Guide to the Human Genome
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Search of human proteins with 45827698

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45827698 disco-interacting protein 2A isoform d [Homo
sapiens]
         (812 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45827698 disco-interacting protein 2A isoform d [Homo sapiens]    1623   0.0  
gi|45827692 disco-interacting protein 2A isoform a [Homo sapiens]    1596   0.0  
gi|45827696 disco-interacting protein 2A isoform c [Homo sapiens]    1596   0.0  
gi|45827694 disco-interacting protein 2A isoform b [Homo sapiens]    1596   0.0  
gi|225735629 disco-interacting protein 2A isoform g [Homo sapiens]   1582   0.0  
gi|225735627 disco-interacting protein 2A isoform f [Homo sapiens]   1489   0.0  
gi|225735625 disco-interacting protein 2A isoform e [Homo sapiens]   1415   0.0  
gi|44888818 DIP2 disco-interacting protein 2 homolog C [Homo sap...  1060   0.0  
gi|55749758 DIP2 disco-interacting protein 2 homolog B [Homo sap...  1030   0.0  
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              48   3e-05
gi|91982772 mucin 17 [Homo sapiens]                                    44   8e-04
gi|116284392 mucin 2 precursor [Homo sapiens]                          43   0.001
gi|153792110 HEG homolog 1 [Homo sapiens]                              42   0.002
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                41   0.005
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                41   0.005
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                41   0.005
gi|20070107 orthodenticle homeobox 1 [Homo sapiens]                    40   0.011
gi|111120318 NK6 transcription factor related, locus 1 [Homo sap...    38   0.043
gi|22035606 mitogen-activated protein kinase kinase kinase kinas...    38   0.043
gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 ...    38   0.043
gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens]                     38   0.043
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    37   0.056
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo...    37   0.056
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]              37   0.073
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]              37   0.073
gi|66529407 tensin [Homo sapiens]                                      37   0.073
gi|20270323 zinc finger protein 653 [Homo sapiens]                     37   0.073
gi|112421108 capicua homolog [Homo sapiens]                            37   0.096
gi|83367077 mucin 16 [Homo sapiens]                                    36   0.13 
gi|57546899 myeloid/lymphoid or mixed-lineage leukemia transloca...    36   0.16 

>gi|45827698 disco-interacting protein 2A isoform d [Homo sapiens]
          Length = 812

 Score = 1623 bits (4202), Expect = 0.0
 Identities = 812/812 (100%), Positives = 812/812 (100%)

Query: 1   MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60
           MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL
Sbjct: 1   MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60

Query: 61  QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRR 120
           QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRR
Sbjct: 61  QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRR 120

Query: 121 SVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA 180
           SVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA
Sbjct: 121 SVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA 180

Query: 181 SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERP 240
           SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERP
Sbjct: 181 SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERP 240

Query: 241 QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELL 300
           QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELL
Sbjct: 241 QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELL 300

Query: 301 EVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGK 360
           EVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGK
Sbjct: 301 EVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGK 360

Query: 361 AVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLL 420
           AVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLL
Sbjct: 361 AVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLL 420

Query: 421 AELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPP 480
           AELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPP
Sbjct: 421 AELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPP 480

Query: 481 LSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALT 540
           LSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALT
Sbjct: 481 LSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALT 540

Query: 541 QACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYK 600
           QACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYK
Sbjct: 541 QACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYK 600

Query: 601 ARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRP 660
           ARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRP
Sbjct: 601 ARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRP 660

Query: 661 EVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVG 720
           EVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVG
Sbjct: 661 EVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVG 720

Query: 721 QVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGA 780
           QVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGA
Sbjct: 721 QVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGA 780

Query: 781 PIFDRPFTRTGLLGFIGPVSMSSCTSTGSQRR 812
           PIFDRPFTRTGLLGFIGPVSMSSCTSTGSQRR
Sbjct: 781 PIFDRPFTRTGLLGFIGPVSMSSCTSTGSQRR 812


>gi|45827692 disco-interacting protein 2A isoform a [Homo sapiens]
          Length = 1571

 Score = 1596 bits (4133), Expect = 0.0
 Identities = 798/798 (100%), Positives = 798/798 (100%)

Query: 1   MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60
           MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL
Sbjct: 1   MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60

Query: 61  QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRR 120
           QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRR
Sbjct: 61  QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRR 120

Query: 121 SVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA 180
           SVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA
Sbjct: 121 SVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA 180

Query: 181 SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERP 240
           SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERP
Sbjct: 181 SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERP 240

Query: 241 QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELL 300
           QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELL
Sbjct: 241 QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELL 300

Query: 301 EVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGK 360
           EVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGK
Sbjct: 301 EVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGK 360

Query: 361 AVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLL 420
           AVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLL
Sbjct: 361 AVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLL 420

Query: 421 AELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPP 480
           AELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPP
Sbjct: 421 AELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPP 480

Query: 481 LSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALT 540
           LSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALT
Sbjct: 481 LSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALT 540

Query: 541 QACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYK 600
           QACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYK
Sbjct: 541 QACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYK 600

Query: 601 ARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRP 660
           ARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRP
Sbjct: 601 ARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRP 660

Query: 661 EVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVG 720
           EVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVG
Sbjct: 661 EVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVG 720

Query: 721 QVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGA 780
           QVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGA
Sbjct: 721 QVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGA 780

Query: 781 PIFDRPFTRTGLLGFIGP 798
           PIFDRPFTRTGLLGFIGP
Sbjct: 781 PIFDRPFTRTGLLGFIGP 798



 Score =  115 bits (289), Expect = 1e-25
 Identities = 137/527 (25%), Positives = 206/527 (39%), Gaps = 64/527 (12%)

Query: 305  PDPNQPKPEGSETSVLRGEPLTAGV------------------PRPPSLLATLQRWGT-T 345
            P P Q +PE    S++ G  L AG                    R    LA + +W   T
Sbjct: 939  PKPRQKQPEVGPASMIVGN-LVAGKRIAQASGRELAHLEDSDQARKFLFLADVLQWRAHT 997

Query: 346  QPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPN 405
             P  P    L+  G    T T  +L  R+ ++A  L+ K        L  GD VALV+P 
Sbjct: 998  TPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAALMEK------GRLSVGDHVALVYPP 1051

Query: 406  SDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFL-------ALTTD 458
               V  + AFYGCL    VPV +  P        Q +G  L +  + +        LTT 
Sbjct: 1052 G--VDLIAAFYGCLYCGCVPVTVRPP------HPQNLGTTLPTVKMIVEVSKSACVLTTQ 1103

Query: 459  ACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSK 518
            A  + L   +       + WP +  L  D     K    + P + D     AY+++  S 
Sbjct: 1104 AVTRLLRSKEAAAAVDIRTWPTI--LDTDDIPKKKIASVFRPPSPDV---LAYLDFSVST 1158

Query: 519  EGSTVGVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVV 578
             G   GV +SHA+  A CR++   C    +  +   LD     G     L SV +    V
Sbjct: 1159 TGILAGVKMSHAATSALCRSIKLQCELYPSRQIAICLDPYCGLGFALWCLCSVYSGHQSV 1218

Query: 579  SVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW---SLLAQRG---QRDVSLSSLRML 632
             VP   +++N   W+  V  YKAR        M      L AQ G    + V+LS +R  
Sbjct: 1219 LVPPLELESNVSLWLSAVSQYKARVTFCSYSVMEMCTKGLGAQTGVLRMKGVNLSCVRTC 1278

Query: 633  IVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAV 692
            +V     P  I+   +F  +F+  GL    +         + + ++      GP P    
Sbjct: 1279 MVVAEERP-RIALTQSFSKLFKDLGLPARAVSTTFGCRVNVAICLQ---GTAGPDPTTVY 1334

Query: 693  LSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSS 752
            + M  L +  +R+        L + + G+++PG  V +   E T        +GEI VSS
Sbjct: 1335 VDMRALRHDRVRLVERGSPHSLPLMESGKILPGVKVIIAHTE-TKGPLGDSHLGEIWVSS 1393

Query: 753  SATGTAYYGLLG---ITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFI 796
                T YY + G   +  + F A  ++ G        + RTG LGF+
Sbjct: 1394 PHNATGYYTVYGEEALHADHFSA-RLSFGDTQTI---WARTGYLGFL 1436


>gi|45827696 disco-interacting protein 2A isoform c [Homo sapiens]
          Length = 841

 Score = 1596 bits (4133), Expect = 0.0
 Identities = 798/798 (100%), Positives = 798/798 (100%)

Query: 1   MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60
           MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL
Sbjct: 1   MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60

Query: 61  QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRR 120
           QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRR
Sbjct: 61  QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRR 120

Query: 121 SVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA 180
           SVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA
Sbjct: 121 SVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA 180

Query: 181 SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERP 240
           SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERP
Sbjct: 181 SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERP 240

Query: 241 QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELL 300
           QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELL
Sbjct: 241 QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELL 300

Query: 301 EVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGK 360
           EVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGK
Sbjct: 301 EVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGK 360

Query: 361 AVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLL 420
           AVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLL
Sbjct: 361 AVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLL 420

Query: 421 AELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPP 480
           AELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPP
Sbjct: 421 AELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPP 480

Query: 481 LSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALT 540
           LSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALT
Sbjct: 481 LSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALT 540

Query: 541 QACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYK 600
           QACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYK
Sbjct: 541 QACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYK 600

Query: 601 ARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRP 660
           ARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRP
Sbjct: 601 ARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRP 660

Query: 661 EVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVG 720
           EVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVG
Sbjct: 661 EVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVG 720

Query: 721 QVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGA 780
           QVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGA
Sbjct: 721 QVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGA 780

Query: 781 PIFDRPFTRTGLLGFIGP 798
           PIFDRPFTRTGLLGFIGP
Sbjct: 781 PIFDRPFTRTGLLGFIGP 798


>gi|45827694 disco-interacting protein 2A isoform b [Homo sapiens]
          Length = 889

 Score = 1596 bits (4133), Expect = 0.0
 Identities = 798/798 (100%), Positives = 798/798 (100%)

Query: 1   MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60
           MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL
Sbjct: 1   MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60

Query: 61  QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRR 120
           QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRR
Sbjct: 61  QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRR 120

Query: 121 SVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA 180
           SVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA
Sbjct: 121 SVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA 180

Query: 181 SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERP 240
           SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERP
Sbjct: 181 SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERP 240

Query: 241 QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELL 300
           QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELL
Sbjct: 241 QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELL 300

Query: 301 EVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGK 360
           EVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGK
Sbjct: 301 EVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGK 360

Query: 361 AVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLL 420
           AVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLL
Sbjct: 361 AVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLL 420

Query: 421 AELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPP 480
           AELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPP
Sbjct: 421 AELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPP 480

Query: 481 LSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALT 540
           LSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALT
Sbjct: 481 LSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALT 540

Query: 541 QACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYK 600
           QACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYK
Sbjct: 541 QACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYK 600

Query: 601 ARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRP 660
           ARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRP
Sbjct: 601 ARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRP 660

Query: 661 EVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVG 720
           EVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVG
Sbjct: 661 EVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVG 720

Query: 721 QVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGA 780
           QVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGA
Sbjct: 721 QVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGA 780

Query: 781 PIFDRPFTRTGLLGFIGP 798
           PIFDRPFTRTGLLGFIGP
Sbjct: 781 PIFDRPFTRTGLLGFIGP 798


>gi|225735629 disco-interacting protein 2A isoform g [Homo sapiens]
          Length = 1567

 Score = 1582 bits (4097), Expect = 0.0
 Identities = 794/798 (99%), Positives = 794/798 (99%), Gaps = 4/798 (0%)

Query: 1   MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60
           MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL
Sbjct: 1   MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60

