Guide to the Human Genome
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Search of human proteins with 4759046

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4759046 RNA polymerase I subunit isoform 2 [Homo sapiens]
         (342 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4759046 RNA polymerase I subunit isoform 2 [Homo sapiens]          694   0.0  
gi|42560246 RNA polymerase I subunit isoform 1 [Homo sapiens]         619   e-177
gi|14702171 DNA directed RNA polymerase II polypeptide C [Homo s...   100   1e-21
gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]     55   1e-07
gi|116256455 zinc finger protein 429 [Homo sapiens]                    46   6e-05
gi|148664226 plakophilin 2 isoform 2b [Homo sapiens]                   42   6e-04
gi|239756590 PREDICTED: hypothetical protein XP_002344942 [Homo ...    40   0.002
gi|239751084 PREDICTED: hypothetical protein XP_002347710 [Homo ...    40   0.002
gi|239745573 PREDICTED: hypothetical protein XP_002344133 [Homo ...    40   0.002
gi|148277022 selenoprotein P isoform 2 [Homo sapiens]                  38   0.015
gi|11038659 ADAM metallopeptidase with thrombospondin type 1 mot...    37   0.020
gi|224451040 Yip1 interacting factor homolog B isoform 7 [Homo s...    36   0.057
gi|144953913 zinc finger protein 714 [Homo sapiens]                    36   0.057
gi|33356179 transcription termination factor, RNA polymerase I [...    35   0.13 
gi|169204982 PREDICTED: hypothetical protein [Homo sapiens]            34   0.22 
gi|169205503 PREDICTED: hypothetical protein [Homo sapiens]            34   0.22 
gi|169204452 PREDICTED: hypothetical protein [Homo sapiens]            34   0.22 
gi|59859882 baculoviral IAP repeat-containing protein 5 isoform ...    30   2.4  
gi|45331213 RAN binding protein 6 [Homo sapiens]                       30   3.1  
gi|224831257 importin 13 [Homo sapiens]                                29   5.3  
gi|54873613 agrin [Homo sapiens]                                       29   5.3  
gi|154091028 sorting nexin 29 [Homo sapiens]                           29   5.3  
gi|7661858 Rho GTPase activating protein 11A isoform 1 [Homo sap...    29   7.0  
gi|40788018 Rho GTPase activating protein 11A isoform 2 [Homo sa...    29   7.0  
gi|217035140 zinc finger protein 669 isoform 2 [Homo sapiens]          28   9.1  
gi|217035138 zinc finger protein 669 isoform 1 [Homo sapiens]          28   9.1  

>gi|4759046 RNA polymerase I subunit isoform 2 [Homo sapiens]
          Length = 342

 Score =  694 bits (1792), Expect = 0.0
 Identities = 342/342 (100%), Positives = 342/342 (100%)

Query: 1   MAASQAVEEMRSRVVLGEFGVRNVHTTDFPGNYSGYDDAWDQDRFEKNFRVDVVHMDENS 60
           MAASQAVEEMRSRVVLGEFGVRNVHTTDFPGNYSGYDDAWDQDRFEKNFRVDVVHMDENS
Sbjct: 1   MAASQAVEEMRSRVVLGEFGVRNVHTTDFPGNYSGYDDAWDQDRFEKNFRVDVVHMDENS 60

Query: 61  LEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPR 120
           LEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPR
Sbjct: 61  LEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPR 120

Query: 121 LFEYRNQGDEEGTEIDTLQFRLQVRCTRNPHAAKDSSDPNELYVNHKVYTRHMTWIPLGN 180
           LFEYRNQGDEEGTEIDTLQFRLQVRCTRNPHAAKDSSDPNELYVNHKVYTRHMTWIPLGN
Sbjct: 121 LFEYRNQGDEEGTEIDTLQFRLQVRCTRNPHAAKDSSDPNELYVNHKVYTRHMTWIPLGN 180

Query: 181 QADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDIT 240
           QADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDIT
Sbjct: 181 QADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDIT 240

Query: 241 LLEPVEGEAAEELSRCFSPGVIEVQEVQGKKVARVANPRLDTFSREIFRNEKLKKVVRLA 300
           LLEPVEGEAAEELSRCFSPGVIEVQEVQGKKVARVANPRLDTFSREIFRNEKLKKVVRLA
Sbjct: 241 LLEPVEGEAAEELSRCFSPGVIEVQEVQGKKVARVANPRLDTFSREIFRNEKLKKVVRLA 300

Query: 301 RVRDHYICKKDLLAAVAHTCNPSTLGGQGEWITGSRERDHPG 342
           RVRDHYICKKDLLAAVAHTCNPSTLGGQGEWITGSRERDHPG
Sbjct: 301 RVRDHYICKKDLLAAVAHTCNPSTLGGQGEWITGSRERDHPG 342


