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Search of human proteins with 4757748
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]
(454 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens] 912 0.0
gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens] 891 0.0
gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens] 874 0.0
gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens] 856 0.0
gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens] 853 0.0
gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens] 840 0.0
gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens] 802 0.0
gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens] 796 0.0
gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens] 769 0.0
gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens] 585 e-167
gi|21536423 amphiphysin isoform 2 [Homo sapiens] 357 9e-99
gi|4502081 amphiphysin isoform 1 [Homo sapiens] 357 9e-99
gi|49472835 bridging integrator 2 [Homo sapiens] 308 9e-84
gi|8923904 bridging integrator 3 [Homo sapiens] 57 3e-08
gi|39930351 dynamin binding protein [Homo sapiens] 49 7e-06
gi|49640014 ubiquitin associated and SH3 domain containing, A sh... 46 6e-05
gi|9507221 ubiquitin associated and SH3 domain containing, A lon... 46 6e-05
gi|4826964 UV excision repair protein RAD23 homolog A [Homo sapi... 45 1e-04
gi|115527120 nebulin [Homo sapiens] 44 2e-04
gi|110832843 TBP-associated factor 4 [Homo sapiens] 44 3e-04
gi|40807452 peroxisome proliferator-activated receptor gamma, co... 42 9e-04
gi|7662162 ALEX2 protein [Homo sapiens] 42 9e-04
gi|29540562 ALEX2 protein [Homo sapiens] 42 9e-04
gi|219842343 glutamate receptor, metabotropic 5 isoform a precur... 42 0.001
gi|4504143 glutamate receptor, metabotropic 5 isoform b precurso... 42 0.001
gi|241982780 programmed cell death 6 interacting protein isoform... 42 0.001
gi|22027538 programmed cell death 6 interacting protein isoform ... 42 0.001
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 42 0.001
gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo ... 41 0.003
gi|239749199 PREDICTED: hypothetical protein XP_002346952 [Homo ... 41 0.003
>gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]
Length = 454
Score = 912 bits (2357), Expect = 0.0
Identities = 454/454 (100%), Positives = 454/454 (100%)
Query: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
Query: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
Query: 301 EPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 360
EPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP
Sbjct: 301 EPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 360
Query: 361 ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD 420
ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD
Sbjct: 361 ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD 420
Query: 421 EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 454
EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 421 EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 454
>gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]
Length = 497
Score = 891 bits (2303), Expect = 0.0
Identities = 454/497 (91%), Positives = 454/497 (91%), Gaps = 43/497 (8%)
Query: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
Query: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
Query: 301 EPAGGATPGATLPKS-------------------------------------------PS 317
EPAGGATPGATLPKS PS
Sbjct: 301 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 360
Query: 318 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 377
QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD
Sbjct: 361 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 420
Query: 378 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 437
LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE
Sbjct: 421 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 480
Query: 438 LEKCRGVFPENFTERVP 454
LEKCRGVFPENFTERVP
Sbjct: 481 LEKCRGVFPENFTERVP 497
>gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]
Length = 439
Score = 874 bits (2258), Expect = 0.0
Identities = 439/454 (96%), Positives = 439/454 (96%), Gaps = 15/454 (3%)
Query: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
Query: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
