Search of human proteins with 46485465

Search of human proteins with 46485465

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46485465 Numb-interacting protein [Homo sapiens]
         (483 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46485465 Numb-interacting protein [Homo sapiens]                   995   0.0  
gi|98986325 dual oxidase activator 2 [Homo sapiens]                   338   5e-93
gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapi...    42   0.001
gi|239757609 PREDICTED: hypothetical protein [Homo sapiens]            33   0.75 
gi|239757081 PREDICTED: hypothetical protein LOC100127987 [Homo ...    33   0.75 
gi|239752116 PREDICTED: hypothetical protein XP_002348117 [Homo ...    33   0.75 
gi|169213239 PREDICTED: hypothetical protein LOC100127987 [Homo ...    33   0.75 
gi|239746618 PREDICTED: hypothetical protein XP_002344233 [Homo ...    33   0.75 
gi|169212748 PREDICTED: hypothetical protein LOC100127987 [Homo ...    33   0.75 
gi|40254921 transmembrane protein 144 [Homo sapiens]                   33   0.75 
gi|9506615 protein arginine methyltransferase 7 [Homo sapiens]         32   0.99 
gi|188536004 zinc finger protein 469 [Homo sapiens]                    32   0.99 
gi|122937249 glutamate receptor interacting protein 2 [Homo sapi...    32   0.99 
gi|5901884 cytochrome b-561 domain containing 2 [Homo sapiens]         32   0.99 
gi|4503509 eukaryotic translation initiation factor 3, subunit 1...    32   1.7  
gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa...    31   2.9  
gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa...    31   2.9  
gi|216547801 SH2 domain containing 3C isoform e [Homo sapiens]         31   2.9  
gi|216547790 SH2 domain containing 3C isoform d [Homo sapiens]         31   2.9  
gi|216547779 SH2 domain containing 3C isoform c [Homo sapiens]         31   2.9  
gi|216547769 SH2 domain containing 3C isoform c [Homo sapiens]         31   2.9  
gi|216547763 SH2 domain containing 3C isoform b [Homo sapiens]         31   2.9  
gi|41281821 SH2 domain containing 3C isoform a [Homo sapiens]          31   2.9  
gi|253970412 G-2 and S-phase expressed 1 [Homo sapiens]                30   4.9  
gi|239754514 PREDICTED: hypothetical protein [Homo sapiens]            30   6.4  
gi|169214254 PREDICTED: transmembrane protein 221 [Homo sapiens]       30   6.4  
gi|169213600 PREDICTED: transmembrane protein 221 [Homo sapiens]       30   6.4  
gi|11415040 matriptase [Homo sapiens]                                  30   6.4  
gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein ...    30   6.4  
gi|22547201 zinc finger protein of the cerebellum 4 [Homo sapiens]     30   6.4  

>gi|46485465 Numb-interacting protein [Homo sapiens]
          Length = 483

 Score =  995 bits (2573), Expect = 0.0
 Identities = 483/483 (100%), Positives = 483/483 (100%)

Query: 1   MATLGHTFPFYAGPKPTFPMDTTLASIIMIFLTALATFIVILPGIRGKTRLFWLLRVVTS 60
           MATLGHTFPFYAGPKPTFPMDTTLASIIMIFLTALATFIVILPGIRGKTRLFWLLRVVTS
Sbjct: 1   MATLGHTFPFYAGPKPTFPMDTTLASIIMIFLTALATFIVILPGIRGKTRLFWLLRVVTS 60

Query: 61  LFIGAAILAVNFSSEWSVGQVSTNTSYKAFSSEWISADIGLQVGLGGVNITLTGTPVQQL 120
           LFIGAAILAVNFSSEWSVGQVSTNTSYKAFSSEWISADIGLQVGLGGVNITLTGTPVQQL
Sbjct: 61  LFIGAAILAVNFSSEWSVGQVSTNTSYKAFSSEWISADIGLQVGLGGVNITLTGTPVQQL 120