>gi|42560246 RNA polymerase I subunit isoform 1 [Homo sapiens]
          Length = 346

 Score =  619 bits (1595), Expect = e-177
 Identities = 307/307 (100%), Positives = 307/307 (100%)

Query: 1   MAASQAVEEMRSRVVLGEFGVRNVHTTDFPGNYSGYDDAWDQDRFEKNFRVDVVHMDENS 60
           MAASQAVEEMRSRVVLGEFGVRNVHTTDFPGNYSGYDDAWDQDRFEKNFRVDVVHMDENS
Sbjct: 1   MAASQAVEEMRSRVVLGEFGVRNVHTTDFPGNYSGYDDAWDQDRFEKNFRVDVVHMDENS 60

Query: 61  LEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPR 120
           LEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPR
Sbjct: 61  LEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPR 120

Query: 121 LFEYRNQGDEEGTEIDTLQFRLQVRCTRNPHAAKDSSDPNELYVNHKVYTRHMTWIPLGN 180
           LFEYRNQGDEEGTEIDTLQFRLQVRCTRNPHAAKDSSDPNELYVNHKVYTRHMTWIPLGN
Sbjct: 121 LFEYRNQGDEEGTEIDTLQFRLQVRCTRNPHAAKDSSDPNELYVNHKVYTRHMTWIPLGN 180

Query: 181 QADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDIT 240
           QADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDIT
Sbjct: 181 QADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDIT 240

Query: 241 LLEPVEGEAAEELSRCFSPGVIEVQEVQGKKVARVANPRLDTFSREIFRNEKLKKVVRLA 300
           LLEPVEGEAAEELSRCFSPGVIEVQEVQGKKVARVANPRLDTFSREIFRNEKLKKVVRLA
Sbjct: 241 LLEPVEGEAAEELSRCFSPGVIEVQEVQGKKVARVANPRLDTFSREIFRNEKLKKVVRLA 300

Query: 301 RVRDHYI 307
           RVRDHYI
Sbjct: 301 RVRDHYI 307


>gi|14702171 DNA directed RNA polymerase II polypeptide C [Homo
           sapiens]
          Length = 275

 Score =  100 bits (250), Expect = 1e-21
 Identities = 64/199 (32%), Positives = 105/199 (52%), Gaps = 15/199 (7%)

Query: 51  VDVVHMDENSLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRL 110
           V +  + + +++F +   D A+AN+ RR+ +AEVP +A++ V +  N+S++ DE +AHRL
Sbjct: 9   VRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRL 68

Query: 111 GLIPIHADPRLFEYRNQGD---EEGTEIDTLQFRLQVRCTRNPHAAKDSSDPNELYVNHK 167
           GLIP+ +D  + + +   D   EE     +++F L VRC         + D      +  
Sbjct: 69  GLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRC---------NEDQTRHVTSRD 119

Query: 168 VYTRHMTWIPL-GNQADLFPEGTIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFS 226
           + +     IP+     D  P   +    DDILI +LR GQE+ L  +  KG GK+HAK++
Sbjct: 120 LISNSPRVIPVTSRNRDNDPNDYVE--QDDILIVKLRKGQELRLRAYAKKGFGKEHAKWN 177

Query: 227 PVATASYRLLPDITLLEPV 245
           P A  ++   PD  L   V
Sbjct: 178 PTAGVAFEYDPDNALRHTV 196


>gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]
          Length = 374

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 23/30 (76%), Positives = 25/30 (83%)

Query: 313 LAAVAHTCNPSTLGGQGEWITGSRERDHPG 342
           L AVAH CNPSTLGG+G WIT S +RDHPG
Sbjct: 345 LGAVAHACNPSTLGGRGGWITRSGDRDHPG 374


>gi|116256455 zinc finger protein 429 [Homo sapiens]
          Length = 674

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 25/52 (48%), Positives = 30/52 (57%), Gaps = 2/52 (3%)

Query: 291 EKLKKVVRLARVRDHYICKKDLLAAVAHTCNPSTLGGQGEWITGSRERDHPG 342
           E  K   R +R+  H   K   +  VAH CNPSTLGG+G  IT S +RD PG
Sbjct: 625 ECAKAFTRSSRLTQHK--KIHRMGVVAHACNPSTLGGRGGRITRSGDRDRPG 674


>gi|148664226 plakophilin 2 isoform 2b [Homo sapiens]
          Length = 881

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 20/27 (74%), Positives = 20/27 (74%)

Query: 315 AVAHTCNPSTLGGQGEWITGSRERDHP 341
           AVAH CNPSTLGGQG  IT S  RD P
Sbjct: 474 AVAHACNPSTLGGQGGRITRSGVRDQP 500


