Guide to the Human Genome
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Search of human proteins with 4758902

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758902 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase
4 [Homo sapiens]
         (469 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758902 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4...   956   0.0  
gi|118582286 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase...   725   0.0  
gi|4758900 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3...   670   0.0  
gi|224282149 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase...   654   0.0  
gi|64762445 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase ...   648   0.0  
gi|64762406 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase ...   648   0.0  
gi|4505753 bisphosphoglycerate mutase 1 [Homo sapiens]                 44   4e-04
gi|71274132 bisphosphoglycerate mutase 4 [Homo sapiens]                39   0.010
gi|50593010 bisphosphoglycerate mutase 2 [Homo sapiens]                38   0.023
gi|20070384 phosphoglycerate mutase family member 5 [Homo sapiens]     36   0.066
gi|94721261 2',3'-cyclic nucleotide 3' phosphodiesterase [Homo s...    33   0.73 
gi|31377775 glutamate dehydrogenase 2 [Homo sapiens]                   32   0.95 
gi|34452721 GA binding protein transcription factor, alpha subun...    32   1.2  
gi|4559408 colony stimulating factor 2 receptor, beta precursor ...    31   2.1  
gi|4885281 glutamate dehydrogenase 1 [Homo sapiens]                    29   8.0  
gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2 ...    29   8.0  

>gi|4758902 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
           [Homo sapiens]
          Length = 469

 Score =  956 bits (2470), Expect = 0.0
 Identities = 469/469 (100%), Positives = 469/469 (100%)

Query: 1   MASPRELTQNPLKKIWMPYSNGRPALHACQRGVCMTNCPTLIVMVGLPARGKTYISKKLT 60
           MASPRELTQNPLKKIWMPYSNGRPALHACQRGVCMTNCPTLIVMVGLPARGKTYISKKLT
Sbjct: 1   MASPRELTQNPLKKIWMPYSNGRPALHACQRGVCMTNCPTLIVMVGLPARGKTYISKKLT 60

Query: 61  RYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSE 120
           RYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSE
Sbjct: 61  RYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSE 120

Query: 121 EGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYV 180
           EGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYV
Sbjct: 121 EGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYV 180

Query: 181 NRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVY 240
           NRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVY
Sbjct: 181 NRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVY 240

Query: 241 YLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVW 300
           YLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVW
Sbjct: 241 YLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVW 300

Query: 301 TSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRY 360
           TSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRY
Sbjct: 301 TSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRY 360

Query: 361 PKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTV 420
           PKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTV
Sbjct: 361 PKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTV 420

Query: 421 LKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ 469
           LKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
Sbjct: 421 LKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ 469


>gi|118582286 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
           [Homo sapiens]
          Length = 471

 Score =  725 bits (1871), Expect = 0.0
 Identities = 353/466 (75%), Positives = 404/466 (86%), Gaps = 5/466 (1%)

Query: 6   ELTQNPLKKIWMPYSNGRPALHACQRGVCM---TNCPTLIVMVGLPARGKTYISKKLTRY 62
           ELTQ  L+KIW+P+S+G   L   +RG  +   TN PT+++MVGLPARGKTYIS KLTRY
Sbjct: 7   ELTQTRLQKIWIPHSSGSSRLQR-RRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRY 65

Query: 63  LNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSEEG 122
           LNWIG PT+ FN+GQYRR+ V +YK++EFFLPDN E L+IRKQCALAAL+DV  +LS E 
Sbjct: 66  LNWIGTPTKVFNLGQYRREAV-SYKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEE 124

Query: 123 GHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYVNR 182
           GHVAVFDATNTTRERR+ I  F +++GYK FF+ESIC DP +IA NI QVKLGSPDY++ 
Sbjct: 125 GHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDC 184

Query: 183 DSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVYYL 242
           D ++  EDF++RIECYE +Y+ LDE+LD  LSYIKI DVG  Y+VNRV DHIQSR VYYL
Sbjct: 185 DREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYL 244

