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Search of human proteins with 46410931
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46410931 attractin-like 1 [Homo sapiens]
(1379 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46410931 attractin-like 1 [Homo sapiens] 2956 0.0
gi|21450861 attractin isoform 1 [Homo sapiens] 1771 0.0
gi|21450863 attractin isoform 2 [Homo sapiens] 1550 0.0
gi|145701025 multiple EGF-like-domains 8 [Homo sapiens] 222 2e-57
gi|16945972 kelch domain containing 3 [Homo sapiens] 80 1e-14
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 74 1e-12
gi|50659100 regeneration associated muscle protease isoform b [H... 72 3e-12
gi|219842266 usherin isoform B [Homo sapiens] 71 6e-12
gi|219842259 usherin isoform A [Homo sapiens] 71 6e-12
gi|22547221 tolloid-like 1 [Homo sapiens] 70 1e-11
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 69 3e-11
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 69 3e-11
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 69 3e-11
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 69 3e-11
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 68 5e-11
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 68 7e-11
gi|21264602 laminin alpha 5 [Homo sapiens] 67 1e-10
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 66 2e-10
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 66 2e-10
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 65 3e-10
gi|50659098 regeneration associated muscle protease isoform a [H... 64 1e-09
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 63 2e-09
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 63 2e-09
gi|98986457 host cell factor 1 [Homo sapiens] 63 2e-09
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 62 3e-09
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 62 4e-09
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 62 4e-09
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 62 4e-09
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 62 5e-09
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 62 5e-09
>gi|46410931 attractin-like 1 [Homo sapiens]
Length = 1379
Score = 2956 bits (7664), Expect = 0.0
Identities = 1379/1379 (100%), Positives = 1379/1379 (100%)
Query: 1 METGGRARTGTPQPAAPGVWRARPAGGGGGGASSWLLDGNSWLLCYGFLYLALYAQVSQS 60
METGGRARTGTPQPAAPGVWRARPAGGGGGGASSWLLDGNSWLLCYGFLYLALYAQVSQS
Sbjct: 1 METGGRARTGTPQPAAPGVWRARPAGGGGGGASSWLLDGNSWLLCYGFLYLALYAQVSQS 60
Query: 61 KPCERTGSCFSGRCVNSTCLCDPGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCT 120
KPCERTGSCFSGRCVNSTCLCDPGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCT
Sbjct: 61 KPCERTGSCFSGRCVNSTCLCDPGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCT 120
Query: 121 WLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVPEIRGNETVPEV 180
WLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVPEIRGNETVPEV
Sbjct: 121 WLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVPEIRGNETVPEV 180
Query: 181 VTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSGHGKCTTSVSVPSQVYCECDKYWK 240
VTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSGHGKCTTSVSVPSQVYCECDKYWK
Sbjct: 181 VTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSGHGKCTTSVSVPSQVYCECDKYWK 240
Query: 241 GEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFS 300
GEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFS
Sbjct: 241 GEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFS 300
Query: 301 PSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVGTPSRGPLQRYGHSL 360
PSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVGTPSRGPLQRYGHSL
Sbjct: 301 PSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIWNVGTPSRGPLQRYGHSL 360
Query: 361 ALYQENIFMYGGRIETNDGNVTDELWVFNIHSQSWSTKTPTVLGHGQQYAVEGHSAHIME 420
ALYQENIFMYGGRIETNDGNVTDELWVFNIHSQSWSTKTPTVLGHGQQYAVEGHSAHIME
Sbjct: 361 ALYQENIFMYGGRIETNDGNVTDELWVFNIHSQSWSTKTPTVLGHGQQYAVEGHSAHIME 420
Query: 421 LDSRDVVMIIIFGYSAIYGYTSSIQEYHISSNTWLVPETKGAIVQGGYGHTSVYDEITKS 480
LDSRDVVMIIIFGYSAIYGYTSSIQEYHISSNTWLVPETKGAIVQGGYGHTSVYDEITKS
Sbjct: 421 LDSRDVVMIIIFGYSAIYGYTSSIQEYHISSNTWLVPETKGAIVQGGYGHTSVYDEITKS 480
Query: 481 IYVHGGYKALPGNKYGLVDDLYKYEVNTKTWTILKESGFARYLHSAVLINGAMLIFGGNT 540
IYVHGGYKALPGNKYGLVDDLYKYEVNTKTWTILKESGFARYLHSAVLINGAMLIFGGNT
Sbjct: 481 IYVHGGYKALPGNKYGLVDDLYKYEVNTKTWTILKESGFARYLHSAVLINGAMLIFGGNT 540
Query: 541 HNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHSAVVINGSMYIFGGFS 600
HNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHSAVVINGSMYIFGGFS
Sbjct: 541 HNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHSAVVINGSMYIFGGFS 600
Query: 601 SVLLNDILVYKPPNCKAFRDEELCKNAGPGIKCVWNKNHCESWESGNTNNILRAKCPPKT 660
SVLLNDILVYKPPNCKAFRDEELCKNAGPGIKCVWNKNHCESWESGNTNNILRAKCPPKT
Sbjct: 601 SVLLNDILVYKPPNCKAFRDEELCKNAGPGIKCVWNKNHCESWESGNTNNILRAKCPPKT 660
Query: 661 AASDDRCYRYADCASCTANTNGCQWCDDKKCISANSNCSMSVKNYTKCHVRNEQICNKLT 720
AASDDRCYRYADCASCTANTNGCQWCDDKKCISANSNCSMSVKNYTKCHVRNEQICNKLT
Sbjct: 661 AASDDRCYRYADCASCTANTNGCQWCDDKKCISANSNCSMSVKNYTKCHVRNEQICNKLT 720
Query: 721 SCKSCSLNLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRVNSSRENYDNAKLYCYNLS 780
SCKSCSLNLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRVNSSRENYDNAKLYCYNLS
Sbjct: 721 SCKSCSLNLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRVNSSRENYDNAKLYCYNLS 780
Query: 781 GNLASLTTSKEVEFVLDEIQKYTQQKVSPWVGLRKINISYWGWEDMSPFTNTTLQWLPGE 840
GNLASLTTSKEVEFVLDEIQKYTQQKVSPWVGLRKINISYWGWEDMSPFTNTTLQWLPGE
Sbjct: 781 GNLASLTTSKEVEFVLDEIQKYTQQKVSPWVGLRKINISYWGWEDMSPFTNTTLQWLPGE 840
Query: 841 PNDSGFCAYLERAAVAGLKANPCTSMANGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCT 900
PNDSGFCAYLERAAVAGLKANPCTSMANGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCT
Sbjct: 841 PNDSGFCAYLERAAVAGLKANPCTSMANGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCT 900
Query: 901 SNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGW 960
SNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGW
Sbjct: 901 SNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGW 960
Query: 961 CNDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNLCPKEKNYEWSFIQCPACQCNGHS 1020
CNDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNLCPKEKNYEWSFIQCPACQCNGHS
Sbjct: 961 CNDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNLCPKEKNYEWSFIQCPACQCNGHS 1020
Query: 1021 TCINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCSGHANICHLHTGKCFCTT 1080
TCINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCSGHANICHLHTGKCFCTT
Sbjct: 1021 TCINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCSGHANICHLHTGKCFCTT 1080
Query: 1081 KGIKGDQCQLCDSENRYVGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQS 1140
KGIKGDQCQLCDSENRYVGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQS
Sbjct: 1081 KGIKGDQCQLCDSENRYVGNPLRGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQS 1140
Query: 1141 NKNLDISINASNNFNLNITWSVGSTAGTISGEETSIVSKNNIKEYRDSFSYEKFNFRSNP 1200
NKNLDISINASNNFNLNITWSVGSTAGTISGEETSIVSKNNIKEYRDSFSYEKFNFRSNP
Sbjct: 1141 NKNLDISINASNNFNLNITWSVGSTAGTISGEETSIVSKNNIKEYRDSFSYEKFNFRSNP 1200
Query: 1201 NITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWA 1260
NITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWA
Sbjct: 1201 NITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWA 1260
Query: 1261 SRRREQLLRERQQMASRPFASVDVALEVGAEQTEFLRGPLEGAPKPIAIEPCAGNRAAVL 1320
SRRREQLLRERQQMASRPFASVDVALEVGAEQTEFLRGPLEGAPKPIAIEPCAGNRAAVL
Sbjct: 1261 SRRREQLLRERQQMASRPFASVDVALEVGAEQTEFLRGPLEGAPKPIAIEPCAGNRAAVL 1320
Query: 1321 TVFLCLPRGSSGAPPPGQSGLAIASALIDISQQKASDSKDKTSGVRNRKHLSTRQGTCV 1379
TVFLCLPRGSSGAPPPGQSGLAIASALIDISQQKASDSKDKTSGVRNRKHLSTRQGTCV
Sbjct: 1321 TVFLCLPRGSSGAPPPGQSGLAIASALIDISQQKASDSKDKTSGVRNRKHLSTRQGTCV 1379
>gi|21450861 attractin isoform 1 [Homo sapiens]
Length = 1429
Score = 1771 bits (4586), Expect = 0.0
Identities = 818/1341 (60%), Positives = 1021/1341 (76%), Gaps = 36/1341 (2%)
Query: 61 KPCERTGSCFSGRCVNSTCLCDPGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCT 120
+PC G C G C+C GWVG+QCQHC GRF+LT SG++TDGP NYKYKTKCT
Sbjct: 103 RPCVNGGRCNPG---TGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCT 159
Query: 121 WLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVPEIRGNETVPEV 180
WLIEG PN ++RLRFNHFATECSWDH+YVYDGDSIYAPL+A SGLIVPE GNETVPEV
Sbjct: 160 WLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEV 219
Query: 181 VTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSGHGKCTTSVSVPSQVYCECDKYWK 240
V TSGYALLHFFSDAAYNLTGFNI YS + CPNNCSG G+C S S + V CEC + WK
Sbjct: 220 VATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGECKISNSSDT-VECECSENWK 278
Query: 241 GEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFS 300
GEACDIP+C NCG P G C+ + + C C WQGP CS+ VP+ +S+W
Sbjct: 279 GEACDIPHCTDNCGFPHRGICNSSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLK 338
Query: 301 PSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIW-NVGTPSRGPLQRYGHS 359
+ RASHKAV++G MWV+GGY FN+S + MVL Y+L S W + + RYGHS
Sbjct: 339 --LPRASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHS 396
Query: 360 LALYQENIFMYGGRIETNDGNVTDELWVFNIHSQSWSTKTPTVLGHGQQYAVEGHSAHIM 419
LALY++ I+MYGG+I++ GNVT+EL VF+IH++SW TP +QYAV GHSAHI+
Sbjct: 397 LALYKDKIYMYGGKIDST-GNVTNELRVFHIHNESWVLLTPKAK---EQYAVVGHSAHIV 452
Query: 420 ELDSRDVVMIIIFGYSAIYGYTSSIQEYHISSNTWLVPETKGAIVQGGYGHTSVYDEITK 479
L + VVM++IFG+ +YGY S++QEY + NTW + T+GA+VQGGYGH+SVYD T+
Sbjct: 453 TLKNGRVVMLVIFGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDHRTR 512
Query: 480 SIYVHGGYKALPGNKYGLVDDLYKYEVNTKTWTILKESGFARYLHSAVLINGAMLIFGGN 539
++YVHGGYKA NKY L DDLY+Y+V+T+ WTILK+S F RYLH+AV+++G ML+FGGN
Sbjct: 513 ALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTILKDSRFFRYLHTAVIVSGTMLVFGGN 572
Query: 540 THNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHSAVVINGSMYIFGGF 599
THNDTS+S+GAKCFS+DF+AYDIACD W +LP+P+LH DVNRFGHSAV+ N +MY+FGGF
Sbjct: 573 THNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGF 632
Query: 600 SSVLLNDILVYKPPNCKAFRDEELCKNAGPGIKCVWN--KNHCESWE--SGNTNNILRAK 655
+S+LL+DILV+ C A R E C AGPGI+CVWN + C SW + L+++
Sbjct: 633 NSLLLSDILVFTSEQCDAHRSEAACLAAGPGIRCVWNTGSSQCISWALATDEQEEKLKSE 692
Query: 656 CPPKTAASDDRCYRYADCASCTANTNGCQWCDDKKCISANSNCS---MSVKNYTKCHVRN 712
C K DRC ++ DC SCTANTN C WC+D C+ N +CS +S+ Y C N
Sbjct: 693 CFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDH-CVPRNHSCSEGQISIFRYENCPKDN 751
Query: 713 EQI-CNKLTSCKSCSLNLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRVNSSRENYDN 771
CNK TSC+SC+L+ NCQW+ R QEC ALP ++CG GW +G++CL++ +++ENYDN
Sbjct: 752 PMYYCNKKTSCRSCALDQNCQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKENYDN 811
Query: 772 AKLYCYNLSGNLASLTTSKEVEFVLDEI------QKYTQQKVSPWVGLRKINISYWGWED 825
AKL+C N + LASLTT K+VEFVL ++ Q ++ ++PWVGLRKIN+SYW WED
Sbjct: 812 AKLFCRNHNALLASLTTQKKVEFVLKQLRIMQSSQSMSKLTLTPWVGLRKINVSYWCWED 871
Query: 826 MSPFTNTTLQWLPGEPNDSGFCAYLERAAVAGLKANPCTSMANGLVCEKPVVSPNQNARP 885
MSPFTN+ LQW+P EP+D+GFC L + GLKA C + NG VCE+P N +A+
Sbjct: 872 MSPFTNSLLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPA---NHSAKQ 928
Query: 886 CKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQT-ATCSPQNCS 944
C+ PC+LRT+C +CTS ECMWCS+ K+CVDSNAY+ SFP+GQC+EW T +TC P+NCS
Sbjct: 929 CRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSTCPPENCS 988
Query: 945 GLRTCGQCLEQPGCGWCNDPSNTGRGHCIEGSSRGPMKL-----IGMHHSEMVLDTNLCP 999
G TC CLEQPGCGWC DPSNTG+G CIEGS +GP+K+ G + + +L++++C
Sbjct: 989 GYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCL 1048
Query: 1000 KEKNYEWSFIQCPACQCNGHSTCINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTA 1059
++ Y WSFI CPACQCNGHS CIN ++CE+C+NLTTGK C+ C+ G+YGDPTNGG+C
Sbjct: 1049 EDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQP 1108
Query: 1060 CTCSGHANICHLHTGKCFCTTKGIKGDQCQLCDSENRYVGNPLRGTCYYSLLIDYQFTFS 1119
C C+GHA++C+ +TGKCFCTTKG+KGD+CQLC+ ENRY GNPLRGTCYY+LLIDYQFTFS
Sbjct: 1109 CKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLRGTCYYTLLIDYQFTFS 1168
Query: 1120 LLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSVGSTAGTISGEETSIVSK 1179
L QEDDR++TAINF+A P++ N++LD+ INAS NFNLNITW+ +AGT +GEE +VSK
Sbjct: 1169 LSQEDDRYYTAINFVATPDEQNRDLDMFINASKNFNLNITWAASFSAGTQAGEEMPVVSK 1228
Query: 1180 NNIKEYRDSFSYEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQHNTIMDLVQFFVTFFS 1239
NIKEY+DSFS EKF+FR++PNITF+VYVSNF+WPIKIQIAFSQH+ MDLVQFFVTFFS
Sbjct: 1229 TNIKEYKDSFSNEKFDFRNHPNITFFVYVSNFTWPIKIQIAFSQHSNFMDLVQFFVTFFS 1288
Query: 1240 CFLSLLLVAAVVWKIKQTCWASRRREQLLRERQQMASRPFASVDVALEVGAEQTEFLRGP 1299
CFLSLLLVAAVVWKIKQ+CWASRRREQLLRE QQMASRPFASV+VALE E + + G
Sbjct: 1289 CFLSLLLVAAVVWKIKQSCWASRRREQLLREMQQMASRPFASVNVALETDEEPPDLIGGS 1348
Query: 1300 LEGAPKPIAIEPCAGNRAAVLTVFLCLPRGSSGAPPPGQSGLAIASALIDISQQKASDSK 1359
++ PKPIA+EPC GN+AAVL+VF+ LPRG G PPPGQSGLA+ASAL+DISQQ K
Sbjct: 1349 IKTVPKPIALEPCFGNKAAVLSVFVRLPRGLGGIPPPGQSGLAVASALVDISQQMPIVYK 1408
Query: 1360 DKTSGVRNRKHLSTRQ-GTCV 1379
+K+ VRNRK Q GTC+
Sbjct: 1409 EKSGAVRNRKQQPPAQPGTCI 1429
>gi|21450863 attractin isoform 2 [Homo sapiens]
Length = 1272
Score = 1550 bits (4014), Expect = 0.0
Identities = 704/1184 (59%), Positives = 892/1184 (75%), Gaps = 35/1184 (2%)
Query: 61 KPCERTGSCFSGRCVNSTCLCDPGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCT 120
+PC G C G C+C GWVG+QCQHC GRF+LT SG++TDGP NYKYKTKCT
Sbjct: 103 RPCVNGGRCNPG---TGQCVCPAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCT 159
Query: 121 WLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVPEIRGNETVPEV 180
WLIEG PN ++RLRFNHFATECSWDH+YVYDGDSIYAPL+A SGLIVPE GNETVPEV
Sbjct: 160 WLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEV 219
Query: 181 VTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSGHGKCTTSVSVPSQVYCECDKYWK 240
V TSGYALLHFFSDAAYNLTGFNI YS + CPNNCSG G+C S S + V CEC + WK
Sbjct: 220 VATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGECKISNSSDT-VECECSENWK 278
Query: 241 GEACDIPYCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFS 300
GEACDIP+C NCG P G C+ + + C C WQGP CS+ VP+ +S+W
Sbjct: 279 GEACDIPHCTDNCGFPHRGICNSSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLK 338
Query: 301 PSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIW-NVGTPSRGPLQRYGHS 359
+ RASHKAV++G MWV+GGY FN+S + MVL Y+L S W + + RYGHS
Sbjct: 339 --LPRASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHS 396
Query: 360 LALYQENIFMYGGRIETNDGNVTDELWVFNIHSQSWSTKTPTVLGHGQQYAVEGHSAHIM 419
LALY++ I+MYGG+I++ GNVT+EL VF+IH++SW TP +QYAV GHSAHI+
Sbjct: 397 LALYKDKIYMYGGKIDST-GNVTNELRVFHIHNESWVLLTPKAK---EQYAVVGHSAHIV 452
Query: 420 ELDSRDVVMIIIFGYSAIYGYTSSIQEYHISSNTWLVPETKGAIVQGGYGHTSVYDEITK 479
L + VVM++IFG+ +YGY S++QEY + NTW + T+GA+VQGGYGH+SVYD T+
Sbjct: 453 TLKNGRVVMLVIFGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDHRTR 512
Query: 480 SIYVHGGYKALPGNKYGLVDDLYKYEVNTKTWTILKESGFARYLHSAVLINGAMLIFGGN 539
++YVHGGYKA NKY L DDLY+Y+V+T+ WTILK+S F RYLH+AV+++G ML+FGGN
Sbjct: 513 ALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTILKDSRFFRYLHTAVIVSGTMLVFGGN 572
Query: 540 THNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHSAVVINGSMYIFGGF 599
THNDTS+S+GAKCFS+DF+AYDIACD W +LP+P+LH DVNRFGHSAV+ N +MY+FGGF
Sbjct: 573 THNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGF 632
Query: 600 SSVLLNDILVYKPPNCKAFRDEELCKNAGPGIKCVWN--KNHCESWE--SGNTNNILRAK 655
+S+LL+DILV+ C A R E C AGPGI+CVWN + C SW + L+++
Sbjct: 633 NSLLLSDILVFTSEQCDAHRSEAACLAAGPGIRCVWNTGSSQCISWALATDEQEEKLKSE 692
Query: 656 CPPKTAASDDRCYRYADCASCTANTNGCQWCDDKKCISANSNCS---MSVKNYTKCHVRN 712
C K DRC ++ DC SCTANTN C WC+D C+ N +CS +S+ Y C N
Sbjct: 693 CFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDH-CVPRNHSCSEGQISIFRYENCPKDN 751
Query: 713 EQI-CNKLTSCKSCSLNLNCQWDQRQQECQALPAHLCGEGWSHIGDACLRVNSSRENYDN 771
CNK TSC+SC+L+ NCQW+ R QEC ALP ++CG GW +G++CL++ +++ENYDN
Sbjct: 752 PMYYCNKKTSCRSCALDQNCQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKENYDN 811
Query: 772 AKLYCYNLSGNLASLTTSKEVEFVLDEI------QKYTQQKVSPWVGLRKINISYWGWED 825
AKL+C N + LASLTT K+VEFVL ++ Q ++ ++PWVGLRKIN+SYW WED
Sbjct: 812 AKLFCRNHNALLASLTTQKKVEFVLKQLRIMQSSQSMSKLTLTPWVGLRKINVSYWCWED 871
Query: 826 MSPFTNTTLQWLPGEPNDSGFCAYLERAAVAGLKANPCTSMANGLVCEKPVVSPNQNARP 885
MSPFTN+ LQW+P EP+D+GFC L + GLKA C + NG VCE+P N +A+
Sbjct: 872 MSPFTNSLLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPA---NHSAKQ 928
Query: 886 CKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQT-ATCSPQNCS 944
C+ PC+LRT+C +CTS ECMWCS+ K+CVDSNAY+ SFP+GQC+EW T +TC P+NCS
Sbjct: 929 CRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSTCPPENCS 988
Query: 945 GLRTCGQCLEQPGCGWCNDPSNTGRGHCIEGSSRGPMKL-----IGMHHSEMVLDTNLCP 999
G TC CLEQPGCGWC DPSNTG+G CIEGS +GP+K+ G + + +L++++C
Sbjct: 989 GYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCL 1048
Query: 1000 KEKNYEWSFIQCPACQCNGHSTCINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTA 1059
++ Y WSFI CPACQCNGHS CIN ++CE+C+NLTTGK C+ C+ G+YGDPTNGG+C
Sbjct: 1049 EDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQP 1108
Query: 1060 CTCSGHANICHLHTGKCFCTTKGIKGDQCQLCDSENRYVGNPLRGTCYYSLLIDYQFTFS 1119
C C+GHA++C+ +TGKCFCTTKG+KGD+CQLC+ ENRY GNPLRGTCYY+LLIDYQFTFS
Sbjct: 1109 CKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLRGTCYYTLLIDYQFTFS 1168
Query: 1120 LLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSVGSTAGTISGEETSIVSK 1179
L QEDDR++TAINF+A P++ N++LD+ INAS NFNLNITW+ +AGT +GEE +VSK
Sbjct: 1169 LSQEDDRYYTAINFVATPDEQNRDLDMFINASKNFNLNITWAASFSAGTQAGEEMPVVSK 1228
Query: 1180 NNIKEYRDSFSYEKFNFRSNPNITFYVYVSNFSWPIKIQIAFSQ 1223
NIKEY+DSFS EKF+FR++PNITF+VYVSNF+WPIKIQ+ Q
Sbjct: 1229 TNIKEYKDSFSNEKFDFRNHPNITFFVYVSNFTWPIKIQVQTEQ 1272
>gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]
Length = 2778
Score = 222 bits (565), Expect = 2e-57
Identities = 173/630 (27%), Positives = 265/630 (42%), Gaps = 74/630 (11%)
Query: 87 GDQCQHCQG-RFKLTEPSGYLTDGPINYKYKTKCTWLIEG-YPNAVLRLRFNHFATECSW 144
G + C+G R L E G++TDG NY C WLIE P + L F TEC++
Sbjct: 24 GARAGDCKGQRQVLREAPGFVTDGAGNYSVNGNCEWLIEAPSPQHRILLDFLFLDTECTY 83
Query: 145 DHMYVYDGDSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNI 204
D+++VYDGDS PL+A LSG P P + +SG LLH FSDA YNL GFN
Sbjct: 84 DYLFVYDGDSPRGPLLASLSGSTRP--------PPIEASSGKMLLHLFSDANYNLLGFNA 135
Query: 205 FYSINSCPNNCSGHGKCTTSVSVPSQVYCECDKYWKGEACDIPYCKANCGSPDHGYCDLT 264
+ + CP C HG+C P V C C+ W G C + C A CGS HG C +
Sbjct: 136 SFRFSLCPGGCQSHGQCQ-----PPGV-CACEPGWGGPDCGLQECSAYCGS--HGTC-AS 186
Query: 265 GEKLCVCNDSWQGPDCSLNVPSTESYWILPNVK----PFSPSVGRASHKAVLHGKFMWVI 320
C C + G C L++ + NV FS +G A G + V
Sbjct: 187 PLGPCRCEPGFLGRACDLHLWENQGAGWWHNVSARDPAFSARIGAAGAFLSPPG-LLAVF 245
Query: 321 GGYTFNYSSFQMVLNYNLESSIWNVGTPSRGPLQRYGHSLALYQENIFMYGGRIETNDGN 380
GG N + +VL YN ++ W S P R+ H + ++ + GG E DG+
Sbjct: 246 GGQDLNNALGDLVL-YNFSANTWESWDLSPAPAARHSHVAVAWAGSLVLMGG--ELADGS 302
Query: 381 VTDELWVFN-IHSQSWSTKTPTVLGHGQQYAVEGHSAHIMELDSRDVVMIIIFGYSAIYG 439
+T+++W F+ + W P + GH+A +++ DV + + G +
Sbjct: 303 LTNDVWAFSPLGRGHWELLAPPASSSSGPPGLAGHAAALVD----DVWLYVSGGRTPHDL 358
Query: 440 YTSSIQEYHISSNT---WLVPETKGAIVQGGYGHTSVYDEITKSIYVHGGYKALPGNKYG 496
++S + + + S + W G GH+ V+ ++++ VHGG++
Sbjct: 359 FSSGLFRFRLDSTSGGYWEQVIPAGGRPPAATGHSMVFHAPSRALLVHGGHRPSTARFSV 418
Query: 497 LVDDLYKYEVNTKTWTILK-----ESGFARYLHSAVLINGAMLIFGGNTHNDTSLSNGAK 551
V+ + V+ WT LK + R H+A ++ M+++GGN H K
Sbjct: 419 RVNSTELFHVDRHVWTTLKGRDGLQGPRERAFHTASVLGNYMVVYGGNVHTH---YQEEK 475
Query: 552 CFSADFLAYDIACDEWKI--------LPKPNLHRDVNRFGHSAVVINGS-MYIFGGFSSV 602
C+ Y + C +W P+ R+ H A V+ GS + + GG+S
Sbjct: 476 CYEDGIFFYHLGCHQWVSGAELAPPGTPEGRAAPPSGRYSHVAAVLGGSVLLVAGGYSGR 535
