 187
             FQPSL++L  YF +R  +ANG+ +AGS +F  +   L ++L D+      F +L   +
Sbjct: 285 FAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVLSTFM 344

Query: 188 LNCCVCAALMRPLVVTAQ--PGSGPPR--------PSRRLLDLSVFRDRGFVLYAVAASV 237
               + +   RPL+ ++Q  P     R          R+  ++ VFR R + ++A   + 
Sbjct: 345 FVLMLLSLTYRPLLPSSQDTPSKRGVRTLHQRFLAQLRKYFNMRVFRQRTYRIWAFGIAA 404

Query: 238 MVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVA----GLGKVRPY 293
             LG FVP V ++ Y ++      +   LL  +G      R  +G ++    GL K    
Sbjct: 405 AALGYFVPYVHLMKYVEEEFSEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKK---- 460

Query: 294 SVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFS 353
            +YL   S    GL  +      D+GGL+V C+F G+  G    +   +   +VG  + S
Sbjct: 461 -IYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQAS 519

Query: 354 SAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKK 413
            AIG +L M A+ ++ GPP  G L +    Y   F  AG   +  ++IL    FF     
Sbjct: 520 QAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVIL----FF----- 570

Query: 414 PKEPQPEVAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVV 458
                  V    +    K   DS  D       L  +P+ NGE++
Sbjct: 571 -------VPLMHQRMFKKEQRDSSKD-----KMLAPDPDPNGELL 603


>gi|34916028 solute carrier family 16 (monocarboxylic acid
           transporters), member 9 [Homo sapiens]
          Length = 509

 Score =  143 bits (360), Expect = 4e-34
 Identities = 75/214 (35%), Positives = 116/214 (54%)

Query: 14  KAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYG 73
           K+PDGGWGW ++F  F+     Y  P AV V + E +  FG G   TAW+ S+   +   
Sbjct: 5   KSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLL 64

Query: 74  TGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPS 133
             P+CS+CV+ FG RPV +  G   + G++ +SF  +I  ++ + G++ GLG  L +  +
Sbjct: 65  ASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTAT 124

Query: 134 LIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVC 193
           + +  +YF  RR +A GL + GS V L   + L ++L + YG  G  LI+G L LN   C
Sbjct: 125 VTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILAC 184

Query: 194 AALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRG 227
            +LMRPL  +  P      P       S++ ++G
Sbjct: 185 GSLMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKG 218



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 50/205 (24%), Positives = 87/205 (42%), Gaps = 9/205 (4%)

Query: 220 LSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAF-LLTILGFIDIFAR 278
           +++F+++ F    +A  +  +G F P + +   A+   V + +    L++I+G +    +
Sbjct: 298 VALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGK 357

Query: 279 PAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGAL 338
              G +A    +   ++YL+  ++   GLA  A   A  Y  L +     G   G     
Sbjct: 358 LLLGILADFKWIN--TLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIF 415

Query: 339 QFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTS 398
            + V    VG  K + A G+++    +   +GPP  G   D T  Y   F  +G  VL  
Sbjct: 416 PY-VTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLG 474

Query: 399 SLILLLGNF----FCIRKKPKEPQP 419
             ILLL        C ++ PK P P
Sbjct: 475 GFILLLAALPSWDTCNKQLPK-PAP 498


>gi|41327156 solute carrier family 16 (monocarboxylic acid
           transporters), member 14 [Homo sapiens]
          Length = 510

 Score =  140 bits (354), Expect = 2e-33
 Identities = 71/200 (35%), Positives = 107/200 (53%), Gaps = 4/200 (2%)

Query: 17  DGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYGTGP 76
           DGGW W ++   F +         A+ V   E ++EF      TAW+SS+ + +    GP
Sbjct: 29  DGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGP 88

Query: 77  LCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLIM 136
              + +N  GCR   ++GGL  SLG V +++  ++  +++T GV  GLG  + + P+++M
Sbjct: 89  FIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMAYLPAVVM 148

