BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4758398 folate hydrolase 1 isoform 1 [Homo sapiens] (750 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4758398 folate hydrolase 1 isoform 1 [Homo sapiens] 1538 0.0 gi|62548858 folate hydrolase 1 isoform 2 [Homo sapiens] 1457 0.0 gi|4885505 N-acetylated alpha-linked acidic dipeptidase 2 [Homo ... 1075 0.0 gi|24308545 folate hydrolase 1B [Homo sapiens] 885 0.0 gi|57232740 N-acetylated alpha-linked acidic dipeptidase-like 1 ... 495 e-140 gi|33589848 transferrin receptor 2 [Homo sapiens] 259 8e-69 gi|189458819 transferrin receptor [Homo sapiens] 226 6e-59 gi|189458817 transferrin receptor [Homo sapiens] 226 6e-59 gi|126157508 N-acetylated alpha-linked acidic dipeptidase 2 [Hom... 212 9e-55 gi|239755481 PREDICTED: similar to Putative uncharacterized prot... 67 5e-11 gi|239744358 PREDICTED: hypothetical protein XP_002343105 [Homo ... 67 5e-11 gi|7706387 plasma glutamate carboxypeptidase [Homo sapiens] 50 8e-06 gi|65507403 SEC15-like 1 isoform a [Homo sapiens] 37 0.051 gi|62243652 SEC15-like 1 isoform b [Homo sapiens] 37 0.051 gi|51230412 GTPase activating Rap/RanGAP domain-like 1 isoform 2... 33 1.3 gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform 1... 33 1.3 gi|153945852 G7c protein [Homo sapiens] 32 1.7 gi|239752780 PREDICTED: hypothetical protein [Homo sapiens] 32 2.2 gi|239747286 PREDICTED: hypothetical protein XP_002346424 [Homo ... 32 2.2 gi|239741110 PREDICTED: hypothetical protein XP_002342097 [Homo ... 32 2.2 gi|23397672 homeobox D4 [Homo sapiens] 32 2.8 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 32 2.8 gi|110735404 protein tyrosine phosphatase, receptor type, U isof... 30 6.3 gi|110735406 protein tyrosine phosphatase, receptor type, U isof... 30 6.3 gi|110735402 protein tyrosine phosphatase, receptor type, U isof... 30 6.3 gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 30 6.3 gi|153266907 gamma-glutamyltransferase 5 isoform c [Homo sapiens] 30 8.2 gi|153266901 gamma-glutamyltransferase 5 isoform a [Homo sapiens] 30 8.2 gi|153266885 gamma-glutamyltransferase 5 isoform b [Homo sapiens] 30 8.2 >gi|4758398 folate hydrolase 1 isoform 1 [Homo sapiens] Length = 750 Score = 1538 bits (3983), Expect = 0.0 Identities = 750/750 (100%), Positives = 750/750 (100%) Query: 1 MWNLLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIKSSNEATNITPKHNMKA 60 MWNLLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIKSSNEATNITPKHNMKA Sbjct: 1 MWNLLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIKSSNEATNITPKHNMKA 60 Query: 61 FLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYP 120 FLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYP Sbjct: 61 FLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYP 120 Query: 121 NKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYA 180 NKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYA Sbjct: 121 NKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYA 180 Query: 181 RTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVK 240 RTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVK Sbjct: 181 RTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVK 240 Query: 241 SYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYY 300 SYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYY Sbjct: 241 SYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYY 300 Query: 301 DAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIG 360 DAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIG Sbjct: 301 DAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIG 360 Query: 361 TLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFAS 420 TLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFAS Sbjct: 361 TLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFAS 420 Query: 421 WDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKE 480 WDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKE Sbjct: 421 WDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKE 480 Query: 481 LKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKN 540 LKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKN Sbjct: 481 LKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKN 540 Query: 541 WETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDY 600 WETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDY Sbjct: 541 WETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDY 600 Query: 601 AVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIV 660 AVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIV Sbjct: 601 AVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIV 660 Query: 661 LRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVD 720 LRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVD Sbjct: 661 LRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVD 720 Query: 721 PSKAWGEVKRQIYVAAFTVQAAAETLSEVA 750 PSKAWGEVKRQIYVAAFTVQAAAETLSEVA Sbjct: 721 PSKAWGEVKRQIYVAAFTVQAAAETLSEVA 750 >gi|62548858 folate hydrolase 1 isoform 2 [Homo sapiens] Length = 719 Score = 1457 bits (3773), Expect = 0.0 Identities = 718/750 (95%), Positives = 719/750 (95%), Gaps = 31/750 (4%) Query: 1 MWNLLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIKSSNEATNITPKHNMKA 60 MWNLLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIKSSNEATNITPKHNMKA Sbjct: 1 MWNLLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIKSSNEATNITPKHNMKA 60 Query: 61 FLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYP 120 FLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYP Sbjct: 61 FLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYP 120 Query: 121 NKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYA 180 NKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYA Sbjct: 121 NKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYA 180 Query: 181 RTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVK 240 RTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVK Sbjct: 181 RTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVK 240 Query: 241 SYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYY 300 SYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYY Sbjct: 241 SYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYY 300 Query: 301 DAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIG 360 DAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIG Sbjct: 301 DAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIG 360 Query: 361 TLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFAS 420 TLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFAS Sbjct: 361 TLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFAS 420 Query: 421 WDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKE 480 WDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKE Sbjct: 421 WDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKE 480 Query: 481 LKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKN 540 LKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKN Sbjct: 481 LKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKN 540 Query: 541 WETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDY 600 WETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDY Sbjct: 541 WETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDY 600 Query: 601 AVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIV 660 AVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKS Sbjct: 601 AVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKS---- 656 Query: 661 LRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVD 720 +HVIYAPSSHNKYAGESFPGIYDALFDIESKVD Sbjct: 657 ---------------------------KHVIYAPSSHNKYAGESFPGIYDALFDIESKVD 689 Query: 721 PSKAWGEVKRQIYVAAFTVQAAAETLSEVA 750 PSKAWGEVKRQIYVAAFTVQAAAETLSEVA Sbjct: 690 PSKAWGEVKRQIYVAAFTVQAAAETLSEVA 719 >gi|4885505 N-acetylated alpha-linked acidic dipeptidase 2 [Homo sapiens] Length = 740 Score = 1075 bits (2781), Expect = 0.0 Identities = 508/732 (69%), Positives = 608/732 (83%), Gaps = 5/732 (0%) Query: 20 WLCAGALVLAGGFFLLGFLFGWFIKSSNEATNITPKHNMKAF--LDELKAENIKKFLYNF 77 W+C A + + FL+GF+ GWFIK E T H + + E+KAENIK FL +F Sbjct: 11 WMCLAAALAS---FLMGFMVGWFIKPLKETTTSVRYHQSIRWKLVSEMKAENIKSFLRSF 67 Query: 78 TQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNE 137 T++PHLAGTEQNF LAK+IQ+QWK+FGLDS +L HYDVLLSYPN+T+ NYISI++E E Sbjct: 68 TKLPHLAGTEQNFLLAKKIQTQWKKFGLDSAKLVHYDVLLSYPNETNANYISIVDEHETE 127 Query: 138 IFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCS 197 IF TS EPPP GYENV++IVPP++AFS QGMPEGDLVYVNYARTEDFFKLER+M INC+ Sbjct: 128 IFKTSYLEPPPDGYENVTNIVPPYNAFSAQGMPEGDLVYVNYARTEDFFKLEREMGINCT 187 Query: 198 GKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGN 257 GKIVIARYGK+FRGNKVKNA LAGA G+ILYSDPADYFAP V+ YP GWNLPG QRGN Sbjct: 188 