Query: 603 LLNDILVYKPP--------------NCKAFRDEELCKNAGPGIKCVWNKNHCESWESGNT 648
D++ YK P C + D +C +C W + C++ T
Sbjct: 536 PRGDLMAYKVPPFVFQAPAPDYHLDYCSMYTDHSVCSR---DPECSWCQGACQAAPPPGT 592
Query: 649 NNILRAKCPPKTAASDDRCYRYADCASCTA 678
CP + R DC +C A
Sbjct: 593 P---LGACPAASCLGLGRL--LGDCQACLA 617
Score = 177 bits (448), Expect = 8e-44
Identities = 273/1206 (22%), Positives = 429/1206 (35%), Gaps = 298/1206 (24%)
Query: 61 KPCE-------RTGSC--FSGRCV------NSTC-LCDPGWVGD-----QC-QHCQGRFK 98
+PC+ R G C SG C + C LC PG+ GD C + C GR
Sbjct: 1142 RPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRAL 1201
Query: 99 LTEPS-----------------GYLTDGP-INYKYKTKCTWLIEGY-------PNAV--- 130
LT S G GP ++Y C W++ P +
Sbjct: 1202 LTNVSSVALGSRRVGGLLPPGGGAARAGPGLSY-----CVWVVSATEELQPCAPGTLCPP 1256
Query: 131 LRLRFN-HFATECSWDHMYVYDGDSIYAPLIAVLS--GLIVPEIRGNETVPEVVTT-SGY 186
L L F+ +T C+ ++ +DG + V S LI P V SG
Sbjct: 1257 LTLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGL 1316
Query: 187 ALLHFFSDAAYNLTGFNIFYSINSC----PNNCSGHGKCTTSVSVPSQVYCECDKYWKGE 242
+LH+ ++ + + GFN C P +C +C C C + W G
Sbjct: 1317 LVLHWEANGSSSW-GFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGP 1375
Query: 243 ACDIPYCKANCGS-PDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYW-ILPNVKPFS 300
C + C NC + G C+ + +C+C + + GPDC+ + + W L + + +
Sbjct: 1376 HCRMALCPENCNAHTGAGTCNQS-LGVCICAEGFGGPDCATKLDGGQLVWETLMDSRLSA 1434
Query: 301 PSVGRASHK---AVLHGK--FMWVIGGYTFNYSSFQMVLNYNLESSIWNV-------GTP 348
+ R H+ ++ G +W+ GG + Y++ W G P
Sbjct: 1435 DTASRFLHRLGHTMVDGPDATLWMFGGLGLPQGLLGNLYRYSVSERRWTQMLAGAEDGGP 1494
Query: 349 SRGPLQRYGHSLALYQEN---IFMYGGRIETNDGNVTDELWVFNIHSQSW-STKTPTVLG 404
GP R H+ A +++ GG G VT + WV N+ + W K P +
Sbjct: 1495 --GPSPRSFHAAAYVPAGRGAMYLLGG---LTAGGVTRDFWVLNLTTLQWRQEKAPQTV- 1548
Query: 405 HGQQYAVEGHSAHIMELDSRDVVMIIIFGYSAIYGYTSSIQEYHISSNTWLVPETKGAIV 464
+ AV GH+ R + ++++ GYS G+ + EY +++ TW+ G
Sbjct: 1549 --ELPAVAGHTLTAR----RGLSLLLVGGYSPENGFNQQLLEYQLATGTWVSGAQSGTPP 1602
Query: 465 QGGYGHTSVYDEITKSIYVHGGYK-----ALPGNKYGLVDDLYKYEVNTKTWTILKES-- 517
G YGH++VY E T S+YV GG++ A P +LY +TW++L S
Sbjct: 1603 TGLYGHSAVYHEATDSLYVFGGFRFHVELAAPS------PELYSLHCPDRTWSLLAPSQG 1656
Query: 518 ---------------------------GFARYLHSAVLINGAMLIFGG-----NTH---- 541
GF R + + + A+ GG + H
Sbjct: 1657 AKRDRMRNVRGSSRGLGQVPGEQPGSWGF-REVRKKMALWAALAGTGGFLEEISPHLKEP 1715
Query: 542 -----------NDTSLSNGAKCFSADF----LAYDIACDEWKILPKPNLHRDVN------ 580
DT + G + +F L Y + C+ W + P+L R +
Sbjct: 1716 RPRLFHASALLGDTMVVLGGRSDPDEFSSDVLLYQVNCNAWLL---PDLTRSASVGPPME 1772
Query: 581 -RFGHSAVVINGSMYIFGGFSSVLLNDI--LVYKPPNCKAFRDEELCKNAGPGIKCVWNK 637
H+ + +YI GGF V L + L P C+ E C +G C W
Sbjct: 1773 ESVAHAVAAVGSRLYISGGFGGVALGRLLALTLPPDPCRLLSSPEACNQSG---ACTWCH 1829
Query: 638 NHCESWESGNTNNILRAKCPPKTAASDDRCYRYADCASC-------------TANTNGCQ 684
C S + + + C P S + C R C+ C A+T C+
Sbjct: 1830 GACLSGDQAHRLGCGGSPCSP-MPRSPEECRRLRTCSECLARHPRTLQPGDGEASTPRCK 1888
Query: 685 W---CDDKKCISANSNCSMSVKNYTKCHVRNEQI-----CNK----LTSCKSCSLNLNCQ 732
W C + CI N +C+ + C + ++ C++ C+ C+ C
Sbjct: 1889 WCTNCPEGACIGRNGSCT----SENDCRINQREVFWAGNCSEAACGAADCEQCTREGKCM 1944
Query: 733 WD---QRQQECQALPAHLCGEGWSHIGDACLRVNSSRENYDNAKLYC---YNLSGNLASL 786
W +R E + + + W+ + L V S + L C +L N S
Sbjct: 1945 WTRQFKRTGETRRILSVQPTYDWTCFSHSLLNV-SPMPVESSPPLPCPTPCHLLPNCTSC 2003
Query: 787 TTSKEVEFVLDEI--QKYTQQKVSPWVGLRKINISYWGWEDMSPFTNTTLQWLPGEPNDS 844
SK + QQ +SP SY M+ L+ G + S
Sbjct: 2004 LDSKGADGGWQHCVWSSSLQQCLSP---------SYLPLRCMAGGCGRLLR---GPESCS 2051
Query: 845 GFCAYLERAAVAGLKANPCTSMA-----NGLVCEKPVVSPNQNARPCKKP--------CS 891
CA + A+ L+ C A G C + +S ++ C +P C
Sbjct: 2052 LGCAQATQCALC-LRRPHCGWCAWGGQDGGGRCMEGGLSGPRDGLTCGRPGASWAFLSCP 2110
Query: 892 LRTSCSNCTSNGMECMWCSSTKRCVDS-NAYIISFPYGQCLEWQTATCSPQNCSGLRTCG 950
C+N + C+ T+ C D + Y S G ++ T C P C
Sbjct: 2111 PEDECANGHHD------CNETQNCHDQPHGYECSCKTGYTMDNMTGLCRP-------VCA 2157
Query: 951 QCLEQPGC--GWCNDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNLCPKEKNYEWSF 1008
Q GC G C +P HC R +G + C E
Sbjct: 2158 Q-----GCVNGSCVEPD-----HC-----RCHFGFVGRN----------CSTE------- 2185
Query: 1009 IQCPACQCNGHSTCIN---NNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTAC--TCS 1063
C+CN HS C + C C+N T G C+ C+P + G GG C C C
Sbjct: 2186 -----CRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCR 2240
Query: 1064 GHANIC 1069
G+++IC
Sbjct: 2241 GNSHIC 2246
Score = 105 bits (261), Expect = 4e-22
Identities = 57/191 (29%), Positives = 84/191 (43%), Gaps = 23/191 (12%)
Query: 886 CKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSP---QN 942
C CS R +C +C +N +C WC ST C AY+ +P+G C W + S ++
Sbjct: 879 CPPLCSQRLTCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDSVHSEPRCRS 938
Query: 943 CSGLRTCGQCLEQPGCGWCNDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNLCPKEK 1002
C G TC +CL+ CGWC + N G C++G GP L G + S V + P
Sbjct: 939 CDGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGP--LGGGNCSLWVGEGLGLPVAL 996
Query: 1003 NYEWSFIQCP--------ACQCNGHSTCINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNG 1054
W++ +CP +C+ +TC+N + +C C GY GD +
Sbjct: 997 PARWAYARCPDVDECRLGLARCHPRATCLNTPLSYEC----------HCQRGYQGDGISH 1046
Query: 1055 GQCTACTCSGH 1065
T GH
Sbjct: 1047 CNRTCLEDCGH 1057
Score = 84.0 bits (206), Expect = 9e-16
Identities = 70/256 (27%), Positives = 99/256 (38%), Gaps = 33/256 (12%)
Query: 864 TSMANGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCT-SNGME-----CMWCSSTKRCVD 917
T ++ L+ P+ + PC PC L +C++C S G + C+W SS ++C+
Sbjct: 1968 TCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLS 2027
Query: 918 SNAYIISFPYGQC--LEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGRGHCIEG 975
+ + G C L +CS C+ C CL +P CGWC G G C+EG
Sbjct: 2028 PSYLPLRCMAGGCGRLLRGPESCS-LGCAQATQCALCLRRPHCGWCAWGGQDGGGRCMEG 2086
Query: 976 SSRGPMKLIGMHHSEMVLDTNLCPKEKNYEWSFIQC-PACQC-NGHSTCINNNVCEQCKN 1033
GP D C + W+F+ C P +C NGH C N + C +
Sbjct: 2087 GLSGPR------------DGLTCGR-PGASWAFLSCPPEDECANGHHDC---NETQNCHD 2130
Query: 1034 LTTGKQCQDCMPGYYGDPTNGGQCTACTCSGHANICHLHTGKCFCTTKGIKGDQCQL--- 1090
G +C C GY D G C G N + C C G G C
Sbjct: 2131 QPHGYEC-SCKTGYTMDNMT-GLCRPVCAQGCVNGSCVEPDHCRCHF-GFVGRNCSTECR 2187
Query: 1091 CDSENRYVGNPLRGTC 1106
C+ + G R C
Sbjct: 2188 CNRHSECAGVGARDHC 2203
Score = 67.4 bits (163), Expect = 9e-11
Identities = 35/101 (34%), Positives = 51/101 (50%), Gaps = 10/101 (9%)
Query: 1014 CQCNGHSTCINNN--VCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCSGHAN---- 1067
C C+ HS C C++C++ T G+ C+ C PG +G+ T C C C+GH +
Sbjct: 1096 CGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGHGDPRRG 1155
Query: 1068 ICHLHTGKCFCTTKGIKGDQCQLCDSENRYVGNP-LRGTCY 1107
C +G CFC +G CQLC Y G+P G+C+
Sbjct: 1156 HCDNLSGLCFCQDH-TEGAHCQLCSP--GYYGDPRAGGSCF 1193
Score = 57.8 bits (138), Expect = 7e-08
Identities = 49/173 (28%), Positives = 65/173 (37%), Gaps = 48/173 (27%)
Query: 1221 FSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWASRRREQLLRERQQMASRPFA 1280
F Q +DL FF FFSCF L + ++WK KQ + + + L+E +MASRPFA
Sbjct: 2572 FRQDQAHIDLFVFFSVFFSCFFLFLSLCVLLWKAKQALDQRQEQRRHLQEMTKMASRPFA 2631
Query: 1281 SVDVAL------------EVGAEQTEFLR-----------------GPLEGA-------- 1303
V V G F R GP+ G
Sbjct: 2632 KVTVCFPPDPTAPASAWKPAGLPPPAFRRSEPFLAPLLLTGAGGPWGPMGGGCCPPAIPA 2691
Query: 1304 ------PKPIAIEPCAGNRAAVLTVFLCLPRGSSGAPPPGQSGLAIASALIDI 1350
PI +EP A V T+ L LP G P +G + SAL+ +
Sbjct: 2692 TTAGLRAGPITLEPTEDGMAGVATLLLQLPGG-----PHAPNGACLGSALVTL 2739
Score = 55.8 bits (133), Expect = 3e-07
Identities = 28/61 (45%), Positives = 31/61 (50%), Gaps = 6/61 (9%)
Query: 1011 CPACQCNGHST-----CINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCSGH 1065
C CQCNGH C N + C++ T G CQ C PGYYGDP GG C C G
Sbjct: 1141 CRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFR-ECGGR 1199
Query: 1066 A 1066
A
Sbjct: 1200 A 1200
Score = 39.3 bits (90), Expect = 0.026
Identities = 34/139 (24%), Positives = 53/139 (38%), Gaps = 36/139 (25%)
Query: 942 NCSGLRTCGQCLEQPGCGWCNDPS----NTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNL 997
+C+ +C CL GCGWC + G HC + + G S +VL L
Sbjct: 780 SCTSYSSCLGCLADQGCGWCLTSATCHLRQGGAHCGDDGAGG---------SLLVLVPTL 830
Query: 998 CP--KEKNYEWSFIQCPACQCNGHSTCINNNVC-------------EQCKNLTTGK-QCQ 1041
CP +E + Q P C+ + ++ + C E+C L + + C+
Sbjct: 831 CPLCEEHRDCHACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECPPLCSQRLTCE 890
Query: 1042 DCMPGYYGDPTNGGQCTAC 1060
DC+ N QC C
Sbjct: 891 DCL-------ANSSQCAWC 902
Score = 37.7 bits (86), Expect = 0.077
Identities = 26/89 (29%), Positives = 32/89 (35%), Gaps = 14/89 (15%)
Query: 201 GFNIFYSINSCPNNCSGHGKCTTSVSVPSQVYCECDKYWKGE--------ACDIPYCKAN 252
G I + +C +C GHG C S P C CD W + P C +
Sbjct: 1041 GDGISHCNRTCLEDC-GHGVC----SGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRD 1095
Query: 253 CGSPDHGYCDLTGEKLC-VCNDSWQGPDC 280
CG H +C G C C D G C
Sbjct: 1096 CGCSFHSHCRKRGPGFCDECQDWTWGEHC 1124
Score = 37.0 bits (84), Expect = 0.13
Identities = 19/66 (28%), Positives = 25/66 (37%), Gaps = 18/66 (27%)
Query: 1010 QCPACQCNGHS-----------TCINNNVCEQCKNLTTGK-------QCQDCMPGYYGDP 1051
+C CQCNGH+ C NN C+ + QC C ++G P
Sbjct: 2309 KCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQCAKCRESFHGSP 2368
Query: 1052 TNGGQC 1057
G QC
Sbjct: 2369 LGGQQC 2374
Score = 33.5 bits (75), Expect = 1.4
Identities = 33/155 (21%), Positives = 56/155 (36%), Gaps = 34/155 (21%)
Query: 607 ILVYKPPNCKAFRDEELCKNAGPGIKCVWNKNHCESWES-----GNTNNILRA--KCPPK 659
+LV P C + C C W+++ ++ G L++ +CPP
Sbjct: 823 LLVLVPTLCPLCEEHRDCHACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECPPL 882
Query: 660 TAASDDRCYRYADCASCTANTNGCQWCDDKKCISANSNCSMSVKNYTK-----CHVRNEQ 714
C + C C AN++ C WC + C + + C ++
Sbjct: 883 -------CSQRLTCEDCLANSSQCAWC------QSTHTCFLFAAYLARYPHGGCRGWDDS 929
Query: 715 ICNKLTSCKSCSLNLNCQWDQRQQECQALPAHLCG 749
+ ++ C+SC L C EC L +H CG
Sbjct: 930 VHSE-PRCRSCDGFLTC------HEC--LQSHECG 955
>gi|16945972 kelch domain containing 3 [Homo sapiens]
Length = 382
Score = 80.1 bits (196), Expect = 1e-14
Identities = 67/276 (24%), Positives = 117/276 (42%), Gaps = 27/276 (9%)
Query: 351 GPLQRYGHSLALYQENIFMYGGRIETNDGNVTDEL--WVFNIHSQSWSTKTPTVLG--HG 406
GP +R H+ ++ +GG D ++ +FN S W TK P V G
Sbjct: 11 GP-RRVNHAAVAVGHRVYSFGGYCSGEDYETLRQIDVHIFNAVSLRW-TKLPPVKSAIRG 68
Query: 407 QQ----YAVEGHSAHIMELDSRDVVMIIIFGYSAIYGYTSSIQEYHISSNTWLVPETKGA 462
Q Y GHS ++ D +++ G + G + + + ++++ W P G
Sbjct: 69 QAPVVPYMRYGHSTVLI-----DDTVLLWGGRNDTEGACNVLYAFDVNTHKWFTPRVSGT 123
Query: 463 IVQGGYGHTSVYDEITKSIYVHGGYKALPGNKYGLVDDLYKYEVNTKTWTILKESGFA-- 520
+ GH++ + K +Y+ GGY+ +D++K + +T TWT++ G
Sbjct: 124 VPGARDGHSACV--LGKIMYIFGGYEQQADC---FSNDIHKLDTSTMTWTLICTKGSPAR 178
Query: 521 -RYLHSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDV 579
R HSA ++ M +FGG + + + +D + W P P
Sbjct: 179 WRDFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCP-PTPVLPE 237
Query: 580 NRFGHSAVVINGSMYIFGGFSSVL---LNDILVYKP 612
R HSA NG +YIFGG+++ L +D+ + P
Sbjct: 238 GRRSHSAFGYNGELYIFGGYNARLNRHFHDLWKFNP 273
Score = 64.7 bits (156), Expect = 6e-10
Identities = 68/258 (26%), Positives = 111/258 (43%), Gaps = 39/258 (15%)
Query: 305 RASHKAVLHGKFMWVIGGYTF--NYSSFQM--VLNYNLESSIWNVGTPSRG--------- 351
R +H AV G ++ GGY +Y + + V +N S W P +
Sbjct: 14 RVNHAAVAVGHRVYSFGGYCSGEDYETLRQIDVHIFNAVSLRWTKLPPVKSAIRGQAPVV 73
Query: 352 PLQRYGHSLALYQENIFMYGGRIETNDGNVTDELWVFNIHSQSWSTKTPTVLGHGQQYAV 411
P RYGHS L + + ++GGR +T + L+ F++++ W TP V G A
Sbjct: 74 PYMRYGHSTVLIDDTVLLWGGRNDTE--GACNVLYAFDVNTHKWF--TPRVSG-TVPGAR 128
Query: 412 EGHSAHIMELDSRDVVMIIIFGYSAIYG-YTSSIQEYHISSNTWLVPETKGAIVQGGYGH 470
+GHSA ++ +M I GY +++ I + S+ TW + TKG+ + H
Sbjct: 129 DGHSACVL-----GKIMYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWRDFH 183
Query: 471 TSVYDEITKSIYVHGG----YKALPGNKYGLVDDLYKYEVNTKTW------TILKESGFA 520
++ + +YV GG + N + + ++ T+ W +L E
Sbjct: 184 SATM--LGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTPVLPE---G 238
Query: 521 RYLHSAVLINGAMLIFGG 538
R HSA NG + IFGG
Sbjct: 239 RRSHSAFGYNGELYIFGG 256
Score = 34.7 bits (78), Expect = 0.65
Identities = 39/156 (25%), Positives = 61/156 (39%), Gaps = 16/156 (10%)
Query: 258 HGYCDLTGEKLCVCNDSWQGPDCSLN----VPSTESYWILPNVKPFSPSVGRASHKAVLH 313
H C L G+ + + Q DC N + ++ W L K SP+ R H A +
Sbjct: 131 HSACVL-GKIMYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTKG-SPARWRDFHSATML 188
Query: 314 GKFMWVIGGYTFNYSSF--------QMVLNYNLESSIWNVGTPSRG-PLQRYGHSLALYQ 364
G M+V GG + F + ++ + W P+ P R HS Y
Sbjct: 189 GSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTPVLPEGRRSHSAFGYN 248
Query: 365 ENIFMYGGRIETNDGNVTDELWVFNIHSQSWSTKTP 400
++++GG + + D LW FN S +W P
Sbjct: 249 GELYIFGGYNARLNRHFHD-LWKFNPVSFTWKKIEP 283
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 73.6 bits (179), Expect = 1e-12
Identities = 37/103 (35%), Positives = 52/103 (50%), Gaps = 14/103 (13%)
Query: 1011 CPACQCNGHST-CINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNG--GQCTACTC----- 1062
C C+C+GH+ C + VC C + TTG C+ C+PG+YG+P+ G G C C C
Sbjct: 739 CQPCECHGHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIA 798
Query: 1063 -SGHANICHLHTGK---CFCTTKGIKGDQCQLCDSENRYVGNP 1101
+ + CHL+ G C G G C+ C + Y GNP
Sbjct: 799 SNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERC--ADGYYGNP 839
Score = 65.5 bits (158), Expect = 3e-10
Identities = 56/225 (24%), Positives = 75/225 (33%), Gaps = 50/225 (22%)
Query: 888 KPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNC---- 943
+PC + C +G+ C+ C+ V + F YG+ C P C
Sbjct: 740 QPCECHGHAAECNVHGV-CIACAHNTTGVHCEQCLPGF-YGEPSRGTPGDCQPCACPLTI 797
Query: 944 SGLRTCGQCLEQPG----CGWCNDPSNTGRG--HCIEGSSRGPMKLIGMHHSEMVLDTNL 997
+ C G C WC P +G C +G P
Sbjct: 798 ASNNFSPTCHLNDGDEVVCDWCA-PGYSGAWCERCADGYYGNPT---------------- 840
Query: 998 CPKEKNYEWSFIQCPACQCNG--------HSTCINNNVCEQCKNLTTGKQCQDCMPGYYG 1049
P E C C C+G H + C +C T G C+ C G+YG
Sbjct: 841 VPGES--------CVPCDCSGNVDPSEAGHCDSVTGE-CLKCLGNTDGAHCERCADGFYG 891
Query: 1050 DPTNGGQCTACTC---SGHANICHLHTGKCFCTTKGIKGDQCQLC 1091
D C AC C H+ +CHL TG C C + G QC C
Sbjct: 892 DAVTAKNCRACECHVKGSHSAVCHLETGLCDC-KPNVTGQQCDQC 935
Score = 59.7 bits (143), Expect = 2e-08
Identities = 44/144 (30%), Positives = 52/144 (36%), Gaps = 37/144 (25%)
Query: 969 RGHCIEGSSRGPMKLIGMHHSEMVLDTNLCPKEKNYEWSFIQCPACQCNGHS-TCI-NNN 1026
RG GS RGP L+ C C CN HS TC N
Sbjct: 1382 RGKLPAGSDRGPRPLVA------------------------PCVPCSCNNHSDTCDPNTG 1417
Query: 1027 VCEQCKNLTTGKQCQDCMPGYYGDPT-NGGQCTACTC-----SGHANICHL---HTGKCF 1077
C C + T G C C GYYG T + C C C + + C L H +C
Sbjct: 1418 KCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCD 1477
Query: 1078 CTTKGIKGDQCQLCDSENRYVGNP 1101
G +G C+ C S Y GNP
Sbjct: 1478 ACLLGYEGKHCERCSSS--YYGNP 1499
Score = 59.7 bits (143), Expect = 2e-08
Identities = 49/162 (30%), Positives = 68/162 (41%), Gaps = 24/162 (14%)
Query: 936 ATCSPQNCSGLR-TCGQCLEQPGCGWC-NDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVL 993
A C P +C+ TC P G C N NT HC +S K+ G
Sbjct: 1398 APCVPCSCNNHSDTC-----DPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGS-----AS 1447
Query: 994 DTNLCPKEKNYEWSFIQCPACQCNGHSTCINNNVCEQCKNLTTGKQCQDCMPGYYGDP-T 1052
D LC + SF P C G ++ C+ C GK C+ C YYG+P T
Sbjct: 1448 DCALCACPHSPPASF--SPTCVLEGD----HDFRCDACLLGYEGKHCERCSSSYYGNPQT 1501
Query: 1053 NGGQCTACTCSGHANI---CHLHTGKCFCT--TKGIKGDQCQ 1089
GG C C C+ H ++ C +G+C C G++ D+C+
Sbjct: 1502 PGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECE 1543
Score = 56.2 bits (134), Expect = 2e-07
Identities = 65/259 (25%), Positives = 96/259 (37%), Gaps = 65/259 (25%)
Query: 863 CTSMANGLVCEK--------PVVSPNQNARPCKKPCSLRTS-----CSNCTSNGMECMWC 909
C G+ CE+ P + +PC P ++ ++ C + + C WC
Sbjct: 760 CAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWC 819
Query: 910 SS------TKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGL---RTCGQCLEQPG-CG 959
+ +RC D + P C+ P +CSG G C G C
Sbjct: 820 APGYSGAWCERCADGYYGNPTVPGESCV--------PCDCSGNVDPSEAGHCDSVTGECL 871
Query: 960 WCNDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNLCPKEKNYEWSFIQCPACQCN-- 1017
C NT HC E + G + + V N C AC+C+
Sbjct: 872 KCL--GNTDGAHC-ERCADG-------FYGDAVTAKN--------------CRACECHVK 907
Query: 1018 -GHSTC--INNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCSGHANICHLHT- 1073
HS + +C+ CK TG+QC C+ GYYG + G C C CS ++ T
Sbjct: 908 GSHSAVCHLETGLCD-CKPNVTGQQCDQCLHGYYGLDSGHG-CRPCNCSVAGSVSDGCTD 965
Query: 1074 -GKCFCTTKGIKGDQCQLC 1091
G+C C G+ G +C C
Sbjct: 966 EGQCHC-VPGVAGKRCDRC 983
Score = 55.1 bits (131), Expect = 5e-07
Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 10/73 (13%)
Query: 1031 CKNLTTGKQCQDCMPGYYGDPTNGGQ----------CTACTCSGHANICHLHTGKCFCTT 1080
C T G CQDC PGY+ G C C+C+ H++ C +TGKC
Sbjct: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLNCG 1423
Query: 1081 KGIKGDQCQLCDS 1093
GD C +C S
Sbjct: 1424 DNTAGDHCDVCTS 1436
Score = 52.4 bits (124), Expect = 3e-06
Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 5/78 (6%)
Query: 1030 QCKNLTTGKQCQDCMPGYY--GDPTNGGQCTACTCSGHANICHLHTGKCFCTTKGIKGDQ 1087
+C TG C+ C+ GYY GG C C C GHA C++H G C G
Sbjct: 710 ECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVH-GVCIACAHNTTGVH 768
Query: 1088 CQLCDSENRYVGNPLRGT 1105
C+ C + G P RGT
Sbjct: 769 CEQC--LPGFYGEPSRGT 784
Score = 47.0 bits (110), Expect = 1e-04
Identities = 70/302 (23%), Positives = 100/302 (33%), Gaps = 75/302 (24%)
Query: 840 EPNDSGFCAYLERAAVAGLKANPCTSMANGLVCEK--------PVVSPNQNARPC----- 886
+P+++G C +V G + C +G CE+ V + N A C
Sbjct: 856 DPSEAGHCD-----SVTG-ECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGS 909
Query: 887 -KKPCSLRTSCSNCTSN--GMECMWC-------SSTKRCVDSNAYIISFPYGQCLEWQTA 936
C L T +C N G +C C S C N + C +
Sbjct: 910 HSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQC 969
Query: 937 TCSPQNCSGLRTCGQCL------EQPGCGWCNDPSNTGRGHCIEGSSRGPMKLIGMHHSE 990
C P +G R C +C + C C+ P G P G+
Sbjct: 970 HCVP-GVAGKR-CDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVK--- 1024
Query: 991 MVLDTNLCPKEKNYEWSF---IQCPACQCN----GHSTC-INNNVCEQCKNLTTGKQCQD 1042
C + ++ W + + C AC C+ H C + C QCK+ G+ C
Sbjct: 1025 -------CEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHC-QCKSKFGGRACDQ 1076
Query: 1043 CMPGYYGDPTNGGQCTACTC-----SGHANICHLHTGKCFCT--------TKGIKGDQCQ 1089
C GY P C C C SG A C+L G C C + + G QC
Sbjct: 1077 CSLGYRDFP----DCVPCDCDLRGTSGDA--CNLEQGLCGCVEETGACPCKENVFGPQCN 1130
Query: 1090 LC 1091
C
Sbjct: 1131 EC 1132
Score = 45.8 bits (107), Expect = 3e-04
Identities = 62/264 (23%), Positives = 91/264 (34%), Gaps = 62/264 (23%)
Query: 853 AAVAGLKANPCTSMAN--GLVCEKPV-----VSPNQNARPCKKPCSLRTSCSN-CTSNGM 904
+AV L+ C N G C++ + + RPC CS+ S S+ CT G
Sbjct: 911 SAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCN--CSVAGSVSDGCTDEGQ 968
Query: 905 -ECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLR-TCGQCLEQPGCGWCN 962
C+ + KRC D A+ +Q +C+P +C + TC P G C
Sbjct: 969 CHCVPGVAGKRC-DRCAHGF-------YAYQDGSCTPCDCPHTQNTC-----DPETGECV 1015
Query: 963 DPSNTGRGHCIE------------GSSRGPMKLIGMHHSEMVLDTNLCPKEKNYEW---- 1006
P +T C E G L+G H + T C + +
Sbjct: 1016 CPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACD 1075
Query: 1007 -------SFIQCPACQCNGHST-------------CINNNVCEQCKNLTTGKQCQDCMPG 1046
F C C C+ T C+ CK G QC +C G
Sbjct: 1076 QCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREG 1135
Query: 1047 YYG-DPTNGGQCTACTCSGHANIC 1069
+ N C+ C CSG +++C
Sbjct: 1136 TFALRADNPLGCSPCFCSGLSHLC 1159
Score = 44.7 bits (104), Expect = 6e-04
Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 11/68 (16%)
Query: 1014 CQCNGH-STCINNNVCE----QCKNLTTGKQCQDCMPGYYGDP------TNGGQCTACTC 1062
C C GH S+C + + QC++ T G+ C C PGY+ P ++G C AC C
Sbjct: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329