Query: 243 MNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVWTS 302
           MNIHVTPRSIYLCRHGESELN++GRIGGD GLS RG+++A +LA FI  Q I  LKVWTS
Sbjct: 245 MNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTS 304

Query: 303 QMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRYPK 362
            MKRTIQTAEALGVPYEQWK LNEIDAGVCEEMTYEEIQ++YP EFALRDQDKYRYRYPK
Sbjct: 305 HMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPK 364

Query: 363 GESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTVLK 422
           GESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDK++++LPYLKCPLHTVLK
Sbjct: 365 GESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLK 424

Query: 423 LTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAH 468
           LTPVAYGCKVESI+LNV AVNTHR++P+NVDI+R PEEAL TVPAH
Sbjct: 425 LTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAH 470


>gi|4758900 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
           isoform 1 [Homo sapiens]
          Length = 520

 Score =  670 bits (1729), Expect = 0.0
 Identities = 321/450 (71%), Positives = 391/450 (86%), Gaps = 5/450 (1%)

Query: 4   PRELTQNPLKKIWMPYSNGRPAL-HACQRGVCMTNCPTLIVMVGLPARGKTYISKKLTRY 62
           P ELTQ+ ++KIW+P  + RP+L  +C  G  +TN PT+IVMVGLPARGKTYISKKLTRY
Sbjct: 2   PLELTQSRVQKIWVPVDH-RPSLPRSC--GPKLTNSPTVIVMVGLPARGKTYISKKLTRY 58

Query: 63  LNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSEEG 122
           LNWIGVPT+ FNVG+YRR+ VK Y S+ FF PDNEE +K+RKQCALAALRDV+ +L++EG
Sbjct: 59  LNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEG 118

Query: 123 GHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYVNR 182
           G +AVFDATNTTRERR  I +F ++N +K FF+ES+C DP V+A+NI++VK+ SPDY + 
Sbjct: 119 GQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDC 178

Query: 183 DSDEATEDFMRRIECYENSYESLDED-LDRDLSYIKIMDVGQSYVVNRVADHIQSRIVYY 241
           +S EA +DFM+RI CYE SY+ LD D  DRDLS IK++DVG+ ++VNRV DHIQSRIVYY
Sbjct: 179 NSAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYY 238

Query: 242 LMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVWT 301
           LMNIHV PR+IYLCRHGE+E NL+GRIGGD GLS RG++FA +L++F+ +QN+KDL+VWT
Sbjct: 239 LMNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWT 298

Query: 302 SQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRYP 361
           SQ+K TIQTAEAL +PYEQWK LNEIDAGVCEE+TYEEI+D YP E+ALR+QDKY YRYP
Sbjct: 299 SQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYP 358

Query: 362 KGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTVL 421
            GESY+DLVQRLEPVIMELERQENVLVICHQAV+RCLLAYFLDK+AE++PYLKCPLHTVL
Sbjct: 359 TGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVL 418

Query: 422 KLTPVAYGCKVESIFLNVAAVNTHRDRPQN 451
           KLTPVAYGC+VESI+LNV +V THR+R ++
Sbjct: 419 KLTPVAYGCRVESIYLNVESVCTHRERSED 448


>gi|224282149 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
           isoform 2 [Homo sapiens]
          Length = 500

 Score =  654 bits (1688), Expect = 0.0
 Identities = 311/429 (72%), Positives = 374/429 (87%), Gaps = 3/429 (0%)

Query: 24  PALHACQRGVCMTNCPTLIVMVGLPARGKTYISKKLTRYLNWIGVPTREFNVGQYRRDVV 83
           P   AC  G  +TN PT+IVMVGLPARGKTYISKKLTRYLNWIGVPT+ FNVG+YRR+ V
Sbjct: 2   PFRKAC--GPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAV 59