Query: 137 LNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAAL 196
           + RYF KRR +A GL+  G+      ++ L + L   YGWR   LI G + LN CVC AL
Sbjct: 149 VGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLNLCVCGAL 208

Query: 197 MRPLVVTAQPGSGPPRPSRR 216
           MRPL     PG  P  P  +
Sbjct: 209 MRPL----SPGKNPNDPGEK 224



 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 49/192 (25%), Positives = 82/192 (42%), Gaps = 6/192 (3%)

Query: 221 SVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLT-ILGFIDIFARP 279
           S+F +R FV +   A        +P + +        + +    F LT I+  + IF + 
Sbjct: 309 SLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFGKV 368

Query: 280 AAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQ 339
             G +A L  +  ++V+L +   F   L+         Y GL V C   G S G    + 
Sbjct: 369 ILGVIADLPCISVWNVFLLA--NFTLVLSIFILPLMHTYAGLAVICALIGFSSGYFSLMP 426

Query: 340 FEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSS 399
             V   +VG    ++A G+++    ++ L+GPP  G + D T  Y + F + G   +   
Sbjct: 427 V-VTEDLVGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIGI 485

Query: 400 LILLLGNFFCIR 411
           L LL+    CIR
Sbjct: 486 LFLLIQP--CIR 495


>gi|4759114 solute carrier family 16, member 4 [Homo sapiens]
          Length = 487

 Score =  108 bits (270), Expect = 1e-23
 Identities = 55/196 (28%), Positives = 101/196 (51%), Gaps = 1/196 (0%)

Query: 14  KAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYG 73
           K  DGGWGW ++   F++  F     K  ++FF    +EF        WI SI+ ++ + 
Sbjct: 13  KTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFC 72

Query: 74  TGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPS 133
            GPL ++  +  G +   ++G    + G + +S+  SI  + +T G++ GLG A  +Q +
Sbjct: 73  AGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVA 132

Query: 134 LIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVC 193
            ++  +YF KR  ++  +A +G  +    L+P  + L D Y W G  ++ G + LN    
Sbjct: 133 AVVTTKYFKKRLALSTAIARSGMGLTF-LLAPFTKFLIDLYDWTGALILFGAIALNLVPS 191

Query: 194 AALMRPLVVTAQPGSG 209
           + L+RP+ + ++  SG
Sbjct: 192 SMLLRPIHIKSENNSG 207



 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 51/186 (27%), Positives = 91/186 (48%), Gaps = 2/186 (1%)

Query: 215 RRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFID 274
           ++L D+S+FR+  F ++  +  +  L  F+P   +V+ AK LG+    A++L+++ G ++
Sbjct: 288 KQLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILE 347

Query: 275 IFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGM 334
             ++  +G+VA    ++ Y  +     +   G+ +L    A  +  L+ + I F I  G 
Sbjct: 348 TVSQIISGWVADQNWIKKY--HYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGG 405

Query: 335 VGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAE 394
             AL   VL+ +      +  +GL      +AVL GPP  G L D T  Y   F  +G  
Sbjct: 406 YLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGIC 465

Query: 395 VLTSSL 400
            L SS+
Sbjct: 466 YLLSSV 471


>gi|215272390 solute carrier family 18 (vesicular monoamine), member
           1 isoform b [Homo sapiens]
          Length = 493

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 76/309 (24%), Positives = 122/309 (39%), Gaps = 39/309 (12%)

Query: 45  FFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVA 104
           F +E I   G+ ++  A +  ++   +   GPL     NR G    M  G +   L  V 
Sbjct: 131 FLEEEITRVGVLFASKAVMQLLVNPFV---GPL----TNRIGYHIPMFAGFVIMFLSTVM 183