Query: 1063 SGHANICH 1070
A C+
Sbjct: 330 HNKAKDCY 337
Score = 38.9 bits (89), Expect = 0.034
Identities = 44/189 (23%), Positives = 65/189 (34%), Gaps = 38/189 (20%)
Query: 923 ISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGRGHCIEGSSRGPMK 982
I + + W T Q TCG+ + G+ P G SS +
Sbjct: 271 ICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTV-----SSGNTCE 325
Query: 983 LIGMHHS--EMVLDTNLCPKEKNYEWSFIQCPACQCNGHSTCINNNVCEQCKNLTTGKQC 1040
H+ + D ++ ++K+ A Q G CIN C T G C
Sbjct: 326 ACNCHNKAKDCYYDESVAKQKKSLN------TAGQFRGGGVCIN------CLQNTMGINC 373
Query: 1041 QDCMPGYYG----DPTNGGQCTACTC---SGHANIC-------HLHTGK----CFCTTKG 1082
+ C+ GYY P C C C +++C LH GK C C +G
Sbjct: 374 ETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPC-KEG 432
Query: 1083 IKGDQCQLC 1091
G++C C
Sbjct: 433 YTGEKCDRC 441
Score = 38.9 bits (89), Expect = 0.034
Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 5/63 (7%)
Query: 1011 CPACQCNGHSTCINNNVCEQ---CKNLTTGKQCQDCMPGYYG-DPTNGGQCTACTCSGHA 1066
C +C CN + ++ C CK GK C C PG+Y N C+ C C G +
Sbjct: 451 CVSCGCNPVGSA-SDEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVS 509
Query: 1067 NIC 1069
++C
Sbjct: 510 DVC 512
Score = 36.6 bits (83), Expect = 0.17
Identities = 28/100 (28%), Positives = 38/100 (38%), Gaps = 27/100 (27%)
Query: 1011 CPACQCNG----HSTCINNNVCEQ-----------CKNLTTGKQCQDCMPGYYGDPTNGG 1055
C C C+ S CI +++ CK TG++C C GY PT
Sbjct: 394 CRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPT--- 450
Query: 1056 QCTACTC----SGHANICHLHTGKCFCTTKGIKGDQCQLC 1091
C +C C S C TG C C + ++G C C
Sbjct: 451 -CVSCGCNPVGSASDEPC---TGPCVC-KENVEGKACDRC 485
>gi|50659100 regeneration associated muscle protease isoform b [Homo
sapiens]
Length = 720
Score = 72.4 bits (176), Expect = 3e-12
Identities = 53/194 (27%), Positives = 80/194 (41%), Gaps = 23/194 (11%)
Query: 81 CDPGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAVLRLRFNHFAT 140
C GW G C C + + L P+N C W I P V++LRF +
Sbjct: 116 CRAGWYGGDCMRCGQVLRAPKGQILLESYPLN----AHCEWTIHAKPGFVIQLRFVMLSL 171
Query: 141 E----CSWDHMYVYDGDSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAA 196
E C +D++ V DGD+ G I+ + GNE + + + F SD +
Sbjct: 172 EFDYMCQYDYVEVRDGDN--------RDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGS 223
Query: 197 YNLTGFNIFY-SINSCPNN-CSGHGKCTTSVSVPSQVYCECDKYWKGEACDIPYCKANC- 253
N GF+ Y I +C ++ C G C + C C + G+ C+ + NC
Sbjct: 224 KNFDGFHAIYEEITACSSSPCFHDGTCV--LDKAGSYKCACLAGYTGQRCENLLEERNCS 281
Query: 254 --GSPDHGYCDLTG 265
G P +GY +TG
Sbjct: 282 DPGGPVNGYQKITG 295
Score = 34.7 bits (78), Expect = 0.65
Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 8/77 (10%)
Query: 52 ALYAQVS--QSKPCERTGSCFSGRCVNSTCLCDPGWVGDQCQHCQGRFKLTEPSGYLTDG 109
A+Y +++ S PC G+C + + C C G+ G +C++ ++P G
Sbjct: 231 AIYEEITACSSSPCFHDGTCVLDKAGSYKCACLAGYTGQRCENLLEERNCSDPG-----G 285
Query: 110 PIN-YKYKTKCTWLIEG 125
P+N Y+ T LI G
Sbjct: 286 PVNGYQKITGGPGLING 302
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 71.2 bits (173), Expect = 6e-12
Identities = 77/274 (28%), Positives = 108/274 (39%), Gaps = 49/274 (17%)
Query: 862 PCTSMANGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSN--GMECMWCSSTKRCVDSN 919
PC +G V +P+ CKK C C N G++ C + C +
Sbjct: 746 PCQCNLHGSV--NKFCNPHSGQCECKKEAK-GLQCDTCRENFYGLDVTNCKACD-CDTAG 801
Query: 920 AY---IISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPG---------CGWCN-DPSN 966
+ + + GQC+ C P N G R C +CLE C CN D +
Sbjct: 802 SLPGTVCNAKTGQCI------CKP-NVEG-RQCNKCLEGNFYLRQNNSFLCLPCNCDKTG 853
Query: 967 TGRGHCIEGSSRG--PMKLIGMHHSEMVLDTNLC-PKEKNYEW-SFIQCPACQCNGHSTC 1022
T G + S G P KL L N C P N +F C C+C+ T
Sbjct: 854 TINGSLLCNKSTGQCPCKL-----GVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGT- 907
Query: 1023 INNNVCEQ------CKNLTTGKQCQDCMPGYYGDPTNGGQCTACTC--SGHAN-ICHLHT 1073
+ +C+ C G++C C PG+Y P N C C+C +G N IC+ T
Sbjct: 908 LPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLT 967
Query: 1074 GKCFCTTKGIKGDQCQLCDSENRYVG-NPLRGTC 1106
G+C C I G +C C ++ Y G +P G C
Sbjct: 968 GQCVCQDASIAGQRCDQC--KDHYFGFDPQTGRC 999
Score = 62.8 bits (151), Expect = 2e-09
Identities = 79/322 (24%), Positives = 111/322 (34%), Gaps = 91/322 (28%)
Query: 847 CAYLERAAVAGLKANPCTSMANGLVCEKPVVSPNQ----NARPCK-----KPCSLRTS-- 895
C + + GL + C + N +KP +Q N +PC+ K C S
Sbjct: 536 CLCSQESFTEGLHCDRCLPLYN----DKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVD 591
Query: 896 -------------CSNCTSN--GMECMWC------------SSTKRCVDSNAYIISFPYG 928
C +C N G C C S+ C + + G
Sbjct: 592 PFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNG 651
Query: 929 QCLEWQTA-TCSPQNCSGLRTCGQC---------LEQPGCGWCN-DPSNTGRG----HCI 973
L Q C+ + R C QC L+ GC CN + S T G H
Sbjct: 652 SILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQN 711
Query: 974 EGSSRGPMKLIGMHHSEMVLDTNLCPKEKNYEWSFIQ------CPACQCNGHSTCINNNV 1027
G + +IG+ N+ + F++ C CQCN H + N
Sbjct: 712 SGQCKCKANVIGLRCDHC-----------NFGFKFLRSFNDVGCEPCQCNLHGSV--NKF 758
Query: 1028 CE------QCKNLTTGKQCQDCMPGYYG-DPTNGGQCTACTC----SGHANICHLHTGKC 1076
C +CK G QC C +YG D TN C AC C S +C+ TG+C
Sbjct: 759 CNPHSGQCECKKEAKGLQCDTCRENFYGLDVTN---CKACDCDTAGSLPGTVCNAKTGQC 815
Query: 1077 FCTTKGIKGDQCQLCDSENRYV 1098
C ++G QC C N Y+
Sbjct: 816 IC-KPNVEGRQCNKCLEGNFYL 836
Score = 55.8 bits (133), Expect = 3e-07
Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 13/91 (14%)
Query: 1011 CPACQCNGHSTCINNNVCEQ------CKNLT-TGKQCQDCMPGYYGDPTNGGQCTACTC- 1062
C C C H+T N++C C++ + G++C C Y+G G+C C C
Sbjct: 948 CLPCSC--HTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCH 1005
Query: 1063 -SGHAN-ICHLHTGKCFCTTKGIKGDQCQLC 1091
SG N CHL TG+CFC + + G +C C
Sbjct: 1006 LSGALNETCHLVTGQCFC-KQFVTGSKCDAC 1035
Score = 43.5 bits (101), Expect = 0.001
Identities = 27/103 (26%), Positives = 38/103 (36%), Gaps = 25/103 (24%)
Query: 1014 CQCNGHS-TCINNNVCEQC----KNLTTGKQCQDCMPGYYGDPTNGGQ------CTACTC 1062
CQC+GH+ C + +C ++ T G C C+P Y P G C C C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577
Query: 1063 SGHANICHLHT--------------GKCFCTTKGIKGDQCQLC 1091
+ H+ CH + G C G C+LC
Sbjct: 578 NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELC 620
Score = 32.7 bits (73), Expect = 2.5
Identities = 29/99 (29%), Positives = 38/99 (38%), Gaps = 21/99 (21%)
Query: 201 GFNIFYSINSC---PNNCSGHGKCTTSVSVPSQVYCECDKYWKGEAC----------DIP 247
GF S N P C+ HG + P CEC K KG C D+
Sbjct: 732 GFKFLRSFNDVGCEPCQCNLHGSVNKFCN-PHSGQCECKKEAKGLQCDTCRENFYGLDVT 790
Query: 248 YCKA----NCGSPDHGYCDL-TGEKLCVCNDSWQGPDCS 281
CKA GS C+ TG+ C+C + +G C+
Sbjct: 791 NCKACDCDTAGSLPGTVCNAKTGQ--CICKPNVEGRQCN 827
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 71.2 bits (173), Expect = 6e-12
Identities = 77/274 (28%), Positives = 108/274 (39%), Gaps = 49/274 (17%)
Query: 862 PCTSMANGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSN--GMECMWCSSTKRCVDSN 919
PC +G V +P+ CKK C C N G++ C + C +
Sbjct: 746 PCQCNLHGSV--NKFCNPHSGQCECKKEAK-GLQCDTCRENFYGLDVTNCKACD-CDTAG 801
Query: 920 AY---IISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPG---------CGWCN-DPSN 966
+ + + GQC+ C P N G R C +CLE C CN D +
Sbjct: 802 SLPGTVCNAKTGQCI------CKP-NVEG-RQCNKCLEGNFYLRQNNSFLCLPCNCDKTG 853
Query: 967 TGRGHCIEGSSRG--PMKLIGMHHSEMVLDTNLC-PKEKNYEW-SFIQCPACQCNGHSTC 1022
T G + S G P KL L N C P N +F C C+C+ T
Sbjct: 854 TINGSLLCNKSTGQCPCKL-----GVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGT- 907
Query: 1023 INNNVCEQ------CKNLTTGKQCQDCMPGYYGDPTNGGQCTACTC--SGHAN-ICHLHT 1073
+ +C+ C G++C C PG+Y P N C C+C +G N IC+ T
Sbjct: 908 LPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLT 967
Query: 1074 GKCFCTTKGIKGDQCQLCDSENRYVG-NPLRGTC 1106
G+C C I G +C C ++ Y G +P G C
Sbjct: 968 GQCVCQDASIAGQRCDQC--KDHYFGFDPQTGRC 999
Score = 62.8 bits (151), Expect = 2e-09
Identities = 79/322 (24%), Positives = 111/322 (34%), Gaps = 91/322 (28%)
Query: 847 CAYLERAAVAGLKANPCTSMANGLVCEKPVVSPNQ----NARPCK-----KPCSLRTS-- 895
C + + GL + C + N +KP +Q N +PC+ K C S
Sbjct: 536 CLCSQESFTEGLHCDRCLPLYN----DKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVD 591
Query: 896 -------------CSNCTSN--GMECMWC------------SSTKRCVDSNAYIISFPYG 928
C +C N G C C S+ C + + G
Sbjct: 592 PFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNG 651
Query: 929 QCLEWQTA-TCSPQNCSGLRTCGQC---------LEQPGCGWCN-DPSNTGRG----HCI 973
L Q C+ + R C QC L+ GC CN + S T G H
Sbjct: 652 SILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQN 711
Query: 974 EGSSRGPMKLIGMHHSEMVLDTNLCPKEKNYEWSFIQ------CPACQCNGHSTCINNNV 1027
G + +IG+ N+ + F++ C CQCN H + N
Sbjct: 712 SGQCKCKANVIGLRCDHC-----------NFGFKFLRSFNDVGCEPCQCNLHGSV--NKF 758
Query: 1028 CE------QCKNLTTGKQCQDCMPGYYG-DPTNGGQCTACTC----SGHANICHLHTGKC 1076
C +CK G QC C +YG D TN C AC C S +C+ TG+C
Sbjct: 759 CNPHSGQCECKKEAKGLQCDTCRENFYGLDVTN---CKACDCDTAGSLPGTVCNAKTGQC 815
Query: 1077 FCTTKGIKGDQCQLCDSENRYV 1098
C ++G QC C N Y+
Sbjct: 816 IC-KPNVEGRQCNKCLEGNFYL 836
Score = 55.8 bits (133), Expect = 3e-07
Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 13/91 (14%)
Query: 1011 CPACQCNGHSTCINNNVCEQ------CKNLT-TGKQCQDCMPGYYGDPTNGGQCTACTC- 1062
C C C H+T N++C C++ + G++C C Y+G G+C C C
Sbjct: 948 CLPCSC--HTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCH 1005
Query: 1063 -SGHAN-ICHLHTGKCFCTTKGIKGDQCQLC 1091
SG N CHL TG+CFC + + G +C C
Sbjct: 1006 LSGALNETCHLVTGQCFC-KQFVTGSKCDAC 1035
Score = 43.5 bits (101), Expect = 0.001
Identities = 27/103 (26%), Positives = 38/103 (36%), Gaps = 25/103 (24%)
Query: 1014 CQCNGHS-TCINNNVCEQC----KNLTTGKQCQDCMPGYYGDPTNGGQ------CTACTC 1062
CQC+GH+ C + +C ++ T G C C+P Y P G C C C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577
Query: 1063 SGHANICHLHT--------------GKCFCTTKGIKGDQCQLC 1091
+ H+ CH + G C G C+LC
Sbjct: 578 NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELC 620
Score = 32.7 bits (73), Expect = 2.5
Identities = 29/99 (29%), Positives = 38/99 (38%), Gaps = 21/99 (21%)
Query: 201 GFNIFYSINSC---PNNCSGHGKCTTSVSVPSQVYCECDKYWKGEAC----------DIP 247
GF S N P C+ HG + P CEC K KG C D+
Sbjct: 732 GFKFLRSFNDVGCEPCQCNLHGSVNKFCN-PHSGQCECKKEAKGLQCDTCRENFYGLDVT 790
Query: 248 YCKA----NCGSPDHGYCDL-TGEKLCVCNDSWQGPDCS 281
CKA GS C+ TG+ C+C + +G C+
Sbjct: 791 NCKACDCDTAGSLPGTVCNAKTGQ--CICKPNVEGRQCN 827
>gi|22547221 tolloid-like 1 [Homo sapiens]
Length = 1013
Score = 70.1 bits (170), Expect = 1e-11
Identities = 53/199 (26%), Positives = 85/199 (42%), Gaps = 31/199 (15%)
Query: 58 SQSKPCERTGSCFSGRCVNST----CLCDPGWV----GDQCQHCQGRFKLTEPSGYLT-- 107
S C + CVN+ C C G+V C+ + K+ PSG +T
Sbjct: 729 SDKDECSKDNGGCQHECVNTMGSYMCQCRNGFVLHDNKHDCKEAECEQKIHSPSGLITSP 788
Query: 108 DGPINYKYKTKCTWLIEGYPNAVLRLRFNHFATE----CSWDHMYVYDGDSIYAPLIAVL 163
+ P Y + +CTW I P ++L F+ F E C++DH+ V+DG++ +P++ L
Sbjct: 789 NWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRL 848
Query: 164 SGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYS--------INSCPNNC 215
G +P+ +V T + F SDA+ GF +S S P +
Sbjct: 849 CGNKIPD--------PLVATGNKMFVRFVSDASVQRKGFQATHSTECGGRLKAESKPRDL 900
Query: 216 SGHGKCTTSVSVPSQVYCE 234
H + + + P QV CE
Sbjct: 901 YSHAQFGDN-NYPGQVDCE 918
Score = 49.3 bits (116), Expect = 3e-05
Identities = 44/170 (25%), Positives = 69/170 (40%), Gaps = 20/170 (11%)
Query: 93 CQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAVLRLRFNHFATE----CSWDHMY 148
C G + E + P +Y+ +C W I + + L F F E C++D++
Sbjct: 462 CGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLE 521
Query: 149 VYDGDSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGF--NIFY 206
V DG S +PLI G PE ++ +TS + F SD N GF N F
Sbjct: 522 VRDGTSENSPLIGRFCGYDKPE--------DIRSTSNTLWMKFVSDGTVNKAGFAANFFK 573
Query: 207 SINSC--PNNCSGHGKCTTSVSVPSQVYCECDKYWKGEACDIPYCKANCG 254
+ C P+ +C ++ C C+ ++ D C+A CG
Sbjct: 574 EEDECAKPDRGGCEQRCLNTL---GSYQCACEPGYE-LGPDRRSCEAACG 619
Score = 47.0 bits (110), Expect = 1e-04
Identities = 40/153 (26%), Positives = 58/153 (37%), Gaps = 16/153 (10%)
Query: 62 PCERTGSCFSGRCVNSTCLCDPGWVGDQCQHCQGRFKLTEPSGYLTD----GPINYKYKT 117
P TG+ R V+ + G+ C GR K L G NY +
Sbjct: 856 PLVATGNKMFVRFVSDASVQRKGFQATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQV 915
Query: 118 KCTWLIEGYPNAVLRLRFNHFATE----CSWDHMYVYDGDSIYAPLIAVLSGLIVPEIRG 173
C WL+ + L L F F E C +D++ ++DG A + G PE
Sbjct: 916 DCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGSGPPE--- 972
Query: 174 NETVPEVVTTSGYALLHFFSDAAYNLTGFNIFY 206
E+ + L+HF +D N GF+I Y
Sbjct: 973 -----EIYSIGDSVLIHFHTDDTINKKGFHIRY 1000
Score = 42.0 bits (97), Expect = 0.004
Identities = 44/184 (23%), Positives = 74/184 (40%), Gaps = 26/184 (14%)
Query: 67 GSCFSGRCVNST----CLCDPGW-VGDQCQHCQGRFK--LTEPSGYLTDG--PINYKYKT 117
G C RC+N+ C C+PG+ +G + C+ LT+ +G +T P Y
Sbjct: 584 GGC-EQRCLNTLGSYQCACEPGYELGPDRRSCEAACGGLLTKLNGTITTPGWPKEYPPNK 642
Query: 118 KCTWLIEGYPNAVLRLRFNHFATE----CSWDHMYVYDGDSIYAPLIAVLSGLIVPEIRG 173
C W + + ++F F E C +D++ ++ G S + L G VPE+
Sbjct: 643 NCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIWSGLSSESKLHGKFCGAEVPEV-- 700
Query: 174 NETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCS-GHGKCT-TSVSVPSQV 231
+ + + F SD + GF + S + CS +G C V+
Sbjct: 701 ------ITSQFNNMRIEFKSDNTVSKKGFKAHFF--SDKDECSKDNGGCQHECVNTMGSY 752
Query: 232 YCEC 235
C+C
Sbjct: 753 MCQC 756
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 68.9 bits (167), Expect = 3e-11
Identities = 38/105 (36%), Positives = 54/105 (51%), Gaps = 11/105 (10%)
Query: 1010 QCPACQCNGHSTCINNN--VCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTC---SG 1064
+C C CNGHS + +C C++ T G+ C+ C GYYG+ + G C AC C +
Sbjct: 1683 RCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVH-GSCRACPCPHTNS 1741
Query: 1065 HANICHLHTGKCFCTTK-GIKGDQCQLCDSENRYVGNPLR--GTC 1106
A C ++ G C+ K G G QC+ C Y GNP + G+C
Sbjct: 1742 FATGCVVNGGDVRCSCKAGYTGTQCERC--APGYFGNPQKFGGSC 1784
Score = 63.5 bits (153), Expect = 1e-09
Identities = 69/258 (26%), Positives = 96/258 (37%), Gaps = 51/258 (19%)
Query: 935 TATCSPQNCSGLRTCGQCLEQPGCGWC-NDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVL 993
T C P NC+G QC Q G G C N NT HC E G ++ V
Sbjct: 1681 TGRCVPCNCNG--HSNQC--QDGSGICVNCQHNTAGEHC-ERCQEG-------YYGNAVH 1728
Query: 994 DTNLCPKEKNYEWSFIQCPACQC---NGHST-CINN--NVCEQCKNLTTGKQCQDCMPGY 1047
+ C AC C N +T C+ N +V CK TG QC+ C PGY
Sbjct: 1729 GS---------------CRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGY 1773
Query: 1048 YGDPTN-GGQCTACTC--SGHANICHLHTGKCFC--TTKGIKGDQCQLCDSENRYVGNPL 1102
+G+P GG C C+C +G CH TG C ++C CDS
Sbjct: 1774 FGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS--------- 1824
Query: 1103 RGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSV 1162
C +LL D L+ ++ A + ++++ N LN ++
Sbjct: 1825 ---CVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAI 1881
Query: 1163 GSTAGTISGEETSIVSKN 1180
+ I G E + N
Sbjct: 1882 SNHGSKIEGLERELTDLN 1899
Score = 61.6 bits (148), Expect = 5e-09
Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 4/78 (5%)
Query: 1031 CKNLTTGKQCQDCMPGYYGDPTN--GGQCTACTCSGHANICHLHTGKCFCTTKGIKGDQC 1088
C G CQ C PGYY D G+C C C+GH+N C +G C G+ C
Sbjct: 1656 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHC 1715
Query: 1089 QLCDSENRYVGNPLRGTC 1106
+ C + Y GN + G+C
Sbjct: 1716 ERC--QEGYYGNAVHGSC 1731
Score = 55.5 bits (132), Expect = 4e-07
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 26/107 (24%)
Query: 1010 QCPACQCNGH-STCI-------------------NNNVCEQCKNLTTGKQCQDCMPGY-- 1047
+C AC C+GH S C VC C++ T G C+ C GY
Sbjct: 352 ECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYR 411
Query: 1048 -YGDPTNGGQ-CTACTCS-GHANICHLHTGKCFCTTKGIKGDQCQLC 1091
YG P + C C+C HA+ C +G+C C GD C+ C
Sbjct: 412 PYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHC-KPNFHGDNCEKC 457
Score = 53.9 bits (128), Expect = 1e-06
Identities = 64/240 (26%), Positives = 84/240 (35%), Gaps = 31/240 (12%)
Query: 844 SGFCAYLERAAVAGLK--ANPCTSMANGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTS 901
S FC R+ VA A PC G P SP PC+ P + C+ C +
Sbjct: 1245 SRFCKNSARSLVAFYHKGALPCECHPTGAT--GPHCSPEGGQCPCQ-PNVIGRQCTRCAT 1301
Query: 902 NGM---ECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLE-QPG 957
C CS +R + GQC T PQ C T G
Sbjct: 1302 GHYGFPRCKPCSCGRRLCEEMT-------GQC-RCPPRTVRPQ-CEVCETHSFSFHPMAG 1352
Query: 958 CGWCNDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNLCPKEKNYEWSFIQCPACQCN 1017
C CN R IE + + G + + C + + + F +C C CN
Sbjct: 1353 CEGCN----CSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVPCNCN 1408
Query: 1018 GHSTCINNNVCEQ------CKNLTTGKQCQDCMPG-YYGDPTNGGQCTACTCSGHANICH 1070
T VC+ CK G +C C G ++ DP N CT+C C G N CH
Sbjct: 1409 RDGT--EPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCH 1466
Score = 47.0 bits (110), Expect = 1e-04
Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 14/104 (13%)
Query: 1007 SFIQCPACQCNGHSTCINNNVCEQ------CKNLTTGKQCQDCMPGYYGDPTNGGQCTAC 1060
+F A C H T C C+ G+QC C G+YG P +C C
Sbjct: 1257 AFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP----RCKPC 1312
Query: 1061 TCSGHANICHLHTGKCFCTTKGIKGDQCQLCDSENRYVGNPLRG 1104
+C +C TG+C C + ++ QC++C++ + + +P+ G
Sbjct: 1313 SCG--RRLCEEMTGQCRCPPRTVR-PQCEVCETHS-FSFHPMAG 1352
Score = 44.3 bits (103), Expect = 8e-04
Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 11/68 (16%)
Query: 1014 CQCNGHSTCINNNVCE-----QCKNLTTGKQCQDCMPGYY------GDPTNGGQCTACTC 1062
C CNGH+ N N E +C++ T G+ C C GY +C AC C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
Query: 1063 SGHANICH 1070
GHA+ C+
Sbjct: 359 HGHASNCY 366
Score = 44.3 bits (103), Expect = 8e-04
Identities = 58/210 (27%), Positives = 83/210 (39%), Gaps = 33/210 (15%)
Query: 914 RCVDSNAYIISFPYGQCLEWQTATCSPQN-CSGLRTCGQCLEQPGC-GWCNDPSNTGR-- 969
RC + SFP Q W +A S Q CS + GQC +PG G D +G
Sbjct: 519 RCDTCRSGFYSFPICQAC-WCSALGSYQMPCSSVT--GQCECRPGVTGQRCDRCLSGAYD 575
Query: 970 -GHCIEGSSRG--PMKLI----GMHHSEMVLDTNLCPKEKNYEWSFIQ-----CPACQCN 1017
HC +GSS P I G ++ ++ C + K W+ + C C+C+
Sbjct: 576 FPHC-QGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCH 634
Query: 1018 GHSTCINNNVCEQ------CKNLTTGKQCQDCMPGYYG-DPTNGGQCTACTC---SGHAN 1067
T C Q CK+ G C C GY+ + +N C C C ++
Sbjct: 635 KAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSS 694
Query: 1068 ICHLHTGKCFCTTKGIKGDQCQLCDSENRY 1097
+C +G C C + + G CQ EN Y
Sbjct: 695 MCSGPSGVCQC-REHVVGKVCQ--RPENNY 721
Score = 40.8 bits (94), Expect = 0.009
Identities = 36/135 (26%), Positives = 47/135 (34%), Gaps = 34/135 (25%)
Query: 1011 CPACQCNGHSTCINNNVCEQ------CKNLTTGKQCQDCMPGYYGDP------------- 1051
C C C+ + CEQ CK G C+ C GYY P
Sbjct: 423 CIPCSCDPEHA----DGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTP 478
Query: 1052 ----TNGGQCTACTCSGHA---NICHLHTGKCFCTTKGIKGDQCQLCDSENRYVGNPLRG 1104
G C C+ IC H G+C C G++G +C C S + P+
Sbjct: 479 SSEDPVAGDIKGCDCNLEGVLPEICDAH-GRCLC-RPGVEGPRCDTCRS--GFYSFPICQ 534
Query: 1105 TCYYSLLIDYQFTFS 1119
C+ S L YQ S
Sbjct: 535 ACWCSALGSYQMPCS 549
Score = 37.4 bits (85), Expect = 0.10
Identities = 62/256 (24%), Positives = 98/256 (38%), Gaps = 51/256 (19%)
Query: 205 FYSINSCPN-NCSGHGKCTTSVSVPS----QVYCECDKYWKGEACD------------IP 247
F+ + C NCS G T ++P C C G CD +P
Sbjct: 1347 FHPMAGCEGCNCSRRG--TIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVP 1404
Query: 248 YCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILP-NVKP----FSPS 302
C N + G CD G C+C ++ +G +C NV S+ + P N+K F
Sbjct: 1405 -CNCNRDGTEPGVCD-PGTGACLCKENVEGTEC--NVCREGSFHLDPANLKGCTSCFCFG 1460
Query: 303 VGRASHKA-VLHGKFMWVIGGY-----------TFNYSSFQMV-----LNYNLESSIWNV 345
V H + KF+ ++G + +FN S MV L + S+ W
Sbjct: 1461 VNNQCHSSHKRRTKFVDMLGWHLETADRVDIPVSFNPGSNSMVADLQELPATIHSASWVA 1520
Query: 346 GTPSRGP-LQRYGHSLALYQENIFMYGGRI---ETNDGNVTDELWVFNIHSQSWSTKTPT 401
T G + YG L ++ + G + + D +T + +I + +T P
