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Search of human proteins with 45827755
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45827755 transforming, acidic coiled-coil containing protein
2 isoform b [Homo sapiens]
(1094 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45827755 transforming, acidic coiled-coil containing protein ... 2165 0.0
gi|150418009 transforming, acidic coiled-coil containing protein... 2048 0.0
gi|11119414 transforming, acidic coiled-coil containing protein ... 1986 0.0
gi|45827753 transforming, acidic coiled-coil containing protein ... 1917 0.0
gi|170763517 transforming, acidic coiled-coil containing protein... 306 5e-83
gi|226246618 transforming, acidic coiled-coil containing protein... 300 4e-81
gi|170763519 transforming, acidic coiled-coil containing protein... 298 2e-80
gi|5454102 transforming, acidic coiled-coil containing protein 3... 211 3e-54
gi|163965366 nascent polypeptide-associated complex alpha subuni... 83 1e-15
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 82 4e-15
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 82 4e-15
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 82 4e-15
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 82 4e-15
gi|110349719 titin isoform N2-A [Homo sapiens] 70 8e-12
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 70 8e-12
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 67 7e-11
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 67 7e-11
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 67 1e-10
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 67 1e-10
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 65 3e-10
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 65 3e-10
gi|91982772 mucin 17 [Homo sapiens] 65 5e-10
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 64 8e-10
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 64 1e-09
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 63 1e-09
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 61 7e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 60 9e-09
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 60 9e-09
gi|58530840 desmoplakin isoform I [Homo sapiens] 59 2e-08
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 59 3e-08
>gi|45827755 transforming, acidic coiled-coil containing protein 2
isoform b [Homo sapiens]
Length = 1094
Score = 2165 bits (5611), Expect = 0.0
Identities = 1094/1094 (100%), Positives = 1094/1094 (100%)
Query: 1 MGNENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPA 60
MGNENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPA
Sbjct: 1 MGNENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPA 60
Query: 61 APADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPE 120
APADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPE
Sbjct: 61 APADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPE 120
Query: 121 VIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSG 180
VIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSG
Sbjct: 121 VIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSG 180
Query: 181 TYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDF 240
TYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDF
Sbjct: 181 TYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDF 240
Query: 241 DGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQ 300
DGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQ
Sbjct: 241 DGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQ 300
Query: 301 QEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVV 360
QEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVV
Sbjct: 301 QEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVV 360
Query: 361 PPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKS 420
PPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKS
Sbjct: 361 PPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKS 420
Query: 421 SWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGT 480
SWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGT
Sbjct: 421 SWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGT 480
Query: 481 YTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKS 540
YTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKS
Sbjct: 481 YTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKS 540
Query: 541 PASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAA 600
PASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAA
Sbjct: 541 PASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAA 600
Query: 601 TPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPT 660
TPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPT
Sbjct: 601 TPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPT 660
Query: 661 EELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCS 720
EELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCS
Sbjct: 661 EELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCS 720
Query: 721 GSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITA 780
GSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITA
Sbjct: 721 GSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITA 780
Query: 781 PEGSFASADALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKL 840
PEGSFASADALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKL
Sbjct: 781 PEGSFASADALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKL 840
Query: 841 ARQIALASRSHQDAKREAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIA 900
ARQIALASRSHQDAKREAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIA
Sbjct: 841 ARQIALASRSHQDAKREAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIA 900
Query: 901 RAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQL 960
RAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQL
Sbjct: 901 RAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQL 960
Query: 961 VLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRY 1020
VLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRY
Sbjct: 961 VLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRY 1020
Query: 1021 QALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEEL 1080
QALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEEL
Sbjct: 1021 QALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEEL 1080
Query: 1081 TKICDELIAKMGKS 1094
TKICDELIAKMGKS
Sbjct: 1081 TKICDELIAKMGKS 1094
>gi|150418009 transforming, acidic coiled-coil containing protein 2
isoform a [Homo sapiens]
Length = 2948
Score = 2048 bits (5307), Expect = 0.0
Identities = 1054/1131 (93%), Positives = 1057/1131 (93%), Gaps = 54/1131 (4%)
Query: 18 TPRSAQPPGNSQNIKRKQQDTPGSPDH---------RDASSSPVADDIIQPAAPADLESP 68
T R + PG S ++D P D SSPVADDIIQPAAPADLESP
Sbjct: 1818 TDRESPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPADLESP 1877
Query: 69 TLAASSYHGDVVGQVSTDLIAQ-------------------------------------- 90
TLAASSYHGDVVGQVSTDLIAQ
Sbjct: 1878 TLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRVEASTPSCP 1937
Query: 91 -------RSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV 143
RSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV
Sbjct: 1938 DPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV 1997
Query: 144 PVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRAS 203
PVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRAS
Sbjct: 1998 PVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRAS 2057
Query: 204 DAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGS 263
DAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGS
Sbjct: 2058 DAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGS 2117
Query: 264 SSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTES 323
SSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTES
Sbjct: 2118 SSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTES 2177
Query: 324 AKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLT 383
AKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLT
Sbjct: 2178 AKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLT 2237
Query: 384 TAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKM 443
TAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKM
Sbjct: 2238 TAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKM 2297
Query: 444 PLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQ 503
PLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQ
Sbjct: 2298 PLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQ 2357
Query: 504 ESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNK 563
ESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNK
Sbjct: 2358 ESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNK 2417
Query: 564 PAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVT 623
PAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVT
Sbjct: 2418 PAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVT 2477
Query: 624 NQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQ 683
NQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQ
Sbjct: 2478 NQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQ 2537
Query: 684 DDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPR 743
DDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPR
Sbjct: 2538 DDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPR 2597
Query: 744 GLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCG 803
GLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCG
Sbjct: 2598 GLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCG 2657
Query: 804 ALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTD 863
ALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTD
Sbjct: 2658 ALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTD 2717
Query: 864 VSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRR 923
VSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRR
Sbjct: 2718 VSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRR 2777
Query: 924 EVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFR 983
EVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFR
Sbjct: 2778 EVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFR 2837
Query: 984 RYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRG 1043
RYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRG
Sbjct: 2838 RYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRG 2897
Query: 1044 KAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 1094
KAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS
Sbjct: 2898 KAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 2948
Score = 117 bits (293), Expect = 6e-26
Identities = 179/679 (26%), Positives = 244/679 (35%), Gaps = 116/679 (17%)
Query: 1 MGNENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPA 60
MGNENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASS
Sbjct: 1 MGNENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSI---------- 50
Query: 61 APADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAP------ 114
VG ++ S+ + +PE T P K P
Sbjct: 51 -----------------GSVGLGGFCTASESSASLDPCLVSPEVTEPRKDPQGARGPEGS 93
Query: 115 --PPPPPEVIPEPEVSTQP----PPEEPGCGSETVPVP-DGPRSDSVEGSPFRPPSHSFS 167
P PPP E S+ P PPE GC + P DGP++ S P +
Sbjct: 94 LLPSPPPSQEREHPSSSMPFAECPPE--GCLASPAAAPEDGPQTQSPRREPAPNAPGDIA 151
Query: 168 AVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKS 227
A F ++ SS Y + + + +P+ K+ + +S P+
Sbjct: 152 AAFPAERD--SSTPYQ---EIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLR 206
Query: 228 TLSRSLSLQASDFDGASSSGNPEA---------------VALAPDAYSTGSSSASSTLKR 272
++ D G S EA V + P+A + S+
Sbjct: 207 EPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVL 266
Query: 273 TKKPRPPSLKKKQTTKKPTETPPVKET-QQEPDEESLVPSGENLAS---ETKTESAKTEG 328
K P P Q P +E Q E + L E L + A E
Sbjct: 267 EKSPLKPMAPIPQ---DPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEA 323
Query: 329 PSPALLEETPLEP--AVGPKAACPLDSESAEGVVPPASGGGR-------VQNSPPVG-RK 378
A +E+ +P A P A P S +VP A G G+ VQ P G R
Sbjct: 324 EVNAASQESCQQPVGAYLPHAELPWGLPS-PALVPEAGGSGKEALDTIDVQGHPQTGMRG 382
Query: 379 TLP---------------LTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSE-DKSSW 422
T P L +PE +TP++ S A + ++ E SS
Sbjct: 383 TKPNQVVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSR 442
Query: 423 DNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAE-PNDIPIAKGTY 481
++ + P K V L +++ L + P P E P P +G +
Sbjct: 443 ESVSKAGMPVSADAAKEVVDAGL--VGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEH 500
Query: 482 -----TFDIDKWDDPNFNPFSSTSKMQES------PKLPQQSYNFDPDTCD-ESVDPFKT 529
+ ++ P P + ++Q PK P +S P D V T
Sbjct: 501 LNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDST 560
Query: 530 SSKTPSSPSKSPASFEIPASAMEANGV--DGDGLNKPAKKKKTPLKTDTFRVKKSPKRSP 587
S S+SP + P EA GD N + + V K P
Sbjct: 561 SPAVAKEGSRSPG--DSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKP 618
Query: 588 LSDPPSQDPTPAATPETPP 606
SD S+D P++ PP
Sbjct: 619 SSDAESRD-HPSSHSAQPP 636
>gi|11119414 transforming, acidic coiled-coil containing protein 2
isoform d [Homo sapiens]
Length = 1026
Score = 1986 bits (5146), Expect = 0.0
Identities = 1003/1003 (100%), Positives = 1003/1003 (100%)
Query: 92 SSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRS 151
SSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRS
Sbjct: 24 SSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRS 83
Query: 152 DSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGK 211
DSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGK
Sbjct: 84 DSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGK 143
Query: 212 VNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLK 271
VNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLK
Sbjct: 144 VNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLK 203
Query: 272 RTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSP 331
RTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSP
Sbjct: 204 RTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSP 263
Query: 332 ALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEV 391
ALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEV
Sbjct: 264 ALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEV 323
Query: 392 TPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMK 451
TPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMK
Sbjct: 324 TPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMK 383
Query: 452 KTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQ 511
KTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQ
Sbjct: 384 KTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQ 443
Query: 512 SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTP 571
SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTP
Sbjct: 444 SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTP 503
Query: 572 LKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMT 631
LKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMT
Sbjct: 504 LKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMT 563
Query: 632 VDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQ 691
VDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQ
Sbjct: 564 VDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQ 623
Query: 692 ALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQES 751
ALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQES
Sbjct: 624 ALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQES 683
Query: 752 HLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGALDYLEPD 811
HLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGALDYLEPD
Sbjct: 684 HLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGALDYLEPD 743
Query: 812 LAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKTAL 871
LAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKTAL
Sbjct: 744 LAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKTAL 803
Query: 872 YSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKI 931
YSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKI
Sbjct: 804 YSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKI 863
Query: 932 VAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEV 991
VAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEV
Sbjct: 864 VAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEV 923
Query: 992 LEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAA 1051
LEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAA
Sbjct: 924 LEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAA 983
Query: 1052 HQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 1094
HQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS
Sbjct: 984 HQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 1026
Score = 36.6 bits (83), Expect = 0.13
Identities = 61/264 (23%), Positives = 87/264 (32%), Gaps = 45/264 (17%)
Query: 424 NQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAK----- 478
+Q P P + + M + +TPE A P P P IP +
Sbjct: 4 SQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQP 63
Query: 479 -------GTYTF---DIDKWDDPNFNPFSSTSKM------QESPKLPQQSYNFDPDTCDE 522
G+ T D + D +PF S ++ P +YN D D E
Sbjct: 64 PPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNI-E 122
Query: 523 SVDPFKT------------------SSKTPSSP-SKSPASFEIPASAMEANGVDGDGLNK 563
VD F+T T S P SKS S + A + +G G +
Sbjct: 123 LVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPE 182
Query: 564 PAKKKKTPLKTDTFRVKKSPKRSPLSDPPS--QDPTPAATPETPPVISAVVHATDEEKLA 621
T + + KR+ PPS + T ETPPV DEE L
Sbjct: 183 AVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPV-KETQQEPDEESLV 241
Query: 622 VTNQKWTCMTVDLEADKQDYPQPS 645
+ + T E+ K + P P+
Sbjct: 242 PSGENLASET-KTESAKTEGPSPA 264
>gi|45827753 transforming, acidic coiled-coil containing protein 2
isoform c [Homo sapiens]
Length = 996
Score = 1917 bits (4965), Expect = 0.0
Identities = 973/1003 (97%), Positives = 973/1003 (97%), Gaps = 30/1003 (2%)
Query: 92 SSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRS 151
SSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRS
Sbjct: 24 SSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRS 83
Query: 152 DSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGK 211
DSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGK
Sbjct: 84 DSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGK 143
Query: 212 VNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLK 271
VNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLK
Sbjct: 144 VNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLK 203
Query: 272 RTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSP 331
RTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSP
Sbjct: 204 RTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSP 263
Query: 332 ALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEV 391
ALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEV
Sbjct: 264 ALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEV 323
Query: 392 TPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMK 451
TPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMK
Sbjct: 324 TPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMK 383
Query: 452 KTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQ 511
KTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQ
Sbjct: 384 KTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQ 443
Query: 512 SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTP 571
SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTP
Sbjct: 444 SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTP 503
Query: 572 LKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMT 631
LKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMT
Sbjct: 504 LKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMT 563
Query: 632 VDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQ 691
VDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQ
Sbjct: 564 VDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQ 623
Query: 692 ALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQES 751
ALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQES
Sbjct: 624 ALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQES 683
Query: 752 HLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGALDYLEPD 811
HLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGALDYLEPD
Sbjct: 684 HLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGALDYLEPD 743
Query: 812 LAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKTAL 871
LAEKNPPLFAQKLQ REAAHPTDVSISKTAL
Sbjct: 744 LAEKNPPLFAQKLQ------------------------------REAAHPTDVSISKTAL 773
Query: 872 YSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKI 931
YSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKI
Sbjct: 774 YSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKI 833
Query: 932 VAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEV 991
VAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEV
Sbjct: 834 VAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEV 893
Query: 992 LEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAA 1051
LEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAA
Sbjct: 894 LEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAA 953
Query: 1052 HQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 1094
HQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS
Sbjct: 954 HQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 996
Score = 36.6 bits (83), Expect = 0.13
Identities = 61/264 (23%), Positives = 87/264 (32%), Gaps = 45/264 (17%)
Query: 424 NQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAK----- 478
+Q P P + + M + +TPE A P P P IP +
Sbjct: 4 SQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQP 63
Query: 479 -------GTYTF---DIDKWDDPNFNPFSSTSKM------QESPKLPQQSYNFDPDTCDE 522
G+ T D + D +PF S ++ P +YN D D E
Sbjct: 64 PPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNI-E 122
Query: 523 SVDPFKT------------------SSKTPSSP-SKSPASFEIPASAMEANGVDGDGLNK 563
VD F+T T S P SKS S + A + +G G +
Sbjct: 123 LVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPE 182
Query: 564 PAKKKKTPLKTDTFRVKKSPKRSPLSDPPS--QDPTPAATPETPPVISAVVHATDEEKLA 621
T + + KR+ PPS + T ETPPV DEE L
Sbjct: 183 AVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPV-KETQQEPDEESLV 241
Query: 622 VTNQKWTCMTVDLEADKQDYPQPS 645
+ + T E+ K + P P+
Sbjct: 242 PSGENLASET-KTESAKTEGPSPA 264
>gi|170763517 transforming, acidic coiled-coil containing protein 1
isoform 1 [Homo sapiens]
Length = 805
Score = 306 bits (785), Expect = 5e-83
Identities = 279/891 (31%), Positives = 410/891 (46%), Gaps = 146/891 (16%)
Query: 237 ASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPT---ET 293
A + + G+PE + S SS S T + P + + P+
Sbjct: 27 AGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGNFETPEAETPIRSPFKESCDPSLGLAG 86
Query: 294 PPVKETQ-QEPDEESLVPSGENLASETKTESAKTEGPSPAL-------LEETPLEPAVGP 345
P K + QE DE+ + E +S+T ++ ++ E P A+ E P
Sbjct: 87 PGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAIDSHSVKNFREEPEHDFSKI 146
Query: 346 KAACPLDSESAEGVVPPASGGGRVQNS--PPVGRKTLPLTTAPEAGEVTPSDSGGQEDSP 403
P E+ + A G + + V K LP + P D+ E
Sbjct: 147 SIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSS---------PPDALQDEAMT 197
Query: 404 AKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPAS 463
+ V LE D + ++ E P + +KP +PLR+ K + +T A+
Sbjct: 198 EGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKP-KPVPLRK---KAIGGEFSDTNAA 253
Query: 464 PPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQSYNFDPDTCDE 522
+P + K +Y F ++ D+ N +P ++ Q+SP L + DT D
Sbjct: 254 VEGTP-------LPKASYHFSPEELDE-NTSPLLGDARFQKSPPDLKETPGTLSSDTNDS 305
Query: 523 SVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKS 582
V+ ++ SSP K F +EA L + TP K + KS
Sbjct: 306 GVE---LGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTP-KIQKDGISKS 361
Query: 583 P----------KRSPLSDPPSQ-DPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMT 631
+ PLS S+ DP+ +P P S H+ + ++++
Sbjct: 362 AGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGS---HSVLQNSPPLSSEGSYHFD 418
Query: 632 VDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQ 691
D + D +P+ T + + F SPT G+ + + ++PKK
Sbjct: 419 PDNFDESMDPFKPT---TTLTSSDFCSPT-----------------GNHVNEILESPKKA 458
Query: 692 ALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAP--NQ 749
L+ + C E ++ ++++ V ++ N+
Sbjct: 459 KSRLI-------------------TSGCKVKKHETQSLALDACSRDEGAVISQISDISNR 499
Query: 750 ESHLQVPEKSS-----QKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGA 804
+ H EK + QK A G P E +E F ++ +S + H A
Sbjct: 500 DGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEY------FECSNVPVSTINH------A 547
Query: 805 LDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDV 864
E + ++ QK++E+ + +E+ +A V
Sbjct: 548 FSSSEAGIEKET----CQKMEEDGSTVLGLLES--------------------SAEKAPV 583
Query: 865 SISKTALYSRIGTAEVEKPA-GLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRR 923
S+S E P G+ + D + L + R EIITKE E +EWK KYEE+R+
Sbjct: 584 SVSCGG----------ESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQ 633
Query: 924 EVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFR 983
EV+EMRKIVAEYEKTIAQMIEDEQR S ++ QQL +EKEQALADLNSVE+SL+DLFR
Sbjct: 634 EVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFR 693
Query: 984 RYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRG 1043
RYE +K VLEGF+KNEE LK+CAQ+YL+RVK+EEQRYQALK+HAEEKLD+AN EIAQVR
Sbjct: 694 RYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRT 753
Query: 1044 KAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 1094
KA+ E AA A LRKEQ++V++LER L+QKN+EIEELTKICDELIAK+GK+
Sbjct: 754 KAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKT 804
Score = 121 bits (304), Expect = 3e-27
Identities = 165/635 (25%), Positives = 259/635 (40%), Gaps = 120/635 (18%)
Query: 92 SSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEE---------PGCGSET 142
SSDSE FETPE+ TP+++P P + P +Q E C S+T
Sbjct: 54 SSDSEGNFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKT 113
Query: 143 VPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRA 202
P E SHS +E + DF I +V F
Sbjct: 114 CSKP-----SENEVPQQAIDSHSVKNFREEPEH---------DFSKISIVRPFSI---ET 156
Query: 203 SDAKNQEGKVNTRRKSTDSVPISKSTLSRSL--SLQASDFDGASSSGNPEAVALAP-DAY 259
D+ + + T+ +S L S +LQ S EA A A A
Sbjct: 157 KDSTDISAVLGTKAAHGCVTAVSGKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAG 216
Query: 260 STGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASET 319
++ S + +KP+P L+KK + E
Sbjct: 217 NSCPELVPSRRSKLRKPKPVPLRKKA-----------------------------IGGEF 247
Query: 320 KTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKT 379
+A EG TPL PKA+ E + P G R Q SPP ++T
Sbjct: 248 SDTNAAVEG--------TPL-----PKASYHFSPEELDENTSPLLGDARFQKSPPDLKET 294
Query: 380 LPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKP 439
P T + + +DSG + ++ ++LEFD++ED + + ++ P +K+G+K
Sbjct: 295 -PGTLSSDT-----NDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALP---RKLGRKL 345
Query: 440 VAKMPLRRPKMKKTPEKLDNTPASPPRSPAEP--NDIPIAKGTYTFDIDKWDDPNFNPFS 497
+ + PK++K + ++ P +P D P+++ + D +W+ P+FNPF
Sbjct: 346 GSTL---TPKIQKD----GISKSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFG 398
Query: 498 STSKMQESPKLPQQ-SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGV 556
S S +Q SP L + SY+FDPD DES+DPFK ++ SS SP +
Sbjct: 399 SHSVLQNSPPLSSEGSYHFDPDNFDESMDPFKPTTTLTSSDFCSPTGNHV---------- 448
Query: 557 DGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATD 616
+ L P KK K+ L T +VKK +S D S+D A + + + HATD
Sbjct: 449 -NEILESP-KKAKSRLITSGCKVKKHETQSLALDACSRD-EGAVISQISDISNRDGHATD 505
Query: 617 EEKLAVTN--QKWTCMTVDLEADKQ-DYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEY 673
EEKLA T+ QK V E ++ +Y + S++ FSS ++ +
Sbjct: 506 EEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKET---CQK 562
Query: 674 MEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSS 708
ME+ GS++ L L+ +++++PV S
Sbjct: 563 MEEDGSTV-----------LGLLESSAEKAPVSVS 586
Score = 42.7 bits (99), Expect = 0.002
Identities = 46/167 (27%), Positives = 73/167 (43%), Gaps = 14/167 (8%)
Query: 41 SPDHRDASSSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFE 100
SP+ D ++SP+ D +P DL+ SS D ++ + RSS + F+
Sbjct: 267 SPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDSGVELGEE---SRSSPLKLEFD 323
Query: 101 TPESTTPVKAPPAPPPPPPEVIPE---PEVSTQPPPEEPGCGSETVPVP-DGPRSD-SVE 155
E T ++A A P + P++ + G T PV DGP S S +
Sbjct: 324 FTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPTDPVARDGPLSQTSSK 383
Query: 156 GSPFRPPSHSFS-----AVFDEDKPIASSGTYNLDFDNI-ELVDTFQ 196
P + S SF+ +V P++S G+Y+ D DN E +D F+
Sbjct: 384 PDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDPFK 430
>gi|226246618 transforming, acidic coiled-coil containing protein 1
isoform 3 [Homo sapiens]
Length = 610
Score = 300 bits (769), Expect = 4e-81
Identities = 237/676 (35%), Positives = 336/676 (49%), Gaps = 115/676 (17%)
Query: 439 PVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSS 498
P + LR+PK +K S + E +P K +Y F ++ D+ N +P
Sbjct: 29 PSRRSKLRKPKPVPLRKKAIGGEFSDTNAAVEGTPLP--KASYHFSPEELDE-NTSPLLG 85
Query: 499 TSKMQESPK-LPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVD 557