Query: 84  KTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSEEGGHVAVFDATNTTRERRATIFN 143
           K Y S+ FF PDNEE +K+RKQCALAALRDV+ +L++EGG +AVFDATNTTRERR  I +
Sbjct: 60  KQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILH 119

Query: 144 FGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYVNRDSDEATEDFMRRIECYENSYE 203
           F ++N +K FF+ES+C DP V+A+NI++VK+ SPDY + +S EA +DFM+RI CYE SY+
Sbjct: 120 FAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQ 179

Query: 204 SLDED-LDRDLSYIKIMDVGQSYVVNRVADHIQSRIVYYLMNIHVTPRSIYLCRHGESEL 262
            LD D  DRDLS IK++DVG+ ++VNRV DHIQSRIVYYLMNIHV PR+IYLCRHGE+E 
Sbjct: 180 PLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEH 239

Query: 263 NLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVWTSQMKRTIQTAEALGVPYEQWK 322
           NL+GRIGGD GLS RG++FA +L++F+ +QN+KDL+VWTSQ+K TIQTAEAL +PYEQWK
Sbjct: 240 NLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWK 299

Query: 323 VLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELER 382
            LNEIDAGVCEE+TYEEI+D YP E+ALR+QDKY YRYP GESY+DLVQRLEPVIMELER
Sbjct: 300 ALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELER 359

Query: 383 QENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTVLKLTPVAYGCKVESIFLNVAAV 442
           QENVLVICHQAV+RCLLAYFLDK+AE++PYLKCPLHTVLKLTPVAYGC+VESI+LNV +V
Sbjct: 360 QENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESV 419

Query: 443 NTHRDRPQN 451
            THR+R ++
Sbjct: 420 CTHRERSED 428


>gi|64762445 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
           isoform b [Homo sapiens]
          Length = 471

 Score =  648 bits (1672), Expect = 0.0
 Identities = 313/451 (69%), Positives = 373/451 (82%), Gaps = 5/451 (1%)

Query: 21  NGRPALHACQRGVCMTNCPTLIVMVGLPARGKTYISKKLTRYLNWIGVPTREFNVGQYRR 80
           N R +   C     MTN PTLIVM+GLPARGKTY+SKKLTRYLNWIGVPT+ FN+G YRR
Sbjct: 20  NLRMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRR 79

Query: 81  DVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSEEGGHVAVFDATNTTRERRAT 140
           + VK+YKS++FF  DNEE +KIRKQCAL AL DV+ +L+EE G +AVFDATNTTRERR  
Sbjct: 80  EAVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDM 139

Query: 141 IFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYVNRDSDEATEDFMRRIECYEN 200
           I NF EQN +K FFVES+C DP+VIAANI++VK+ SPDY  R+ +   EDF++RIECY+ 
Sbjct: 140 ILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKV 199

Query: 201 SYESLDED-LDRDLSYIKIMDVGQSYVVNRVADHIQSRIVYYLMNIHVTPRSIYLCRHGE 259
           +Y  LD D  D+DLS+IK+++VGQ ++VNRV D+IQS+IVYYLMNIHV PR+IYLCRHGE
Sbjct: 200 TYRPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIYLCRHGE 259

Query: 260 SELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVWTSQMKRTIQTAEALGVPYE 319
           SE NL G+IGGD GLS RG++FA++L +F+ +Q I DLKVWTSQ+KRTIQTAE+LGVPYE
Sbjct: 260 SEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTAESLGVPYE 319

Query: 320 QWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRYPKGESYEDLVQRLEPVIME 379
           QWK+LNEIDAGVCEEMTY EI+  YP EFALRDQ+KY YRYP GESY+DLVQRLEPVIME
Sbjct: 320 QWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIME 379

