Guide to the Human Genome
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Search of human proteins with 4557791

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557791 neuraminidase precursor [Homo sapiens]
         (415 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557791 neuraminidase precursor [Homo sapiens]                     858   0.0  
gi|117190519 sialidase 3 [Homo sapiens]                                67   3e-11
gi|21704287 sialidase 4 [Homo sapiens]                                 67   4e-11
gi|222352170 neuraminidase 2 [Homo sapiens]                            63   6e-10
gi|11321571 slit homolog 3 [Homo sapiens]                              30   4.0  
gi|91823271 xanthine dehydrogenase [Homo sapiens]                      29   6.9  
gi|157738645 plexin A4 isoform 1 [Homo sapiens]                        29   9.0  

>gi|4557791 neuraminidase precursor [Homo sapiens]
          Length = 415

 Score =  858 bits (2217), Expect = 0.0
 Identities = 415/415 (100%), Positives = 415/415 (100%)

Query: 1   MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAENDFGLVQPLVTM 60
           MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAENDFGLVQPLVTM
Sbjct: 1   MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAENDFGLVQPLVTM 60

Query: 61  EQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSSDEGAKFIALRRSMDQGST 120
           EQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSSDEGAKFIALRRSMDQGST
Sbjct: 61  EQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSSDEGAKFIALRRSMDQGST 120

Query: 121 WSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQVASTMLVWSKDDGVS 180
           WSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQVASTMLVWSKDDGVS
Sbjct: 121 WSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQVASTMLVWSKDDGVS 180

Query: 181 WSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGASW 240
           WSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGASW
Sbjct: 181 WSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGASW 240

Query: 241 RYGSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIVLRSYDACD 300
           RYGSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIVLRSYDACD
Sbjct: 241 RYGSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIVLRSYDACD 300

Query: 301 TLRPRDVTFDPELVDPVVAAGAVVTSSGIVFFSNPAHPEFRVNLTLRWSFSNGTSWRKET 360
           TLRPRDVTFDPELVDPVVAAGAVVTSSGIVFFSNPAHPEFRVNLTLRWSFSNGTSWRKET
Sbjct: 301 TLRPRDVTFDPELVDPVVAAGAVVTSSGIVFFSNPAHPEFRVNLTLRWSFSNGTSWRKET 360

Query: 361 VQLWPGPSGYSSLATLEGSMDGEEQAPQLYVLYEKGRNHYTESISVAKISVYGTL 415
           VQLWPGPSGYSSLATLEGSMDGEEQAPQLYVLYEKGRNHYTESISVAKISVYGTL
Sbjct: 361 VQLWPGPSGYSSLATLEGSMDGEEQAPQLYVLYEKGRNHYTESISVAKISVYGTL 415


>gi|117190519 sialidase 3 [Homo sapiens]
          Length = 461

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 63/200 (31%), Positives = 93/200 (46%), Gaps = 39/200 (19%)

Query: 76  TFRIP-LITATPRGTLLAFAEARKMSSSDEGAKFIALRRSMDQGST--WSPTAFIVNDGD 132
           T+RIP L+   P  T LAFAE R  +  DE A  + LRR +  G    W P   ++ +  
Sbjct: 56  TYRIPALLYIPPTHTFLAFAEKRS-TRRDEDALHLVLRRGLRIGQLVQWGPLKPLM-EAT 113

Query: 133 VPDGLNLGAV-VSDVETGVVFLFYSLCAHK---------AGCQVASTMLVWSKDDGVSWS 182
           +P    +    V + ++G VFLF+ +C            +G   A    ++S+D G SWS
Sbjct: 114 LPGHRTMNPCPVWEQKSGCVFLFF-ICVRGHVTERQQIVSGRNAARLCFIYSQDAGCSWS 172

