Guide to the Human Genome
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Search of human proteins with 45439331

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45439331 porcupine isoform B [Homo sapiens]
         (456 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45439331 porcupine isoform B [Homo sapiens]                        935   0.0  
gi|45439335 porcupine isoform D [Homo sapiens]                        929   0.0  
gi|45439333 porcupine isoform C [Homo sapiens]                        919   0.0  
gi|45439329 porcupine isoform A [Homo sapiens]                        915   0.0  
gi|45439337 porcupine isoform E [Homo sapiens]                        769   0.0  
gi|122937404 membrane bound O-acyltransferase domain containing ...    60   3e-09
gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo sapi...    60   4e-09
gi|40548387 O-acyltransferase (membrane bound) domain containing...    50   3e-06
gi|225703081 membrane bound O-acyltransferase domain containing ...    41   0.003
gi|225703079 membrane bound O-acyltransferase domain containing ...    41   0.003
gi|225703033 membrane bound O-acyltransferase domain containing ...    41   0.003
gi|225703037 membrane bound O-acyltransferase domain containing ...    37   0.049
gi|148922920 DENN/MADD domain containing 4B [Homo sapiens]             34   0.31 
gi|19424128 alkaline ceramidase 1 [Homo sapiens]                       32   0.91 
gi|52317265 olfactory receptor, family 51, subfamily I, member 2...    32   0.91 
gi|10190668 vomeronasal 1 receptor 1 [Homo sapiens]                    31   2.0  
gi|221316556 ATP-binding cassette, sub-family C, member 3 isofor...    30   4.5  
gi|9955970 ATP-binding cassette, sub-family C, member 3 isoform ...    30   4.5  
gi|4885335 G protein-coupled receptor 4 [Homo sapiens]                 30   4.5  
gi|4507147 acyl-CoA:cholesterol acyltransferase 2 [Homo sapiens]       30   5.9  
gi|164519076 transmembrane 9 superfamily protein member 4 [Homo ...    29   7.7  

>gi|45439331 porcupine isoform B [Homo sapiens]
          Length = 456

 Score =  935 bits (2416), Expect = 0.0
 Identities = 456/456 (100%), Positives = 456/456 (100%)

Query: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60
           MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG
Sbjct: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60

Query: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120
           FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW
Sbjct: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120

Query: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180
           HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV
Sbjct: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180

Query: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARWLRAY 240
           QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARWLRAY
Sbjct: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARWLRAY 240

Query: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW 300
           ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW
Sbjct: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW 300

Query: 301 NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR 360
           NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR
Sbjct: 301 NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR 360

Query: 361 KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT 420
           KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT
Sbjct: 361 KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT 420

Query: 421 EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 456
           EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG
Sbjct: 421 EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 456


>gi|45439335 porcupine isoform D [Homo sapiens]
          Length = 461

 Score =  929 bits (2400), Expect = 0.0
 Identities = 456/461 (98%), Positives = 456/461 (98%), Gaps = 5/461 (1%)

Query: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60
           MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG
Sbjct: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60

Query: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120
           FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW
Sbjct: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120

Query: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180
           HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV
Sbjct: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180

Query: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKA-----R 235
           QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKA     R
Sbjct: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARGTMVR 240

Query: 236 WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE 295
           WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE
Sbjct: 241 WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE 300

Query: 296 VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV 355
           VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV
Sbjct: 301 VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV 360

Query: 356 EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD 415
           EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD
Sbjct: 361 EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD 420

Query: 416 VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 456
           VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG
Sbjct: 421 VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 461


>gi|45439333 porcupine isoform C [Homo sapiens]
          Length = 455

 Score =  919 bits (2375), Expect = 0.0
 Identities = 451/456 (98%), Positives = 451/456 (98%), Gaps = 1/456 (0%)

Query: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60
           MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG
Sbjct: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60

Query: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120
           FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW
Sbjct: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120

Query: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180
           HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV
Sbjct: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180

Query: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARWLRAY 240
           QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR K    RWLRAY
Sbjct: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR-KGTMVRWLRAY 239

Query: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW 300
           ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW
Sbjct: 240 ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW 299

Query: 301 NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR 360
           NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR
Sbjct: 300 NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR 359

Query: 361 KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT 420
           KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT
Sbjct: 360 KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT 419

Query: 421 EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 456
           EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG
Sbjct: 420 EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 455


>gi|45439329 porcupine isoform A [Homo sapiens]
          Length = 450

 Score =  915 bits (2366), Expect = 0.0
 Identities = 449/456 (98%), Positives = 450/456 (98%), Gaps = 6/456 (1%)

Query: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60
           MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG
Sbjct: 1   MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60

Query: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120
           FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW
Sbjct: 61  FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120