Sbjct: 1521 PTSYLGDKVSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQLTGQH--MSIIYEETNTPRPD 1578
Query: 402 VLGHGQQYAVEGHSAH 417
L HG+ + VEG+ H
Sbjct: 1579 RLHHGRVHVVEGNFRH 1594
Score = 34.7 bits (78), Expect = 0.65
Identities = 42/163 (25%), Positives = 55/163 (33%), Gaps = 16/163 (9%)
Query: 896 CSNCTSNGMECMWCSSTKRCVDSNAYIIS-FPYGQC-LEWQTATCSPQNCSGLRTCGQCL 953
C C S + C + D I S Y QC L + TCS C L
Sbjct: 566 CDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCS--RCKLLYWNLDKE 623
Query: 954 EQPGCGWCN---DPSNTGRGHCIEGSSRGPMKL-IGMHHSEMVLDTNLCPKEKNYEWSFI 1009
GC C + +G G C +G K +G + D ++ NY
Sbjct: 624 NPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNY----F 679
Query: 1010 QCPACQCNG----HSTCINNNVCEQCKNLTTGKQCQDCMPGYY 1048
C CQC+ S C + QC+ GK CQ YY
Sbjct: 680 GCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
Score = 31.6 bits (70), Expect = 5.5
Identities = 14/35 (40%), Positives = 17/35 (48%), Gaps = 3/35 (8%)
Query: 62 PCERTGSCFSGRCVNS---TCLCDPGWVGDQCQHC 93
PC T S +G VN C C G+ G QC+ C
Sbjct: 1735 PCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769
>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
Length = 1668
Score = 68.9 bits (167), Expect = 3e-11
Identities = 38/105 (36%), Positives = 54/105 (51%), Gaps = 11/105 (10%)
Query: 1010 QCPACQCNGHSTCINNN--VCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTC---SG 1064
+C C CNGHS + +C C++ T G+ C+ C GYYG+ + G C AC C +
Sbjct: 74 RCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVH-GSCRACPCPHTNS 132
Query: 1065 HANICHLHTGKCFCTTK-GIKGDQCQLCDSENRYVGNPLR--GTC 1106
A C ++ G C+ K G G QC+ C Y GNP + G+C
Sbjct: 133 FATGCVVNGGDVRCSCKAGYTGTQCERC--APGYFGNPQKFGGSC 175
Score = 63.5 bits (153), Expect = 1e-09
Identities = 69/258 (26%), Positives = 96/258 (37%), Gaps = 51/258 (19%)
Query: 935 TATCSPQNCSGLRTCGQCLEQPGCGWC-NDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVL 993
T C P NC+G QC Q G G C N NT HC E G ++ V
Sbjct: 72 TGRCVPCNCNG--HSNQC--QDGSGICVNCQHNTAGEHC-ERCQEG-------YYGNAVH 119
Query: 994 DTNLCPKEKNYEWSFIQCPACQC---NGHST-CINN--NVCEQCKNLTTGKQCQDCMPGY 1047
+ C AC C N +T C+ N +V CK TG QC+ C PGY
Sbjct: 120 GS---------------CRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGY 164
Query: 1048 YGDPTN-GGQCTACTC--SGHANICHLHTGKCFC--TTKGIKGDQCQLCDSENRYVGNPL 1102
+G+P GG C C+C +G CH TG C ++C CDS
Sbjct: 165 FGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS--------- 215
Query: 1103 RGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSV 1162
C +LL D L+ ++ A + ++++ N LN ++
Sbjct: 216 ---CVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAI 272
Query: 1163 GSTAGTISGEETSIVSKN 1180
+ I G E + N
Sbjct: 273 SNHGSKIEGLERELTDLN 290
Score = 55.1 bits (131), Expect = 5e-07
Identities = 25/68 (36%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
Query: 1041 QDCMPGYYGDPTN--GGQCTACTCSGHANICHLHTGKCFCTTKGIKGDQCQLCDSENRYV 1098
Q C PGYY D G+C C C+GH+N C +G C G+ C+ C + Y
Sbjct: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERC--QEGYY 114
Query: 1099 GNPLRGTC 1106
GN + G+C
Sbjct: 115 GNAVHGSC 122
Score = 31.6 bits (70), Expect = 5.5
Identities = 14/35 (40%), Positives = 17/35 (48%), Gaps = 3/35 (8%)
Query: 62 PCERTGSCFSGRCVNS---TCLCDPGWVGDQCQHC 93
PC T S +G VN C C G+ G QC+ C
Sbjct: 126 PCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 160
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 68.9 bits (167), Expect = 3e-11
Identities = 38/105 (36%), Positives = 54/105 (51%), Gaps = 11/105 (10%)
Query: 1010 QCPACQCNGHSTCINNN--VCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTC---SG 1064
+C C CNGHS + +C C++ T G+ C+ C GYYG+ + G C AC C +
Sbjct: 1683 RCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVH-GSCRACPCPHTNS 1741
Query: 1065 HANICHLHTGKCFCTTK-GIKGDQCQLCDSENRYVGNPLR--GTC 1106
A C ++ G C+ K G G QC+ C Y GNP + G+C
Sbjct: 1742 FATGCVVNGGDVRCSCKAGYTGTQCERC--APGYFGNPQKFGGSC 1784
Score = 63.5 bits (153), Expect = 1e-09
Identities = 69/258 (26%), Positives = 96/258 (37%), Gaps = 51/258 (19%)
Query: 935 TATCSPQNCSGLRTCGQCLEQPGCGWC-NDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVL 993
T C P NC+G QC Q G G C N NT HC E G ++ V
Sbjct: 1681 TGRCVPCNCNG--HSNQC--QDGSGICVNCQHNTAGEHC-ERCQEG-------YYGNAVH 1728
Query: 994 DTNLCPKEKNYEWSFIQCPACQC---NGHST-CINN--NVCEQCKNLTTGKQCQDCMPGY 1047
+ C AC C N +T C+ N +V CK TG QC+ C PGY
Sbjct: 1729 GS---------------CRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGY 1773
Query: 1048 YGDPTN-GGQCTACTC--SGHANICHLHTGKCFC--TTKGIKGDQCQLCDSENRYVGNPL 1102
+G+P GG C C+C +G CH TG C ++C CDS
Sbjct: 1774 FGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS--------- 1824
Query: 1103 RGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSV 1162
C +LL D L+ ++ A + ++++ N LN ++
Sbjct: 1825 ---CVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAI 1881
Query: 1163 GSTAGTISGEETSIVSKN 1180
+ I G E + N
Sbjct: 1882 SNHGSKIEGLERELTDLN 1899
Score = 61.6 bits (148), Expect = 5e-09
Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 4/78 (5%)
Query: 1031 CKNLTTGKQCQDCMPGYYGDPTN--GGQCTACTCSGHANICHLHTGKCFCTTKGIKGDQC 1088
C G CQ C PGYY D G+C C C+GH+N C +G C G+ C
Sbjct: 1656 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHC 1715
Query: 1089 QLCDSENRYVGNPLRGTC 1106
+ C + Y GN + G+C
Sbjct: 1716 ERC--QEGYYGNAVHGSC 1731
Score = 55.5 bits (132), Expect = 4e-07
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 26/107 (24%)
Query: 1010 QCPACQCNGH-STCI-------------------NNNVCEQCKNLTTGKQCQDCMPGY-- 1047
+C AC C+GH S C VC C++ T G C+ C GY
Sbjct: 352 ECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYR 411
Query: 1048 -YGDPTNGGQ-CTACTCS-GHANICHLHTGKCFCTTKGIKGDQCQLC 1091
YG P + C C+C HA+ C +G+C C GD C+ C
Sbjct: 412 PYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHC-KPNFHGDNCEKC 457
Score = 53.9 bits (128), Expect = 1e-06
Identities = 64/240 (26%), Positives = 84/240 (35%), Gaps = 31/240 (12%)
Query: 844 SGFCAYLERAAVAGLK--ANPCTSMANGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTS 901
S FC R+ VA A PC G P SP PC+ P + C+ C +
Sbjct: 1245 SRFCKNSARSLVAFYHKGALPCECHPTGAT--GPHCSPEGGQCPCQ-PNVIGRQCTRCAT 1301
Query: 902 NGM---ECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLE-QPG 957
C CS +R + GQC T PQ C T G
Sbjct: 1302 GHYGFPRCKPCSCGRRLCEEMT-------GQC-RCPPRTVRPQ-CEVCETHSFSFHPMAG 1352
Query: 958 CGWCNDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNLCPKEKNYEWSFIQCPACQCN 1017
C CN R IE + + G + + C + + + F +C C CN
Sbjct: 1353 CEGCN----CSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVPCNCN 1408
Query: 1018 GHSTCINNNVCEQ------CKNLTTGKQCQDCMPG-YYGDPTNGGQCTACTCSGHANICH 1070
T VC+ CK G +C C G ++ DP N CT+C C G N CH
Sbjct: 1409 RDGT--EPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCH 1466
Score = 47.0 bits (110), Expect = 1e-04
Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 14/104 (13%)
Query: 1007 SFIQCPACQCNGHSTCINNNVCEQ------CKNLTTGKQCQDCMPGYYGDPTNGGQCTAC 1060
+F A C H T C C+ G+QC C G+YG P +C C
Sbjct: 1257 AFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP----RCKPC 1312
Query: 1061 TCSGHANICHLHTGKCFCTTKGIKGDQCQLCDSENRYVGNPLRG 1104
+C +C TG+C C + ++ QC++C++ + + +P+ G
Sbjct: 1313 SCG--RRLCEEMTGQCRCPPRTVR-PQCEVCETHS-FSFHPMAG 1352
Score = 44.3 bits (103), Expect = 8e-04
Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 11/68 (16%)
Query: 1014 CQCNGHSTCINNNVCE-----QCKNLTTGKQCQDCMPGYY------GDPTNGGQCTACTC 1062
C CNGH+ N N E +C++ T G+ C C GY +C AC C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
Query: 1063 SGHANICH 1070
GHA+ C+
Sbjct: 359 HGHASNCY 366
Score = 44.3 bits (103), Expect = 8e-04
Identities = 58/210 (27%), Positives = 83/210 (39%), Gaps = 33/210 (15%)
Query: 914 RCVDSNAYIISFPYGQCLEWQTATCSPQN-CSGLRTCGQCLEQPGC-GWCNDPSNTGR-- 969
RC + SFP Q W +A S Q CS + GQC +PG G D +G
Sbjct: 519 RCDTCRSGFYSFPICQAC-WCSALGSYQMPCSSVT--GQCECRPGVTGQRCDRCLSGAYD 575
Query: 970 -GHCIEGSSRG--PMKLI----GMHHSEMVLDTNLCPKEKNYEWSFIQ-----CPACQCN 1017
HC +GSS P I G ++ ++ C + K W+ + C C+C+
Sbjct: 576 FPHC-QGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCH 634
Query: 1018 GHSTCINNNVCEQ------CKNLTTGKQCQDCMPGYYG-DPTNGGQCTACTC---SGHAN 1067
T C Q CK+ G C C GY+ + +N C C C ++
Sbjct: 635 KAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSS 694
Query: 1068 ICHLHTGKCFCTTKGIKGDQCQLCDSENRY 1097
+C +G C C + + G CQ EN Y
Sbjct: 695 MCSGPSGVCQC-REHVVGKVCQ--RPENNY 721
Score = 40.8 bits (94), Expect = 0.009
Identities = 36/135 (26%), Positives = 47/135 (34%), Gaps = 34/135 (25%)
Query: 1011 CPACQCNGHSTCINNNVCEQ------CKNLTTGKQCQDCMPGYYGDP------------- 1051
C C C+ + CEQ CK G C+ C GYY P
Sbjct: 423 CIPCSCDPEHA----DGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTP 478
Query: 1052 ----TNGGQCTACTCSGHA---NICHLHTGKCFCTTKGIKGDQCQLCDSENRYVGNPLRG 1104
G C C+ IC H G+C C G++G +C C S + P+
Sbjct: 479 SSEDPVAGDIKGCDCNLEGVLPEICDAH-GRCLC-RPGVEGPRCDTCRS--GFYSFPICQ 534
Query: 1105 TCYYSLLIDYQFTFS 1119
C+ S L YQ S
Sbjct: 535 ACWCSALGSYQMPCS 549
Score = 37.4 bits (85), Expect = 0.10
Identities = 62/256 (24%), Positives = 98/256 (38%), Gaps = 51/256 (19%)
Query: 205 FYSINSCPN-NCSGHGKCTTSVSVPS----QVYCECDKYWKGEACD------------IP 247
F+ + C NCS G T ++P C C G CD +P
Sbjct: 1347 FHPMAGCEGCNCSRRG--TIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVP 1404
Query: 248 YCKANCGSPDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYWILP-NVKP----FSPS 302
C N + G CD G C+C ++ +G +C NV S+ + P N+K F
Sbjct: 1405 -CNCNRDGTEPGVCD-PGTGACLCKENVEGTEC--NVCREGSFHLDPANLKGCTSCFCFG 1460
Query: 303 VGRASHKA-VLHGKFMWVIGGY-----------TFNYSSFQMV-----LNYNLESSIWNV 345
V H + KF+ ++G + +FN S MV L + S+ W
Sbjct: 1461 VNNQCHSSHKRRTKFVDMLGWHLETADRVDIPVSFNPGSNSMVADLQELPATIHSASWVA 1520
Query: 346 GTPSRGP-LQRYGHSLALYQENIFMYGGRI---ETNDGNVTDELWVFNIHSQSWSTKTPT 401
T G + YG L ++ + G + + D +T + +I + +T P
Sbjct: 1521 PTSYLGDKVSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQLTGQH--MSIIYEETNTPRPD 1578
Query: 402 VLGHGQQYAVEGHSAH 417
L HG+ + VEG+ H
Sbjct: 1579 RLHHGRVHVVEGNFRH 1594
Score = 34.7 bits (78), Expect = 0.65
Identities = 42/163 (25%), Positives = 55/163 (33%), Gaps = 16/163 (9%)
Query: 896 CSNCTSNGMECMWCSSTKRCVDSNAYIIS-FPYGQC-LEWQTATCSPQNCSGLRTCGQCL 953
C C S + C + D I S Y QC L + TCS C L
Sbjct: 566 CDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCS--RCKLLYWNLDKE 623
Query: 954 EQPGCGWCN---DPSNTGRGHCIEGSSRGPMKL-IGMHHSEMVLDTNLCPKEKNYEWSFI 1009
GC C + +G G C +G K +G + D ++ NY
Sbjct: 624 NPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNY----F 679
Query: 1010 QCPACQCNG----HSTCINNNVCEQCKNLTTGKQCQDCMPGYY 1048
C CQC+ S C + QC+ GK CQ YY
Sbjct: 680 GCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
Score = 31.6 bits (70), Expect = 5.5
Identities = 14/35 (40%), Positives = 17/35 (48%), Gaps = 3/35 (8%)
Query: 62 PCERTGSCFSGRCVNS---TCLCDPGWVGDQCQHC 93
PC T S +G VN C C G+ G QC+ C
Sbjct: 1735 PCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769
>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
Length = 1724
Score = 68.9 bits (167), Expect = 3e-11
Identities = 38/105 (36%), Positives = 54/105 (51%), Gaps = 11/105 (10%)
Query: 1010 QCPACQCNGHSTCINNN--VCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTC---SG 1064
+C C CNGHS + +C C++ T G+ C+ C GYYG+ + G C AC C +
Sbjct: 74 RCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVH-GSCRACPCPHTNS 132
Query: 1065 HANICHLHTGKCFCTTK-GIKGDQCQLCDSENRYVGNPLR--GTC 1106
A C ++ G C+ K G G QC+ C Y GNP + G+C
Sbjct: 133 FATGCVVNGGDVRCSCKAGYTGTQCERC--APGYFGNPQKFGGSC 175
Score = 63.5 bits (153), Expect = 1e-09
Identities = 69/258 (26%), Positives = 96/258 (37%), Gaps = 51/258 (19%)
Query: 935 TATCSPQNCSGLRTCGQCLEQPGCGWC-NDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVL 993
T C P NC+G QC Q G G C N NT HC E G ++ V
Sbjct: 72 TGRCVPCNCNG--HSNQC--QDGSGICVNCQHNTAGEHC-ERCQEG-------YYGNAVH 119
Query: 994 DTNLCPKEKNYEWSFIQCPACQC---NGHST-CINN--NVCEQCKNLTTGKQCQDCMPGY 1047
+ C AC C N +T C+ N +V CK TG QC+ C PGY
Sbjct: 120 GS---------------CRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGY 164
Query: 1048 YGDPTN-GGQCTACTC--SGHANICHLHTGKCFC--TTKGIKGDQCQLCDSENRYVGNPL 1102
+G+P GG C C+C +G CH TG C ++C CDS
Sbjct: 165 FGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS--------- 215
Query: 1103 RGTCYYSLLIDYQFTFSLLQEDDRHHTAINFIANPEQSNKNLDISINASNNFNLNITWSV 1162
C +LL D L+ ++ A + ++++ N LN ++
Sbjct: 216 ---CVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAI 272
Query: 1163 GSTAGTISGEETSIVSKN 1180
+ I G E + N
Sbjct: 273 SNHGSKIEGLERELTDLN 290
Score = 55.1 bits (131), Expect = 5e-07
Identities = 25/68 (36%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
Query: 1041 QDCMPGYYGDPTN--GGQCTACTCSGHANICHLHTGKCFCTTKGIKGDQCQLCDSENRYV 1098
Q C PGYY D G+C C C+GH+N C +G C G+ C+ C + Y
Sbjct: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERC--QEGYY 114
Query: 1099 GNPLRGTC 1106
GN + G+C
Sbjct: 115 GNAVHGSC 122
Score = 31.6 bits (70), Expect = 5.5
Identities = 14/35 (40%), Positives = 17/35 (48%), Gaps = 3/35 (8%)
Query: 62 PCERTGSCFSGRCVNS---TCLCDPGWVGDQCQHC 93
PC T S +G VN C C G+ G QC+ C
Sbjct: 126 PCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 160
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 68.2 bits (165), Expect = 5e-11
Identities = 54/180 (30%), Positives = 72/180 (40%), Gaps = 39/180 (21%)
Query: 944 SGLRTCGQCLEQPGCGWCNDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNLCPKEKN 1003
SG + C L+ +CN TG+ HC +G + C +
Sbjct: 816 SGCKPCECHLQGSVNAFCNPV--TGQCHCFQG-----------------VYARQCDRCLP 856
Query: 1004 YEWSFIQCPACQCNGHSTCIN--NNVCEQCKNLTTGKQCQDCMPGYYGDPT--NGGQCTA 1059
W F C CQCNGH+ + C C++ T G C+ C+ GYYGDP +G C
Sbjct: 857 GHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRP 916
Query: 1060 CTC-----SGH--ANICHLHTG----KCFCTTKGIKGDQCQLCDSENRYVGNP--LRGTC 1106
C C SG A C+ C C G G +C C S Y GNP + G+C
Sbjct: 917 CPCPDGPDSGRQFARSCYQDPVTLQLACVC-DPGYIGSRCDDCAS--GYFGNPSEVGGSC 973
Score = 56.2 bits (134), Expect = 2e-07
Identities = 55/199 (27%), Positives = 74/199 (37%), Gaps = 47/199 (23%)
Query: 929 QCL--EWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGRGH----CIEGSSRGPMK 982
+CL W +C P C+G C P G C + + GH C+ G P+
Sbjct: 853 RCLPGHWGFPSCQPCQCNG--HADDC--DPVTGECLNCQDYTMGHNCERCLAGYYGDPII 908
Query: 983 LIGMHHSEMVLDTNLCPKEKNYEWSFIQCPACQCNGHS---TCINNNVCEQ----CKNLT 1035
G H CP CP +G +C + V Q C
Sbjct: 909 GSGDH-------CRPCP-----------CPDGPDSGRQFARSCYQDPVTLQLACVCDPGY 950
Query: 1036 TGKQCQDCMPGYYGDPTN-GGQCTACTCSGHANI-------CHLHTGKCFCTTKGIKGDQ 1087
G +C DC GY+G+P+ GG C C C H NI C TG+C +G+
Sbjct: 951 IGSRCDDCASGYFGNPSEVGGSCQPCQC--HNNIDTTDPEACDKETGRCLKCLYHTEGEH 1008
Query: 1088 CQLCDSENRYVGNPLRGTC 1106
CQ C Y G+ L+ C
Sbjct: 1009 CQFC--RFGYYGDALQQDC 1025
Score = 54.7 bits (130), Expect = 6e-07
Identities = 68/267 (25%), Positives = 94/267 (35%), Gaps = 67/267 (25%)
Query: 863 CTSMANGLVCE-----------KPVVSPNQNARPCKKPCSLRTSCSNCTSNGMECMWCSS 911
C GL CE +P N NA CKK NC + + C +
Sbjct: 300 CRHNTKGLNCELCMDFYHDLPWRPAEGRNSNA--CKK--------CNCNEHSISCHF--- 346
Query: 912 TKRCVDSNAYIIS--FPYGQCLEWQTATCSPQNCSGLRTCGQC-----------LEQPG- 957
D Y+ + G C + Q T R C QC + P
Sbjct: 347 -----DMAVYLATGNVSGGVCDDCQHNTMG-------RNCEQCKPFYYQHPERDIRDPNF 394
Query: 958 CGWCN-DPSNT-GRGHCIEGSSRGPMKLIGMHHSEMVLDTNLCP--KEKNYEWSF---IQ 1010
C C DP+ + G C + + G ++ ++ C KE Y+ S
Sbjct: 395 CERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFG 454
Query: 1011 CPACQCNGHSTCINNNVCEQ------CKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCS- 1063
C +C CN T N C+ CK L TG+ C C+P ++G + C C C
Sbjct: 455 CKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDL 514
Query: 1064 GHA--NICHLHTGKCFCTTKGIKGDQC 1088
G A N C +G+C C I G QC
Sbjct: 515 GGALNNSCFAESGQCSCRPHMI-GRQC 540
Score = 54.7 bits (130), Expect = 6e-07
Identities = 32/110 (29%), Positives = 48/110 (43%), Gaps = 30/110 (27%)
Query: 1011 CPACQCNGHS-TC------------INNNVCEQCKNLTTGKQCQDCMPGYYGDP----TN 1053
C C CN HS +C ++ VC+ C++ T G+ C+ C P YY P +
Sbjct: 332 CKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRD 391
Query: 1054 GGQCTACTC----SGHANICHLHT--------GKCFCTTKGIKGDQCQLC 1091
C CTC S + IC +T G+C C ++G+ C +C
Sbjct: 392 PNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKL-NVEGEHCDVC 440
Score = 47.8 bits (112), Expect = 7e-05
Identities = 53/234 (22%), Positives = 72/234 (30%), Gaps = 54/234 (23%)
Query: 885 PCKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNC- 943
P +PC +C EC+ C + + + YG + C P C
Sbjct: 862 PSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGY-YGDPIIGSGDHCRPCPCP 920
Query: 944 ----SGLRTCGQCLEQP---GCGWCNDPSNTGR--GHCIEGSSRGPMKLIGMHHSEMVLD 994
SG + C + P DP G C G P ++ G
Sbjct: 921 DGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGG--------- 971
Query: 995 TNLCPKEKNYEWSFIQCPACQCNGHSTCINNNVCEQ-------CKNLTTGKQCQDCMPGY 1047
C CQC+ + + C++ C T G+ CQ C GY
Sbjct: 972 ---------------SCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGY 1016
Query: 1048 YGDPTNGGQCTACTCS------GHAN----ICHLHTGKCFCTTKGIKGDQCQLC 1091
YGD C C C+ H N C TG+C C I G C C
Sbjct: 1017 YGDALQ-QDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVI-GQNCDRC 1068
Score = 47.0 bits (110), Expect = 1e-04
Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 1013 ACQCNGH----STCINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCSGHAN- 1067
AC+C+ S C N QC+ G+ C C PG +G +G + C G N
Sbjct: 772 ACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNA 831
Query: 1068 ICHLHTGKCFCTTKGIKGDQCQLC 1091
C+ TG+C C +G+ QC C
Sbjct: 832 FCNPVTGQCHC-FQGVYARQCDRC 854
Score = 46.2 bits (108), Expect = 2e-04
Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 10/88 (11%)
Query: 1011 CPACQCNG-HS---TCINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCSG-- 1064
C C CN HS +C QC G+ C +C ++GDP +C AC C
Sbjct: 1081 CDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDP--DVECRACDCDPRG 1138
Query: 1065 -HANICHLHTGKCFCTTKGIKGDQCQLC 1091
C TG+C C +G++G +C C
Sbjct: 1139 IETPQCDQSTGQCVC-VEGVEGPRCDKC 1165
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 67.8 bits (164), Expect = 7e-11
Identities = 53/179 (29%), Positives = 81/179 (45%), Gaps = 32/179 (17%)
Query: 99 LTEPSG-YLTDG-PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIY 156
LT PSG L+ G P YK C W+IE P +++ F+ F TE ++D + V DG +
Sbjct: 756 LTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYS 815
Query: 157 APLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSI-----NSC 211
APLI V G VP+ +++TS Y L F +D +++ GF + Y + C
Sbjct: 816 APLIGVYHGTQVPQF--------LISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHC 867
Query: 212 -----PNNCSGHG-----------KCTTSVSVPSQVYCECDKYWKGEACDIPYCKANCG 254
P N HG C + ++ EC+ ++ +P C+A CG
Sbjct: 868 LDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRA-LPSCEALCG 925
Score = 62.8 bits (151), Expect = 2e-09
Identities = 40/123 (32%), Positives = 61/123 (49%), Gaps = 11/123 (8%)
Query: 92 HCQGRFKLTEPSGYLTDG--PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYV 149
HC LT+ +G + P +Y C+WL+ P+ + L +F +E +D +
Sbjct: 2354 HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEI 2413
Query: 150 YDGDSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYAL-LHFFSDAAYNLTGFNIFYSI 208
+DG S +PL+ LS GN + P +VT+S ++ L + SD AYN GF I YS
Sbjct: 2414 FDGPSGQSPLLKALS--------GNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA 2465
Query: 209 NSC 211
C
Sbjct: 2466 PYC 2468
Score = 57.4 bits (137), Expect = 9e-08
Identities = 38/123 (30%), Positives = 57/123 (46%), Gaps = 15/123 (12%)
Query: 97 FKLTEPSGYLTDG--PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDS 154
F T PSG + P +Y C WLI P + + L FN E +D + + DG +