>gi|239756590 PREDICTED: hypothetical protein XP_002344942 [Homo
           sapiens]
          Length = 120

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 21/33 (63%), Positives = 24/33 (72%), Gaps = 1/33 (3%)

Query: 306 YICKKDL-LAAVAHTCNPSTLGGQGEWITGSRE 337
           YI K+ L L  VAHT NPSTLGG+G WIT  +E
Sbjct: 74  YIKKERLWLGPVAHTYNPSTLGGRGGWITRGQE 106


>gi|239751084 PREDICTED: hypothetical protein XP_002347710 [Homo
           sapiens]
          Length = 120

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 21/33 (63%), Positives = 24/33 (72%), Gaps = 1/33 (3%)

Query: 306 YICKKDL-LAAVAHTCNPSTLGGQGEWITGSRE 337
           YI K+ L L  VAHT NPSTLGG+G WIT  +E
Sbjct: 74  YIKKERLWLGPVAHTYNPSTLGGRGGWITRGQE 106


>gi|239745573 PREDICTED: hypothetical protein XP_002344133 [Homo
           sapiens]
          Length = 120

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 21/33 (63%), Positives = 24/33 (72%), Gaps = 1/33 (3%)

Query: 306 YICKKDL-LAAVAHTCNPSTLGGQGEWITGSRE 337
           YI K+ L L  VAHT NPSTLGG+G WIT  +E
Sbjct: 74  YIKKERLWLGPVAHTYNPSTLGGRGGWITRGQE 106


>gi|148277022 selenoprotein P isoform 2 [Homo sapiens]
          Length = 411

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 17/21 (80%), Positives = 17/21 (80%)

Query: 313 LAAVAHTCNPSTLGGQGEWIT 333
           L AVAH CNPSTLGGQG  IT
Sbjct: 5   LDAVAHACNPSTLGGQGRRIT 25


>gi|11038659 ADAM metallopeptidase with thrombospondin type 1 motif,
           2 isoform 2 [Homo sapiens]
          Length = 566

 Score = 37.4 bits (85), Expect = 0.020
 Identities = 15/18 (83%), Positives = 15/18 (83%)

Query: 315 AVAHTCNPSTLGGQGEWI 332
           AVAH C PSTLGGQG WI
Sbjct: 548 AVAHACYPSTLGGQGRWI 565


>gi|224451040 Yip1 interacting factor homolog B isoform 7 [Homo
           sapiens]
          Length = 291

 Score = 35.8 bits (81), Expect = 0.057
 Identities = 17/24 (70%), Positives = 18/24 (75%)

Query: 312 LLAAVAHTCNPSTLGGQGEWITGS 335
           L  AVAH CNPSTLGG+G  IT S
Sbjct: 264 LPGAVAHACNPSTLGGRGGRITRS 287


>gi|144953913 zinc finger protein 714 [Homo sapiens]
          Length = 555

 Score = 35.8 bits (81), Expect = 0.057
 Identities = 16/27 (59%), Positives = 18/27 (66%)

Query: 316 VAHTCNPSTLGGQGEWITGSRERDHPG 342
           VAH CNP+TL G GE I  S  +D PG
Sbjct: 507 VAHACNPNTLRGLGEQIARSGVQDQPG 533


>gi|33356179 transcription termination factor, RNA polymerase I
           [Homo sapiens]
          Length = 905

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 13/17 (76%), Positives = 14/17 (82%)

Query: 316 VAHTCNPSTLGGQGEWI 332
           +AH CN STLGGQG WI
Sbjct: 888 MAHACNSSTLGGQGRWI 904


>gi|169204982 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 117

 Score = 33.9 bits (76), Expect = 0.22
 Identities = 14/24 (58%), Positives = 17/24 (70%)

Query: 314 AAVAHTCNPSTLGGQGEWITGSRE 337
           + V HTCNPSTLGG+G  I   +E
Sbjct: 80  SVVPHTCNPSTLGGRGGQIPSGQE 103


>gi|169205503 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 117

 Score = 33.9 bits (76), Expect = 0.22
 Identities = 14/24 (58%), Positives = 17/24 (70%)

Query: 314 AAVAHTCNPSTLGGQGEWITGSRE 337
           + V HTCNPSTLGG+G  I   +E
Sbjct: 80  SVVPHTCNPSTLGGRGGQIPSGQE 103


>gi|169204452 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 117

 Score = 33.9 bits (76), Expect = 0.22
 Identities = 14/24 (58%), Positives = 17/24 (70%)

Query: 314 AAVAHTCNPSTLGGQGEWITGSRE 337
           + V HTCNPSTLGG+G  I   +E
Sbjct: 80  SVVPHTCNPSTLGGRGGQIPSGQE 103


>gi|59859882 baculoviral IAP repeat-containing protein 5 isoform 3
           [Homo sapiens]
          Length = 165