KQHGSNTFTVKAQP SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 285
Query: 301 EPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 360
EPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP
Sbjct: 286 EPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 345
Query: 361 ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD 420
ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD
Sbjct: 346 ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD 405
Query: 421 EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 454
EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 406 EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 439
>gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]
Length = 475
Score = 856 bits (2211), Expect = 0.0
Identities = 439/490 (89%), Positives = 439/490 (89%), Gaps = 51/490 (10%)
Query: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
Query: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
KQHGSNTFTVKAQP SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 285
Query: 301 EPAGGATPGATLPKSPS------------------------------------QPAEASE 324
EPAGGATPGATLPKSPS QPAEASE
Sbjct: 286 EPAGGATPGATLPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASE 345
Query: 325 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF 384
VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF
Sbjct: 346 VAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMF 405
Query: 385 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 444
KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV
Sbjct: 406 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGV 465
Query: 445 FPENFTERVP 454
FPENFTERVP
Sbjct: 466 FPENFTERVP 475
>gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]
Length = 482
Score = 853 bits (2204), Expect = 0.0
Identities = 439/497 (88%), Positives = 439/497 (88%), Gaps = 58/497 (11%)
Query: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
Query: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
KQHGSNTFTVKAQP SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 285
Query: 301 EPAGGATPGATLPKS-------------------------------------------PS 317
EPAGGATPGATLPKS PS
Sbjct: 286 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 345
Query: 318 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 377
QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD
Sbjct: 346 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 405
Query: 378 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 437
LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE
Sbjct: 406 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 465
Query: 438 LEKCRGVFPENFTERVP 454
LEKCRGVFPENFTERVP
Sbjct: 466 LEKCRGVFPENFTERVP 482
>gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]
Length = 506
Score = 840 bits (2169), Expect = 0.0
Identities = 439/521 (84%), Positives = 439/521 (84%), Gaps = 82/521 (15%)
Query: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
Query: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173
QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
Query: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209
AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
Query: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKN 269
TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP--------------- 285
Query: 270 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPS------------ 317
SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPS
Sbjct: 286 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPS 345
Query: 318 ------------------------QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPA 353
QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPA
Sbjct: 346 GEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPA 405
Query: 354 VVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPF 413
VVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPF
Sbjct: 406 VVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPF 465
Query: 414 QNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 454
QNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 466 QNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 506
>gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]
Length = 409
Score = 802 bits (2071), Expect = 0.0