Query: 105 ASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSK--RRPMANGLAAAGSPVFLCA 162
            +F  +   +++    + G+G + +    L ML   ++    R  A G A  G  + L  
Sbjct: 184 FAFSGTYTLLFVAR-TLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLV 242

Query: 163 LSPLGQLLQDRYGWRGGFLILGGL-LLNCCVCAALMRPLVVTAQPGSGPP---------- 211
            +P G ++ +  G    FLIL  L LL+  +   +++P  V+ +   G P          
Sbjct: 243 GAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDPYI 302

Query: 212 --RPSRRLLDLSVFRDRGFVLYAVAASVM------VLGLFV--PPVFVVSYAKDL-GVPD 260
                   L  SV    G  L+ V A+ M      ++G+ V    +  V  A ++ G+  
Sbjct: 303 LVAAGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIG 362

Query: 261 TKAAFLLTILGFIDIFARPAAGFVAGLGKVRPY-SVYLFSFSMFFNGLADLAGSTAGDYG 319
             A   L I G +D    P  G +  L     Y SVY  +   F  G A +  ST    G
Sbjct: 363 PNAGLGLAI-GMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFA-IGPST----G 416

Query: 320 GLVVFCIFF 328
           G +V  I F
Sbjct: 417 GAIVKAIGF 425


>gi|215272392 solute carrier family 18 (vesicular monoamine), member
           1 isoform c [Homo sapiens]
          Length = 472

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 41/170 (24%), Positives = 73/170 (42%), Gaps = 11/170 (6%)

Query: 45  FFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVA 104
           F +E I   G+ ++  A +  ++   +   GPL     NR G    M  G +   L  V 
Sbjct: 131 FLEEEITRVGVLFASKAVMQLLVNPFV---GPL----TNRIGYHIPMFAGFVIMFLSTVM 183

Query: 105 ASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSK--RRPMANGLAAAGSPVFLCA 162
            +F  +   +++    + G+G + +    L ML   ++    R  A G A  G  + L  
Sbjct: 184 FAFSGTYTLLFVAR-TLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLV 242

Query: 163 LSPLGQLLQDRYGWRGGFLILGGL-LLNCCVCAALMRPLVVTAQPGSGPP 211
            +P G ++ +  G    FLIL  L LL+  +   +++P  V+ +   G P
Sbjct: 243 GAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTP 292


>gi|208879454 solute carrier family 18 (vesicular monoamine), member
           1 isoform a [Homo sapiens]
          Length = 525

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 41/170 (24%), Positives = 73/170 (42%), Gaps = 11/170 (6%)

Query: 45  FFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVA 104
           F +E I   G+ ++  A +  ++   +   GPL     NR G    M  G +   L  V 
Sbjct: 131 FLEEEITRVGVLFASKAVMQLLVNPFV---GPL----TNRIGYHIPMFAGFVIMFLSTVM 183

Query: 105 ASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSK--RRPMANGLAAAGSPVFLCA 162
            +F  +   +++    + G+G + +    L ML   ++    R  A G A  G  + L  
Sbjct: 184 FAFSGTYTLLFVAR-TLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLV 242

Query: 163 LSPLGQLLQDRYGWRGGFLILGGL-LLNCCVCAALMRPLVVTAQPGSGPP 211
            +P G ++ +  G    FLIL  L LL+  +   +++P  V+ +   G P
Sbjct: 243 GAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTP 292


>gi|4506987 solute carrier family 18 (vesicular monoamine), member 1
           isoform a [Homo sapiens]
          Length = 525

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 41/170 (24%), Positives = 73/170 (42%), Gaps = 11/170 (6%)

Query: 45  FFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVA 104
           F +E I   G+ ++  A +  ++   +   GPL     NR G    M  G +   L  V 
Sbjct: 131 FLEEEITRVGVLFASKAVMQLLVNPFV---GPL----TNRIGYHIPMFAGFVIMFLSTVM 183