Query: 121 NETINYNEEFTWRLGENYAEEYAKALEKGLPDPVLYLAEKFTPRSPCGLYRQYRLAGHYT 180
           NETINYNEEFTWRLGENYAEEYAKALEKGLPDPVLYLAEKFTPRSPCGLYRQYRLAGHYT
Sbjct: 121 NETINYNEEFTWRLGENYAEEYAKALEKGLPDPVLYLAEKFTPRSPCGLYRQYRLAGHYT 180

Query: 181 SAMLWVAFLCWLLANVMLSMPVLVYGGYMLLATGIFQLLALLFFSMATSLTSPCPLHLGA 240
           SAMLWVAFLCWLLANVMLSMPVLVYGGYMLLATGIFQLLALLFFSMATSLTSPCPLHLGA
Sbjct: 181 SAMLWVAFLCWLLANVMLSMPVLVYGGYMLLATGIFQLLALLFFSMATSLTSPCPLHLGA 240

Query: 241 SVLHTHHGPAFWITLTTGLLCVLLGLAMAVAHRMQPHRLKAFFNQSVDEDPMLEWSPEEG 300
           SVLHTHHGPAFWITLTTGLLCVLLGLAMAVAHRMQPHRLKAFFNQSVDEDPMLEWSPEEG
Sbjct: 241 SVLHTHHGPAFWITLTTGLLCVLLGLAMAVAHRMQPHRLKAFFNQSVDEDPMLEWSPEEG 300

Query: 301 GLLSPRYRSMADSPKSQDIPLSEASSTKAYYRPRRLSLVPADVRGLAPAALSALPGALLA 360
           GLLSPRYRSMADSPKSQDIPLSEASSTKAYYRPRRLSLVPADVRGLAPAALSALPGALLA
Sbjct: 301 GLLSPRYRSMADSPKSQDIPLSEASSTKAYYRPRRLSLVPADVRGLAPAALSALPGALLA 360

Query: 361 QAWRALLPGLRCPKAGKESRLGPPHSPWRFGPEGCEERWAEHTGDSPRPLRGRGTGRLWR 420
           QAWRALLPGLRCPKAGKESRLGPPHSPWRFGPEGCEERWAEHTGDSPRPLRGRGTGRLWR
Sbjct: 361 QAWRALLPGLRCPKAGKESRLGPPHSPWRFGPEGCEERWAEHTGDSPRPLRGRGTGRLWR 420

Query: 421 WGSKERRACGVRAMLPRLVSNSGLKRPSCLDLPKCWDYRRDARAFFHLLEPTPCVTSRHT 480
           WGSKERRACGVRAMLPRLVSNSGLKRPSCLDLPKCWDYRRDARAFFHLLEPTPCVTSRHT
Sbjct: 421 WGSKERRACGVRAMLPRLVSNSGLKRPSCLDLPKCWDYRRDARAFFHLLEPTPCVTSRHT 480

Query: 481 PLI 483
           PLI
Sbjct: 481 PLI 483


>gi|98986325 dual oxidase activator 2 [Homo sapiens]
          Length = 320

 Score =  338 bits (868), Expect = 5e-93
 Identities = 172/294 (58%), Positives = 212/294 (72%), Gaps = 8/294 (2%)

Query: 9   PFYAGPKPTFPMDTTLASIIMIFLTALATFIVILPGIRGKTRLFWLLRVVTSLFIGAAIL 68
           PFY  P+        L  +I++FL   A+F++ILPGIRG +R FWL+RV+ SLFIGA I+
Sbjct: 9   PFYPQPRHAAGFSVPLLIVILVFLALAASFLLILPGIRGHSRWFWLVRVLLSLFIGAEIV 68