Query: 183 TPRNLSLD-IGTEV-----FAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFC------ 230
             R+L+ + IG+E+     FA GPG GIQ Q     GRL++  +        FC      
Sbjct: 173 EVRDLTEEVIGSELKHWATFAVGPGHGIQLQ----SGRLVIPAYTYYIPSWFFCFQLPCK 228

Query: 231 -------LLSDDHGASWRYG 243
                  + SDD G +W +G
Sbjct: 229 TRPHSLMIYSDDLGVTWHHG 248


>gi|21704287 sialidase 4 [Homo sapiens]
          Length = 496

 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 66/207 (31%), Positives = 95/207 (45%), Gaps = 34/207 (16%)

Query: 76  TFRIPLITATPRG-TLLAFAEARKMSSSDEGAKFIALRR-SMDQGSTWSPTAFIVNDGDV 133
           T+R+P +   P G TLLAF E R +S  D  A  + LRR ++  GS       ++    +
Sbjct: 33  TYRVPSLLPVPPGPTLLAFVEQR-LSPDDSHAHRLVLRRGTLAGGSVRWGALHVLGTAAL 91

Query: 134 PDGLNLGAV-VSDVETGVVFLFY-SLCAHK-------AGCQVASTMLVWSKDDGVSWSTP 184
            +  ++    V D  TG VFLF+ ++  H         G   A    V S+D G+SW + 
Sbjct: 92  AEHRSMNPCPVHDAGTGTVFLFFIAVLGHTPEAVQIATGRNAARLCCVASRDAGLSWGSA 151

Query: 185 RNLSLD-IGTEV-----FAPGPGSGIQKQREPRKGRLIVCGH----------GTLERDGV 228
           R+L+ + IG  V     FA GPG G+Q       GRL+V  +          G + R   
Sbjct: 152 RDLTEEAIGGAVQDWATFAVGPGHGVQLP----SGRLLVPAYTYRVDRRECFGKICRTSP 207

Query: 229 --FCLLSDDHGASWRYGSGVSGIPYGQ 253
             F   SDDHG +WR G  V  +  G+
Sbjct: 208 HSFAFYSDDHGRTWRCGGLVPNLRSGE 234



 Score = 32.7 bits (73), Expect = 0.62
 Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 6/84 (7%)

Query: 330 VFFSNPAHPEFRVNLTLRWSFS--NGTSWRKETVQLWPGPSGYSSLATLEGSMDGEEQAP 387
           + +S+P     R+++ +R S S  +  SW +  V ++ GPSGYS LA++  + +G     
Sbjct: 390 LLYSHPVGRRARLHMGIRLSQSPLDPRSWTEPWV-IYEGPSGYSDLASIGPAPEG---GL 445

Query: 388 QLYVLYEKGRNHYTESISVAKISV 411
               LYE G     + IS    S+
Sbjct: 446 VFACLYESGARTSYDEISFCTFSL 469


>gi|222352170 neuraminidase 2 [Homo sapiens]
          Length = 380

 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 102/372 (27%), Positives = 150/372 (40%), Gaps = 72/372 (19%)

Query: 77  FRIPLITATP-RGTLLAFAEARKMSSSDEGAKFIALRRSMDQGST----WSPTAFIVNDG 131
           +RIP +   P + +LLAFAE R  S  DE A+ I LRR      T    W     +    
Sbjct: 20  YRIPALLYLPGQQSLLAFAEQRA-SKKDEHAELIVLRRGDYDAPTHQVQWQAQEVVAQAR 78

Query: 132 -DVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQ--------VASTMLVWSKDDGVSWS 182
            D    +N    + D +TG +FLF+     +   Q        V     V S D G +WS
Sbjct: 79  LDGHRSMN-PCPLYDAQTGTLFLFFIAIPGQVTEQQQLQTRANVTRLCQVTSTDHGRTWS 137