Identities = 409/454 (90%), Positives = 409/454 (90%), Gaps = 45/454 (9%)
Query: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
Query: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
KQHGSNTFTVKAQP SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 285
Query: 301 EPAGGATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFP 360
EPAGGATPGATLPKSPSQ SSLPAVVVETFP
Sbjct: 286 EPAGGATPGATLPKSPSQ------------------------------SSLPAVVVETFP 315
Query: 361 ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD 420
ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD
Sbjct: 316 ATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQD 375
Query: 421 EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 454
EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 376 EGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 409
>gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]
Length = 518
Score = 796 bits (2056), Expect = 0.0
Identities = 420/533 (78%), Positives = 427/533 (80%), Gaps = 94/533 (17%)
Query: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
Query: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
KQHGSNTFTVKAQP SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 285
Query: 301 EPAGGATPGATLPKSPSQ----------------------------------------PA 320
EPAGGATPGATLPKSPSQ P+
Sbjct: 286 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 345
Query: 321 EASEVAGGTQPA---------------AGAQEPGETAASEA------------------- 346
+ +E G+ P+ + EPG +EA
Sbjct: 346 QPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 405
Query: 347 -----ASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 401
ASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ
Sbjct: 406 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 465
Query: 402 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 454
LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 466 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 518
>gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]
Length = 550
Score = 769 bits (1986), Expect = 0.0
Identities = 419/565 (74%), Positives = 423/565 (74%), Gaps = 126/565 (22%)
Query: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
Query: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173
QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
Query: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209
AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
Query: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKN 269
TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP--------------- 285
Query: 270 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ---PAEASEVA 326
SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ P SE A
Sbjct: 286 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQA 345
Query: 327 G--------------------------------GTQPAAGAQEPGETA------------ 342
T+ AG+ GE +
Sbjct: 346 SLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPS 405
Query: 343 ------------ASEAASSSLPA---------------------VVVETFPATVNGTVEG 369
ASE A + PA VVVETFPATVNGTVEG
Sbjct: 406 QTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEG 465
Query: 370 GSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKE 429
GSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKE
Sbjct: 466 GSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKE 525
Query: 430 SDWNQHKELEKCRGVFPENFTERVP 454
SDWNQHKELEKCRGVFPENFTERVP
Sbjct: 526 SDWNQHKELEKCRGVFPENFTERVP 550
>gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]
Length = 593
Score = 585 bits (1507), Expect = e-167
Identities = 310/397 (78%), Positives = 318/397 (80%), Gaps = 55/397 (13%)
Query: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
Query: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173
QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180
Query: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209
AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240
Query: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKN 269
TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP--------------- 285
Query: 270 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGT 329
SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ + V
Sbjct: 286 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPV---- 341