++ Q+SP L + DT D V+ ++ SSP K F +EA
Sbjct: 86 DARFQKSPPDLKETPGTLSSDTNDSGVE---LGEESRSSPLKLEFDFTEDTGNIEARKAL 142
Query: 558 GDGLNKPAKKKKTPLKTDTFRVKKSP----------KRSPLSDPPSQ-DPTPAATPETPP 606
L + TP K + KS + PLS S+ DP+ +P P
Sbjct: 143 PRKLGRKLGSTLTP-KIQKDGISKSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNP 201
Query: 607 VISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYR 666
S H+ + ++++ D + D +P+ T + + F SPT
Sbjct: 202 FGS---HSVLQNSPPLSSEGSYHFDPDNFDESMDPFKPT---TTLTSSDFCSPT------ 249
Query: 667 NSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEE 726
G+ + + ++PKK L+ + C E
Sbjct: 250 -----------GNHVNEILESPKKAKSRLI-------------------TSGCKVKKHET 279
Query: 727 TEALVNTAAKNQHPVPRGLAP--NQESHLQVPEKSS-----QKELEAMGLGTPSEAIEIT 779
++ ++++ V ++ N++ H EK + QK A G P E +E
Sbjct: 280 QSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEY- 338
Query: 780 APEGSFASADALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALK 839
F ++ +S + H A E + ++ QK++E+ + +E+
Sbjct: 339 -----FECSNVPVSTINH------AFSSSEAGIEKET----CQKMEEDGSTVLGLLES-- 381
Query: 840 LARQIALASRSHQDAKREAAHPTDVSISKTALYSRIGTAEVEKPA-GLLFQQPDLDSALQ 898
+A VS+S E P G+ + D + L
Sbjct: 382 ------------------SAEKAPVSVSCGG----------ESPLDGICLSESDKTAVLT 413
Query: 899 IARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQ 958
+ R EIITKE E +EWK KYEE+R+EV+EMRKIVAEYEKTIAQMIEDEQR S ++ Q
Sbjct: 414 LIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQ 473
Query: 959 QLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQ 1018
QL +EKEQALADLNSVE+SL+DLFRRYE +K VLEGF+KNEE LK+CAQ+YL+RVK+EEQ
Sbjct: 474 QLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQ 533
Query: 1019 RYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIE 1078
RYQALK+HAEEKLD+AN EIAQVR KA+ E AA A LRKEQ++V++LER L+QKN+EIE
Sbjct: 534 RYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIE 593
Query: 1079 ELTKICDELIAKMGKS 1094
ELTKICDELIAK+GK+
Sbjct: 594 ELTKICDELIAKLGKT 609
Score = 112 bits (279), Expect = 2e-24
Identities = 112/383 (29%), Positives = 183/383 (47%), Gaps = 54/383 (14%)
Query: 332 ALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEV 391
A +E TPL PKA+ E + P G R Q SPP ++T P T + +
Sbjct: 57 AAVEGTPL-----PKASYHFSPEELDENTSPLLGDARFQKSPPDLKET-PGTLSSDT--- 107
Query: 392 TPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMK 451
+DSG + ++ ++LEFD++ED + + ++ P +K+G+K + + PK++
Sbjct: 108 --NDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALP---RKLGRKLGSTLT---PKIQ 159
Query: 452 KTPEKLDNTPASPPRSPAEP--NDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLP 509
K + ++ P +P D P+++ + D +W+ P+FNPF S S +Q SP L
Sbjct: 160 KD----GISKSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLS 215
Query: 510 QQ-SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKK 568
+ SY+FDPD DES+DPFK ++ SS SP + + L P KK
Sbjct: 216 SEGSYHFDPDNFDESMDPFKPTTTLTSSDFCSPTGNHV-----------NEILESP-KKA 263
Query: 569 KTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTN--QK 626
K+ L T +VKK +S D S+D A + + + HATDEEKLA T+ QK
Sbjct: 264 KSRLITSGCKVKKHETQSLALDACSRD-EGAVISQISDISNRDGHATDEEKLASTSCGQK 322
Query: 627 WTCMTVDLEADKQ-DYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDD 685
V E ++ +Y + S++ FSS ++ + ME+ GS++
Sbjct: 323 SAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKET---CQKMEEDGSTV---- 375
Query: 686 DAPKKQALYLMFDTSQESPVKSS 708
L L+ +++++PV S
Sbjct: 376 -------LGLLESSAEKAPVSVS 391
Score = 42.7 bits (99), Expect = 0.002
Identities = 46/167 (27%), Positives = 73/167 (43%), Gaps = 14/167 (8%)
Query: 41 SPDHRDASSSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFE 100
SP+ D ++SP+ D +P DL+ SS D ++ + RSS + F+
Sbjct: 72 SPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDSGVELGEE---SRSSPLKLEFD 128
Query: 101 TPESTTPVKAPPAPPPPPPEVIPE---PEVSTQPPPEEPGCGSETVPVP-DGPRSD-SVE 155
E T ++A A P + P++ + G T PV DGP S S +
Sbjct: 129 FTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPTDPVARDGPLSQTSSK 188
Query: 156 GSPFRPPSHSFS-----AVFDEDKPIASSGTYNLDFDNI-ELVDTFQ 196
P + S SF+ +V P++S G+Y+ D DN E +D F+
Sbjct: 189 PDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDPFK 235
>gi|170763519 transforming, acidic coiled-coil containing protein 1
isoform 2 [Homo sapiens]
Length = 395
Score = 298 bits (762), Expect = 2e-80
Identities = 149/210 (70%), Positives = 179/210 (85%)
Query: 885 GLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIE 944
G+ + D + L + R EIITKE E +EWK KYEE+R+EV+EMRKIVAEYEKTIAQMIE
Sbjct: 185 GICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIE 244
Query: 945 DEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKR 1004
DEQR S ++ QQL +EKEQALADLNSVE+SL+DLFRRYE +K VLEGF+KNEE LK+
Sbjct: 245 DEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKK 304
Query: 1005 CAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVD 1064
CAQ+YL+RVK+EEQRYQALK+HAEEKLD+AN EIAQVR KA+ E AA A LRKEQ++V+
Sbjct: 305 CAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVE 364
Query: 1065 ALERTLEQKNKEIEELTKICDELIAKMGKS 1094
+LER L+QKN+EIEELTKICDELIAK+GK+
Sbjct: 365 SLERALQQKNQEIEELTKICDELIAKLGKT 394
>gi|5454102 transforming, acidic coiled-coil containing protein 3
[Homo sapiens]
Length = 838
Score = 211 bits (537), Expect = 3e-54
Identities = 107/208 (51%), Positives = 151/208 (72%), Gaps = 7/208 (3%)
Query: 886 LLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIED 945
L + Q DLD+ ++ + E E + + EE + +E+ KI+ +E+ + Q +E+
Sbjct: 637 LQYSQKDLDAVVKAT-------QEENRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEE 689
Query: 946 EQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRC 1005
Q++K +S +Q+++ EK+Q DLNS+EKS +DLF+R+EK KEV+EG+RKNEE LK+C
Sbjct: 690 VQKQKELSKAEIQKVLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEVIEGYRKNEESLKKC 749
Query: 1006 AQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDA 1065
++YL+R+ +E QRYQALK HAEEKL AN EIAQVR KAQ E A QASLRKEQ+R+ +
Sbjct: 750 VEDYLARITQEGQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQS 809
Query: 1066 LERTLEQKNKEIEELTKICDELIAKMGK 1093
LE+T+EQK KE EELT+ICD+LI+KM K
Sbjct: 810 LEKTVEQKTKENEELTRICDDLISKMEK 837
Score = 102 bits (254), Expect = 2e-21
Identities = 192/868 (22%), Positives = 329/868 (37%), Gaps = 177/868 (20%)
Query: 200 PRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAY 259
P + +NQ+ K+T + L AS G+ SS ALA
Sbjct: 95 PVWTQKENQQLIKEVDAKTTHGILQKPVEADTDLLGDASPAFGSGSSSESGPGALADLDC 154
Query: 260 STGSSSASSTLKRTKKPRPPSLKKKQTTKKPTET-------PPVKETQQEP-----DEES 307
S+ S S S+ + P S +Q ++ + P ET ++P ++
Sbjct: 155 SSSSQSPGSSENQMVSPGKVSGSPEQAVEENLSSYSLDRRVTPASETLEDPCRTESQHKA 214
Query: 308 LVPSGENLASETKTESAKTEGP------SPALLEETPLEPAVGPKAAC---PLDSESAEG 358
P G + +T E +PA + +P P PK AC PL E
Sbjct: 215 ETPHGAEEECKAETPHGAEEECRHGGVCAPAAVATSP--PGAIPKEACGGAPLQGLPGEA 272
Query: 359 VVPPASGGGRVQNSPPVGRKTL-------PLTTAP-------EAGEVTPSD--SGGQEDS 402
+ PA G V P G +TL P +TAP A ++P + + GQ S
Sbjct: 273 LGCPAGVGTPV---PADGTQTLTCAHTSAPESTAPTNHLVAGRAMTLSPQEEVAAGQMAS 329
Query: 403 PAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRP--KMKKTPEKLDNT 460
++ V+LEFD S+ +S + PP +++G++ K PLR+ + +K P++++
Sbjct: 330 SSRSGPVKLEFDVSDGATS-----KRAPPPRRLGERSGLKPPLRKAAVRQQKAPQEVEED 384
Query: 461 PASPPRSPA-EPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDT 519
RS A E +P ++G+Y D DK DDPNF PF +K
Sbjct: 385 DG---RSGAGEDPPMPASRGSYHLDWDKMDDPNFIPFGGDTK----------------SG 425
Query: 520 CDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRV 579
C E+ P ++P + PA+ ++ A PA ++ P
Sbjct: 426 CSEAQPP-----ESPETRLGQPAAEQLHAG--------------PATEEPGPCL------ 460
Query: 580 KKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLE-ADK 638
SQ A+ +TP V A T E K N T + ++
Sbjct: 461 -------------SQQLHSASAEDTPVVQLAAETPTAESKERALNSASTSLPTSCPGSEP 507
Query: 639 QDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFD 698
Q + + E F P E L E++Y+E+ G+S + A +KQ+LYL FD
Sbjct: 508 VPTHQQGQPALELKEESFRDPAEVLG--TGAEVDYLEQFGTS-SFKESALRKQSLYLKFD 564
Query: 699 -TSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQVPE 757
++SP + PV S + N+ P R P
Sbjct: 565 PLLRDSPGRPVPVATETS----------------SMHGANETPSGR------------PR 596
Query: 758 KSSQKELEAMG---LGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGALDYLEPDLAE 814
++ E + +G + P + AP G P+S +D L+ ++
Sbjct: 597 EAKLVEFDFLGALDIPVPGPPPGVPAPGGP-------------PLSTGPIVDLLQ--YSQ 641
Query: 815 KNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKTALYSR 874
K+ + QEE R E L + + L D E + + K
Sbjct: 642 KDLDAVVKATQEENRELRSRCEELH-GKNLELG--KIMDRFEEVVYQAMEEVQK---QKE 695
Query: 875 IGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAE 934
+ AE++K +L ++ L + L + + K+ E R+ ++K V +
Sbjct: 696 LSKAEIQK---VLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEVIEGYRKNEESLKKCVED 752
Query: 935 YEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQ-------ALADLNSVEKSLADLFRRYEK 987
Y +A++ ++ QR +++ ++L L E+ A A+ +++ SL R +
Sbjct: 753 Y---LARITQEGQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQS 809
Query: 988 MKEVLEGFRKNEEVLKRCAQEYLSRVKK 1015
+++ +E K E L R + +S+++K
Sbjct: 810 LEKTVEQKTKENEELTRICDDLISKMEK 837
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 83.2 bits (204), Expect = 1e-15
Identities = 151/646 (23%), Positives = 211/646 (32%), Gaps = 126/646 (19%)
Query: 16 AQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQ---PAAPADLESPTLAA 72
A TP +A PP + P +P + A + P A PA P+ +PT A
Sbjct: 939 APTPPAATPPS--------PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA 990
Query: 73 SSYHGDVVGQVSTDLIAQRSSDSEEAFETPESTTP---------------VKAPPAPPPP 117
++ G ++ S + TP + TP PPA PP
Sbjct: 991 ATPPSPKGGP---------ATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPP 1041
Query: 118 PPEVIPEPEVSTQPPPEEPGCGSETVPVPDG-PRSDSVEGSPFRPPSHSFSAVFDEDKPI 176
P+ P +T P P + T+P P G P + S++G+P P + S P
Sbjct: 1042 SPKGSP---AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPS 1098
Query: 177 ASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQ 236
+ P A+ + G K + P + + L
Sbjct: 1099 PKGAP----------------MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG-GLA 1141
Query: 237 ASDFDGASSSGNPEAVALAPDA-YSTGSSSASSTLKRTKKPRP------PSLKKKQTTKK 289
GA ++ P A +P +T + T P P PS K TT
Sbjct: 1142 TPPPKGAPTT--PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTT-- 1197
Query: 290 PTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGP--SPALLEETPLEPAVGPKA 347
P TPP + P+ + T P +P TP P GP
Sbjct: 1198 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPAT 1257
Query: 348 ACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVT-PSDSGGQEDSPAKG 406
P + + PP+ GG T P AP VT PS GG SP KG
Sbjct: 1258 PPPKGAPTPPAATPPSLKGGLA---------TPPHKGAPNPAVVTPPSPKGGPATSPPKG 1308
Query: 407 LSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPR 466
PT P K P K P TP SP
Sbjct: 1309 -----------------------APTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345
Query: 467 SPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDP 526
+P P P +KG T K + P P ++T + P + S P DP
Sbjct: 1346 TPTLPATTPSSKGGPTTPSSK-EGP--TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402
Query: 527 FKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKK----- 581
+ + P SP K+PA+ V +G P+K TP +KK
Sbjct: 1403 -TSPAVIPLSPKKAPAT-----------PVTREGAATPSKGDLTPPAVTPVSLKKAPATS 1450
Query: 582 SPKRSPLSDPPSQDPT-PAAT---PETPPVISAVVHATDEEKLAVT 623
+PK P + DPT PA T P+ PP V ++ +K T
Sbjct: 1451 APKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPAT 1496
Score = 72.4 bits (176), Expect = 2e-12
Identities = 156/728 (21%), Positives = 250/728 (34%), Gaps = 89/728 (12%)
Query: 38 TPGSPDHRDASSSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQR--SSDS 95
TP SP A+ P A P L+ LA + G V T + ++
Sbjct: 1247 TPPSPKGGPATPPPKGAPTPPAATPPSLKGG-LATPPHKGAPNPAVVTPPSPKGGPATSP 1305
Query: 96 EEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPE-EPGCGSETVPVPDGPRSDSV 154
+ TP + TP +P PPP+ P P T P P+ P + T GP + S
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS 1365
Query: 155 EGSPFRP---PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAK--NQE 209
+ P P PSH P + D L P+ + A +E
Sbjct: 1366 KEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTS--PAVIPLSPKKAPATPVTRE 1423
Query: 210 GKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGA--SSSGNPEAVALAPDA-------YS 260
G + ++ +L ++ + A A SS G+P A+ P +
Sbjct: 1424 GAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ 1483
Query: 261 TGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEP----------------- 303
+SS+ T P P E P ++++P
Sbjct: 1484 VATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLA 1543
Query: 304 DEESLVPSGENLASETKTESAKT--EGPSPALLEETPLEPAVGPKAACPLDSESAEGVVP 361
+E+L+P + S KT + T E P+ +E PAV P S E ++P
Sbjct: 1544 PKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK-ELLIP 1602
Query: 362 PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSG----------GQEDSPAKGLSVRL 411
PA + +P T P +PE G TP+ G +DSP SV
Sbjct: 1603 PAVTSPSPKEAPTPPAVTPP---SPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTC 1659
Query: 412 EFDYSEDKSSWD-NQQENPPPTKKIGKKPVAK-MPLRRPKMKKTPEKLDNTPASPPRSPA 469
+ + ++S ++ P K++ P + P+ +K P+ ++ SPP P
Sbjct: 1660 KMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICP- 1718
Query: 470 EPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKT 529
+P+ +KG P S+ + +P LP Q D + D
Sbjct: 1719 DPSAKNGSKG---------------PLSTVA---PAPLLPVQK---DSSKTAKGKDA-SH 1756
Query: 530 SSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLS 589
S K P +P +S AS + A+A E L KP + + + +P P
Sbjct: 1757 SPKGPLAPPESKASTPLTAAAFE------KVLPKPESASVSAAPSPPVSLPLAPSPVPTL 1810
Query: 590 DPPSQ--DPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDL 647
P Q +P E+P + A ++E L + + V ++ + P P
Sbjct: 1811 PPKQQFLPSSPGLVLESPS--KPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSA 1868
Query: 648 STFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDD-DAPKKQALYLMFDTSQESPVK 706
V P + + + E + E + QD A +QA E PV
Sbjct: 1869 GIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVS 1928
Query: 707 SSPVRMSE 714
+ SE
Sbjct: 1929 KAKQSRSE 1936
Score = 63.5 bits (153), Expect = 1e-09
Identities = 136/607 (22%), Positives = 183/607 (30%), Gaps = 76/607 (12%)
Query: 36 QDTPGSPDHRDASSSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQRSS-- 93
++ P +P ++ + +P+A ++ P P + SP+L + G G D I+ S+
Sbjct: 706 ENCPVAPSPQN-TCAPLATLVLAPEIPKSVPSPSLPPA---GTPPGTKKVDGISHTSALA 761
Query: 94 ---DSEEAFETPESTTPVKAPP-------APPPPPPEVIPEPEVSTQPPPEEPGCGSETV 143
S + T +S A A P P V P+ T+ PP + G
Sbjct: 762 PVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQ--TKRPPTKKGSAGPDT 819
Query: 144 PVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRAS 203
P+ + S + F P +S S +D P + L P+
Sbjct: 820 PIGNLSSPVSPVEASFLP-ENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGV 878
Query: 204 DAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGS 263
+E T S ++P K + QA SSS P+ P +
Sbjct: 879 TLPPKE----TPTPSVVNLPFPKEGPATPAPKQAPALSMTSSS--PKKARATPAPKGIPA 932
Query: 264 SSASSTLKRTKKPRPPSLKKKQTTKKPTETP-PVKETQQEPDEESLVPSGENLASETKTE 322
S + PPS K T P P P T P PS +
Sbjct: 933 SPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKG-------- 984
Query: 323 SAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPL 382
P+P TP P GP P + + V PP+ G P G T P
Sbjct: 985 -----APTPPAA--TPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037
Query: 383 TTAPE-----------------AGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQ 425
T P PS GG KG K
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097
Query: 426 QENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDI 485
P P K L P K P TPA+ P SP P KG T
Sbjct: 1098 SPKGAPMPPAATPPSPKGGLATPPHKGAP----TTPAATPPSPKGGLATPPPKGAPTTPA 1153
Query: 486 DKWDDPNFNPFSSTSK-MQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSP-----SK 539
P + K +P S T P T + TP SP +
Sbjct: 1154 ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP-TTPAATPPSPKGGLATP 1212
Query: 540 SPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPA 599
SP +A + G P TP T SPK P + PP PTP
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT-----PPSPKGGPATPPPKGAPTPP 1267
Query: 600 ATPETPP 606
A TPP
Sbjct: 1268 AA--TPP 1272
Score = 46.2 bits (108), Expect = 2e-04
Identities = 103/419 (24%), Positives = 143/419 (34%), Gaps = 97/419 (23%)
Query: 116 PPPPEVIPEPEVSTQPPPEEP--------GCGSETVPVPDGPR------SDSVEGSPFRP 161
P + +P+P+ T P G T+P P P S + + SPF
Sbjct: 10 PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPS 69
Query: 162 PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDS 221
PS S + P +SSGT L TF N G
Sbjct: 70 PSTIASTPLEVPFPQSSSGT-ALPLGTAPEAPTF---------LPNLIGP---------- 109
Query: 222 VPISKSTLSRSLSLQASDFDGASSSGNPEA-VALAPDAYSTGSS--------------SA 266
PIS + L+ + + A G SS P A VALAP + S+ +
Sbjct: 110 -PISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAE 168
Query: 267 SSTLKRTKKPRPPSLKKKQTTKKPTE-TPPVKETQQEPDEESLVP-----------SG-E 313
S ++ P PS K K P+E P K T P S VP SG
Sbjct: 169 SGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVA 228
Query: 314 NLASETKTESAKTEGP------------SPALLEETPLEPAVGPKAACPLDSESAEGVVP 361
+L T T + P SP L+ V P AA L ++S V
Sbjct: 229 SLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTS 288
Query: 362 PASGGGRVQNSPP-----VGRKTLPL-----TTAPEAGEVTPSDSGGQEDSPAKGLSVRL 411
G N+PP +G PL + G+ PS D K +SV
Sbjct: 289 SQKTAG--PNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPS---ALSDPTVKTISV-- 341
Query: 412 EFDYSEDKSSWDNQQENPPP---TKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRS 467
D+S +S+ +Q+ PP ++ VA P+ P + K P + + SP S
Sbjct: 342 --DHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGS 398
Score = 45.4 bits (106), Expect = 3e-04
Identities = 89/435 (20%), Positives = 146/435 (33%), Gaps = 83/435 (19%)
Query: 36 QDTPGSPDHRDASSSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQRSSDS 95
++ P +P ++ASS P AP+ E L+ + S
Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTYKGAPSPKE--------------------LLIPPAVTS 1607
Query: 96 EEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRS---- 151
E P PPA PP PE P P P S P P S
Sbjct: 1608 PSPKEAP-------TPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCK 1660
Query: 152 ------DSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDA 205
+ +G P + + V P ++ I T + + + S A
Sbjct: 1661 MGATVPQASKGLPAKKGPTALKEVLVAPAPESTP---------IITAPTRKGPQTKKSSA 1711
Query: 206 KNQEGKVNTRRKSTDSVPISKSTLSRSLSLQ---ASDFDGASSSGNPEAVALAPDAYSTG 262
+ + K+ P+S + L +Q + G +S +P+ P++ ++
Sbjct: 1712 TSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAST 1771
Query: 263 SSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTE 322
+A++ K KP S+ +PPV +L P + L S
Sbjct: 1772 PLTAAAFEKVLPKPESASV-------SAAPSPPVSLPLAPSPVPTLPPKQQFLPS----- 1819
Query: 323 SAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVP--PASGGGRVQ----NSPPVG 376
SP L+ E+P +P P D + ++P P SGG Q N P
Sbjct: 1820 -------SPGLVLESPSKP------LAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPK 1866
Query: 377 RKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIG 436
+P+ T VT ++ G +S + LE +D + QQ +I
Sbjct: 1867 SAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELE---EQDSTQATTQQAQLAAAAEID 1923
Query: 437 KKPVAKMPLRRPKMK 451
++PV+K R + K
Sbjct: 1924 EEPVSKAKQSRSEKK 1938
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 81.6 bits (200), Expect = 4e-15
Identities = 149/669 (22%), Positives = 228/669 (34%), Gaps = 62/669 (9%)
Query: 102 PESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRP 161
P TT AP P P P +P +T P+EP + P P P+ + P
Sbjct: 286 PAPTTTKSAPTTPKEPAPTTPKKPAPTT---PKEPAPTTPKEPTPTTPKEPAPTTKEPAP 342
Query: 162 PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDS 221
+ A KP ++ E T T EP + K +T
Sbjct: 343 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT-TTKEPSPTTPKEPAPTTTKSAPTTTK 401
Query: 222 VPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKR-----TKKP 276
P +T S + + +++ P A +T A +T K K+P
Sbjct: 402 EPAPTTTKSAPTTPKE---PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 458
Query: 277 RPPSLKK--KQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKT--EGPSPA 332
P + KK T K+P T P KET ++ + E LA T + A T E +P
Sbjct: 459 APTTTKKPAPTTPKEPAPTTP-KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 517
Query: 333 LLEE----TPLEPA-VGPKAACPLDSESAEGVVP----PASGGGRVQNSPPVGRKTLPLT 383
EE TP EPA PKAA P + P P + +P T P
Sbjct: 518 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 577
Query: 384 TAP----EAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKP 439
TAP E TP +E +P + + + DK + + P T K
Sbjct: 578 TAPTTLKEPAPTTPKKPAPKELAPT---TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 634
Query: 440 VAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIP-IAKGTYTFDIDKWDDPNFNPFSS 498
K P P L + P+ PA P KG + DK +
Sbjct: 635 TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 694
Query: 499 TSKMQESPKLPQQSYNFDPDTCDESVDPFK--TSSKTPSSPSKSPASFEIPASAMEA-NG 555
T+ + +P P++ P+T + T++K P++ KSP SA
Sbjct: 695 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 754
Query: 556 VDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHAT 615
++ KTP T + ++ D + T A P+ + T
Sbjct: 755 LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKT 814
Query: 616 DEEKL-AVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYM 674
E K+ A T Q + T D K + + L+ V TK + T E+ M
Sbjct: 815 TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI----------M 864
Query: 675 EKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTA 734
K P++ PK +A ++ +P P + + PT S ++ + +
Sbjct: 865 NK-----PEETAKPKDRAT----NSKATTPKPQKPTKAPKKPT-----STKKPKTMPRVR 910
Query: 735 AKNQHPVPR 743
P PR
Sbjct: 911 KPKTTPTPR 919
Score = 68.2 bits (165), Expect = 4e-11
Identities = 126/605 (20%), Positives = 192/605 (31%), Gaps = 101/605 (16%)
Query: 177 ASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPIS-------KSTL 229
A SG N DF + DT T Q KV+T K T + PI+ S
Sbjct: 88 AGSGLDNGDF-KVTTPDTSTT----------QHNKVSTSPKITTAKPINPRPSLPPNSDT 136
Query: 230 SRSLSL-----------QASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRP 278
S+ SL + + + +S+ E A + S +SA +K
Sbjct: 137 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 196
Query: 279 PSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETP 338
P+ K + TTK P T P + T P E + E + K+ + P+P + P
Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 256
Query: 339 LEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVT---PSD 395
PK P ++ P + P K+ P TT E T P+
Sbjct: 257 ----TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP-TTPKEPAPTTPKKPAP 311
Query: 396 SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 455
+ +E +P + K + P PT K K P K P
Sbjct: 312 TTPKEPAP------------TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP- 358
Query: 456 KLDNTPASP-PRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYN 514
TP P P +P EP P ++ +PK P +
Sbjct: 359 ---TTPKEPAPTTPKEP----------------------APTTTKEPSPTTPKEPAPTTT 393
Query: 515 FDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKT 574
T + P T S + SP + + PA K P T
Sbjct: 394 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 453
Query: 575 DTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTV-- 632
+ + P P ++P P ET P + T EKLA T + T
Sbjct: 454 TPKEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 512
Query: 633 DLEADKQDYPQPSDLSTFVNET-KFSSPTEELDYRNSYEIEYMEKIGSSLPQD--DDAPK 689
+L + P P+ T K ++P ++ + P++ PK
Sbjct: 513 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP------------KEPAPTTPKEPAPTTPK 560
Query: 690 KQALYLMFDTSQESPVKSSPVRMSE-------SPTPCSGSSFEETEALVNTAAKNQHPVP 742
+ A +T+ +P ++P + E P P + E T K P
Sbjct: 561 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 620
Query: 743 RGLAP 747
+G AP
Sbjct: 621 KGTAP 625
Score = 65.5 bits (158), Expect = 3e-10
Identities = 142/686 (20%), Positives = 218/686 (31%), Gaps = 120/686 (17%)
Query: 3 NENSTSDNQRTLSAQTPRSAQPPGNSQN------------IKRKQQDTPG---SPDHRDA 47
N+ STS T PR + PP + + ++ K+ T S D ++
Sbjct: 110 NKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK 169
Query: 48 SSSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPE---- 103
++S I+ + DL +PT ++ ++ A TP+
Sbjct: 170 TTSAKETQSIEKTSAKDL-APTSKV----------LAKPTPKAETTTKGPALTTPKEPTP 218
Query: 104 -------STTPVKAPP----APPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSD 152
STTP + P + P P E P S P+EP + P P P+
Sbjct: 219 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 278
Query: 153 SVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKV 212
+ + P+ + SA +P T + + +E
Sbjct: 279 APTTTKEPAPTTTKSAPTTPKEPA-------------------PTTPKKPAPTTPKEPAP 319
Query: 213 NTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKR 272
T ++ T + P + ++ + ++ P A +T A +T K
Sbjct: 320 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 379
Query: 273 -----TKKPRPPSLKKKQTTKK---PTETPPVKETQQEPDEESLVPSGENLASETKTESA 324
K+P P + K TT K PT T T +EP + + A T E A
Sbjct: 380 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT----KEPAPTTPKEPA 435
Query: 325 KTEGPSPALLEETPLEPA-VGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLT 383
T PA TP EPA PK P ++ P + + P K L T
Sbjct: 436 PTTPKKPA--PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 493
Query: 384 TAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKM 443
T + TP + PA L E+ + E P PT K A
Sbjct: 494 TPEKLAPTTP-------EKPAPTTPEELAPTTPEEPT--PTTPEEPAPTT---PKAAAPN 541
Query: 444 PLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQ 503
+ P E TP P + + KGT + + P +T K
Sbjct: 542 TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE-------PAPTTPKKP 594
Query: 504 ESPKL-PQQSYNFDPDTCDE----------SVDPFKTSSKTPSSPSKSPASFEIPASAME 552
+L P + TCD+ P + + TP P+ + P + E
Sbjct: 595 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 654
Query: 553 ANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTP------------AA 600
KPA K+ P T S K +P + + TP
Sbjct: 655 PAPTTP---KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 711
Query: 601 TPETPPVISAVVHATDEEKLAVTNQK 626
TPETPP ++ V K T K
Sbjct: 712 TPETPPPTTSEVSTPTTTKEPTTIHK 737
Score = 57.0 bits (136), Expect = 1e-07
Identities = 106/514 (20%), Positives = 169/514 (32%), Gaps = 67/514 (13%)
Query: 282 KKKQTTKKPTETPPVKETQQEPDEESLVPSGENLAS--ETKTESAKTEGPSPALLEETPL 339
KK +T KKPT PPV + + S + +G+ + +T T SP + P
Sbjct: 70 KKNRTKKKPTPKPPVVD-----EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP- 123
Query: 340 EPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQ 399
+ P+ + P +S++++ + S V ++ T E E T ++
Sbjct: 124 ---INPRPSLPPNSDTSK------------ETSLTVNKE-----TTVETKETTTTNKQTS 163
Query: 400 EDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPV--AKMPLRRPKMKKTPEKL 457
D K S + E +S ++ PT K+ KP A+ + P + E
Sbjct: 164 TDGKEKTTSAK------ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT 217
Query: 458 DNTPASP-PRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFD 516
TP P +P EP I T P ++T +PK P + +
Sbjct: 218 PTTPKEPASTTPKEPTPTTIKSAPTT--------PKEPAPTTTKSAPTTPKEPAPTTTKE 269
Query: 517 P-DTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTD 575
P T + P T P++ +P + + PA P + T K
Sbjct: 270 PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP----TTPKEPAPTTPKEP 325
Query: 576 TFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLE 635
T K P P +++P P E P T ++ A T K T E
Sbjct: 326 TPTTPKEPA------PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 379
Query: 636 AD--KQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQAL 693
P P+ + TK +PT + + P P
Sbjct: 380 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 439
Query: 694 YLMFDTSQESPVKSSPVRMSESPTPCSGSSFEET---EALVNTAAKNQHPVPRGLAPNQE 750
T+ + P ++P + P P + T E T + P+ L P
Sbjct: 440 KKPAPTTPKEPAPTTP----KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 495
Query: 751 SHL--QVPEKSSQKELEAMGLGTPSEAIEITAPE 782
L PEK + E + TP E T E
Sbjct: 496 EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 529
Score = 54.7 bits (130), Expect = 5e-07
Identities = 133/638 (20%), Positives = 209/638 (32%), Gaps = 75/638 (11%)
Query: 18 TPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPADLESPTLAASSYHG 77
TP+ P + ++ P +P A ++P P PA +P A +
Sbjct: 321 TPKEPTPTTPKEPAPTTKEPAPTTPKE-PAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTK 378
Query: 78 DVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVST--QPPPEE 135
+ + + + + P TT AP P P P EP +T +P P
Sbjct: 379 EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 438
Query: 136 PGCGSETVP---VPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELV 192
P + T P P P+ + + P+ K A + L E +
Sbjct: 439 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 498
Query: 193 DTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNPEA 251
T + + +E T + T + P + T ++ + ++ P
Sbjct: 499 AP--TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 556
Query: 252 VALAPDAYSTGSSSASSTLKRT-----KKPRPPSLKKKQ-------TTKKPTETPPVKET 299
A +T +A +T K T K+P P + KK TTK+PT T K
Sbjct: 557 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 616
Query: 300 QQEPDEESLVPSGENLASETKTESAKT-EGPSPALLEE----TPLEPAVGPKAACPLDSE 354
P + E + K + T +G +P L+E TP +PA PK P ++
Sbjct: 617 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTK 674
Query: 355 SAEGVVP----PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVR 410
P + +P T P AP E P + E S