Query: 69  AVNFSSEWSVGQVSTNTSYKAFSSEWISADIGLQVGLGGVNITLTGTPVQQLNETINYNE 128
           AV+FS+EW VG V+TNTSYKAFS+  ++A + L VGL G+NITLTGTPV QLNETI+YNE
Sbjct: 69  AVHFSAEWFVGTVNTNTSYKAFSAARVTARVRLLVGLEGINITLTGTPVHQLNETIDYNE 128

Query: 129 EFTWRLGENYAEEYAKALEKGLPDPVLYLAEKFTPRSPCGLYRQYRLAGHYTSAMLWVAF 188
           +FTWRL ENYA EYA ALEKGLPDPVLYLAEKFTP SPCGLY QY LAGHY SA LWVAF
Sbjct: 129 QFTWRLKENYAAEYANALEKGLPDPVLYLAEKFTPSSPCGLYHQYHLAGHYASATLWVAF 188

Query: 189 LCWLLANVMLSMPVLVYGGYMLLATGIFQLLALLFFSMATSLTSP-CPLHLGASVLHTHH 247
             WLL+NV+LS P  +YGG  LL TG F L  +  F++A+  + P CPL LG+S L T +
Sbjct: 189 CFWLLSNVLLSTPAPLYGGLALLTTGAFALFGV--FALASISSVPLCPLRLGSSALTTQY 246

Query: 248 GPAFWITLTTGLLCVLLGLAMAVAHRMQPHRLKAFFNQSVDEDPMLEWSPEEGG 301
           G AFW+TL TG+LC+ LG A+     ++P  L+   +QS       + S E GG
Sbjct: 247 GAAFWVTLATGVLCLFLGGAVVSLQYVRPSALRTLLDQSAK-----DCSQERGG 295


>gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo
           sapiens]
          Length = 464

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/33 (66%), Positives = 22/33 (66%)

Query: 427 RACGVRAMLPRLVSNSGLKRPSCLDLPKCWDYR 459
           R  G   M PRLVSNS LKR S L LPK WDYR
Sbjct: 99  RKDGDLTMWPRLVSNSKLKRSSHLSLPKYWDYR 131


>gi|239757609 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 571

 Score = 32.7 bits (73), Expect = 0.75
 Identities = 29/84 (34%), Positives = 38/84 (45%), Gaps = 11/84 (13%)

Query: 382 GPPHSPWRFGPE--GCEERWAEHTGDSPRPLRGRGTGRLWRWGSKERRACGVRAMLPRLV 439
           G PH P     +  GC+ R    TG      RGRG GRL    S+E       A      
Sbjct: 314 GHPHEPCYTSIDEFGCDAR----TGGGQGEERGRGRGRLGSGCSQE----WAGAQTVGNP 365

Query: 440 SNSGLKRPSCLDLPKCWDYRRDAR 463
           S +G++RPS   L + W  R+D+R
Sbjct: 366 SPTGVQRPSSASLAQVWS-RQDSR 388


>gi|239757081 PREDICTED: hypothetical protein LOC100127987 [Homo
           sapiens]
          Length = 755

 Score = 32.7 bits (73), Expect = 0.75
 Identities = 25/72 (34%), Positives = 29/72 (40%), Gaps = 7/72 (9%)

Query: 384 PHSPWRFGPEGCEERWAEHTGDSPRPLRGRGTGRLWRWGSKERRACGVRAMLPRLVSNSG 443
           P S    GPE      A  T  SPRP  G G  + WR G+ E  A G R       S  G
Sbjct: 231 PLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQTWRQGAGE--AQGTRG-----GSADG 283

Query: 444 LKRPSCLDLPKC 455
           +   +C    KC
Sbjct: 284 IPELTCYQRSKC 295


>gi|239752116 PREDICTED: hypothetical protein XP_002348117 [Homo
           sapiens]
          Length = 571

 Score = 32.7 bits (73), Expect = 0.75
 Identities = 29/84 (34%), Positives = 38/84 (45%), Gaps = 11/84 (13%)