Query: 330 QPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGT 366
P T + E + ++ +TF ++ T
Sbjct: 342 -----PPPPKHTPSKEVKQEQILSLFEDTFVPEISVT 373
Score = 288 bits (737), Expect = 7e-78
Identities = 148/175 (84%), Positives = 152/175 (86%), Gaps = 7/175 (4%)
Query: 284 PDGSPAATPEIRVNHEPEPAGG----ATPGATLPKSPSQPAEASEVAGGTQPAAGAQEPG 339
P SPA + + EP A G + P T P+QPAEASEVAGGTQPAAGAQEPG
Sbjct: 422 PTESPAGSLP---SGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPG 478
Query: 340 ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDE 399
ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDE
Sbjct: 479 ETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDE 538
Query: 400 LQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 454
LQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 539 LQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 593
>gi|21536423 amphiphysin isoform 2 [Homo sapiens]
Length = 653
Score = 357 bits (917), Expect = 9e-99
Identities = 184/318 (57%), Positives = 226/318 (71%), Gaps = 19/318 (5%)
Query: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
Query: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
Query: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE KAQKVFEE
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
Query: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
NVDLQEELPSLW+ RVGFYVNTF++++ LE FHKE++ L L +V+ L QH F
Sbjct: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243
Query: 249 TVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGAT 307
T++ P SD+ P + K+PSPP + SP +P NH P A+
Sbjct: 244 TIQGAP---------------SDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---AS 285
Query: 308 PGATLPKSPSQPAEASEV 325
P P+SPSQ + V
Sbjct: 286 PAPARPRSPSQTRKGPPV 303
Score = 112 bits (279), Expect = 9e-25
Identities = 64/181 (35%), Positives = 92/181 (50%), Gaps = 16/181 (8%)
Query: 285 DGSPAATPEIRVNHEPEPAGGATPGATL-PKSPSQPAEASEVAGGTQPAAGAQEPGETAA 343
+G+ +A PE P P + P S + +E+ G +P +E E AA
Sbjct: 476 EGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEP----KETTEDAA 531
Query: 344 SEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDY 392
+S P + E P G D LPPGF++KV+ HD+
Sbjct: 532 PPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDF 591
Query: 393 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 452
A ++DEL L+ GDVVLV+P + +QD GWL+GVKESDW Q+++L +G+FPENFT R
Sbjct: 592 EAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRR 651
Query: 453 V 453
+
Sbjct: 652 L 652
>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
Length = 695
Score = 357 bits (917), Expect = 9e-99
Identities = 184/318 (57%), Positives = 226/318 (71%), Gaps = 19/318 (5%)
Query: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
Query: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
Query: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE KAQKVFEE
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
Query: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
NVDLQEELPSLW+ RVGFYVNTF++++ LE FHKE++ L L +V+ L QH F
Sbjct: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243
Query: 249 TVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGAT 307
T++ P SD+ P + K+PSPP + SP +P NH P A+
Sbjct: 244 TIQGAP---------------SDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---AS 285
Query: 308 PGATLPKSPSQPAEASEV 325
P P+SPSQ + V
Sbjct: 286 PAPARPRSPSQTRKGPPV 303
Score = 112 bits (279), Expect = 9e-25
Identities = 64/181 (35%), Positives = 92/181 (50%), Gaps = 16/181 (8%)
Query: 285 DGSPAATPEIRVNHEPEPAGGATPGATL-PKSPSQPAEASEVAGGTQPAAGAQEPGETAA 343
+G+ +A PE P P + P S + +E+ G +P +E E AA
Sbjct: 518 EGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEP----KETTEDAA 573
Query: 344 SEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDY 392
+S P + E P G D LPPGF++KV+ HD+
Sbjct: 574 PPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDF 633
Query: 393 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 452
A ++DEL L+ GDVVLV+P + +QD GWL+GVKESDW Q+++L +G+FPENFT R
Sbjct: 634 EAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRR 693
Query: 453 V 453
+
Sbjct: 694 L 694
>gi|49472835 bridging integrator 2 [Homo sapiens]
Length = 565
Score = 308 bits (788), Expect = 9e-84
Identities = 182/396 (45%), Positives = 235/396 (59%), Gaps = 35/396 (8%)