Sbjct: 580 FNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGAT 639
Query: 155 IYAPLIAVLSGLIVPEIRGNETVPEVVTTSGY-ALLHFFSDAAYNLTGFNIFYSI---NS 210
AP++ SG +P +T+SG+ A L F +D + GFNI ++ N
Sbjct: 640 AEAPVLGTFSG---------NQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNE 690
Query: 211 CPN 213
CP+
Sbjct: 691 CPD 693
Score = 53.9 bits (128), Expect = 1e-06
Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 13/119 (10%)
Query: 99 LTEPSG-YLTDG-PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIY 156
LTE G L+ G P Y C W I A ++++ F TE +WD + V+DG
Sbjct: 1800 LTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNT 1859
Query: 157 APLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFY---SINSCP 212
++ SG VP + + +TS LHF+SD + + GF++ Y ++SCP
Sbjct: 1860 VTMLGSFSGTTVPAL--------LNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCP 1910
Score = 52.4 bits (124), Expect = 3e-06
Identities = 51/196 (26%), Positives = 77/196 (39%), Gaps = 35/196 (17%)
Query: 81 CDPGWVGD-----QCQHCQGRF---------------KLTEPSGYLTDG--PINYKYKTK 118
CDPG+ C + RF LT PSG + P Y +
Sbjct: 1411 CDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKE 1470
Query: 119 CTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVPEIRGNETVP 178
C W + P+ V+ L FN F E +D +++YDG +PLI G +P
Sbjct: 1471 CDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLP--------G 1522
Query: 179 EVVTTSGYALLHFFSDAAYNLTGFNIFYSIN---SC--PNNCSGHGKCTTSVSVPSQVYC 233
+ ++S L F SDA+ + GF I Y+ N SC P + + + + + S V
Sbjct: 1523 RIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTY 1582
Query: 234 ECDKYWKGEACDIPYC 249
C ++ E C
Sbjct: 1583 YCHGGYEVEGTSTLSC 1598
Score = 47.4 bits (111), Expect = 1e-04
Identities = 51/212 (24%), Positives = 81/212 (38%), Gaps = 46/212 (21%)
Query: 110 PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVP 169
P Y++ C W IE + L F F TE D + ++DG V SG+++
Sbjct: 1289 PAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDG--------PVESGVLLK 1340
Query: 170 EIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSIN---SC-----PNNCSGHG-- 219
E+ G ++ +T +L F +D + GF I +S++ SC P N S G
Sbjct: 1341 ELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGIPQNGSRSGDS 1400
Query: 220 ---------KCTTSVSVPSQVYCECDK-----YWKGEACDIPYCKANCGSPDHGYCDLTG 265
+C ++ C K +W+ P C A CG DLTG
Sbjct: 1401 WEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSP---PTCIAPCGG------DLTG 1451
Query: 266 EKLCVCNDSW-----QGPDCSLNVPSTESYWI 292
+ + ++ G +C V + Y I
Sbjct: 1452 PSGVILSPNYPEPYPPGKECDWKVTVSPDYVI 1483
Score = 41.2 bits (95), Expect = 0.007
Identities = 37/128 (28%), Positives = 54/128 (42%), Gaps = 15/128 (11%)
Query: 91 QHCQGRFKLTEPSGYLTDG--PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMY 148
Q+C F+L P+G + P Y CTW I ++L F FA E +D +
Sbjct: 24 QNCT--FQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLS 81
Query: 149 VYDGDSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSI 208
V+DG L L+G +P T+ TT L SD A + GF+ Y +
Sbjct: 82 VFDGPPQPENLRTRLTGFQLP-----ATIVSAATTLS---LRLISDYAVSAQGFHATYEV 133
Query: 209 ---NSCPN 213
++C N
Sbjct: 134 LPSHTCGN 141
Score = 37.0 bits (84), Expect = 0.13
Identities = 41/154 (26%), Positives = 62/154 (40%), Gaps = 23/154 (14%)
Query: 66 TGSCFSGRCVNS--TCLCDPGWVGDQ----CQHCQGRFKLTEPSGYLTDG-PINYKYKTK 118
T SC SG ++ C+P + + C+ G F L+ G P Y
Sbjct: 890 TFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLN 949
Query: 119 CTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVPE-----IRG 173
CTW+IE + F+ F E D++ + + S PL L+G +P + G
Sbjct: 950 CTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQPL-RQLTGSRLPAPISAGLYG 1008
Query: 174 NETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYS 207
N T A + F SD + + GFNI +S
Sbjct: 1009 NFT----------AQVRFISDFSMSYEGFNITFS 1032
Score = 37.0 bits (84), Expect = 0.13
Identities = 35/126 (27%), Positives = 49/126 (38%), Gaps = 18/126 (14%)
Query: 93 CQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDG 152
C G + + Y P Y C WLI +RL + TE S D + ++DG
Sbjct: 2182 CGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDG 2241
Query: 153 DSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIF------Y 206
AP + V + + + V ++S LL F DAA TG IF Y
Sbjct: 2242 PQQTAPRLGVFTRSMAKK--------TVQSSSNQVLLKFHRDAA---TG-GIFAIAFSAY 2289
Query: 207 SINSCP 212
+ CP
Sbjct: 2290 PLTKCP 2295
Score = 36.2 bits (82), Expect = 0.22
Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 8/97 (8%)
Query: 110 PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVP 169
P NY C+W I ++F +F+TE + D++ + +G + ++ SG +P
Sbjct: 1985 PGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSELP 2044
Query: 170 EIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFY 206
+++TS ++F SD + N GF + Y
Sbjct: 2045 S--------SLLSTSHETTVYFHSDHSQNRPGFKLEY 2073
Score = 32.3 bits (72), Expect = 3.2
Identities = 25/101 (24%), Positives = 40/101 (39%), Gaps = 16/101 (15%)
Query: 110 PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVY--DGDSIYAPLIAVLSGLI 167
P Y CTW I + L F F E +D + V +G S++ +G
Sbjct: 219 PSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTEGSSLW------FTGAS 272
Query: 168 VPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSI 208
+P V+++ + LHF SD + GF+ Y +
Sbjct: 273 LPA--------PVISSKNWLRLHFTSDGNHRQRGFSAQYQV 305
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 67.0 bits (162), Expect = 1e-10
Identities = 72/291 (24%), Positives = 105/291 (36%), Gaps = 69/291 (23%)
Query: 821 WGWED---MSPFTNTTLQWLPGEPNDSGFCAYLERAAVAGLKANPCTSMANGLVCEKPVV 877
W W D + P + +L EP D + ++ A G +P +S L C
Sbjct: 1370 WLWLDYVLVVPENVYSFGYLREEPLDKSY-DFISHCAAQGYHISPSSS---SLFCRNAAA 1425
Query: 878 SP----NQNARPCKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLE- 932
S N ARPC C + G C C +A++I +C
Sbjct: 1426 SLSLFYNNGARPC--------GCHEVGATGPTCEPFGGQCPC---HAHVIGRDCSRCATG 1474
Query: 933 -WQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGRGHCIEGSSRGPMKLIGMHHSEM 991
W C P +C G R C + G C P T C+
Sbjct: 1475 YWGFPNCRPCDC-GARLCDELT-----GQCICPPRTIPPDCL------------------ 1510
Query: 992 VLDTNLCPKEKNYEWSFIQCPACQCNGHS-------TCINNNVCEQCKNLTTGKQCQDCM 1044
LC + + C C C+G TC ++ +C+ TG++C C
Sbjct: 1511 -----LCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCS 1565
Query: 1045 PGYYGDPTNGGQCTACTC--SGHA-NICHLHTGKCFC--TTKGIKGDQCQL 1090
PG++G P +C C C +G A +C TG+C+C +G K DQC L
Sbjct: 1566 PGFHGYP----RCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSL 1612
Score = 62.0 bits (149), Expect = 4e-09
Identities = 31/90 (34%), Positives = 41/90 (45%), Gaps = 10/90 (11%)
Query: 1011 CPACQCNGH-------STCIN-NNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTC 1062
C C C+G+ S C C C TTG +C+ C PG+YG+ G CT C C
Sbjct: 1966 CQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDC 2025
Query: 1063 SG-HANICHLHTGKCFCTTKGIKGDQCQLC 1091
+ C H+G C C G+ G +C C
Sbjct: 2026 TPCGTEACDPHSGHCLCKA-GVTGRRCDRC 2054
Score = 60.5 bits (145), Expect = 1e-08
Identities = 67/285 (23%), Positives = 99/285 (34%), Gaps = 68/285 (23%)
Query: 863 CTSMANGLVCEKP----VVSPNQNARPCKK-PCSLRTSCSN----CTSNG--MECMWC-- 909
C G CE+ V S + + PC PC L +N C G +C+ C
Sbjct: 1883 CQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCL-CKP 1941
Query: 910 ----SSTKRCVDS---NAYIISFPYGQCLEWQTATCSPQNCSG--------------LRT 948
+S +RC N ++ ++C P +CSG
Sbjct: 1942 GYAGASCERCAPGFFGNPLVLG-----------SSCQPCDCSGNGDPNLLFSDCDPLTGA 1990
Query: 949 CGQCLEQ---PGCGWCND--------PSNTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNL 997
C CL P C C P N R C + G + +
Sbjct: 1991 CRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRR 2050
Query: 998 CPKEKNYEWSFIQCPACQCNGHSTCINNNVCE------QCKNLTTGKQCQDCMPGYYGDP 1051
C + + + F C C+ + C C+ T G QC++C PGY+G P
Sbjct: 2051 CDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLP 2110
Query: 1052 TNGGQCTACTCSGHANICHLHTGKCFCTTKGIKGDQCQLCDSENR 1096
G C C C G C HTG+C C G+ G++C C +++
Sbjct: 2111 EQG--CRRCQCPG--GRCDPHTGRCNC-PPGLSGERCDTCSQQHQ 2150
Score = 55.8 bits (133), Expect = 3e-07
Identities = 34/126 (26%), Positives = 48/126 (38%), Gaps = 33/126 (26%)
Query: 998 CPKEKNYEW------SFIQCPACQCNGHST-CI-------------------NNNVCEQC 1031
CP W S +C +C C GH+T C VC C
Sbjct: 337 CPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDC 396
Query: 1032 KNLTTGKQCQDCMPGYYGDPT----NGGQCTACTCSGH--ANICHLHTGKCFCTTKGIKG 1085
++ TTG C+ C+PG+Y P + C C C C TG+C+C G
Sbjct: 397 QHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYC-RPNFSG 455
Query: 1086 DQCQLC 1091
++C +C
Sbjct: 456 ERCDVC 461
Score = 54.7 bits (130), Expect = 6e-07
Identities = 35/105 (33%), Positives = 49/105 (46%), Gaps = 16/105 (15%)
Query: 1010 QCPACQCNGHST-CI-NNNVCEQCKNLTTGKQCQDCMPGYYG---DPTNGGQCTACTC-- 1062
+C CQC+GHS C+ + VC C++ T G C+ C G+ DP+ C +C C
Sbjct: 1860 RCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPS--APCVSCPCPL 1917
Query: 1063 ----SGHANICHLHTGKCFCTTK-GIKGDQCQLCDSENRYVGNPL 1102
+ A C L G+ C K G G C+ C + GNPL
Sbjct: 1918 SVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERC--APGFFGNPL 1960
Score = 52.4 bits (124), Expect = 3e-06
Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 13/91 (14%)
Query: 1008 FIQCPACQCNGHST----CINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCS 1063
F C AC C+ C +C +C+ TG CQ+C PG++G P+ C C CS
Sbjct: 626 FPNCQACTCDPRGALDQLCGAGGLC-RCRPGYTGTACQECSPGFHGFPS----CVPCHCS 680
Query: 1064 GHANI---CHLHTGKCFCTTKGIKGDQCQLC 1091
++ C +G+C C + + G +C C
Sbjct: 681 AEGSLHAACDPRSGQCSCRPR-VTGLRCDTC 710
Score = 47.8 bits (112), Expect = 7e-05
Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 2/65 (3%)
Query: 1031 CKNLTTGKQCQDCMPGYYGDPTNG--GQCTACTCSGHANICHLHTGKCFCTTKGIKGDQC 1088
C G CQ+C PG+Y D G+C C C GH++ C +G C +G C
Sbjct: 1833 CPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHC 1892
Query: 1089 QLCDS 1093
+ C +
Sbjct: 1893 ERCQA 1897
Score = 45.1 bits (105), Expect = 5e-04
Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 7/67 (10%)
Query: 1031 CKNLTTGKQCQDCMPGYYG-DPTNGGQCTACTCS-----GHANICHLHTGKCFCTTKGIK 1084
C+ G C C PG++G P+N CT C+C G C TG+CFC +
Sbjct: 746 CRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPH-VC 804
Query: 1085 GDQCQLC 1091
G C C
Sbjct: 805 GQACASC 811
Score = 42.0 bits (97), Expect = 0.004
Identities = 46/171 (26%), Positives = 57/171 (33%), Gaps = 39/171 (22%)
Query: 938 CSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGR--GHCIEG----SSRGPMKLIGMHHSEM 991
C NC T G C + G +C P+ +G C EG S P E
Sbjct: 426 CRRCNCESDFTDGTCEDLTGRCYCR-PNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQ 484
Query: 992 VLDTNLCPKEKNYEWSFIQCPACQCNGHSTCINNNVCEQ--------CKNLTTGKQCQDC 1043
VL Q C C+ T N C + CK G C+ C
Sbjct: 485 VLPAG-------------QIVNCDCSAAGT--QGNACRKDPRVGRCLCKPNFQGTHCELC 529
Query: 1044 MPGYYGDPTNGGQCTACTCSGHA---NICHLHTGKCFCTTKGIKGDQCQLC 1091
PG+YG C C CS + C TG+C C G +G C C
Sbjct: 530 APGFYGP-----GCQPCQCSSPGVADDRCDPDTGQCRCRV-GFEGATCDRC 574
Score = 40.0 bits (92), Expect = 0.015
Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 13/70 (18%)
Query: 1014 CQCNGHS-TCINNNVCEQ------CKNLTTGKQCQDCMPGYYGDP------TNGGQCTAC 1060
C C+GH+ C + + C++ T G C C PG+ P + +C +C
Sbjct: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSC 359
Query: 1061 TCSGHANICH 1070
C GHA C+
Sbjct: 360 NCYGHATDCY 369
Score = 36.2 bits (82), Expect = 0.22
Identities = 25/90 (27%), Positives = 36/90 (40%), Gaps = 17/90 (18%)
Query: 1011 CPACQCNGHSTCINNNVCE------QCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCSG 1064
C CQC+ S + ++ C+ +C+ G C C PGY+ P C C CS
Sbjct: 538 CQPCQCS--SPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL----CQLCGCSP 591
Query: 1065 HANI---CHLHTGKCFCTTKGIKGDQCQLC 1091
+ C G+C C + G C C
Sbjct: 592 AGTLPEGCD-EAGRCLCQPE-FAGPHCDRC 619
Score = 34.7 bits (78), Expect = 0.65
Identities = 21/78 (26%), Positives = 28/78 (35%), Gaps = 10/78 (12%)
Query: 1011 CPACQCNGHSTCINNNVCEQ------CKNLTTGKQCQDCMPGYYG-DPTNGGQCTACTC- 1062
C C C+ T C+ CK G+ C C G++G D + C +C C
Sbjct: 773 CTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCD 832
Query: 1063 --SGHANICHLHTGKCFC 1078
C TG C C
Sbjct: 833 IGGALGQSCEPRTGVCRC 850
Score = 32.0 bits (71), Expect = 4.2
Identities = 26/81 (32%), Positives = 33/81 (40%), Gaps = 16/81 (19%)
Query: 214 NCSGHG--KCTTSVSVPSQVYCECDKYWKGEACDI--------PYCK-ANC--GSPDHGY 260
NCSG G + T C+C G CD P C+ +C G
Sbjct: 1529 NCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGV 1588
Query: 261 CD-LTGEKLCVCNDSWQGPDC 280
CD LTG+ C C ++ QGP C
Sbjct: 1589 CDPLTGQ--CYCKENVQGPKC 1607
Score = 31.6 bits (70), Expect = 5.5
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Query: 65 RTGSCFSGRCVNST--CLCDPGWVGDQCQHCQGRFKLTEPSG 104
R C GRC T C C PG G++C C + ++ P G
Sbjct: 2115 RRCQCPGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGG 2156
Score = 31.2 bits (69), Expect = 7.2
Identities = 32/107 (29%), Positives = 44/107 (41%), Gaps = 19/107 (17%)
Query: 191 FFSDAAYNLTGFNIFYSINSCPNNCSGHGKCTTSVSVPSQVYCECDKYWKGEACD----- 245
F +AA +L+ +FY+ + P C G T P C C + G C
Sbjct: 1419 FCRNAAASLS---LFYNNGARPCGCHEVG-ATGPTCEPFGGQCPCHAHVIGRDCSRCATG 1474
Query: 246 ---IPYCK-ANCGSPDHGYCD-LTGEKLCVCNDSWQGPDCSLNVPST 287
P C+ +CG+ CD LTG+ C+C PDC L P T
Sbjct: 1475 YWGFPNCRPCDCGAR---LCDELTGQ--CICPPRTIPPDCLLCQPQT 1516
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 66.2 bits (160), Expect = 2e-10
Identities = 37/107 (34%), Positives = 47/107 (43%), Gaps = 15/107 (14%)
Query: 1011 CPACQCNGHSTCIN--NNVCEQCKNLTTGKQCQDCMPGYYGDPTNG--GQCTACTCSGH- 1065
C C C+GHS C+ C++ T G +C+ C PGYYGD G C C C G
Sbjct: 1156 CERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDP 1215
Query: 1066 -----ANICHLHTG---KCFCTTKGIKGDQCQLCDSENRYVGNPLRG 1104
A+ C L T C + G G C+ C Y GNP +G
Sbjct: 1216 AAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERC--APGYYGNPSQG 1260
Score = 63.2 bits (152), Expect = 2e-09
Identities = 37/104 (35%), Positives = 47/104 (45%), Gaps = 15/104 (14%)
Query: 1011 CPACQCNGHSTCIN--NNVCEQCKNLTTGKQCQDCMPGYYGDPTNG--GQCTACTC---- 1062
C C+CNGHS + C QC++ G+ C+ C PGYYGD T G C C C
Sbjct: 1560 CELCECNGHSDLCHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTN 1619
Query: 1063 --SGHANICH-LHTG--KCFCTTKGIKGDQCQLCDSENRYVGNP 1101
+ + C L G +C G G C+ C YVGNP
Sbjct: 1620 PENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGP--GYVGNP 1661
Score = 57.8 bits (138), Expect = 7e-08
Identities = 28/71 (39%), Positives = 35/71 (49%), Gaps = 4/71 (5%)
Query: 1037 GKQCQDCMPGYY--GDPTNGGQCTACTCSGHANICHLHTGKCFCTTKGIKGDQCQLCDSE 1094
G CQDC PGY G G C C C+GH+++CH TG C G+ C+LC
Sbjct: 1538 GLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCELC--A 1595
Query: 1095 NRYVGNPLRGT 1105
Y G+ GT
Sbjct: 1596 PGYYGDATAGT 1606
Score = 51.6 bits (122), Expect = 5e-06
Identities = 26/71 (36%), Positives = 34/71 (47%), Gaps = 4/71 (5%)
Query: 1037 GKQCQDCMPGYYGDPTNG--GQCTACTCSGHANICHLHTGKCFCTTKGIKGDQCQLCDSE 1094
G CQDC GY P+ G C C+C GH+ C TG C +G +C+ C +
Sbjct: 1134 GPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQC--Q 1191
Query: 1095 NRYVGNPLRGT 1105
Y G+ RGT
Sbjct: 1192 PGYYGDAQRGT 1202
Score = 45.8 bits (107), Expect = 3e-04
Identities = 27/103 (26%), Positives = 40/103 (38%), Gaps = 23/103 (22%)
Query: 1011 CPACQCNGHS-------TCI----NNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQC-- 1057
C C C G TC + C+ C +G+ C+ C PGYYG+P+ G C
Sbjct: 1206 CQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQR 1265
Query: 1058 -------TACTCSGHANICHL--HTGKCFCTTKGIKGDQCQLC 1091
C C ++ G+C C + ++G C C
Sbjct: 1266 DSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQ-VEGLTCSHC 1307
Score = 41.2 bits (95), Expect = 0.007
Identities = 53/224 (23%), Positives = 77/224 (34%), Gaps = 49/224 (21%)
Query: 891 SLRTSCSNCTSNGM-------ECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNC 943
++ T+ ++ TS+G C S C +A+ P G L TCS NC
Sbjct: 711 AMDTTVTHATSHGRAHSVEECRCPIGYSGLSCESCDAHFTRVPGGPYL----GTCSGCNC 766
Query: 944 SGLRTCGQCLEQPGCGWC-NDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNLCPKEK 1002
+G C P G C N NT C ++ G CP
Sbjct: 767 NG--HASSC--DPVYGHCLNCQHNTEGPQC----NKCKAGFFGDAMKATATSCRPCP--- 815
Query: 1003 NYEWSFIQCPACQCNGH--STCINNN----VCEQCKNLTTGKQCQDCMPGYYGDPTN-GG 1055
CP + TC + C+ C TG++C+ C PGY G+P GG
Sbjct: 816 --------CPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGG 867
Query: 1056 QCTACTCSGHANICHLHTGKCFCTTKGIKGDQCQLCDSENRYVG 1099
+C ++ C +G G + C +N VG
Sbjct: 868 KCRP-----------VNQEIVRCDERGSMGTSGEACRCKNNVVG 900
Score = 40.4 bits (93), Expect = 0.012
Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 1028 CEQCKNLTTGKQCQDCMPGYYGDPT-NGGQCTACTCSGHANICHLHTGKCFCTTKGIKGD 1086
C C+ TG+ C+ C PGY G+P+ GGQC T + +H + G
Sbjct: 1638 CTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPL-VVEVHPARSIVPQGGSHSL 1696
Query: 1087 QCQLCDSENRY 1097
+CQ+ S Y
Sbjct: 1697 RCQVSGSPPHY 1707
Score = 40.0 bits (92), Expect = 0.015
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 1036 TGKQCQDCMPGYYGDPTNG--GQCTACTCSGHANICHLHTGKCFCTTKGIKGDQCQLCDS 1093
+G C+ C + P G C+ C C+GHA+ C G C +G QC C +
Sbjct: 738 SGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGPQCNKCKA 797
Query: 1094 ENRYVGNPLRGT 1105
+ G+ ++ T
Sbjct: 798 --GFFGDAMKAT 807
Score = 38.5 bits (88), Expect = 0.045
Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 5/71 (7%)
Query: 37 LDGNSWLLCYGFLYLALYAQVSQSKPCERTGSCFSGRCVNS-----TCLCDPGWVGDQCQ 91
++G L Y FL Q S PCER C+ + CLC G+ GD C+
Sbjct: 4082 VNGKRLDLTYSFLGSQGIGQCYDSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCE 4141
Query: 92 HCQGRFKLTEP 102
H + +L EP
Sbjct: 4142 HEENPCQLREP 4152
Score = 36.6 bits (83), Expect = 0.17
Identities = 11/36 (30%), Positives = 19/36 (52%)
Query: 59 QSKPCERTGSCFSGRCVNSTCLCDPGWVGDQCQHCQ 94
+ +PC+ G C + C+C G+ G +C+H Q
Sbjct: 3849 RDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQ 3884
Score = 34.7 bits (78), Expect = 0.65
Identities = 44/194 (22%), Positives = 64/194 (32%), Gaps = 39/194 (20%)
Query: 895 SCSNCTSNGM---------ECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNC-- 943
+CS C NG C+ C N F +G ++ +C P C
Sbjct: 760 TCSGCNCNGHASSCDPVYGHCLNCQHNTEGPQCNKCKAGF-FGDAMKATATSCRPCPCPY 818
Query: 944 --SGLRTCGQC-LEQPGCGWCND--PSNTGRG--HCIEGSSRGPMKLIGMHHSEMVLDTN 996
+ R C L+ G C+ P TGR C G P++ G
Sbjct: 819 IDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGG----------- 867
Query: 997 LCPKEKNYEWSFIQCPACQCNGHSTCINNNVCEQCKNLTTGKQCQDCMPG-YYGDPTNGG 1055
K + ++C G S C +CKN G+ C +C G ++ N
Sbjct: 868 ---KCRPVNQEIVRCDERGSMGTS----GEAC-RCKNNVVGRLCNECADGSFHLSTRNPD 919
Query: 1056 QCTACTCSGHANIC 1069
C C C G + C
Sbjct: 920 GCLKCFCMGVSRHC 933
Score = 33.9 bits (76), Expect = 1.1
Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 59 QSKPCERTGSCF-SGRCVNSTCLCDPGWVGDQCQHCQG 95
+ PC+ C G C + CLC PG+ G +CQ G
Sbjct: 4143 EENPCQLREPCLHGGTCQGTRCLCLPGFSGPRCQQGSG 4180
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 66.2 bits (160), Expect = 2e-10
Identities = 66/244 (27%), Positives = 93/244 (38%), Gaps = 55/244 (22%)
Query: 899 CTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTC----GQCLE 954
C G+ S ++ C + + Y L Q C+PQ S C GQCL
Sbjct: 749 CHEEGLVPSKTSPSEACAPLLISLSTLIYNGALPCQ---CNPQG-SLSSECNPHGGQCLC 804
Query: 955 QPG-----CGWCNDPSNTGRG----HCIEGSSRGPMKLIGMHHSEMVLDTN-----LCPK 1000
+PG C C P G G + S G + + S L C +
Sbjct: 805 KPGVVGRRCDLCA-PGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDR 863
Query: 1001 EKNYEWSFIQCPACQCNGHSTCINNNV--CEQCKNLTTGKQCQDCMPGYYGDP--TNGGQ 1056
+ +W F C C CNGH+ N + C C++ T G+ C+ C+ G++GDP GGQ
Sbjct: 864 CQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQ 923
Query: 1057 CTACTC------------SGHAN------ICHLHTG----KCFCTTKGIKGD------QC 1088
C C C S H + +CH G +C G GD +C