Query: 382 GPPHSPWRFGPE--GCEERWAEHTGDSPRPLRGRGTGRLWRWGSKERRACGVRAMLPRLV 439
           G PH P     +  GC+ R    TG      RGRG GRL    S+E       A      
Sbjct: 314 GHPHEPCYTSIDEFGCDAR----TGGGQGEERGRGRGRLGSGCSQE----WAGAQTVGNP 365

Query: 440 SNSGLKRPSCLDLPKCWDYRRDAR 463
           S +G++RPS   L + W  R+D+R
Sbjct: 366 SPTGVQRPSSASLAQVWS-RQDSR 388


>gi|169213239 PREDICTED: hypothetical protein LOC100127987 [Homo
           sapiens]
          Length = 755

 Score = 32.7 bits (73), Expect = 0.75
 Identities = 25/72 (34%), Positives = 29/72 (40%), Gaps = 7/72 (9%)

Query: 384 PHSPWRFGPEGCEERWAEHTGDSPRPLRGRGTGRLWRWGSKERRACGVRAMLPRLVSNSG 443
           P S    GPE      A  T  SPRP  G G  + WR G+ E  A G R       S  G
Sbjct: 231 PLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQTWRQGAGE--AQGTRG-----GSADG 283

Query: 444 LKRPSCLDLPKC 455
           +   +C    KC
Sbjct: 284 IPELTCYQRSKC 295


>gi|239746618 PREDICTED: hypothetical protein XP_002344233 [Homo
           sapiens]
          Length = 571

 Score = 32.7 bits (73), Expect = 0.75
 Identities = 29/84 (34%), Positives = 38/84 (45%), Gaps = 11/84 (13%)

Query: 382 GPPHSPWRFGPE--GCEERWAEHTGDSPRPLRGRGTGRLWRWGSKERRACGVRAMLPRLV 439
           G PH P     +  GC+ R    TG      RGRG GRL    S+E       A      
Sbjct: 314 GHPHEPCYTSIDEFGCDAR----TGGGQGEERGRGRGRLGSGCSQE----WAGAQTVGNP 365

Query: 440 SNSGLKRPSCLDLPKCWDYRRDAR 463
           S +G++RPS   L + W  R+D+R
Sbjct: 366 SPTGVQRPSSASLAQVWS-RQDSR 388


>gi|169212748 PREDICTED: hypothetical protein LOC100127987 [Homo
           sapiens]
          Length = 755

 Score = 32.7 bits (73), Expect = 0.75
 Identities = 25/72 (34%), Positives = 29/72 (40%), Gaps = 7/72 (9%)

Query: 384 PHSPWRFGPEGCEERWAEHTGDSPRPLRGRGTGRLWRWGSKERRACGVRAMLPRLVSNSG 443
           P S    GPE      A  T  SPRP  G G  + WR G+ E  A G R       S  G
Sbjct: 231 PLSQHPTGPEPSSRPHALSTAASPRPCWGAGHSQTWRQGAGE--AQGTRG-----GSADG 283

Query: 444 LKRPSCLDLPKC 455
           +   +C    KC
Sbjct: 284 IPELTCYQRSKC 295


>gi|40254921 transmembrane protein 144 [Homo sapiens]
          Length = 345

 Score = 32.7 bits (73), Expect = 0.75
 Identities = 32/120 (26%), Positives = 53/120 (44%), Gaps = 10/120 (8%)

Query: 105 LGGVNITLTGTPVQQLNETINYNEEFTWRLGENYAEEYAKALEKG--LPDPVLYLAEKFT 162
           + GV    T  P+  + +    N+   +     Y  +Y  A   G  L   V +LA    
Sbjct: 195 ISGVLYGSTFVPIIYIKDHSKRNDSI-YAGASQYDLDYVFAHFSGIFLTSTVYFLAYCIA 253