Sbjct: 675 GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS--EVSTPTTTKEP 732
Query: 411 LEFDYSEDKSSWDNQQENPPPTKKIGKK----PVAKMPLR-RPKM------KKTPEKLDN 459
S D+S+ + E P + K P K P +P+M K T L
Sbjct: 733 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 792
Query: 460 TPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDT 519
TP + +P + K T T T++ + + Q + DT
Sbjct: 793 TPETTTAAPK------MTKETATTT------------EKTTESKITATTTQVTSTTTQDT 834
Query: 520 CDESVDPFKTSSKTP--SSPSKSPASFEIPASAMEANGVDGDGLN------KPAKKKKTP 571
+ KT++ P ++ K+ + EI E N KP K K P
Sbjct: 835 TPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAP 894
Query: 572 LKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVIS 609
K + K PK P P PTP T P ++
Sbjct: 895 KKPTS---TKKPKTMPRVRKPKTTPTPRKMTSTMPELN 929
Score = 48.5 bits (114), Expect = 3e-05
Identities = 96/494 (19%), Positives = 163/494 (32%), Gaps = 62/494 (12%)
Query: 100 ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQP------PPEEPGCGSETVPVPDGPRSDS 153
E P TTP + P P P PE T P P+EP + P P P+
Sbjct: 504 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--- 560
Query: 154 VEGSPFRP-------PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAK 206
E +P P P + E P + + T + +
Sbjct: 561 -EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 619
Query: 207 NQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNPEAVALAPDA----YST 261
+ T ++ + P + T + + ++ P LAP ST
Sbjct: 620 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 679
Query: 262 GSSSASSTLKRTKKPRPPSLKKKQTTKKPT----ETPPVKETQQEPDEESLVPSGENLAS 317
S + T + P P T KKP ETPP ++ + P+ + +
Sbjct: 680 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 739
Query: 318 ETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGR 377
+ T E P+P LE +P EP V P P P +
Sbjct: 740 DESTPELSAE-PTPKALENSPKEPGV-PTTKTP-------AATKPEMTTTAKDKTTERDL 790
Query: 378 KTLPLTT--APEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKI 435
+T P TT AP+ + T + + +S + ++ ++D + +
Sbjct: 791 RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF------------- 837
Query: 436 GKKPVAKMPLRRPKMKKTPEKLDNTP-ASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFN 494
K K PK+ T + + T + P A+P D T K
Sbjct: 838 -KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKK 896
Query: 495 PFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSK-------TPSSPSKSPAS--FE 545
P +ST K + P++ + P ++ +S+ T + P+++P S E
Sbjct: 897 P-TSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 955
Query: 546 IPASAMEANGVDGD 559
+ + +A G +G+
Sbjct: 956 VNPKSEDAGGAEGE 969
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 81.6 bits (200), Expect = 4e-15
Identities = 149/669 (22%), Positives = 228/669 (34%), Gaps = 62/669 (9%)
Query: 102 PESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRP 161
P TT AP P P P +P +T P+EP + P P P+ + P
Sbjct: 327 PAPTTTKSAPTTPKEPAPTTPKKPAPTT---PKEPAPTTPKEPTPTTPKEPAPTTKEPAP 383
Query: 162 PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDS 221
+ A KP ++ E T T EP + K +T
Sbjct: 384 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT-TTKEPSPTTPKEPAPTTTKSAPTTTK 442
Query: 222 VPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKR-----TKKP 276
P +T S + + +++ P A +T A +T K K+P
Sbjct: 443 EPAPTTTKSAPTTPKE---PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 499
Query: 277 RPPSLKK--KQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKT--EGPSPA 332
P + KK T K+P T P KET ++ + E LA T + A T E +P
Sbjct: 500 APTTTKKPAPTTPKEPAPTTP-KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 558
Query: 333 LLEE----TPLEPA-VGPKAACPLDSESAEGVVP----PASGGGRVQNSPPVGRKTLPLT 383
EE TP EPA PKAA P + P P + +P T P
Sbjct: 559 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 618
Query: 384 TAP----EAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKP 439
TAP E TP +E +P + + + DK + + P T K
Sbjct: 619 TAPTTLKEPAPTTPKKPAPKELAPT---TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 675
Query: 440 VAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIP-IAKGTYTFDIDKWDDPNFNPFSS 498
K P P L + P+ PA P KG + DK +
Sbjct: 676 TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 735
Query: 499 TSKMQESPKLPQQSYNFDPDTCDESVDPFK--TSSKTPSSPSKSPASFEIPASAMEA-NG 555
T+ + +P P++ P+T + T++K P++ KSP SA
Sbjct: 736 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 795
Query: 556 VDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHAT 615
++ KTP T + ++ D + T A P+ + T
Sbjct: 796 LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKT 855
Query: 616 DEEKL-AVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYM 674
E K+ A T Q + T D K + + L+ V TK + T E+ M
Sbjct: 856 TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI----------M 905
Query: 675 EKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTA 734
K P++ PK +A ++ +P P + + PT S ++ + +
Sbjct: 906 NK-----PEETAKPKDRAT----NSKATTPKPQKPTKAPKKPT-----STKKPKTMPRVR 951
Query: 735 AKNQHPVPR 743
P PR
Sbjct: 952 KPKTTPTPR 960
Score = 68.2 bits (165), Expect = 4e-11
Identities = 126/605 (20%), Positives = 192/605 (31%), Gaps = 101/605 (16%)
Query: 177 ASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPIS-------KSTL 229
A SG N DF + DT T Q KV+T K T + PI+ S
Sbjct: 129 AGSGLDNGDF-KVTTPDTSTT----------QHNKVSTSPKITTAKPINPRPSLPPNSDT 177
Query: 230 SRSLSL-----------QASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRP 278
S+ SL + + + +S+ E A + S +SA +K
Sbjct: 178 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 237
Query: 279 PSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETP 338
P+ K + TTK P T P + T P E + E + K+ + P+P + P
Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 297
Query: 339 LEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVT---PSD 395
PK P ++ P + P K+ P TT E T P+
Sbjct: 298 ----TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP-TTPKEPAPTTPKKPAP 352
Query: 396 SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 455
+ +E +P + K + P PT K K P K P
Sbjct: 353 TTPKEPAP------------TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP- 399
Query: 456 KLDNTPASP-PRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYN 514
TP P P +P EP P ++ +PK P +
Sbjct: 400 ---TTPKEPAPTTPKEP----------------------APTTTKEPSPTTPKEPAPTTT 434
Query: 515 FDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKT 574
T + P T S + SP + + PA K P T
Sbjct: 435 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 494
Query: 575 DTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTV-- 632
+ + P P ++P P ET P + T EKLA T + T
Sbjct: 495 TPKEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 553
Query: 633 DLEADKQDYPQPSDLSTFVNET-KFSSPTEELDYRNSYEIEYMEKIGSSLPQD--DDAPK 689
+L + P P+ T K ++P ++ + P++ PK
Sbjct: 554 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP------------KEPAPTTPKEPAPTTPK 601
Query: 690 KQALYLMFDTSQESPVKSSPVRMSE-------SPTPCSGSSFEETEALVNTAAKNQHPVP 742
+ A +T+ +P ++P + E P P + E T K P
Sbjct: 602 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 661
Query: 743 RGLAP 747
+G AP
Sbjct: 662 KGTAP 666
Score = 65.5 bits (158), Expect = 3e-10
Identities = 142/686 (20%), Positives = 218/686 (31%), Gaps = 120/686 (17%)
Query: 3 NENSTSDNQRTLSAQTPRSAQPPGNSQN------------IKRKQQDTPG---SPDHRDA 47
N+ STS T PR + PP + + ++ K+ T S D ++
Sbjct: 151 NKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK 210
Query: 48 SSSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPE---- 103
++S I+ + DL +PT ++ ++ A TP+
Sbjct: 211 TTSAKETQSIEKTSAKDL-APTSKV----------LAKPTPKAETTTKGPALTTPKEPTP 259
Query: 104 -------STTPVKAPP----APPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSD 152
STTP + P + P P E P S P+EP + P P P+
Sbjct: 260 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 319
Query: 153 SVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKV 212
+ + P+ + SA +P T + + +E
Sbjct: 320 APTTTKEPAPTTTKSAPTTPKEPA-------------------PTTPKKPAPTTPKEPAP 360
Query: 213 NTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKR 272
T ++ T + P + ++ + ++ P A +T A +T K
Sbjct: 361 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 420
Query: 273 -----TKKPRPPSLKKKQTTKK---PTETPPVKETQQEPDEESLVPSGENLASETKTESA 324
K+P P + K TT K PT T T +EP + + A T E A
Sbjct: 421 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT----KEPAPTTPKEPA 476
Query: 325 KTEGPSPALLEETPLEPA-VGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLT 383
T PA TP EPA PK P ++ P + + P K L T
Sbjct: 477 PTTPKKPA--PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 534
Query: 384 TAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKM 443
T + TP + PA L E+ + E P PT K A
Sbjct: 535 TPEKLAPTTP-------EKPAPTTPEELAPTTPEEPT--PTTPEEPAPTT---PKAAAPN 582
Query: 444 PLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQ 503
+ P E TP P + + KGT + + P +T K
Sbjct: 583 TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE-------PAPTTPKKP 635
Query: 504 ESPKL-PQQSYNFDPDTCDE----------SVDPFKTSSKTPSSPSKSPASFEIPASAME 552
+L P + TCD+ P + + TP P+ + P + E
Sbjct: 636 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 695
Query: 553 ANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTP------------AA 600
KPA K+ P T S K +P + + TP
Sbjct: 696 PAPTTP---KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 752
Query: 601 TPETPPVISAVVHATDEEKLAVTNQK 626
TPETPP ++ V K T K
Sbjct: 753 TPETPPPTTSEVSTPTTTKEPTTIHK 778
Score = 57.0 bits (136), Expect = 1e-07
Identities = 106/514 (20%), Positives = 169/514 (32%), Gaps = 67/514 (13%)
Query: 282 KKKQTTKKPTETPPVKETQQEPDEESLVPSGENLAS--ETKTESAKTEGPSPALLEETPL 339
KK +T KKPT PPV + + S + +G+ + +T T SP + P
Sbjct: 111 KKNRTKKKPTPKPPVVD-----EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP- 164
Query: 340 EPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQ 399
+ P+ + P +S++++ + S V ++ T E E T ++
Sbjct: 165 ---INPRPSLPPNSDTSK------------ETSLTVNKE-----TTVETKETTTTNKQTS 204
Query: 400 EDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPV--AKMPLRRPKMKKTPEKL 457
D K S + E +S ++ PT K+ KP A+ + P + E
Sbjct: 205 TDGKEKTTSAK------ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT 258
Query: 458 DNTPASP-PRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFD 516
TP P +P EP I T P ++T +PK P + +
Sbjct: 259 PTTPKEPASTTPKEPTPTTIKSAPTT--------PKEPAPTTTKSAPTTPKEPAPTTTKE 310
Query: 517 P-DTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTD 575
P T + P T P++ +P + + PA P + T K
Sbjct: 311 PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP----TTPKEPAPTTPKEP 366
Query: 576 TFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLE 635
T K P P +++P P E P T ++ A T K T E
Sbjct: 367 TPTTPKEPA------PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 420
Query: 636 AD--KQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQAL 693
P P+ + TK +PT + + P P
Sbjct: 421 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 480
Query: 694 YLMFDTSQESPVKSSPVRMSESPTPCSGSSFEET---EALVNTAAKNQHPVPRGLAPNQE 750
T+ + P ++P + P P + T E T + P+ L P
Sbjct: 481 KKPAPTTPKEPAPTTP----KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 536
Query: 751 SHL--QVPEKSSQKELEAMGLGTPSEAIEITAPE 782
L PEK + E + TP E T E
Sbjct: 537 EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 570
Score = 54.7 bits (130), Expect = 5e-07
Identities = 133/638 (20%), Positives = 209/638 (32%), Gaps = 75/638 (11%)
Query: 18 TPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPADLESPTLAASSYHG 77
TP+ P + ++ P +P A ++P P PA +P A +
Sbjct: 362 TPKEPTPTTPKEPAPTTKEPAPTTPKE-PAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTK 419
Query: 78 DVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVST--QPPPEE 135
+ + + + + P TT AP P P P EP +T +P P
Sbjct: 420 EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 479
Query: 136 PGCGSETVP---VPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELV 192
P + T P P P+ + + P+ K A + L E +
Sbjct: 480 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 539
Query: 193 DTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNPEA 251
T + + +E T + T + P + T ++ + ++ P
Sbjct: 540 AP--TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 597
Query: 252 VALAPDAYSTGSSSASSTLKRT-----KKPRPPSLKKKQ-------TTKKPTETPPVKET 299
A +T +A +T K T K+P P + KK TTK+PT T K
Sbjct: 598 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 657
Query: 300 QQEPDEESLVPSGENLASETKTESAKT-EGPSPALLEE----TPLEPAVGPKAACPLDSE 354
P + E + K + T +G +P L+E TP +PA PK P ++
Sbjct: 658 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTK 715
Query: 355 SAEGVVP----PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVR 410
P + +P T P AP E P + E S
Sbjct: 716 GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS--EVSTPTTTKEP 773
Query: 411 LEFDYSEDKSSWDNQQENPPPTKKIGKK----PVAKMPLR-RPKM------KKTPEKLDN 459
S D+S+ + E P + K P K P +P+M K T L
Sbjct: 774 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 833
Query: 460 TPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDT 519
TP + +P + K T T T++ + + Q + DT
Sbjct: 834 TPETTTAAPK------MTKETATTT------------EKTTESKITATTTQVTSTTTQDT 875
Query: 520 CDESVDPFKTSSKTP--SSPSKSPASFEIPASAMEANGVDGDGLN------KPAKKKKTP 571
+ KT++ P ++ K+ + EI E N KP K K P
Sbjct: 876 TPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAP 935
Query: 572 LKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVIS 609
K + K PK P P PTP T P ++
Sbjct: 936 KKPTS---TKKPKTMPRVRKPKTTPTPRKMTSTMPELN 970
Score = 48.5 bits (114), Expect = 3e-05
Identities = 96/494 (19%), Positives = 163/494 (32%), Gaps = 62/494 (12%)
Query: 100 ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQP------PPEEPGCGSETVPVPDGPRSDS 153
E P TTP + P P P PE T P P+EP + P P P+
Sbjct: 545 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--- 601
Query: 154 VEGSPFRP-------PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAK 206
E +P P P + E P + + T + +
Sbjct: 602 -EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 660
Query: 207 NQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNPEAVALAPDA----YST 261
+ T ++ + P + T + + ++ P LAP ST
Sbjct: 661 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 720
Query: 262 GSSSASSTLKRTKKPRPPSLKKKQTTKKPT----ETPPVKETQQEPDEESLVPSGENLAS 317
S + T + P P T KKP ETPP ++ + P+ + +
Sbjct: 721 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 780
Query: 318 ETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGR 377
+ T E P+P LE +P EP V P P P +
Sbjct: 781 DESTPELSAE-PTPKALENSPKEPGV-PTTKTP-------AATKPEMTTTAKDKTTERDL 831
Query: 378 KTLPLTT--APEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKI 435
+T P TT AP+ + T + + +S + ++ ++D + +
Sbjct: 832 RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF------------- 878
Query: 436 GKKPVAKMPLRRPKMKKTPEKLDNTP-ASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFN 494
K K PK+ T + + T + P A+P D T K
Sbjct: 879 -KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKK 937
Query: 495 PFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSK-------TPSSPSKSPAS--FE 545
P +ST K + P++ + P ++ +S+ T + P+++P S E
Sbjct: 938 P-TSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 996
Query: 546 IPASAMEANGVDGD 559
+ + +A G +G+
Sbjct: 997 VNPKSEDAGGAEGE 1010
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 81.6 bits (200), Expect = 4e-15
Identities = 149/669 (22%), Positives = 228/669 (34%), Gaps = 62/669 (9%)
Query: 102 PESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRP 161
P TT AP P P P +P +T P+EP + P P P+ + P
Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPKKPAPTT---PKEPAPTTPKEPTPTTPKEPAPTTKEPAP 435
Query: 162 PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDS 221
+ A KP ++ E T T EP + K +T
Sbjct: 436 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT-TTKEPSPTTPKEPAPTTTKSAPTTTK 494
Query: 222 VPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKR-----TKKP 276
P +T S + + +++ P A +T A +T K K+P
Sbjct: 495 EPAPTTTKSAPTTPKE---PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 551
Query: 277 RPPSLKK--KQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKT--EGPSPA 332
P + KK T K+P T P KET ++ + E LA T + A T E +P
Sbjct: 552 APTTTKKPAPTTPKEPAPTTP-KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 610
Query: 333 LLEE----TPLEPA-VGPKAACPLDSESAEGVVP----PASGGGRVQNSPPVGRKTLPLT 383
EE TP EPA PKAA P + P P + +P T P
Sbjct: 611 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 670
Query: 384 TAP----EAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKP 439
TAP E TP +E +P + + + DK + + P T K
Sbjct: 671 TAPTTLKEPAPTTPKKPAPKELAPT---TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 727
Query: 440 VAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIP-IAKGTYTFDIDKWDDPNFNPFSS 498
K P P L + P+ PA P KG + DK +
Sbjct: 728 TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 787
Query: 499 TSKMQESPKLPQQSYNFDPDTCDESVDPFK--TSSKTPSSPSKSPASFEIPASAMEA-NG 555
T+ + +P P++ P+T + T++K P++ KSP SA
Sbjct: 788 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 847
Query: 556 VDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHAT 615
++ KTP T + ++ D + T A P+ + T
Sbjct: 848 LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKT 907
Query: 616 DEEKL-AVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYM 674
E K+ A T Q + T D K + + L+ V TK + T E+ M
Sbjct: 908 TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI----------M 957
Query: 675 EKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTA 734
K P++ PK +A ++ +P P + + PT S ++ + +
Sbjct: 958 NK-----PEETAKPKDRAT----NSKATTPKPQKPTKAPKKPT-----STKKPKTMPRVR 1003
Query: 735 AKNQHPVPR 743
P PR
Sbjct: 1004 KPKTTPTPR 1012
Score = 70.9 bits (172), Expect = 6e-12
Identities = 144/766 (18%), Positives = 249/766 (32%), Gaps = 129/766 (16%)
Query: 4 ENSTSDNQRTLSAQTPRSAQPP-GNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAP 62
E+ ++ S + + A PP G SQ IK + +P P+ + +++I + +
Sbjct: 60 ESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSV 119
Query: 63 AD-LESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPEV 121
++ ES + ++SS + ++ + + + + ++ + ++ + P P PP V
Sbjct: 120 SENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKN-RTKKKPTPKPPVV 178
Query: 122 IPEPEVSTQPPPEEPGCGSET----VPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIA 177
+E G G + V PD
Sbjct: 179 ------------DEAGSGLDNGDFKVTTPD------------------------------ 196
Query: 178 SSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQA 237
+S T + + T + + PR S N + T S+ ++K T + +
Sbjct: 197 TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET------SLTVNKETTVETK--ET 248
Query: 238 SDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVK 297
+ + +S+ E A + S +SA +K P+ K + TTK P T P +
Sbjct: 249 TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE 308
Query: 298 ETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAE 357
T P E + E + K+ + P+P + P PK P ++
Sbjct: 309 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP----TTPKEPAPTTTKEPA 364
Query: 358 GVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVT---PSDSGGQEDSPAKGLSVRLEFD 414
P + P K+ P TT E T P+ + +E +P
Sbjct: 365 PTTPKEPAPTTTKEPAPTTTKSAP-TTPKEPAPTTPKKPAPTTPKEPAP----------- 412
Query: 415 YSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASP-PRSPAEPND 473
+ K + P PT K K P K P TP P P +P EP
Sbjct: 413 -TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP----TTPKEPAPTTPKEP-- 465
Query: 474 IPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKT 533
P ++ +PK P + T + P T S
Sbjct: 466 --------------------APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 505
Query: 534 PSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPS 593
+ SP + + PA K P T + + P P
Sbjct: 506 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP- 564
Query: 594 QDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTV--DLEADKQDYPQPSDLSTFV 651
++P P ET P + T EKLA T + T +L + P P+
Sbjct: 565 KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 624
Query: 652 NET-KFSSPTEELDYRNSYEIEYMEKIGSSLPQD--DDAPKKQALYLMFDTSQESPVKSS 708
T K ++P ++ + P++ PK+ A +T+ +P ++
Sbjct: 625 PTTPKAAAPNTP------------KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 672
Query: 709 PVRMSE-------SPTPCSGSSFEETEALVNTAAKNQHPVPRGLAP 747
P + E P P + E T K P+G AP
Sbjct: 673 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718
Score = 65.5 bits (158), Expect = 3e-10
Identities = 142/686 (20%), Positives = 218/686 (31%), Gaps = 120/686 (17%)
Query: 3 NENSTSDNQRTLSAQTPRSAQPPGNSQN------------IKRKQQDTPG---SPDHRDA 47
N+ STS T PR + PP + + ++ K+ T S D ++
Sbjct: 203 NKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK 262
Query: 48 SSSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPE---- 103
++S I+ + DL +PT ++ ++ A TP+
Sbjct: 263 TTSAKETQSIEKTSAKDL-APTSKV----------LAKPTPKAETTTKGPALTTPKEPTP 311
Query: 104 -------STTPVKAPP----APPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSD 152
STTP + P + P P E P S P+EP + P P P+
Sbjct: 312 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 371
Query: 153 SVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKV 212
+ + P+ + SA +P T + + +E
Sbjct: 372 APTTTKEPAPTTTKSAPTTPKEPA-------------------PTTPKKPAPTTPKEPAP 412
Query: 213 NTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKR 272
T ++ T + P + ++ + ++ P A +T A +T K
Sbjct: 413 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 472
Query: 273 -----TKKPRPPSLKKKQTTKK---PTETPPVKETQQEPDEESLVPSGENLASETKTESA 324
K+P P + K TT K PT T T +EP + + A T E A
Sbjct: 473 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT----KEPAPTTPKEPA 528
Query: 325 KTEGPSPALLEETPLEPA-VGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLT 383
T PA TP EPA PK P ++ P + + P K L T
Sbjct: 529 PTTPKKPA--PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 586
Query: 384 TAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKM 443
T + TP + PA L E+ + E P PT K A
Sbjct: 587 TPEKLAPTTP-------EKPAPTTPEELAPTTPEEPT--PTTPEEPAPTT---PKAAAPN 634
Query: 444 PLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQ 503
+ P E TP P + + KGT + + P +T K
Sbjct: 635 TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE-------PAPTTPKKP 687
Query: 504 ESPKL-PQQSYNFDPDTCDE----------SVDPFKTSSKTPSSPSKSPASFEIPASAME 552
+L P + TCD+ P + + TP P+ + P + E
Sbjct: 688 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 747
Query: 553 ANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTP------------AA 600
KPA K+ P T S K +P + + TP
Sbjct: 748 PAPTTP---KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 804
Query: 601 TPETPPVISAVVHATDEEKLAVTNQK 626
TPETPP ++ V K T K
Sbjct: 805 TPETPPPTTSEVSTPTTTKEPTTIHK 830
Score = 63.5 bits (153), Expect = 1e-09
Identities = 125/613 (20%), Positives = 206/613 (33%), Gaps = 87/613 (14%)
Query: 197 TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDF-DGASSSGNPEAVALA 255
T P + A G T + +T P + +++ + + S S N E+ +
Sbjct: 70 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS-- 127
Query: 256 PDAYSTGSSSASSTLKRTKKPRPPSL-------------KKKQTTKKPTETPPVKETQQE 302
S+ SSS+SST+++ K + + KK +T KKPT PPV +
Sbjct: 128 ----SSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVD---- 179
Query: 303 PDEESLVPSGENLAS--ETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVV 360
+ S + +G+ + +T T SP + P + P+ + P +S++++
Sbjct: 180 -EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP----INPRPSLPPNSDTSK--- 231
Query: 361 PPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKS 420
+ S V ++ T E E T ++ D K S + E +S
Sbjct: 232 ---------ETSLTVNKE-----TTVETKETTTTNKQTSTDGKEKTTSAK------ETQS 271
Query: 421 SWDNQQENPPPTKKIGKKPV--AKMPLRRPKMKKTPEKLDNTPASP-PRSPAEPNDIPIA 477
++ PT K+ KP A+ + P + E TP P +P EP I
Sbjct: 272 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 331
Query: 478 KGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDP-DTCDESVDPFKTSSKTPSS 536
T P ++T +PK P + +P T + P T P++
Sbjct: 332 SAPTT--------PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 383
Query: 537 PSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDP 596
+P + + PA P + T K T K P P +++P
Sbjct: 384 TKSAPTTPKEPAPTTPKKPAP----TTPKEPAPTTPKEPTPTTPKEPA------PTTKEP 433
Query: 597 TPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEAD--KQDYPQPSDLSTFVNET 654
P E P T ++ A T K T E P P+ + T
Sbjct: 434 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 493
Query: 655 KFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSE 714
K +PT + + P P T+ + P ++P +
Sbjct: 494 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP----K 549
Query: 715 SPTPCSGSSFEET---EALVNTAAKNQHPVPRGLAPNQESHL--QVPEKSSQKELEAMGL 769
P P + T E T + P+ L P L PEK + E +
Sbjct: 550 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 609
Query: 770 GTPSEAIEITAPE 782
TP E T E
Sbjct: 610 TTPEEPTPTTPEE 622
Score = 54.7 bits (130), Expect = 5e-07
Identities = 133/638 (20%), Positives = 209/638 (32%), Gaps = 75/638 (11%)
Query: 18 TPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPADLESPTLAASSYHG 77
TP+ P + ++ P +P A ++P P PA +P A +
Sbjct: 414 TPKEPTPTTPKEPAPTTKEPAPTTPKE-PAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTK 471
Query: 78 DVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVST--QPPPEE 135
+ + + + + P TT AP P P P EP +T +P P
Sbjct: 472 EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 531
Query: 136 PGCGSETVP---VPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELV 192
P + T P P P+ + + P+ K A + L E +
Sbjct: 532 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 591
Query: 193 DTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNPEA 251
T + + +E T + T + P + T ++ + ++ P
Sbjct: 592 AP--TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 649
Query: 252 VALAPDAYSTGSSSASSTLKRT-----KKPRPPSLKKKQ-------TTKKPTETPPVKET 299
A +T +A +T K T K+P P + KK TTK+PT T K
Sbjct: 650 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 709
Query: 300 QQEPDEESLVPSGENLASETKTESAKT-EGPSPALLEE----TPLEPAVGPKAACPLDSE 354
P + E + K + T +G +P L+E TP +PA PK P ++
Sbjct: 710 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTK 767
Query: 355 SAEGVVP----PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVR 410
P + +P T P AP E P + E S
Sbjct: 768 GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS--EVSTPTTTKEP 825
Query: 411 LEFDYSEDKSSWDNQQENPPPTKKIGKK----PVAKMPLR-RPKM------KKTPEKLDN 459
S D+S+ + E P + K P K P +P+M K T L
Sbjct: 826 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 885
Query: 460 TPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDT 519
TP + +P + K T T T++ + + Q + DT
Sbjct: 886 TPETTTAAPK------MTKETATTT------------EKTTESKITATTTQVTSTTTQDT 927
Query: 520 CDESVDPFKTSSKTP--SSPSKSPASFEIPASAMEANGVDGDGLN------KPAKKKKTP 571
+ KT++ P ++ K+ + EI E N KP K K P
Sbjct: 928 TPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAP 987
Query: 572 LKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVIS 609
K + K PK P P PTP T P ++
Sbjct: 988 KKPTS---TKKPKTMPRVRKPKTTPTPRKMTSTMPELN 1022
Score = 48.5 bits (114), Expect = 3e-05
Identities = 96/494 (19%), Positives = 163/494 (32%), Gaps = 62/494 (12%)
Query: 100 ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQP------PPEEPGCGSETVPVPDGPRSDS 153
E P TTP + P P P PE T P P+EP + P P P+
Sbjct: 597 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--- 653
Query: 154 VEGSPFRP-------PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAK 206
E +P P P + E P + + T + +
Sbjct: 654 -EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 712
Query: 207 NQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNPEAVALAPDA----YST 261
+ T ++ + P + T + + ++ P LAP ST
Sbjct: 713 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 772
Query: 262 GSSSASSTLKRTKKPRPPSLKKKQTTKKPT----ETPPVKETQQEPDEESLVPSGENLAS 317
S + T + P P T KKP ETPP ++ + P+ + +
Sbjct: 773 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 832
Query: 318 ETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGR 377
+ T E P+P LE +P EP V P P P +
Sbjct: 833 DESTPELSAE-PTPKALENSPKEPGV-PTTKTP-------AATKPEMTTTAKDKTTERDL 883
Query: 378 KTLPLTT--APEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKI 435
+T P TT AP+ + T + + +S + ++ ++D + +
Sbjct: 884 RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF------------- 930
Query: 436 GKKPVAKMPLRRPKMKKTPEKLDNTP-ASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFN 494
K K PK+ T + + T + P A+P D T K
Sbjct: 931 -KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKK 989
Query: 495 PFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSK-------TPSSPSKSPAS--FE 545
P +ST K + P++ + P ++ +S+ T + P+++P S E
Sbjct: 990 P-TSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 1048
Query: 546 IPASAMEANGVDGD 559
+ + +A G +G+
Sbjct: 1049 VNPKSEDAGGAEGE 1062
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 81.6 bits (200), Expect = 4e-15
Identities = 149/669 (22%), Positives = 228/669 (34%), Gaps = 62/669 (9%)
Query: 102 PESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRP 161
P TT AP P P P +P +T P+EP + P P P+ + P
Sbjct: 420 PAPTTTKSAPTTPKEPAPTTPKKPAPTT---PKEPAPTTPKEPTPTTPKEPAPTTKEPAP 476
Query: 162 PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDS 221
+ A KP ++ E T T EP + K +T
Sbjct: 477 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT-TTKEPSPTTPKEPAPTTTKSAPTTTK 535
Query: 222 VPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKR-----TKKP 276