Query: 61  QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRR 120
           QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRR
Sbjct: 61  QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRR 120

Query: 121 SVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA 180
           SVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA
Sbjct: 121 SVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA 180

Query: 181 SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERP 240
           SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERP
Sbjct: 181 SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERP 240

Query: 241 QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELL 300
           QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELL
Sbjct: 241 QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELL 300

Query: 301 EVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGK 360
           E    DPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGK
Sbjct: 301 E----DPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGK 356

Query: 361 AVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLL 420
           AVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLL
Sbjct: 357 AVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLL 416

Query: 421 AELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPP 480
           AELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPP
Sbjct: 417 AELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPP 476

Query: 481 LSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALT 540
           LSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALT
Sbjct: 477 LSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALT 536

Query: 541 QACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYK 600
           QACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYK
Sbjct: 537 QACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYK 596

Query: 601 ARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRP 660
           ARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRP
Sbjct: 597 ARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRP 656

Query: 661 EVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVG 720
           EVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVG
Sbjct: 657 EVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVG 716

Query: 721 QVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGA 780
           QVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGA
Sbjct: 717 QVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGA 776

Query: 781 PIFDRPFTRTGLLGFIGP 798
           PIFDRPFTRTGLLGFIGP
Sbjct: 777 PIFDRPFTRTGLLGFIGP 794



 Score =  115 bits (289), Expect = 1e-25
 Identities = 137/527 (25%), Positives = 206/527 (39%), Gaps = 64/527 (12%)

Query: 305  PDPNQPKPEGSETSVLRGEPLTAGV------------------PRPPSLLATLQRWGT-T 345
            P P Q +PE    S++ G  L AG                    R    LA + +W   T
Sbjct: 935  PKPRQKQPEVGPASMIVGN-LVAGKRIAQASGRELAHLEDSDQARKFLFLADVLQWRAHT 993

Query: 346  QPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPN 405
             P  P    L+  G    T T  +L  R+ ++A  L+ K        L  GD VALV+P 
Sbjct: 994  TPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAALMEK------GRLSVGDHVALVYPP 1047

Query: 406  SDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFL-------ALTTD 458
               V  + AFYGCL    VPV +  P        Q +G  L +  + +        LTT 
Sbjct: 1048 G--VDLIAAFYGCLYCGCVPVTVRPP------HPQNLGTTLPTVKMIVEVSKSACVLTTQ 1099

Query: 459  ACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSK 518
            A  + L   +       + WP +  L  D     K    + P + D     AY+++  S 
Sbjct: 1100 AVTRLLRSKEAAAAVDIRTWPTI--LDTDDIPKKKIASVFRPPSPDV---LAYLDFSVST 1154

Query: 519  EGSTVGVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVV 578
             G   GV +SHA+  A CR++   C    +  +   LD     G     L SV +    V
Sbjct: 1155 TGILAGVKMSHAATSALCRSIKLQCELYPSRQIAICLDPYCGLGFALWCLCSVYSGHQSV 1214

Query: 579  SVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW---SLLAQRG---QRDVSLSSLRML 632
             VP   +++N   W+  V  YKAR        M      L AQ G    + V+LS +R  
Sbjct: 1215 LVPPLELESNVSLWLSAVSQYKARVTFCSYSVMEMCTKGLGAQTGVLRMKGVNLSCVRTC 1274

Query: 633  IVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAV 692
            +V     P  I+   +F  +F+  GL    +         + + ++      GP P    
Sbjct: 1275 MVVAEERP-RIALTQSFSKLFKDLGLPARAVSTTFGCRVNVAICLQ---GTAGPDPTTVY 1330

Query: 693  LSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSS 752
            + M  L +  +R+        L + + G+++PG  V +   E T        +GEI VSS
Sbjct: 1331 VDMRALRHDRVRLVERGSPHSLPLMESGKILPGVKVIIAHTE-TKGPLGDSHLGEIWVSS 1389

Query: 753  SATGTAYYGLLG---ITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFI 796
                T YY + G   +  + F A  ++ G        + RTG LGF+
Sbjct: 1390 PHNATGYYTVYGEEALHADHFSA-RLSFGDTQTI---WARTGYLGFL 1432


>gi|225735627 disco-interacting protein 2A isoform f [Homo sapiens]
          Length = 798

 Score = 1489 bits (3854), Expect = 0.0
 Identities = 755/798 (94%), Positives = 755/798 (94%), Gaps = 43/798 (5%)

Query: 1   MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60
           MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL
Sbjct: 1   MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60

Query: 61  QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRR 120
           QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRR
Sbjct: 61  QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRR 120

Query: 121 SVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA 180
           SVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA
Sbjct: 121 SVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA 180

Query: 181 SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERP 240
           SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHI                      
Sbjct: 181 SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHI---------------------- 218

Query: 241 QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELL 300
                                GVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELL
Sbjct: 219 ---------------------GVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELL 257

Query: 301 EVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGK 360
           EVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGK
Sbjct: 258 EVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGK 317

Query: 361 AVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLL 420
           AVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLL
Sbjct: 318 AVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLL 377

Query: 421 AELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPP 480
           AELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPP
Sbjct: 378 AELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPP 437

Query: 481 LSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALT 540
           LSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALT
Sbjct: 438 LSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALT 497

Query: 541 QACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYK 600
           QACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYK
Sbjct: 498 QACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYK 557

Query: 601 ARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRP 660
           ARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRP
Sbjct: 558 ARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRP 617

Query: 661 EVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVG 720
           EVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVG
Sbjct: 618 EVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVG 677

Query: 721 QVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGA 780
           QVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGA
Sbjct: 678 QVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGA 737

Query: 781 PIFDRPFTRTGLLGFIGP 798
           PIFDRPFTRTGLLGFIGP
Sbjct: 738 PIFDRPFTRTGLLGFIGP 755


>gi|225735625 disco-interacting protein 2A isoform e [Homo sapiens]
          Length = 1110

 Score = 1415 bits (3664), Expect = 0.0
 Identities = 709/725 (97%), Positives = 712/725 (98%), Gaps = 1/725 (0%)

Query: 75  AAPKQQKSRPTASRDE-RFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP 133
           AAP   + R + +  E     DVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP
Sbjct: 10  AAPLPAEVRESLAELELELSEDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTP 69

Query: 134 PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT 193
           PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT
Sbjct: 70  PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT 129

Query: 194 APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS 253
           APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS
Sbjct: 130 APSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCS 189

Query: 254 GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE 313
           GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE
Sbjct: 190 GSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPE 249

Query: 314 GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR 373
           GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR
Sbjct: 250 GSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSR 309

Query: 374 SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT 433
           SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT
Sbjct: 310 SLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLT 369

Query: 434 RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK 493
           RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK
Sbjct: 370 RKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAK 429

Query: 494 PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN 553
           PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN
Sbjct: 430 PPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTN 489

Query: 554 VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW 613
           VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW
Sbjct: 490 VLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMHW 549

Query: 614 SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL 673
           SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL
Sbjct: 550 SLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEAL 609

Query: 674 TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL 733
           TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL
Sbjct: 610 TVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKL 669

Query: 734 EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL 793
           EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL
Sbjct: 670 EGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLL 729

Query: 794 GFIGP 798
           GFIGP
Sbjct: 730 GFIGP 734



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 66/247 (26%), Positives = 93/247 (37%), Gaps = 46/247 (18%)

Query: 305  PDPNQPKPEGSETSVLRGEPLTAGV------------------PRPPSLLATLQRWGT-T 345
            P P Q +PE    S++ G  L AG                    R    LA + +W   T
Sbjct: 875  PKPRQKQPEVGPASMIVGN-LVAGKRIAQASGRELAHLEDSDQARKFLFLADVLQWRAHT 933

Query: 346  QPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPN 405
             P  P    L+  G    T T  +L  R+ ++A  L+ K        L  GD VALV+P 
Sbjct: 934  TPDHPLFLLLNAKGTVTSTATCVQLHKRAERVAAALMEK------GRLSVGDHVALVYPP 987

Query: 406  SDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFL-------ALTTD 458
               V  + AFYGCL    VPV +  P        Q +G  L +  + +        LTT 
Sbjct: 988  G--VDLIAAFYGCLYCGCVPVTVRPP------HPQNLGTTLPTVKMIVEVSKSACVLTTQ 1039

Query: 459  ACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSK 518
            A  + L   +       + WP +  L  D     K    + P + D     AY+++  S 
Sbjct: 1040 AVTRLLRSKEAAAAVDIRTWPTI--LDTDDIPKKKIASVFRPPSPDV---LAYLDFSVST 1094

Query: 519  EGSTVGV 525
             G   GV
Sbjct: 1095 TGILAGV 1101


>gi|44888818 DIP2 disco-interacting protein 2 homolog C [Homo
           sapiens]
          Length = 1556

 Score = 1060 bits (2740), Expect = 0.0
 Identities = 529/802 (65%), Positives = 632/802 (78%), Gaps = 23/802 (2%)

Query: 1   MADRGCPLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSL 60
           MADR   LE   LP EVR  LAELELELSEGDITQKGYEKKR+KL+  Y+P    +D +L
Sbjct: 1   MADRS--LEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVDQAL 58

Query: 61  QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKM--PMPSK 118
             E R P    T ++A +  + R + SRDER+RSDVHTEAVQAALAK+KERKM  PMPSK
Sbjct: 59  PQERRAP---VTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSK 115

Query: 119 RRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSS 178
           RRS++V +S++ YTPPDTSS SEDEGS++   + T T  Q   ++E W+ + I GS+TS 
Sbjct: 116 RRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTS- 174

Query: 179 SASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSY-F 237
                        TT+ S+  + G+ A   LA + A THI+ HSAPPDVTT   EHS   
Sbjct: 175 -------------TTSSSSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQV 221

Query: 238 ERPQVAS-VRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDF 296
           ERPQ ++  R+ P+  +  ++ET DGVPV+SRVS+KIQQL+NTLKRPKRPPL+EFFVDDF
Sbjct: 222 ERPQGSTGSRTAPKYGNAELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDF 281

Query: 297 EELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALD 356
           EELLEVQQPDPNQPKPEG++   +RGE L      PPSL A LQRWGT  PK+PCLT +D
Sbjct: 282 EELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMD 341

Query: 357 TTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNSDPVMFMVAFY 416
           T GK +Y LTYGKLW+RS+K+AY++L+KL +K EP+++PGDRVALVFPN+DP  FM AFY
Sbjct: 342 TNGKPLYILTYGKLWTRSMKVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFY 401

Query: 417 GCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPKAQTGEVAAFK 476
           GCLLAE+VPVPIEVPLTRKDAGSQQ+GFLLGSCGV +ALT+DAC KGLPK+ TGE+  FK
Sbjct: 402 GCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFK 461

Query: 477 GWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTVGVTVSHASLLAQC 536
           GWP L W V + KHL+KPP+DW P  +D    TAYIEYKT K+GS +GVTV+  +LL  C
Sbjct: 462 GWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHC 521

Query: 537 RALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLSWIQKV 596
           +ALTQACGY+EAET+ NVLDFK+D GLWHG+LTSVMN MHV+S+PY+LMK NPLSWIQKV
Sbjct: 522 QALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKV 581

Query: 597 CFYKARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSR 656
           C YKA+ A VKSRDMHW+L+A R QRD++LSSLRMLIVADGANPWSISSCDAFLNVFQS+
Sbjct: 582 CQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSK 641

Query: 657 GLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTV 716
           GLR EVICPCASSPEALTVAIRRP D    PP + VLSM+GL+YGVIRVD+EEKLSVLTV
Sbjct: 642 GLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTV 701

Query: 717 QDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFEAVPVT 776
           QDVG VMPGA +C VK +G P LC+TDE+GE+CV + ATGT+YYGL G+TKN FE  P+T
Sbjct: 702 QDVGLVMPGAIMCSVKPDGVPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMT 761