Query: 163 PRSPCGLYRQYRLAGHYTSAMLW-VAFLCWLLAN----VMLSMPVLVYG-GYMLLATGIF 216
            ++   LY +  L G + S +LW +A  CW +AN     ++S P++  G G++    GIF
Sbjct: 254 MKNSPKLYPEAVLPG-FLSGVLWAIATCCWFIANHSLSAVVSFPIITAGPGFIAAMWGIF 312


>gi|9506615 protein arginine methyltransferase 7 [Homo sapiens]
          Length = 692

 Score = 32.3 bits (72), Expect = 0.99
 Identities = 27/103 (26%), Positives = 37/103 (35%), Gaps = 6/103 (5%)

Query: 377 KESRLGPPHSPWRFGPEGCEERWAEHTGDSP-----RPLRGRGTGRLWRWGSKERRACGV 431
           +ESR   PH  W +      E W   T D       +PL   GT  L R G        +
Sbjct: 556 RESREAEPHPLWEYPCRSLSEPWQILTFDFQQPVPLQPLCAEGTVELRRPGQSHAAVLWM 615

Query: 432 RAML-PRLVSNSGLKRPSCLDLPKCWDYRRDARAFFHLLEPTP 473
              L P    ++GL  P+  +   CW+       +F    P P
Sbjct: 616 EYHLTPECTLSTGLLEPADPEGGCCWNPHCKQAVYFFSPAPDP 658


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 32.3 bits (72), Expect = 0.99
 Identities = 43/169 (25%), Positives = 64/169 (37%), Gaps = 30/169 (17%)

Query: 289  EDPMLEWSPEEGGLLSPRYRSMADSPKSQDIPLSEASSTKAYYRPRRLSLVPADVRGLAP 348
            EDP   W P  G + +       D+PK   + + E S  +  +     +  P     ++P
Sbjct: 2195 EDPS-SWPP--GSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSP 2251

Query: 349  AA------LSALPGALLAQAWRALLPGLRCPKAGKESRLGPPHSPWRFGPEGCEERWAEH 402
            +       LS+ P    AQA R L      P    +SR  PPH+     P G       H
Sbjct: 2252 SVAVRATGLSSTPTGDEAQAGRGL------PGPDPQSRGAPPHTNPDRMPRG-------H 2298

Query: 403  TGDSPRPLRGRGTGRLWRWGSKERRACGVRAMLPRLVSNSGLKRPSCLD 451
            +  SP       T RL   G +E +A       P  +  +G   P+CL+
Sbjct: 2299 SSYSP-----SNTARL---GHREGQAVTAVPTEPPTLQGAGPDSPACLE 2339


>gi|122937249 glutamate receptor interacting protein 2 [Homo sapiens]
          Length = 1141

 Score = 32.3 bits (72), Expect = 0.99
 Identities = 48/195 (24%), Positives = 74/195 (37%), Gaps = 24/195 (12%)

Query: 288  DEDPMLEWSPEEGGLLSPRYRSMADSPKSQDIPLSEASSTKAYYRPRRLSLVPADVRGLA 347
            DEDP       +GGL + R+     S  S  +   ++S+T+  +         A  RG  
Sbjct: 855  DEDPA---DALKGGLPAARFSPAVPSVDSA-VESWDSSATEGGFGGPGSYTPQAAARGTT 910

Query: 348  PAALSALPGALLAQAWRALLPGLRCPKAGKESRLGPPHSPWRFGPEGCEERWAEHTGDSP 407
            P      PG      W   L G   P   + +   P  +   F  E  E+ W   T  +P
Sbjct: 911  PQ--ERRPG------W---LRGSPPPTEPRRTSYTPTPADESFPEEEEEDDWEPPTSPAP 959