Sbjct: 924 CRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRC 983
Query: 1089 QLCD 1092
QLC+
Sbjct: 984 QLCE 987
Score = 63.9 bits (154), Expect = 1e-09
Identities = 61/228 (26%), Positives = 91/228 (39%), Gaps = 31/228 (13%)
Query: 894 TSCS--NCTSNGMECMWCSSTK-RCV-DSNAYIISFPYGQCLEWQTATCSPQNCSGLRTC 949
T C C+ G C T +C+ + A+ + Q +W +C P C+G
Sbjct: 826 TGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNG--HA 883
Query: 950 GQCLEQPG-CGWCNDPSNTGRGHC---IEGSSRGPMKLIGMHHSEMVLDTNLCPKEKNYE 1005
+C G C C D +TG HC I G P G CP+ +
Sbjct: 884 DECNTHTGACLGCRD--HTGGEHCERCIAGFHGDPRLPYGGQCRPCP-----CPEGPGSQ 936
Query: 1006 WSFIQCPACQCNGHSTCINNNVCEQCKNLTTGKQCQDCMPGYYGDPTN-GGQCTACTCSG 1064
F A C H + + C+ TG +C+ C PG++GDP+ GG+C C CSG
Sbjct: 937 RHF----ATSC--HQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSG 990
Query: 1065 H-----ANICHLHTGKCFCTTKGIKGDQCQLCDSENRYVGNPLRGTCY 1107
+ + C HTG+C +G C C + + G R +C+
Sbjct: 991 NIDPMDPDACDPHTGQCLRCLHHTEGPHCAHC--KPGFHGQAARQSCH 1036
Score = 52.0 bits (123), Expect = 4e-06
Identities = 31/110 (28%), Positives = 50/110 (45%), Gaps = 30/110 (27%)
Query: 1011 CPACQCNGHS-TC------------INNNVCEQCKNLTTGKQCQDCMPGYYGDPT----N 1053
C C+C+GH+ +C ++ VC+ C++ T G+ C+ C P +Y DPT +
Sbjct: 344 CRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRD 403
Query: 1054 GGQCTACTC----SGHANICHLH--------TGKCFCTTKGIKGDQCQLC 1091
C +C C S C H +G+C C + + G +CQ C
Sbjct: 404 PAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRC-KEHVVGTRCQQC 452
Score = 50.8 bits (120), Expect = 9e-06
Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 10/88 (11%)
Query: 1011 CPACQCNGHSTCINNNVCEQ------CKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCSG 1064
C CQCN T + C+ CK L TG+ C C+PG++G + C C C
Sbjct: 467 CRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDV 526
Query: 1065 HANI---CHLHTGKCFCTTKGIKGDQCQ 1089
+ C TG+C C + + G +C+
Sbjct: 527 GGALDPQCDEGTGQCHC-RQHMVGRRCE 553
Score = 47.8 bits (112), Expect = 7e-05
Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 13/96 (13%)
Query: 1006 WSFIQCPACQ-CNGHSTCINNNVCEQ------CKNLTTGKQCQDCMPGYYGDPTNGGQCT 1058
W+ CQ C H + C + C+ G+ C +C ++GDP G QC
Sbjct: 1084 WNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDP--GLQCH 1141
Query: 1059 ACTCSGH---ANICHLHTGKCFCTTKGIKGDQCQLC 1091
AC C CH TG C C G+ G +C C
Sbjct: 1142 ACDCDSRGIDTPQCHRFTGHCSC-RPGVSGVRCDQC 1176
Score = 43.9 bits (102), Expect = 0.001
Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 20/100 (20%)
Query: 1010 QCPACQCNGHSTCINNNVCE-------QCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTC 1062
+C C+C+G+ ++ + C+ +C + T G C C PG++G C CTC
Sbjct: 982 RCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAAR-QSCHRCTC 1040
Query: 1063 S---------GHANICHL--HTGKCFCTTKGIKGDQCQLC 1091
+ + CH +G+C C ++G C C
Sbjct: 1041 NLLGTNPQQCPSPDQCHCDPSSGQCPC-LPNVQGPSCDRC 1079
Score = 42.7 bits (99), Expect = 0.002
Identities = 71/307 (23%), Positives = 98/307 (31%), Gaps = 73/307 (23%)
Query: 863 CTSMANGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSNGMECMWCSS------TKRCV 916
C + A GL C++ Q P +PC C ++ C+ C +RC+
Sbjct: 852 CRTGAFGLRCDR--CQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCI 909
Query: 917 DSNAYIISFPYG-QCLEWQ-----------TATCSPQNCSGLRTC-------GQCLEQPG 957
PYG QC +C S C G E
Sbjct: 910 AGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACA 969
Query: 958 CGWCNDPSNTGRGHCIEGSSRG---PMK-----------LIGMHHSEMVLDTNLCPKEKN 1003
G DPS G G C G PM L +HH+E + C +
Sbjct: 970 PGHFGDPSRPG-GRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAH-CKPGFH 1027
Query: 1004 YEWSFIQCPACQCNGHST----CINNNVCE------QCKNLTT--GKQCQDCMPGYYGDP 1051
+ + C C CN T C + + C QC L G C C P ++ +
Sbjct: 1028 GQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFW-NL 1086
Query: 1052 TNGGQCTACTCS---GHANICHLHTGKCFCTTK--------------GIKGDQCQLCDSE 1094
T+G C C C C+ TG+C C G G QC CD +
Sbjct: 1087 TSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCD 1146
Query: 1095 NRYVGNP 1101
+R + P
Sbjct: 1147 SRGIDTP 1153
Score = 38.1 bits (87), Expect = 0.059
Identities = 18/68 (26%), Positives = 31/68 (45%), Gaps = 7/68 (10%)
Query: 1030 QCKNLTTGKQCQDCMPGYYG-DPTNGGQCTACTCSGHANI-----CHLHTGKCFCTTKGI 1083
+CK G +CQ C G++G ++ C C C+ + C ++G C+C + +
Sbjct: 439 RCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYC-KRLV 497
Query: 1084 KGDQCQLC 1091
G C C
Sbjct: 498 TGRGCDRC 505
Score = 37.7 bits (86), Expect = 0.077
Identities = 21/79 (26%), Positives = 28/79 (35%), Gaps = 14/79 (17%)
Query: 1019 HSTCINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQ------CTACTCSGHANICHLH 1072
H CI CK+ T G C+ C Y P + C C C GH + CH
Sbjct: 307 HGACI-------CKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFD 359
Query: 1073 TGKCFCTTKGIKGDQCQLC 1091
+ + + G C C
Sbjct: 360 MA-VYLASGNVSGGVCDGC 377
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 65.5 bits (158), Expect = 3e-10
Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 7/100 (7%)
Query: 1008 FIQCPACQCNGHSTCINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNG--GQCTACTCSGH 1065
+ C C CN H TC N C + T G C+ C+PG+YG+P G C C C G
Sbjct: 701 YASCVPCTCNQHGTCDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQ 760
Query: 1066 ANICHLHTGK---CFCTTKGIKGDQCQLCDSENRYVGNPL 1102
+ + + C G +G +C++CD + + G+PL
Sbjct: 761 SACTTIPESREVVCTHCPPGQRGRRCEVCD--DGFFGDPL 798
Score = 57.4 bits (137), Expect = 9e-08
Identities = 58/227 (25%), Positives = 85/227 (37%), Gaps = 53/227 (23%)
Query: 880 NQNARPCKKPCSLRTSCSNCTSN--GMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTAT 937
N +A C + + +C C N G +C +RC+ P+ Q W T
Sbjct: 274 NGHASECGPDVAGQLAC-RCQHNTTGTDC------ERCL---------PFFQDRPWARGT 317
Query: 938 ------CSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGRGHCIEGSSRGPMKLIGMHHSEM 991
C P NCSG +C + GR H + GP H E
Sbjct: 318 AEAAHECLPCNCSGRSE--ECTFDREL--FRSTGHGGRCHHCRDHTAGP-------HCER 366
Query: 992 VLDTNLCPKEKNYEWS-FIQCPACQCNG----HSTCINNNVCEQCKNLTTGKQCQDCMPG 1046
+E Y W + C C C H C + C CK TG +C C+PG
Sbjct: 367 C-------QENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCA-CKPTVTGWKCDRCLPG 418
Query: 1047 YYGDPTNGGQCTACTC--SGHANICHLHTGKCFCTTKGIKGDQCQLC 1091
++ + G C CTC +G + C +G+C C + ++G+ C C
Sbjct: 419 FHS--LSEGGCRPCTCNPAGSLDTCDPRSGRCPC-KENVEGNLCDRC 462
Score = 57.0 bits (136), Expect = 1e-07
Identities = 63/248 (25%), Positives = 85/248 (34%), Gaps = 49/248 (19%)
Query: 863 CTSMANGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYI 922
C S A G E P P + PC C+ +C T C+ CS +
Sbjct: 684 CESCAPGYKREMPQGGPYASCVPCT--CNQHGTCDPNTGI---CV-CSHHTEGPSCERCL 737
Query: 923 ISFPYGQCLEWQTATCSPQNCSGLRTCGQCLE--QPGCGWCNDPSNTGRGH--CIEGSSR 978
F YG Q C P C G C E + C C P GR C +G
Sbjct: 738 PGF-YGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHC-PPGQRGRRCEVCDDGFFG 795
Query: 979 GPMKLIGMHHSEMVLDTNLCPKEKNYEWSFIQCPACQCNGH--STCINN-----NVCEQC 1031
P+ L G H + C CQC+G+ + N C +C
Sbjct: 796 DPLGLFG--HPQ-------------------PCHQCQCSGNVDPNAVGNCDPLSGHCLRC 834
Query: 1032 KNLTTGKQCQDCMPGYYGD---PTNGGQCTACTCSGHANI-----CHLHTGKCFCTTKGI 1083
+ TTG C+ C G+YG P +C C+C ++ C TG+C C +
Sbjct: 835 LHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPH-V 893
Query: 1084 KGDQCQLC 1091
C C
Sbjct: 894 TARDCSRC 901
Score = 54.7 bits (130), Expect = 6e-07
Identities = 62/254 (24%), Positives = 87/254 (34%), Gaps = 52/254 (20%)
Query: 863 CTSMANGLVCEK--------PVVSPNQNARPCKKPCSLRTSCSNCT-SNGMECMWC---S 910
C+ G CE+ P + +PC PC +++C+ S + C C
Sbjct: 724 CSHHTEGPSCERCLPGFYGNPFAGQADDCQPC--PCPGQSACTTIPESREVVCTHCPPGQ 781
Query: 911 STKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGL---RTCGQCLEQPGCGWC-NDPSN 966
+RC + P G L C CSG G C P G C N
Sbjct: 782 RGRRCEVCDDGFFGDPLG--LFGHPQPCHQCQCSGNVDPNAVGNC--DPLSGHCLRCLHN 837
Query: 967 TGRGHCIEGSSRGPMKLIGMHHSEMVLDTNLCPKEKNYEWSFIQCPACQCNGHSTCINNN 1026
T HC H E + L P+ + +C C C+ +
Sbjct: 838 TTGDHC-------------EHCQEGFYGSALAPRPAD------KCMPCSCHPQGSVSEQM 878
Query: 1027 VCE----QCKNL--TTGKQCQDCMPGYYGDPTNGGQCTACTC---SGHANICHLHTGKCF 1077
C+ QC L T + C C PG++ D G C +C C + CH TG+C
Sbjct: 879 PCDPVTGQCSCLPHVTARDCSRCYPGFF-DLQPGRGCRSCKCHPLGSQEDQCHPKTGQCT 937
Query: 1078 CTTKGIKGDQCQLC 1091
C G+ G C C
Sbjct: 938 C-RPGVTGQACDRC 950
Score = 53.1 bits (126), Expect = 2e-06
Identities = 32/107 (29%), Positives = 46/107 (42%), Gaps = 20/107 (18%)
Query: 1014 CQCNGHSTCINNNVCEQ----CKNLTTGKQCQDCMPGYYGDPTNGG------QCTACTCS 1063
C+CNGH++ +V Q C++ TTG C+ C+P + P G +C C CS
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 1064 GHANICHL---------HTGKCFCTTKGIKGDQCQLCDSENRYVGNP 1101
G + C H G+C G C+ C EN Y +P
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERC-QENFYHWDP 376
Score = 48.9 bits (115), Expect = 3e-05
Identities = 27/77 (35%), Positives = 36/77 (46%), Gaps = 7/77 (9%)
Query: 1031 CKNLTTGKQCQDCMPGYYGDPTNGG---QCTACTCSGHANICHLHTGKCFCTTKGIKGDQ 1087
C TG+ C+ C PGY + GG C CTC+ H C +TG C C + +G
Sbjct: 675 CPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDPNTGICVC-SHHTEGPS 732
Query: 1088 CQLCDSENRYVGNPLRG 1104
C+ C + GNP G
Sbjct: 733 CERC--LPGFYGNPFAG 747
Score = 43.5 bits (101), Expect = 0.001
Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 4/63 (6%)
Query: 1011 CPACQCN---GHSTCINNNVCEQCKNLTTGKQCQDCMPGYYG-DPTNGGQCTACTCSGHA 1066
C C CN TC + CK G C C PG + P N C++C C GH+
Sbjct: 427 CRPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHS 486
Query: 1067 NIC 1069
+C
Sbjct: 487 KVC 489
Score = 41.6 bits (96), Expect = 0.005
Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 15/90 (16%)
Query: 1011 CPACQCNGHSTCINNNVCEQ------CKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCS- 1063
C +C+C H + C C+ TG+ C C G++G G C AC CS
Sbjct: 914 CRSCKC--HPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKG--CRACRCSP 969
Query: 1064 -GHANI-CHLHTGKCFCTTKGIKGDQCQLC 1091
G A+ CH G C C G +G +C C
Sbjct: 970 LGAASAQCH-ENGTCVC-RPGFEGYKCDRC 997
Score = 34.3 bits (77), Expect = 0.85
Identities = 16/51 (31%), Positives = 22/51 (43%)
Query: 63 CERTGSCFSGRCVNSTCLCDPGWVGDQCQHCQGRFKLTEPSGYLTDGPINY 113
C G+ + N TC+C PG+ G +C C F LT + P Y
Sbjct: 967 CSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCY 1017
Score = 30.8 bits (68), Expect = 9.4
Identities = 18/67 (26%), Positives = 25/67 (37%), Gaps = 15/67 (22%)
Query: 233 CECDKYWKGEACDI-------------PYCKA-NCGSPDHGYCDLTGEKLCVCNDSWQGP 278
C C + G+ C+ PY C HG CD +CVC+ +GP
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGTCD-PNTGICVCSHHTEGP 731
Query: 279 DCSLNVP 285
C +P
Sbjct: 732 SCERCLP 738
>gi|50659098 regeneration associated muscle protease isoform a [Homo
sapiens]
Length = 737
Score = 63.5 bits (153), Expect = 1e-09
Identities = 45/171 (26%), Positives = 69/171 (40%), Gaps = 20/171 (11%)
Query: 81 CDPGWVGDQCQHCQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAVLRLRFNHFAT 140
C GW G C C + + L P+N C W I P V++LRF +
Sbjct: 116 CRAGWYGGDCMRCGQVLRAPKGQILLESYPLN----AHCEWTIHAKPGFVIQLRFVMLSL 171
Query: 141 E----CSWDHMYVYDGDSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAA 196
E C +D++ V DGD+ G I+ + GNE + + + F SD +
Sbjct: 172 EFDYMCQYDYVEVRDGDN--------RDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGS 223
Query: 197 YNLTGFNIFY-SINSCPNN-CSGHGKCTTSVSVPSQVYCECDKYWKGEACD 245
N GF+ Y I +C ++ C G C + C C + G+ C+
Sbjct: 224 KNFDGFHAIYEEITACSSSPCFHDGTCV--LDKAGSYKCACLAGYTGQRCE 272
Score = 31.6 bits (70), Expect = 5.5
Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 15/89 (16%)
Query: 52 ALYAQVS--QSKPCERTGSCFSGRCVNSTCLCDPGWVGDQCQHC----QGRFKLTEPSGY 105
A+Y +++ S PC G+C + + C C G+ G +C++ + + K +E S
Sbjct: 231 AIYEEITACSSSPCFHDGTCVLDKAGSYKCACLAGYTGQRCENLLEAGKSKIKASEDSLS 290
Query: 106 LTD--------GPIN-YKYKTKCTWLIEG 125
+ + GP+N Y+ T LI G
Sbjct: 291 VLEERNCSDPGGPVNGYQKITGGPGLING 319
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 63.2 bits (152), Expect = 2e-09
Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 11/91 (12%)
Query: 1011 CPACQCNGH------STCIN-NNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCS 1063
C CQCN + +C + + C CK TTG+ C+ C GY+GD + C C C+
Sbjct: 862 CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCN 921
Query: 1064 ---GHANICHLHTGKCFCTTKGIKGDQCQLC 1091
+ +CH TG+C C ++G +C C
Sbjct: 922 AGGSFSEVCHSQTGQCECRA-NVQGQRCDKC 951
Score = 62.4 bits (150), Expect = 3e-09
Identities = 71/278 (25%), Positives = 97/278 (34%), Gaps = 58/278 (20%)
Query: 863 CTSMANGLVCEK--------PVVSPNQNARPCKKPCSLRTS-----CSNCTSNGMECMWC 909
C G C+K P +++ +PC P ++ ++ C S G+ C C
Sbjct: 776 CKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGC 835
Query: 910 S------STKRCVDSNAYIISFPYGQCLEWQTATCS-------PQNCSGLRTCGQCLE-Q 955
+RC + S P G C Q C+ P +C L G CL +
Sbjct: 836 PVGYTGPRCERCAEGYFGQPSVPGGSC---QPCQCNDNLDFSIPGSCDSLS--GSCLICK 890
Query: 956 PG-----CGWCND--------PSNTGRGHCIEGSSRGPM--KLIGMHHSEMVLDTNLCPK 1000
PG C C D N C G S + G + C K
Sbjct: 891 PGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDK 950
Query: 1001 EKNYEWSFIQ---CPACQCNGHST----CINNNVCEQCKNLTTGKQCQDCMPGYYGDPTN 1053
K + C C CN + C + C C+ TGK+C C GY+
Sbjct: 951 CKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQC-WCQPGVTGKKCDRCAHGYFNFQEG 1009
Query: 1054 GGQCTACTCSGHANICHLHTGKCFCTTKGIKGDQCQLC 1091
G CTAC CS N C TG+C C I G++C C
Sbjct: 1010 G--CTACECSHLGNNCDPKTGRCICPPNTI-GEKCSKC 1044
Score = 59.7 bits (143), Expect = 2e-08
Identities = 34/104 (32%), Positives = 45/104 (43%), Gaps = 15/104 (14%)
Query: 1011 CPACQCNGHSTCINN--NVCEQCKNLTTGKQCQDCMPGYYGDPTNG--GQCTACTC---- 1062
C CQC GH+ ++ C CK+ T G C C+PG+YG+PT G C C C
Sbjct: 754 CEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNI 813
Query: 1063 --SGHANICHLHTGK---CFCTTKGIKGDQCQLCDSENRYVGNP 1101
+ + CHL C G G +C+ C Y G P
Sbjct: 814 PSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERC--AEGYFGQP 855
Score = 55.1 bits (131), Expect = 5e-07
Identities = 32/103 (31%), Positives = 46/103 (44%), Gaps = 14/103 (13%)
Query: 1011 CPACQCNGHSTCIN--NNVCEQCKNLTTGKQCQDCMPGYYGD----PTNGGQCTACTCSG 1064
C CQCNGHS+ + ++C+ C++ T G C+ C GYYG P + QC S
Sbjct: 1417 CVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISS 1476
Query: 1065 HANIC------HLHTGKCFCTTKGIKGDQCQLCDSENRYVGNP 1101
N L +C +G +G C+ C Y G+P
Sbjct: 1477 SNNFSPSCVAEGLDDYRCTACPRGYEGQYCERC--APGYTGSP 1517
Score = 53.1 bits (126), Expect = 2e-06
Identities = 47/186 (25%), Positives = 71/186 (38%), Gaps = 20/186 (10%)
Query: 911 STKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGRG 970
S + C+ + S P G+ TC P C+G + L P C + + G
Sbjct: 1390 SCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSS----LCDPETSICQNCQHHTAG 1445
Query: 971 HCIEGSSRGPMKLI-GMHHSEMVLDTNLCPKEKNYEWSFIQCPACQCNGHSTCINNNVCE 1029
E + G ++ G+ + L N+ P+C G +++ C
Sbjct: 1446 DFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFS------PSCVAEG----LDDYRCT 1495
Query: 1030 QCKNLTTGKQCQDCMPGYYGDPTN-GGQCTACTCSGHANI---CHLHTGKCFCTTKGIKG 1085
C G+ C+ C PGY G P N GG C C C + ++ C TG C C G G
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTC-RPGATG 1554
Query: 1086 DQCQLC 1091
+C C
Sbjct: 1555 RKCDGC 1560
Score = 48.5 bits (114), Expect = 4e-05
Identities = 52/228 (22%), Positives = 83/228 (36%), Gaps = 64/228 (28%)
Query: 881 QNARPCK--------KPCSLRTSCSNCTSN--GMECMWCSSTKRCVDSNAYIISFPYGQC 930
+N +PC+ + C +T C +N G C C + + S
Sbjct: 913 KNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQS------------ 960
Query: 931 LEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGRGHCIEGSSRGPMKLIGMHHSE 990
C P NC+ + E+ G WC P TG+
Sbjct: 961 ----ARGCVPCNCNSFGSKSFDCEESGQCWCQ-PGVTGKK-------------------- 995
Query: 991 MVLDTNLCPKEKNYEWSFIQ--CPACQCN--GHSTCINNNVCEQCKNLTTGKQCQDCMPG 1046
C + + ++F + C AC+C+ G++ C C T G++C C P
Sbjct: 996 -------CDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCI-CPPNTIGEKCSKCAPN 1047
Query: 1047 YYGDPTNGGQCTACTCSGHANI---CHLHTGKCFCTTKGIKGDQCQLC 1091
+G G C AC CS ++ C+++TG+C C K G +C C
Sbjct: 1048 TWGHSITTG-CKACNCSTVGSLDFQCNVNTGQCNCHPK-FSGAKCTEC 1093
Score = 47.0 bits (110), Expect = 1e-04
Identities = 29/108 (26%), Positives = 40/108 (37%), Gaps = 31/108 (28%)
Query: 1014 CQCNGHSTCI------NNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGG------QCTACT 1061
C C GH+ N + CE C++ T G C C PG++ P G +C AC
Sbjct: 287 CICYGHARACPLDPATNKSRCE-CEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACN 345
Query: 1062 CSGHANIC------------------HLHTGKCFCTTKGIKGDQCQLC 1091
C G A C ++ G C T+ G C+ C
Sbjct: 346 CHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETC 393
Score = 46.2 bits (108), Expect = 2e-04
Identities = 28/81 (34%), Positives = 33/81 (40%), Gaps = 5/81 (6%)
Query: 1027 VCEQCKNLTTGKQCQDCMPGY--YGDPTNGGQCTACTCSGHANICHLHTGKCFCTTKGIK 1084
VC QC TG C+ C P + GG C C C GHA C TG+C
Sbjct: 723 VC-QCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTG 781
Query: 1085 GDQCQLCDSENRYVGNPLRGT 1105
G C C + G P +GT
Sbjct: 782 GPYCDKC--LPGFYGEPTKGT 800
Score = 46.2 bits (108), Expect = 2e-04
Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 9/65 (13%)
Query: 1036 TGKQCQDCMPGYY------GDPTNG---GQCTACTCSGHANICHLHTGKCFCTTKGIKGD 1086
+G C+ C+PG+Y G T G G C C C+GH+++C T C GD
Sbjct: 1387 SGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGD 1446
Query: 1087 QCQLC 1091
C+ C
Sbjct: 1447 FCERC 1451
Score = 42.4 bits (98), Expect = 0.003
Identities = 57/258 (22%), Positives = 89/258 (34%), Gaps = 62/258 (24%)
Query: 852 RAAVAGLKANPCTSMANGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSNGMEC----- 906
RA V G + + C + GL Q+AR C PC+ C++ S +C
Sbjct: 940 RANVQGQRCDKCKAGTFGL----------QSARGCV-PCN----CNSFGSKSFDCEESGQ 984
Query: 907 MWCS---STKRCVDSNAYIISFPYGQCLEWQTA----TCSPQNCSGLRTCGQCLEQPGC- 958
WC + K+C +F G C + + C P+ G+C+ P
Sbjct: 985 CWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKT-------GRCICPPNTI 1037
Query: 959 -GWCNDPSNTGRGHCIE-GSSRGPMKLIGMHHSEMVLDTNLCPKEKNYE----------- 1005
C+ + GH I G +G + ++T C +
Sbjct: 1038 GEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGH 1097
Query: 1006 WSFIQCPACQC----NGHSTCINNNVCEQCKNLT---------TGKQCQDCMPGYYG-DP 1051
W++ +C C C +TC + C + T G C C PG +G D
Sbjct: 1098 WNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDA 1157
Query: 1052 TNGGQCTACTCSGHANIC 1069
N C++C C G C
Sbjct: 1158 KNPLGCSSCYCFGTTTQC 1175
Score = 37.4 bits (85), Expect = 0.10
Identities = 46/191 (24%), Positives = 69/191 (36%), Gaps = 15/191 (7%)
Query: 893 RTSCSNCTSNGM--ECMWCSST-KRCVDSNAYIISFPYGQCLEW--QTATCSPQNCSG-- 945
+T C C +G EC + + +R + N G C+ TA + + C+
Sbjct: 338 KTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGF 397
Query: 946 LRTCGQCLEQPG-CGWCN-DPSNTGRGHCIEGSSRGPMKLI-GMHHSEMVLDTNLCPKEK 1002
R G P C C+ DP + C++ L G H + C +
Sbjct: 398 FRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCA 457
Query: 1003 NYEWSFIQCPACQCNGHSTCINNNVCEQ---CKNLTTGKQCQDCMPGYYG-DPTNGGQCT 1058
+ C AC C+G + N + C CK G C C G++ N C
Sbjct: 458 RGYTGYPDCKACNCSGLGSK-NEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCD 516
Query: 1059 ACTCSGHANIC 1069
C CSG +N C
Sbjct: 517 ECFCSGVSNRC 527
Score = 36.6 bits (83), Expect = 0.17
Identities = 33/128 (25%), Positives = 40/128 (31%), Gaps = 39/128 (30%)
Query: 1010 QCPACQCNGHST--------------------CINNNVCEQCKNLTTGKQCQDCMPGYYG 1049
+C AC C+G + I VC C T G C+ C G++
Sbjct: 340 ECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFR 399
Query: 1050 ----DPTNGGQCTACTCS--GHAN-IC---------HLHTGKCFCTTKGIKGDQCQLCDS 1093
P C C C G N +C L G C C T G G C C
Sbjct: 400 PKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT-GFGGVSCDRC-- 456
Query: 1094 ENRYVGNP 1101
Y G P
Sbjct: 457 ARGYTGYP 464
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 63.2 bits (152), Expect = 2e-09
Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 11/91 (12%)