Query: 777 TGGAPIFDRPFTRTGLLGFIGP 798
           + GAPI + PF RTGLLGF+GP
Sbjct: 762 SSGAPISEYPFIRTGLLGFVGP 783



 Score =  114 bits (285), Expect = 4e-25
 Identities = 126/522 (24%), Positives = 206/522 (39%), Gaps = 54/522 (10%)

Query: 305  PDPNQPKPEGSETSVLRGEPLTA-----------------GVPRPPSLLATLQRW-GTTQ 346
            P P Q +PE    SV+ G  ++                     R    L+ + +W   T 
Sbjct: 924  PKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTT 983

Query: 347  PKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPNS 406
            P     T L+  G    +LT  +L  R+ K+A  L+ +        L+ GD VALV+P  
Sbjct: 984  PDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMER------GHLQDGDHVALVYPPG 1037

Query: 407  DPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGS-QQVGFLLGSCGVFLALTTDACQKGLP 465
              +  + AFYGCL A  VP+ +  P  +  A +   V  ++        +TT    K L 
Sbjct: 1038 --IDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLR 1095

Query: 466  KAQTGEVAAFKGWPPLSWLVIDGKHLAK--PPKDWHPLAQDTGTGTAYIEYKTSKEGSTV 523
              +       + WP    L++D   L K  P +   P   DT    AY+++  S  G   
Sbjct: 1096 SREAAAAVDVRTWP----LILDTDDLPKKRPAQICKPCNPDT---LAYLDFSVSTTGMLA 1148

Query: 524  GVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYA 583
            GV +SHA+  A CR++   C    +  +   LD     G     L SV +    + +P +
Sbjct: 1149 GVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPS 1208

Query: 584  LMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQ------RDVSLSSLRMLIVADG 637
             ++ NP  W+  V  YK R        M         Q      R + LS +R  +V   
Sbjct: 1209 ELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAE 1268

Query: 638  ANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNG 697
              P  I+   +F  +F+  GL P  +         L + ++      GP P    + M  
Sbjct: 1269 ERP-RIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQ---GTSGPDPTTVYVDMRA 1324

Query: 698  LSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGT 757
            L +  +R+        L + + G+++PG  + +   E T        +GEI V S+   +
Sbjct: 1325 LRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPE-TKGPLGDSHLGEIWVHSAHNAS 1383

Query: 758  AYYGLLG---ITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFI 796
             Y+ + G   +  + F +  ++ G        + RTG LGF+
Sbjct: 1384 GYFTIYGDESLQSDHFNS-RLSFGDTQTI---WARTGYLGFL 1421


>gi|55749758 DIP2 disco-interacting protein 2 homolog B [Homo
           sapiens]
          Length = 1576

 Score = 1030 bits (2664), Expect = 0.0
 Identities = 522/818 (63%), Positives = 628/818 (76%), Gaps = 30/818 (3%)

Query: 1   MADRGC---PLEAAPLPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGID 57
           MA+RG    P   A LP EVR  LAELELELSEGDITQKGYEKKR+KLL+ Y P  Q  D
Sbjct: 1   MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETD 60

Query: 58  PSLQAE--NRIPGPSQTTAAAP-KQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKM- 113
            ++Q E  N+ P PS    +AP K  ++R   +RDER+RSD+HTEAVQAALAK+KE+KM 
Sbjct: 61  SAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMA 120

Query: 114 -PMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQ 172
            PMP+KRRS  V S  +  TPPDTSSASEDEGSLRR   L++   QS  + E W++R IQ
Sbjct: 121 LPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ 180

Query: 173 GSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTT--- 229
           GSSTSSSASST SH   + T+              +LA + A+T I+  SAPPDVTT   
Sbjct: 181 GSSTSSSASSTLSHGEVKGTSG-------------SLADVFANTRIENFSAPPDVTTTTS 227

Query: 230 -----GLVEHSYFERPQVASVRSVPRGCS-GSMLETADGVPVNSRVSSKIQQLLNTLKRP 283
                  +  +  + P    V+ + +G +  S+++TADGVPV+SRVS+KIQQLLNTLKRP
Sbjct: 228 SSSSSSSIRPANIDLPPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTKIQQLLNTLKRP 287

Query: 284 KRPPLKEFFVDDFEELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWG 343
           KRPPLKEFFVDD EE++EV QPDPNQPKPEG + + ++GEPL      PP+L + LQRWG
Sbjct: 288 KRPPLKEFFVDDSEEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWG 347

Query: 344 TTQPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVF 403
           TTQ K  CLTALD TGK VYTLTYGKLWSRSLKLAYTLLNKL +KNEP+LKPGDRVALV+
Sbjct: 348 TTQAKCSCLTALDMTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVY 407

Query: 404 PNSDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKG 463
           PN+DPVMFMVAFYGCLLAE++PVPIEVPLTRKDAG QQ+GFLLGSCG+ LALT++ C KG
Sbjct: 408 PNNDPVMFMVAFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEVCLKG 467

Query: 464 LPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTGTAYIEYKTSKEGSTV 523
           LPK Q GE+  FKGWP L W+V D K+L+KPPKDW P     GT  AYIEYKTSKEGS +
Sbjct: 468 LPKTQNGEIVQFKGWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVM 527

Query: 524 GVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYA 583
           GVTVS  ++L+ C+AL+QAC YSE ET+ NVLDFK+DAGLWHG+  +VMN+MH +SVPY+
Sbjct: 528 GVTVSRLAMLSHCQALSQACNYSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYS 587

Query: 584 LMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSI 643
           +MK  PLSW+Q+V  +KA+ ALVK RD+HW+++A R QRDVSLSSLRMLIV DGANPWS+
Sbjct: 588 VMKTCPLSWVQRVHAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSV 647

Query: 644 SSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVI 703
           SSCDAFL++FQS GL+PE ICPCA+S EA+TVAIRRP   G P P +A+LSMNGLSYGVI
Sbjct: 648 SSCDAFLSLFQSHGLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVI 707

Query: 704 RVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLL 763
           RV+TE+K S LTVQDVG VMPG  +C+VK +G P LCKTDE+GEICVSS   G  Y+GL 
Sbjct: 708 RVNTEDKNSALTVQDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLA 767

Query: 764 GITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPVSM 801
           G+TKN FE +PV + G+P+ D PF R+GLLGF+GP S+
Sbjct: 768 GVTKNTFEVIPVNSAGSPVGDVPFIRSGLLGFVGPGSL 805



 Score =  108 bits (271), Expect = 2e-23
 Identities = 123/529 (23%), Positives = 201/529 (37%), Gaps = 49/529 (9%)

Query: 305  PDPNQPKPEGSETSVLRGEPLTAG------------------VPRPPSLLATLQRW-GTT 345
            P P Q +P     SV+ G  L AG                  + R    LA + +W    
Sbjct: 943  PKPRQKQPGVGPASVMVGN-LVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQA 1001

Query: 346  QPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDRVALVFPN 405
             P       L+  G  V T +  +L  R+ ++A  L +K        L  GD V L++P 
Sbjct: 1002 TPDHVLFMLLNAKGTTVCTASCLQLHKRAERIASVLGDK------GHLNAGDNVVLLYPP 1055

Query: 406  SDPVMFMVAFYGCLLAELVPVPIEVPLTRK-DAGSQQVGFLLGSCGVFLALTTDACQKGL 464
               +  + AFYGCL A  +PV +  P  +   A    V  ++        LT+    + L
Sbjct: 1056 G--IELIAAFYGCLYAGCIPVTVRPPHAQNLTATLPTVRMIVDVSKAACILTSQTLMRLL 1113

Query: 465  PKAQTGEVAAFKGWPPLSWLVIDGKHLAKP--PKDWHPLAQDTGTGTAYIEYKTSKEGST 522
               +       K WP     +ID   L +   P+ + P    T    AY+++  S  G  
Sbjct: 1114 RSREAAAAVDVKTWPT----IIDTDDLPRKRLPQLYKP---PTPEMLAYLDFSVSTTGML 1166

Query: 523  VGVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPY 582
             GV +SH+++ A CRA+   C    +  +   LD     G     L SV +    V +P 
Sbjct: 1167 TGVKMSHSAVNALCRAIKLQCELYSSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLIPP 1226

Query: 583  ALMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQ------RDVSLSSLRMLIVAD 636
              ++ N   W+  V  YK R        M         Q      R ++LS +R  +V  
Sbjct: 1227 MELENNLFLWLSTVNQYKIRDTFCSYSVMELCTKGLGNQVEVLKTRGINLSCVRTCVVVA 1286

Query: 637  GANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMN 696
               P  ++   +F  +F+  GL P  +     S   + + ++      GP P    + + 
Sbjct: 1287 EERP-RVALQQSFSKLFKDIGLSPRAVSTTFGSRVNVAICLQ---GTSGPDPTTVYVDLK 1342

Query: 697  GLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATG 756
             L +  +R+        L + + G+++PG  V +V  E T        +GEI V+S  T 
Sbjct: 1343 SLRHDRVRLVERGAPQSLLLSESGKILPGVKVVIVNPE-TKGPVGDSHLGEIWVNSPHTA 1401

Query: 757  TAYYGLLGITKNVFEAVPVTTGGAPIFDRPFTRTGLLGFIGPVSMSSCT 805
            + YY +        +               + RTG LGF+    +++ T
Sbjct: 1402 SGYYTIYDSETLQADHFNTRLSFGDAAQTLWARTGYLGFVRRTELTAAT 1450


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 54/223 (24%), Positives = 87/223 (39%), Gaps = 36/223 (16%)

Query: 14  PAEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSLQAENRIPGPSQTT 73
           PA    SL+ L  +  + +   +G E+     + R  PL+ G+  S  +E     PS  T
Sbjct: 574 PASPALSLSSLRSDDLQAETQGQGTEQATGAAVTRE-PLVLGLSCSWDSEGASSTPSTCT 632

Query: 74  AAAPKQQKSRPTAS-------------------RDERFRSDVHTEAVQAALAKYKERKMP 114
           ++   Q++ R  AS                   R   +R D H+      L     +++P
Sbjct: 633 SSQQGQRRHRSRASAMSSPSSPGLGRVAPRGHPRHSHYRKDTHSP-----LDSSVTKQVP 687

Query: 115 MPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGS 174
            P +RR      SV  Y+   +S+ ++  G+LR P           S   P  D +   S
Sbjct: 688 RPPERRRACQDGSVPRYSGSSSSTRTQASGNLRPPS----------SGSLPSQDLLGTSS 737

Query: 175 STSSSASSTSSHPGGRPTTAPSAA-ATPGAAATTALAGLEAHT 216
           +T + A  +    G  P  APSA  A    + T + A +  HT
Sbjct: 738 ATVTPAVHSDFVSGVSPHNAPSAGWAGDAGSRTCSPAPIPPHT 780


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 57/244 (23%), Positives = 94/244 (38%), Gaps = 45/244 (18%)

Query: 66   IPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKE-----RKMPMPSKRR 120
            +  P  +T +      + P  +  E   S    E      + Y E     R MP+ +K  
Sbjct: 2527 VASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPL 2586

Query: 121  SVLVHSSVETYTPPDTS---SASEDEGSLRRPGRLTSTPLQSHSSVEPWLD--------- 168
            +    S++ T TP DTS   + S +  S     + TS P+ + S V   L          
Sbjct: 2587 ASSEASTLST-TPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPV 2645

Query: 169  ---------------RVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGA---AATTALA 210
                           R +  +ST +S+S T++     PT+ P   +TP      +TT LA
Sbjct: 2646 ASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLA 2705

Query: 211  GLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCSGSMLETADG-VPVNSRV 269
              EA T   L + P D +T +   +     + +S  +   G S  +   +DG  P+ S +
Sbjct: 2706 NSEAST---LSTTPVDTSTPVTTSA-----EASSSPTTAEGTSMRISTPSDGSTPLTSIL 2757