Query: 408  RPLRGRGTGRLWRWGSKERRACGVRAMLPRL---VSNSGLKRPSCLDLP--KCWDYRRDA 462
             P R  G  R++    ++  +CG   +L  L   +    ++R +    P  + W   R+ 
Sbjct: 960  GPAREEGFWRMFGEALEDLESCGQSELLRELEASIMTGTVQRVALEGRPGHRPWQRGREV 1019

Query: 463  RA----FFHLLEPTP 473
            RA       LL PTP
Sbjct: 1020 RASPAEMEELLLPTP 1034


>gi|5901884 cytochrome b-561 domain containing 2 [Homo sapiens]
          Length = 222

 Score = 32.3 bits (72), Expect = 0.99
 Identities = 23/67 (34%), Positives = 29/67 (43%), Gaps = 8/67 (11%)

Query: 209 MLLATGIFQLLALLFFSMATSLTSPCPLHLGASVLHTHHGPAFWITLTTGLLCVLLGLAM 268
           M LA       ALL FS  +SL     LH   S+         W+     LLC LLGL +
Sbjct: 52  MSLAFSFLMTEALLVFSPESSL-----LH---SLSRKGRARCHWVLQLLALLCALLGLGL 103

Query: 269 AVAHRMQ 275
            + H+ Q
Sbjct: 104 VILHKEQ 110


>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
           theta, 150/170kDa [Homo sapiens]
          Length = 1382

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 17/39 (43%), Positives = 19/39 (48%), Gaps = 2/39 (5%)

Query: 373 PKAGKESRLGPPHSPWRFGPEGCEERWAEHTGDSPRPLR 411
           P+A  E R GPP   WR G    E+R   H  D  RP R
Sbjct: 903 PEADSEWRRGPPEKEWRRGEGRDEDR--SHRRDEERPRR 939


>gi|90669191 solute carrier family 22 member 7 isoform b [Homo
           sapiens]
          Length = 548

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 18/34 (52%), Positives = 20/34 (58%)

Query: 186 VAFLCWLLANVMLSMPVLVYGGYMLLATGIFQLL 219
           +A L  LL  V LS+P L YGG  LLA G   LL
Sbjct: 479 LAPLAALLDGVWLSLPKLTYGGIALLAAGTALLL 512


>gi|24497497 solute carrier family 22 member 7 isoform a [Homo
           sapiens]
          Length = 546

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 18/34 (52%), Positives = 20/34 (58%)

Query: 186 VAFLCWLLANVMLSMPVLVYGGYMLLATGIFQLL 219
           +A L  LL  V LS+P L YGG  LLA G   LL
Sbjct: 477 LAPLAALLDGVWLSLPKLTYGGIALLAAGTALLL 510


>gi|216547801 SH2 domain containing 3C isoform e [Homo sapiens]
          Length = 700

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 9/70 (12%)

Query: 320 PLSEASSTKAYYRPRRLSLVPADVRGLAPAALSALPGALLAQ--AWRALLPGLRCPKAGK 377
           P+SE+ S+ AY    R+   PA     AP+A +ALP + +A+  +   L PG   PK   
Sbjct: 249 PISESPSSPAYSTVTRVHAAPA-----APSA-TALPASPVARRSSEPQLCPG-SAPKTHG 301

Query: 378 ESRLGPPHSP 387
           ES  GP  SP
Sbjct: 302 ESDKGPHTSP 311


>gi|216547790 SH2 domain containing 3C isoform d [Homo sapiens]
          Length = 702

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 9/70 (12%)

Query: 320 PLSEASSTKAYYRPRRLSLVPADVRGLAPAALSALPGALLAQ--AWRALLPGLRCPKAGK 377
           P+SE+ S+ AY    R+   PA     AP+A +ALP + +A+  +   L PG   PK   
Sbjct: 251 PISESPSSPAYSTVTRVHAAPA-----APSA-TALPASPVARRSSEPQLCPG-SAPKTHG 303