Query: 1011 CPACQCNGH------STCIN-NNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCS 1063
C CQCN + +C + + C CK TTG+ C+ C GY+GD + C C C+
Sbjct: 862 CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCN 921
Query: 1064 ---GHANICHLHTGKCFCTTKGIKGDQCQLC 1091
+ +CH TG+C C ++G +C C
Sbjct: 922 AGGSFSEVCHSQTGQCECRA-NVQGQRCDKC 951
Score = 62.4 bits (150), Expect = 3e-09
Identities = 71/278 (25%), Positives = 97/278 (34%), Gaps = 58/278 (20%)
Query: 863 CTSMANGLVCEK--------PVVSPNQNARPCKKPCSLRTS-----CSNCTSNGMECMWC 909
C G C+K P +++ +PC P ++ ++ C S G+ C C
Sbjct: 776 CKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGC 835
Query: 910 S------STKRCVDSNAYIISFPYGQCLEWQTATCS-------PQNCSGLRTCGQCLE-Q 955
+RC + S P G C Q C+ P +C L G CL +
Sbjct: 836 PVGYTGPRCERCAEGYFGQPSVPGGSC---QPCQCNDNLDFSIPGSCDSLS--GSCLICK 890
Query: 956 PG-----CGWCND--------PSNTGRGHCIEGSSRGPM--KLIGMHHSEMVLDTNLCPK 1000
PG C C D N C G S + G + C K
Sbjct: 891 PGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDK 950
Query: 1001 EKNYEWSFIQ---CPACQCNGHST----CINNNVCEQCKNLTTGKQCQDCMPGYYGDPTN 1053
K + C C CN + C + C C+ TGK+C C GY+
Sbjct: 951 CKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQC-WCQPGVTGKKCDRCAHGYFNFQEG 1009
Query: 1054 GGQCTACTCSGHANICHLHTGKCFCTTKGIKGDQCQLC 1091
G CTAC CS N C TG+C C I G++C C
Sbjct: 1010 G--CTACECSHLGNNCDPKTGRCICPPNTI-GEKCSKC 1044
Score = 59.7 bits (143), Expect = 2e-08
Identities = 34/104 (32%), Positives = 45/104 (43%), Gaps = 15/104 (14%)
Query: 1011 CPACQCNGHSTCINN--NVCEQCKNLTTGKQCQDCMPGYYGDPTNG--GQCTACTC---- 1062
C CQC GH+ ++ C CK+ T G C C+PG+YG+PT G C C C
Sbjct: 754 CEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNI 813
Query: 1063 --SGHANICHLHTGK---CFCTTKGIKGDQCQLCDSENRYVGNP 1101
+ + CHL C G G +C+ C Y G P
Sbjct: 814 PSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERC--AEGYFGQP 855
Score = 55.1 bits (131), Expect = 5e-07
Identities = 32/103 (31%), Positives = 46/103 (44%), Gaps = 14/103 (13%)
Query: 1011 CPACQCNGHSTCIN--NNVCEQCKNLTTGKQCQDCMPGYYGD----PTNGGQCTACTCSG 1064
C CQCNGHS+ + ++C+ C++ T G C+ C GYYG P + QC S
Sbjct: 1417 CVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISS 1476
Query: 1065 HANIC------HLHTGKCFCTTKGIKGDQCQLCDSENRYVGNP 1101
N L +C +G +G C+ C Y G+P
Sbjct: 1477 SNNFSPSCVAEGLDDYRCTACPRGYEGQYCERC--APGYTGSP 1517
Score = 53.1 bits (126), Expect = 2e-06
Identities = 47/186 (25%), Positives = 71/186 (38%), Gaps = 20/186 (10%)
Query: 911 STKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGRG 970
S + C+ + S P G+ TC P C+G + L P C + + G
Sbjct: 1390 SCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSS----LCDPETSICQNCQHHTAG 1445
Query: 971 HCIEGSSRGPMKLI-GMHHSEMVLDTNLCPKEKNYEWSFIQCPACQCNGHSTCINNNVCE 1029
E + G ++ G+ + L N+ P+C G +++ C
Sbjct: 1446 DFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFS------PSCVAEG----LDDYRCT 1495
Query: 1030 QCKNLTTGKQCQDCMPGYYGDPTN-GGQCTACTCSGHANI---CHLHTGKCFCTTKGIKG 1085
C G+ C+ C PGY G P N GG C C C + ++ C TG C C G G
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTC-RPGATG 1554
Query: 1086 DQCQLC 1091
+C C
Sbjct: 1555 RKCDGC 1560
Score = 48.5 bits (114), Expect = 4e-05
Identities = 52/228 (22%), Positives = 83/228 (36%), Gaps = 64/228 (28%)
Query: 881 QNARPCK--------KPCSLRTSCSNCTSN--GMECMWCSSTKRCVDSNAYIISFPYGQC 930
+N +PC+ + C +T C +N G C C + + S
Sbjct: 913 KNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQS------------ 960
Query: 931 LEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGRGHCIEGSSRGPMKLIGMHHSE 990
C P NC+ + E+ G WC P TG+
Sbjct: 961 ----ARGCVPCNCNSFGSKSFDCEESGQCWCQ-PGVTGKK-------------------- 995
Query: 991 MVLDTNLCPKEKNYEWSFIQ--CPACQCN--GHSTCINNNVCEQCKNLTTGKQCQDCMPG 1046
C + + ++F + C AC+C+ G++ C C T G++C C P
Sbjct: 996 -------CDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCI-CPPNTIGEKCSKCAPN 1047
Query: 1047 YYGDPTNGGQCTACTCSGHANI---CHLHTGKCFCTTKGIKGDQCQLC 1091
+G G C AC CS ++ C+++TG+C C K G +C C
Sbjct: 1048 TWGHSITTG-CKACNCSTVGSLDFQCNVNTGQCNCHPK-FSGAKCTEC 1093
Score = 47.0 bits (110), Expect = 1e-04
Identities = 29/108 (26%), Positives = 40/108 (37%), Gaps = 31/108 (28%)
Query: 1014 CQCNGHSTCI------NNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGG------QCTACT 1061
C C GH+ N + CE C++ T G C C PG++ P G +C AC
Sbjct: 287 CICYGHARACPLDPATNKSRCE-CEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACN 345
Query: 1062 CSGHANIC------------------HLHTGKCFCTTKGIKGDQCQLC 1091
C G A C ++ G C T+ G C+ C
Sbjct: 346 CHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETC 393
Score = 46.2 bits (108), Expect = 2e-04
Identities = 28/81 (34%), Positives = 33/81 (40%), Gaps = 5/81 (6%)
Query: 1027 VCEQCKNLTTGKQCQDCMPGY--YGDPTNGGQCTACTCSGHANICHLHTGKCFCTTKGIK 1084
VC QC TG C+ C P + GG C C C GHA C TG+C
Sbjct: 723 VC-QCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTG 781
Query: 1085 GDQCQLCDSENRYVGNPLRGT 1105
G C C + G P +GT
Sbjct: 782 GPYCDKC--LPGFYGEPTKGT 800
Score = 46.2 bits (108), Expect = 2e-04
Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 9/65 (13%)
Query: 1036 TGKQCQDCMPGYY------GDPTNG---GQCTACTCSGHANICHLHTGKCFCTTKGIKGD 1086
+G C+ C+PG+Y G T G G C C C+GH+++C T C GD
Sbjct: 1387 SGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGD 1446
Query: 1087 QCQLC 1091
C+ C
Sbjct: 1447 FCERC 1451
Score = 42.4 bits (98), Expect = 0.003
Identities = 57/258 (22%), Positives = 89/258 (34%), Gaps = 62/258 (24%)
Query: 852 RAAVAGLKANPCTSMANGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCTSNGMEC----- 906
RA V G + + C + GL Q+AR C PC+ C++ S +C
Sbjct: 940 RANVQGQRCDKCKAGTFGL----------QSARGCV-PCN----CNSFGSKSFDCEESGQ 984
Query: 907 MWCS---STKRCVDSNAYIISFPYGQCLEWQTA----TCSPQNCSGLRTCGQCLEQPGC- 958
WC + K+C +F G C + + C P+ G+C+ P
Sbjct: 985 CWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKT-------GRCICPPNTI 1037
Query: 959 -GWCNDPSNTGRGHCIE-GSSRGPMKLIGMHHSEMVLDTNLCPKEKNYE----------- 1005
C+ + GH I G +G + ++T C +
Sbjct: 1038 GEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGH 1097
Query: 1006 WSFIQCPACQC----NGHSTCINNNVCEQCKNLT---------TGKQCQDCMPGYYG-DP 1051
W++ +C C C +TC + C + T G C C PG +G D
Sbjct: 1098 WNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDA 1157
Query: 1052 TNGGQCTACTCSGHANIC 1069
N C++C C G C
Sbjct: 1158 KNPLGCSSCYCFGTTTQC 1175
Score = 37.4 bits (85), Expect = 0.10
Identities = 46/191 (24%), Positives = 69/191 (36%), Gaps = 15/191 (7%)
Query: 893 RTSCSNCTSNGM--ECMWCSST-KRCVDSNAYIISFPYGQCLEW--QTATCSPQNCSG-- 945
+T C C +G EC + + +R + N G C+ TA + + C+
Sbjct: 338 KTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGF 397
Query: 946 LRTCGQCLEQPG-CGWCN-DPSNTGRGHCIEGSSRGPMKLI-GMHHSEMVLDTNLCPKEK 1002
R G P C C+ DP + C++ L G H + C +
Sbjct: 398 FRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCA 457
Query: 1003 NYEWSFIQCPACQCNGHSTCINNNVCEQ---CKNLTTGKQCQDCMPGYYG-DPTNGGQCT 1058
+ C AC C+G + N + C CK G C C G++ N C
Sbjct: 458 RGYTGYPDCKACNCSGLGSK-NEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCD 516
Query: 1059 ACTCSGHANIC 1069
C CSG +N C
Sbjct: 517 ECFCSGVSNRC 527
Score = 36.6 bits (83), Expect = 0.17
Identities = 33/128 (25%), Positives = 40/128 (31%), Gaps = 39/128 (30%)
Query: 1010 QCPACQCNGHST--------------------CINNNVCEQCKNLTTGKQCQDCMPGYYG 1049
+C AC C+G + I VC C T G C+ C G++
Sbjct: 340 ECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFR 399
Query: 1050 ----DPTNGGQCTACTCS--GHAN-IC---------HLHTGKCFCTTKGIKGDQCQLCDS 1093
P C C C G N +C L G C C T G G C C
Sbjct: 400 PKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT-GFGGVSCDRC-- 456
Query: 1094 ENRYVGNP 1101
Y G P
Sbjct: 457 ARGYTGYP 464
>gi|98986457 host cell factor 1 [Homo sapiens]
Length = 2035
Score = 62.8 bits (151), Expect = 2e-09
Identities = 94/373 (25%), Positives = 142/373 (38%), Gaps = 95/373 (25%)
Query: 256 PDHGYCDLTGEKLCVC-NDSWQGPDCSLNVPSTES-YWILPNVKPFSPSVGRASHKAVLH 313
P HG+ + ++L V +G L+V +T + W +P V+ P G A++ V
Sbjct: 32 PRHGHRAVAIKELIVVFGGGNEGIVDELHVYNTATNQWFIPAVRGDIPP-GCAAYGFVCD 90
Query: 314 GKFMWVIGGYTFNYSSFQMVLNYNLESSIWN-----VGTPSRGP--LQRYGHSLALYQEN 366
G + V GG Y + L Y L++S W TP GP R GHS +L
Sbjct: 91 GTRLLVFGGMV-EYGKYSNDL-YELQASRWEWKRLKAKTPKNGPPPCPRLGHSFSLVGNK 148
Query: 367 IFMYGGRIETNDGNVTDELWVFNIHSQSWSTKTPTVLGHGQQYAVEGHSAHIMELDSRDV 426
+++GG ND S+ P L + +I+EL
Sbjct: 149 CYLFGGL--AND-------------SEDPKNNIPRYL----------NDLYILELRPGSG 183
Query: 427 VMIIIFGYSAIYGYTSSIQEYHISSNTWLVPETKGAIVQGGYGHTSVY----DEITKSIY 482
V+ W +P T G + HT+V D +
Sbjct: 184 VV------------------------AWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLV 219
Query: 483 VHGGYKALPGNKYGLVDDLYKYEVNTKTWTILKESGFA---RYLHSAVLINGAMLIFGG- 538
++GG + G + G DL+ +++T TW SG A R LHSA I M +FGG
Sbjct: 220 IYGG---MSGCRLG---DLWTLDIDTLTWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGW 273
Query: 539 ----------NTHN-DTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRF--GHS 585
TH + +N C + D +A W+ + L ++ R GH
Sbjct: 274 VPLVMDDVKVATHEKEWKCTNTLACLNLDTMA-------WETILMDTLEDNIPRARAGHC 326
Query: 586 AVVINGSMYIFGG 598
AV IN +YI+ G
Sbjct: 327 AVAINTRLYIWSG 339
Score = 51.6 bits (122), Expect = 5e-06
Identities = 73/290 (25%), Positives = 115/290 (39%), Gaps = 54/290 (18%)
Query: 345 VGTPSRGPLQRYGHSLALYQENIFMYGGRIETNDGNVTDELWVFNIHSQSWSTKTPTVLG 404
VG P R+GH +E I ++GG N+G + DEL V+N + W P V G
Sbjct: 23 VGWSGPVPRPRHGHRAVAIKELIVVFGGG---NEG-IVDELHVYNTATNQWFI--PAVRG 76
Query: 405 HGQQYAVEGHSAHIMELDSRDVVMIIIFGYSAIYGYTSSIQEYHISSNTWLVPETKGAIV 464
G +A+ D +++FG YG S+ Y + ++ W K
Sbjct: 77 D----IPPGCAAYGFVCDG---TRLLVFGGMVEYGKYSN-DLYELQASRWEWKRLKAKTP 128
Query: 465 QGG------YGHTSVYDEITKSIYVHGGY----KALPGNKYGLVDDLYKYEVNTKT---- 510
+ G GH+ + + Y+ GG + N ++DLY E+ +
Sbjct: 129 KNGPPPCPRLGHS--FSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRPGSGVVA 186
Query: 511 WTILKESGFA---RYLHSAVLIN------GAMLIFGGNTHNDTSLSNGAKCFSADFLAYD 561
W I G R H+AV+ ++I+GG + C D D
Sbjct: 187 WDIPITYGVLPPPRESHTAVVYTEKDNKKSKLVIYGGMSG----------CRLGDLWTLD 236
Query: 562 IACDEWKILPKPNLH--RDVNRFGHSAVVINGSMYIFGGFSSVLLNDILV 609
I W KP+L + R HSA I MY+FGG+ ++++D+ V
Sbjct: 237 IDTLTWN---KPSLSGVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVKV 283
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 62.4 bits (150), Expect = 3e-09
Identities = 63/215 (29%), Positives = 80/215 (37%), Gaps = 54/215 (25%)
Query: 903 GMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSPQNCSG-LRTCGQCLEQPGCGWC 961
G C C S R N PY C+ C+ C+G TC P G C
Sbjct: 698 GQFCEMCLSGYRRETPNLG----PYSPCV-----LCA---CNGHSETC-----DPETGVC 740
Query: 962 NDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNLCPKEKNYEWSFIQCPACQCNGHST 1021
N NT HC E S G ++ + T+ C C C G S+
Sbjct: 741 NCRDNTAGPHC-EKCSDG-------YYGDSTAGTSS------------DCQPCPCPGGSS 780
Query: 1022 CI-----NNNVCEQCKNLTTGKQCQDCMPGYYGDP--TNG--GQCTACTCSGH-----AN 1067
C VC C TTGK+C+ C GY+GDP NG C C CS +
Sbjct: 781 CAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVG 840
Query: 1068 ICHLHTGKCFCTTKGIKGDQCQLCDSENRYVGNPL 1102
C+ TG+C G C C ++ + GNPL
Sbjct: 841 NCNRLTGECLKCIYNTAGFYCDRC--KDGFFGNPL 873
Score = 54.7 bits (130), Expect = 6e-07
Identities = 33/92 (35%), Positives = 45/92 (48%), Gaps = 11/92 (11%)
Query: 1010 QCPACQCNGHSTCINNNVCE----QCKNL--TTGKQCQDCMPGYYGDPTNGGQCTACTCS 1063
+C AC CN + T + C QC+ L TG+ C C PG+Y + +G C C C
Sbjct: 880 KCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFY-NLQSGQGCERCDCH 938
Query: 1064 --GHAN-ICHLHTGKCFCTTKGIKGDQCQLCD 1092
G N C + TG+C C GI G C+ C+
Sbjct: 939 ALGSTNGQCDIRTGQCEC-QPGITGQHCERCE 969
Score = 50.8 bits (120), Expect = 9e-06
Identities = 45/215 (20%), Positives = 75/215 (34%), Gaps = 36/215 (16%)
Query: 890 CSLRTSCSNCTSNGMECMWCSSTKR-----CVDSNAYIISFPYGQCLEWQTATCSPQNCS 944
C S C N + + C+ C + P+ + + C P +C+
Sbjct: 286 CKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCN 345
Query: 945 GLRTCGQCLEQPGC-------GWC-NDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVLDTN 996
G +C P G C N NT HC R + ++E +
Sbjct: 346 GRSQ--ECYFDPELYRSTGHGGHCTNCQDNTDGAHC----ERCRENFFRLGNNEACSSCH 399
Query: 997 LCPKEKNYEWSFIQCPACQCNGHSTCINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQ 1056
P + + QC+ + C CK G +C C PG++ G +
Sbjct: 400 CSP---------VGSLSTQCDSYGRC-------SCKPGVMGDKCDRCQPGFHSLTEAGCR 443
Query: 1057 CTACTCSGHANICHLHTGKCFCTTKGIKGDQCQLC 1091
+C SG + C++ TG+C C ++G C+ C
Sbjct: 444 PCSCDPSGSIDECNIETGRCVC-KDNVEGFNCERC 477
Score = 48.9 bits (115), Expect = 3e-05
Identities = 58/261 (22%), Positives = 84/261 (32%), Gaps = 72/261 (27%)
Query: 863 CTSMANGLVCEKPVVSPNQNARPC-----KKPCSLRTSCSNCTSN--GMECMWCSSTKRC 915
C +G E P + P C + C T NC N G C CS
Sbjct: 701 CEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVCNCRDNTAGPHCEKCS----- 755
Query: 916 VDSNAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGRGHCI-- 973
+ Y YG ++ C P C G +C + N P+ T C
Sbjct: 756 ---DGY-----YGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELC 807
Query: 974 -EG------SSRGPMKLIGMHHSEMVLDTNLCPKEKNYEWSFIQCPACQCNGH--STCIN 1024
+G GP++L C CQC+ + +
Sbjct: 808 DDGYFGDPLGRNGPVRL---------------------------CRLCQCSDNIDPNAVG 840
Query: 1025 N-----NVCEQCKNLTTGKQCQDCMPGYYGD---PTNGGQCTACTCSGHANI-----CHL 1071
N C +C T G C C G++G+ P +C AC C+ + + C+
Sbjct: 841 NCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNP 900
Query: 1072 HTGKCFCTTKGIKGDQCQLCD 1092
TG+C C + G C CD
Sbjct: 901 VTGQCECLPH-VTGQDCGACD 920
Score = 43.1 bits (100), Expect = 0.002
Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 6/64 (9%)
Query: 1011 CPACQCNGHSTCINNNV----CEQCKNLTTGKQCQDCMPGYYG-DPTNGGQCTACTCSGH 1065
C C C+ + N+ C CK+ G C+ C PG++ + +N CT C C GH
Sbjct: 442 CRPCSCDPSGSIDECNIETGRCV-CKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGH 500
Query: 1066 ANIC 1069
+++C
Sbjct: 501 SSVC 504
Score = 40.4 bits (93), Expect = 0.012
Identities = 25/95 (26%), Positives = 40/95 (42%), Gaps = 13/95 (13%)
Query: 1011 CPACQCNGHSTCINNNVCE------QCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTC-- 1062
C C C H+ N C+ +C+ TG+ C+ C ++G G C C C
Sbjct: 932 CERCDC--HALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEG--CKPCDCHP 987
Query: 1063 SGHANICHLHTGKCFCTTKGIKGDQCQLCDSENRY 1097
G ++ G+C C +G G++C C+ Y
Sbjct: 988 EGSLSLQCKDDGRCEC-REGFVGNRCDQCEENYFY 1021
Score = 30.8 bits (68), Expect = 9.4
Identities = 16/40 (40%), Positives = 19/40 (47%), Gaps = 1/40 (2%)
Query: 63 CERTGSCFSGRCVNSTCLCDPGWVGDQCQHCQ-GRFKLTE 101
C GS + C C PG +GD+C CQ G LTE
Sbjct: 400 CSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTE 439
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 62.0 bits (149), Expect = 4e-09
Identities = 61/249 (24%), Positives = 103/249 (41%), Gaps = 38/249 (15%)
Query: 93 CQGRFKLTEPSGYLTDG--PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVY 150
C G F + PSG + P YK C W+IE P +++ F F TE ++D + V+
Sbjct: 855 CGGHF--SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVH 912
Query: 151 DGDSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFY-SIN 209
DG ++ +PL+ +G VP+ + ++S + L F +D + + GF I Y S+
Sbjct: 913 DGPNLLSPLLGSYNGTQVPQF--------LFSSSNFIYLLFTTDNSRSNNGFKIHYESVT 964
Query: 210 SCPNNCSGHG------KCTTSVSVPSQVYCECDKYWKGEACDIPYCKANCGSPDHGYCDL 263
+C G + S+ S V CD ++ + C+ N H +
Sbjct: 965 VNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKN-----HWWSHP 1019
Query: 264 TGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGY 323
+C +GP ++ P ++ PN S+ V HGK G
Sbjct: 1020 LPTCDALCGGDVRGPSGTILSPGYPEFY--PN------SLNCTWTVDVTHGK------GV 1065
Query: 324 TFNYSSFQM 332
FN+ +F +
Sbjct: 1066 QFNFHTFHL 1074
Score = 54.7 bits (130), Expect = 6e-07
Identities = 37/119 (31%), Positives = 53/119 (44%), Gaps = 13/119 (10%)
Query: 100 TEPSGYLT--DGPINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYA 157
T P G + D P Y C W I P + + L FN F E +D + V DGDS +
Sbjct: 686 TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPES 745
Query: 158 PLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSI---NSCPN 213
P++ +G VP + + S L F +D + + GFNI Y+ N CP+
Sbjct: 746 PILGTFTGAEVPS--------HLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPD 796
Score = 54.7 bits (130), Expect = 6e-07
Identities = 38/116 (32%), Positives = 57/116 (49%), Gaps = 9/116 (7%)
Query: 93 CQGRFKLTEPSGYLTDG-PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYD 151
C GRFK L+ G P Y +C W+IE P ++ L+F F TE S D + V+D
Sbjct: 1374 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWD 1433
Query: 152 GDSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYS 207
G L+ +SG ++PE G + +VT + F +D + +GF I +S
Sbjct: 1434 GPPENDMLLKEISGSLIPE--GIHSTLNIVT------IQFDTDFYISKSGFAIQFS 1481
Score = 54.7 bits (130), Expect = 6e-07
Identities = 49/185 (26%), Positives = 74/185 (40%), Gaps = 32/185 (17%)
Query: 99 LTEPSGYLTDG--PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIY 156
LT SG++ P Y + C W I + V+ L F F+ E ++D +Y+YDG
Sbjct: 1552 LTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSN 1611
Query: 157 APLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSI---NSC-- 211
+PLI +PE + ++S L F SD + + TGF++ Y SC
Sbjct: 1612 SPLIGSFQDSKLPE--------RIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFD 1663
Query: 212 PNNCSGHGKCTTSVSVPSQV--YCECDKYWKGEAC---------------DIPYCKANCG 254
P N + + S V YC+ +G + +P C A CG
Sbjct: 1664 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCG 1723
Query: 255 SPDHG 259
S G
Sbjct: 1724 SRSTG 1728
Score = 53.1 bits (126), Expect = 2e-06
Identities = 44/165 (26%), Positives = 67/165 (40%), Gaps = 28/165 (16%)
Query: 110 PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVP 169
P Y C W I A ++++ FATE +WD + YDG AP + SG +P
Sbjct: 1916 PEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIP 1975
Query: 170 EIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYS---INSC--PNNCSGHGKCTTS 224
+ + +TS L+F SD + + GF++ Y+ ++SC P S K
Sbjct: 1976 HL--------LNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDR 2027
Query: 225 VSVPSQVYCECDKYWKGEA---------------CDIPYCKANCG 254
V V +CD+ + + IP C A CG
Sbjct: 2028 YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCG 2072
Score = 49.7 bits (117), Expect = 2e-05
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 11/107 (10%)
Query: 110 PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVP 169
P NY CTW I + L+F +F+TE D++ V G S + +I LSG +P
Sbjct: 2088 PGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIP 2147
Query: 170 EIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIF---YSINSCPN 213
+ +T+ L+F SD + N GF+I Y + SCP+
Sbjct: 2148 S--------SLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPD 2186
Score = 44.7 bits (104), Expect = 6e-04
Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 11/107 (10%)
Query: 110 PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVP 169
P Y CTW+I +++ F FA E +D++ +YDG L+G +P
Sbjct: 42 PYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLP 101
Query: 170 EIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFY---SINSCPN 213
P V +T L SD A + GF ++Y +SC N
Sbjct: 102 --------PPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 140
Score = 43.5 bits (101), Expect = 0.001
Identities = 27/111 (24%), Positives = 47/111 (42%), Gaps = 12/111 (10%)
Query: 110 PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVP 169
P Y CTW I P + L F F E +D++ + + P LSG+ +P
Sbjct: 218 PNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSE----PPTIWLSGMNIP 273
Query: 170 EIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSGHGK 220
P +++ + LHF +D+ + GF+ Y +S + + G+
Sbjct: 274 --------PPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGE 316
Score = 40.8 bits (94), Expect = 0.009
Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 14/123 (11%)