Query: 270  SSKI 273
             S +
Sbjct: 2758 VSTL 2761



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 58/239 (24%), Positives = 93/239 (38%), Gaps = 30/239 (12%)

Query: 67   PGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHS 126
            P  + T      Q  S P  +      +  ++E     L        P+ S   S L  +
Sbjct: 3305 PADTSTPVTTYSQASSSPPIADGTSMPTSTYSEG-STPLTNMSFSTTPVVSSEASTLSTT 3363

Query: 127  SVETYTPPDTSS----------------ASEDEGSLRRPGR-LTSTPLQSHS----SVEP 165
             V+T TP  TS+                +S  EG+       +++TP+ S      S  P
Sbjct: 3364 PVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTP 3423

Query: 166  WLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGA---AATTALAGLEAHTHIDLHS 222
                 +  +ST +S+S T +     PT+  S  +TP +    +TT +A  EA T   L +
Sbjct: 3424 VDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEAST---LST 3480

Query: 223  APPDVTTGLVEHS-YFERPQVASVRSVPRGCSGSMLETADGVPVNSR-VSSKIQQLLNT 279
             P D +T +   S     P  A V S+P   +G        +PV++  V+S     L+T
Sbjct: 3481 TPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLST 3539



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 44/213 (20%), Positives = 76/213 (35%), Gaps = 35/213 (16%)

Query: 66   IPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVH 125
            +  P  +T +      + P  +  E   S + TE      + Y +R+ P+ S   S  V 
Sbjct: 2114 VASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVV 2173

Query: 126  SSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSS 185
            +S    T                   L++TP+ + + V          +ST + +S T+S
Sbjct: 2174 ASSAIST-------------------LSTTPVDTSTPVT---------NSTEARSSPTTS 2205

Query: 186  HPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHS-YFERPQVAS 244
                 PT+ PS  +TP  +   +   +       L + P D +T +   +     P  A 
Sbjct: 2206 EGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAE 2265

Query: 245  VRSVPRGCSGSMLETADGVPV------NSRVSS 271
              S+P             +PV      NS VS+
Sbjct: 2266 GTSIPTSTLSEGTTPLTSIPVSHTLVANSEVST 2298



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 57/215 (26%), Positives = 84/215 (39%), Gaps = 30/215 (13%)

Query: 72   TTAAAPKQQKSRPTASRDERFRSDVHTEAVQA-ALAKYKERKMPMPSKRRSVLVHSSVET 130
            T   A  +  +  T   D R       EA  +   A+     +  P +RR+ L   SV T
Sbjct: 2937 TVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVST 2996

Query: 131  YTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGR 190
                    AS +  +L R    TSTP+ +               ST +S+S T++   G 
Sbjct: 2997 MPV-----ASSEASTLSRTPADTSTPVTT---------------STEASSSPTTAEGTGI 3036

Query: 191  PTTAPSAAATPGAA---ATTALAGLEAHTHIDLHSAPPDVTTGLVEHS-YFERPQVASVR 246
            P + PS  +TP  +   +TT +A  EA T   L + P D  + +V  +     P  A   
Sbjct: 3037 PISTPSEGSTPLTSIPVSTTPVAIPEAST---LSTTPVDSNSPVVTSTEVSSSPTPAEGT 3093

Query: 247  SVPRGCSGSMLETADGVPVNSR--VSSKIQQLLNT 279
            S+P            GVPV++    SS I  L  T
Sbjct: 3094 SMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTT 3128



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 48/207 (23%), Positives = 76/207 (36%), Gaps = 28/207 (13%)

Query: 67   PGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHS 126
            P  + T      +  S PT S      +   +E     L       M + S   S L  +
Sbjct: 3129 PVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEG-STPLTYMPVSTMLVVSSEDSTLSAT 3187

Query: 127  SVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHS--------------------SVEPW 166
             V+T TP  TS+ +    +       TSTP +  +                    S  P 
Sbjct: 3188 PVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPV 3247

Query: 167  LDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAA---ATTALAGLEAHTHIDLHSA 223
                   +ST +S+S  ++     PT+ PS  +TP  +   +TT +A  E  T   L + 
Sbjct: 3248 DSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETST---LSTT 3304

Query: 224  PPDVTTGLVEHSY-FERPQVASVRSVP 249
            P D +T +  +S     P +A   S+P
Sbjct: 3305 PADTSTPVTTYSQASSSPPIADGTSMP 3331



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 51/213 (23%), Positives = 84/213 (39%), Gaps = 56/213 (26%)

Query: 66  IPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVH 125
           IP  S+T      +  S PT + D    +                     PS+  + L  
Sbjct: 416 IPVDSKTFVTTASEASSSPTTAEDTSIATST-------------------PSEGSTPLTS 456

Query: 126 SSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSS 185
             V T TP  +S AS           L++TP+ S + V          +ST +S+S  ++
Sbjct: 457 MPVST-TPVASSEASN----------LSTTPVDSKTQVT---------TSTEASSSPPTA 496

Query: 186 HPGGRPTTAPSAAATP---GAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQV 242
                PT+ PS  +TP    + +T  +A  EA T   L + P D +T +   S     + 
Sbjct: 497 EVNSMPTSTPSEGSTPLTSMSVSTMPVASSEAST---LSTTPVDTSTPVTTSS-----EA 548

Query: 243 ASVRSVPRGCSGSMLETADG------VPVNSRV 269
           +S  + P G S      ++G      +PV++R+
Sbjct: 549 SSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRL 581



 Score = 38.5 bits (88), Expect = 0.025
 Identities = 47/172 (27%), Positives = 72/172 (41%), Gaps = 23/172 (13%)

Query: 128  VETYTPPDTSSASEDEGSL------RRPGRLTSTPLQ---------SHSSVEPWLDRVIQ 172
            V TY+   +SS + D  S+           LTS P+          S  S  P    +  
Sbjct: 1073 VTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPV 1132

Query: 173  GSSTSSSASSTSSHPGGRPTTAPSAAATPGAA---ATTALAGLEAHTHIDLHSAPPDVTT 229
             +ST +S+S T++     PT+ PS   TP A+   +TT +   EA+T   L + P D  T
Sbjct: 1133 TTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANT---LSTTPVDSKT 1189

Query: 230  GLVEHSYFER-PQVASVRSVPRGCSGSMLETADGVPV-NSRVSSKIQQLLNT 279
             +   +     P  A V S+P    G        +PV ++ V+S     L+T
Sbjct: 1190 QVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLST 1241



 Score = 37.0 bits (84), Expect = 0.073
 Identities = 45/187 (24%), Positives = 69/187 (36%), Gaps = 28/187 (14%)

Query: 67  PGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHS 126
           P  S+T      +  S P  +      +   +E     L       MP+ S   S L  +
Sbjct: 476 PVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEG-STPLTSMSVSTMPVASSEASTLSTT 534

Query: 127 SVETYTPPDTSSASEDEGSLRRPGRL-TSTPLQ--------------------SHSSVEP 165
            V+T TP  TSS +    +      + TSTP +                    S +S  P
Sbjct: 535 PVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTP 594

Query: 166 WLDRVIQGSSTSSSASSTSSHPGGRPTTAPS---AAATPGAAATTALAGLEAHTHIDLHS 222
                   +S+ +S+SST++     PT+  S      T  + +TT +A  EA T   L +
Sbjct: 595 ADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEAST---LST 651

Query: 223 APPDVTT 229
            P D  T
Sbjct: 652 TPVDSNT 658



 Score = 36.6 bits (83), Expect = 0.096
 Identities = 58/285 (20%), Positives = 98/285 (34%), Gaps = 52/285 (18%)

Query: 51   PLIQGIDPSLQAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKE 110
            PL+  I  S+     +  P  +T +      + P  +  E   S    E      + Y E
Sbjct: 806  PLLTSIPVSITP---VTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSE 862

Query: 111  RKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRV 170
             + P+ S   S  + +         TS+ S           L++TP+ + + V       
Sbjct: 863  GRTPLTSMPVSTTLVA---------TSAIST----------LSTTPVDTSTPVT------ 897

Query: 171  IQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAA---ATTALAGLEAHTHIDLHSAPPDV 227
               +ST + +S T+S     PT+ P   +TP  +   +TT +   EA T   L + P D 
Sbjct: 898  ---NSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEART---LSATPVDT 951

Query: 228  TTGLVEHS-YFERPQVASVRSVPRGCSGSMLETADGVPV-NSRVSSKIQQLLNTLKRPKR 285
            +T +   +     P  A   S+P              PV ++ V++     L+T      
Sbjct: 952  STPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSN 1011

Query: 286  PPLKEFFVDDFEELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVP 330
             PL                 + + P P    TS+    P     P
Sbjct: 1012 TPL-------------TTSTEASSPPPTAEGTSMPTSTPSEGSTP 1043



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 44/205 (21%), Positives = 74/205 (36%), Gaps = 35/205 (17%)

Query: 66   IPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVH 125
            +  P  +T +      + P  +  E   S    E      + Y E + P+          
Sbjct: 1643 VASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPL---------- 1692

Query: 126  SSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSS 185
            +S+   T P  SSA            L++TP+ + + V          +ST + +S T+S
Sbjct: 1693 TSITVRTTPVASSAIST---------LSTTPVDNSTPVT---------TSTEARSSPTTS 1734

Query: 186  HPGGRPTTAPSAAATPGAA---ATTALAGLEAHTHIDLHSAPPDVTTGLVEHS-YFERPQ 241
                 P + PS   TP  +   +TT +   EA T   L + P D +T +   +     P 
Sbjct: 1735 EGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEAST---LSATPIDTSTPVTTSTEATSSPT 1791

Query: 242  VASVRSVPRGCSGSMLETADGVPVN 266
             A   S+P       +      PV+
Sbjct: 1792 TAEGTSIPTSTLSEGMTPLTSTPVS 1816



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 48/228 (21%), Positives = 81/228 (35%), Gaps = 36/228 (15%)

Query: 66   IPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVH 125
            +  P  +T          P  + +E   S    E      + Y E + P+ S        
Sbjct: 1290 VTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTS-------- 1341

Query: 126  SSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSS 185
                   P +T+  +    S+     L++TP+ + + V          +ST + +S T+S
Sbjct: 1342 ------IPVNTTLVASSAISI-----LSTTPVDNSTPVT---------TSTEACSSPTTS 1381

Query: 186  HPGGRPTTAPSAAATPGAA---ATTALAGLEAHTHIDLHSAPPDVTT-GLVEHSYFERPQ 241
                 P + PS   TP  +   +TT +   EA T   L + P D +T G         P 
Sbjct: 1382 EGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEAST---LSATPVDTSTPGTTSAEATSSPT 1438

Query: 242  VASVRSVPRGCSGSMLETADGVPV-NSRVSSKIQQLLNTLKRPKRPPL 288
             A   S+P             +PV N+ V++     L+T       P+
Sbjct: 1439 TAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPV 1486



 Score = 35.0 bits (79), Expect = 0.28
 Identities = 51/198 (25%), Positives = 74/198 (37%), Gaps = 38/198 (19%)

Query: 66  IPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVH 125
           +   + TT+  P    +  T S  E   S    E      + Y ER   + S   S  + 
Sbjct: 583 VSSEASTTSTTPADSNTFVTTS-SEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLV 641

Query: 126 SSVE----TYTPPD-----------TSSASEDEGSLRRPGRLT--STPLQSHS------- 161
           +S E    + TP D           TSS++  EG+       T  STPL S         
Sbjct: 642 ASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVA 701

Query: 162 -------SVEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAA---ATTALAG 211
                  S  P        +ST +S+S T++     PT+ PS  +TP  +   + T L  
Sbjct: 702 SSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTS 761

Query: 212 LEAHTHIDLHSAPPDVTT 229
            EA T   L + P D +T
Sbjct: 762 SEAST---LSTTPLDTST 776



 Score = 35.0 bits (79), Expect = 0.28
 Identities = 40/181 (22%), Positives = 67/181 (37%), Gaps = 20/181 (11%)