Query: 378 ESRLGPPHSP 387
           ES  GP  SP
Sbjct: 304 ESDKGPHTSP 313


>gi|216547779 SH2 domain containing 3C isoform c [Homo sapiens]
          Length = 506

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 9/70 (12%)

Query: 320 PLSEASSTKAYYRPRRLSLVPADVRGLAPAALSALPGALLAQ--AWRALLPGLRCPKAGK 377
           P+SE+ S+ AY    R+   PA     AP+A +ALP + +A+  +   L PG   PK   
Sbjct: 55  PISESPSSPAYSTVTRVHAAPA-----APSA-TALPASPVARRSSEPQLCPG-SAPKTHG 107

Query: 378 ESRLGPPHSP 387
           ES  GP  SP
Sbjct: 108 ESDKGPHTSP 117


>gi|216547769 SH2 domain containing 3C isoform c [Homo sapiens]
          Length = 506

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 9/70 (12%)

Query: 320 PLSEASSTKAYYRPRRLSLVPADVRGLAPAALSALPGALLAQ--AWRALLPGLRCPKAGK 377
           P+SE+ S+ AY    R+   PA     AP+A +ALP + +A+  +   L PG   PK   
Sbjct: 55  PISESPSSPAYSTVTRVHAAPA-----APSA-TALPASPVARRSSEPQLCPG-SAPKTHG 107

Query: 378 ESRLGPPHSP 387
           ES  GP  SP
Sbjct: 108 ESDKGPHTSP 117


>gi|216547763 SH2 domain containing 3C isoform b [Homo sapiens]
          Length = 703

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 9/70 (12%)

Query: 320 PLSEASSTKAYYRPRRLSLVPADVRGLAPAALSALPGALLAQ--AWRALLPGLRCPKAGK 377
           P+SE+ S+ AY    R+   PA     AP+A +ALP + +A+  +   L PG   PK   
Sbjct: 252 PISESPSSPAYSTVTRVHAAPA-----APSA-TALPASPVARRSSEPQLCPG-SAPKTHG 304

Query: 378 ESRLGPPHSP 387
           ES  GP  SP
Sbjct: 305 ESDKGPHTSP 314


>gi|41281821 SH2 domain containing 3C isoform a [Homo sapiens]
          Length = 860

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 9/70 (12%)

Query: 320 PLSEASSTKAYYRPRRLSLVPADVRGLAPAALSALPGALLAQ--AWRALLPGLRCPKAGK 377
           P+SE+ S+ AY    R+   PA     AP+A +ALP + +A+  +   L PG   PK   
Sbjct: 409 PISESPSSPAYSTVTRVHAAPA-----APSA-TALPASPVARRSSEPQLCPG-SAPKTHG 461

Query: 378 ESRLGPPHSP 387
           ES  GP  SP
Sbjct: 462 ESDKGPHTSP 471


>gi|253970412 G-2 and S-phase expressed 1 [Homo sapiens]
          Length = 739

 Score = 30.0 bits (66), Expect = 4.9
 Identities = 24/95 (25%), Positives = 31/95 (32%), Gaps = 24/95 (25%)

Query: 364 RALLPGLRCPKAGKESRL----GPPHSPWRFGPEGCEERWAEHTGDSPRPLRGRGTGRLW 419
           R L      P +G ++RL    GPPHS      E C    A       +P          
Sbjct: 182 RLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKP---------- 231

Query: 420 RWGSKERRACGVRAMLPRLVSNSGLKRPSCLDLPK 454
                     G + +LPR  S  G   P   + PK
Sbjct: 232 ----------GTKLLLPRAASVRGRSIPGAAEKPK 256


>gi|239754514 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 260

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 34/109 (31%), Positives = 41/109 (37%), Gaps = 27/109 (24%)