Query: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
MAE G G AG A VQKK +RAQEKVLQKLGKA ETKDE+FEQ NF +Q EG +
Sbjct: 1 MAE-GKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHK 59
Query: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
L KDL+ +L++VK MHE+SK+++E LQE+Y +W G +E I NNDLLW DY +KL D
Sbjct: 60 LYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLAD 119
Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
QA+ TM+ Y+ QF +IK RIAKRGRKLVDYDSARHH E++Q AKKKDEAK AKAEEE K
Sbjct: 120 QAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNK 179
Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
AQ VFE++N +L EELP L+NSR+G YV FQ+I+ L + F++EMSKLN NL +V+ LE
Sbjct: 180 AQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLE 239
Query: 241 KQHGSNTFTVK---------------------AQPRKKSKLFSRLRRKKNSDNAPAKGNK 279
KQH + F VK + P S L K S++ A +
Sbjct: 240 KQHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDL 299
Query: 280 SPSPPDGSPAA-----TPEIRVNHEPEPAGGATPGATLP----KSPSQPAEASEVAGGTQ 330
+P G + E + E A + LP + +QP+ +E A +
Sbjct: 300 APDAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQE 359
Query: 331 ---PAAGAQEP-GETAASEAASSSLPAVVVETFPAT 362
P++ P G + S SSS VV+ T A+
Sbjct: 360 EVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTAS 395
>gi|8923904 bridging integrator 3 [Homo sapiens]
Length = 253
Score = 57.0 bits (136), Expect = 3e-08
Identities = 55/195 (28%), Positives = 100/195 (51%), Gaps = 14/195 (7%)
Query: 53 KQLTEGTR-LQKDLRTYLASVKAMHEASKKLNECL--QEVYEPDWPGRDEANKI-AENND 108
+QL E TR LQKD++ + AM +++ K++ L + E D +D N + A +
Sbjct: 32 QQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQD---QDLLNMVTALDTA 88
Query: 109 LLWMD-YHQKLVDQALLTMDTYLGQF----PDIKSRIAKRGRKLVDYDSARHHYESLQTA 163
+ MD ++Q+ V+Q T+ L +F P + + +R + L DY + E +
Sbjct: 89 MKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEKYEEK 148
Query: 164 KKKDE--AKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENF 221
+K AK+ +A EEL ++ FE N L EE+P + SR+ ++ +F+S+ + +
Sbjct: 149 EKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRAQVVY 208
Query: 222 HKEMSKLNQNLNDVL 236
+ EM K+ +L+ L
Sbjct: 209 YSEMHKIFGDLSHQL 223
>gi|39930351 dynamin binding protein [Homo sapiens]
Length = 1577
Score = 49.3 bits (116), Expect = 7e-06
Identities = 50/223 (22%), Positives = 90/223 (40%), Gaps = 18/223 (8%)
Query: 17 NVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKA-- 74
++ KK R + G A + KDE FE+ +NF Q +DL YL ++
Sbjct: 996 SIIKKSNRVSSHLKHLTGFAPQIKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIRESA 1055
Query: 75 ---MHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDTYLG 131
+ A + C++ + D + ++ +D L+ ++ ++ + ++ L
Sbjct: 1056 CVKVVAAVSMWDVCMERGHR-DLEQFERVHRYI--SDQLFTNFKERTERLVISPLNQLLS 1112
Query: 132 QFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEMNVD 191
F + KR KL+D+ + E L K K EEL A+ +E +N
Sbjct: 1113 MFTGPHKLVQKRFDKLLDFYNCTERAEKL---------KDKKTLEELQSARNNYEALNAQ 1163
Query: 192 LQEELPSLWNSRVGFYVNTFQSIAGLEENF-HKEMSKLNQNLN 233
L +ELP G + N A +F H+ + +L L+
Sbjct: 1164 LLDELPKFHQYAQGLFTNCVHGYAEAHCDFVHQALEQLKPLLS 1206
Score = 35.8 bits (81), Expect = 0.082
Identities = 25/81 (30%), Positives = 35/81 (43%), Gaps = 15/81 (18%)
Query: 371 SGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKES 430
S + +P M + +A +A +EL + GDV+ +I P GW G
Sbjct: 135 SQSALFQIPEYSMGQARALMGLSAQLDEELDFREGDVITIIGVPEP-----GWFEG---- 185
Query: 431 DWNQHKELEKCRGVFPENFTE 451
ELE RG+FPE F E
Sbjct: 186 ------ELEGRRGIFPEGFVE 200
Score = 31.2 bits (69), Expect = 2.0
Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 15/68 (22%)
Query: 386 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 445
V+A D+ + ++EL L GD++ V+ DE WL+G KE G F
Sbjct: 7 VRAIFDFCPSVSEELPLFVGDIIEVLAV-----VDEFWLLGKKED----------VTGQF 51
Query: 446 PENFTERV 453
P +F E V
Sbjct: 52 PSSFVEIV 59
>gi|49640014 ubiquitin associated and SH3 domain containing, A short
form [Homo sapiens]
Length = 623
Score = 46.2 bits (108), Expect = 6e-05
Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 9/67 (13%)
Query: 386 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 445
++A Y + DEL L GD + V P Q +E EGW++G+ + CRG
Sbjct: 243 LRALFQYKPQNVDELTLSPGDYIFVDPTQQ-DEASEGWVIGISQR--------TGCRGFL 293
Query: 446 PENFTER 452
PEN+T+R
Sbjct: 294 PENYTDR 300
>gi|9507221 ubiquitin associated and SH3 domain containing, A long