Query: 380 LERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTVLKLTPVAYGCKVESIFLNV 439
           LERQ NVLVI HQAVMRCLLAYFLDK A++LPYL+CPLHT+ KLTPVAYGCKVE+I LNV
Sbjct: 380 LERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNV 439

Query: 440 AAVNTHRDRPQNVD----ISRPPEEALVTVP 466
            AVNTHRD+P   +    + R P  A + +P
Sbjct: 440 EAVNTHRDKPTAAETTLAVRRRPSAASLMLP 470


>gi|64762406 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
           isoform a [Homo sapiens]
          Length = 505

 Score =  648 bits (1672), Expect = 0.0
 Identities = 310/432 (71%), Positives = 366/432 (84%), Gaps = 1/432 (0%)

Query: 21  NGRPALHACQRGVCMTNCPTLIVMVGLPARGKTYISKKLTRYLNWIGVPTREFNVGQYRR 80
           N R +   C     MTN PTLIVM+GLPARGKTY+SKKLTRYLNWIGVPT+ FN+G YRR
Sbjct: 20  NLRMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRR 79

Query: 81  DVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSEEGGHVAVFDATNTTRERRAT 140
           + VK+YKS++FF  DNEE +KIRKQCAL AL DV+ +L+EE G +AVFDATNTTRERR  
Sbjct: 80  EAVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDM 139

Query: 141 IFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYVNRDSDEATEDFMRRIECYEN 200
           I NF EQN +K FFVES+C DP+VIAANI++VK+ SPDY  R+ +   EDF++RIECY+ 
Sbjct: 140 ILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKV 199

Query: 201 SYESLDED-LDRDLSYIKIMDVGQSYVVNRVADHIQSRIVYYLMNIHVTPRSIYLCRHGE 259
           +Y  LD D  D+DLS+IK+++VGQ ++VNRV D+IQS+IVYYLMNIHV PR+IYLCRHGE
Sbjct: 200 TYRPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIYLCRHGE 259

Query: 260 SELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVWTSQMKRTIQTAEALGVPYE 319
           SE NL G+IGGD GLS RG++FA++L +F+ +Q I DLKVWTSQ+KRTIQTAE+LGVPYE
Sbjct: 260 SEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTAESLGVPYE 319

Query: 320 QWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRYPKGESYEDLVQRLEPVIME 379
           QWK+LNEIDAGVCEEMTY EI+  YP EFALRDQ+KY YRYP GESY+DLVQRLEPVIME
Sbjct: 320 QWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIME 379

Query: 380 LERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTVLKLTPVAYGCKVESIFLNV 439
           LERQ NVLVI HQAVMRCLLAYFLDK A++LPYL+CPLHT+ KLTPVAYGCKVE+I LNV
Sbjct: 380 LERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNV 439

Query: 440 AAVNTHRDRPQN 451
            AVNTHRD+P N
Sbjct: 440 EAVNTHRDKPTN 451


>gi|4505753 bisphosphoglycerate mutase 1 [Homo sapiens]
          Length = 254

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 31/79 (39%), Positives = 38/79 (48%), Gaps = 11/79 (13%)

Query: 252 IYLCRHGESELNLKGRIGG--DPGLSPRGREFAKSLAQFISDQNIKDLKVWTSQMKRTIQ 309
           + L RHGES  NL+ R  G  D  LSP G E AK   Q + D   +    +TS  KR I+
Sbjct: 6   LVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQKRAIR 65

Query: 310 TAEALGVPYEQWKVLNEID 328
           T          W VL+ ID
Sbjct: 66  TL---------WTVLDAID 75


>gi|71274132 bisphosphoglycerate mutase 4 [Homo sapiens]
          Length = 254

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 30/79 (37%), Positives = 36/79 (45%), Gaps = 11/79 (13%)

Query: 252 IYLCRHGESELNLKGRIGG--DPGLSPRGREFAKSLAQFISDQNIKDLKVWTSQMKRTIQ 309
           + L RHGES  NL+ R     D  LSP G E AK   Q + D   +     TS  KR I+
Sbjct: 6   LVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQKRVIR 65