P +T S + + +++ P A +T A +T K K+P
Sbjct: 536 EPAPTTTKSAPTTPKE---PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 592
Query: 277 RPPSLKK--KQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKT--EGPSPA 332
P + KK T K+P T P KET ++ + E LA T + A T E +P
Sbjct: 593 APTTTKKPAPTTPKEPAPTTP-KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 651
Query: 333 LLEE----TPLEPA-VGPKAACPLDSESAEGVVP----PASGGGRVQNSPPVGRKTLPLT 383
EE TP EPA PKAA P + P P + +P T P
Sbjct: 652 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 711
Query: 384 TAP----EAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKP 439
TAP E TP +E +P + + + DK + + P T K
Sbjct: 712 TAPTTLKEPAPTTPKKPAPKELAPT---TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 768
Query: 440 VAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIP-IAKGTYTFDIDKWDDPNFNPFSS 498
K P P L + P+ PA P KG + DK +
Sbjct: 769 TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 828
Query: 499 TSKMQESPKLPQQSYNFDPDTCDESVDPFK--TSSKTPSSPSKSPASFEIPASAMEA-NG 555
T+ + +P P++ P+T + T++K P++ KSP SA
Sbjct: 829 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 888
Query: 556 VDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHAT 615
++ KTP T + ++ D + T A P+ + T
Sbjct: 889 LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKT 948
Query: 616 DEEKL-AVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYM 674
E K+ A T Q + T D K + + L+ V TK + T E+ M
Sbjct: 949 TESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI----------M 998
Query: 675 EKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTA 734
K P++ PK +A ++ +P P + + PT S ++ + +
Sbjct: 999 NK-----PEETAKPKDRAT----NSKATTPKPQKPTKAPKKPT-----STKKPKTMPRVR 1044
Query: 735 AKNQHPVPR 743
P PR
Sbjct: 1045 KPKTTPTPR 1053
Score = 70.9 bits (172), Expect = 6e-12
Identities = 144/766 (18%), Positives = 249/766 (32%), Gaps = 129/766 (16%)
Query: 4 ENSTSDNQRTLSAQTPRSAQPP-GNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAP 62
E+ ++ S + + A PP G SQ IK + +P P+ + +++I + +
Sbjct: 101 ESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSV 160
Query: 63 AD-LESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPEV 121
++ ES + ++SS + ++ + + + + ++ + ++ + P P PP V
Sbjct: 161 SENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKN-RTKKKPTPKPPVV 219
Query: 122 IPEPEVSTQPPPEEPGCGSET----VPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIA 177
+E G G + V PD
Sbjct: 220 ------------DEAGSGLDNGDFKVTTPD------------------------------ 237
Query: 178 SSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQA 237
+S T + + T + + PR S N + T S+ ++K T + +
Sbjct: 238 TSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET------SLTVNKETTVETK--ET 289
Query: 238 SDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVK 297
+ + +S+ E A + S +SA +K P+ K + TTK P T P +
Sbjct: 290 TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE 349
Query: 298 ETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAE 357
T P E + E + K+ + P+P + P PK P ++
Sbjct: 350 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP----TTPKEPAPTTTKEPA 405
Query: 358 GVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVT---PSDSGGQEDSPAKGLSVRLEFD 414
P + P K+ P TT E T P+ + +E +P
Sbjct: 406 PTTPKEPAPTTTKEPAPTTTKSAP-TTPKEPAPTTPKKPAPTTPKEPAP----------- 453
Query: 415 YSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASP-PRSPAEPND 473
+ K + P PT K K P K P TP P P +P EP
Sbjct: 454 -TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP----TTPKEPAPTTPKEP-- 506
Query: 474 IPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKT 533
P ++ +PK P + T + P T S
Sbjct: 507 --------------------APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 546
Query: 534 PSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPS 593
+ SP + + PA K P T + + P P
Sbjct: 547 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP- 605
Query: 594 QDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTV--DLEADKQDYPQPSDLSTFV 651
++P P ET P + T EKLA T + T +L + P P+
Sbjct: 606 KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 665
Query: 652 NET-KFSSPTEELDYRNSYEIEYMEKIGSSLPQD--DDAPKKQALYLMFDTSQESPVKSS 708
T K ++P ++ + P++ PK+ A +T+ +P ++
Sbjct: 666 PTTPKAAAPNTP------------KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 713
Query: 709 PVRMSE-------SPTPCSGSSFEETEALVNTAAKNQHPVPRGLAP 747
P + E P P + E T K P+G AP
Sbjct: 714 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759
Score = 65.5 bits (158), Expect = 3e-10
Identities = 142/686 (20%), Positives = 218/686 (31%), Gaps = 120/686 (17%)
Query: 3 NENSTSDNQRTLSAQTPRSAQPPGNSQN------------IKRKQQDTPG---SPDHRDA 47
N+ STS T PR + PP + + ++ K+ T S D ++
Sbjct: 244 NKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK 303
Query: 48 SSSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPE---- 103
++S I+ + DL +PT ++ ++ A TP+
Sbjct: 304 TTSAKETQSIEKTSAKDL-APTSKV----------LAKPTPKAETTTKGPALTTPKEPTP 352
Query: 104 -------STTPVKAPP----APPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSD 152
STTP + P + P P E P S P+EP + P P P+
Sbjct: 353 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 412
Query: 153 SVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKV 212
+ + P+ + SA +P T + + +E
Sbjct: 413 APTTTKEPAPTTTKSAPTTPKEPA-------------------PTTPKKPAPTTPKEPAP 453
Query: 213 NTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKR 272
T ++ T + P + ++ + ++ P A +T A +T K
Sbjct: 454 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 513
Query: 273 -----TKKPRPPSLKKKQTTKK---PTETPPVKETQQEPDEESLVPSGENLASETKTESA 324
K+P P + K TT K PT T T +EP + + A T E A
Sbjct: 514 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT----KEPAPTTPKEPA 569
Query: 325 KTEGPSPALLEETPLEPA-VGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLT 383
T PA TP EPA PK P ++ P + + P K L T
Sbjct: 570 PTTPKKPA--PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 627
Query: 384 TAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKM 443
T + TP + PA L E+ + E P PT K A
Sbjct: 628 TPEKLAPTTP-------EKPAPTTPEELAPTTPEEPT--PTTPEEPAPTT---PKAAAPN 675
Query: 444 PLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQ 503
+ P E TP P + + KGT + + P +T K
Sbjct: 676 TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE-------PAPTTPKKP 728
Query: 504 ESPKL-PQQSYNFDPDTCDE----------SVDPFKTSSKTPSSPSKSPASFEIPASAME 552
+L P + TCD+ P + + TP P+ + P + E
Sbjct: 729 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 788
Query: 553 ANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTP------------AA 600
KPA K+ P T S K +P + + TP
Sbjct: 789 PAPTTP---KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 845
Query: 601 TPETPPVISAVVHATDEEKLAVTNQK 626
TPETPP ++ V K T K
Sbjct: 846 TPETPPPTTSEVSTPTTTKEPTTIHK 871
Score = 63.5 bits (153), Expect = 1e-09
Identities = 125/613 (20%), Positives = 206/613 (33%), Gaps = 87/613 (14%)
Query: 197 TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDF-DGASSSGNPEAVALA 255
T P + A G T + +T P + +++ + + S S N E+ +
Sbjct: 111 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS-- 168
Query: 256 PDAYSTGSSSASSTLKRTKKPRPPSL-------------KKKQTTKKPTETPPVKETQQE 302
S+ SSS+SST+++ K + + KK +T KKPT PPV +
Sbjct: 169 ----SSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVD---- 220
Query: 303 PDEESLVPSGENLAS--ETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVV 360
+ S + +G+ + +T T SP + P + P+ + P +S++++
Sbjct: 221 -EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP----INPRPSLPPNSDTSK--- 272
Query: 361 PPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKS 420
+ S V ++ T E E T ++ D K S + E +S
Sbjct: 273 ---------ETSLTVNKE-----TTVETKETTTTNKQTSTDGKEKTTSAK------ETQS 312
Query: 421 SWDNQQENPPPTKKIGKKPV--AKMPLRRPKMKKTPEKLDNTPASP-PRSPAEPNDIPIA 477
++ PT K+ KP A+ + P + E TP P +P EP I
Sbjct: 313 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 372
Query: 478 KGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDP-DTCDESVDPFKTSSKTPSS 536
T P ++T +PK P + +P T + P T P++
Sbjct: 373 SAPTT--------PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 424
Query: 537 PSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDP 596
+P + + PA P + T K T K P P +++P
Sbjct: 425 TKSAPTTPKEPAPTTPKKPAP----TTPKEPAPTTPKEPTPTTPKEPA------PTTKEP 474
Query: 597 TPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEAD--KQDYPQPSDLSTFVNET 654
P E P T ++ A T K T E P P+ + T
Sbjct: 475 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 534
Query: 655 KFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSE 714
K +PT + + P P T+ + P ++P +
Sbjct: 535 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP----K 590
Query: 715 SPTPCSGSSFEET---EALVNTAAKNQHPVPRGLAPNQESHL--QVPEKSSQKELEAMGL 769
P P + T E T + P+ L P L PEK + E +
Sbjct: 591 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 650
Query: 770 GTPSEAIEITAPE 782
TP E T E
Sbjct: 651 TTPEEPTPTTPEE 663
Score = 54.7 bits (130), Expect = 5e-07
Identities = 133/638 (20%), Positives = 209/638 (32%), Gaps = 75/638 (11%)
Query: 18 TPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPADLESPTLAASSYHG 77
TP+ P + ++ P +P A ++P P PA +P A +
Sbjct: 455 TPKEPTPTTPKEPAPTTKEPAPTTPKE-PAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTK 512
Query: 78 DVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVST--QPPPEE 135
+ + + + + P TT AP P P P EP +T +P P
Sbjct: 513 EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 572
Query: 136 PGCGSETVP---VPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELV 192
P + T P P P+ + + P+ K A + L E +
Sbjct: 573 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 632
Query: 193 DTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNPEA 251
T + + +E T + T + P + T ++ + ++ P
Sbjct: 633 AP--TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 690
Query: 252 VALAPDAYSTGSSSASSTLKRT-----KKPRPPSLKKKQ-------TTKKPTETPPVKET 299
A +T +A +T K T K+P P + KK TTK+PT T K
Sbjct: 691 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 750
Query: 300 QQEPDEESLVPSGENLASETKTESAKT-EGPSPALLEE----TPLEPAVGPKAACPLDSE 354
P + E + K + T +G +P L+E TP +PA PK P ++
Sbjct: 751 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTK 808
Query: 355 SAEGVVP----PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVR 410
P + +P T P AP E P + E S
Sbjct: 809 GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS--EVSTPTTTKEP 866
Query: 411 LEFDYSEDKSSWDNQQENPPPTKKIGKK----PVAKMPLR-RPKM------KKTPEKLDN 459
S D+S+ + E P + K P K P +P+M K T L
Sbjct: 867 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 926
Query: 460 TPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDT 519
TP + +P + K T T T++ + + Q + DT
Sbjct: 927 TPETTTAAPK------MTKETATTT------------EKTTESKITATTTQVTSTTTQDT 968
Query: 520 CDESVDPFKTSSKTP--SSPSKSPASFEIPASAMEANGVDGDGLN------KPAKKKKTP 571
+ KT++ P ++ K+ + EI E N KP K K P
Sbjct: 969 TPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAP 1028
Query: 572 LKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVIS 609
K + K PK P P PTP T P ++
Sbjct: 1029 KKPTS---TKKPKTMPRVRKPKTTPTPRKMTSTMPELN 1063
Score = 48.5 bits (114), Expect = 3e-05
Identities = 96/494 (19%), Positives = 163/494 (32%), Gaps = 62/494 (12%)
Query: 100 ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQP------PPEEPGCGSETVPVPDGPRSDS 153
E P TTP + P P P PE T P P+EP + P P P+
Sbjct: 638 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--- 694
Query: 154 VEGSPFRP-------PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAK 206
E +P P P + E P + + T + +
Sbjct: 695 -EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 753
Query: 207 NQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNPEAVALAPDA----YST 261
+ T ++ + P + T + + ++ P LAP ST
Sbjct: 754 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 813
Query: 262 GSSSASSTLKRTKKPRPPSLKKKQTTKKPT----ETPPVKETQQEPDEESLVPSGENLAS 317
S + T + P P T KKP ETPP ++ + P+ + +
Sbjct: 814 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 873
Query: 318 ETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGR 377
+ T E P+P LE +P EP V P P P +
Sbjct: 874 DESTPELSAE-PTPKALENSPKEPGV-PTTKTP-------AATKPEMTTTAKDKTTERDL 924
Query: 378 KTLPLTT--APEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKI 435
+T P TT AP+ + T + + +S + ++ ++D + +
Sbjct: 925 RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF------------- 971
Query: 436 GKKPVAKMPLRRPKMKKTPEKLDNTP-ASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFN 494
K K PK+ T + + T + P A+P D T K
Sbjct: 972 -KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKK 1030
Query: 495 PFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSK-------TPSSPSKSPAS--FE 545
P +ST K + P++ + P ++ +S+ T + P+++P S E
Sbjct: 1031 P-TSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 1089
Query: 546 IPASAMEANGVDGD 559
+ + +A G +G+
Sbjct: 1090 VNPKSEDAGGAEGE 1103
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 70.5 bits (171), Expect = 8e-12
Identities = 146/586 (24%), Positives = 201/586 (34%), Gaps = 105/586 (17%)
Query: 102 PESTTPV---KAPPAPPPP----PPEVIPEPEVSTQPP--PEEPGCGSETVP---VPDGP 149
PE PV K P APPP P EV+PE +V PP PE P VP VP+
Sbjct: 10506 PEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKK 10565
Query: 150 RSDSVEGSPFRPPSHSFSAVFD--EDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKN 207
+++ P PP A + +K + ++ + +++ P A
Sbjct: 10566 VPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKV--------PEAPKEVV 10617
Query: 208 QEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGA----------SSSGNPEAVAL-AP 256
E KV VP +K +++ A PE VAL P
Sbjct: 10618 PEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEP 10677
Query: 257 DAYSTGSSSASSTLKRTKKPRPPSLKKKQ---TTKKPTETPPVK--ETQQEPDEESLVPS 311
A ++ + T P+ P +KK KKP E PPVK E +E E VP
Sbjct: 10678 PAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKP-ELPPVKVPEVPKEVVPEKKVP- 10735
Query: 312 GENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQN 371
K E P PA + E P E K A P E VPPA V
Sbjct: 10736 --------LVVPKKPEAP-PAKVPEVPKEVVPEKKVAVPKKPE-----VPPAK-VPEVPK 10780
Query: 372 SPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKS---SWDNQQEN 428
P + K P PE E P + + + A + E E+K + + + E
Sbjct: 10781 KPVLEEK--PAVPVPERAESPPPEVYEEPEEIAPEEEIAPE----EEKPVPVAEEEEPEV 10834
Query: 429 PPPT-----KKI---GKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIP----- 475
PPP KKI K PV K P P + PEK+ P PR P P P
Sbjct: 10835 PPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVK 10894
Query: 476 --------IAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKL-------PQQSYNFD---- 516
I K + P ++ KL P++
Sbjct: 10895 EKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLR 10954
Query: 517 --PDTCDESVDPFKTSS-KTPSSPSKSP----ASFEIPASAMEANGVDGDGLNKPAKKKK 569
P+ + V+P K K P+ P P E+P + + P K
Sbjct: 10955 KRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIP-EPTKVPEIKPA 11013
Query: 570 TPLKTDTFRVKKSPKRSPLSDPPSQ-DPTPAATPETPPVISAVVHA 614
PL + K + + PP + +PTP A P T PV+ A
Sbjct: 11014 IPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEA 11059
Score = 62.8 bits (151), Expect = 2e-09
Identities = 127/563 (22%), Positives = 176/563 (31%), Gaps = 92/563 (16%)
Query: 93 SDSEEAFETPESTTPVKAPPAPPPP------------PPEVIPEPEVSTQPP--PEEPGC 138
S E E P+ P K PA PP P EV+PE +V PP PE P
Sbjct: 10576 SPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPT 10635
Query: 139 GSETVP---VPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTF 195
VP VP+ +++ P PP VF+E + +A L+ E+V
Sbjct: 10636 KVPEVPKVAVPEKKVPEAIPPKPESPPPE----VFEEPEEVA------LEEPPAEVV--- 10682
Query: 196 QTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALA 255
+ EP A K K +V K L + + + P V
Sbjct: 10683 EEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELP-PVKVPEVPKEVVPEKKVPLVVPKK 10741
Query: 256 PDAYSTGSSSA------SSTLKRTKKPRPPSLKKKQTTKKPT--ETP--PVKETQQEP-- 303
P+A + KKP P K + KKP E P PV E + P
Sbjct: 10742 PEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPP 10801
Query: 304 ----DEESLVPSGENLASETK----TESAKTEGPSPALLEE------TPLEPAVGPKAAC 349
+ E + P E E K E + E P PA+ EE P + A
Sbjct: 10802 EVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAP 10861
Query: 350 PLDSESAEGVVPPASGGGRVQNSPPV-----------GRKTLPLTTAPEAGEVTPSDSGG 398
P E V+ R PP K +P PE +V
Sbjct: 10862 PPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQV------- 10914
Query: 399 QEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLD 458
P K L+ E K + P P +++ K V + + K P+KL+
Sbjct: 10915 ----PEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLE 10970
Query: 459 N-----TPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSY 513
P PP P E ++P + P P + PK +
Sbjct: 10971 KVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVK 11030
Query: 514 NFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLK 573
P + P P K+ A +A + G KKTP
Sbjct: 11031 TIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKG-------VPKKTPSP 11083
Query: 574 TDTFRVKKSPKRSPLSDPPSQDP 596
+ R K P S PP + P
Sbjct: 11084 IEAERRKLRP-GSGGEKPPDEAP 11105
Score = 56.2 bits (134), Expect = 2e-07
Identities = 150/719 (20%), Positives = 234/719 (32%), Gaps = 150/719 (20%)
Query: 52 VADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQRSS--DSEEAFETPESTTPV- 108
VA + P P +LE +A + +VV V L+ + EE F T E PV
Sbjct: 9890 VAPPVRVPEVPKELEPEEVA---FEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVI 9946
Query: 109 --KAPPAPPPPPPEV---IPEPEVSTQPP---PEEPGCGSETVPVPDGPRSDSVEGSPFR 160
K P P P PE +P P+ PP PE P E VPV P+ + + P +
Sbjct: 9947 PVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLI-PKKE--KPPPAK 10003
Query: 161 PPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTD 220
P V +E P+ P + KV K
Sbjct: 10004 VPEVPKKPVPEEKVPV-----------------------PVPKKVEAPPAKVPEVPKK-- 10038
Query: 221 SVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPS 280
VP K + ++A P V P + K+ + P P
Sbjct: 10039 PVPEKKVPVPAPKKVEAP----------PAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKV 10088
Query: 281 LKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLE 340
KK++ P P +E EE +VP E L E E P E P E
Sbjct: 10089 PKKREPVPVPVALPQEEEVL---FEEEIVPEEEVLPEE--------EEVLPEEEEVLPEE 10137
Query: 341 PAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQE 400
V P+ E +PP + PP PE E P + E
Sbjct: 10138 EEVLPE----------EEEIPPEE-----EEVPPEEE------YVPEEEEFVPEEEVLPE 10176
Query: 401 DSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNT 460
P + P P +I KK K + P+K +
Sbjct: 10177 VKPKVPV---------------------PAPVPEIKKKVTEKKVV-------IPKKEEAP 10208
Query: 461 PASPPRSP--AEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPD 518
PA P P E I + K ++ ++P P S +E P + + P
Sbjct: 10209 PAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPR 10268
Query: 519 TCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFR 578
P P +P+ P E P A + + + + P +KK+ P
Sbjct: 10269 V------PEVIKKAVPEAPTPVPKKVEAP-PAKVSKKIPEEKVPVPVQKKEAPPAKVPEV 10321
Query: 579 VKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADK 638
KK P++ L P ++ P A T EEK++V ++ + LE +
Sbjct: 10322 PKKVPEKKVL--VPKKEAVPPAKGRT----------VLEEKVSVAFRQEVVVKERLELEV 10369
Query: 639 QDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFD 698
+ +++ E +F E + +E+E K+ +++ +K +
Sbjct: 10370 VE----AEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVF 10425
Query: 699 TSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQVPE 757
++E V P + P E +E ++ P + P +E +VPE
Sbjct: 10426 EAEEVEVFEKPKAPPKGP--------EISEKIIPPKKP-----PTKVVPRKEPPAKVPE 10471
Score = 50.8 bits (120), Expect = 7e-06
Identities = 130/616 (21%), Positives = 217/616 (35%), Gaps = 72/616 (11%)
Query: 274 KKPRPPSLKKKQTTKKPTETPP---VKETQQEPDEESLVPSGENLASETKTESAKTEGPS 330
KKP + +K+ K E P V+E + P+E + P T+ + P
Sbjct: 10453 KKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPP----------TKVPEVLPPK 10502
Query: 331 PALLEE-TPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAG 389
+ E+ P+ PA P+A P E+ + VVP + PP + +P T PE
Sbjct: 10503 EVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPE-----KKVPVPPPKKPEVPPTKVPEVP 10557
Query: 390 EVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPK 449
+ + E P K S E + + + + PP KKP P++ P+
Sbjct: 10558 KAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPP-----KKPEV-TPVKVPE 10611
Query: 450 MKK--TPEKLDNTPASPPRSP-AEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESP 506
K PEK P PP+ P P +P ++ K P + ESP
Sbjct: 10612 APKEVVPEK--KVPVPPPKKPEVPPTKVP--------EVPKVAVPEKKVPEAIPPKPESP 10661
Query: 507 KLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAK 566
P + + + E P++P + + P +A V K
Sbjct: 10662 --PPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAV------VAKK 10713
Query: 567 KKKTPLKTDTFRVKKSP-KRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQ 625
+ P+K + P K+ PL P + PA PE P + E+K+AV +
Sbjct: 10714 PELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEV------VPEKKVAVPKK 10767
Query: 626 KWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQ-- 683
E K+ P + + SP E+ Y EI E+I +
Sbjct: 10768 PEVPPAKVPEVPKK--PVLEEKPAVPVPERAESPPPEV-YEEPEEIAPEEEIAPEEEKPV 10824
Query: 684 ---DDDAPKKQALYLMFDTSQESPVKSSPV-RMSESPTPCSGSSFEETEALVNTAAKNQH 739
+++ P+ + + + P K PV + E+P P E E ++
Sbjct: 10825 PVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPP----KEPEPEKVIEKPKLKPR 10880
Query: 740 PVPRGLAPN----QESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRL 795
P P AP +E Q+ +K E + E + P G L R
Sbjct: 10881 PPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERK 10940
Query: 796 AHPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAK 855
P L E+ P + +KL++ + A+ K ++ + + + ++
Sbjct: 10941 PEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE-- 10998
Query: 856 REAAHPTDVSISKTAL 871
R+ PT V K A+
Sbjct: 10999 RKIPEPTKVPEIKPAI 11014
Score = 49.7 bits (117), Expect = 2e-05
Identities = 147/766 (19%), Positives = 253/766 (33%), Gaps = 142/766 (18%)
Query: 100 ETPESTTPVKAPPAPPPPPPEVIPEPEVS----TQPPPEEPGCGSETVP------VPDGP 149
E+ E P K P PPPP+VI +P + T EE VP VP P
Sbjct: 9159 ESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKP 9218
Query: 150 RSDSVEGSPFR---PPSHSFSAVFDEDKPIASSGTYNLDFDNIELVD----TFQTLEPRA 202
V+ P H+ V E+K +S T + V T + +
Sbjct: 9219 SRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAI 9278
Query: 203 SDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTG 262
S KV + ++ + + + A PE P
Sbjct: 9279 SKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEP 9338
Query: 263 SSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTE 322
++ P+ P + KK ++ P K+ + P + V G +
Sbjct: 9339 AAP----------PKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIV 9388
Query: 323 SAKTEGPSPAL------------------LEETPLEPAVGPKAACPLDSESAEGVVPPAS 364
+ + E P PA+ EE P P V P+ E VP A
Sbjct: 9389 TQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVA- 9447
Query: 365 GGGRVQNSPP----VGRKTL----------PLTTA-PEAGEVTPSDSGGQED----SPAK 405
+ +PP V +KT+ L+ A P+ EVT + +E+ +
Sbjct: 9448 -----KKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEE 9502
Query: 406 GLSVRL---------------EFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKM 450
G+S+ + E++ E+ + +++ +K++ +P + K+
Sbjct: 9503 GVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKI 9562
Query: 451 ---KKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK 507
K P K++ P P + P P I K K P K+ E PK
Sbjct: 9563 VLKPKIPAKIEEPP--PAKVPEAPKKIVPEKKVPAPVPKKEKVP-------PPKVPEEPK 9613
Query: 508 LPQQSYNFDPDTCD-ESVDPFKTSSK-----------TPSSPSKSPASFEIPASAMEANG 555
P P E P K + + + ++P +P A
Sbjct: 9614 KPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVP 9673
Query: 556 VDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHAT 615
+ KP ++++ P K FR + + + P ++P P V
Sbjct: 9674 EEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKE----------VTIM 9723
Query: 616 DEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYME 675
+E++ A T ++ ++V E + ++Y + E + PTEE D YE E
Sbjct: 9724 EEKERAYTLEE-EAVSVQREEEYEEYEEYD-----YKEFEEYEPTEEYDQYEEYEEREYE 9777
Query: 676 KIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAA 735
+ ++ Y+ T E P+ PV PT + + V
Sbjct: 9778 RY-----------EEHEEYI---TEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAV-PEE 9822
Query: 736 KNQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAP 781
K P+P+ L P + P+K ++++ T E ++T P
Sbjct: 9823 KVPVPIPKKLKPPPPKVPEEPKKVFEEKIRIS--ITKREKEQVTEP 9866
Score = 37.0 bits (84), Expect = 0.10
Identities = 30/103 (29%), Positives = 41/103 (39%), Gaps = 14/103 (13%)
Query: 88 IAQRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPE----EPGCGSE-- 141
+ ++ + EE P+ VK P P PPPP+ + E EV T E EP E
Sbjct: 10952 VLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIK 11011
Query: 142 ---TVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGT 181
+P P+ E +PP V E PIA+ T
Sbjct: 11012 PAIPLPAPEPKPKPEAEVKTIKPP-----PVEPEPTPIAAPVT 11049
Score = 35.4 bits (80), Expect = 0.30
Identities = 80/413 (19%), Positives = 138/413 (33%), Gaps = 59/413 (14%)
Query: 17 QTPRSAQPPGNSQNIKRKQQDTPGSPDHRDAS-----SSPVADDIIQPAAPADLESPTLA 71
+ P + P + + K+ P P+ A PV ++ P ESP
Sbjct: 10743 EAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPE 10802
Query: 72 ASSYHGDVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVST-- 129
++ + + + + E+ E P PPA P P ++IPE +V
Sbjct: 10803 VYEEPEEIAPE------EEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIK 10856
Query: 130 ---QPPPEEPGCGSETVPVPDGPR-SDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLD 185
PPP+EP E V + P+ P PP + K I
Sbjct: 10857 KPEAPPPKEP----EPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVP--- 10909
Query: 186 FDNIELVDTFQTLEPRASDAKNQEGKVNTRRK-STDSVPISKSTLSRSLSLQASDFDGAS 244
+ ++ + + + + + K+ RK + KS L + + +
Sbjct: 10910 -EKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKK 10968
Query: 245 -SSGNPEAVALAPDAYSTGSSSASSTLKRTKK-PRP-------PSLKKKQTTKKPTETPP 295
AV P + KR +K P P P++ KP
Sbjct: 10969 LEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAE 11028
Query: 296 VKETQQEPDEESLVPSGENL----------ASETKTESAKTEGPSPALLEETPLEPAVGP 345
VK + P E P + A K E+AK +GP + ++TP
Sbjct: 11029 VKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTP------- 11081
Query: 346 KAACPLDSESAEGVVPPASGGGRVQNSPP--VGRKTLPLTTAPEAGEVTPSDS 396
P+++E + + P SGG + + P K +PL E ++ ++S
Sbjct: 11082 ---SPIEAERRK--LRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTES 11129
Score = 33.9 bits (76), Expect = 0.86
Identities = 97/527 (18%), Positives = 159/527 (30%), Gaps = 82/527 (15%)
Query: 25 PGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVS 84
P + + +++ P + PV ++ I E+P VV +
Sbjct: 9325 PEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEK 9384
Query: 85 TDLIAQRSSDSEEAF-ETPESTTPVKAPPAPP-----PPPPEV--------------IPE 124
++ QR A E P+ P + P P PPPP+V +P
Sbjct: 9385 ITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPV 9444
Query: 125 PEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPS------HSFSA-----VFDED 173
P PPP V + R + E F P H SA +E+
Sbjct: 9445 PVAKKAPPPRAEVSKKTVV---EEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEE 9501
Query: 174 KPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSL 233
+ ++ S + + E + + + E K++ K ++ P +
Sbjct: 9502 EGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKK 9561
Query: 234 SLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRP--PSLKKKQTTKKPT 291
+ P V AP + K+ K P P P KK +K
Sbjct: 9562 IVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEK-- 9619
Query: 292 ETPPVKETQQEPDEESLVPSGENLASETKTESA--KTEGPSPALLEETPLE--------- 340
+ PP +EP + + E K A K E P A + E P
Sbjct: 9620 KVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLK 9679
Query: 341 ---------PAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEV 391
PA + + E + P ++ + K T EA V
Sbjct: 9680 LKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSV 9739
Query: 392 TPSD----------SGGQEDSPAKGLSVRLEFDYS-----EDKSSWDNQQENPPPTKKIG 436
+ +E P + E++ E+ + + E P P K +
Sbjct: 9740 QREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVP 9799
Query: 437 KKPVAKMPLRRPK---MKKTPEKLDNTP------ASPPRSPAEPNDI 474
++PV P P K PE+ P PP+ P EP +
Sbjct: 9800 EEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKV 9846
Score = 31.6 bits (70), Expect = 4.3
Identities = 38/193 (19%), Positives = 84/193 (43%), Gaps = 16/193 (8%)
Query: 892 DLDSALQIARAEIITKEREVSEWKDK-YEESRREVMEMRKIVAEYEKTIAQMIEDEQREK 950
D+ S + + IT+++EV + K+ YE+ + E R + +E+ DE +
Sbjct: 9029 DVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPY-----DELEVE 9083
Query: 951 SVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYL 1010
+ Q E ++ ++ K E +E E F + +E +R + Y
Sbjct: 9084 PYTEPFEQPYYEEPDEDYEEIKVEAKK--------EVHEEWEEDFEEGQEYYER-EEGYD 9134
Query: 1011 SRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTL 1070
++ E+ YQ +V +K + +V K +++A + K+ + ++ +E+T
Sbjct: 9135 EGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPV-IEKIEKTS 9193
Query: 1071 EQKNKEIEELTKI 1083
+ +E ++TK+
Sbjct: 9194 RRMEEEKVQVTKV 9206
Score = 31.2 bits (69), Expect = 5.6
Identities = 22/79 (27%), Positives = 35/79 (44%)
Query: 681 LPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHP 740
LP ++ ++ L DTS + S V+MS S S SSF + A T K
Sbjct: 33224 LPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASM 33283