Query: 362 AWRALLPGLRCPKAGKESRLGPPHSPWRFGPEGCEERWAEHTGDSPRPLRGR-------- 413
           A R   P  RCP+     RLG    P   GP   E   A H    PRP  G         
Sbjct: 33  ARRRAAPAPRCPQ-----RLGLLRPP---GPTNSEFPRAWH----PRPPPGHLPMWLSSM 80

Query: 414 ---GTGRLWRWGSKE-RRACGVRAMLPRLVSNSGLKRPSCLDLPKCWDY 458
               + R+ +W  +   R     A+ P    + GL     L LPKCWDY
Sbjct: 81  CSMRSARVGKWSPQPPNRQRWSFAICPGWTRSPGLNH---LGLPKCWDY 126


>gi|169214254 PREDICTED: transmembrane protein 221 [Homo sapiens]
          Length = 291

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 20/41 (48%), Positives = 23/41 (56%), Gaps = 2/41 (4%)

Query: 345 GLAPAALSALPGALL--AQAWRALLPGLRCPKAGKESRLGP 383
           G+A A L+AL   LL   QA RA L GLR    G+E   GP
Sbjct: 17  GIAAAVLAALGAQLLFQLQAGRAELRGLRAEGLGQELGAGP 57


>gi|169213600 PREDICTED: transmembrane protein 221 [Homo sapiens]
          Length = 291

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 20/41 (48%), Positives = 23/41 (56%), Gaps = 2/41 (4%)

Query: 345 GLAPAALSALPGALL--AQAWRALLPGLRCPKAGKESRLGP 383
           G+A A L+AL   LL   QA RA L GLR    G+E   GP
Sbjct: 17  GIAAAVLAALGAQLLFQLQAGRAELRGLRAEGLGQELGAGP 57


>gi|11415040 matriptase [Homo sapiens]
          Length = 855

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 4/42 (9%)

Query: 247 HGPAFWITLTT---GLLCVLLGLAMAVAH-RMQPHRLKAFFN 284
           HGP  W+ L     GLL VLLG+   V H + +  R++  FN
Sbjct: 50  HGPGRWVVLAAVLIGLLLVLLGIGFLVWHLQYRDVRVQKVFN 91


>gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein
           [Homo sapiens]
          Length = 593

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 28/84 (33%), Positives = 32/84 (38%), Gaps = 13/84 (15%)

Query: 339 VPADVRGLAPAALSALP-------GALLAQAWRALLPGLRCPKAGKESRLGPPHSPW--R 389
           +P D     P    A P        A + +A  A L  +R   AG    LG P SP    
Sbjct: 27  LPPDPPAAPPGRARAAPDEDREPESARMQRAQMAALAAMRAAAAG----LGHPASPGGSE 82

Query: 390 FGPEGCEERWAEHTGDSPRPLRGR 413
            GP G EE  A   G    P RGR
Sbjct: 83  DGPPGSEEEDAAREGTPGSPGRGR 106


>gi|22547201 zinc finger protein of the cerebellum 4 [Homo sapiens]
          Length = 334

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 10/77 (12%)

Query: 387 PWRFGPEGCEERWAE----------HTGDSPRPLRGRGTGRLWRWGSKERRACGVRAMLP 436
           P+R   EGCE R+A           HT D P   + RG  + +   S  R+   V    P
Sbjct: 233 PFRCEFEGCERRFANSSDRKKHSHVHTSDKPYTCKVRGCDKCYTHPSSLRKHMKVHGRSP 292

Query: 437 RLVSNSGLKRPSCLDLP 453
              S      PS L  P
Sbjct: 293 PPSSGYDSATPSALVSP 309


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,113,295
Number of Sequences: 37866
Number of extensions: 962830
Number of successful extensions: 2844
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2829
Number of HSP's gapped (non-prelim): 38
length of query: 483
length of database: 18,247,518
effective HSP length: 106
effective length of query: 377
effective length of database: 14,233,722
effective search space: 5366113194
effective search space used: 5366113194
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.