form [Homo sapiens]
Length = 661
Score = 46.2 bits (108), Expect = 6e-05
Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 9/67 (13%)
Query: 386 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 445
++A Y + DEL L GD + V P Q +E EGW++G+ + CRG
Sbjct: 281 LRALFQYKPQNVDELTLSPGDYIFVDPTQQ-DEASEGWVIGISQR--------TGCRGFL 331
Query: 446 PENFTER 452
PEN+T+R
Sbjct: 332 PENYTDR 338
>gi|4826964 UV excision repair protein RAD23 homolog A [Homo
sapiens]
Length = 363
Score = 45.4 bits (106), Expect = 1e-04
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 6/80 (7%)
Query: 277 GNKSPSPPDGSPAATPEIRVNHEPEPAGGAT---PGATLPKSPSQ---PAEASEVAGGTQ 330
G + +PP+ SP A PE + P P G + P A KSPS+ P + E G+
Sbjct: 82 GQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAAREDKSPSEESAPTTSPESVSGSV 141
Query: 331 PAAGAQEPGETAASEAASSS 350
P++G+ E AAS + S
Sbjct: 142 PSSGSSGREEDAASTLVTGS 161
>gi|115527120 nebulin [Homo sapiens]
Length = 6669
Score = 44.3 bits (103), Expect = 2e-04
Identities = 38/157 (24%), Positives = 63/157 (40%), Gaps = 39/157 (24%)
Query: 314 KSPSQPAEASEVAGGTQPAAGAQEPGE--------------TAASEAASSSLP---AVVV 356
+ S+ A A ++GG + + ++ P TA A ++ LP + V
Sbjct: 6535 REQSRSASALSISGGEEKSEHSEAPDHHLSTYSDGGVFAVSTAYKHAKTTELPQQRSSSV 6594
Query: 357 ETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNP 416
T TV+ S AG++ +A +DY A D DE+ K GD ++ N
Sbjct: 6595 ATQQTTVSSIPSHPSTAGKI---------FRAMYDYMAADADEVSFKDGDAII-----NV 6640
Query: 417 EEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 453
+ DEGW+ G + G+ P N+ E +
Sbjct: 6641 QAIDEGWMYGTVQRTGR--------TGMLPANYVEAI 6669
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 43.9 bits (102), Expect = 3e-04
Identities = 37/112 (33%), Positives = 46/112 (41%), Gaps = 9/112 (8%)
Query: 273 APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEV--AGGTQ 330
A A G +P +G+P A PE P PAG A PG P+ P P+ + AG
Sbjct: 68 AGAAGAGPAAPAEGAPGAAPE------PPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAP 121
Query: 331 PAAGAQEPGE-TAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPG 381
PAA + P E +A S A + AV PA G A PG
Sbjct: 122 PAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPG 173
Score = 37.4 bits (85), Expect = 0.028
Identities = 34/109 (31%), Positives = 43/109 (39%), Gaps = 18/109 (16%)
Query: 273 APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEASEVAGGTQPA 332
APA + +P +PAA P P PA ATL + P PA A P
Sbjct: 251 APAAPSPPAAPAPAAPAAAPP-----PPPPAP-----ATLARPPGHPAGPPTAAPAVPPP 300
Query: 333 AGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPG 381
A AQ G A+ A + + PA V+G + G GA PG
Sbjct: 301 AAAQNGGSAGAAPAPAPAAGG------PAGVSG--QPGPGAAAAAPAPG 341
Score = 32.7 bits (73), Expect = 0.70
Identities = 36/132 (27%), Positives = 44/132 (33%), Gaps = 31/132 (23%)
Query: 273 APAKGNKSPS----PPDGSPAATPEIRVNH--------EPEPAGGATPGATLPKSPSQPA 320
APA + P PP +PA P + P PA G G + P A
Sbjct: 276 APATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAA 335
Query: 321 EA----------SEVAGGTQPAA---GAQEPGETAASEAASSSL------PAVVVETFPA 361
A V PAA A P TAAS ++ PA V P
Sbjct: 336 AAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPG 395
Query: 362 TVNGTVEGGSGA 373
T G +G +GA
Sbjct: 396 TPTGLPKGAAGA 407
>gi|40807452 peroxisome proliferator-activated receptor gamma,
coactivator-related 1 [Homo sapiens]
Length = 1664
Score = 42.4 bits (98), Expect = 9e-04
Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 9/153 (5%)
Query: 232 LNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAAT 291
+ +V+ L+ + G++ T +A+PR S S RR++ A + +SP PP G +
Sbjct: 726 VKEVVDSLKIESGTSATTHEARPRPLS--LSEYRRRRQQRQAETE-ERSPQPPTGKWPSL 782
Query: 292 PEIRVNHEPEPAGGATPG----ATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAA 347
PE P P L +SP P E V G PA+ + EP + A
Sbjct: 783 PETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEP--PVSKPVA 840
Query: 348 SSSLPAVVVETFPATVNGTVEGGSGAGRLDLPP 380
SS V + P + S + + PP
Sbjct: 841 SSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPP 873
>gi|7662162 ALEX2 protein [Homo sapiens]
Length = 632
Score = 42.4 bits (98), Expect = 9e-04
Identities = 31/113 (27%), Positives = 43/113 (38%), Gaps = 4/113 (3%)
Query: 273 APAKGNKSPSPPDGSPAATPEIRVNHEPEPA----GGATPGATLPKSPSQPAEASEVAGG 328
AP G +PA +V P A PG +P + P E +E G
Sbjct: 140 APPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGPGV 199