Query: 59   SLQAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSK 118
            S   E R P  S + +  P       T SR     S   T + +A+ +       P  ++
Sbjct: 2980 STPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSS-------PTTAE 3032

Query: 119  RRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSS 178
               + + +  E  TP  +   S    ++     L++TP+ S+S V          +ST  
Sbjct: 3033 GTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVV---------TSTEV 3083

Query: 179  SASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPD----VTTGLVEH 234
            S+S T +     P +  S  +TP      +   + +     L + P D    VTT    H
Sbjct: 3084 SSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAH 3143

Query: 235  S 235
            S
Sbjct: 3144 S 3144



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 59/238 (24%), Positives = 94/238 (39%), Gaps = 23/238 (9%)

Query: 62  AENRIPGPSQTTAAAPK---QQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSK 118
           A   IP  + T A++     +  S PT++  E       T A    +A  +   + +   
Sbjct: 300 AATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPV 359

Query: 119 RRSVLVHSSVETYTPPDTSSASE------DEGSLRRPGRLTSTPLQSHS-----SVEPWL 167
             S LV +S E  + P T+ A+        EGS        ST L + S     S  P  
Sbjct: 360 DTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVD 419

Query: 168 DRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAA---ATTALAGLEAHTHIDLHSAP 224
            +    +++ +S+S T++      T+ PS  +TP  +   +TT +A  EA    +L + P
Sbjct: 420 SKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEAS---NLSTTP 476

Query: 225 PDVTTGLVEHS-YFERPQVASVRSVPRG--CSGSMLETADGVPVNSRVSSKIQQLLNT 279
            D  T +   +     P  A V S+P      GS   T+  V      SS+   L  T
Sbjct: 477 VDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTT 534



 Score = 33.5 bits (75), Expect = 0.81
 Identities = 48/198 (24%), Positives = 74/198 (37%), Gaps = 40/198 (20%)

Query: 56   IDPSLQAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPM 115
            +D S+         S  T A   +  S PT++  E              L        P+
Sbjct: 2776 VDTSIPVTTSTEASSSPTTA---EVTSMPTSTPSE----------TSTPLTSMPVNHTPV 2822

Query: 116  PSKRRSVLVHSSVETYTPPDTSS----------------ASEDEGS-LRRPGRLTSTPLQ 158
             S     L  + V+T TP  TS+                ++  EGS L     +++TP+ 
Sbjct: 2823 ASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVA 2882

Query: 159  SHS----SVEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAA---ATTALAG 211
            S      S  P    +   +ST  S+S T++     P + PS  +TP  +   +T  +AG
Sbjct: 2883 SSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAG 2942

Query: 212  LEAHTHIDLHSAPPDVTT 229
             EA T   L + P D  T
Sbjct: 2943 SEAST---LSTTPVDTRT 2957



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 43/166 (25%), Positives = 62/166 (37%), Gaps = 45/166 (27%)

Query: 67   PGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHS 126
            P  + T      Q  S PT + D    +  ++E     L       MP+ S   S   HS
Sbjct: 2362 PADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEG-STPLTSVPVSTMPVVSSEAST--HS 2418

Query: 127  SVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSH 186
            +    TP DTS                 TP+ +               ST +S+S T++ 
Sbjct: 2419 T----TPVDTS-----------------TPVTT---------------STEASSSPTTAE 2442

Query: 187  PGGRPTTAPSAAATPGAA---ATTALAGLEAHTHIDLHSAPPDVTT 229
                PT+ PS   TP A+   +TT +   EA T   L + P D +T
Sbjct: 2443 GTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGT---LSTTPVDTST 2485



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 57/227 (25%), Positives = 84/227 (37%), Gaps = 24/227 (10%)

Query: 70   SQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVE 129
            S TTA    +  S PT++  ER     +       LA  +   +       S  V +S E
Sbjct: 2673 SPTTA----EGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAE 2728

Query: 130  TYTPPDTSSASE------DEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGS-----STSS 178
              + P T+  +        +GS      L ST   + S         +  S     ST +
Sbjct: 2729 ASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEA 2788

Query: 179  SASSTSSHPGGRPTTAPSAAATPGAAAT---TALAGLEAHTHIDLHSAPPDVTTGLVEHS 235
            S+S T++     PT+ PS  +TP  +     T +A  EA T   L + P D +T +   +
Sbjct: 2789 SSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGT---LSTTPVDTSTPVTTST 2845

Query: 236  -YFERPQVASVRSVP--RGCSGSMLETADGVPVNSRVSSKIQQLLNT 279
                 P  A    VP      GS L T+  V      SS+   L  T
Sbjct: 2846 KASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTT 2892



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 49/223 (21%), Positives = 82/223 (36%), Gaps = 20/223 (8%)

Query: 50   IPLIQGIDPSLQAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYK 109
            IP+   I  S+  E   PG +    + P       T+S  + F +   T AV   +    
Sbjct: 3918 IPVATTISVSVITEGSTPGTTIFIPSTPV------TSSTADVFPAT--TGAVSTPVITST 3969

Query: 110  ERKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDR 169
            E   P  S   +    S+ + +T P  ++A+           LT   + +  S      R
Sbjct: 3970 ELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAP----------LTYVTMSTAPSTPRTTSR 4019

Query: 170  VIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTT 229
                S+++ SA+ST  H     TT P   ++  +  +T  +     T    HS+ P  T+
Sbjct: 4020 GCTTSASTLSATSTP-HTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTS 4078

Query: 230  GLVEHSYFERPQVASVRSVPRGCSGSM-LETADGVPVNSRVSS 271
                    E     + R+ P   + S    T   VP N+ + S
Sbjct: 4079 ASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKS 4121



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 48/189 (25%), Positives = 77/189 (40%), Gaps = 34/189 (17%)

Query: 69   PSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAA-LAKYKERKMPMPSKRRSVLVHSS 127
            P  TT  A  +  +  T   D       +++A  +  +A          S+  + L + S
Sbjct: 3287 PVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMS 3346

Query: 128  VETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHP 187
              T TP  +S AS           L++TP+ + + V          +ST +S S T++  
Sbjct: 3347 FST-TPVVSSEAST----------LSTTPVDTSTPVT---------TSTEASLSPTTAEG 3386

Query: 188  GGRPTTAPSAAATPGAA---ATTALAGLEAHTHIDLHSAPPD----VTTGLVEHSYFERP 240
               PT++PS   TP A+   +TT +   E +T   L + P D    VTT     S    P
Sbjct: 3387 TSIPTSSPSEGTTPLASMPVSTTPVVSSEVNT---LSTTPVDSNTLVTTSTEASS---SP 3440

Query: 241  QVASVRSVP 249
             +A   S+P
Sbjct: 3441 TIAEGTSLP 3449



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 45/208 (21%), Positives = 76/208 (36%), Gaps = 28/208 (13%)

Query: 53   IQGIDPSLQAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERK 112
            IQ   PS +       P  TT     +  +  T   D + +    TEA  +A A+     
Sbjct: 2034 IQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMT 2093

Query: 113  MPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQ 172
            +  PS+   +L      T  P  T+  +  E S      L++TP+ S+S V         
Sbjct: 2094 ISAPSEGSPLL------TSIPLSTTPVASPEAS-----TLSTTPVDSNSPVI-------- 2134

Query: 173  GSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLV 232
             +ST  S+S   +      T+  S   TP  +   +   + +     L + P D +T + 
Sbjct: 2135 -TSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVT 2193

Query: 233  EHSYFERPQVASVRSVPRGCSGSMLETA 260
              +          RS P    G+ + T+
Sbjct: 2194 NST--------EARSSPTTSEGTSMPTS 2213



 Score = 30.8 bits (68), Expect = 5.3
 Identities = 39/156 (25%), Positives = 62/156 (39%), Gaps = 27/156 (17%)

Query: 128  VETYTPPDTSSASEDEGSLRRPGR------LTSTPLQSHSSVEPWLDRVIQGSSTSSSAS 181
            V TY+   +S  + D  S+  P        LTS PL +   V      +      +S+ +
Sbjct: 1957 VTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPA 2016

Query: 182  STSSHPGGRPTTA---------PSAAATPGA---AATTALAGLEAHTHIDLHSAPPDVTT 229
            +TS+     PTTA         PS   TP A    +TT +   E +T   L + P D  T
Sbjct: 2017 TTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNT---LSTTPVDSKT 2073

Query: 230  GLVEHSYFERPQVASVRSVPRGCSGSMLETADGVPV 265
             +   +       AS  +   G S ++   ++G P+
Sbjct: 2074 QVTNST------EASSSATAEGSSMTISAPSEGSPL 2103


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 54/239 (22%), Positives = 87/239 (36%), Gaps = 44/239 (18%)

Query: 127  SVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSH 186
            ++ T TPP T++ S        P   T+TP  + +   P    +   +ST++   +T+  
Sbjct: 1590 TITTTTPPPTTTPSP-------PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1642

Query: 187  PGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVR 246
            P    TT P    TP    TT  +       I   + PP  TT             + + 
Sbjct: 1643 PPPTTTTTPPPTTTPSPPTTTTPS-----PPITTTTTPPPTTT-----------PSSPIT 1686

Query: 247  SVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPD 306
            + P   + +M   +     +S +++       T   P  PP              +  P 
Sbjct: 1687 TTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSP--PPTT------------MTTPS 1732

Query: 307  PNQ-PKPEGSETSVL----RGEPLTAGVPRPPSLLA-TLQRWGTTQPKSPCLTALDTTG 359
            P   P P  +  + L       PLT   P PPS+   T   + TT P +PC+   + TG
Sbjct: 1733 PTTTPSPPTTTMTTLPPTTTSSPLTT-TPLPPSITPPTFSPFSTTTPTTPCVPLCNWTG 1790



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 64/306 (20%), Positives = 97/306 (31%), Gaps = 27/306 (8%)

Query: 58   PSLQAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPS 117
            PS       P P+ TT   P    S PT +      +   +  +            P P+
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTT-------PPPT 1451

Query: 118  KRRSVLVHSSVE---TYTP-PDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQG 173
               S  + ++     T TP P T++ S    +   P   T+TP  + +   P    +   
Sbjct: 1452 TTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP 1511

Query: 174  SSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHI--DLHSAPPDVTTGL 231
            +ST++   +T+  P    TT P    TP    TT +    + T +      +PP  TT  
Sbjct: 1512 ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT 1571

Query: 232  VEHSYFERPQVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEF 291
               +    P   +  S P   + +   T    P  +           T   P   P    
Sbjct: 1572 PPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTT---------TTTTPPPTTTPSPPT 1622

Query: 292  FVDDFEELLEVQQPDPNQPKPEGSETS----VLRGEPLTAGVPRPPSLLATLQRWGTTQP 347
                         P    P P  + T+         P T   P PP +  T     TT P
Sbjct: 1623 TTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP-ITTTTTPPPTTTP 1681

Query: 348  KSPCLT 353
             SP  T
Sbjct: 1682 SSPITT 1687



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 27/108 (25%), Positives = 43/108 (39%), Gaps = 4/108 (3%)

Query: 126  SSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSS 185
            +  +T  P  TS+A   E +   P   +STP  S S+  P  +     S+   +   TS+
Sbjct: 4191 TGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTST 4250

Query: 186  HPGGRP----TTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTT 229
             P   P    TT+     +P  + TT+  G          S+ P  +T
Sbjct: 4251 APPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPST 4298


>gi|153792110 HEG homolog 1 [Homo sapiens]
          Length = 1381

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 58/257 (22%), Positives = 95/257 (36%), Gaps = 38/257 (14%)

Query: 87  SRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSL 146
           S    + S  H +  ++ ++ Y + +   PS    VL  S++ +YTP           ++
Sbjct: 593 SSHSEYSSFFHAQTERSNISSY-DGEYAQPSTESPVLHTSNLPSYTP-----------TI 640