Query: 741 VPRGLAPNQESHLQVPEKS 759
+ ++ QES +++ S
Sbjct: 33284 SAQSMSSMQESFVEMSSSS 33302
Score = 30.4 bits (67), Expect = 9.6
Identities = 51/247 (20%), Positives = 90/247 (36%), Gaps = 30/247 (12%)
Query: 107 PVKAPPAPP-------PPPPEVIPEPEVSTQPPPEEPGCGSETV-----PVPDGPRSDS- 153
P K PP P P PP + + +++ Q P V P P RS S
Sbjct: 250 PHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPVRSVSP 309
Query: 154 ---VEGSP---------FRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPR 201
+ SP R S A E P Y E+ +T T +
Sbjct: 310 AARISTSPIRSVRSPLLMRKTQASTVATGPEVPPPWKQEGYVASSSEAEMRETTLTTSTQ 369
Query: 202 ASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYST 261
+ EG+ + + T S + + S+S AS A ++G E A + +
Sbjct: 370 IRTEERWEGRYGVQEQVTIS---GAAGAAASVSASASYAAEAVATGAKEVKQDADKSAAV 426
Query: 262 GSSSASSTLKRTKKPRPPSLKK--KQTTKKPTETPPVKETQQEPDEESLVPSGENLASET 319
+ A+ + R ++P ++++ ++TT P +E ++ E++ V A +
Sbjct: 427 ATVVAAVDMARVREPVISAVEQTAQRTTTTAVHIQPAQEQVRKEAEKTAVTKVVVAADKA 486
Query: 320 KTESAKT 326
K + K+
Sbjct: 487 KEQELKS 493
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 70.5 bits (171), Expect = 8e-12
Identities = 146/620 (23%), Positives = 206/620 (33%), Gaps = 124/620 (20%)
Query: 11 QRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPADLESPTL 70
QR S SA P + + TP +P H S P + Q P + P
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAH---PSQPKPKGL-QALRPPQVTPPRK 290
Query: 71 AASSYHGDVVGQVSTDLIAQRSSDSEEAFETP---ESTTPVKA--PPAPP--------PP 117
A+ +G +S+ +A S +A P + TP+ A PP+PP PP
Sbjct: 291 DAAP----ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPP 346
Query: 118 PPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSA--VFDEDKP 175
P P + PP P ++ P S++ P HS ++ + P
Sbjct: 347 SPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406
Query: 176 IASSG---TYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKST--DSVPISKS-TL 229
+A S T +L ++ +F T+ PR + A +R ST DS P+ +L
Sbjct: 407 LALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSP---SRPASTPPDSPPLQAPLSL 463
Query: 230 SRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKK 289
S LQ S S +P + S S S + L + PP +
Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPL--SSLIMPPLETQSSLAPP 521
Query: 290 PTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAAC 349
+TPP T P ENL S P ETP PA C
Sbjct: 522 SLQTPPASLT---------TPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA-----PC 567
Query: 350 PLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSV 409
PL + + PP + PP + P +P P +GL
Sbjct: 568 PLQAPPSPLTTPPPETPSSIATPPP---QAPPALASP----------------PLQGLP- 607
Query: 410 RLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSP- 468
+PP + P A L P ++ P + PASPP SP
Sbjct: 608 ------------------SPPLSPLATPPPQAPPXLALPPLQAPP----SPPASPPLSPL 645
Query: 469 AEPN-DIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPF 527
A P+ P A + PFS P P Q+ PF
Sbjct: 646 ATPSPQAPNALAVHLLQA---------PFSPP------PSPPVQA-------------PF 677
Query: 528 KTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSP 587
+ P SPS +P S P+ A V + PA +P T + P
Sbjct: 678 SPPASPPVSPSATPPSQAPPSLAAPPLQVPP---SPPASPPMSPSATPPPQAPPPLAAPP 734
Query: 588 LSDPPSQDPTPAATPE-TPP 606
L PPS +P +P TPP
Sbjct: 735 LQVPPSPPASPPMSPSATPP 754
Score = 58.5 bits (140), Expect = 3e-08
Identities = 146/662 (22%), Positives = 217/662 (32%), Gaps = 92/662 (13%)
Query: 16 AQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPADLESPTLAASSY 75
A P SA G +++ ++ P AS + +P + SP A+ +
Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPP---ASGRGERAPPAKNTSPGPVSSPGRASGTT 124
Query: 76 HGDVVGQVSTDLIAQRSSDSEEAFETP-----------ESTTPVKAPPAP---------- 114
+GQ + A+ + +A E P +++ P P+P
Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
Query: 115 -----PPPPPEVIPEPEVSTQPPPEEPGCGSE---TVPVPDGPRSDSVEGSPFRPPSHSF 166
P P P P P T+ P + SE T P P R S G RP S S
Sbjct: 185 TEVGLPRPAPSARPRPP--TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
Query: 167 SAVFDEDKPIASSGTYNLDFDN------------IELVDTFQTLEPRASDAKNQEGKVNT 214
S+ A SG ++ + Q PR DA G +++
Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR-KDAAPALGPLSS 301
Query: 215 RRKSTDSVPISKS---------------TLSRSLSLQASDFDGASSSGNPEAVALAPDAY 259
+T S +K+ TL S L S P ++ P
Sbjct: 302 SPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP 361
Query: 260 STGSSSASSTLKRTKKPRPPSLKKKQTTKKPTE-TPPVKETQQEPDEESLVPSGENLASE 318
+T S A ++ PPSL+ + P T P + P S + + +L S
Sbjct: 362 ATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSP 421
Query: 319 T--KTESAKTEGPSPALLEET-PLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPV 375
T T S T P T P PA P + PL + + PP + SP V
Sbjct: 422 TLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL----QTSLSPAV 477
Query: 376 GRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPP---T 432
+ PLT P + S SP LS + S + PP T
Sbjct: 478 SPLSSPLTIHP-----LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT 532
Query: 433 KKIGKKP-VAKMPLRRPKMKKTPEKLDNTPASPP---RSPAEPNDIPIAKGTYTFDIDKW 488
+ P +A PL+ T L+ P P ++P P P + +
Sbjct: 533 PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP- 591
Query: 489 DDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDE--SVDPFKTSSKTPSSPSKSPASFEI 546
P P ++ +Q P P P ++ P + P+SP SP +
Sbjct: 592 --PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPS 649
Query: 547 PASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATP--ET 604
P + N + L P +P F SP SP + PPSQ P A P +
Sbjct: 650 PQAP---NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 706
Query: 605 PP 606
PP
Sbjct: 707 PP 708
Score = 52.0 bits (123), Expect = 3e-06
Identities = 127/592 (21%), Positives = 186/592 (31%), Gaps = 96/592 (16%)
Query: 98 AFETPESTTP---VKAPPAPPPPPPEVIPEP--------EVSTQPPPEEP-GCGSETVPV 145
A TP + P PP P PPP V P V +P E G G T+P
Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72
Query: 146 ------PDGPRSDSVEGSPFRPPS-----HSFSAVFDEDKPIASSGTYN-------LDFD 187
P S RPP+ + A P++S G + L
Sbjct: 73 SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 132
Query: 188 NIELVDTFQTLEPRASDA-KNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDG---A 243
+ + +A++A K RR ++ P + S S A G
Sbjct: 133 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 192
Query: 244 SSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPS----LKKKQTTKKPTETPPVKET 299
+ S P P + +S S+T R PS L++ + + P+
Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 252
Query: 300 QQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGV 359
+ P S+ K + + P PA+GP ++ PL + S G
Sbjct: 253 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGT 312
Query: 360 ----VPPASGG-----GRVQNSPPVGRKTLPLT-----------TAPEAGEVTPSDSGGQ 399
VPP + SPP+ LPL T P PS +
Sbjct: 313 KARPVPPPDNAATPLPATLPPSPPLA-TPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371
Query: 400 EDSPAKGLSVRLE-FDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLD 458
+P L+ + S + PP+ A L P ++ T L
Sbjct: 372 MTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLT 431
Query: 459 NTP-------ASPPRSPAEPNDIPIAKGTYTF----DIDKWDDPNFNPFSS--------- 498
+P SP R + P D P + + + P +P SS
Sbjct: 432 MSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQA 491
Query: 499 -TSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVD 557
+S SP+ P S P S+ P S +TP + +P +P+ A
Sbjct: 492 LSSLASHSPQAPLSSLIMPPLETQSSLAP--PSLQTPPASLTTPPLENLPSLA------- 542
Query: 558 GDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVIS 609
P + PL T P PL PPS TP PETP I+
Sbjct: 543 ----PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP--PPETPSSIA 588
Score = 48.1 bits (113), Expect = 4e-05
Identities = 87/390 (22%), Positives = 119/390 (30%), Gaps = 35/390 (8%)
Query: 18 TPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPADLESPTLAASSYHG 77
TP P + ++ + P SP + S P + + A P P+LAA
Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 706
Query: 78 DVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPG 137
S + S A P++ P+ APP PP P P S PPP P
Sbjct: 707 PPSPPASPPM-------SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759
Query: 138 -CGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQ 196
+ + VP P + +PP + A+ S +
Sbjct: 760 LLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 819
Query: 197 TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAP 256
+ P A+ + P + TL D S SG +ALAP
Sbjct: 820 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD-TSVSGPRLTLALAP 878
Query: 257 DAYSTGSSSASSTLKRTKKPRPPSL--KKKQTTKKPTETPPVKETQQEPDEESLVPSGEN 314
S S SSTL P L T P E + S P E
Sbjct: 879 GPPPPPSRSPSSTLS------GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 932
Query: 315 LASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPP 374
A +A + GP+P PL P A P PPA+G G
Sbjct: 933 AACH---PAAWSRGPAP------PLAFRGAPGAPLPW---------PPATGPGSADGLCT 974
Query: 375 VGRKTLPLTTAPEAGEVTPSDSGGQEDSPA 404
+ P + P G + P S G A
Sbjct: 975 IYETEGPESATPAPGALDPGPSPGTSGGKA 1004
Score = 38.1 bits (87), Expect = 0.046
Identities = 41/160 (25%), Positives = 60/160 (37%), Gaps = 17/160 (10%)
Query: 17 QTPRS--AQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAA-PADLESPTLAAS 73
Q P S A PP + Q P + SP A + P+A P P LAA
Sbjct: 705 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAP 764
Query: 74 SYHGDVVGQVSTDL--IAQRSSDSEEAFETPESTTPVKAPPAPPPP--------PPEVIP 123
S + +A+ + A TP P++A P+PP P +P
Sbjct: 765 PLQVPPSPPASLPMSPLAKPPPQAPPALATP----PLQALPSPPASFPGQAPFSPSASLP 820
Query: 124 EPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPS 163
++T PP P + + VP P + +P RPP+
Sbjct: 821 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 860
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 67.4 bits (163), Expect = 7e-11
Identities = 104/446 (23%), Positives = 165/446 (36%), Gaps = 56/446 (12%)
Query: 249 PEAVALAPDAYSTGSSSASSTLKR----TKKPRPPSLKKKQTTKKPT---ETPPV----- 296
PE ++P + STG S + + TKKP K TT+KPT E P +
Sbjct: 540 PELPPVSPVS-STGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKP 598
Query: 297 ----------KETQQEPDEESLVPSGEN--LASETKTESAKTEGPS--PALLEETPLEPA 342
E P E+ +PS + L + S K PS P + E P P
Sbjct: 599 TISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPT 658
Query: 343 VGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDS 402
P + S E V P + S P + ++P + E T + S
Sbjct: 659 EEPTTPTEETTTSMEEPVIPTE-----KPSIPTEKPSIPTEKPTISMEETIISTEKPTIS 713
Query: 403 PAKGLSVRLEFDYSEDKSSWDNQQENPP---PTKKIGKKPVAKMPLRRPKMKKT--PEKL 457
P K + +KS+ ++ P PT K ++ P K T PEKL
Sbjct: 714 PEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKL 773
Query: 458 DNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDP 517
P P P E IP K T + ++P P T+ E P +P +
Sbjct: 774 -TIPTEKPTIPTEKPTIPTEKPTIS-----TEEPT-TPTEETTISTEKPSIPMEKPTLPT 826
Query: 518 DTCDESVDPFKTSSKTPSSPSKSPA-SFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDT 576
+ SV+ S++ + P + P S E P E + + L P +K P + T
Sbjct: 827 EETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPT 886
Query: 577 FRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEA 636
++++ + P++ PT +PE P + EK + +K T T +
Sbjct: 887 IPIEETTISTEKLTIPTEKPT--ISPEKPTI--------STEKPTIPTEKPTIPTEETTI 936
Query: 637 DKQDYPQPSDLSTFVNETKFSSPTEE 662
+ P++ T ++ K + PTE+
Sbjct: 937 STEKLTIPTEKPT-ISPEKLTIPTEK 961
Score = 42.4 bits (98), Expect = 0.002
Identities = 65/320 (20%), Positives = 117/320 (36%), Gaps = 40/320 (12%)
Query: 491 PNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPA-SFEIPAS 549
P +P SST + + + + T S++ +++ P+ P + P E P
Sbjct: 543 PPVSPVSSTGPSETTGLTENPTISTKKPTV--SIEKPSVTTEKPTVPKEKPTIPTEKPTI 600
Query: 550 AMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPT--------PAAT 601
+ E + + N P++K P + T +K S PS+ PT P
Sbjct: 601 STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE 660
Query: 602 PETP----------PVISAVVHATDEEKLAVTNQKWTCMTVD---------LEADKQDYP 642
P TP PVI + EK ++ +K T + + +K P
Sbjct: 661 PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP 720
Query: 643 Q-----PSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMF 697
P++ ST ++ K ++PTE+ EK + + +P+K L
Sbjct: 721 TEKPTIPTEKST-ISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEK----LTI 775
Query: 698 DTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQVPE 757
T + + P +E PT + TE + K P+ + P +E+ V E
Sbjct: 776 PTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEE 835
Query: 758 KSSQKELEAMGLGTPSEAIE 777
+ E + + P+ + E
Sbjct: 836 TTISTEKLTIPMEKPTISTE 855
Score = 36.6 bits (83), Expect = 0.13
Identities = 82/414 (19%), Positives = 138/414 (33%), Gaps = 79/414 (19%)
Query: 101 TPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFR 160
T + T P + P P + EP + P E+P +E +P + S+E
Sbjct: 651 TEKPTVPTEEPTTPTEETTTSMEEPVI----PTEKPSIPTEKPSIPTEKPTISME----- 701
Query: 161 PPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTD 220
+ +KP S + + + T+ P ++ + T + +
Sbjct: 702 ------ETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTIS 755
Query: 221 ----SVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 276
+ P K T+S PE + + + + T+KP
Sbjct: 756 PEKPTTPTEKPTIS------------------PEKLTIPTEKPTI----------PTEKP 787
Query: 277 RPPSLKKKQTTKKPT----ETPPVKETQQEPDEESLVPSGENLAS--ETKTESAKTEGP- 329
P+ K +T++PT ET E P E+ +P+ E S ET + K P
Sbjct: 788 TIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPM 847
Query: 330 -SPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEA 388
P + E P P P + S E + P + + P + T+P+ +
Sbjct: 848 EKPTISTEKPTIPTEKP-------TISPEKLTIPTE-----KLTIPTEKPTIPIEETTIS 895
Query: 389 GEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRP 448
E + SP K S +K + ++ P + +P +P
Sbjct: 896 TEKLTIPTEKPTISPEKP-------TISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKP 948
Query: 449 KMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKM 502
+ +PEKL P P E IP K T +K P P T K+
Sbjct: 949 TI--SPEKL-TIPTEKPTISTEKPTIPTEK--LTIPTEKPTIPTEKPTIPTEKL 997
Score = 34.3 bits (77), Expect = 0.66
Identities = 54/290 (18%), Positives = 104/290 (35%), Gaps = 36/290 (12%)
Query: 95 SEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSV 154
+E++ +PE T P P P + PE + P E+P E + +P +
Sbjct: 728 TEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTT---PTEKPTISPEKLTIPTEKPTIPT 784
Query: 155 EGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNT 214
E +P + ++P + + + + TL + +E ++T
Sbjct: 785 E----KPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST 840
Query: 215 RRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKR-- 272
+ ++P+ K T +S + + +PE + + + + + + ++
Sbjct: 841 EKL---TIPMEKPT----ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETT 893
Query: 273 ---------TKKPRPPSLKKKQTTKKPT-----ETPPVKETQQEPDE-----ESLVPSGE 313
T+KP K +T+KPT T P +ET ++ E S E
Sbjct: 894 ISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPE 953
Query: 314 NLASETKTESAKTEGPS-PALLEETPLEPAVGPKAACPLDSESAEGVVPP 362
L T+ + TE P+ P P E P + +E + PP
Sbjct: 954 KLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPP 1003
Score = 30.8 bits (68), Expect = 7.3
Identities = 53/271 (19%), Positives = 94/271 (34%), Gaps = 36/271 (13%)
Query: 100 ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPF 159
ET ST P P P E P + PE+P +E +P ++ SP
Sbjct: 702 ETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIP----TEKPTISPE 757
Query: 160 RPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKST 219
+P + + +KP S + + + T+ ++ ++T +T
Sbjct: 758 KPTTPT-------EKPTISP-------EKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTT 803
Query: 220 DSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPP 279
+ + ST S+ ++ ++ + E ++ + + + + T+KP P
Sbjct: 804 PTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTIS---TEKPTIP 860
Query: 280 SLKKKQTTKKPTETPPVKETQQE----PDEESLVPSGENLASETK----TESAKTEGPSP 331
T+KPT +P E P E+ +P E S K TE P
Sbjct: 861 -------TEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKP 913
Query: 332 ALLEETPLEPAVGPKAACPLDSESAEGVVPP 362
+ E P P P + S E + P
Sbjct: 914 TISTEKPTIPTEKPTIPTEETTISTEKLTIP 944
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 67.4 bits (163), Expect = 7e-11
Identities = 104/446 (23%), Positives = 165/446 (36%), Gaps = 56/446 (12%)
Query: 249 PEAVALAPDAYSTGSSSASSTLKR----TKKPRPPSLKKKQTTKKPT---ETPPV----- 296
PE ++P + STG S + + TKKP K TT+KPT E P +
Sbjct: 540 PELPPVSPVS-STGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKP 598
Query: 297 ----------KETQQEPDEESLVPSGEN--LASETKTESAKTEGPS--PALLEETPLEPA 342
E P E+ +PS + L + S K PS P + E P P
Sbjct: 599 TISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPT 658
Query: 343 VGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDS 402
P + S E V P + S P + ++P + E T + S
Sbjct: 659 EEPTTPTEETTTSMEEPVIPTE-----KPSIPTEKPSIPTEKPTISMEETIISTEKPTIS 713
Query: 403 PAKGLSVRLEFDYSEDKSSWDNQQENPP---PTKKIGKKPVAKMPLRRPKMKKT--PEKL 457
P K + +KS+ ++ P PT K ++ P K T PEKL
Sbjct: 714 PEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKL 773
Query: 458 DNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDP 517
P P P E IP K T + ++P P T+ E P +P +
Sbjct: 774 -TIPTEKPTIPTEKPTIPTEKPTIS-----TEEPT-TPTEETTISTEKPSIPMEKPTLPT 826
Query: 518 DTCDESVDPFKTSSKTPSSPSKSPA-SFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDT 576
+ SV+ S++ + P + P S E P E + + L P +K P + T
Sbjct: 827 EETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPT 886
Query: 577 FRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEA 636
++++ + P++ PT +PE P + EK + +K T T +
Sbjct: 887 IPIEETTISTEKLTIPTEKPT--ISPEKPTI--------STEKPTIPTEKPTIPTEETTI 936
Query: 637 DKQDYPQPSDLSTFVNETKFSSPTEE 662
+ P++ T ++ K + PTE+
Sbjct: 937 STEKLTIPTEKPT-ISPEKLTIPTEK 961
Score = 42.4 bits (98), Expect = 0.002
Identities = 65/320 (20%), Positives = 117/320 (36%), Gaps = 40/320 (12%)
Query: 491 PNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPA-SFEIPAS 549
P +P SST + + + + T S++ +++ P+ P + P E P
Sbjct: 543 PPVSPVSSTGPSETTGLTENPTISTKKPTV--SIEKPSVTTEKPTVPKEKPTIPTEKPTI 600
Query: 550 AMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPT--------PAAT 601
+ E + + N P++K P + T +K S PS+ PT P
Sbjct: 601 STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE 660
Query: 602 PETP----------PVISAVVHATDEEKLAVTNQKWTCMTVD---------LEADKQDYP 642
P TP PVI + EK ++ +K T + + +K P
Sbjct: 661 PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP 720
Query: 643 Q-----PSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMF 697
P++ ST ++ K ++PTE+ EK + + +P+K L
Sbjct: 721 TEKPTIPTEKST-ISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEK----LTI 775
Query: 698 DTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQVPE 757
T + + P +E PT + TE + K P+ + P +E+ V E
Sbjct: 776 PTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEE 835
Query: 758 KSSQKELEAMGLGTPSEAIE 777
+ E + + P+ + E
Sbjct: 836 TTISTEKLTIPMEKPTISTE 855
Score = 36.6 bits (83), Expect = 0.13
Identities = 82/414 (19%), Positives = 138/414 (33%), Gaps = 79/414 (19%)
Query: 101 TPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFR 160
T + T P + P P + EP + P E+P +E +P + S+E
Sbjct: 651 TEKPTVPTEEPTTPTEETTTSMEEPVI----PTEKPSIPTEKPSIPTEKPTISME----- 701
Query: 161 PPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTD 220
+ +KP S + + + T+ P ++ + T + +
Sbjct: 702 ------ETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTIS 755
Query: 221 ----SVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 276
+ P K T+S PE + + + + T+KP
Sbjct: 756 PEKPTTPTEKPTIS------------------PEKLTIPTEKPTI----------PTEKP 787
Query: 277 RPPSLKKKQTTKKPT----ETPPVKETQQEPDEESLVPSGENLAS--ETKTESAKTEGP- 329
P+ K +T++PT ET E P E+ +P+ E S ET + K P
Sbjct: 788 TIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPM 847
Query: 330 -SPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEA 388
P + E P P P + S E + P + + P + T+P+ +
Sbjct: 848 EKPTISTEKPTIPTEKP-------TISPEKLTIPTE-----KLTIPTEKPTIPIEETTIS 895
Query: 389 GEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRP 448
E + SP K S +K + ++ P + +P +P
Sbjct: 896 TEKLTIPTEKPTISPEKP-------TISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKP 948
Query: 449 KMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKM 502
+ +PEKL P P E IP K T +K P P T K+
Sbjct: 949 TI--SPEKL-TIPTEKPTISTEKPTIPTEK--LTIPTEKPTIPTEKPTIPTEKL 997
Score = 34.3 bits (77), Expect = 0.66
Identities = 54/290 (18%), Positives = 104/290 (35%), Gaps = 36/290 (12%)
Query: 95 SEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSV 154
+E++ +PE T P P P + PE + P E+P E + +P +
Sbjct: 728 TEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTT---PTEKPTISPEKLTIPTEKPTIPT 784
Query: 155 EGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNT 214
E +P + ++P + + + + TL + +E ++T
Sbjct: 785 E----KPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST 840
Query: 215 RRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKR-- 272
+ ++P+ K T +S + + +PE + + + + + + ++
Sbjct: 841 EKL---TIPMEKPT----ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETT 893
Query: 273 ---------TKKPRPPSLKKKQTTKKPT-----ETPPVKETQQEPDE-----ESLVPSGE 313
T+KP K +T+KPT T P +ET ++ E S E
Sbjct: 894 ISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPE 953
Query: 314 NLASETKTESAKTEGPS-PALLEETPLEPAVGPKAACPLDSESAEGVVPP 362
L T+ + TE P+ P P E P + +E + PP
Sbjct: 954 KLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPP 1003
Score = 30.8 bits (68), Expect = 7.3
Identities = 53/271 (19%), Positives = 94/271 (34%), Gaps = 36/271 (13%)
Query: 100 ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPF 159
ET ST P P P E P + PE+P +E +P ++ SP
Sbjct: 702 ETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIP----TEKPTISPE 757
Query: 160 RPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKST 219
+P + + +KP S + + + T+ ++ ++T +T
Sbjct: 758 KPTTPT-------EKPTISP-------EKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTT 803
Query: 220 DSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPP 279
+ + ST S+ ++ ++ + E ++ + + + + T+KP P
Sbjct: 804 PTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTIS---TEKPTIP 860
Query: 280 SLKKKQTTKKPTETPPVKETQQE----PDEESLVPSGENLASETK----TESAKTEGPSP 331
T+KPT +P E P E+ +P E S K TE P
Sbjct: 861 -------TEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKP 913
Query: 332 ALLEETPLEPAVGPKAACPLDSESAEGVVPP 362
+ E P P P + S E + P
Sbjct: 914 TISTEKPTIPTEKPTIPTEETTISTEKLTIP 944
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 66.6 bits (161), Expect = 1e-10
Identities = 168/748 (22%), Positives = 263/748 (35%), Gaps = 105/748 (14%)
Query: 80 VGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVS-TQPPPEE--- 135
+G+ L Q + E E P P ++P +PPP P PE S PPPEE
Sbjct: 419 LGKAGVQLEPQLEAPLNE--EMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPA 476
Query: 136 ---PGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELV 192
P + P+ + P S E SP PP S E+ P++ + +
Sbjct: 477 SPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPE----ESPPSPAL 532
Query: 193 DTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAV 252
+T + P AS S P +S LS + +S PEA
Sbjct: 533 ETPLSPPPEASPL---------------SPPFEESPLS-------PPPEELPTSPPPEAS 570
Query: 253 ALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLV--P 310
L+P + S + P L + P PP + P E S + P
Sbjct: 571 RLSPPPEESPMSPPPEESPMSPPPEASRL-FPPFEESPLSPPPEESPLSPPPEASRLSPP 629
Query: 311 SGENLASETKTESAKTEGPSPALLEETPLEPAVG-PKAACPLDSESAEGVVPPASGGGRV 369
++ S ES + P + L P+ + P PL E P R+
Sbjct: 630 PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRL 689
Query: 370 QNSPPVGRKTLPLTTAPEAGEVTPSDSGG-----QEDSPAKGLSVRLEFDYSEDKSSWDN 424
SPP + P + PE +P E+SP L + +
Sbjct: 690 --SPP--PEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSP 745
Query: 425 QQENP---PPTKKIGKKPVAKMPLRRPKMKK-----TPEKLDNTP-ASPPRSPAEPNDIP 475
+ E P P ++ P A+ P P+ ++ PE+ +P A P +P ++
Sbjct: 746 RPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH 805
Query: 476 IAKGTYTFDIDKW-DDPNFNP---FSSTSKMQESPKL---PQQSYNFDPDTCDESVDPFK 528
++ T + ++P +P S S E P L P++S+ P+ + P
Sbjct: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESH-LSPELEKPPLSP-- 862
Query: 529 TSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKK--KTPLKTDTFRVKKSPKRS 586
K P P + PA E+P L +PA + + PL + SP
Sbjct: 863 RPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGE 922
Query: 587 PLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLE---ADKQDYPQ 643
P P P P PP +S ++ A L+ +LE K D
Sbjct: 923 PSLSPQLMPPDP-----LPPPLSPIITAAAPPALSPLG--------ELEYPFGAKGDSDP 969
Query: 644 PSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFD--TSQ 701
S L+ + ET S P E N + E + + LP +P A ++ + Q
Sbjct: 970 ESPLAAPILETPISPPPE----ANCTDPEPVPPM--ILPPSPGSPVGPASPILMEPLPPQ 1023
Query: 702 ESP-VKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPR--GLAPNQESHLQVPEK 758
SP ++ S V + P+ CS AL + P+ + G++ E H EK
Sbjct: 1024 CSPLLQHSLVPQNSPPSQCS------PPALPLSVPSPLSPIGKVVGVSDEAELHEMETEK 1077
Query: 759 SSQKELEAMGLGTPSEAIEITAPEGSFA 786
S+ E A+ PS + +P G +
Sbjct: 1078 VSEPECPAL---EPSATSPLPSPMGDLS 1102
Score = 58.5 bits (140), Expect = 3e-08
Identities = 145/651 (22%), Positives = 222/651 (34%), Gaps = 108/651 (16%)
Query: 22 AQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPADLESPTLAASSYHGDVVG 81
A P + ++ R +++P SP ++ SP + P +P + ESP
Sbjct: 476 ASPLPEALHLSRPLEESPLSPPPEESPLSPPPES--SPFSPLE-ESPLSPPEESPPSPAL 532
Query: 82 QVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVS-TQPPPEE----- 135
+ + S S E+P S P + P +PPP + P PE S PPPEE
Sbjct: 533 ETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP 592
Query: 136 -PGCGSETVPVPDGPRSDSVEGSPFRPPSH-SFSAVFDEDKPIA-----SSGTYNLDFDN 188
P P + P S E SP PP S + ED P++ S + +
Sbjct: 593 PPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR 652
Query: 189 IELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLS------------------ 230
+ + L P ++ +S S P S LS
Sbjct: 653 LSPLPVVSRLSPPPEESPLSP----PPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPAS 708
Query: 231 --RSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTK 288
SL + + + PE L P + S + +P P L +
Sbjct: 709 PPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEP 768
Query: 289 KPTETPPVKETQQEPDEESLVPSGENLASETKTE----SAKTEGPSPALLEETPLEPAVG 344
+ P P+E L P E + E S +TE P L P EP +
Sbjct: 769 HLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPH---LSPVPEEPCLS 825
Query: 345 PK-AACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSP 403
P+ L +S E + P + SP + + PL+ PE P E+ P
Sbjct: 826 PQPEESHLSPQSEEPCLSPRPEESHL--SPELEKP--PLSPRPEKPPEEPGQCPAPEELP 881
Query: 404 AKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRP-----KMKKTPEKLD 458
F + S + P + G+ P++ +P P + +P+ +
Sbjct: 882 L--------FPPPGEPSL--SPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMP 931
Query: 459 NTPASPPRSP-----AEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSY 513
P PP SP A P P+ + Y F DP +P + + + E+P P
Sbjct: 932 PDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPE-SPLA--APILETPISPPPEA 988
Query: 514 N-FDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 572
N DP+ + P SP S PAS + L +P + +PL
Sbjct: 989 NCTDPEPVPPMILP------------PSPGSPVGPASPI---------LMEPLPPQCSPL 1027
Query: 573 KTDTFRVKKSPKRSPLSDPPSQDPTPA---ATPETPPVISAVVHATDEEKL 620
+ P + PPSQ PA + P I VV +DE +L
Sbjct: 1028 LQHSL--------VPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAEL 1070
Score = 36.6 bits (83), Expect = 0.13
Identities = 74/334 (22%), Positives = 115/334 (34%), Gaps = 52/334 (15%)
Query: 505 SPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKP 564
SP P + +PD + S K P + A + GV + +
Sbjct: 373 SPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEA 432
Query: 565 AKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTN 624
++ PL P+ SPLS PP + PT +PP ++ + EE A
Sbjct: 433 PLNEEMPLLPP-------PEESPLSPPPEESPT------SPPPEASRLSPPPEELPA--- 476
Query: 625 QKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSS-LPQ 683
P+ LS + E+ S P EE E + S L
Sbjct: 477 --------------SPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSP 522
Query: 684 DDDAPKKQALYL----------MFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNT 733
+++P AL + +ESP+ P + SP P + E +
Sbjct: 523 PEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMS 582
Query: 734 AAKNQHPV------PRGLAPNQESHLQVPEKSS--QKELEAMGLGTPSEAIEIT-APEGS 784
+ P+ R P +ES L P + S EA L P E ++ PE S
Sbjct: 583 PPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEES 642
Query: 785 FASADALLSRLAHPVSLCGALDYLEPDLAEKNPP 818
S +SRL+ P+ + L P+ + +PP
Sbjct: 643 PMSPPPEVSRLS-PLPVVSRLS-PPPEESPLSPP 674
Score = 36.6 bits (83), Expect = 0.13
Identities = 84/359 (23%), Positives = 114/359 (31%), Gaps = 56/359 (15%)
Query: 37 DTPGSPDHRDASSSPVADDIIQPAA-PADLESPTL-----AASSYHGDVVGQVSTDLIAQ 90
+ P SP + SP + + P P D P L AA+ +G++ A+
Sbjct: 905 EPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAK 964
Query: 91 RSSDSEEAFETPESTTPVKAPPA-----PPPPPPEVIPEPEVSTQPP-------PEEPGC 138
SD E P TP+ PP P P PP ++P S P P P C
Sbjct: 965 GDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQC 1024
Query: 139 G----SETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIEL--V 192
VP P S P PS P++ G D EL +
Sbjct: 1025 SPLLQHSLVPQNSPPSQCSPPALPLSVPS-----------PLSPIGKVVGVSDEAELHEM 1073
Query: 193 DTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAV 252
+T + EP + +T +P LS A D S G A
Sbjct: 1074 ETEKVSEPECPALE---------PSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAP 1124