Query: 329 TQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPG 381
P A+ PG + +EAA + +PA T G SG+ R + PG
Sbjct: 200 AAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPG 252
>gi|29540562 ALEX2 protein [Homo sapiens]
Length = 632
Score = 42.4 bits (98), Expect = 9e-04
Identities = 31/113 (27%), Positives = 43/113 (38%), Gaps = 4/113 (3%)
Query: 273 APAKGNKSPSPPDGSPAATPEIRVNHEPEPA----GGATPGATLPKSPSQPAEASEVAGG 328
AP G +PA +V P A PG +P + P E +E G
Sbjct: 140 APPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGPGV 199
Query: 329 TQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPG 381
P A+ PG + +EAA + +PA T G SG+ R + PG
Sbjct: 200 AAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPG 252
>gi|219842343 glutamate receptor, metabotropic 5 isoform a precursor
[Homo sapiens]
Length = 1212
Score = 42.0 bits (97), Expect = 0.001
Identities = 35/122 (28%), Positives = 50/122 (40%), Gaps = 14/122 (11%)
Query: 258 SKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPS 317
S + +R + N+ +PSP G+P + + P P +
Sbjct: 1062 SSVVTRFTANISELNSMMLSTAAPSPGVGAPLCSSYLI------PKEIQLPTTMTTFAEI 1115
Query: 318 QPAEASEVAGGTQPAAGAQEPGETA--------ASEAASSSLPAVVVETFPATVNGTVEG 369
QP A EV GG QPAAGAQ G+ A + AA L +V T P+ +V+
Sbjct: 1116 QPLPAIEVTGGAQPAAGAQAAGDAARESPAAGPEAAAAKPDLEELVALTPPSPFRDSVDS 1175
Query: 370 GS 371
GS
Sbjct: 1176 GS 1177
>gi|4504143 glutamate receptor, metabotropic 5 isoform b precursor
[Homo sapiens]
Length = 1180
Score = 42.0 bits (97), Expect = 0.001
Identities = 35/122 (28%), Positives = 50/122 (40%), Gaps = 14/122 (11%)
Query: 258 SKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPS 317
S + +R + N+ +PSP G+P + + P P +
Sbjct: 1030 SSVVTRFTANISELNSMMLSTAAPSPGVGAPLCSSYLI------PKEIQLPTTMTTFAEI 1083
Query: 318 QPAEASEVAGGTQPAAGAQEPGETA--------ASEAASSSLPAVVVETFPATVNGTVEG 369
QP A EV GG QPAAGAQ G+ A + AA L +V T P+ +V+
Sbjct: 1084 QPLPAIEVTGGAQPAAGAQAAGDAARESPAAGPEAAAAKPDLEELVALTPPSPFRDSVDS 1143
Query: 370 GS 371
GS
Sbjct: 1144 GS 1145
>gi|241982780 programmed cell death 6 interacting protein isoform 2
[Homo sapiens]
Length = 873
Score = 42.0 bits (97), Expect = 0.001
Identities = 52/226 (23%), Positives = 88/226 (38%), Gaps = 34/226 (15%)
Query: 173 KAEEELIKAQKVFEEMNVDLQE-ELPSLWNSRVGFYVNTFQSIAGLEENFH------KEM 225
K +E L K + + + + V QE N+ +++A +NF KE
Sbjct: 619 KVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVELVANLKEG 678
Query: 226 SKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSK-LFSRLRRKKNSDNAPAK-------G 277
+K L ++LV + + F K + + K L + R+ ++ + P G
Sbjct: 679 TKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPTPAYQSSPAG 738
Query: 278 NKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEA-SEVAGGTQPAAGAQ 336
+P+PP +P P + P+P P LP + + A A S V GT A +Q
Sbjct: 739 GHAPTPPTPAPRTMPPTK----PQPPARPPP-PVLPANRAPSATAPSPVGAGTAAPAPSQ 793
Query: 337 EPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGF 382
PG +A P T+P G G ++ +P G+
Sbjct: 794 TPGSAPPPQAQGPPYP-----TYP--------GYPGYCQMPMPMGY 826
>gi|22027538 programmed cell death 6 interacting protein isoform 1
[Homo sapiens]
Length = 868
Score = 42.0 bits (97), Expect = 0.001
Identities = 52/226 (23%), Positives = 88/226 (38%), Gaps = 34/226 (15%)
Query: 173 KAEEELIKAQKVFEEMNVDLQE-ELPSLWNSRVGFYVNTFQSIAGLEENFH------KEM 225
K +E L K + + + + V QE N+ +++A +NF KE
Sbjct: 614 KVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVELVANLKEG 673
Query: 226 SKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSK-LFSRLRRKKNSDNAPAK-------G 277
+K L ++LV + + F K + + K L + R+ ++ + P G
Sbjct: 674 TKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPTPAYQSSPAG 733
Query: 278 NKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEA-SEVAGGTQPAAGAQ 336
+P+PP +P P + P+P P LP + + A A S V GT A +Q
Sbjct: 734 GHAPTPPTPAPRTMPPTK----PQPPARPPP-PVLPANRAPSATAPSPVGAGTAAPAPSQ 788
Query: 337 EPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGF 382
PG +A P T+P G G ++ +P G+
Sbjct: 789 TPGSAPPPQAQGPPYP-----TYP--------GYPGYCQMPMPMGY 821
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 41.6 bits (96), Expect = 0.001
Identities = 57/267 (21%), Positives = 111/267 (41%), Gaps = 30/267 (11%)
Query: 11 AGKIASNVQKKLTRAQEKVLQKLGKAD-ETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYL 69