Query: 147 RRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAAT------ 200
             P   TS  L +        D      S+SSS+SS+SS   G P   PS + +      
Sbjct: 641 NMPN--TSVVLDT--------DAEFVSDSSSSSSSSSSSSSSGPPLPLPSVSQSHHLFSS 690

Query: 201 --PGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCSGSMLE 258
             P   A+  L    +       S+P  +   L   +    P   S  ++P+  S  +L 
Sbjct: 691 ILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTST--SAPLSVSQTTLPQSSSTPVLP 748

Query: 259 TADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPEGSETS 318
            A   PV S  +S +   +  L   +   LK       E+++   +       P  S  +
Sbjct: 749 RARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLVSLPTESTKA 808

Query: 319 VLRGEPLTAGVPRPPSL 335
           V    PL      PPSL
Sbjct: 809 VTTNSPL------PPSL 819


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 45/184 (24%), Positives = 71/184 (38%), Gaps = 14/184 (7%)

Query: 56  IDPSLQAENRIPG---PSQTTAAAPKQQKS-RPTASRDERFRSDVHTEAVQAALAKYKER 111
           ++P+L A  +IP    PS +T        +  P  +     R +V+T +  A LA     
Sbjct: 101 VNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNS- 159

Query: 112 KMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVE-----PW 166
             P P    +     S  T  PP +S+  E   +   P   T  P  S +  E     P 
Sbjct: 160 --PAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPT 217

Query: 167 LDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHID--LHSAP 224
                    +SS+   T++ P     T P+  ++     TTA+    + T +D    SAP
Sbjct: 218 PPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAP 277

Query: 225 PDVT 228
           P+ T
Sbjct: 278 PETT 281



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 36/151 (23%), Positives = 54/151 (35%), Gaps = 14/151 (9%)

Query: 67  PGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMP----MPSKRRSV 122
           P P  TTAA P      P+A+      S    E   A        + P     P +  + 
Sbjct: 160 PAPQDTTAAPPT-----PSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAA 214

Query: 123 LVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHS-----SVEPWLDRVIQGSSTS 177
                  T  PP +S+  E   +   P   T  PL S +     +V P         S++
Sbjct: 215 PPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSA 274

Query: 178 SSASSTSSHPGGRPTTAPSAAATPGAAATTA 208
           S+   T++ P     T P+  ++P    TTA
Sbjct: 275 SAPPETTAAPPTPSATTPAPPSSPAPQETTA 305


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 45/184 (24%), Positives = 71/184 (38%), Gaps = 14/184 (7%)

Query: 56  IDPSLQAENRIPG---PSQTTAAAPKQQKS-RPTASRDERFRSDVHTEAVQAALAKYKER 111
           ++P+L A  +IP    PS +T        +  P  +     R +V+T +  A LA     
Sbjct: 101 VNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNS- 159

Query: 112 KMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVE-----PW 166
             P P    +     S  T  PP +S+  E   +   P   T  P  S +  E     P 
Sbjct: 160 --PAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPT 217

Query: 167 LDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHID--LHSAP 224
                    +SS+   T++ P     T P+  ++     TTA+    + T +D    SAP
Sbjct: 218 PPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAP 277

Query: 225 PDVT 228
           P+ T
Sbjct: 278 PETT 281



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 36/151 (23%), Positives = 54/151 (35%), Gaps = 14/151 (9%)

Query: 67  PGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMP----MPSKRRSV 122
           P P  TTAA P      P+A+      S    E   A        + P     P +  + 
Sbjct: 160 PAPQDTTAAPPT-----PSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAA 214

Query: 123 LVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHS-----SVEPWLDRVIQGSSTS 177
                  T  PP +S+  E   +   P   T  PL S +     +V P         S++
Sbjct: 215 PPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSA 274

Query: 178 SSASSTSSHPGGRPTTAPSAAATPGAAATTA 208
           S+   T++ P     T P+  ++P    TTA
Sbjct: 275 SAPPETTAAPPTPSATTPAPPSSPAPQETTA 305


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 45/184 (24%), Positives = 71/184 (38%), Gaps = 14/184 (7%)

Query: 56  IDPSLQAENRIPG---PSQTTAAAPKQQKS-RPTASRDERFRSDVHTEAVQAALAKYKER 111
           ++P+L A  +IP    PS +T        +  P  +     R +V+T +  A LA     
Sbjct: 101 VNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNS- 159

Query: 112 KMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVE-----PW 166
             P P    +     S  T  PP +S+  E   +   P   T  P  S +  E     P 
Sbjct: 160 --PAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPT 217

Query: 167 LDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHID--LHSAP 224
                    +SS+   T++ P     T P+  ++     TTA+    + T +D    SAP
Sbjct: 218 PPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAP 277

Query: 225 PDVT 228
           P+ T
Sbjct: 278 PETT 281



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 36/151 (23%), Positives = 54/151 (35%), Gaps = 14/151 (9%)

Query: 67  PGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMP----MPSKRRSV 122
           P P  TTAA P      P+A+      S    E   A        + P     P +  + 
Sbjct: 160 PAPQDTTAAPPT-----PSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAA 214

Query: 123 LVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHS-----SVEPWLDRVIQGSSTS 177
                  T  PP +S+  E   +   P   T  PL S +     +V P         S++
Sbjct: 215 PPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSA 274

Query: 178 SSASSTSSHPGGRPTTAPSAAATPGAAATTA 208
           S+   T++ P     T P+  ++P    TTA
Sbjct: 275 SAPPETTAAPPTPSATTPAPPSSPAPQETTA 305


>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
          Length = 354

 Score = 39.7 bits (91), Expect = 0.011
 Identities = 44/163 (26%), Positives = 75/163 (46%), Gaps = 26/163 (15%)

Query: 69  PSQTTAAAP-KQQKSRPTASRDERFRSDVHTEAVQAALAK--YKERKMPMPSKRRSVLVH 125
           PS    A P KQ++ R T +R +        + ++A  AK  Y +  M      +  L  
Sbjct: 27  PSVGYPATPRKQRRERTTFTRSQ-------LDVLEALFAKTRYPDIFMREEVALKINLPE 79

Query: 126 SSVETYTPPDTSSASEDE----GSLRRPGRLTSTPLQ----SHSSVEPWLDRVIQGSSTS 177
           S V+ +     +   + +    G+  RP +  S+P++    S SS +     V   +S+S
Sbjct: 80  SRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSS 139

Query: 178 SSASSTSSHP--------GGRPTTAPSAAATPGAAATTALAGL 212
           SSASS+S++P        GG P  A S+ +TP A++  + A +
Sbjct: 140 SSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPASI 182


>gi|111120318 NK6 transcription factor related, locus 1 [Homo
           sapiens]
          Length = 367

 Score = 37.7 bits (86), Expect = 0.043
 Identities = 40/122 (32%), Positives = 56/122 (45%), Gaps = 20/122 (16%)

Query: 132 TPPDTSSASEDEGS---LRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPG 188
           +PP   SA+   G    L RP    S P+ S ++        +  +S S S+SS+SS   
Sbjct: 85  SPPQQLSAATPHGINDILSRP----SMPVASGAA--------LPSASPSGSSSSSSSSAS 132

Query: 189 GRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSV 248
               +A +AAA   AAA ++ AGL A        +PP    GL    YF  P  A+V +V
Sbjct: 133 ASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGL----YFS-PSAAAVAAV 187

Query: 249 PR 250
            R
Sbjct: 188 GR 189


>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 3 [Homo sapiens]
          Length = 1212

 Score = 37.7 bits (86), Expect = 0.043
 Identities = 37/140 (26%), Positives = 64/140 (45%), Gaps = 11/140 (7%)

Query: 57  DPSLQAENRIPGPSQTTAAAPKQQKSR----PTASRDERFRSDVHTEAVQAALAKYKERK 112
           D + + E+R    + ++  A  +Q  R    P  SR E F S+ ++E+V  AL +  E +
Sbjct: 533 DRAREVEDRFRKTNHSSPEAQSKQTGRVLEPPVPSRSESF-SNGNSESVHPALQRPAEPQ 591

Query: 113 MPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQ 172
           +P+ +  RS ++         P   S  ++  + +R    +  P      VE  + R   
Sbjct: 592 VPVRTTSRSPVLSRR----DSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGS 647

Query: 173 GSST--SSSASSTSSHPGGR 190
           GSS+  S+S S   SHPG +
Sbjct: 648 GSSSGSSNSGSQPGSHPGSQ 667


>gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 [Homo
            sapiens]
          Length = 2542

 Score = 37.7 bits (86), Expect = 0.043
 Identities = 33/134 (24%), Positives = 58/134 (43%), Gaps = 22/134 (16%)

Query: 84   PTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVET-YTPPDTSSASED 142
            P++ R + F     T      ++        +PS   + +      T + P  TS A   
Sbjct: 1955 PSSVRKQLFACVPKTSPPATVISSVTSTCSSLPSVSSAPITSGQAPTTFLPASTSQA--- 2011

Query: 143  EGSLRRPGRLTSTPLQSHSSVEPWLDRV----------IQGSSTSSSASSTSSHPGGRPT 192
                    +L+S  ++S S+V P  ++V             SST++S SS++S+  G P 
Sbjct: 2012 --------QLSSQKMESFSAVPPTKEKVSTQDQPMANLCTPSSTANSCSSSASNTPGAPE 2063

Query: 193  TAPSAAATPGAAAT 206
            T PS++ TP ++ T
Sbjct: 2064 THPSSSPTPTSSNT 2077


>gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens]
          Length = 2617

 Score = 37.7 bits (86), Expect = 0.043
 Identities = 33/134 (24%), Positives = 58/134 (43%), Gaps = 22/134 (16%)

Query: 84   PTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVET-YTPPDTSSASED 142
            P++ R + F     T      ++        +PS   + +      T + P  TS A   
Sbjct: 1955 PSSVRKQLFACVPKTSPPATVISSVTSTCSSLPSVSSAPITSGQAPTTFLPASTSQA--- 2011

Query: 143  EGSLRRPGRLTSTPLQSHSSVEPWLDRV----------IQGSSTSSSASSTSSHPGGRPT 192
                    +L+S  ++S S+V P  ++V             SST++S SS++S+  G P 
Sbjct: 2012 --------QLSSQKMESFSAVPPTKEKVSTQDQPMANLCTPSSTANSCSSSASNTPGAPE 2063

Query: 193  TAPSAAATPGAAAT 206
            T PS++ TP ++ T
Sbjct: 2064 THPSSSPTPTSSNT 2077


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 37.4 bits (85), Expect = 0.056
 Identities = 62/236 (26%), Positives = 88/236 (37%), Gaps = 49/236 (20%)

Query: 130 TYTPPDTS-SASEDEGSL-RRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHP 187
           T TPP  S + +    SL R+P R + T + S +S+   +D     + T   AS T + P
Sbjct: 386 TGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSITK-MDSTASPTRTPPRASPTGTPP 444

Query: 188 GGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRS 247
              PT  PS A+  G  +T +  G  +       +A P   TG         P  AS   
Sbjct: 445 RASPTGTPSRASPTGTQSTASPTGSPS-------TASP---TG--------SPSTASPTG 486

Query: 248 VPRGCSGSMLETADGVPVNSRVS-SKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPD 306
            P     S+  T       SR S +K++   +  + P R                     
Sbjct: 487 SP--SRASLTRTP------SRASLTKMESTASITRTPSRAS---------------PTWT 523

Query: 307 PNQPKPEGS-ETSVLRGEPLTAGVPRPP---SLLATLQRWGTTQPKSPCLTALDTT 358
           P+   P GS  T++  G P  A + R P   SL  T  R   T P    LT   +T
Sbjct: 524 PSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRTPST 579



 Score = 31.2 bits (69), Expect = 4.0
 Identities = 53/202 (26%), Positives = 74/202 (36%), Gaps = 43/202 (21%)