Query: 253 ALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSG 312
DA GS +T LK P E PV T E E +G
Sbjct: 1125 LDGIDA--PGSQPEPG---QTPGSLASELKGSPVLLDPEELAPV--TPMEVYPECKQTAG 1177
Query: 313 ENLASETKTESAKTEGPSPALLEETPLEPAV-----GPKAACPLDSESAEGVVPPASGG 366
+ E + E P+P L ++ + + G +A SE G P GG
Sbjct: 1178 QGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGG 1236
Score = 32.3 bits (72), Expect = 2.5
Identities = 22/69 (31%), Positives = 28/69 (40%), Gaps = 10/69 (14%)
Query: 102 PESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRS--------DS 153
PE +P +P AP P P P E+ T+P E P +P+ P S
Sbjct: 4911 PEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPV--PSPLPLASSPESARPKPRARPP 4968
Query: 154 VEGSPFRPP 162
EG RPP
Sbjct: 4969 EEGEDSRPP 4977
Score = 30.8 bits (68), Expect = 7.3
Identities = 29/122 (23%), Positives = 40/122 (32%), Gaps = 1/122 (0%)
Query: 276 PRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPS-GENLASETKTESAKTEGPSPALL 334
P PP P P + QEP S +PS L +E + P P
Sbjct: 4290 PAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGP 4349
Query: 335 EETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPS 394
P V P AA D+ ++G+ P + P +P G+V P
Sbjct: 4350 TLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPE 4409
Query: 395 DS 396
S
Sbjct: 4410 AS 4411
Score = 30.8 bits (68), Expect = 7.3
Identities = 87/392 (22%), Positives = 139/392 (35%), Gaps = 90/392 (22%)
Query: 104 STTPVKAPPAPPPPPPEVIPEPE-------------VSTQPPPEEPGCGSETVPVPDGPR 150
ST PV P P PPP EP+ Q PP PG P P GP
Sbjct: 4297 STGPVLGP-VHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPG-----TPKPQGPT 4350
Query: 151 SDSVEG------------------SPFRPPSHSFSAVFDEDKPIASS-GTYNLDFDNIEL 191
+ G P+ PP + + + KP SS +LD N ++
Sbjct: 4351 LEPPPGRVSPAAAQLADTLFSKGLGPWDPPDN----LAETQKPEQSSLVPGHLDQVNGQV 4406
Query: 192 VDTFQTL--------EPRASDAKNQEGKVN--------TRRKSTDSVPISKS-TLSRSLS 234
V L EP A A++ + + N T + P S++ L
Sbjct: 4407 VPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKL 4466
Query: 235 LQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETP 294
L+A + ++ G+ A + + L+ T + + +K T KP
Sbjct: 4467 LRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQ 4526
Query: 295 PVKE----TQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACP 350
+ ++++ +E V + E L + K E + PA+ L G + CP
Sbjct: 4527 KASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFG--SGCP 4584
Query: 351 LDSESAEGVVPPASGGGRVQ---------------NSPPVGRKTLPLTTAPEAGE----- 390
++ +S + A G G + ++PP +LP T P +
Sbjct: 4585 VNGQSQ---LRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNG 4641
Query: 391 VTPSDSGGQ--EDSPAKGLSVRLEFDYSEDKS 420
VTPS+ G+ +D+ + S R D SE KS
Sbjct: 4642 VTPSEELGEHPKDAASARDSERALRDTSEVKS 4673
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 66.6 bits (161), Expect = 1e-10
Identities = 137/625 (21%), Positives = 219/625 (35%), Gaps = 106/625 (16%)
Query: 4 ENSTSDNQRTLSAQT--PRSAQPPGNSQNIKRKQQDTPG-SPDHRDASSSPVADDIIQPA 60
E+S +R+ S + RS P S ++R+++ + SP HR S SP PA
Sbjct: 160 ESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSP------SPA 213
Query: 61 APADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPE 120
++P L S E + + ST+ + P P P P
Sbjct: 214 PEKKEKTPELPEPSV-----------------KVKEPSVQEATSTSDILKVPKPEPIPEP 256
Query: 121 VIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSG 180
P PE +++ E+ E RS S + R PSH+ +P
Sbjct: 257 KEPSPEKNSKKEKEK-----EKTRPRSRSRSKSRSRTRSRSPSHT--------RPRRRHR 303
Query: 181 TYNLDFDNIELVDTFQTLEPRASDA----------KNQEGKVNTRRKSTDSVPISKSTLS 230
+ + + + PR + V RR+S+ S+ S S+ S
Sbjct: 304 SRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSS 363
Query: 231 RSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKP 290
S S S P +P + S ++S +R +P PP+ +T P
Sbjct: 364 SSRS--------RSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSP 415
Query: 291 TETPPVKETQQEPDEESLVPSGENLASETKTE-SAKTEGPSPALLEETPLEPAVGPKAAC 349
T P + + S+ P G TK + + K E PSPA PK
Sbjct: 416 T---PQQSNRTRKSRVSVSP-GRTSGKVTKHKGTEKRESPSPA------------PKPRK 459
Query: 350 PLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSV 409
SES E + VQ R+ ++ ++G + S+ + S K V
Sbjct: 460 VELSESEEDKGGKMAAADSVQQRRQYRRQN--QQSSSDSGSSSSSEDERPKRSHVKNGEV 517
Query: 410 RLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPA 469
+S +S+ +P P K+ + R P T + +PA PPR
Sbjct: 518 GRRRRHSPSRSA------SPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRR 571
Query: 470 EPNDIPIAKGTYTFDIDKWDDPNFNP-FSSTSKMQESPKLPQQSYNFDPDTCDESVDPFK 528
P P + P+ P S S + SP + Q+ Y+ P P K
Sbjct: 572 TPTPPPRRR-----------TPSPPPRRRSPSPRRYSPPI-QRRYSPSP--------PPK 611
Query: 529 TSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRS-- 586
+ +P P K AS P ++ + P K+++P + R SP RS
Sbjct: 612 RRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTR 671
Query: 587 -PLSDPPSQDPTPAATPETPPVISA 610
S P++ +P+ P P S+
Sbjct: 672 EARSPQPNKRHSPSPRPRAPQTSSS 696
Score = 57.8 bits (138), Expect = 6e-08
Identities = 122/567 (21%), Positives = 193/567 (34%), Gaps = 86/567 (15%)
Query: 93 SDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSD 152
S S + + S +P K PP PP S PP P P S
Sbjct: 356 SGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSP 415
Query: 153 SVEGS-PFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGK 211
+ + S R S S K GT + + +PR + E
Sbjct: 416 TPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPS-------PAPKPRKVELSESEED 468
Query: 212 VNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALA---------PDAYSTG 262
+ + DSV + R + Q+S G+SSS E + +S
Sbjct: 469 KGGKMAAADSV--QQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPS 526
Query: 263 SSSASSTLKRTKK----------PRPPSLKKKQT-------TKKPTETPPVKETQQEPDE 305
S++ S KR K+ P PP +++++ ++ T TPP + P
Sbjct: 527 RSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPP 586
Query: 306 ESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASG 365
PS + + + PSP T P + A P PP
Sbjct: 587 RRRSPSPRRYSPPIQ----RRYSPSPPPKRRTASPPPPPKRRASP---------SPPPK- 632
Query: 366 GGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQ 425
RV +SPP +++ P+T +PS S + S R E +S N+
Sbjct: 633 -RRVSHSPPPKQRSSPVTK-----RRSPSLSSKHRKGSSPSRSTR------EARSPQPNK 680
Query: 426 QENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPP-----RSPAEPNDIPIAKGT 480
+ +P P + + + P+RR + +P++ P R+P EP I A
Sbjct: 681 RHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTP-EPKKIKKAASP 739
Query: 481 YTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKS 540
+ + S ++ P P + P T P K +K+P +PS S
Sbjct: 740 SPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVK-KAKSP-TPSPS 797
Query: 541 PASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRV-KKSPKRSPLSDPPSQDPTPA 599
P P ++ + +G G K KK K K + KK K ++ + TPA
Sbjct: 798 P-----PRNSDQ----EGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPA 848
Query: 600 ATPETPPVISAVVHATDEEKLAVTNQK 626
A + +A EE +A K
Sbjct: 849 A------IAAATTTLAQEEPVAAPEPK 869
Score = 35.0 bits (79), Expect = 0.39
Identities = 37/159 (23%), Positives = 60/159 (37%), Gaps = 17/159 (10%)
Query: 3 NENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAP 62
+ +S ++ T A++P+ + S + Q + P R ASSSP + +P
Sbjct: 660 HRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQ-----RRQSP 714
Query: 63 ADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAP----PPPP 118
+ P S I + +S S ++ S+ V P P PP P
Sbjct: 715 SPSTRPIRRVSR-------TPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAP 767
Query: 119 PEVIPEPEVSTQPPPEEPGCGSET-VPVPDGPRSDSVEG 156
P + ST P P +++ P P PR+ EG
Sbjct: 768 PSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEG 806
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
Length = 2462
Score = 65.5 bits (158), Expect = 3e-10
Identities = 106/466 (22%), Positives = 164/466 (35%), Gaps = 91/466 (19%)
Query: 29 QNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLI 88
+N +RK++ P + A V D+ ++ + + E + + + S+D
Sbjct: 677 RNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEA----EATVNNSSDTE 732
Query: 89 AQRSSDSEEAFETPESTTPVKA-------PPAPPPPPPEVIPEPEVST---------QPP 132
+ S +E A +T ++ A PP PP PPPE IP P T PP
Sbjct: 733 SIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPP 792
Query: 133 PEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELV 192
P P S + P P P+ + E + PP +E KP A+ V
Sbjct: 793 PAPP---SPSAPPPVVPKEEKEEETAAAPPVEE----GEEQKPPAAEEL---------AV 836
Query: 193 DTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAV 252
DT + EP S+ + + + K ++ + +L+A +G S
Sbjct: 837 DTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEG-----ALKAEKKEGGSGRATTAKS 891
Query: 253 ALAP-DAYSTGSSSASST-------LKRTKKPRP----------------PSLKKKQTTK 288
+ AP D+ S+ + SA R PRP L KQ +
Sbjct: 892 SGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQ 951
Query: 289 KPTETPPVKETQ-QEPDEESLVPSGENLASETKTESAKTEGPSPALLE---ETPLEPAVG 344
+ PP++ T+ EP E P T+ A P P L+ + P +P
Sbjct: 952 RAAAIPPIQVTKVHEPPREDAAP----------TKPAPPAPPPPQNLQPESDAPQQPGSS 1001
Query: 345 PKA-----ACPLDSESAEGVVPP--ASGGGRVQNSPPVGRKTLPLTTAP----EAGEVTP 393
P+ A P D E+ + V P A+ ++ PP LP P +A P
Sbjct: 1002 PRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAP 1061
Query: 394 SDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKP 439
S P L + L D + NPPP K P
Sbjct: 1062 DPSAFSYAPPGHPLPLGLH-DTARPVLPRPPTISNPPPLISSAKHP 1106
Score = 39.3 bits (90), Expect = 0.021
Identities = 53/249 (21%), Positives = 84/249 (33%), Gaps = 32/249 (12%)
Query: 249 PEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESL 308
P P + +TG+ + P PP + K++ ++ PPV+E EE
Sbjct: 774 PAPTEPTPASEATGAPTPPPAPPSPSAP-PPVVPKEEKEEETAAAPPVEE-----GEEQK 827
Query: 309 VPSGENLASET-------KTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVP 361
P+ E LA +T K+E + PA ++ A A E G
Sbjct: 828 PPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRAT 887
Query: 362 PASGGGRVQNSPPVGRKTLPLTTAPEAGE-----------VTPSDSGGQEDSPAKGLSVR 410
A G Q+S + E G+ +TP+ SP K L ++
Sbjct: 888 TAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLK 947
Query: 411 ------LEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASP 464
+ + +E+ PTK P P P++ ++P
Sbjct: 948 QLKQRAAAIPPIQVTKVHEPPREDAAPTKPA--PPAPPPPQNLQPESDAPQQPGSSPRGK 1005
Query: 465 PRSPAEPND 473
RSPA P D
Sbjct: 1006 SRSPAPPAD 1014
Score = 30.8 bits (68), Expect = 7.3
Identities = 42/182 (23%), Positives = 78/182 (42%), Gaps = 29/182 (15%)
Query: 908 EREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMI--EDEQREKSVSHQTVQ---QLVL 962
E EVSE D E +MR++ I M+ D+QR K ++ + V
Sbjct: 369 EHEVSEIIDGLSEQENLEKQMRQLAV-----IPPMLYDADQQRIKFINMNGLMADPMKVY 423
Query: 963 EKEQALADLNSVEK-SLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQ 1021
+ Q + + EK + + F ++ K ++ F + + V + YL+ K+ + Y+
Sbjct: 424 KDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLT---KKNENYK 480
Query: 1022 ALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQL----RVDALERTLEQKNKEI 1077
+L + + RGK+QQ+Q Q +++Q R E+ ++K KE
Sbjct: 481 SLVRRSYRR-----------RGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEA 529
Query: 1078 EE 1079
E+
Sbjct: 530 EK 531
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
Length = 2524
Score = 65.5 bits (158), Expect = 3e-10
Identities = 111/478 (23%), Positives = 166/478 (34%), Gaps = 99/478 (20%)
Query: 29 QNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPADLESPTLA-ASSYH--GDVV--GQV 83
+N +RK++ P + A V D+ ++ + + E + A + H G+ V G+
Sbjct: 677 RNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGEC 736
Query: 84 STDLIAQRSSDSEE--------AFETPESTTPVKA-------PPAPPPPPPEVIPEPEVS 128
S SSD+E A +T ++ A PP PP PPPE IP P
Sbjct: 737 SGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEP 796
Query: 129 T---------QPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASS 179
T PPP P S + P P P+ + E + PP +E KP A+
Sbjct: 797 TPASEATGAPTPPPAPP---SPSAPPPVVPKEEKEEETAAAPPVEE----GEEQKPPAAE 849
Query: 180 GTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASD 239
VDT + EP S+ + + + K ++ + +L+A
Sbjct: 850 EL---------AVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEG-----ALKAEK 895
Query: 240 FDGASSSGNPEAVALAP-DAYSTGSSSASST-------LKRTKKPRP------------- 278
+G S + AP D+ S+ + SA R PRP
Sbjct: 896 KEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANA 955
Query: 279 ---PSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLE 335
L KQ ++ PP+ EP E P T+ A P P L+
Sbjct: 956 SPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAP----------TKPAPPAPPPPQNLQ 1005
Query: 336 ---ETPLEPAVGPKA-----ACPLDSESAEGVVPP--ASGGGRVQNSPPVGRKTLPLTTA 385
+ P +P P+ A P D E+ + V P A+ ++ PP LP
Sbjct: 1006 PESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVP 1065
Query: 386 P----EAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKP 439
P +A P S P L + L D + NPPP K P
Sbjct: 1066 PREVIKASPHAPDPSAFSYAPPGHPLPLGLH-DTARPVLPRPPTISNPPPLISSAKHP 1122
Score = 40.0 bits (92), Expect = 0.012
Identities = 52/246 (21%), Positives = 83/246 (33%), Gaps = 27/246 (10%)
Query: 249 PEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESL 308
P P + +TG+ + P PP + K++ ++ PPV+E EE
Sbjct: 791 PAPTEPTPASEATGAPTPPPAPPSPSAP-PPVVPKEEKEEETAAAPPVEE-----GEEQK 844
Query: 309 VPSGENLASET-------KTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVP 361
P+ E LA +T K+E + PA ++ A A E G
Sbjct: 845 PPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRAT 904
Query: 362 PASGGGRVQNSPPVGRKTLPLTTAPEAGE-----------VTPSDSGGQEDSPAKGLSVR 410
A G Q+S + E G+ +TP+ SP K L ++
Sbjct: 905 TAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLK 964
Query: 411 LEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKK---TPEKLDNTPASPPRS 467
+ + PP KP P ++ P++ ++P RS
Sbjct: 965 QLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRS 1024
Query: 468 PAEPND 473
PA P D
Sbjct: 1025 PAPPAD 1030
Score = 30.8 bits (68), Expect = 7.3
Identities = 42/182 (23%), Positives = 78/182 (42%), Gaps = 29/182 (15%)
Query: 908 EREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMI--EDEQREKSVSHQTVQ---QLVL 962
E EVSE D E +MR++ I M+ D+QR K ++ + V
Sbjct: 369 EHEVSEIIDGLSEQENLEKQMRQLAV-----IPPMLYDADQQRIKFINMNGLMADPMKVY 423
Query: 963 EKEQALADLNSVEK-SLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQ 1021
+ Q + + EK + + F ++ K ++ F + + V + YL+ K+ + Y+
Sbjct: 424 KDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLT---KKNENYK 480
Query: 1022 ALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQL----RVDALERTLEQKNKEI 1077
+L + + RGK+QQ+Q Q +++Q R E+ ++K KE
Sbjct: 481 SLVRRSYRR-----------RGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEA 529
Query: 1078 EE 1079
E+
Sbjct: 530 EK 531
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 64.7 bits (156), Expect = 5e-10
Identities = 161/791 (20%), Positives = 270/791 (34%), Gaps = 79/791 (9%)
Query: 9 DNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPADLESP 68
D++ ++ T S+ PP + + TP S+P+ + A E+
Sbjct: 478 DSKTQVTTSTEASSSPP--TAEVNSMPTSTPSE------GSTPLTSMSVSTMPVASSEAS 529
Query: 69 TLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPP-PPEVIPEPEV 127
TL+ + D V+T A SS + E P ST + P P ++ E
Sbjct: 530 TLSTTPV--DTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEA 587
Query: 128 STQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHS-----FSAVFDEDKPIASSGTY 182
ST T S + EG+ ++S +++ +ASS
Sbjct: 588 STTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEAS 647
Query: 183 NLDFDNIELVDTFQTLEPRASDAKNQEG-KVNTRRKSTDSVPISKSTLSRSLSLQASDFD 241
L ++ T S + EG + T + S P++ ++ +L +
Sbjct: 648 TLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSE--- 704
Query: 242 GASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQ 301
AS+ P ST +SS+ +T P S + +T P + PV +T
Sbjct: 705 -ASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPT--STPSEGST--PLTSMPVSKTLL 759
Query: 302 EPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVP 361
E S + S L + T ++ SP E T + P P PL + + P
Sbjct: 760 TSSEASTL-STTPLDTSTHITTSTEASCSPTTTEGTSM-PISTPSEGSPLLTSIPVSITP 817
Query: 362 PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSS 421
S ++ PV + P+TT+ E +PA+G S+ YSE ++
Sbjct: 818 VTSPEASTLSTTPVDSNS-PVTTSTEVSS---------SPTPAEGTSMPTS-TYSEGRTP 866
Query: 422 WDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSP---AEPNDIPIAK 478
+ P T + ++ + P TP S P + + P P
Sbjct: 867 LTSM---PVSTTLVATSAISTLSTT-PVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEG 922
Query: 479 GTYTFDIDKWDDP----NFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTP 534
T + P S+T +P P T + + P T S+
Sbjct: 923 STPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGT 982
Query: 535 SSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQ 594
+ + +P S + A++ + L+ TPL T T P + + P+
Sbjct: 983 TPLTSTPVSHTLVANS------EASTLSTTPVDSNTPLTTST-EASSPPPTAEGTSMPTS 1035
Query: 595 DPTPAATPET-PPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNE 653
P+ +TP T PV + +V +++ L+ T D Y Q S ST +
Sbjct: 1036 TPSEGSTPLTRMPVSTTMVASSETSTLSTT-------PADTSTPVTTYSQASSSSTTADG 1088
Query: 654 TKFSSPT--EELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVR 711
T + T E S + + S P DTS PV +S
Sbjct: 1089 TSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTP--------VDTS--IPVTTS-TE 1137
Query: 712 MSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESHL--QVPEKSSQKELEAMGL 769
S SPT G+S + T PV L + E++ P S + +
Sbjct: 1138 ASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEA 1197
Query: 770 GTPSEAIEITA 780
+P E+T+
Sbjct: 1198 SSPPPTAEVTS 1208
Score = 62.0 bits (149), Expect = 3e-09
Identities = 142/750 (18%), Positives = 249/750 (33%), Gaps = 108/750 (14%)
Query: 48 SSSPVADDIIQPAA-------PADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFE 100
+S PV+ ++ +A P D +P ++ T + S+ F
Sbjct: 2164 TSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFT 2223
Query: 101 T-PESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPF 159
+ P ST PV A V V+T +E +P S+
Sbjct: 2224 SMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTS 2283
Query: 160 RPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEG-KVNTRRKS 218
P SH+ +A+S L ++ F T +S EG + T S
Sbjct: 2284 IPVSHTL---------VANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSS 2334
Query: 219 TDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRP 278
+ P+++ +S ++ + F+ ++ S P + YS SS ++ +
Sbjct: 2335 EGNTPLTRMPVSTTM---VASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTST 2391
Query: 279 PSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETP 338
S T P T PV ++ + V + + + T+ S+ T ++ P
Sbjct: 2392 YSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPP 2451
Query: 339 LEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGG 398
E P A+ P+ + P S ++ PV T P+TT+ EA
Sbjct: 2452 SEGTT-PLASMPVST------TPVVSSEAGTLSTTPVDTST-PMTTSTEASS-------- 2495
Query: 399 QEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPK---MKKTPE 455
SP + + + + S+ + PV+ P+ P+ + TP
Sbjct: 2496 ---SPTTAEDIVVPISTASEGSTL------------LTSIPVSTTPVASPEASTLSTTPV 2540
Query: 456 K-----LDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQ 510
+ +T S + AE +P + TY+ P S + P
Sbjct: 2541 DSNSPVVTSTEISSSATSAEGTSMPTS--TYS--------EGSTPLRSMP-VSTKPLASS 2589
Query: 511 QSYNFDPDTCDESVDPFKTSSKTPSSPSK--------------SPASFEIPASAMEANGV 556
++ D S+ P TS++T SSP+ S + I S M
Sbjct: 2590 EASTLSTTPVDTSI-PVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASS 2648
Query: 557 DGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATD 616
+ L+ +T + T T SP + S P+ P +TP T ++S + A
Sbjct: 2649 EASTLSTTPVDTRTLVTTST-GTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANS 2707
Query: 617 EEKLAVTNQKWTCMTVDLEADKQDYP-----------QPSDLSTFVNETKFSS---PTEE 662
E T T V A+ P PSD ST + S+ + E
Sbjct: 2708 EASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSE 2767
Query: 663 LDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQES-------PVKSSPVRMSES 715
++ ++ + +S + + T E+ PV +PV SE+
Sbjct: 2768 ASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEA 2827
Query: 716 PTPCSGSSFEETEALVNTAAKNQHPVPRGL 745
T + T +T A + G+
Sbjct: 2828 GTLSTTPVDTSTPVTTSTKASSSPTTAEGI 2857
Score = 59.3 bits (142), Expect = 2e-08
Identities = 139/715 (19%), Positives = 244/715 (34%), Gaps = 80/715 (11%)
Query: 49 SSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPEST--- 105
S+P+ ++ A E+ T++ ++ + ST+ A S + E P ST
Sbjct: 2750 STPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTE--ASSSPTTAEVTSMPTSTPSE 2807
Query: 106 --TPVKAPPAPPPPPPE----VIPEPEVSTQPPPEEPGCGSETVPVPDG---PRSDSVEG 156
TP+ + P P + V T P S + +G P S + EG
Sbjct: 2808 TSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEG 2867
Query: 157 SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEG-KVNTR 215
S +++ P+ASS L ++ T +S EG +
Sbjct: 2868 STL------LTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPIS 2921
Query: 216 RKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKK 275
S S P++ S L ++ + S+ AS+ P S +SS+ +T + T
Sbjct: 2922 TPSEVSTPLT-SILVSTVPVAGSE---ASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSM 2977
Query: 276 P-RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALL 334
P P ++ T T PV ++ + + + + T+ S+ T +
Sbjct: 2978 PISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIP 3037
Query: 335 EETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPS 394
TP E + P + P+ + +P AS TL T V S
Sbjct: 3038 ISTPSEGST-PLTSIPVSTTPV--AIPEAS--------------TLSTTPVDSNSPVVTS 3080
Query: 395 DSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTP 454
+PA+G S+ + YSE + + P ++ P+ T
Sbjct: 3081 TEVSSSPTPAEGTSMPIS-TYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTS 3139
Query: 455 EKLDNTPAS------PPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKL 508
+ ++P + P +P+E + T + +D S + + S +
Sbjct: 3140 TEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTL----SATPVDTSTPV 3195
Query: 509 PQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKK 568
+ T + + P T S+ + + P S P ++ EA+ L+
Sbjct: 3196 TTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVS-NTPVASSEASI-----LSTTPVDS 3249
Query: 569 KTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWT 628
TPL T T SP + + P+ P+ +TP T +S A+ E T T
Sbjct: 3250 NTPLTTST-EASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADT 3308
Query: 629 CMTVDLEADKQDYPQPSDLSTFVNET--KFSSPTEELDYRNSYEIEYMEKIGSSLPQDDD 686
V + P +D ++ T + S+P + + + + S+ P D
Sbjct: 3309 STPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTS 3368
Query: 687 APKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPV 741
P TS E+ S SPT G+S + T PV
Sbjct: 3369 TP--------VTTSTEA---------SLSPTTAEGTSIPTSSPSEGTTPLASMPV 3406
Score = 58.5 bits (140), Expect = 3e-08
Identities = 141/700 (20%), Positives = 225/700 (32%), Gaps = 126/700 (18%)
Query: 62 PADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFET-PESTTPVKAPPA------P 114
P D ++ AS T + S+ + P STTPV + A P
Sbjct: 417 PVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTP 476
Query: 115 PPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDK 174
+V E S+ PP T V P S EGS P S S
Sbjct: 477 VDSKTQVTTSTEASSSPP---------TAEVNSMPTSTPSEGST---PLTSMSV---STM 521
Query: 175 PIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEG-KVNTRRKSTDSVPISKSTLSRSL 233
P+ASS L ++ T +S + EG + T S S P++ +S L
Sbjct: 522 PVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRL 581
Query: 234 SLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTET 293
+ + AS++ A + S+ +SS+S+T + T P + ++ TT
Sbjct: 582 VVSSE----ASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTS-TYSERGTTITSMSV 636
Query: 294 PPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDS 353
E S P N T TE+ S E T + + + + PL S
Sbjct: 637 STTLVASSEASTLSTTPVDSNTPVTTSTEATS----SSTTAEGTSMPTSTYTEGSTPLTS 692
Query: 354 ESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEF 413
+ AS ++ PV T P+TT+ EA + A G S+
Sbjct: 693 MPVNTTLV-ASSEASTLSTTPVDTST-PVTTSTEASS---------SPTTADGASM---- 737
Query: 414 DYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPND 473
P T G P+ MP+ + + + +T
Sbjct: 738 ---------------PTSTPSEGSTPLTSMPVSKTLLTSSEASTLST------------- 769
Query: 474 IPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKT 533
P +++ + S + + P T + + P T S+
Sbjct: 770 --------------------TPLDTSTHITTSTEA-----SCSPTTTEGTSMPISTPSEG 804
Query: 534 PSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPS 593
SP IP S + L+ +P+ T T V SP + + P+
Sbjct: 805 ------SPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTST-EVSSSPTPAEGTSMPT 857
Query: 594 QDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNE 653
+ TP T +S + AT T T V + + P S+ ++
Sbjct: 858 STYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTS 917
Query: 654 T--KFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVR 711
T + S+P + + + + S+ P D P TS E+
Sbjct: 918 TPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTP--------VTTSTEA-------- 961
Query: 712 MSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQES 751
+ SPT G+S + T PV L N E+
Sbjct: 962 -TSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEA 1000
Score = 58.5 bits (140), Expect = 3e-08
Identities = 154/766 (20%), Positives = 251/766 (32%), Gaps = 94/766 (12%)
Query: 7 TSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPG--------SPDHRDASSSPVADDIIQ 58
TS TLS S P S + G S +S PV+ ++
Sbjct: 819 TSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVA 878
Query: 59 PAA-------PADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFET-PESTTPVKA 110
+A P D +P ++ T + + + P+STTPV +
Sbjct: 879 TSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVS 938
Query: 111 PPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVF 170
A V V+T +E +P S+ P SH+
Sbjct: 939 SEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTL---- 994
Query: 171 DEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEG-KVNTRRKSTDSVPISKSTL 229
+A+S L ++ T +S EG + T S S P+++ +
Sbjct: 995 -----VANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPV 1049
Query: 230 SRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPP-SLKKKQTTK 288
S ++ + + ++ S P + YS SSS S+T T P S T
Sbjct: 1050 STTM---VASSETSTLSTTPADTSTPVTTYSQASSS-STTADGTSMPTSTYSEGSTPLTS 1105
Query: 289 KPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAA 348
P T V E S P ++ T TE++ SP E T + + +
Sbjct: 1106 VPVSTRLV--VSSEASTLSTTPVDTSIPVTTSTEASS----SPTTAEGTSIPTSPPSEGT 1159
Query: 349 CPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTA-----PEAGEVT--PSDSGGQED 401
PL S + +S + ++ PV KT T+ P EVT P+ + G+
Sbjct: 1160 TPLASMPVSTTLVVSSEANTL-STTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERS 1218
Query: 402 SPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTP 461
+P + VR S + S+ T + T E
Sbjct: 1219 TPLTSMPVRHTPVASSEASTLS--------TSPVDTSTPVTTSAETSSSPTTAEGTSLPT 1270
Query: 462 ASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCD 521
++ IP++ T P + +T + P + + P +
Sbjct: 1271 STTSEGSTLLTSIPVSTTLVT-------SPEASTLLTTPVDTKGPVVTSNEVSSSPTPAE 1323
Query: 522 ESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKK 581
+ P T S+ + + P + + AS+ + L+ TP+ T T
Sbjct: 1324 GTSMPTSTYSEGRTPLTSIPVNTTLVASSAISI------LSTTPVDNSTPVTTST-EACS 1376
Query: 582 SPKRSPLSDPPSQDPTPAATPETP-PVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQD 640
SP S + P+ +P+ TP T PV + V +++ L+ T
Sbjct: 1377 SPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSAT----------------- 1419
Query: 641 YPQPSDLST--FVNETKFSSPT--EELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYL- 695
P D ST + SSPT E + S E + S + +A L
Sbjct: 1420 ---PVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLS 1476
Query: 696 MFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPV 741
SPV +S +S SPTP G+S + + A PV
Sbjct: 1477 TTPVDSNSPVVTS-TAVSSSPTPAEGTSIAISTPSEGSTALTSIPV 1521
Score = 57.4 bits (137), Expect = 7e-08
Identities = 157/783 (20%), Positives = 258/783 (32%), Gaps = 137/783 (17%)
Query: 46 DASSSPVADDI--IQPAAPADLESPTLAASSYHGDVV----GQVSTDLIAQRS--SDSEE 97
+ASSSP ++ + + P++ +P + H V G +ST + + + S +
Sbjct: 2787 EASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTK 2846
Query: 98 AFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDG-PRSDSVEG 156
A +P + + P + ++ VST P T PV P + S EG
Sbjct: 2847 ASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEG 2906
Query: 157 S-----------PFRPPSH---SFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRA 202
S P PS +++ P+A S L ++ T +
Sbjct: 2907 SSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEAS 2966
Query: 203 SDAKNQEGKVNTRRKSTDSVPISKS------TLSRSLSLQASDFDGASSSGNPEAVALAP 256
S EG S+PIS S S+S AS+ A P
Sbjct: 2967 SSPTTAEGT---------SMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTP 3017
Query: 257 DAYSTGSSSASSTLKRTKKP-RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENL 315
ST +SS+ +T + T P PS T P T PV + + V S +
Sbjct: 3018 VTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPV 3077
Query: 316 ASETKTESAKT-------------EGPSPAL---LEETPL-EPAVGPKAACPLDSE---- 354
+ T+ S+ T EG +P + TP+ A+ + P+D+
Sbjct: 3078 VTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVT 3137
Query: 355 -SAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEF 413
S E P + G + + PLT P + + S + S +
Sbjct: 3138 TSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTT 3197
Query: 414 DYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRR-PKMKKTPEKLDNTPA---SPPRSPA 469
S+ P T G P+ +P+ P L TP +P +
Sbjct: 3198 STEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTST 3257