GKIVIARYGKIFRGNKVKNAMLAGAIGIILYSDPADYFAPEVQPYPKGWNLPGTAAQRGN 247 Query: 258 ILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDS 317 +LNLNGAGDPLTPGYPA EY +R + E VG+P IPVHPIGY DA+ LL +GG APPD Sbjct: 248 VLNLNGAGDPLTPGYPAKEYTFRLDVEEGVGIPRIPVHPIGYNDAEILLRYLGGIAPPDK 307 Query: 318 SWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGH 377 SW+G+L V Y++GPGFTG+ S +KV+MH+++ N++TRIYNV+GT+RG+VEPDRYVILGGH Sbjct: 308 SWKGALNVSYSIGPGFTGSDSFRKVRMHVYNINKITRIYNVVGTIRGSVEPDRYVILGGH 367 Query: 378 RDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEE 437 RDSWVFG IDP SG AV+ EI RSFG L +GWRPRRTI+FASWDAEEFGLLGSTEWAEE Sbjct: 368 RDSWVFGAIDPTSGVAVLQEIARSFGKLMSKGWRPRRTIIFASWDAEEFGLLGSTEWAEE 427 Query: 438 NSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESW 497 N ++LQER +AYIN+DSSIEGNYTLRVDCTPL+Y LV+ LTKE+ SPD+GFE KSLYESW Sbjct: 428 NVKILQERSIAYINSDSSIEGNYTLRVDCTPLLYQLVYKLTKEIPSPDDGFESKSLYESW 487 Query: 498 TKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYE 557 +K PSPE +PRI+KLGSG+DFE +FQRLGIASGRARYTKN +T+K+S YP+YH++YE Sbjct: 488 LEKDPSPENKNLPRINKLGSGSDFEAYFQRLGIASGRARYTKNKKTDKYSSYPVYHTIYE 547 Query: 558 TYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMK 617 T+ELVEKFYDP FK L+VAQ+RG +V+EL +S ++PF+ +DYA L+ YA IY++S K Sbjct: 548 TFELVEKFYDPTFKKQLSVAQLRGALVYELVDSKIIPFNIQDYAEALKNYAASIYNLSKK 607 Query: 618 HPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQLMFLERAFID 677 H Q++ + VSFDSLFSAVKNF+E AS F +RL D +NPI +RMMNDQLM LERAFID Sbjct: 608 HDQQLTDHGVSFDSLFSAVKNFSEAASDFHKRLIQVDLNNPIAVRMMNDQLMLLERAFID 667 Query: 678 PLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAF 737 PLGLP + FYRH+I+APSSHNKYAGESFPGIYDA+FDIE+K + AW EVK+ I +AAF Sbjct: 668 PLGLPGKLFYRHIIFAPSSHNKYAGESFPGIYDAIFDIENKANSRLAWKEVKKHISIAAF 727 Query: 738 TVQAAAETLSEV 749 T+QAAA TL EV Sbjct: 728 TIQAAAGTLKEV 739 >gi|24308545 folate hydrolase 1B [Homo sapiens] Length = 442 Score = 885 bits (2288), Expect = 0.0 Identities = 433/442 (97%), Positives = 439/442 (99%) Query: 309 MGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEP 368 MGGSAPPDSSWRGSLKV YNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEP Sbjct: 1 MGGSAPPDSSWRGSLKVSYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEP 60 Query: 369 DRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGL 428 DRYVILGGHRDSWVFGGIDPQSGAAVVHE VRSFGTLKKEGWRPRRTILFASWDAEEFGL Sbjct: 61 DRYVILGGHRDSWVFGGIDPQSGAAVVHETVRSFGTLKKEGWRPRRTILFASWDAEEFGL 120 Query: 429 LGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGF 488 LGSTEWAE+NSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLV+NLTKELKSPDEGF Sbjct: 121 LGSTEWAEDNSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVYNLTKELKSPDEGF 180 Query: 489 EGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSG 548 EGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSG Sbjct: 181 EGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSG 240 Query: 549 YPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYA 608 YPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYA Sbjct: 241 YPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYA 300 Query: 609 DKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMMNDQL 668 DKIY+ISMKHPQEMKTYS+SFDSLFSAVKNFTEIASKFSERLQDFDKSNPI+LRMMNDQL Sbjct: 301 DKIYNISMKHPQEMKTYSLSFDSLFSAVKNFTEIASKFSERLQDFDKSNPILLRMMNDQL 360 Query: 669 MFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEV 728 MFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWG+V Sbjct: 361 MFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGDV 420 Query: 729 KRQIYVAAFTVQAAAETLSEVA 750 KRQI VAAFTVQAAAETLSEVA Sbjct: 421 KRQISVAAFTVQAAAETLSEVA 442 >gi|57232740 N-acetylated alpha-linked acidic dipeptidase-like 1 [Homo sapiens] Length = 740 Score = 495 bits (1274), Expect = e-140 Identities = 286/743 (38%), Positives = 426/743 (57%), Gaps = 32/743 (4%) Query: 24 GALVLAGGFFLLGFLFGWFI---KSSNEATNITPKHNMKAFLDELKAENIKKFLYNFTQI 80 GA L G LG + G F K+++ A ++ + +L A I++ L ++ Sbjct: 12 GAAALLG----LGIILGHFAIPKKANSLAPQDLDLEILETVMGQLDAHRIRENLRELSRE 67 Query: 81 PHLAGTEQNFQLAKQIQSQWK--EFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEI 138 PHLA + ++ L + + +WK E GLDS E + Y+VLLS+P++ PN + I+ G I Sbjct: 68 PHLASSPRDEDLVQLLLQRWKDPESGLDSAEASTYEVLLSFPSQEQPNVVDIVGPTGGII 127 Query: 139 FNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSG 198 + E G + D+V P++A++P G P+G LVY N EDF +L+ I G Sbjct: 