A + N + +L + +LQ GK D E K ++ E +Q + EG R++ +L +
Sbjct: 1218 AKQTLENERGELANEVKVLLQ--GKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKV 1275
Query: 70 ASVKAMHEASKKL---NECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTM 126
++ + L ++ D+ + +++ + +LL + QKL ++
Sbjct: 1276 TKLQVELDNVTGLLSQSDSKSSKLTKDFSALE--SQLQDTQELLQEENRQKL------SL 1327
Query: 127 DTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFE 186
T L Q D K+ ++ L + + A+H+ E A + K E+ + + E
Sbjct: 1328 STKLKQVEDEKNSFREQ---LEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAE 1384
Query: 187 EMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSN 246
E+ LQ++L L + + K ++L Q L+D+LV L+ Q S
Sbjct: 1385 EVKRKLQKDLEGL--------SQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQS- 1435
Query: 247 TFTVKAQPRKKSKLFSRLRRKKNSDNA 273
KK K F +L ++ + +A
Sbjct: 1436 ----ACNLEKKQKKFDQLLAEEKTISA 1458
Score = 35.0 bits (79), Expect = 0.14
Identities = 35/137 (25%), Positives = 63/137 (45%), Gaps = 20/137 (14%)
Query: 136 IKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEMNVDLQEE 195
++ I + +L + +SAR + LQ K EAK+ K EEE Q + E+ N L +E
Sbjct: 941 MQQNIQELEEQLEEEESAR---QKLQLEKVTTEAKLKKLEEE----QIILEDQNCKLAKE 993
Query: 196 LPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPR 255
L + F N + EE K ++KL ++ LE++ ++ + +
Sbjct: 994 KKLLEDRIAEFTTNLTE-----EEEKSKSLAKLKNKHEAMITDLEER-------LRREEK 1041
Query: 256 KKSKLFSRLRRKKNSDN 272
++ +L + RRK D+
Sbjct: 1042 QRQEL-EKTRRKLEGDS 1057
Score = 33.9 bits (76), Expect = 0.31
Identities = 54/264 (20%), Positives = 111/264 (42%), Gaps = 35/264 (13%)
Query: 13 KIASNVQKKLTRAQ-EKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQ--------- 62
K+ V + +AQ E+ LQ + E K +Q + V+ +L + + +
Sbjct: 1555 KLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKK 1614
Query: 63 -----KDLRTYLAS--------VKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDL 109
KDL ++ S +K + + ++ +C++E+ + + + EN
Sbjct: 1615 LEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKK 1674
Query: 110 LWMDYHQKLVDQALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKD-E 168
L K ++ ++ + L K + + +L D + +L +K+ E
Sbjct: 1675 L------KSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLE 1728
Query: 169 AKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKL 228
A+IA+ EEEL + Q E +N L++ +L ++ +N +S A EN +++ +
Sbjct: 1729 ARIAQLEEELEEEQGNTELINDRLKK--ANLQIDQINTDLNLERSHAQKNENARQQLERQ 1786
Query: 229 NQNLNDVLVGLEKQHGSNTFTVKA 252
N+ L V L++ G+ KA
Sbjct: 1787 NKELK---VKLQEMEGTVKSKYKA 1807
>gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo
sapiens]
Length = 384
Score = 40.8 bits (94), Expect = 0.003
Identities = 37/117 (31%), Positives = 49/117 (41%), Gaps = 11/117 (9%)
Query: 262 SRLRRKKNSDNAPAKGNKSPSP-PDGS--PAATP-EIRVNHEPEPAGGATPGATLPKSPS 317
SRL R S + A S +P PD PAA P R P +G T + +P PS
Sbjct: 52 SRLERGTFSPESAAGTEVSGAPHPDSRTRPAARPPHPRTRSPPGRSGSGTTFSAVPPRPS 111
Query: 318 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAG 374
Q S + +PAA PG ++A + + + P T P GGSG G
Sbjct: 112 QHQSGSRL----RPAAPGPRPGCSSARASPAPAAPQAAARTAPGR---AASGGSGPG 161
>gi|239749199 PREDICTED: hypothetical protein XP_002346952 [Homo
sapiens]
Length = 209
Score = 40.8 bits (94), Expect = 0.003
Identities = 37/117 (31%), Positives = 49/117 (41%), Gaps = 11/117 (9%)
Query: 262 SRLRRKKNSDNAPAKGNKSPSP-PDGS--PAATP-EIRVNHEPEPAGGATPGATLPKSPS 317
SRL R S + A S +P PD PAA P R P +G T + +P PS
Sbjct: 52 SRLERGTFSPESAAGTEVSGAPHPDSRTRPAARPPHPRTRSPPGRSGSGTTFSAVPPRPS 111
Query: 318 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAG 374
Q S + +PAA PG ++A + + + P T P GGSG G
Sbjct: 112 QHQSGSRL----RPAAPGPRPGCSSARASPAPAAPQAAARTAPGR---AASGGSGPG 161
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,753,756
Number of Sequences: 37866
Number of extensions: 997143
Number of successful extensions: 8217
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 115
Number of HSP's successfully gapped in prelim test: 712
Number of HSP's that attempted gapping in prelim test: 6576
Number of HSP's gapped (non-prelim): 2074
length of query: 454
length of database: 18,247,518
effective HSP length: 106
effective length of query: 348
effective length of database: 14,233,722
effective search space: 4953335256
effective search space used: 4953335256
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.