Query: 310 TAEALGVPYEQWKVLNEID 328
           T          W VL+ ID
Sbjct: 66  TL---------WTVLDAID 75


>gi|50593010 bisphosphoglycerate mutase 2 [Homo sapiens]
          Length = 253

 Score = 37.7 bits (86), Expect = 0.023
 Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 2/65 (3%)

Query: 252 IYLCRHGESELNLKGRIGG--DPGLSPRGREFAKSLAQFISDQNIKDLKVWTSQMKRTIQ 309
           + + RHGES  N + R  G  D  LS +G E AK  A+ I D  ++    +TS +KR I+
Sbjct: 6   LVMVRHGESTWNQENRFCGWFDAELSEKGTEEAKRGAKAIKDAKMEFDICYTSVLKRAIR 65

Query: 310 TAEAL 314
           T  A+
Sbjct: 66  TLWAI 70


>gi|20070384 phosphoglycerate mutase family member 5 [Homo sapiens]
          Length = 255

 Score = 36.2 bits (82), Expect = 0.066
 Identities = 37/158 (23%), Positives = 67/158 (42%), Gaps = 25/158 (15%)

Query: 250 RSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVWTSQMKRTIQ 309
           R I+L RH  S+ ++ G +  D  L+P GRE A+     ++   +K  K+  S M R I+
Sbjct: 98  RHIFLIRH--SQYHVDGSLEKDRTLTPLGREQAELTGLRLASLGLKFNKIVHSSMTRAIE 155

Query: 310 TAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRYPKGESYEDL 369
           T +          +++    GVC+  T + +++  P+E          +  P+   Y + 
Sbjct: 156 TTD----------IISRHLPGVCKVST-DLLREGAPIE----PDPPVSHWKPEAVQYYED 200

Query: 370 VQRLEPVIMEL--------ERQENVLVICHQAVMRCLL 399
             R+E              E     + ICH  V+R ++
Sbjct: 201 GARIEAAFRNYIHRADARQEEDSYEIFICHANVIRYIV 238


>gi|94721261 2',3'-cyclic nucleotide 3' phosphodiesterase [Homo
           sapiens]
          Length = 421

 Score = 32.7 bits (73), Expect = 0.73
 Identities = 28/122 (22%), Positives = 47/122 (38%), Gaps = 18/122 (14%)

Query: 35  MTNCPTLIVMVGLPARGKTYISKKLTRYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLP 94
           +  C TL ++ GLP  GK+ +++ +               V +Y RD  K   +  + + 
Sbjct: 46  LLECKTLFILRGLPGSGKSTLARVI---------------VDKY-RDGTKMVSADAYKIT 89

Query: 95  DNEEGLKIRKQCALAALRDVRRFLSEEGGHVAVFDATNTTRERRATIFNFGEQNGYKTFF 154
               G    +   L    D+  +       + V D TN  RER   +F   +Q  Y+   
Sbjct: 90  PGARGAFSEEYKRLD--EDLAAYCRRRDIRILVLDDTNHERERLEQLFEMADQYQYQVVL 147

Query: 155 VE 156
           VE
Sbjct: 148 VE 149


>gi|31377775 glutamate dehydrogenase 2 [Homo sapiens]
          Length = 558

 Score = 32.3 bits (72), Expect = 0.95
 Identities = 28/128 (21%), Positives = 59/128 (46%), Gaps = 14/128 (10%)

Query: 311 AEALGVPYEQW-KVLNEIDAGVCEEMTYEEIQD-NYPLEFALRDQDKYRYRYPKGESYED 368
           A  + V Y +W K LN +  G    +T++  +D NY L  ++++  + ++    G     
Sbjct: 432 AGGVTVSYFEWLKNLNHVSYG---RLTFKYERDSNYHLLLSVQESLERKFGKHGGTI--- 485