Query: 183 TPRNLS-LDIGT-----EVFAPGPGSGIQKQREPRKGRLIVCGHG-----TLERD--GVF 229
           +PR+L+   IG        FA GPG  +Q     R   L+V  +       ++R     F
Sbjct: 138 SPRDLTDAAIGPAYREWSTFAVGPGHCLQLHDRARS--LVVPAYAYRKLHPIQRPIPSAF 195

Query: 230 CLLSDDHGASWRYGSGVSGIPYGQPKQENDFNPDECQPYELPDGS---VVINARNQNNYH 286
           C LS DHG +W  G  V+             +  ECQ  E+  G    V +NAR+     
Sbjct: 196 CFLSHDHGRTWARGHFVAQ------------DTLECQVAEVETGEQRVVTLNARS----- 238

Query: 287 CHCRIVLRSYDACDTLRPRDVTFDPELVDPVV--AAGAVV----------TSSGIVFFSN 334
            H R  +++    D L  ++     +LV+P      G+V+          + +  + +++
Sbjct: 239 -HLRARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSGPGSPAQWLLYTH 297

Query: 335 PAHPEFRVNL--TLRWSFSNGTSWRKETVQLWPGPSGYSSLATLEGSMDGEEQAPQLYVL 392
           P H   R +L   L        +W  E V L  G   YS L ++    DG   +P    L
Sbjct: 298 PTHSWQRADLGAYLNPRPPAPEAW-SEPVLLAKGSCAYSDLQSMGTGPDG---SPLFGCL 353

Query: 393 YEKGRNHYTESI 404
           YE   N Y E +
Sbjct: 354 YE--ANDYEEIV 363


>gi|11321571 slit homolog 3 [Homo sapiens]
          Length = 1523

 Score = 30.0 bits (66), Expect = 4.0
 Identities = 18/63 (28%), Positives = 27/63 (42%), Gaps = 7/63 (11%)

Query: 227  GVFCLLSDDHGASWRYGSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYH 286
            G  C LSD H   +         P G   Q  + NPD+C+  +  + +  ++    NNY 
Sbjct: 967  GGTCHLSDSHKDGFS-----CSCPLGFEGQRCEINPDDCEDNDCENNATCVD--GINNYV 1019

Query: 287  CHC 289
            C C
Sbjct: 1020 CIC 1022


>gi|91823271 xanthine dehydrogenase [Homo sapiens]
          Length = 1333

 Score = 29.3 bits (64), Expect = 6.9
 Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 7/66 (10%)

Query: 60  MEQLLWVSGRQIGSVDTFRIPLITATPRGTL--LAFAEARKMSSSDEGAKFIALRRSMDQ 117
           +EQL W +G+Q+ SV +    +ITA+P   L  +  A   K++    G      RR++  
Sbjct: 331 LEQLRWFAGKQVKSVASVGGNIITASPISDLNPVFMASGAKLTLVSRGT-----RRTVQM 385

Query: 118 GSTWSP 123
             T+ P
Sbjct: 386 DHTFFP 391


>gi|157738645 plexin A4 isoform 1 [Homo sapiens]
          Length = 1894

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 17/96 (17%)

Query: 235  DHGASWRYGSGVSGIPYGQP---KQENDFNP-DECQPYELPDGSVV------INARNQNN 284
            D    WR GSG   I   +    K END+   +    Y++PDGSVV      + A N  N
Sbjct: 1550 DMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQVTAYNAVN 1609

Query: 285  YHCHCRIVLRSYD-------ACDTLRPRDVTFDPEL 313
                 R     Y+       + D+LR R     P+L
Sbjct: 1610 NSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDL 1645


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,896,020
Number of Sequences: 37866
Number of extensions: 849300
Number of successful extensions: 1608
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1597
Number of HSP's gapped (non-prelim): 9
length of query: 415
length of database: 18,247,518
effective HSP length: 105
effective length of query: 310
effective length of database: 14,271,588
effective search space: 4424192280
effective search space used: 4424192280
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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