Query: 176 TSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHS 235
           T S AS T       PT  PS A+  G+ +T +L GL + T     + P    TG     
Sbjct: 343 TPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSS-TASPTGTPPRASPTG----- 396

Query: 236 YFERPQVASV-RSVPRGCSGSMLETADGVPVNSRVS-SKIQQLLNTLKRPKR------PP 287
               P  AS+ R  PR     ML         SR S +K+    +  + P R      PP
Sbjct: 397 ---TPSTASLTRKPPRASPTGML---------SRTSITKMDSTASPTRTPPRASPTGTPP 444

Query: 288 LKEFFVDDFEELLEVQQPDPNQPKPEGSE-TSVLRGEPLTA---GVPRPPSLLATLQRWG 343
                              P++  P G++ T+   G P TA   G P   S   +  R  
Sbjct: 445 RAS------------PTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRAS 492

Query: 344 TTQ-PKSPCLTALDTTGKAVYT 364
            T+ P    LT +++T     T
Sbjct: 493 LTRTPSRASLTKMESTASITRT 514



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 36/167 (21%), Positives = 64/167 (38%), Gaps = 18/167 (10%)

Query: 127 SVETYTPPDTSSASEDEGS------LRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSA 180
           S  T +P  + S +   GS       R P R + T ++S +S+          + T S A
Sbjct: 469 SPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTASI----------TRTPSRA 518

Query: 181 SSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERP 240
           S T +     PT +PS A   G+ +  AL    +   +    +   +TT     S    P
Sbjct: 519 SPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTP-SRASLTRTP 577

Query: 241 QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPP 287
               +  +P   S + + +    P     S+ + ++ +T    + PP
Sbjct: 578 STVLLTRMPPSASPTGMPSRTS-PTGMPSSALLTKMDSTASITRTPP 623


>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
           sapiens]
          Length = 1077

 Score = 37.4 bits (85), Expect = 0.056
 Identities = 65/308 (21%), Positives = 117/308 (37%), Gaps = 42/308 (13%)

Query: 61  QAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEA-VQAALAKYKERKMPMPSKR 119
           QA+ +    +Q  A A  Q +++  A    + ++ V  +   QA  A       P P+  
Sbjct: 212 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPA-- 269

Query: 120 RSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSS 179
               V +S  + TP  T+S +    S+ +     +T  Q+ SS        +  S+ + +
Sbjct: 270 ----VSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPT 325

Query: 180 ASSTSSHPGGRPTTAPSAAATPGAAATTALAG----LEAHTHIDLHSAP---PDVTTGLV 232
           A+   + P   P T P A        TTA+      +     + L   P   P V  G+ 
Sbjct: 326 ATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMA 385

Query: 233 EHSY-FERPQVASVRSVPRGCSGSM-------LETADG---------------VPVNSRV 269
                   PQVA + + P   +G+         +TADG                P   + 
Sbjct: 386 PPIVPMIHPQVA-IAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKE 444

Query: 270 SSKIQQ-LLNTLKRPKRPPL--KEFFVDDFEELLEVQQPDPNQPKPEGSETSVLRGEPL- 325
             K+++ +   +K P   PL  +    D  EE ++  + +P + +    E +  + +P+ 
Sbjct: 445 KEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVA 504

Query: 326 TAGVPRPP 333
           TA +P  P
Sbjct: 505 TAPIPGTP 512


>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score = 37.0 bits (84), Expect = 0.073
 Identities = 76/366 (20%), Positives = 139/366 (37%), Gaps = 59/366 (16%)

Query: 51   PLIQGIDPSLQAENR---IPGPSQTTAAAPKQ-QKSRPTASRDERFRSDVHTEAVQAALA 106
            PL   ++P + A       PGP+QTT   P +   S+  A   E   S   T ++ A   
Sbjct: 1443 PLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1502

Query: 107  KYKERKMPMPSKRRSV-LVHSSVETYT-------PPDTSSASEDEGSLRRPGRLTSTPLQ 158
              +   +P+  +  +  +V  ++ET          P+ + +S    + R P    +  ++
Sbjct: 1503 TPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVR 1562

Query: 159  SHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHI 218
             H S+ P     +Q S T+S +S   + PG   + +P+++ +  A  T A+  + + T +
Sbjct: 1563 GHGSL-PVRTTPLQPSLTASPSSRPVASPGAI-SRSPTSSGSHKAVLTPAVTKVISRTGV 1620

Query: 219  DLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLN 278
                  P  T          + Q AS  S P   +G+    A+ VPV+   +  ++ +L+
Sbjct: 1621 ------PQPT----------QAQSASSPSTPLTVAGT---AAEQVPVSPLATRSLEIVLS 1661

Query: 279  TLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLAT 338
            T                       ++ +    +P GS  S  +  PL +  PRP      
Sbjct: 1662 T-----------------------EKGEAGHSQPMGSPASP-QPHPLPSAPPRPAQHTTM 1697

Query: 339  LQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDR 398
              R     P++P   +L T    +    +  L   S + +  L       + PL K G  
Sbjct: 1698 ATRSPALPPETPAAASLSTATDGLAATPFMSL--ESTRPSQLLSGLPPDTSLPLAKVGTS 1755

Query: 399  VALVFP 404
              +  P
Sbjct: 1756 APVATP 1761


>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score = 37.0 bits (84), Expect = 0.073
 Identities = 76/366 (20%), Positives = 139/366 (37%), Gaps = 59/366 (16%)

Query: 51   PLIQGIDPSLQAENR---IPGPSQTTAAAPKQ-QKSRPTASRDERFRSDVHTEAVQAALA 106
            PL   ++P + A       PGP+QTT   P +   S+  A   E   S   T ++ A   
Sbjct: 1515 PLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1574

Query: 107  KYKERKMPMPSKRRSV-LVHSSVETYT-------PPDTSSASEDEGSLRRPGRLTSTPLQ 158
              +   +P+  +  +  +V  ++ET          P+ + +S    + R P    +  ++
Sbjct: 1575 TPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVR 1634

Query: 159  SHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHI 218
             H S+ P     +Q S T+S +S   + PG   + +P+++ +  A  T A+  + + T +
Sbjct: 1635 GHGSL-PVRTTPLQPSLTASPSSRPVASPGAI-SRSPTSSGSHKAVLTPAVTKVISRTGV 1692

Query: 219  DLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLN 278
                  P  T          + Q AS  S P   +G+    A+ VPV+   +  ++ +L+
Sbjct: 1693 ------PQPT----------QAQSASSPSTPLTVAGT---AAEQVPVSPLATRSLEIVLS 1733

Query: 279  TLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLAT 338
            T                       ++ +    +P GS  S  +  PL +  PRP      
Sbjct: 1734 T-----------------------EKGEAGHSQPMGSPASP-QPHPLPSAPPRPAQHTTM 1769

Query: 339  LQRWGTTQPKSPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLKPGDR 398
              R     P++P   +L T    +    +  L   S + +  L       + PL K G  
Sbjct: 1770 ATRSPALPPETPAAASLSTATDGLAATPFMSL--ESTRPSQLLSGLPPDTSLPLAKVGTS 1827

Query: 399  VALVFP 404
              +  P
Sbjct: 1828 APVATP 1833


>gi|66529407 tensin [Homo sapiens]
          Length = 1735

 Score = 37.0 bits (84), Expect = 0.073
 Identities = 52/228 (22%), Positives = 80/228 (35%), Gaps = 18/228 (7%)

Query: 46   LARYIPLIQGIDPSLQAENRIPGPSQTTAAAPKQQKSRPTASRDERFRS--DVHTEAVQA 103
            L  ++P         Q    +PG +     +PK+  S P+ + +E   +   +    V  
Sbjct: 819  LPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAG 878

Query: 104  ALAKYKERKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSV 163
              A+ K+   P    RR        E  +P  TS  S     +R P +  S  L    ++
Sbjct: 879  VQAREKQPAEPPAPLRRRAASDGQYENQSPEATSPRSP---GVRSPVQCVSPELALTIAL 935

Query: 164  -------EPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHT 216
                   EP L    +        S +S  P G   + P  A TP +A      GL+ H 
Sbjct: 936  NPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSG-VRSPPGLAKTPLSAL-----GLKPHN 989

Query: 217  HIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCSGSMLETADGVP 264
              D+   P  VT   ++    E   V  +   PR    S+  TA   P
Sbjct: 990  PADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAVAGP 1037


>gi|20270323 zinc finger protein 653 [Homo sapiens]
          Length = 615

 Score = 37.0 bits (84), Expect = 0.073
 Identities = 58/235 (24%), Positives = 88/235 (37%), Gaps = 50/235 (21%)

Query: 155 TPLQSHSSVEPWLDRVIQG-------SSTSSSASSTSSHPGGRPTTAPSAAATPGAAATT 207
           +PL+  S  +P  D+V  G       SS+S SAS +   P G+P  A +AAA     +  
Sbjct: 172 SPLKPLSDSDPDSDKVGNGLVAGSSDSSSSGSASDSEESPEGQPVKAAAAAAAATPTSPV 231

Query: 208 ALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCSGSMLETADGVPVNS 267
             +GL     + +   P D     V H      Q   + S P G     LET   VPV  
Sbjct: 232 GSSGLITQEGVHI---PFD-----VHHVESLAEQGTPLCSNPAGNGPEALETVVCVPVPV 283

Query: 268 RVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPEGSETSVLRG---EP 324
           +V +    L   + +              E L EV    P      GS+  ++ G   + 
Sbjct: 284 QVGAGPSALFENVPQ--------------EALGEVVASCPMPGMVPGSQVIIIAGPGYDA 329

Query: 325 LTA-----------GVPR-------PPSLLATLQRWGTTQPKSPCLTALDTTGKA 361
           LTA           GVP        P +++  +  +  T+P+    + +D T  A
Sbjct: 330 LTAEGIHLNMAAGSGVPGSGLGEEVPCAMMEGVAAYTQTEPEGSQPSTMDATAVA 384


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 36.6 bits (83), Expect = 0.096
 Identities = 64/261 (24%), Positives = 91/261 (34%), Gaps = 24/261 (9%)

Query: 111  RKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRV 170
            +K+ +PS  R   V S+     P  TS AS   G++   G  +S  L   +S+ P     
Sbjct: 994  QKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVAL-GFTSLGPSGPAF 1052

Query: 171  IQ-----GSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPP 225
            +Q     G +   +       P   P   P+ AA  G   T   +G  A T     + P 
Sbjct: 1053 VQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPS 1112

Query: 226  DVTTGLVEH-SYFERPQVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPK 284
                 LV   +    P  A++  +P+G       TA   P +   S+    +  +L  PK
Sbjct: 1113 QAPPSLVYTVATSTTPPAATI--LPKGPPAPA--TATPAPTSPFPSATAGSMTYSLVAPK 1168

Query: 285  --RPPLK----------EFFVDDFEELLEVQQ-PDPNQPKPEGSETSVLRGEPLTAGVPR 331
              RP  K             V  FE     +  P P QP   G        E    G P 
Sbjct: 1169 AQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPT 1228

Query: 332  PPSLLATLQRWGTTQPKSPCL 352
            PP+     + W  T   SP L
Sbjct: 1229 PPAPPPLPETWTPTARSSPPL 1249


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 36.2 bits (82), Expect = 0.13
 Identities = 61/266 (22%), Positives = 97/266 (36%), Gaps = 41/266 (15%)

Query: 25    ELELSEGDITQKGYEKKRAKLLARYIPLIQGIDPSLQAENRIPGPSQTTAAAPKQQKSRP 84
             ELE +    T  G E   A       P + G+   L   +R    + T+   P    S  
Sbjct: 11066 ELETTPSMATSHGAEASSAVPTPTVSPGVSGVVTPLVTSSR----AVTSTTIPILTLSSS 11121