Query: 105 ASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSK--RRPMANGLAAAGSPVFLCA 162
            +F  +   +++    + G+G + +    L ML   ++    R  A G A  G  + L  
Sbjct: 184 FAFSGTYTLLFVAR-TLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLV 242

Query: 163 LSPLGQLLQDRYGWRGGFLILGGL-LLNCCVCAALMRPLVVTAQPGSGPP 211
            +P G ++ +  G    FLIL  L LL+  +   +++P  V+ +   G P
Sbjct: 243 GAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTP 292


>gi|42476325 solute carrier family 18 (vesicular monoamine), member
           2 [Homo sapiens]
          Length = 514

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 71/345 (20%), Positives = 129/345 (37%), Gaps = 33/345 (9%)

Query: 74  TGPLCSVCVNRFGCRPVMLVGG---LFASLGMVAASFCRSIIQVYLTTGVITGLGLALNF 130
           T P   +  NR G  P+ +  G   +F S  M A S   + +   L    + G+G + + 
Sbjct: 145 TNPFIGLLTNRIGY-PIPIFAGFCIMFVSTIMFAFSSSYAFL---LIARSLQGIGSSCSS 200

Query: 131 QPSLIMLNRYFSKRRPMAN--GLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGL-L 187
              + ML   ++      N  G+A  G  + +    P G +L +  G    FL+L  L L
Sbjct: 201 VAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVL 260

Query: 188 LNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPV 247
           L+  +   +++P  V  +   G P  +  L D  +    G + +A     M+      P+
Sbjct: 261 LDGAIQLFVLQPSRVQPESQKGTPL-TTLLKDPYILIAAGSICFANMGIAMLEPAL--PI 317

Query: 248 FVV----SYAKDLGVPDTKAAFLLTI-LGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSM 302
           +++    S    LGV    A+    I      I A     ++  L              M
Sbjct: 318 WMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCAL------------LGM 365

Query: 303 FFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHK---FSSAIGLV 359
              G++ L    A +  GL+      G + GMV +    ++  +V       + S   + 
Sbjct: 366 IIVGVSILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIA 425

Query: 360 LLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLL 404
            +   +   +GP +GG +  A      + I+   ++L + L   L
Sbjct: 426 DVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDILFAPLCFFL 470



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 48/199 (24%), Positives = 76/199 (38%), Gaps = 18/199 (9%)

Query: 226 RGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVA 285
           R   L+  A   MV      P    S  KDL   + +   L      + +   P  G + 
Sbjct: 94  RDLTLHQTATQHMVTNASAVPSDCPSEDKDLLNENVQVGLLFASKATVQLITNPFIGLLT 153

Query: 286 G-LGKVRPYSVYLFS-FSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVL 343
             +G    Y + +F+ F + F      A S++  Y  L++     GI           +L
Sbjct: 154 NRIG----YPIPIFAGFCIMFVSTIMFAFSSS--YAFLLIARSLQGIGSSCSSVAGMGML 207

Query: 344 MAI-VGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLT-SSLI 401
            ++     +  + +G+ L   A+ VLVGPP G  L        Y F+   A  L  ++L+
Sbjct: 208 ASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVL--------YEFVGKTAPFLVLAALV 259

Query: 402 LLLGNFFCIRKKPKEPQPE 420
           LL G       +P   QPE
Sbjct: 260 LLDGAIQLFVLQPSRVQPE 278


>gi|16445357 hypothetical protein LOC116843 [Homo sapiens]
          Length = 456

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 67/358 (18%), Positives = 121/358 (33%), Gaps = 31/358 (8%)

Query: 91  MLVGGLFASLGMVAASFCRS-------IIQVYLTTGVITGLGLALNFQPSLIMLNRYFSK 143
           M V G+F S G+                I +     V+  +  A     S  +L + F  
Sbjct: 102 MFVAGMFVSGGVTILFGVLDRVPDGPVFIAMCFLVRVMDAVSFAAAMTASSSILAKAFPN 161