 Score = 30.4 bits (67), Expect = 2.4
 Identities = 13/25 (52%), Positives = 16/25 (64%)

Query: 316 VAHTCNPSTLGGQGEWITGSRERDH 340
           VA+ CN STLGG+G  IT    + H
Sbjct: 79  VAYACNTSTLGGRGGRITREEHKKH 103


>gi|45331213 RAN binding protein 6 [Homo sapiens]
          Length = 1105

 Score = 30.0 bits (66), Expect = 3.1
 Identities = 14/51 (27%), Positives = 25/51 (49%)

Query: 68   IDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHAD 118
            I  A +   + ++  E    A+ K+L +    +  DE+L H L  +P+H D
Sbjct: 963  IKCANSKTKKNVIATENCISAIGKILKFKPNCVNVDEVLPHWLSWLPLHED 1013


>gi|224831257 importin 13 [Homo sapiens]
          Length = 963

 Score = 29.3 bits (64), Expect = 5.3
 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 15/75 (20%)

Query: 239 ITLLEPVEGEAAEELSRCF---------------SPGVIEVQEVQGKKVARVANPRLDTF 283
           I +LE + G+A+  L  CF               S  + E  +  G   AR++  + DTF
Sbjct: 867 IAVLEAIGGQASRSLMDCFADILFALNKHCFSLLSMWIKEALQPPGFPSARLSPEQKDTF 926

Query: 284 SREIFRNEKLKKVVR 298
           S++I R    K+ V+
Sbjct: 927 SQQILRERVNKRRVK 941


>gi|54873613 agrin [Homo sapiens]
          Length = 2045

 Score = 29.3 bits (64), Expect = 5.3
 Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 13/58 (22%)

Query: 260  GVIEVQEVQGKKV---ARVANPRLDTFSR----------EIFRNEKLKKVVRLARVRD 304
            GV+E++ V+G+++     +A+P+ + F            ++FRN  +KK  R  R+RD
Sbjct: 1136 GVLELEGVEGQELFYTPEMADPKSELFGETARSIESTLDDLFRNSDVKKDFRSVRLRD 1193


>gi|154091028 sorting nexin 29 [Homo sapiens]
          Length = 428

 Score = 29.3 bits (64), Expect = 5.3
 Identities = 13/35 (37%), Positives = 22/35 (62%)

Query: 238 DITLLEPVEGEAAEELSRCFSPGVIEVQEVQGKKV 272
           ++T+ E   GE AEEL+  +   +IEV E+ G+ +
Sbjct: 184 EVTVAEQKPGEIAEELASSYERKLIEVAEMHGELI 218


>gi|7661858 Rho GTPase activating protein 11A isoform 1 [Homo
           sapiens]
          Length = 1023

 Score = 28.9 bits (63), Expect = 7.0
 Identities = 13/35 (37%), Positives = 22/35 (62%)

Query: 265 QEVQGKKVARVANPRLDTFSREIFRNEKLKKVVRL 299
           + + GKKV RV + +   FS +I   EK+++ +RL
Sbjct: 403 KRIAGKKVCRVESGKAGCFSPKISHKEKVRRSLRL 437


>gi|40788018 Rho GTPase activating protein 11A isoform 2 [Homo
           sapiens]
          Length = 501

 Score = 28.9 bits (63), Expect = 7.0
 Identities = 13/35 (37%), Positives = 22/35 (62%)

Query: 265 QEVQGKKVARVANPRLDTFSREIFRNEKLKKVVRL 299
           + + GKKV RV + +   FS +I   EK+++ +RL
Sbjct: 403 KRIAGKKVCRVESGKAGCFSPKISHKEKVRRSLRL 437


>gi|217035140 zinc finger protein 669 isoform 2 [Homo sapiens]
          Length = 378

 Score = 28.5 bits (62), Expect = 9.1
 Identities = 11/12 (91%), Positives = 11/12 (91%)

Query: 321 NPSTLGGQGEWI 332
           NPSTLGGQG WI
Sbjct: 366 NPSTLGGQGVWI 377


>gi|217035138 zinc finger protein 669 isoform 1 [Homo sapiens]
          Length = 464

 Score = 28.5 bits (62), Expect = 9.1
 Identities = 11/12 (91%), Positives = 11/12 (91%)

Query: 321 NPSTLGGQGEWI 332
           NPSTLGGQG WI
Sbjct: 452 NPSTLGGQGVWI 463


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,909,924
Number of Sequences: 37866
Number of extensions: 552249
Number of successful extensions: 985
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 959
Number of HSP's gapped (non-prelim): 26
length of query: 342
length of database: 18,247,518
effective HSP length: 103
effective length of query: 239
effective length of database: 14,347,320
effective search space: 3429009480
effective search space used: 3429009480
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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