Query: 369 LVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTVLKLTPVAY 428
                 P++   E Q+++     + ++   LAY ++++A Q+ +     +  L L   AY
Sbjct: 486 ------PIVPTAEFQDSISGASEKDIVHSALAYTMERSARQIMHTAMKYNLGLDLRTAAY 539

Query: 429 GCKVESIF 436
              +E +F
Sbjct: 540 VNAIEKVF 547


>gi|34452721 GA binding protein transcription factor, alpha subunit
           [Homo sapiens]
          Length = 454

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 33/119 (27%), Positives = 61/119 (51%), Gaps = 17/119 (14%)

Query: 289 ISDQNIKDLKVWTSQMKRTIQTAEALGVPYE--QW---KVLNEIDAGVCEEMTYEEIQDN 343
           ISD+  + +  W + ++   +  E LG+PY+  QW   +VL+ +   V +E +  +I D 
Sbjct: 155 ISDETSEQVTRWAAALEGYRKEQERLGIPYDPIQWSTDQVLHWV-VWVMKEFSMTDI-DL 212

Query: 344 YPLEFALRD-----QDKYRYRYPKGE---SYEDLVQRLEPVIMELERQENVLVICHQAV 394
             L  + R+     Q+ +  R P+GE   S+ +L+++   V+   E+Q N +V   Q V
Sbjct: 213 TTLNISGRELCSLNQEDFFQRVPRGEILWSHLELLRKY--VLASQEQQMNEIVTIDQPV 269


>gi|4559408 colony stimulating factor 2 receptor, beta precursor
           [Homo sapiens]
          Length = 897

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 17/69 (24%), Positives = 32/69 (46%), Gaps = 4/69 (5%)

Query: 276 PRGREFAKSLAQFISDQNIKDLKVWTSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEM 335
           P G     +L Q +     +DL++ T Q    +  + ALG P   W    +++     E+
Sbjct: 118 PLGTRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEF----EV 173

Query: 336 TYEEIQDNY 344
            Y+ +QD++
Sbjct: 174 VYKRLQDSW 182


>gi|4885281 glutamate dehydrogenase 1 [Homo sapiens]
          Length = 558

 Score = 29.3 bits (64), Expect = 8.0
 Identities = 28/128 (21%), Positives = 57/128 (44%), Gaps = 14/128 (10%)

Query: 311 AEALGVPYEQW-KVLNEIDAGVCEEMTYEEIQD-NYPLEFALRDQDKYRYRYPKGESYED 368
           A  + V Y +W K LN +  G    +T++  +D NY L  ++++  + ++    G     
Sbjct: 432 AGGVTVSYFEWLKNLNHVSYG---RLTFKYERDSNYHLLMSVQESLERKFGKHGGTI--- 485

Query: 369 LVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTVLKLTPVAY 428
                 P++   E Q+ +     + ++   LAY ++++A Q+       +  L L   AY
Sbjct: 486 ------PIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAY 539

Query: 429 GCKVESIF 436
              +E +F
Sbjct: 540 VNAIEKVF 547


>gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2
           [Homo sapiens]
          Length = 1235

 Score = 29.3 bits (64), Expect = 8.0
 Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 4/42 (9%)

Query: 168 NIVQVKLGSPDYVNRDSDEATEDFMRRIECYENSYESLDEDL 209
           +I++V++G+      +S +AT D   + E +E  Y SL EDL
Sbjct: 949 DIIEVEMGT----EAESTQATIDIYEKEEAFEIDYSSLKEDL 986


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,050,362
Number of Sequences: 37866
Number of extensions: 787588
Number of successful extensions: 1926
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1910
Number of HSP's gapped (non-prelim): 16
length of query: 469
length of database: 18,247,518
effective HSP length: 106
effective length of query: 363
effective length of database: 14,233,722
effective search space: 5166841086
effective search space used: 5166841086
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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