Query: 144 RRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMRPLVVT 203
                 G     S + L    P+G  L   +G+   F++LG ++L       LM PL + 
Sbjct: 162 NVATVLGSLETFSGLGLILGPPVGGFLYQSFGYEVPFIVLGCVVL-------LMVPLNMY 214

Query: 204 AQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKA 263
             P             L      G + + + +     G F+ P   +   +   +P    
Sbjct: 215 ILPNYESDPGEHSFWKLIALPKVGLIAFVINSLSSCFG-FLDPTLSLFVLEKFNLPAGYV 273

Query: 264 AFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSF-SMFFNGLADLAGST-----AGD 317
             +   +      + P  G ++   K  P   +L  F ++   G   L G          
Sbjct: 274 GLVFLGMALSYAISSPLFGLLS--DKRPPLRKWLLVFGNLITAGCYMLLGPVPILHIKSQ 331

Query: 318 YGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAI-------GLVLLMEAVAVLVG 370
              LV+  +  G+S GM     F  +++    + F   +       GL   M ++   +G
Sbjct: 332 LWLLVLILVVSGLSAGMSIIPTFPEILSCAHENGFEEGLSTLGLVSGLFSAMWSIGAFMG 391

Query: 371 PPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPEVAAAEEEK 428
           P  GG L +    + +   + G   L S L + L       ++ +     + + EEE+
Sbjct: 392 PTLGGFLYEKIG-FEWAAAIQGLWALISGLAMGLFYLLEYSRRKRSKSQNILSTEEER 448


>gi|34330168 olfactory receptor, family 6, subfamily A, member 2
           [Homo sapiens]
          Length = 327

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 5/78 (6%)

Query: 5   VVDEGPTGVKAPDGGW--GWAV-LFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSD-- 59
           V+  G   V+   G W  G+ + +   F+I+G SY  P  ++ FF ++     +  +D  
Sbjct: 139 VIVSGRLCVQMAAGSWAGGFGISMVKVFLISGLSYCGPNIINHFFCDVSPLLNLSCTDMS 198

Query: 60  TAWISSILLAMLYGTGPL 77
           TA ++  +LA+    GPL
Sbjct: 199 TAELTDFILAIFILLGPL 216


>gi|167614500 lymphocyte-activation protein 3 precursor [Homo
           sapiens]
          Length = 525

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 4/79 (5%)

Query: 384 YMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPEVAAAEEEKLHKPPADSGVDLREV 443
           ++ +F++ G      SL+LL+   F      ++ +P   +A E+ +H P A S ++  E 
Sbjct: 449 HLLLFLILGV----LSLLLLVTGAFGFHLWRRQWRPRRFSALEQGIHPPQAQSKIEELEQ 504

Query: 444 EHFLKAEPEKNGEVVHTPE 462
           E   + EPE   E    PE
Sbjct: 505 EPEPEPEPEPEPEPEPEPE 523


>gi|38569457 solute carrier family 12, member 8 [Homo sapiens]
          Length = 714

 Score = 30.4 bits (67), Expect = 3.6
 Identities = 21/89 (23%), Positives = 39/89 (43%), Gaps = 4/89 (4%)

Query: 42  VSVFFKELIQEFGIGYSDTAWISSILL--AMLYGT--GPLCSVCVNRFGCRPVMLVGGLF 97
           V   F E  Q+  +      W + + +   +L+GT  G   S  +N FG    +  G L 
Sbjct: 7   VQELFHEAAQQDALAQPQPWWKTQLFMWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLV 66

Query: 98  ASLGMVAASFCRSIIQVYLTTGVITGLGL 126
            + G++   F  S + +     V++G+G+
Sbjct: 67  GNTGVLLGMFLVSFVILVALVTVLSGIGV 95


>gi|166064062 tumor suppressing subtransferable candidate 5 [Homo
           sapiens]
          Length = 424

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 51/225 (22%), Positives = 84/225 (37%), Gaps = 10/225 (4%)