Query: 470 EPNDIP-IAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCD----ESV 524
E + P A+GT P P ++ + P + + T ++
Sbjct: 3258 EASSSPPTAEGTSM--------PTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTS 3309
Query: 525 DPFKTSSKTPSSP-----SKSPASFEIPASAMEAN---------GVDGDGLNKPAKKKKT 570
P T S+ SSP + P S S N + L+ T
Sbjct: 3310 TPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTST 3369
Query: 571 PLKTDTFRVKKSPKRSPLSDPPSQDPTPAATP-ETPPVISAVVHATDEEKLAVTNQKWTC 629
P+ T T SP + + P+ P+ TP + PV + V +++ L+ T
Sbjct: 3370 PVTTST-EASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTT------ 3422
Query: 630 MTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPK 689
P D +T V + +S + + G+SLP +
Sbjct: 3423 --------------PVDSNTLVTTSTEASSSPTIAE------------GTSLPTSTTSEG 3456
Query: 690 KQALYLM-----------FDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQ 738
L +M T +PV +S + SPT S ++ E T +TA +
Sbjct: 3457 STPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGS 3516
Query: 739 HPV 741
P+
Sbjct: 3517 TPL 3519
Score = 54.7 bits (130), Expect = 5e-07
Identities = 136/700 (19%), Positives = 240/700 (34%), Gaps = 89/700 (12%)
Query: 49 SSPVADDIIQPAA--PADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFET-PEST 105
++PVA I + P D +P ++ T + S+ + P ST
Sbjct: 1699 TTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVST 1758
Query: 106 TPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHS 165
TPV + A + V+T +E +P S+ + P SH+
Sbjct: 1759 TPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHT 1818
Query: 166 FSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKST-DSVPI 224
A + ++ T +D ++ + T + P ++ + + + S+P+
Sbjct: 1819 LVA----NSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPV 1874
Query: 225 SKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKK 284
S +T++ S + S +S+ ++ + SS ++ R +P S+
Sbjct: 1875 STTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVS 1934
Query: 285 QTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLE-ETPLEP-- 341
TT +E + T + S AS + T + T P+PA E TPL
Sbjct: 1935 TTTVASSEINTLSTTLADTRTPVTTYSQ---ASSSPTTADGTSMPTPAYSEGSTPLTSMP 1991
Query: 342 -----AVGPKAAC----PLDSE-----SAEGVVPPASGGG-RVQNSPPVGRKTLPLTTAP 386
V +A+ P+D+ S EG P + GG +Q S P +T PL P
Sbjct: 1992 LSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTP-SERTTPLAGMP 2050
Query: 387 EAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLR 446
+ + S G L + K+ N E G P
Sbjct: 2051 VSTTLVVSSEGN-----------TLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSE 2099
Query: 447 -RPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQES 505
P + P L TP + P A T +D + +P +++++ S
Sbjct: 2100 GSPLLTSIP--LSTTPVASPE----------ASTLSTTPVD-----SNSPVITSTEVSSS 2142
Query: 506 PKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPA 565
P +P + + T + P + P S + AS+ + L+
Sbjct: 2143 P-IPTEGTSMQTSTYSDRRTPL----------TSMPVSTTVVASSAIST------LSTTP 2185
Query: 566 KKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQ 625
TP+ T++ + SP S + P+ P+ +TP T +S + T E
Sbjct: 2186 VDTSTPV-TNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATP 2244
Query: 626 KWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIG--SSLPQ 683
T V + P ++ ++ T T S+ + ++ S+ P
Sbjct: 2245 VDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPV 2304
Query: 684 DDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSS 723
D + P F TS E+ S P + P S SS
Sbjct: 2305 DSNTP--------FTTSTEA--SSPPPTAEGTSMPTSTSS 2334
Score = 54.3 bits (129), Expect = 6e-07
Identities = 123/588 (20%), Positives = 201/588 (34%), Gaps = 89/588 (15%)
Query: 53 ADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPP 112
++D A P D +P ++ + ++ + S P S TPV +
Sbjct: 3179 SEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSE 3238
Query: 113 APPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDG---PRSDSVEGSPFRPPSHSFSAV 169
A ++ V + P S + P +G P S EGS +++
Sbjct: 3239 A------SILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGST------PLTSM 3286
Query: 170 FDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEG-KVNTRRKSTDSVPISKST 228
+ASS T L + T +S +G + T S S P++ +
Sbjct: 3287 PVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMS 3346
Query: 229 LSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRP-PSLKKKQTT 287
S + + + AS+ P ST +S + +T + T P PS
Sbjct: 3347 FSTTPVVSSE----ASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLA 3402
Query: 288 KKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKA 347
P T PV E + S P N T TE++ SP + E T L + +
Sbjct: 3403 SMPVSTTPV--VSSEVNTLSTTPVDSNTLVTTSTEASS----SPTIAEGTSLPTSTTSEG 3456
Query: 348 ACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTA------PEAGEVT--PSDSGGQ 399
+ PL S P AS ++ PV T P+TT+ P EVT P+ + G+
Sbjct: 3457 STPL-SIMPLSTTPVASSEASTLSTTPVDTST-PVTTSSPTNSSPTTAEVTSMPTSTAGE 3514
Query: 400 EDSPAKGLSVRLEFDYSEDKSSWD-------------NQQENPPPTKKIGKKPVAKMPLR 446
+P + V S + S+ +Q + P T + V M +
Sbjct: 3515 GSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQ-----VTTMRMS 3569
Query: 447 RPK--------MKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSS 498
P M + + ++ AS P +P+ P+ T + + P S+
Sbjct: 3570 TPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMST 3629
Query: 499 TSKMQESPKLPQQSYNFDPDTCDES-------VD---PFKTSSKTPSSP----------- 537
S++ S L + T E+ VD P TS++ SSP
Sbjct: 3630 PSEV--STPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIW 3687
Query: 538 ---SKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKS 582
S +P S +G L+ P+ TP+ T T + S
Sbjct: 3688 TPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSS 3735
Score = 53.5 bits (127), Expect = 1e-06
Identities = 160/776 (20%), Positives = 257/776 (33%), Gaps = 108/776 (13%)
Query: 9 DNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPADLESP 68
D++ ++ T S+ PP + + TPG S+P+ ++ A E+
Sbjct: 1186 DSKTQVATSTEASSPPP--TAEVTSMPTSTPGE------RSTPLTSMPVRHTPVASSEAS 1237
Query: 69 TLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPP-PPPPEVIPEPEV 127
TL+ S D V+T S + E P STT + P ++ PE
Sbjct: 1238 TLSTSPV--DTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEA 1295
Query: 128 ST--QPPPEEPG---CGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTY 182
ST P + G +E P S+ S + +++ +ASS
Sbjct: 1296 STLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAIS 1355
Query: 183 NLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTD------SVPISKSTL--SRSLS 234
L ++ T S EG ++ S+P+S + + S + +
Sbjct: 1356 ILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEAST 1415
Query: 235 LQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETP 294
L A+ D S+ G A A + + G S +ST PS K P
Sbjct: 1416 LSATPVD-TSTPGTTSAEATSSPTTAEGISIPTST---------PSEGKTPLKSIPVSNT 1465
Query: 295 PVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSE 354
PV ++ + V S + + T S+ T PA G A SE
Sbjct: 1466 PVANSEASTLSTTPVDSNSPVVTSTAVSSSPT--------------PAEGTSIAISTPSE 1511
Query: 355 SAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFD 414
+ + V +S T P T+ VT + A G S++
Sbjct: 1512 GSTALTSIPVSTTTVASSEINSLSTTPAVTSTP---VTTYSQASSSPTTADGTSMQTS-T 1567
Query: 415 YSEDKSSWDN----------QQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASP 464
YSE + + + N T I K T E T ++P
Sbjct: 1568 YSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASS-STTAEGSSMTISTP 1626
Query: 465 PRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESV 524
IP++ P + S+T SP + + P + +
Sbjct: 1627 SEGSPLLTSIPVSTTPVA-------SPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTS 1679
Query: 525 DPFKT--SSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKS 582
P T +TP + S + + + +SA+ L+ TP+ T T + S
Sbjct: 1680 MPTSTYTEGRTPLT-SITVRTTPVASSAIST-------LSTTPVDNSTPVTTST-EARSS 1730
Query: 583 PKRSPLSDPPSQDPTPAATPETP-PVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDY 641
P S + P+ P+ TP T PV + V +++ L+ T
Sbjct: 1731 PTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSAT------------------ 1772
Query: 642 PQPSDLSTFVNETK--FSSPT--EELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMF 697
P D ST V + SSPT E S E M + S+ +A L
Sbjct: 1773 --PIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLST 1830
Query: 698 D-TSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESH 752
SPV +S +S SPTP G+S + + A PV + E++
Sbjct: 1831 TPVDSNSPVVTSTA-VSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETN 1885
Score = 45.8 bits (107), Expect = 2e-04
Identities = 161/789 (20%), Positives = 273/789 (34%), Gaps = 126/789 (15%)
Query: 6 STSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPADL 65
STSD+ + T ++ P + D P S ++ SS +A + A
Sbjct: 121 STSDSTTLFPSSTEDTSSPT------TPEGTDVPMSTPSEESISSTMA--FVSTAPLPSF 172
Query: 66 ESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPEST-----TPVKAPPAPPPPPPE 120
E+ T + +Y D+ ++T A S + E+ P+ST TP+ + PA
Sbjct: 173 EAYT--SLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVAS 230
Query: 121 -----VIPEP-EVSTQPPPEEPGCGSETVPVPDGPR-SDSVEGSPFRPPSHSFSAVFDED 173
++ P E+ST P S + +GP S+S P + +V
Sbjct: 231 SEAITLLTTPVEIST--PVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVV 288
Query: 174 KPIASSGTYNLDFDNIELV-DTFQTLEPRASDAKN------QEGKVNTRRKSTDSVPISK 226
AS+ + NI ++ T + P ++ + EG ++P++
Sbjct: 289 SSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVAT 348
Query: 227 STLSRSLSLQASDFDG-ASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQ 285
S +S +LS+ D ++S P ++ +A +S +STL P
Sbjct: 349 SEMS-TLSITPVDTSTLVTTSTEPSSLPTTAEA----TSMLTSTLSEGSTP--------- 394
Query: 286 TTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGP 345
T P T + E S +P + S+T +A SP E+T + +
Sbjct: 395 LTNMPVST--ILVASSEASTTSTIP----VDSKTFVTTASEASSSPTTAEDTSIATSTPS 448
Query: 346 KAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLT-----TAPEAGEVT--PSDSGG 398
+ + PL S P AS ++ PV KT T ++P EV P+ +
Sbjct: 449 EGSTPLTSMPV-STTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPS 507
Query: 399 QEDSPAKGLSV--------------------RLEFDYSEDKSSWDNQQEN---PPPTKKI 435
+ +P +SV S + SS E P T
Sbjct: 508 EGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSE 567
Query: 436 GKKPVAKMPL-RRPKMKKTPEKLDNTP------------ASPPRSPAEPNDIPIAKGTYT 482
G P+ MP+ R + TP AS + AE +P T T
Sbjct: 568 GSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMP----TST 623
Query: 483 FDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFD-PDTCDESVDPFKTSSKTPSSPSKSP 541
+ + + ++ E+ L + + P T T+++ S P+ +
Sbjct: 624 YSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTY 683
Query: 542 ASFEIPASAMEAN-----GVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDP 596
P ++M N + L+ TP+ T T SP + + P+ P
Sbjct: 684 TEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTST-EASSSPTTADGASMPTSTP 742
Query: 597 TPAATPETP-PVISAVVHATDEEKLAVTN-QKWTCMTVDLEADKQDYPQPSDLSTFVNET 654
+ +TP T PV ++ +++ L+ T T +T EA S +T
Sbjct: 743 SEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEA------SCSPTTTEGTSM 796
Query: 655 KFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSE 714
S+P+E S + P SPV +S +S
Sbjct: 797 PISTPSEGSPLLTSIPVSITPVTSPEASTLSTTP----------VDSNSPVTTS-TEVSS 845
Query: 715 SPTPCSGSS 723
SPTP G+S
Sbjct: 846 SPTPAEGTS 854
>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
sapiens]
Length = 1393
Score = 63.9 bits (154), Expect = 8e-10
Identities = 168/842 (19%), Positives = 275/842 (32%), Gaps = 144/842 (17%)
Query: 7 TSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDH--RDASSSPVADDIIQPAAPAD 64
T+ N++T TP A+P N Q + T S +P+A++ P+
Sbjct: 485 TTANEKT----TPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEP 540
Query: 65 LES----------PTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAP 114
E+ P+ A + +GD + + +E TP + + A
Sbjct: 541 TENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAE 600
Query: 115 PPPPPEVIPEPEVSTQPPPEEP------GCGSETVPVPDGP------------------- 149
P E P +T P P EP T P P GP
Sbjct: 601 PTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEP 660
Query: 150 -------RSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRA 202
++ SP P + F +K +SS + L + TL P
Sbjct: 661 TENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSP-- 718
Query: 203 SDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYS-- 260
A+ E + T + T P + + + + A + N + LA + +
Sbjct: 719 --AEPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPS 776
Query: 261 -------------TGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEES 307
+ SS+ + T+ L + TT P E P + ++ +E++
Sbjct: 777 LAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAE--PTENRERTANEKT 834
Query: 308 LVPSGENLASETKTESAKTEGPSPA---------LLEETPLEPA--VGPKAACPLDSESA 356
E + T + KT P PA E T L PA + PL +E
Sbjct: 835 TQFPAEPTENRESTANEKTT-PFPAEPTENREWTANENTTLSPAEPTEHEEMTPLANEKT 893
Query: 357 EGVVPPASGGGRVQNSPPVGRKTLPLTTAP-EAGEVTPSDSGGQEDSPAKGLSVRLEFDY 415
+ PA + +P KT P + P E GE TP A ++ +
Sbjct: 894 --TLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPL---------ANEITTPSRAEP 942
Query: 416 SEDKSSWDNQQENPPPTK-------KIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSP 468
+E N++ P P K + + ++TP +NT SP S
Sbjct: 943 TEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTPLANENTTTSPTES- 1001
Query: 469 AEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDP----DTCDESV 524
E + + T + + P S+ K SP P + P +T V
Sbjct: 1002 TEHGERTANEKTTPSPAEPTEHGERTP-SANEKTIPSPAKPTEHEEMTPSANENTTPSPV 1060
Query: 525 DPFKTSSKTPSSPSKSPASFEIP----ASAMEANGVDGDGLNKPAKK-KKTPLKTDTFRV 579
P + KT + K S E P A AN L KP + ++T D
Sbjct: 1061 KPTEHGEKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKI-- 1118
Query: 580 KKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQ 639
S +D +A TP + HA ++ + ++K T +T
Sbjct: 1119 ----TSSAAESTEHRDRATSANVITPAPAEPIKHA---KRTTLAHEKMTQVT----EKST 1167
Query: 640 DYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDT 699
++P+ K +S TE+ Y EK + ++ P+K L T
Sbjct: 1168 EHPE-----------KTTSTTEKTTRTPEKPTLYSEKTICTKGKNTPVPEKPTENLGNTT 1216
Query: 700 SQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQVPEKS 759
+K +PV+ +E+P E+T A+ T + SHL E +
Sbjct: 1217 LTTETIK-APVKSTENP--------EKTAAVTKTIKPSVKVTGDKSLTTTSSHLNKTEVT 1267
Query: 760 SQ 761
Q
Sbjct: 1268 HQ 1269
Score = 56.6 bits (135), Expect = 1e-07
Identities = 157/804 (19%), Positives = 265/804 (32%), Gaps = 84/804 (10%)
Query: 6 STSDNQRTLSA-QTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADD--IIQPAAP 62
+T + Q T+SA + +S P + +TP SP + A++ + PA P
Sbjct: 265 TTKNIQETISANELTQSLAEPTEHGGRTANENNTP-SPAEPTENRERTANENTTLSPAEP 323
Query: 63 ADLESPTLAASSYHGDVVGQVSTDLIAQRSSD--SEEAFETPESTTPVKAPPAPPPPPPE 120
+ T ++ + ++ A ++ E E E T P+P P
Sbjct: 324 IENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEH 383
Query: 121 VIPEPEVSTQPPPEEPGCGSETVP-VPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASS 179
+T P P EP E P D S S E S E P+A+
Sbjct: 384 GERTANENTTPSPAEPTEHGERTPFANDKTTSSSAE-----------STEHGERTPLANE 432
Query: 180 GTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASD 239
T + E + S A E + T + T P+ + + + + +
Sbjct: 433 NTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTT 492
Query: 240 FDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKET 299
A + N + A + T SSSA T + P L + TT P E P +
Sbjct: 493 PSPAEPTENGQRTPFANE--KTTSSSAEPTEHGERTP----LANENTTPSPAE--PTENR 544
Query: 300 QQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGV 359
++ +E++ E + +T A E +P+L E T P A S SAE
Sbjct: 545 ERTANEKTTPSPAEPTENGDRTPLA-NEKTTPSLAEPTENGQRT-PFANEKTTSSSAEPT 602
Query: 360 VPPASGGGRVQNSPPVGRKTLPLTTAPEAG-------EVTPSDSGGQEDS---------- 402
+ +P T P P TPS +G E+
Sbjct: 603 -------EHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTL 655
Query: 403 -PAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTP 461
PA+ R + SS EN T +K + ++TP +NT
Sbjct: 656 FPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTT 715
Query: 462 ASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDP---- 517
S P P E + + T F + ++ +T+ SP P ++ + P
Sbjct: 716 LS-PAEPTENRERTANEKTTPFPAEPTENRERTANENTT---PSPAQPTENGDRTPLANE 771
Query: 518 DTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDG-LNKPAKKKKTPLKTDT 576
T +P + +TP + K+ +S P E + + + PA+ + +T
Sbjct: 772 KTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTAN 831
Query: 577 FRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEA 636
+ + P P+++ A +T P + N++WT +
Sbjct: 832 EKTTQFPAE------PTENRESTANEKTTPFPAE----------PTENREWTA-NENTTL 874
Query: 637 DKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLM 696
+ + +++ NE SP E + + SS + + +
Sbjct: 875 SPAEPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPLANEI 934
Query: 697 FDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVN--TAAKNQHPVPRG---LAPNQES 751
S+ P + +E TP E E VN T + P G N+ +
Sbjct: 935 TTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTPLANENT 994
Query: 752 HLQVPEKSSQKELEAMGLGTPSEA 775
E + E A TPS A
Sbjct: 995 TTSPTESTEHGERTANEKTTPSPA 1018
Score = 39.3 bits (90), Expect = 0.021
Identities = 85/427 (19%), Positives = 143/427 (33%), Gaps = 60/427 (14%)
Query: 4 ENSTSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPA 63
E + N++T TP SA+P + + + T S +A++ P+
Sbjct: 905 ERTPFTNEKT----TPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIANEKATPSPAK 960
Query: 64 DLE----------SPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETP-ESTTPVKAPP 112
E +P+ A + +G+ + + + +E T E TTP A P
Sbjct: 961 PTEHGETTVNEDTTPSSAEPTENGERTPLANENTTTSPTESTEHGERTANEKTTPSPAEP 1020
Query: 113 AP-----PPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFS 167
P + IP P T+ P T P SP +P H
Sbjct: 1021 TEHGERTPSANEKTIPSPAKPTEHEEMTPSANENTTP------------SPVKPTEHGEK 1068
Query: 168 AVFDEDK-PIASSGTYNLDFDNIELVDTFQTLEPR-ASDAKNQEGKVNTRRKSTDSVPIS 225
+K ++ G + + + P A ++ E + K T S S
Sbjct: 1069 TTLANEKITLSPEGPTE---HGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAES 1125
Query: 226 KSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYST--------GSSSASSTLKRTKKPR 277
R+ S A + + LA + + + S+T K T+ P
Sbjct: 1126 TEHRDRATSANVITPAPAEPIKHAKRTTLAHEKMTQVTEKSTEHPEKTTSTTEKTTRTPE 1185
Query: 278 PPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASET-KTESAKTEGPSPALLEE 336
P+L ++T + PV E +P E L +ET K TE P
Sbjct: 1186 KPTLYSEKTICTKGKNTPVPE---KPTENL---GNTTLTTETIKAPVKSTENPEKTAAVT 1239
Query: 337 TPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDS 396
++P+V L + S+ V + P G TL +T+ + +T S++
Sbjct: 1240 KTIKPSVKVTGDKSLTTTSSH------LNKTEVTHQVPTGSFTL-ITSRTKLSSIT-SEA 1291
Query: 397 GGQEDSP 403
G E P
Sbjct: 1292 TGNESHP 1298
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 63.5 bits (153), Expect = 1e-09
Identities = 121/591 (20%), Positives = 221/591 (37%), Gaps = 67/591 (11%)
Query: 194 TFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVA 253
T + E +AK +EGK + ++ + T S A + +PE A
Sbjct: 467 TEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPP----------AEEAASPEKEA 516
Query: 254 LAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGE 313
+P S + + + ++ + P +K + K P + +E + P+ +S P E
Sbjct: 517 KSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAK----EEAKSPPEAKS--PEKE 570
Query: 314 NLASETKTESAKTEGPSPALLE-ETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNS 372
S + +S + + SPA E ++P E KA P+ E+ PA V+
Sbjct: 571 EAKSPAEVKSPE-KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS----PAEAKSPVKEE 625
Query: 373 PPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPT 432
K+ +PE + S + + SP K S E S +K+ + E P
Sbjct: 626 A----KSPAEVKSPEKAK---SPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPE 678
Query: 433 KKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPA-EPNDIPIAKGTYTFDIDKWDDP 491
K K PV K + P+ K+P K + +SP E P + + K +
Sbjct: 679 K--AKSPV-KAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEK 735
Query: 492 NFNPFSSTSKMQESPKLPQQSYNFD----------PDTCDESVDPFKTSSKTP-----SS 536
+P +K E K P+++ D + D F +K+P S
Sbjct: 736 AKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKS 795
Query: 537 PSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRS----PLSDPP 592
P K+ + + A A E + + P K+++ P + +VK+ PK++ + P
Sbjct: 796 PEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEV---KVKEPPKKAEEEKAPATPK 852
Query: 593 SQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLE--ADKQDYPQPSDLSTF 650
+++ + E P + ++++ AV K + + E DK+ P P +
Sbjct: 853 TEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPA 912
Query: 651 VNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPV 710
E K + +E E + + S P A KK+A DT +E K
Sbjct: 913 KVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKP----AEKKEAAPEKKDTKEEKAKK---- 964
Query: 711 RMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQ 761
E + E+ + L +K + + + + PEK+++
Sbjct: 965 --PEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATE 1013
Score = 63.5 bits (153), Expect = 1e-09
Identities = 97/456 (21%), Positives = 170/456 (37%), Gaps = 33/456 (7%)
Query: 22 AQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPADLESPTLAASSYHGDVVG 81
A+ P +++ ++++ +P + + SP ++ +PA+ +SP A S V
Sbjct: 558 AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA---KSPAEAKSPEKAKSP-----VK 609
Query: 82 QVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSE 141
+ + +S EEA +S VK+P P E PE + P EE +
Sbjct: 610 EEAKSPAEAKSPVKEEA----KSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK 665
Query: 142 TV-PVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEP 200
PV +S SP + + S K A S E + P
Sbjct: 666 AKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725
Query: 201 RASDAKNQEGKVNTRRKSTDSVPISKST-LSRSLSLQASDFDGASSSGNPEAVALAPDAY 259
+AK E + ++ S +KS +++L +++ + A + EA + A
Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPE---AKTPAKEEARSPADKFP 782
Query: 260 STGSSSASSTLKRTKKPRPP-----SLKKKQTTKKPTETPPVKETQQEPDEESLVPSGEN 314
S +K +K + P +K+ KK PVKE +++P E + +
Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKE-EEKPQEVKVKEPPKK 841
Query: 315 LASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPP 374
E + KTE + EE P + A PK ++ + V P +
Sbjct: 842 AEEEKAPATPKTEEKKDSKKEEAPKKEAPKPK----VEEKKEPAVEKPKESKVEAKKEEA 897
Query: 375 VGRKTLPLTT--APEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPT 432
+K +P AP EV ++ AK + D + S +++ P
Sbjct: 898 EDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAK----KEPDDAKAKEPSKPAEKKEAAPE 953
Query: 433 KKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSP 468
KK K+ AK P +PK + ++ D T + P P
Sbjct: 954 KKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKP 989
Score = 63.2 bits (152), Expect = 1e-09
Identities = 124/619 (20%), Positives = 215/619 (34%), Gaps = 111/619 (17%)
Query: 26 GNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAA--PADLESPTLAASSYHGDVVGQV 83
G + + +++T P AS A ++ A PA+ +SP + +V
Sbjct: 489 GEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPE 548
Query: 84 STDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV 143
+S EEA PE+ +P K P + PE + P EE +E
Sbjct: 549 KA-----KSPAKEEAKSPPEAKSPEKEEAKSPAE----VKSPEKAKSPAKEEAKSPAE-A 598
Query: 144 PVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRAS 203
P+ +S E + + P+ + S V +E K A E+ + P
Sbjct: 599 KSPEKAKSPVKEEA--KSPAEAKSPVKEEAKSPA------------EVKSPEKAKSPTKE 644
Query: 204 DAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGS 263
+AK+ E + ++ S +KS + +A A +P+ +
Sbjct: 645 EAKSPEKAKSPEKEEAKSPEKAKSPV--------------------KAEAKSPEKAKSPV 684
Query: 264 SSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTES 323
+ + + ++ K P K + K PVKE + P++ E E
Sbjct: 685 KAEAKSPEKAKSPVKEEAKSPEKAKS-----PVKEEAKSPEKAKSPVKEEAKTPEKAKSP 739
Query: 324 AKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLT 383
K E SP E A P+ A LD +S E P + P K+ P+
Sbjct: 740 VKEEAKSP--------EKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKS-PVK 790
Query: 384 TAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKM 443
++ E S +P K E E+ S ++E P K+ + P
Sbjct: 791 EEVKSPEKAKSPLKEDAKAPEK------EIPKKEEVKSPVKEEEKPQEV-KVKEPPKKAE 843
Query: 444 PLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQ 503
+ P KT EK D+ P+ A + K +
Sbjct: 844 EEKAPATPKTEEKKDSKKEEAPKKEAPKPKV------------------------EEKKE 879
Query: 504 ESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASA----------MEA 553
+ + P++S + + + K P+ ++PA E+ A E
Sbjct: 880 PAVEKPKES------KVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEP 933
Query: 554 NGVDGDGLNKPAKKKK-TPLKTDTFRVK-KSPKRSPLSDPPSQ--DPTPAATPETPPVIS 609
+ +KPA+KK+ P K DT K K P+ P ++ ++ D T + P P
Sbjct: 934 DDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEK 993
Query: 610 AVVHATDEEKLAVTNQKWT 628
A ++ ++K + +K T
Sbjct: 994 AEKSSSTDQKDSKPPEKAT 1012
Score = 42.7 bits (99), Expect = 0.002
Identities = 102/498 (20%), Positives = 194/498 (38%), Gaps = 59/498 (11%)
Query: 596 PTPAATPETPPVISAV---VHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVN 652
P P + PE P I +V + EEK+ V +K TV +E ++ +++
Sbjct: 417 PIPFSLPEGLPKIPSVSTHIKVKSEEKIKVV-EKSEKETVIVEEQTEETQVTEEVTEEEE 475
Query: 653 ETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDA-PKKQALYLMFDTSQESPVKSSPVR 711
+ +E + E E E+ S P ++ A P+K+A +SPVK
Sbjct: 476 KEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEA---------KSPVKE---- 522
Query: 712 MSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGT 771
E+ +P S E+ EA K+ + +P +E PE S ++ EA
Sbjct: 523 --EAKSPAEAKSPEKEEAKSPAEVKSPE---KAKSPAKEEAKSPPEAKSPEKEEA----- 572
Query: 772 PSEAIEITAPEGSFASADALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFA 831
E+ +PE + + A P P E P A+ +E +
Sbjct: 573 -KSPAEVKSPEKAKSPAK---EEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKS 628
Query: 832 IMRIEALKLAR-----QIALASRSHQDAKREAAHPTDVSISKTALYSRIGTAEVEK-PAG 885
+++ + A+ + ++ K EA P +K+ + + + E K P
Sbjct: 629 PAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK---AKSPVKAEAKSPEKAKSPVK 685
Query: 886 LLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIED 945
+ P+ A + E + E+ S K++ + + +++ EK + + E+
Sbjct: 686 AEAKSPE--KAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEE 743
Query: 946 EQR-EKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKR 1004
+ EK+ S + + L ++ +A +S AD F EK K ++ K+ E K
Sbjct: 744 AKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFP--EKAKSPVKEEVKSPEKAKS 801
Query: 1005 CAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVD 1064
+E +KE + + +K +E+ ++ + KA++E+A
Sbjct: 802 PLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA-------------P 848
Query: 1065 ALERTLEQKNKEIEELTK 1082
A +T E+K+ + EE K
Sbjct: 849 ATPKTEEKKDSKKEEAPK 866
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 63.2 bits (152), Expect = 1e-09
Identities = 76/353 (21%), Positives = 145/353 (41%), Gaps = 47/353 (13%)
Query: 750 ESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGALDYLE 809
E LQ K Q +E +G +E E + L ++ + G +
Sbjct: 1104 EIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQ 1163
Query: 810 PDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKT 869
+L +K F QKL+ +LE A ++ EA+ +A + H D+ E D
Sbjct: 1164 VELNKKREAEF-QKLRRDLEEATLQHEAM-----VAALRKKHADSMAELGEQIDN----- 1212
Query: 870 ALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITK------------EREVSEWKDK 917
R+ ++ + L + DL S AE I+K E +VSE K K
Sbjct: 1213 --LQRVKQKLEKEKSELKMETDDLSS-----NAEAISKAKGNLEKMCRSLEDQVSELKTK 1265
Query: 918 YEESRREVMEM-------RKIVAEYEKTIAQ---MIEDEQREKSVSHQTVQQLVLEKEQA 967
EE +R + ++ + EY + + + ++ R K S Q +++L + E+
Sbjct: 1266 EEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEE 1325
Query: 968 LADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHA 1027
N++ +L + ++E E ++ + L+R + S V + +Y+ +
Sbjct: 1326 TKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQR 1385
Query: 1028 EEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEEL 1080
E+L+ A ++AQ +A++ A A + +LE+T ++ E+E+L
Sbjct: 1386 TEELEEAKKKLAQRLQEAEEHVEAVNA-------KCASLEKTKQRLQNEVEDL 1431
Score = 51.2 bits (121), Expect = 5e-06
Identities = 63/259 (24%), Positives = 117/259 (45%), Gaps = 28/259 (10%)
Query: 839 KLARQIALASRSHQ----DAKREAAHPTDVSISKTALYSRI----GTAEVEKPAGLLFQQ 890
KL+++ +HQ D + E ++ +KT L ++ G+ E EK + ++
Sbjct: 994 KLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLER 1053
Query: 891 PD--LDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQR 948
L+ L++A+ + E + + +K E+ E+ ++++ E A I+ +++
Sbjct: 1054 AKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKE---FEISNLISKIEDEQAVEIQLQKK 1110
Query: 949 EKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQE 1008
K + + +++L E E A EK +DL R E++ E LE E AQ
Sbjct: 1111 IKELQAR-IEELGEEIEAERASRAKAEKQRSDLSRELEEISERLE-----EAGGATSAQV 1164
Query: 1009 YLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALER 1068
L+ KK E +Q L+ EE + A +A +R K H S+ + ++D L+R
Sbjct: 1165 ELN--KKREAEFQKLRRDLEEATLQHEAMVAALRKK-------HADSMAELGEQIDNLQR 1215
Query: 1069 TLEQKNKEIEELTKICDEL 1087
++ KE EL D+L
Sbjct: 1216 VKQKLEKEKSELKMETDDL 1234
Score = 46.6 bits (109), Expect = 1e-04
Identities = 57/289 (19%), Positives = 134/289 (46%), Gaps = 33/289 (11%)
Query: 825 QEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSI-SKTALYSRI------GT 877
++ELE ++ + LK + L +S D+ +A + I +K L ++I
Sbjct: 873 RKELEEKMVTL--LKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAE 930
Query: 878 AEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEK 937
E E A L ++ L+ + +I E +++ + + + +V + + +A ++
Sbjct: 931 EEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE 990