Query: 93 CQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDG 152
C G + Y P Y C WL+ P + + F TE +D + V+DG
Sbjct: 2243 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDG 2302
Query: 153 DSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIF----YSI 208
+P I S GN + V +TS L+ F SD + +GF + Y +
Sbjct: 2303 PDQNSPQIGQFS--------GNTALESVYSTSNQILIKFHSD--FTTSGFFVLSYHAYQL 2352
Query: 209 NSC 211
C
Sbjct: 2353 RVC 2355
Score = 38.9 bits (89), Expect = 0.034
Identities = 39/155 (25%), Positives = 63/155 (40%), Gaps = 16/155 (10%)
Query: 110 PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVP 169
P +Y C W I + + F TE +D + VYDG +I +P++ LS
Sbjct: 2435 PDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLS----- 2489
Query: 170 EIRGNETVPEVVTTSGY-ALLHFFSDAAYNLTGFNIFYSINSCPNNCS---GHGKCTTSV 225
G+ + +T++G+ L + +D N GF I Y C S G+ T
Sbjct: 2490 ---GDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGG 2546
Query: 226 SVPSQVYCECDKYWKGEACDIPYCKANCGSPDHGY 260
+ S V CD+ ++ + A C +GY
Sbjct: 2547 QLNSVVRWACDRGFR----LVGKSSAVCRKSSYGY 2577
Score = 36.6 bits (83), Expect = 0.17
Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 8/108 (7%)
Query: 102 PSG-YLTDG-PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPL 159
PSG L+ G P Y CTW ++ ++ F+ F E D++ + + S PL
Sbjct: 1034 PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPL 1093
Query: 160 IAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYS 207
A L+G +P T+ + + A L F SD + + GFNI +S
Sbjct: 1094 -ARLTGSDLP-----PTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1135
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 62.0 bits (149), Expect = 4e-09
Identities = 61/249 (24%), Positives = 103/249 (41%), Gaps = 38/249 (15%)
Query: 93 CQGRFKLTEPSGYLTDG--PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVY 150
C G F + PSG + P YK C W+IE P +++ F F TE ++D + V+
Sbjct: 791 CGGHF--SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVH 848
Query: 151 DGDSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFY-SIN 209
DG ++ +PL+ +G VP+ + ++S + L F +D + + GF I Y S+
Sbjct: 849 DGPNLLSPLLGSYNGTQVPQF--------LFSSSNFIYLLFTTDNSRSNNGFKIHYESVT 900
Query: 210 SCPNNCSGHG------KCTTSVSVPSQVYCECDKYWKGEACDIPYCKANCGSPDHGYCDL 263
+C G + S+ S V CD ++ + C+ N H +
Sbjct: 901 VNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKN-----HWWSHP 955
Query: 264 TGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGY 323
+C +GP ++ P ++ PN S+ V HGK G
Sbjct: 956 LPTCDALCGGDVRGPSGTILSPGYPEFY--PN------SLNCTWTVDVTHGK------GV 1001
Query: 324 TFNYSSFQM 332
FN+ +F +
Sbjct: 1002 QFNFHTFHL 1010
Score = 54.7 bits (130), Expect = 6e-07
Identities = 37/119 (31%), Positives = 53/119 (44%), Gaps = 13/119 (10%)
Query: 100 TEPSGYLT--DGPINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYA 157
T P G + D P Y C W I P + + L FN F E +D + V DGDS +
Sbjct: 622 TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPES 681
Query: 158 PLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSI---NSCPN 213
P++ +G VP + + S L F +D + + GFNI Y+ N CP+
Sbjct: 682 PILGTFTGAEVPS--------HLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPD 732
Score = 54.7 bits (130), Expect = 6e-07
Identities = 38/116 (32%), Positives = 57/116 (49%), Gaps = 9/116 (7%)
Query: 93 CQGRFKLTEPSGYLTDG-PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYD 151
C GRFK L+ G P Y +C W+IE P ++ L+F F TE S D + V+D
Sbjct: 1310 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWD 1369
Query: 152 GDSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYS 207
G L+ +SG ++PE G + +VT + F +D + +GF I +S
Sbjct: 1370 GPPENDMLLKEISGSLIPE--GIHSTLNIVT------IQFDTDFYISKSGFAIQFS 1417
Score = 54.7 bits (130), Expect = 6e-07
Identities = 49/185 (26%), Positives = 74/185 (40%), Gaps = 32/185 (17%)
Query: 99 LTEPSGYLTDG--PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIY 156
LT SG++ P Y + C W I + V+ L F F+ E ++D +Y+YDG
Sbjct: 1488 LTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSN 1547
Query: 157 APLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSI---NSC-- 211
+PLI +PE + ++S L F SD + + TGF++ Y SC
Sbjct: 1548 SPLIGSFQDSKLPE--------RIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFD 1599
Query: 212 PNNCSGHGKCTTSVSVPSQV--YCECDKYWKGEAC---------------DIPYCKANCG 254
P N + + S V YC+ +G + +P C A CG
Sbjct: 1600 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCG 1659
Query: 255 SPDHG 259
S G
Sbjct: 1660 SRSTG 1664
Score = 53.1 bits (126), Expect = 2e-06
Identities = 44/165 (26%), Positives = 67/165 (40%), Gaps = 28/165 (16%)
Query: 110 PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVP 169
P Y C W I A ++++ FATE +WD + YDG AP + SG +P
Sbjct: 1852 PEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIP 1911
Query: 170 EIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYS---INSC--PNNCSGHGKCTTS 224
+ + +TS L+F SD + + GF++ Y+ ++SC P S K
Sbjct: 1912 HL--------LNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDR 1963
Query: 225 VSVPSQVYCECDKYWKGEA---------------CDIPYCKANCG 254
V V +CD+ + + IP C A CG
Sbjct: 1964 YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCG 2008
Score = 49.7 bits (117), Expect = 2e-05
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 11/107 (10%)
Query: 110 PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVP 169
P NY CTW I + L+F +F+TE D++ V G S + +I LSG +P
Sbjct: 2024 PGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIP 2083
Query: 170 EIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIF---YSINSCPN 213
+ +T+ L+F SD + N GF+I Y + SCP+
Sbjct: 2084 S--------SLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPD 2122
Score = 44.7 bits (104), Expect = 6e-04
Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 11/107 (10%)
Query: 110 PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVP 169
P Y CTW+I +++ F FA E +D++ +YDG L+G +P
Sbjct: 82 PYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLP 141
Query: 170 EIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFY---SINSCPN 213
P V +T L SD A + GF ++Y +SC N
Sbjct: 142 --------PPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 180
Score = 43.5 bits (101), Expect = 0.001
Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 12/99 (12%)
Query: 110 PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVP 169
P Y CTW I P + L F F E +D++ + + P LSG+ +P
Sbjct: 258 PNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSE----PPTIWLSGMNIP 313
Query: 170 EIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSI 208
P +++ + LHF +D+ + GF+ Y +
Sbjct: 314 --------PPIISNKNWLRLHFVTDSNHRYRGFSAPYQV 344
Score = 40.8 bits (94), Expect = 0.009
Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 14/123 (11%)
Query: 93 CQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDG 152
C G + Y P Y C WL+ P + + F TE +D + V+DG
Sbjct: 2179 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDG 2238
Query: 153 DSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIF----YSI 208
+P I S GN + V +TS L+ F SD + +GF + Y +
Sbjct: 2239 PDQNSPQIGQFS--------GNTALESVYSTSNQILIKFHSD--FTTSGFFVLSYHAYQL 2288
Query: 209 NSC 211
C
Sbjct: 2289 RVC 2291
Score = 38.9 bits (89), Expect = 0.034
Identities = 39/155 (25%), Positives = 63/155 (40%), Gaps = 16/155 (10%)
Query: 110 PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVP 169
P +Y C W I + + F TE +D + VYDG +I +P++ LS
Sbjct: 2371 PDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLS----- 2425
Query: 170 EIRGNETVPEVVTTSGY-ALLHFFSDAAYNLTGFNIFYSINSCPNNCS---GHGKCTTSV 225
G+ + +T++G+ L + +D N GF I Y C S G+ T
Sbjct: 2426 ---GDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGG 2482
Query: 226 SVPSQVYCECDKYWKGEACDIPYCKANCGSPDHGY 260
+ S V CD+ ++ + A C +GY
Sbjct: 2483 QLNSVVRWACDRGFR----LVGKSSAVCRKSSYGY 2513
Score = 36.6 bits (83), Expect = 0.17
Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 8/108 (7%)
Query: 102 PSG-YLTDG-PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPL 159
PSG L+ G P Y CTW ++ ++ F+ F E D++ + + S PL
Sbjct: 970 PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPL 1029
Query: 160 IAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYS 207
A L+G +P T+ + + A L F SD + + GFNI +S
Sbjct: 1030 -ARLTGSDLP-----PTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1071
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 62.0 bits (149), Expect = 4e-09
Identities = 61/249 (24%), Positives = 103/249 (41%), Gaps = 38/249 (15%)
Query: 93 CQGRFKLTEPSGYLTDG--PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVY 150
C G F + PSG + P YK C W+IE P +++ F F TE ++D + V+
Sbjct: 895 CGGHF--SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVH 952
Query: 151 DGDSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFY-SIN 209
DG ++ +PL+ +G VP+ + ++S + L F +D + + GF I Y S+
Sbjct: 953 DGPNLLSPLLGSYNGTQVPQF--------LFSSSNFIYLLFTTDNSRSNNGFKIHYESVT 1004
Query: 210 SCPNNCSGHG------KCTTSVSVPSQVYCECDKYWKGEACDIPYCKANCGSPDHGYCDL 263
+C G + S+ S V CD ++ + C+ N H +
Sbjct: 1005 VNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKN-----HWWSHP 1059
Query: 264 TGEKLCVCNDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGY 323
+C +GP ++ P ++ PN S+ V HGK G
Sbjct: 1060 LPTCDALCGGDVRGPSGTILSPGYPEFY--PN------SLNCTWTVDVTHGK------GV 1105
Query: 324 TFNYSSFQM 332
FN+ +F +
Sbjct: 1106 QFNFHTFHL 1114
Score = 54.7 bits (130), Expect = 6e-07
Identities = 37/119 (31%), Positives = 53/119 (44%), Gaps = 13/119 (10%)
Query: 100 TEPSGYLT--DGPINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYA 157
T P G + D P Y C W I P + + L FN F E +D + V DGDS +
Sbjct: 726 TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPES 785
Query: 158 PLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSI---NSCPN 213
P++ +G VP + + S L F +D + + GFNI Y+ N CP+
Sbjct: 786 PILGTFTGAEVPS--------HLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPD 836
Score = 54.7 bits (130), Expect = 6e-07
Identities = 38/116 (32%), Positives = 57/116 (49%), Gaps = 9/116 (7%)
Query: 93 CQGRFKLTEPSGYLTDG-PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYD 151
C GRFK L+ G P Y +C W+IE P ++ L+F F TE S D + V+D
Sbjct: 1414 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWD 1473
Query: 152 GDSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYS 207
G L+ +SG ++PE G + +VT + F +D + +GF I +S
Sbjct: 1474 GPPENDMLLKEISGSLIPE--GIHSTLNIVT------IQFDTDFYISKSGFAIQFS 1521
Score = 54.7 bits (130), Expect = 6e-07
Identities = 49/185 (26%), Positives = 74/185 (40%), Gaps = 32/185 (17%)
Query: 99 LTEPSGYLTDG--PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIY 156
LT SG++ P Y + C W I + V+ L F F+ E ++D +Y+YDG
Sbjct: 1592 LTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSN 1651
Query: 157 APLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSI---NSC-- 211
+PLI +PE + ++S L F SD + + TGF++ Y SC
Sbjct: 1652 SPLIGSFQDSKLPE--------RIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFD 1703
Query: 212 PNNCSGHGKCTTSVSVPSQV--YCECDKYWKGEAC---------------DIPYCKANCG 254
P N + + S V YC+ +G + +P C A CG
Sbjct: 1704 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCG 1763
Query: 255 SPDHG 259
S G
Sbjct: 1764 SRSTG 1768
Score = 53.1 bits (126), Expect = 2e-06
Identities = 44/165 (26%), Positives = 67/165 (40%), Gaps = 28/165 (16%)
Query: 110 PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVP 169
P Y C W I A ++++ FATE +WD + YDG AP + SG +P
Sbjct: 1956 PEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIP 2015
Query: 170 EIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYS---INSC--PNNCSGHGKCTTS 224
+ + +TS L+F SD + + GF++ Y+ ++SC P S K
Sbjct: 2016 HL--------LNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDR 2067
Query: 225 VSVPSQVYCECDKYWKGEA---------------CDIPYCKANCG 254
V V +CD+ + + IP C A CG
Sbjct: 2068 YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCG 2112
Score = 49.7 bits (117), Expect = 2e-05
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 11/107 (10%)
Query: 110 PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVP 169
P NY CTW I + L+F +F+TE D++ V G S + +I LSG +P
Sbjct: 2128 PGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIP 2187
Query: 170 EIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIF---YSINSCPN 213
+ +T+ L+F SD + N GF+I Y + SCP+
Sbjct: 2188 S--------SLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPD 2226
Score = 44.7 bits (104), Expect = 6e-04
Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 11/107 (10%)
Query: 110 PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVP 169
P Y CTW+I +++ F FA E +D++ +YDG L+G +P
Sbjct: 82 PYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLP 141
Query: 170 EIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFY---SINSCPN 213
P V +T L SD A + GF ++Y +SC N
Sbjct: 142 --------PPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN 180
Score = 43.5 bits (101), Expect = 0.001
Identities = 27/111 (24%), Positives = 47/111 (42%), Gaps = 12/111 (10%)
Query: 110 PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVP 169
P Y CTW I P + L F F E +D++ + + P LSG+ +P
Sbjct: 258 PNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSE----PPTIWLSGMNIP 313
Query: 170 EIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYSINSCPNNCSGHGK 220
P +++ + LHF +D+ + GF+ Y +S + + G+
Sbjct: 314 --------PPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGE 356
Score = 40.8 bits (94), Expect = 0.009
Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 14/123 (11%)
Query: 93 CQGRFKLTEPSGYLTDGPINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDG 152
C G + Y P Y C WL+ P + + F TE +D + V+DG
Sbjct: 2283 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDG 2342
Query: 153 DSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIF----YSI 208
+P I S GN + V +TS L+ F SD + +GF + Y +
Sbjct: 2343 PDQNSPQIGQFS--------GNTALESVYSTSNQILIKFHSD--FTTSGFFVLSYHAYQL 2392
Query: 209 NSC 211
C
Sbjct: 2393 RVC 2395
Score = 38.9 bits (89), Expect = 0.034
Identities = 39/155 (25%), Positives = 63/155 (40%), Gaps = 16/155 (10%)
Query: 110 PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPLIAVLSGLIVP 169
P +Y C W I + + F TE +D + VYDG +I +P++ LS
Sbjct: 2475 PDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLS----- 2529
Query: 170 EIRGNETVPEVVTTSGY-ALLHFFSDAAYNLTGFNIFYSINSCPNNCS---GHGKCTTSV 225
G+ + +T++G+ L + +D N GF I Y C S G+ T
Sbjct: 2530 ---GDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGG 2586
Query: 226 SVPSQVYCECDKYWKGEACDIPYCKANCGSPDHGY 260
+ S V CD+ ++ + A C +GY
Sbjct: 2587 QLNSVVRWACDRGFR----LVGKSSAVCRKSSYGY 2617
Score = 36.6 bits (83), Expect = 0.17
Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 8/108 (7%)
Query: 102 PSG-YLTDG-PINYKYKTKCTWLIEGYPNAVLRLRFNHFATECSWDHMYVYDGDSIYAPL 159
PSG L+ G P Y CTW ++ ++ F+ F E D++ + + S PL
Sbjct: 1074 PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPL 1133
Query: 160 IAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNIFYS 207
A L+G +P T+ + + A L F SD + + GFNI +S
Sbjct: 1134 -ARLTGSDLP-----PTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1175
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 61.6 bits (148), Expect = 5e-09
Identities = 35/104 (33%), Positives = 49/104 (47%), Gaps = 14/104 (13%)
Query: 1010 QCPACQCNGHST-CINNN-VCEQCKNLTTGKQCQDCMPGYYGDPTNGGQ--CTACTC--- 1062
+C C CNG+S C++ + C C+ TTG+ C+ C+ GY GD G C C C
Sbjct: 78 ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
Query: 1063 --SGHANICHLHTG--KCFCTTKGIKGDQCQLCDSENRYVGNPL 1102
+ A C+ G +C C + G C+ C Y GNPL
Sbjct: 138 HLANFAESCYRKNGAVRCIC-NENYAGPNCERC--APGYYGNPL 178
Score = 53.5 bits (127), Expect = 1e-06
Identities = 27/74 (36%), Positives = 32/74 (43%), Gaps = 10/74 (13%)
Query: 1011 CPACQCNGHST-------CIN-NNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTC 1062
C C C+G+S C C C TTG +C+ C PGYYGD C C C
Sbjct: 184 CKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC 243
Query: 1063 SGHANICHLHTGKC 1076
G C TG+C
Sbjct: 244 GG--GPCDSVTGEC 255
Score = 51.2 bits (121), Expect = 7e-06
Identities = 44/169 (26%), Positives = 64/169 (37%), Gaps = 38/169 (22%)
Query: 938 CSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNL 997
C P +C+G +CL+ G G+C HC ++ H E LD +
Sbjct: 79 CVPCDCNG--NSNECLD--GSGYCV--------HCQRNTTG--------EHCEKCLDGYI 118
Query: 998 CPKEKNYEWSFIQCPACQC------NGHSTCINNNVCEQC--KNLTTGKQCQDCMPGYYG 1049
+ C C C N +C N +C G C+ C PGYYG
Sbjct: 119 GDSIRGAPQF---CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG 175
Query: 1050 DPTN-GGQCTACTCSGHAN------ICHLHTGKCFCTTKGIKGDQCQLC 1091
+P G C C CSG+++ C TG+C + G +C+ C
Sbjct: 176 NPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
Score = 42.0 bits (97), Expect = 0.004
Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 4/64 (6%)
Query: 1041 QDCMPGYYGDPTNGGQCTACTCSGHANICHLHTGKCFCTTKGIKGDQCQLCDSENRYVGN 1100
+ C G++ T G+C C C+G++N C +G C + G+ C+ C + Y+G+
Sbjct: 65 EKCNAGFFH--TLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKC--LDGYIGD 120
Query: 1101 PLRG 1104
+RG
Sbjct: 121 SIRG 124
>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
Length = 1823
Score = 61.6 bits (148), Expect = 5e-09
Identities = 35/104 (33%), Positives = 49/104 (47%), Gaps = 14/104 (13%)
Query: 1010 QCPACQCNGHST-CINNN-VCEQCKNLTTGKQCQDCMPGYYGDPTNGGQ--CTACTC--- 1062
+C C CNG+S C++ + C C+ TTG+ C+ C+ GY GD G C C C
Sbjct: 78 ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
Query: 1063 --SGHANICHLHTG--KCFCTTKGIKGDQCQLCDSENRYVGNPL 1102
+ A C+ G +C C + G C+ C Y GNPL
Sbjct: 138 HLANFAESCYRKNGAVRCIC-NENYAGPNCERC--APGYYGNPL 178
Score = 53.5 bits (127), Expect = 1e-06
Identities = 27/74 (36%), Positives = 32/74 (43%), Gaps = 10/74 (13%)
Query: 1011 CPACQCNGHST-------CIN-NNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTC 1062
C C C+G+S C C C TTG +C+ C PGYYGD C C C
Sbjct: 184 CKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC 243
Query: 1063 SGHANICHLHTGKC 1076
G C TG+C
Sbjct: 244 GG--GPCDSVTGEC 255
Score = 51.2 bits (121), Expect = 7e-06
Identities = 44/169 (26%), Positives = 64/169 (37%), Gaps = 38/169 (22%)
Query: 938 CSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNL 997
C P +C+G +CL+ G G+C HC ++ H E LD +
Sbjct: 79 CVPCDCNG--NSNECLD--GSGYCV--------HCQRNTTG--------EHCEKCLDGYI 118
Query: 998 CPKEKNYEWSFIQCPACQC------NGHSTCINNNVCEQC--KNLTTGKQCQDCMPGYYG 1049
+ C C C N +C N +C G C+ C PGYYG
Sbjct: 119 GDSIRGAPQF---CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG 175
Query: 1050 DPTN-GGQCTACTCSGHAN------ICHLHTGKCFCTTKGIKGDQCQLC 1091
+P G C C CSG+++ C TG+C + G +C+ C
Sbjct: 176 NPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
Score = 42.0 bits (97), Expect = 0.004
Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 4/64 (6%)
Query: 1041 QDCMPGYYGDPTNGGQCTACTCSGHANICHLHTGKCFCTTKGIKGDQCQLCDSENRYVGN 1100
+ C G++ T G+C C C+G++N C +G C + G+ C+ C + Y+G+
Sbjct: 65 EKCNAGFFH--TLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKC--LDGYIGD 120
Query: 1101 PLRG 1104
+RG
Sbjct: 121 SIRG 124
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,322,395
Number of Sequences: 37866
Number of extensions: 3121152
Number of successful extensions: 11987
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 112
Number of HSP's successfully gapped in prelim test: 317
Number of HSP's that attempted gapping in prelim test: 8718
Number of HSP's gapped (non-prelim): 2858
length of query: 1379
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1264
effective length of database: 13,892,928
effective search space: 17560660992
effective search space used: 17560660992
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.