Query: 85    TASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEG 144
                      +    EA  A L    E    +P    S++  S   T T   T + S DE 
Sbjct: 11122 EPETTPSMATSHGVEASSAVLTVSPE----VPGMVTSLVTSSRAVTSTTIPTLTISSDEP 11177

Query: 145   SLRRPGRLTSTPLQSHS---------------SVEPWLDRVIQGSSTSSSASSTSSHPGG 189
                     T+T L +HS               +V+  +  ++  S + +SA S  +    
Sbjct: 11178 E-------TTTSLVTHSEAKMISAIPTLAVSPTVQGLVTSLVTSSGSETSAFSNLTVASS 11230

Query: 190   RPTTAPSAAATPGAAATTALAGL-----EAHTHIDLHSAPPDVTTGL----VEHSYFERP 240
             +P T  S  A PG  A++ +  L     E  T+I L + P + ++ L       S+ E  
Sbjct: 11231 QPETIDSWVAHPGTEASSVVPTLTVSTGEPFTNISLVTHPAESSSTLPRTTSRFSHSELD 11290

Query: 241   QVASVRSVPRGCSGSMLET--ADGVP 264
              + S  + P   S S + T  + G+P
Sbjct: 11291 TMPSTVTSPEAESSSAISTTISPGIP 11316



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 70/316 (22%), Positives = 114/316 (36%), Gaps = 46/316 (14%)

Query: 116   PSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVE-----PWLDRV 170
             P    + L H +  + T   T       GS   P  +TS  + + S V      P +  V
Sbjct: 11571 PETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTTTIPPSIPGV 11630

Query: 171   IQGSSTSSSASSTSSHPG-----GRPTTAPSAAATPGAAA--TTALAGLEAH-------- 215
             +    TSS+  ++++ P      G P T  S+A  PG     T  +  + +         
Sbjct: 11631 VTSQVTSSATDTSTAIPTLTPSPGEPETTASSATHPGTQTGFTVPIRTVPSSEPDTMASW 11690

Query: 216   -THIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRGCSGSMLETADGVP--VNSRVSSK 272
              TH    S P   TT    HS  +   V +        S  +   + G P  V S+++S 
Sbjct: 11691 VTHPPQTSTPVSRTTSSFSHSSPDATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSS 11750

Query: 273   IQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRP 332
                   T+      P           + E        P+ E S+T      P +   P+ 
Sbjct: 11751 GAATSTTVPTLTHSP----------GMPETTALLSTHPRTETSKTF-----PASTVFPQV 11795

Query: 333   PSLLATLQRWGTTQPKSPCLTALDT-TGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKNEP 391
                 A+L    T +P +   TAL T T  +++TL      +  + L+ T    +++K  P
Sbjct: 11796 SETTASL----TIRPGAETSTALPTQTTSSLFTLLV--TGTSRVDLSPTASPGVSAKTAP 11849

Query: 392   L-LKPGDRVALVFPNS 406
             L   PG   + + P S
Sbjct: 11850 LSTHPGTETSTMIPTS 11865



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 49/229 (21%), Positives = 85/229 (37%), Gaps = 10/229 (4%)

Query: 66   IPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVH 125
            IP  S+TT    +   S     R+     ++ T + + +   YKE         R+ +  
Sbjct: 4876 IPKSSKTTRTETETTSSLTPKLRETSISQEI-TSSTETSTVPYKELTGATTEVSRTDVTS 4934

Query: 126  SSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSS 185
            SS  ++  PD S+ S D  S     RL+++P+ + S+ E  +         +S  + T  
Sbjct: 4935 SSSTSFPGPDQSTVSLDI-STETNTRLSTSPIMTESA-EITITTQTGPHGATSQDTFTMD 4992

Query: 186  HPGGRPTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASV 245
                 P     +A T G +       +         ++PP V       S+   P +   
Sbjct: 4993 PSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAM--- 5049

Query: 246  RSVPRGCSGSMLETADGVPVNSRVSS---KIQQLLNTLKRPKRPPLKEF 291
             + P   S ++ E     P+ S ++S   KI  +L T   P    L  F
Sbjct: 5050 -TTPSLISSTLPEDKLSSPMTSLLTSGLVKITDILRTRLEPVTSSLPNF 5097



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 43/166 (25%), Positives = 66/166 (39%), Gaps = 17/166 (10%)

Query: 55   GIDPSLQAENRIPGPSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAA---LAKYKER 111
            G  PS+    R       T+AAP       TAS  E     +  E        L   K  
Sbjct: 2306 GASPSITLGER----RTITSAAPTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTN 2361

Query: 112  KMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVI 171
            ++P  S   S L+++S+ + T   T +AS    S+   G   S+     SS  P +    
Sbjct: 2362 ELPSDSSSSSDLINTSIASSTMDVTKTASISPTSIS--GMTASSSPSLFSSDRPQVPTST 2419

Query: 172  QGSSTSSSASSTS--------SHPGGRPTTAPSAAATPGAAATTAL 209
              ++T++S S +S        S+ GG P+T P    T     ++AL
Sbjct: 2420 TETNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFTITHPVETSSAL 2465



 Score = 33.9 bits (76), Expect = 0.62
 Identities = 55/225 (24%), Positives = 85/225 (37%), Gaps = 36/225 (16%)

Query: 131 YTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGR 190
           ++ P+  SA   + S       TS PL S +SV   L+  +  +ST S   +TSS   G 
Sbjct: 707 FSSPEPDSAGHTKIS-------TSIPLLSSASV---LEDKVSATSTFSHHKATSSITTGT 756

Query: 191 PTTAPSAAATPGAAATTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPR 250
           P    S    P +A  +++    A T  +      + T+ L   S        SV ++  
Sbjct: 757 PEI--STKTKPSSAVLSSMTLSNAATSPE---RVRNATSPLTHPSPSGEETAGSVLTL-- 809

Query: 251 GCSGSMLETADGVPVN--SRVSSKIQQLLNTLKRPKRPPLKEFFVDDF---------EEL 299
               +  ET D   ++    ++S+  +  +TL  P    +K  F             EE 
Sbjct: 810 ---STSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEET 866

Query: 300 LEVQQPDPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGT 344
            E   P  +QP     ETSV R     A    P  +  T+  W T
Sbjct: 867 EETSNPSVSQP-----ETSVSRVRTTLASTSVPTPVFPTMDTWPT 906



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 32/132 (24%), Positives = 47/132 (35%), Gaps = 27/132 (20%)

Query: 125   HSSVETYTPPDTSSASEDEGSLRR------PGRLTSTPLQSHSSVEPWLDRVIQGSSTSS 178
             HS ++T     TS  +E   ++        PG LTS    S   +      V +    S 
Sbjct: 11286 HSELDTMPSTVTSPEAESSSAISTTISPGIPGVLTSLVTSSGRDISATFPTVPESPHESE 11345

Query: 179   SASSTSSHPGGR---------------PTTAPSAAATPGAAATTALAGLEAHTHIDLHSA 223
             + +S  +HP                  P T PS A +PGA AT+    +     +     
Sbjct: 11346 ATASWVTHPAVTSTTVPRTTPNYSHSEPDTTPSIATSPGAEATSDFPTITVSPDV----- 11400

Query: 224   PPDVTTGLVEHS 235
              PD+ T  V  S
Sbjct: 11401 -PDMVTSQVTSS 11411



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 53/241 (21%), Positives = 86/241 (35%), Gaps = 34/241 (14%)

Query: 153   TSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPGGRPTT---------------APSA 197
             TS+   +++   P    ++Q S T  ++S+ +S P   P +               +PS 
Sbjct: 10178 TSSVTPTNTPSSPGSTHLLQSSKTDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSI 10237

Query: 198   AATPGAAA------TTALAGLEAHTHIDLHSAPPDVTTGLVEHSYFERPQVASVRSVPRG 251
               + G  +      T ++     H   DL  +   ++TG V  S  E     +   VPR 
Sbjct: 10238 TESTGITSFPESRFTMSVTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRA 10297

Query: 252   CSGSMLETADGVPVNSRVSSKIQQLLNTLKR--PKRPPL----KEFFVDDFEELLEVQQP 305
              SGS      G P +   S      L+T+    P   P+      F   D   +  + + 
Sbjct: 10298 ISGS------GSPFSRTESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEI 10351

Query: 306   DPNQPKPEGSETSVLRGEPLTAGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAVYTL 365
               +   P   +TS+      T G     S L T  + G T   SP L    T    + T+
Sbjct: 10352 TSSSATPYRVDTSLGTESSTTEGRLVMVSTLDTSSQPGRTS-SSPILDTRMTESVELGTV 10410

Query: 366   T 366
             T
Sbjct: 10411 T 10411



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 28/115 (24%), Positives = 44/115 (38%), Gaps = 17/115 (14%)

Query: 100   AVQAALAKYKERKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQS 159
             A   +L  +  +  P      S+  HS  +T     TS  +E   ++  P   T  P   
Sbjct: 10819 ATTVSLVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHGAESSSAVPTPTVSTEVP--- 10875

Query: 160   HSSVEPWLDRVIQGSSTSSSASSTSSHP-----GGRPTTAPSAAATPGAAATTAL 209
                       V+    TSS A  +++ P      G P T PS A + G  A++A+
Sbjct: 10876 ---------GVVTPLVTSSRAVISTTIPILTLSPGEPETTPSMATSHGEEASSAI 10921



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 38/146 (26%), Positives = 59/146 (40%), Gaps = 24/146 (16%)

Query: 69    PSQTTAAAPKQQKSRPTASRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSV 128
             PS TT+   +   + PT +        V TE V   +         + S    +L  S  
Sbjct: 10851 PSMTTSHGAESSSAVPTPT--------VSTE-VPGVVTPLVTSSRAVISTTIPILTLSPG 10901

Query: 129   ETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRVIQGSSTSSSASSTSSHPG 188
             E  T P  +++  +E S   P     TP     +V P +  V+    TSS A ++++ P 
Sbjct: 10902 EPETTPSMATSHGEEASSAIP-----TP-----TVSPGVPGVVTSLVTSSRAVTSTTIPI 10951

Query: 189   -----GRPTTAPSAAATPGAAATTAL 209
                  G P T PS A + G  A +A+
Sbjct: 10952 LTFSLGEPETTPSMATSHGTEAGSAV 10977


>gi|57546899 myeloid/lymphoid or mixed-lineage leukemia translocated
           to, 10 isoform b [Homo sapiens]
          Length = 1011

 Score = 35.8 bits (81), Expect = 0.16
 Identities = 49/197 (24%), Positives = 81/197 (41%), Gaps = 28/197 (14%)

Query: 107 KYKERKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRR----PGRLTSTPLQSHSS 162
           K+K++  P P+   S+ V ++ +TYT    +S S   GSL+R      R T+   Q  S+
Sbjct: 244 KHKKQPEPSPALVPSLTV-TTEKTYTSTSNNSIS---GSLKRLEDTTARFTNANFQEVSA 299

Query: 163 VEPWLDRVIQGSSTSSSASSTSSHPGGRPTTAPSAAATPG---AAATTALAGLEAHTHID 219
                  V +   +      +S+H  G+    P     PG   +AA+    G  + T   
Sbjct: 300 HTSSGKDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGS 359

Query: 220 LHS-------APPD----VTTGLVEHSYFERPQVASVRSVPRGCSGSM------LETADG 262
           + S       +P D      + L   SY    Q ++ + V +G SGS         T  G
Sbjct: 360 VKSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIG 419

Query: 263 VPVNSRVSSKIQQLLNT 279
           +P  S V+S+ +   N+
Sbjct: 420 LPSTSAVTSQPKSFENS 436


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,952,787
Number of Sequences: 37866
Number of extensions: 1681485
Number of successful extensions: 8501
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 253
Number of HSP's that attempted gapping in prelim test: 7752
Number of HSP's gapped (non-prelim): 880
length of query: 812
length of database: 18,247,518
effective HSP length: 111
effective length of query: 701
effective length of database: 14,044,392
effective search space: 9845118792
effective search space used: 9845118792
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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