Query: 938 TIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRK 997
TIA++ ++++ + QT+ L E+++ +N + K+ L ++ + ++ LE +K
Sbjct: 991 TIAKLSKEKKALQETHQQTLDDLQAEEDK----VNILTKAKTKLEQQVDDLEGSLEQEKK 1046
Query: 998 NEEVLKRCAQEYLSRVKKEEQRYQAL---KVHAEEKLDRANAEIAQVRGKAQQEQAAH-- 1052
L+R ++ +K ++ + K +EKL++ EI+ + K + EQA
Sbjct: 1047 LRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQ 1106
Query: 1053 -QASLRKEQLRVDALERTLEQK--------------NKEIEELTKICDE 1086
Q +++ Q R++ L +E + ++E+EE+++ +E
Sbjct: 1107 LQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1155
Score = 42.7 bits (99), Expect = 0.002
Identities = 50/220 (22%), Positives = 96/220 (43%), Gaps = 26/220 (11%)
Query: 890 QPDLDSALQIARAEIITKEREVSE-WKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQR 948
Q DL L I + E+ E W + R + ++++ E+ Q++ +
Sbjct: 1667 QEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERV--QLLHTQNT 1724
Query: 949 E----KSVSHQTVQQLVLEKEQALADLNSVE----KSLADLFRRYEKMKEV------LEG 994
K V QL E E+ + + + E K++ D E++K+ LE
Sbjct: 1725 SLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1784
Query: 995 FRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQA 1054
+KN L++ ++ R+ + EQ ALK ++++ + A + ++ G+ + EQ +
Sbjct: 1785 MKKN---LEQTVKDLQHRLDEAEQL--ALK-GGKKQIQKLEARVRELEGEVENEQKRNAE 1838
Query: 1055 S---LRKEQLRVDALERTLEQKNKEIEELTKICDELIAKM 1091
+ LRK + RV L E+ K + L + D+L AK+
Sbjct: 1839 AVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKV 1878
Score = 42.0 bits (97), Expect = 0.003
Identities = 65/294 (22%), Positives = 122/294 (41%), Gaps = 27/294 (9%)
Query: 808 LEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSIS 867
L+ L++ N + + + E + AI R E L+ A++ + EA + S+
Sbjct: 1360 LQRALSKANSEVAQWRTKYETD-AIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLE 1418
Query: 868 KTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREV-- 925
KT R+ EVE L+ ++A + ++ +SEWK KYEE++ E+
Sbjct: 1419 KTK--QRLQN-EVED---LMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEA 1472
Query: 926 ---------MEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQL---VLEKEQALADLNS 973
E+ K+ YE+++ Q +E +RE Q + L + E + + +L
Sbjct: 1473 SQKESRSLSTELFKVKNVYEESLDQ-LETLRRENKNLQQEISDLTEQIAEGGKQIHELEK 1531
Query: 974 VEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDR 1033
++K + + E E ++EE Q L++VK E R A K ++L R
Sbjct: 1532 IKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKR 1591
Query: 1034 ANAEIAQVRGKAQQEQAAHQASLRKEQLRV-DALERTLEQKNKEIEELTKICDE 1086
+ + + Q + R + LRV +E L + ++ ++ E
Sbjct: 1592 NHTRVVE----TMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAE 1641
Score = 39.3 bits (90), Expect = 0.021
Identities = 43/200 (21%), Positives = 88/200 (44%), Gaps = 31/200 (15%)
Query: 903 EIITKEREVSEWKD---KYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQ 959
E+ T + E + KD K E R+E+ E + + + + ++ E + + + +Q
Sbjct: 851 EMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQ 910
Query: 960 LVLEKEQALADLNSV-------EKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSR 1012
L+ K Q A + V E+ A+L + K+++ +K+ + L+ L++
Sbjct: 911 LIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT----LAK 966
Query: 1013 VKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASL---------------- 1056
V+KE+ + + E++ + IA++ + + Q HQ +L
Sbjct: 967 VEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKA 1026
Query: 1057 -RKEQLRVDALERTLEQKNK 1075
K + +VD LE +LEQ+ K
Sbjct: 1027 KTKLEQQVDDLEGSLEQEKK 1046
Score = 37.4 bits (85), Expect = 0.078
Identities = 50/268 (18%), Positives = 117/268 (43%), Gaps = 13/268 (4%)
Query: 821 AQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKTALYSRIGTAEV 880
A LQ E+E +E + +R+IA + + H + S+ T +++
Sbjct: 1681 ANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQL 1740
Query: 881 EKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIA 940
+ + Q+ +A + A+ + IT ++E K +++ + M+K + + K +
Sbjct: 1741 QSEVEEVIQESR--NAEEKAK-KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1797
Query: 941 QMIED-EQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNE 999
+++ EQ + +Q+L + ++ + +K A+ + K + ++
Sbjct: 1798 HRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQT 1857
Query: 1000 EVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRG-KAQQEQAAHQASLRK 1058
E ++ V K + + ++ K AEE +++NA +++ R + + E+A +A + +
Sbjct: 1858 EEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAE 1917
Query: 1059 EQLRVDALERTLEQKNKEIEELTKICDE 1086
Q+ L K++E+ TKI E
Sbjct: 1918 SQV------NKLRVKSREVH--TKISAE 1937
Score = 30.8 bits (68), Expect = 7.3
Identities = 37/202 (18%), Positives = 86/202 (42%), Gaps = 16/202 (7%)
Query: 892 DLDSALQIARAEIITKEREVSEWKD----KYEESRREVMEMRKIVAEYEKTIAQMIEDEQ 947
+ +++L+ +I+ + E+++ K K E E+ ++++ +T+ ++ E
Sbjct: 1549 EAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEI 1608
Query: 948 REKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQ 1007
R ++ + + +++ + + LN + A+ R Y + +L+ + + + R +
Sbjct: 1609 RSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQE 1668
Query: 1008 EYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVD--- 1064
+ ++ E+R L+ EE A E + R + EQ AS R + L
Sbjct: 1669 DLKEQLAIVERRANLLQAEIEELW--ATLEQTE-RSRKIAEQELLDASERVQLLHTQNTS 1725
Query: 1065 ------ALERTLEQKNKEIEEL 1080
LE + Q E+EE+
Sbjct: 1726 LINTKKKLENDVSQLQSEVEEV 1747
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 60.8 bits (146), Expect = 7e-09
Identities = 124/562 (22%), Positives = 192/562 (34%), Gaps = 97/562 (17%)
Query: 100 ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPF 159
E+P++ P P AP PP + + + PPP P R D + +P
Sbjct: 1032 ESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPE 1091
Query: 160 RPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKST 219
P S + K + F P S A +T + T
Sbjct: 1092 APLSSELEPFHPKPKIRTRKSSRMTPF-------------PATSAAPEPHPSTSTAQPVT 1138
Query: 220 DSVPISKSTLSRS----------LSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASST 269
P S++T SR+ + A + ++S+ P V P + T + S+
Sbjct: 1139 PK-PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQP--VTSEPTSQVTRGRKSRSS 1195
Query: 270 LK--RTKKPRPPSLKKKQTTKKPTETPPV-------KETQQEPDEESLVPSGENLASETK 320
+K T P L+ +T +P + P K E +VP+ L T
Sbjct: 1196 VKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTS 1255
Query: 321 TESAKTEGPSPALLE--------ETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNS 372
T+ T P+ +TP EP V P A S S + V P ++
Sbjct: 1256 TDQPVTSEPTYQATRGRKNRSSVKTP-EPVV-PTAPELRPSTSTDRPVTPKPTSRTTRSR 1313
Query: 373 PPVGRKTLPLTTAPEAGEVTPSDSGGQEDSP-AKGLSVRLEFDYSEDK---SSWDNQQEN 428
+ P T P A E+ S S Q +P + R + S K S+ E
Sbjct: 1314 TNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPEL 1373
Query: 429 PPPTKKIGKKPVAKMPLRRP-------KMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTY 481
PP T ++PV P R KTPE L P +P P+ D P+
Sbjct: 1374 PPSTST--EQPVTPEPTSRATRGRKNRSSGKTPETL--VPTAPKLEPSTSTDQPVTP--- 1426
Query: 482 TFDIDKWDDPNFNPFSSTSK---MQESPKLPQQSYNFDPD-----TCDESVDPFKTSSKT 533
P S ++ + S K P+ P+ + D+ V P TS T
Sbjct: 1427 ------------EPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQAT 1474
Query: 534 PSSPSKS---------PASFEIPASAMEANGVDGDGLNKP--AKKKKTPLKTDTFRVKKS 582
+S P + E+ ASA V + ++ +K ++ +KT V +
Sbjct: 1475 RGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAA 1534
Query: 583 PKRSP---LSDPPSQDPTPAAT 601
P+ P P + +PT AT
Sbjct: 1535 PELQPSTSTDQPVTPEPTSRAT 1556
Score = 31.2 bits (69), Expect = 5.6
Identities = 74/346 (21%), Positives = 121/346 (34%), Gaps = 74/346 (21%)
Query: 6 STSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSS--PVADDI------- 56
STS NQ T R+ + N ++K + P +P+ +S+ PV +
Sbjct: 1581 STSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRR 1640
Query: 57 ------------IQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPES 104
++PAA +DLE T S + + Q ++ S P
Sbjct: 1641 KTNRSSVKTPKPVEPAA-SDLEPFTPTDQSVTPEAIAQGGQS----KTLRSSTVRAMPVP 1695
Query: 105 TTPVKAPPAPPPPP--PEVIPEPE-VSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRP 161
TTP P P PE I +P + Q PG S P+ P S +E
Sbjct: 1696 TTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPG--SLAAPIDHKPCSAPLEPKSQAS 1753
Query: 162 PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDT------FQTLEP--RASDAKNQEGKVN 213
+ + AV A S T + + +L++T Q +EP R+ + K +
Sbjct: 1754 RNQRWGAV-----RAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFTPELQPKAS 1808
Query: 214 TRRKST----DSVPISKS-----TLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSS 264
RK + DS P K +++ ++ + D A G E V
Sbjct: 1809 QSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVT---------- 1858
Query: 265 SASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVP 310
P+P K+ Q ++P P + + ++ES P
Sbjct: 1859 -----------PKPGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAP 1893
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 60.5 bits (145), Expect = 9e-09
Identities = 118/536 (22%), Positives = 184/536 (34%), Gaps = 92/536 (17%)
Query: 98 AFETPESTTP---VKAPPAPPPPPPEVIPEP--------EVSTQPPPEEP-GCGSETVPV 145
A TP + P PP P PPP V P V +P E G G T+P
Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP- 71
Query: 146 PDGPRSDSVE--GSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRAS 203
PR+ G+ R P+ P + G N +
Sbjct: 72 ESAPRAGPTRSAGTSSRNPA--------SRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
Query: 204 DAKNQEGKVNTRRKSTDSVPISKSTLS---RSLSLQASDFDGASSSGNPEAVALAPDAYS 260
G+ R + ++V K+T + +LS A + G P + A+A + +
Sbjct: 124 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP-SPAMARRSRA 182
Query: 261 TGSSSASSTLKRTKKPRPPSLKKKQTTKKPTE---TPPVKETQQEPDEESLV--PSGENL 315
G+ + +PRPP+ +++ +E T P ++ P + P+ +L
Sbjct: 183 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
Query: 316 ASE-TKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPP 374
+S T S GPS P P+ PK + + + PP R +P
Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPS-QPK------PKGLQALRPPQVTPPRKDAAPA 295
Query: 375 VGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKK 434
+G PL+++P A TPS S + L P +
Sbjct: 296 LG----PLSSSPLA---TPSPSAALQSQAPPTLPA-------------------TPHSSS 329
Query: 435 IGKKPVAKMPLRRPKMKKTP--EKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPN 492
+ + +PL P P + L + PA+PP P + T++F P
Sbjct: 330 LTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSF----LPSPP 385
Query: 493 FNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAME 552
+P +T Q P L ++ P + P+SP SP + P +
Sbjct: 386 LSPL-ATPPPQAPPAL--------------ALPPLQAPPSPPASPPLSPLATPSPQA--- 427
Query: 553 ANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATP--ETPP 606
N + L P +P F SP SP + PPSQ P A P + PP
Sbjct: 428 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 483
Score = 50.4 bits (119), Expect = 9e-06
Identities = 98/413 (23%), Positives = 139/413 (33%), Gaps = 70/413 (16%)
Query: 214 TRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRT 273
+ +T+ P ++ S LQ SSS P L+ A S SA T +
Sbjct: 213 SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP----LSSPARS--GPSARGTPRAP 266
Query: 274 KKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPAL 333
P P K Q + P TPP K+ S P T + SA + +P
Sbjct: 267 AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA------TPSPSAALQSQAPPT 320
Query: 334 LEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTP 393
L TP ++ + A PL + PP+ ++PP L T P P
Sbjct: 321 LPATPHSSSLTCQLATPLP------LAPPSP------SAPP------SLQTLPSPPATPP 362
Query: 394 SDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKT 453
S + SP L+ +S S PP + P A L P ++
Sbjct: 363 SQATTSLGSPT------LQATHSFLPS--------PPLSPLATPPPQAPPALALPPLQAP 408
Query: 454 PEKLDNTPASPPRSP-AEPN-DIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQ 511
P + PASPP SP A P+ P A + + P P + SP +
Sbjct: 409 P----SPPASPPLSPLATPSPQAPNALAVHLLQAP-FSPPPSPPVQAPFSPPASPPVSPS 463
Query: 512 SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTP 571
+ + P + P+SP SP++ P A L KP +
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP-PPQAPPPLAAPPLQLAKPPPQAPPA 522
Query: 572 LKTDTFRVKKSPKRS----------------PLSDPPSQDPTPAATP--ETPP 606
L T + SP S PL+ PP Q P A P + PP
Sbjct: 523 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 575
Score = 46.2 bits (108), Expect = 2e-04
Identities = 94/424 (22%), Positives = 140/424 (33%), Gaps = 40/424 (9%)
Query: 200 PRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVA------ 253
P A G V + + + I +T+ S +SS NP +
Sbjct: 41 PAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRG 100
Query: 254 -LAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSG 312
AP A +T SS + + RP L +K ET + + P +L
Sbjct: 101 ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALS--- 157
Query: 313 ENLASETKTESAKTEG-PSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQN 371
A + S T G PSPA+ + A G + P + SA PP G + +
Sbjct: 158 ---AGARRDTSGPTPGTPSPAMARRSR---AAGTEVGLPRPAPSARPR-PPTEGPRKSVS 210
Query: 372 SPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPP 431
S T P A PS GG + ++ LS S +S + P
Sbjct: 211 SASEHSTTEPSPAARRR----PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266
Query: 432 TKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDP 491
KP LR P++ TP + D PA P S + P+A + + + P
Sbjct: 267 AHPSQPKPKGLQALRPPQV--TPPRKDAAPALGPLSSS-----PLATPSPSAALQSQAPP 319
Query: 492 NF--NPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPAS 549
P SS+ Q + LP S + PS P+ P+
Sbjct: 320 TLPATPHSSSLTCQLATPLP---------LAPPSPSAPPSLQTLPSPPATPPSQATTSLG 370
Query: 550 AMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVIS 609
+ + P TP + P ++P S P S +P ATP +
Sbjct: 371 SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA 430
Query: 610 AVVH 613
VH
Sbjct: 431 LAVH 434
Score = 42.7 bits (99), Expect = 0.002
Identities = 83/353 (23%), Positives = 113/353 (32%), Gaps = 60/353 (16%)
Query: 18 TPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPADLESPTLAASSYHG 77
TP P + ++ + P SP + S P + + A P P+LAA
Sbjct: 422 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 481
Query: 78 DVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPA----PPPPPPEVIPEPEVSTQPPP 133
S + S A P++ P+ APP PPP P + P + P P
Sbjct: 482 PPSPPASPPM-------SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP 534
Query: 134 EEPGCGSETV-PVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELV 192
G P P S P PP + + P AS
Sbjct: 535 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP------------- 581
Query: 193 DTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLS--LQASDFDGASSSGN-- 248
T Q PR + V+ R + P SRS S L D G SSS
Sbjct: 582 -TLQA--PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 638
Query: 249 ----------PEAVALA---PDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPP 295
PE A A PDA A+ + + P PP L + P PP
Sbjct: 639 PEELRGYDSGPEGGAAASPPPDAELAACHPAAWS----RGPAPP-LAFRGAPGAPLPWPP 693
Query: 296 VKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAA 348
S + L + +TE ++ P+P L+ P G KAA
Sbjct: 694 ATGPG----------SADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA 736
Score = 37.0 bits (84), Expect = 0.10
Identities = 92/404 (22%), Positives = 135/404 (33%), Gaps = 67/404 (16%)
Query: 38 TPGSPDHRDASSSPVADDII---------QPAAPADLESPTLAASSYHGDVVGQVSTDLI 88
TPG+P A S A + +P P + +++++S H +
Sbjct: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA---- 223
Query: 89 AQRSSDSEEAFETP------ESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSET 142
A+R + + P S TP+ +P P P +QP P+ G +
Sbjct: 224 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK--GLQALR 281
Query: 143 VPVPDGPRSDS------VEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQ 196
P PR D+ + SP PS S A P T + + L
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPS--AALQSQAPPTLPATPH----SSSLTCQLA 335
Query: 197 TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAV---- 252
T P A + + + T + P +T S +LQA+ S +P A
Sbjct: 336 TPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 395
Query: 253 ---ALA-PDAYSTGSSSASSTLKRTKKPRPPS-----LKKKQTTKKPTETPPVKETQQEP 303
ALA P + S AS L P P + + Q P +PPV+ P
Sbjct: 396 APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 455
Query: 304 DEESLVPSG-------------------ENLASETKTESAKTEGPSPALLEETPLEPAVG 344
+ PS AS + SA +P L PL+ A
Sbjct: 456 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 515
Query: 345 PKAACP-LDSESAEGVV-PPASGGGRVQNSPPVGRKTLPLTTAP 386
P A P L + + + PPAS G+ SP PL T P
Sbjct: 516 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 559
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 60.5 bits (145), Expect = 9e-09
Identities = 53/199 (26%), Positives = 97/199 (48%), Gaps = 15/199 (7%)
Query: 903 EIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREK-SVSHQTVQQLV 961
E+ +K +E+ + K + ++ E+ E +K + + + Q IE E +EK S +Q Q +
Sbjct: 241 ELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMRE-QQQIEKEIKEKDSELNQKRPQYI 299
Query: 962 LEKEQA---LADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQ 1018
KE + L + +KSL + + Y+K K ++ K +++ QE+ R+++E Q
Sbjct: 300 KAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQ 359
Query: 1019 RY---------QALKVHA-EEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALER 1068
Q K H +E+ + A +AQ K ++Q A Q L E+ + E
Sbjct: 360 SQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEA 419
Query: 1069 TLEQKNKEIEELTKICDEL 1087
++QK +EIEE K ++L
Sbjct: 420 KIKQKLREIEENQKRIEKL 438
Score = 42.7 bits (99), Expect = 0.002
Identities = 45/199 (22%), Positives = 90/199 (45%), Gaps = 18/199 (9%)
Query: 910 EVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALA 969
++ E K++ E +E M+ ++ AE + +Q + R K Q L
Sbjct: 673 KLKEKKERLTEELKEQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRHLALNLQ 732
Query: 970 DLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKE---EQRYQALKVH 1026
+ + +E LA+ R +K +++ + + LK + V +E E + ++
Sbjct: 733 EKSKLESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRNIREF 792
Query: 1027 AEEKLDRANAEIAQVRGKAQQEQAA-------HQASLRKEQLRVDALERTLEQKNKEIEE 1079
EEK+ R N EIA+ R + + ++ + L+++Q +V E+T+++ EIE+
Sbjct: 793 EEEKVKRQN-EIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEK 851
Query: 1080 L-------TKICDELIAKM 1091
L KI DE +A++
Sbjct: 852 LKKEEQRHMKIIDETMAQL 870
Score = 41.6 bits (96), Expect = 0.004
Identities = 43/206 (20%), Positives = 90/206 (43%), Gaps = 29/206 (14%)
Query: 897 LQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQT 956
L+ A+ + ++ + K +E +E++ + K E+E+ + + + + R+ ++
Sbjct: 312 LEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQ 371
Query: 957 VQQLVLEKEQA----------LADLNSVEKSLADLFRRYEKMK-----EVLEGFRKNEEV 1001
V++ KE+A L N +K+ D E+ K ++ + R+ EE
Sbjct: 372 VKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEEN 431
Query: 1002 LKRC--AQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKE 1059
KR +EY++ K+ + + L+ E+++ A I ++ + Q E
Sbjct: 432 QKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVM---------E 482
Query: 1060 QL---RVDALERTLEQKNKEIEELTK 1082
QL R+D E + +Q+ EI E K
Sbjct: 483 QLGDARIDRQESSRQQRKAEIMESIK 508
Score = 40.8 bits (94), Expect = 0.007
Identities = 62/279 (22%), Positives = 121/279 (43%), Gaps = 40/279 (14%)
Query: 822 QKLQEELEFAIMRIEALKLARQIA----LASRSHQDAKREAAHPTDVSISKTALYSRIGT 877
++L EEL+ E +K R+ A + S++H R +D+ +KT R
Sbjct: 679 ERLTEELK------EQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDLEQTKT----RHLA 728
Query: 878 AEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVME-------MRK 930
+++ + L + + + + I ++ERE+ + K+K + EV E +R
Sbjct: 729 LNLQEKSKLESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRN 788
Query: 931 IVAEYEKTIAQMIEDEQREKSVSHQTVQ---QLVLEKEQALADLNSVEKSLADLFRRYEK 987
I E+ + + E ++ +Q + QL EK Q D + V + +K
Sbjct: 789 IREFEEEKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHM----WEQTVKK 844
Query: 988 MKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGK--A 1045
+ +E +K E+ + E +++++ + ++ A K +K N E+ ++R K
Sbjct: 845 DENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDK----NHEMEEIRKKLGG 900
Query: 1046 QQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKIC 1084
++ H L+KE V A+E LEQK + L + C
Sbjct: 901 ANKEMTH---LQKE---VTAIETKLEQKRSDRHNLLQAC 933
Score = 37.0 bits (84), Expect = 0.10
Identities = 44/205 (21%), Positives = 87/205 (42%), Gaps = 13/205 (6%)
Query: 894 DSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSV- 952
DS L R + I + S K E +++ + +K Y+K M E E+ SV
Sbjct: 288 DSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQK---HYKKRKGDMDELEKEMLSVE 344
Query: 953 -SHQTVQQLVLEKEQALA-DLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYL 1010
+ Q ++ + E+ Q+ DL E + R E+ + + E R +
Sbjct: 345 KARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQ 404
Query: 1011 SRVKKEEQRYQALKVHAEEKLDRANAEIAQVR---GKAQQEQAAHQASLRKEQLRVDALE 1067
R+ EE++ KV E K+ + EI + + K ++ + SL +++ L
Sbjct: 405 DRLDLEERK----KVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELT 460
Query: 1068 RTLEQKNKEIEELTKICDELIAKMG 1092
+E + I+E+ K ++++ ++G
Sbjct: 461 EEVEMAKRRIDEINKELNQVMEQLG 485
Score = 34.3 bits (77), Expect = 0.66
Identities = 38/160 (23%), Positives = 72/160 (45%), Gaps = 11/160 (6%)
Query: 934 EYEKTIAQM-IEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVL 992
EY + + ++ I + R V V+ + ++ + L +L + Y+K K+ +
Sbjct: 116 EYSEELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEM 175
Query: 993 ----EGFRKNEEVLKRCAQEY--LSRVKKEEQRYQALK---VHAEEKLDRANAEIAQVR- 1042
E + N K A E + K+E RYQ LK V A+ +L +V
Sbjct: 176 VKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEI 235
Query: 1043 GKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTK 1082
K +E A+ + K++ R+D +E L++K KE+ ++ +
Sbjct: 236 EKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMR 275
Score = 30.4 bits (67), Expect = 9.6
Identities = 46/178 (25%), Positives = 76/178 (42%), Gaps = 25/178 (14%)
Query: 936 EKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYE----KMKEV 991
++T A++I E ++++ VQ + E + L L + K+ L + MK
Sbjct: 91 DRTFARVIVGGSSEYKINNKVVQ--LHEYSEELEKLGILIKARNFLVFQGAVESIAMKNP 148
Query: 992 LEGFRKNEEVLK--RCAQEYLSR----VKKEEQR----YQALKVHAEEKLDRANAEIAQV 1041
E EE+ + AQEY R VK EE ++ + AE K + E A
Sbjct: 149 KERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADR 208
Query: 1042 RGKAQQEQAAHQASLR-----KEQLRVDALERTLEQKNKEIEE----LTKICDELIAK 1090
+ + E Q L+ ++ ++ L + L KNKEIE+ + K+ DEL K
Sbjct: 209 YQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEK 266
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 59.3 bits (142), Expect = 2e-08
Identities = 60/276 (21%), Positives = 116/276 (42%), Gaps = 39/276 (14%)
Query: 836 EALKLARQIALASRSHQDAKREAAHPTDVSISKTALYSRI----------GTAEVEKPAG 885
++ L Q+ SR ++D K E D + T R G+ ++K
Sbjct: 1231 DSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQH 1290
Query: 886 L------LFQQPDLDSA-----LQIARAEIITKEREVSEWKDKYEESRREVME----MRK 930
L + QQ D+A L+ A I K +E+ K +++E + E + K
Sbjct: 1291 LEIELKQVMQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSK 1350
Query: 931 IVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKE 990
+ Y++ I + + E +++ T+ QL ++KE+ D + + +L R + E
Sbjct: 1351 VRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEE---DTSGYRAQIDNLTRENRSLSE 1407
Query: 991 VLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQA 1050
++ + E L RV+++ Q+ +A ++ + E+ QV +E
Sbjct: 1408 EIKRLKNTLTQ----TTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESV 1463
Query: 1051 AHQASLRKEQLRVDALERTLEQKNKEIEELTKICDE 1086
++ SL D +T++ KNKEIE L ++ D+
Sbjct: 1464 RYKQSL-------DDAAKTIQDKNKEIERLKQLIDK 1492
Score = 51.2 bits (121), Expect = 5e-06
Identities = 53/216 (24%), Positives = 107/216 (49%), Gaps = 24/216 (11%)
Query: 892 DLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKS 951
D ++ LQ + ++ +E +K + +E+ +R +YE+ ++Q + ++ +
Sbjct: 1502 DENARLQRVQYDLQKANSSATETINKLKVQEQELTRLR---IDYER-VSQERTVKDQDIT 1557
Query: 952 VSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKN--EEVLK----RC 1005
++++L L+K++ +LN ++++ ++ + +K++E LEG R++ E+ +K
Sbjct: 1558 RFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQ 1617
Query: 1006 AQEYLSRVKKE-----EQRYQALKVHAEEK------LDRANAEIAQVRGKAQQEQ-AAHQ 1053
E S VKK Q+ L H EK L R ++E+ +R + QEQ + Q
Sbjct: 1618 QLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQ 1677
Query: 1054 ASLRKE--QLRVDALERTLEQKNKEIEELTKICDEL 1087
A LR E Q ++ R+L + EIE L + + L
Sbjct: 1678 AHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENL 1713
Score = 39.3 bits (90), Expect = 0.021
Identities = 58/257 (22%), Positives = 107/257 (41%), Gaps = 37/257 (14%)
Query: 819 LFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKTALYSRIGTA 878
L + L E E +R+E L R RS D+ + A T + + S T
Sbjct: 1713 LTKEHLMLEEELRNLRLEYDDLRR-----GRSEADSDKNA---TILELRSQLQISNNRTL 1764
Query: 879 EVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESR---------REVMEMR 929
E++ GL+ DL + R EI +++ E ++ +ES+ RE + ++
Sbjct: 1765 ELQ---GLI---NDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVK 1818
Query: 930 KIVAEYEKTIAQMIEDE-QREKSVSH---QTVQQLVLEKEQALADLNSVEKSLADLFRRY 985
V E +K Q +EDE R KS + Q+L EK+Q DLN + +Y
Sbjct: 1819 IKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWK-------TQY 1871
Query: 986 EKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKA 1045
+ +E + E +R S +++ + + ++ KL+ + E + +
Sbjct: 1872 SRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRE---TQSQL 1928
Query: 1046 QQEQAAHQASLRKEQLR 1062
+ E++ +Q + K + R
Sbjct: 1929 ETERSRYQREIDKLRQR 1945
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 58.9 bits (141), Expect = 3e-08
Identities = 100/448 (22%), Positives = 147/448 (32%), Gaps = 68/448 (15%)
Query: 66 ESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEP 125
E P A++ H D A R S EE P S P P P +P P
Sbjct: 972 EGPVTPATTVHAPE----EPDTAAVRVSTPEE----PASPAAAVPTPEEPTSPAAAVPTP 1023
Query: 126 EVSTQP-----PPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSG 180
E T P PPEEP + VP P+ P S + P+ +AV ++P + +
Sbjct: 1024 EEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1083
Query: 181 TYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDF 240
V T + EP + A + T + P ++ + ++
Sbjct: 1084 A----------VPTPE--EPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPA 1131
Query: 241 DGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQ 300
A++ PE A A T SAS+ + P E
Sbjct: 1132 SPAAAVPTPEEPAFPAPAVPTPEESASAAV----------------------AVPTPEES 1169
Query: 301 QEPDEESLVPSGENLASETKTESAKTEGPSPALLEETP------LEPAVGPKAACPLDSE 354
P + VP+ AS + E SPA TP LE P A+ P E
Sbjct: 1170 ASP--AAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEE 1227
Query: 355 SAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFD 414
A + A SP TL T+ A +TP E+ + SV +
Sbjct: 1228 PAS--LAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTP------EELSSPAASVPTPEE 1279
Query: 415 YSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDI 474
+ ++ N +E P + VA +P + P A PP P +
Sbjct: 1280 PASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVP--AIPAAAVPPMEEVSPIGV 1337
Query: 475 P---IAKGTYTFDIDKWDDPNFNPFSST 499
P ++ T + I + P SST
Sbjct: 1338 PFLGVSAHTDSVPISEEGTPVLEEASST 1365
Score = 47.8 bits (112), Expect = 6e-05
Identities = 88/400 (22%), Positives = 145/400 (36%), Gaps = 50/400 (12%)
Query: 248 NPEAVALA-------PDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQ 300
+PE ALA D G + ++T+ ++P +++ T ++P T
Sbjct: 952 SPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVS-TPEEPASPAAAVPTP 1010
Query: 301 QEPDEESL-VPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSE--SAE 357
+EP + VP+ E S E SPA TP EP P AA P E S
Sbjct: 1011 EEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEP-TSPAAAVPTPEEPTSPA 1069
Query: 358 GVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSE 417
VP SP T T+P A TP E+ + +V + +
Sbjct: 1070 AAVPTP----EEPTSPAAAVPTPEEPTSPAAAVPTP------EEPTSPAAAVPTPEEPAS 1119
Query: 418 DKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPP-----RSPAEPN 472
++ +E P + P + P TPE+ + + P SPA
Sbjct: 1120 PAAAVPTPEEPASPAAAV---PTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAV 1176
Query: 473 DIPIAKGTYTFDIDKWDDPNF------NPFSSTSKMQESPKLPQQSYNFDPDTCDESVDP 526
P ++ + ++P P + + ++E P S + S+
Sbjct: 1177 PTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTS-PAASVPTSEEPA--SLAA 1233
Query: 527 FKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRS 586
++ + P+SP+ + + E P S+ A + + L+ PA TP + + S
Sbjct: 1234 AVSNPEEPTSPAAAVPTLEEPTSSAAA-VLTPEELSSPAASVPTPEEPASPAAAVSNLEE 1292
Query: 587 PLSDPPSQDPTP---------AATPETPPVISAVVHATDE 617
P S P + PTP TPE P + +A V +E
Sbjct: 1293 PAS-PAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEE 1331
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.124 0.342
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,995,055
Number of Sequences: 37866
Number of extensions: 2985904
Number of successful extensions: 35265
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 485
Number of HSP's successfully gapped in prelim test: 1902
Number of HSP's that attempted gapping in prelim test: 16742
Number of HSP's gapped (non-prelim): 12597
length of query: 1094
length of database: 18,247,518
effective HSP length: 113
effective length of query: 981
effective length of database: 13,968,660
effective search space: 13703255460
effective search space used: 13703255460
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.