Query: 224 RDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGF 283
           R    +L  V A+  +  LF+    V   ++ LG+      +L T  G + +   P  G 
Sbjct: 22  RSSVILLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYLQTTFGVLQLLGGPVFGR 81

Query: 284 VAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVL 343
            A     R      F  ++    L   A S A     L+      G     + A Q  V+
Sbjct: 82  FADQRGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMHTLPAAQM-VI 140

Query: 344 MAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILL 403
             +    +  +A+G + L   V V++G   GG L+ A  +     + A A +L + L   
Sbjct: 141 TDLSAPEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVL--- 197

Query: 404 LGNFFCIRKKPKEPQPEVAAAEEEKLHKPPADSGVDLREVEHFLK 448
             +F CI    K  + +  A     L   P  S  DL+ +   L+
Sbjct: 198 --SFTCIPASTKGAKTDAQA----PLPGGPRASVFDLKAIASLLR 236


>gi|166064060 tumor suppressing subtransferable candidate 5 [Homo
           sapiens]
          Length = 424

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 51/225 (22%), Positives = 84/225 (37%), Gaps = 10/225 (4%)

Query: 224 RDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGF 283
           R    +L  V A+  +  LF+    V   ++ LG+      +L T  G + +   P  G 
Sbjct: 22  RSSVILLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYLQTTFGVLQLLGGPVFGR 81

Query: 284 VAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVL 343
            A     R      F  ++    L   A S A     L+      G     + A Q  V+
Sbjct: 82  FADQRGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMHTLPAAQM-VI 140

Query: 344 MAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILL 403
             +    +  +A+G + L   V V++G   GG L+ A  +     + A A +L + L   
Sbjct: 141 TDLSAPEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVL--- 197

Query: 404 LGNFFCIRKKPKEPQPEVAAAEEEKLHKPPADSGVDLREVEHFLK 448
             +F CI    K  + +  A     L   P  S  DL+ +   L+
Sbjct: 198 --SFTCIPASTKGAKTDAQA----PLPGGPRASVFDLKAIASLLR 236


>gi|187608446 phosphatidylinositol glycan anchor biosynthesis, class
           G isoform 1 [Homo sapiens]
          Length = 983

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 15/89 (16%)

Query: 153 AAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMRPLVVTAQPGSGPPR 212
           +A S  + C LS L           GG ++L   LL C + + L   LV    P   P  
Sbjct: 493 SAESSCYFCGLSWLAA---------GGVMVLASALL-CVIVSVLTNVLVGGNTPRKNPMH 542

Query: 213 PSRRLLDLSVFRDRGFVLYAVAASVMVLG 241
           PS R  +L +      +L   A  V+ LG
Sbjct: 543 PSSRWSELDL-----LILLGTAGHVLSLG 566


>gi|187608438 phosphatidylinositol glycan anchor biosynthesis, class
           G isoform 2 [Homo sapiens]
          Length = 975

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 15/89 (16%)

Query: 153 AAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMRPLVVTAQPGSGPPR 212
           +A S  + C LS L           GG ++L   LL C + + L   LV    P   P  
Sbjct: 485 SAESSCYFCGLSWLAA---------GGVMVLASALL-CVIVSVLTNVLVGGNTPRKNPMH 534

Query: 213 PSRRLLDLSVFRDRGFVLYAVAASVMVLG 241
           PS R  +L +      +L   A  V+ LG
Sbjct: 535 PSSRWSELDL-----LILLGTAGHVLSLG 558


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.144    0.444 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,485,530
Number of Sequences: 37866
Number of extensions: 837368
Number of successful extensions: 2856
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 2790
Number of HSP's gapped (non-prelim): 58
length of query: 465
length of database: 18,247,518
effective HSP length: 106
effective length of query: 359
effective length of database: 14,233,722
effective search space: 5109906198
effective search space used: 5109906198
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.