128 HSCHRTEENVTGEQGGPDVVQPYAAYAPSGTPQGLLVYANRGAEEDFKELQTQ-GIKLEG 186 Query: 199 KIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADY---FAPGVKSYPDGWNLPGGGVQR 255 I + RYG V RG K NA G GV++Y+DPAD + +++P+ W LP GV+R Sbjct: 187 TIALTRYGGVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFPNSWYLPPSGVER 246 Query: 256 GNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPP 315 G+ GDPLTP PA ++R +A G P IP PIG+ DA+ LL + G+ P Sbjct: 247 GSYYEY--FGDPLTPYLPAVPSSFRVDLANVSGFPPIPTQPIGFQDARDLLCNLNGTLAP 304 Query: 316 DSSWRGSLKVPYNVGPGFT--GNF-STQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYV 372 ++W+G+L Y +GPGF G+F + +V + +++ E+ NV+G +RGAVEPDRYV Sbjct: 305 -ATWQGALGCHYRLGPGFRPDGDFPADSQVNVSVYNRLELRNSSNVLGIIRGAVEPDRYV 363 Query: 373 ILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEG-WRPRRTILFASWDAEEFGLLGS 431 + G HRDSWV G +DP SG AV+ E+ R GTL K+G WRPRR+I+FASW AEEFGL+GS Sbjct: 364 LYGNHRDSWVHGAVDPSSGTAVLLELSRVLGTLLKKGTWRPRRSIVFASWGAEEFGLIGS 423 Query: 432 TEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGK 491 TE+ EE LQER VAYIN D S+ N TLRV TP + S+V + TKE++SP G Sbjct: 424 TEFTEEFFNKLQERTVAYINVDISVFANATLRVQGTPPVQSVVFSATKEIRSPGPG--DL 481 Query: 492 SLYESWTK--KSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGY 549 S+Y++W + SP + +P + LG+G+D+ F LGI+S YT + Y Sbjct: 482 SIYDNWIRYFNRSSPVYGLVPSLGSLGAGSDYAPFVHFLGISSMDIAYTYDRSKTSARIY 541 Query: 550 PLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYAD 609 P YH+ ++T++ V+KF DP F H VA+ G ++ L++S LP DY+ LR + Sbjct: 542 PTYHTAFDTFDYVDKFLDPGFSSHQAVARTAGSVILRLSDSFFLPLKVSDYSETLRSF-- 599 Query: 610 KIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKS--NPIVLRMMNDQ 667 + + ++ +S+S L +AV+ F A+ +R+ K +P+ +RM+NDQ Sbjct: 600 -LQAAQQDLGALLEQHSISLGPLVTAVEKFEAEAAALGQRISTLQKGSPDPLQVRMLNDQ 658 Query: 668 LMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGE 727 LM LER F++P P+ +Y HV++AP + + +FPG+ +A S+AW E Sbjct: 659 LMLLERTFLNPRAFPEERYYSHVLWAPRTGSVV---TFPGLSNACSRARDTASGSEAWAE 715 Query: 728 VKRQIYVAAFTVQAAAETLSEVA 750 V+RQ+ + ++ AA TL VA Sbjct: 716 VQRQLSIVVTALEGAAATLRPVA 738 >gi|33589848 transferrin receptor 2 [Homo sapiens] Length = 801 Score = 259 bits (661), Expect = 8e-69 Identities = 208/769 (27%), Positives = 352/769 (45%), Gaps = 84/769 (10%) Query: 11 AVATARRPRWLCAGALVLAGGFFLLGFLF--------GWFIKSSNEATNITPK---HNMK 59 A A R +L AL++ G FLLG++ G + +E N P H + Sbjct: 75 AAAGRRAAPYLVLTALLIFTGAFLLGYVAFRGSCQACGDSVLVVSEDVNYEPDLDFHQGR 134 Query: 60 AFLDELKAE--------NIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELA 111 + +L+A ++ + + +AG+ L + I++ LD V Sbjct: 135 LYWSDLQAMFLQFLGEGRLEDTIRQTSLRERVAGSAGMAALTQDIRAALSRQKLDHVWTD 194 Query: 112 HYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPE 171 + V L +P+ HPN + ++E G L +P D+ P+SA G Sbjct: 195 THYVGLQFPDPAHPNTLHWVDEAGKVGEQLPLEDP---------DVYCPYSAI---GNVT 242 Query: 172 GDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDP 231 G+LVY +Y R ED L R ++ G++++ R G + KV NAQ GA+GV++Y +P Sbjct: 243 GELVYAHYGRPEDLQDL-RARGVDPVGRLLLVRVGVISFAQKVTNAQDFGAQGVLIYPEP 301 Query: 232 ADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPS 291 AD+ K G V G GDP TPG+P+ +A + GLPS Sbjct: 302 ADFSQDPPKPSLSSQQAVYGHVHLGT-------GDPYTPGFPSFNQTQFPPVASS-GLPS 353 Query: 292 IPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLK-VPYNVGPGFTGNFSTQKVKMHIHSTN 350 IP PI A +LL K+ G P W+GSL PY++GPG ++++ +++ Sbjct: 354 IPAQPISADIASRLLRKLKGPVAPQE-WQGSLLGSPYHLGPG-------PRLRLVVNNHR 405 Query: 351 EVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGW 410 T I N+ G + G EPD YV++G RD+W G G A++ E+VR+F ++ G+ Sbjct: 406 TSTPINNIFGCIEGRSEPDHYVVIGAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSNGF 465 Query: 411 RPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLM 470 RPRR++LF SWD +FG +GSTEW E +L + V Y++ D+++ G+ +PL+ Sbjct: 466 RPRRSLLFISWDGGDFGSVGSTEWLEGYLSVLHLKAVVYVSLDNAVLGDDKFHAKTSPLL 525 Query: 471 YSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGI 530 SL+ ++ K++ SP+ G++LYE +PS + + + S F F +G+ Sbjct: 526 TSLIESVLKQVDSPNH--SGQTLYEQVVFTNPSWDAEVIRPLPMDSSAYSFTAF---VGV 580 Query: 531 ASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMF-KYHLTVAQVRGGMVFELAN 589 + + ++ + YP H+ +TYE + K VAQ+ G ++ L++ Sbjct: 581 PAVEFSFMEDDQ-----AYPFLHTKEDTYENLHKVLQGRLPAVAQAVAQLAGQLLIRLSH 635 Query: 590 SIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSER 649 +LP D Y V+ ++ + S ++K ++ ++SA ++ A K + Sbjct: 636 DRLLPLDFGRYGDVVLRHIGNLNEFS----GDLKARGLTLQWVYSARGDYIRAAEKLRQE 691 Query: 650 LQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYA-------- 701 + ++ + + RM N ++M +E F+ P +RH+ H A Sbjct: 692 IYSSEERDERLTRMYNVRIMRVEFYFLSQYVSPADSPFRHIFMGRGDHTLGALLDHLRLL 751 Query: 702 ---GESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLS 747 PG + ES+ +RQ+ + +T+Q AA LS Sbjct: 752 RSNSSGTPGATSSTGFQESR---------FRRQLALLTWTLQGAANALS 791 >gi|189458819 transferrin receptor [Homo sapiens] Length = 760 Score = 226 bits (576), Expect = 6e-59 Identities = 182/700 (26%), Positives = 323/700 (46%), Gaps = 84/700 (12%) Query: 55 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYD 114 K + LD K L + +P AG++++ LA +++Q++EF L V + Sbjct: 128 KRKLSEKLDSTDFTGTIKLLNENSYVPREAGSQKDENLALYVENQFREFKLSKVWRDQHF 187 Query: 115 VLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDL 174 V + + N + I++++G ++ P GY A+S G L Sbjct: 188 VKIQVKDSAQ-NSVIIVDKNGRLVYLVE----NPGGYV----------AYSKAATVTGKL 232 Query: 175 VYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADY 234 V+ N+ +DF D+ +G IVI R GK+ KV NA+ A GV++Y D + Sbjct: 233 VHANFGTKKDF----EDLYTPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDQTKF 288 Query: 235 FAPGVK-SYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIP 293 + S+ +L G GDP TPG+P+ + + + + GLP+IP Sbjct: 289 PIVNAELSFFGHAHL--------------GTGDPYTPGFPSFNHT-QFPPSRSSGLPNIP 333 Query: 294 VHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVT 353 V I A+KL M G P D + ++ + ++ VK+ + + + Sbjct: 334 VQTISRAAAEKLFGNMEGDCPSDWKTDSTCRMVTS---------ESKNVKLTVSNVLKEI 384 Query: 354 RIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLK-KEGWRP 412 +I N+ G ++G VEPD YV++G RD+W G G A++ ++ + F + K+G++P Sbjct: 385 KILNIFGVIKGFVEPDHYVVVGAQRDAWGPGAAKSGVGTALLLKLAQMFSDMVLKDGFQP 444 Query: 413 RRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYS 472 R+I+FASW A +FG +G+TEW E L + YIN D ++ G +V +PL+Y+ Sbjct: 445 SRSIIFASWSAGDFGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYT 504 Query: 473 LVHNLTKELKSPDEGFEGKSLYE--SWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGI 530 L+ + +K P G+ LY+ +W K + KL N F GI Sbjct: 505 LIEKTMQNVKHP---VTGQFLYQDSNWASK-----------VEKLTLDNAAFPFLAYSGI 550 Query: 531 ASGRARYTKNWETNKFSGYPLYHSVYETY-ELVEKFYDPMFKYHLTVAQVRGGMVFELAN 589 + + ++ + YP + +TY EL+E+ + + K A+V G V +L + Sbjct: 551 PAVSFCFCED------TDYPYLGTTMDTYKELIERIPE-LNKVARAAAEVAGQFVIKLTH 603 Query: 590 SIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSER 649 + L D Y L + + ++ ++K +S L+SA +F S+ + Sbjct: 604 DVELNLDYERYNSQLLSFVRDL----NQYRADIKEMGLSLQWLYSARGDFFRATSRLTTD 659 Query: 650 LQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIY 709 + +K++ V++ +ND++M +E F+ P P +RHV + SH + P + Sbjct: 660 FGNAEKTDRFVMKKLNDRVMRVEYHFLSPYVSPKESPFRHVFWGSGSH------TLPAL- 712 Query: 710 DALFDIESKVDPSKAWGEV--KRQIYVAAFTVQAAAETLS 747 L +++ + + A+ E + Q+ +A +T+Q AA LS Sbjct: 713 --LENLKLRKQNNGAFNETLFRNQLALATWTIQGAANALS 750 >gi|189458817 transferrin receptor [Homo sapiens] Length = 760 Score = 226 bits (576), Expect = 6e-59 Identities = 182/700 (26%), Positives = 323/700 (46%), Gaps = 84/700 (12%) Query: 55 KHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYD 114 K + LD K L + +P AG++++ LA +++Q++EF L V + Sbjct: 128 KRKLSEKLDSTDFTGTIKLLNENSYVPREAGSQKDENLALYVENQFREFKLSKVWRDQHF 187 Query: 115 VLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDL 174 V + + N + I++++G ++ P GY A+S G L Sbjct: 188 VKIQVKDSAQ-NSVIIVDKNGRLVYLVE----NPGGYV----------AYSKAATVTGKL 232 Query: 175 VYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADY 234 V+ N+ +DF D+ +G IVI R GK+ KV NA+ A GV++Y D + Sbjct: 233 VHANFGTKKDF----EDLYTPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDQTKF 288 Query: 235 FAPGVK-SYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIP 293 + S+ +L G GDP TPG+P+ + + + + GLP+IP Sbjct: 289 PIVNAELSFFGHAHL--------------GTGDPYTPGFPSFNHT-QFPPSRSSGLPNIP 333 Query: 294 VHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVT 353 V I A+KL M G P D + ++ + ++ VK+ + + + Sbjct: 334 VQTISRAAAEKLFGNMEGDCPSDWKTDSTCRMVTS---------ESKNVKLTVSNVLKEI 384 Query: 354 RIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLK-KEGWRP 412 +I N+ G ++G VEPD YV++G RD+W G G A++ ++ + F + K+G++P Sbjct: 385 KILNIFGVIKGFVEPDHYVVVGAQRDAWGPGAAKSGVGTALLLKLAQMFSDMVLKDGFQP 444 Query: 413 RRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYS 472 R+I+FASW A +FG +G+TEW E L + YIN D ++ G +V +PL+Y+ Sbjct: 445 SRSIIFASWSAGDFGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYT 504 Query: 473 LVHNLTKELKSPDEGFEGKSLYE--SWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGI 530 L+ + +K P G+ LY+ +W K + KL N F GI Sbjct: 505 LIEKTMQNVKHP---VTGQFLYQDSNWASK-----------VEKLTLDNAAFPFLAYSGI 550 Query: 531 ASGRARYTKNWETNKFSGYPLYHSVYETY-ELVEKFYDPMFKYHLTVAQVRGGMVFELAN 589 + + ++ + YP + +TY EL+E+ + + K A+V G V +L + Sbjct: 551 PAVSFCFCED------TDYPYLGTTMDTYKELIERIPE-LNKVARAAAEVAGQFVIKLTH 603 Query: 590 SIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSER 649 + L D Y L + + ++ ++K +S L+SA +F S+ + Sbjct: 604 DVELNLDYERYNSQLLSFVRDL----NQYRADIKEMGLSLQWLYSARGDFFRATSRLTTD 659 Query: 650 LQDFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIY 709 + +K++ V++ +ND++M +E F+ P P +RHV + SH + P + Sbjct: 660 FGNAEKTDRFVMKKLNDRVMRVEYHFLSPYVSPKESPFRHVFWGSGSH------TLPAL- 712 Query: 710 DALFDIESKVDPSKAWGEV--KRQIYVAAFTVQAAAETLS 747 L +++ + + A+ E + Q+ +A +T+Q AA LS Sbjct: 713 --LENLKLRKQNNGAFNETLFRNQLALATWTIQGAANALS 750 >gi|126157508 N-acetylated alpha-linked acidic dipeptidase 2 [Homo sapiens] Length = 795 Score = 212 bits (540), Expect = 9e-55 Identities = 185/702 (26%), Positives = 319/702 (45%), Gaps = 87/702 (12%) Query: 4 LLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIK----SSNEATNITPKHNMK 59 + H T SA + R L A F+ G L G+++ S ++ + Sbjct: 107 ITHYTRSAPKSNRCNFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQ 166 Query: 60 AFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSY 119 L ++AE+IKK N Q L E + +++K+I++QW GL+ V+ +Y VLL Sbjct: 167 EILKTIQAEDIKKSFRNLVQ---LYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDL 223 Query: 120 PNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVS-DIVPPFSAFSPQGMPEGDLVYVN 178 P P+ ++ + F+ + ++ S D++ ++A+S +G + +++ V+ Sbjct: 224 PG---PSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQDLLYSYAAYSAKGTLKAEVIDVS 280 Query: 179 YARTEDFFKLERDMKI-NCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAP 237 Y +D L+R KI N + +I + + GK+ K+ + + AG GV+LY DP D Sbjct: 281 YGMADD---LKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCD-LPK 336 Query: 238 GVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPI 297 V D + +++LN GDP TPGYP+ + ++R+ + L S+ V PI Sbjct: 337 TVNPSHDTF-----------MVSLNPGGDPSTPGYPSVDESFRQSRSN---LTSLLVQPI 382 Query: 298 GYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYN 357 KL+ ++ SL++P N + V M + + ++ + N Sbjct: 383 SAPLVAKLISSPKARTKNEAC--SSLELPNN---------EIRVVSMQVQTVTKLKTVTN 431 Query: 358 VIGTLRGAVEPDRYVILGGHRDS-WVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTI 416 V+G + G PDRY+I+G H + + G + S A++ +R+ + K GWRP RTI Sbjct: 432 VVGFVMGLTSPDRYIIVGSHHHTAHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTI 491 Query: 417 LFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHN 476 +F SW FG +GS EW E+ ++LQ+ VAYI+ S I GN +L +P + LV Sbjct: 492 VFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPVASPSLQQLVVE 551 Query: 477 LTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRAR 536 + T+++ PE IS + D + F LG+ + Sbjct: 552 KNN---------------FNCTRRAQCPE----TNISSIQIQGDADYFINHLGVPIVQFA 592 Query: 537 Y--TKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLP 594 Y K E F L + + T + DP F H T+ ++ G ++ ++AN VLP Sbjct: 593 YEDIKTLEGPSF----LSEARFSTRATKIEEMDPSFNLHETITKLSGEVILQIANEPVLP 648 Query: 595 FDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKF-SERLQ-- 651 F+ D I+++ +K + L + E A F S+ ++ Sbjct: 649 FNALD--------------IALEVQNNLKGDQPNTHQLLAMALRLRESAELFQSDEMRPA 694 Query: 652 -DFDKSNPIVLRMMNDQLMFLERAFIDPLGLPDRPFYRHVIY 692 D + PI +RM+ND L +E++F+ P FYR+++Y Sbjct: 695 NDPKERAPIRIRMLNDILQDMEKSFLVKQAPPG--FYRNILY 734 >gi|239755481 PREDICTED: similar to Putative uncharacterized protein ENSP00000334305 [Homo sapiens] Length = 771 Score = 67.4 bits (163), Expect = 5e-11 Identities = 31/44 (70%), Positives = 37/44 (84%) Query: 264 AGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLE 307 + +P + ++EYAYR GIAEAVGLPSIPVHPIGYYDA+KLLE Sbjct: 462 SSNPNQDDFHSSEYAYRCGIAEAVGLPSIPVHPIGYYDAEKLLE 505 >gi|239744358 PREDICTED: hypothetical protein XP_002343105 [Homo sapiens] Length = 767 Score = 67.4 bits (163), Expect = 5e-11 Identities = 31/44 (70%), Positives = 37/44 (84%) Query: 264 AGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLE 307 + +P + ++EYAYR GIAEAVGLPSIPVHPIGYYDA+KLLE Sbjct: 458 SSNPNQDDFHSSEYAYRCGIAEAVGLPSIPVHPIGYYDAEKLLE 501 >gi|7706387 plasma glutamate carboxypeptidase [Homo sapiens] Length = 472 Score = 50.1 bits (118), Expect = 8e-06 Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 5/84 (5%) Query: 353 TRIYNVIGTLRGAVEPDRYVILGGHRDSWVF--GGIDPQSGAAVVHEIVRSFGTLKKEGW 410 T +N + + G+ P++ V++ GH DSW G +D GA + E + +K G Sbjct: 266 TDSFNTVAEITGSKYPEQVVLVSGHLDSWDVGQGAMDDGGGAFISWE---ALSLIKDLGL 322 Query: 411 RPRRTILFASWDAEEFGLLGSTEW 434 RP+RT+ W AEE G +G+ ++ Sbjct: 323 RPKRTLRLVLWTAEEQGGVGAFQY 346 >gi|65507403 SEC15-like 1 isoform a [Homo sapiens] Length = 804 Score = 37.4 bits (85), Expect = 0.051 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 1/78 (1%) Query: 552 YHSVYETYELVEKFYDP-MFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADK 610 Y+S +T E +E Y P + +Y + + D +D+ +RK++DK Sbjct: 154 YYSALKTMEQLENVYFPWVSQYRFCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSDK 213 Query: 611 IYSISMKHPQEMKTYSVS 628 I +MK Q KT+SVS Sbjct: 214 IGETAMKQAQHQKTFSVS 231 >gi|62243652 SEC15-like 1 isoform b [Homo sapiens] Length = 799 Score = 37.4 bits (85), Expect = 0.051 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 1/78 (1%) Query: 552 YHSVYETYELVEKFYDP-MFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADK 610 Y+S +T E +E Y P + +Y + + D +D+ +RK++DK Sbjct: 149 YYSALKTMEQLENVYFPWVSQYRFCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSDK 208 Query: 611 IYSISMKHPQEMKTYSVS 628 I +MK Q KT+SVS Sbjct: 209 IGETAMKQAQHQKTFSVS 226 >gi|51230412 GTPase activating Rap/RanGAP domain-like 1 isoform 2 [Homo sapiens] Length = 2083 Score = 32.7 bits (73), Expect = 1.3 Identities = 16/43 (37%), Positives = 21/43 (48%) Query: 120 PNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFS 162 P T + S E GNE+F E P P + SDI+ PF+ Sbjct: 764 PRSTRVRHFSQSEETGNEVFGALNEEQPLPRSSSTSDILEPFT 806 >gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform 1 [Homo sapiens] Length = 2036 Score = 32.7 bits (73), Expect = 1.3 Identities = 16/43 (37%), Positives = 21/43 (48%) Query: 120 PNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFS 162 P T + S E GNE+F E P P + SDI+ PF+ Sbjct: 764 PRSTRVRHFSQSEETGNEVFGALNEEQPLPRSSSTSDILEPFT 806 >gi|153945852 G7c protein [Homo sapiens] Length = 891 Score = 32.3 bits (72), Expect = 1.7 Identities = 15/52 (28%), Positives = 26/52 (50%), Gaps = 2/52 (3%) Query: 249 PGGGVQRGNILNLNGAGDPLTPGYPANEYAY--RRGIAEAVGLPSIPVHPIG 298 P G+Q ++ + G G PG P +++ RG+ E L +P+ P+G Sbjct: 625 PVAGLQTQLLVEVTGLGSRANPGDPQPHFSHVILRGVPEGAELGQVPLEPVG 676 >gi|239752780 PREDICTED: hypothetical protein [Homo sapiens] Length = 290 Score = 32.0 bits (71), Expect = 2.2 Identities = 25/74 (33%), Positives = 33/74 (44%), Gaps = 4/74 (5%) Query: 321 GSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDS 380 GS K P +GP TG + ++ + S V R +G GAV P V+L G S Sbjct: 46 GSSKSP--LGPPLTGTSGSSRIVVRKVSGVGVCREATSVGP--GAVVPRGRVLLSGMSGS 101 Query: 381 WVFGGIDPQSGAAV 394 WV G+ G V Sbjct: 102 WVVAGLGRALGREV 115 >gi|239747286 PREDICTED: hypothetical protein XP_002346424 [Homo sapiens] Length = 290 Score = 32.0 bits (71), Expect = 2.2 Identities = 25/74 (33%), Positives = 33/74 (44%), Gaps = 4/74 (5%) Query: 321 GSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDS 380 GS K P +GP TG + ++ + S V R +G GAV P V+L G S Sbjct: 46 GSSKSP--LGPPLTGTSGSSRIVVRKVSGVGVCREATSVGP--GAVVPRGRVLLSGMSGS 101 Query: 381 WVFGGIDPQSGAAV 394 WV G+ G V Sbjct: 102 WVVAGLGRALGREV 115 >gi|239741110 PREDICTED: hypothetical protein XP_002342097 [Homo sapiens] Length = 290 Score = 32.0 bits (71), Expect = 2.2 Identities = 25/74 (33%), Positives = 33/74 (44%), Gaps = 4/74 (5%) Query: 321 GSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDS 380 GS K P +GP TG + ++ + S V R +G GAV P V+L G S Sbjct: 46 GSSKSP--LGPPLTGTSGSSRIVVRKVSGVGVCREATSVGP--GAVVPRGRVLLSGMSGS 101 Query: 381 WVFGGIDPQSGAAV 394 WV G+ G V Sbjct: 102 WVVAGLGRALGREV 115 >gi|23397672 homeobox D4 [Homo sapiens] Length = 255 Score = 31.6 bits (70), Expect = 2.8 Identities = 32/119 (26%), Positives = 42/119 (35%), Gaps = 16/119 (13%) Query: 232 ADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPS 291 AD+ PG+ PD P GG G L G PG P YA A P+ Sbjct: 44 ADFQPPGLYPRPDFGEQPFGGSGPGPGSALPARGHGQEPGGPGGHYA-----APGEPCPA 98 Query: 292 IPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTN 350 P P + + PP + +LK P V P K+H++S N Sbjct: 99 PPAPPPAPLPGARAYSQSDPKQPPSGT---ALKQPAVVYPWMK--------KVHVNSVN 146 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 31.6 bits (70), Expect = 2.8 Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 5/57 (8%) Query: 237 PGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIP 293 PG+ YP PGG Q G++ AG PG P R G GLP IP Sbjct: 839 PGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPG-----RPGAHGPPGLPGIP 890 >gi|110735404 protein tyrosine phosphatase, receptor type, U isoform 1 precursor [Homo sapiens] Length = 1436 Score = 30.4 bits (67), Expect = 6.3 Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 5/72 (6%) Query: 293 PVHPIGYYDAQKL--LEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTN 350 P H + Y+ L + ++ S PPD+ G + + + G G TG + V + + Sbjct: 1042 PEHGVPYHATGLLAFIRRVKASTPPDA---GPIVIHCSAGTGRTGCYIVLDVMLDMAECE 1098 Query: 351 EVTRIYNVIGTL 362 V IYN + TL Sbjct: 1099 GVVDIYNCVKTL 1110 >gi|110735406 protein tyrosine phosphatase, receptor type, U isoform 2 precursor [Homo sapiens] Length = 1442 Score = 30.4 bits (67), Expect = 6.3 Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 5/72 (6%) Query: 293 PVHPIGYYDAQKL--LEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTN 350 P H + Y+ L + ++ S PPD+ G + + + G G TG + V + + Sbjct: 1048 PEHGVPYHATGLLAFIRRVKASTPPDA---GPIVIHCSAGTGRTGCYIVLDVMLDMAECE 1104 Query: 351 EVTRIYNVIGTL 362 V IYN + TL Sbjct: 1105 GVVDIYNCVKTL 1116 >gi|110735402 protein tyrosine phosphatase, receptor type, U isoform 3 precursor [Homo sapiens] Length = 1446 Score = 30.4 bits (67), Expect = 6.3 Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 5/72 (6%) Query: 293 PVHPIGYYDAQKL--LEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTN 350 P H + Y+ L + ++ S PPD+ G + + + G G TG + V + + Sbjct: 1052 PEHGVPYHATGLLAFIRRVKASTPPDA---GPIVIHCSAGTGRTGCYIVLDVMLDMAECE 1108 Query: 351 EVTRIYNVIGTL 362 V IYN + TL Sbjct: 1109 GVVDIYNCVKTL 1120 >gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] Length = 698 Score = 30.4 bits (67), Expect = 6.3 Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 15/127 (11%) Query: 243 PDGWNLPGGGVQ-----RGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPI 297 P+G P GG+Q + + G+P PG PA+ + G A AV + P P Sbjct: 354 PEGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGPG 413 Query: 298 GYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYN 357 K ++ + SW+ S + P ++ G S+ +V + N + N Sbjct: 414 SRCSPGKKVQTL-------PSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGN---WLMN 463 Query: 358 VIGTLRG 364 + +LRG Sbjct: 464 GLSSLRG 470 >gi|153266907 gamma-glutamyltransferase 5 isoform c [Homo sapiens] Length = 554 Score = 30.0 bits (66), Expect = 8.2 Identities = 11/39 (28%), Positives = 24/39 (61%) Query: 109 ELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPP 147 +L+HY + ++ + T +++S++ EDG+ + TS P Sbjct: 340 QLSHYSLAEAWGHGTGTSHVSVLGEDGSAVAATSTINTP 378 >gi|153266901 gamma-glutamyltransferase 5 isoform a [Homo sapiens] Length = 587 Score = 30.0 bits (66), Expect = 8.2 Identities = 11/39 (28%), Positives = 24/39 (61%) Query: 109 ELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPP 147 +L+HY + ++ + T +++S++ EDG+ + TS P Sbjct: 372 QLSHYSLAEAWGHGTGTSHVSVLGEDGSAVAATSTINTP 410 >gi|153266885 gamma-glutamyltransferase 5 isoform b [Homo sapiens] Length = 586 Score = 30.0 bits (66), Expect = 8.2 Identities = 11/39 (28%), Positives = 24/39 (61%) Query: 109 ELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPP 147 +L+HY + ++ + T +++S++ EDG+ + TS P Sbjct: 372 QLSHYSLAEAWGHGTGTSHVSVLGEDGSAVAATSTINTP 410 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.137 0.418 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 30,581,536 Number of Sequences: 37866 Number of extensions: 1515436 Number of successful extensions: 3285 Number of sequences better than 10.0: 29 Number of HSP's better than 10.0 without gapping: 19 Number of HSP's successfully gapped in prelim test: 10 Number of HSP's that attempted gapping in prelim test: 3214 Number of HSP's gapped (non-prelim): 39 length of query: 750 length of database: 18,247,518 effective HSP length: 110 effective length of query: 640 effective length of database: 14,082,258 effective search space: 9012645120 effective search space used: 9012645120 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.