Query: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180
           HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV
Sbjct: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180

Query: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARWLRAY 240
           QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR      +WLRAY
Sbjct: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR------KWLRAY 234

Query: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW 300
           ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW
Sbjct: 235 ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW 294

Query: 301 NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR 360
           NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR
Sbjct: 295 NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR 354

Query: 361 KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT 420
           KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT
Sbjct: 355 KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT 414

Query: 421 EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 456
           EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG
Sbjct: 415 EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 450


>gi|45439337 porcupine isoform E [Homo sapiens]
          Length = 379

 Score =  769 bits (1986), Expect = 0.0
 Identities = 378/385 (98%), Positives = 379/385 (98%), Gaps = 6/385 (1%)

Query: 72  MVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHKMRGAQMIVA 131
           MVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHKMRGAQMIVA
Sbjct: 1   MVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHKMRGAQMIVA 60

Query: 132 MKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQ 191
           MKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQ
Sbjct: 61  MKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQ 120

Query: 192 KVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARWLRAYESAVSFHFSNY 251
           KVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR      +WLRAYESAVSFHFSNY
Sbjct: 121 KVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR------KWLRAYESAVSFHFSNY 174

Query: 252 FVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSYWLNNY 311
           FVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSYWLNNY
Sbjct: 175 FVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSYWLNNY 234

Query: 312 VFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLARILSACV 371
           VFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLARILSACV
Sbjct: 235 VFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLARILSACV 294

Query: 372 LSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTEEQGYGMAYTV 431
           LSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTEEQGYGMAYTV
Sbjct: 295 LSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTEEQGYGMAYTV 354

Query: 432 HKWSELSWASHWVTFGCWIFYRLIG 456
           HKWSELSWASHWVTFGCWIFYRLIG
Sbjct: 355 HKWSELSWASHWVTFGCWIFYRLIG 379


>gi|122937404 membrane bound O-acyltransferase domain containing 1
           [Homo sapiens]
          Length = 495

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 80/347 (23%), Positives = 142/347 (40%), Gaps = 52/347 (14%)

Query: 49  SYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSS-HR-GVFLSVTILIY 106
           S ++HA     G + +   F  + V + +L L+CY ++     S+ HR   F+++  L  
Sbjct: 61  SDVRHAVATIFGIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTI 120

Query: 107 LLMGEMHMVDT-VTWHKMRGAQMIVAMKAVSLGFDLDRG---------------EVGTVP 150
             +  +++    +      G  MIV  K  +L F +  G                +   P
Sbjct: 121 CHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKP 180

Query: 151 SPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRP-----LSCRWLQK------------- 192
           S +E++ YL    +++ GP  +F  Y+  ++G+      L   W +K             
Sbjct: 181 SFLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFHSLPEPSPTGA 240

Query: 193 VARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARWLRAYESAVSFHFSNYF 252
           V   L + L+ L+L   +    FP    L  D  +      AR    Y    +     YF
Sbjct: 241 VIHKLGITLVSLLLFLTL-TKTFPVTC-LVDDWFVHKASFPARLCYLYVVMQASKPKYYF 298

Query: 253 VGFLSEATATLAGAGFT--EEKDHLEWDLTVSKPL-NVELPRSMVEVVTSWNLPMSYWLN 309
              L++A    AG GF+  ++  +  WDL  +  +  +E   S    + +WN+  + WL 
Sbjct: 299 AWTLADAVNNAAGFGFSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLK 358

Query: 310 NYVFKNALRLGTFSAVLVTYAASALLHG------FSFHLAAVLLSLA 350
              ++   R+  +  VL T+  SAL HG      F+F L  +L++LA
Sbjct: 359 CVCYQ---RVPWYPTVL-TFILSALWHGVYPGYYFTF-LTGILVTLA 400


>gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo
           sapiens]
          Length = 487

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 66/271 (24%), Positives = 105/271 (38%), Gaps = 35/271 (12%)

Query: 79  SLLCYLVLFLCRHSSHRGVFLSVTI----LIYLLMGEMHMVDTVTWHKMRGAQMIVAMKA 134
           SLLC ++ FL      R +   +T     + YLL G  +        K      ++ +K 
Sbjct: 93  SLLCIVLQFLILRLMGRTITAVLTTFCFQMAYLLAGYYYTATGNYDIKWTMPHCVLTLKL 152

Query: 135 VSLGFD-LDRGE-------------VGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180
           + L  D  D G+             +  VPS +E  G+ YF G  + GP  S + Y++ V
Sbjct: 153 IGLAVDYFDGGKDQNSLSSEQQKYAIRGVPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLV 212

Query: 181 QGRPLSC-----RWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKAR 235
           QG  +         +    + L+L L  LV  T + P++   ++      L  +      
Sbjct: 213 QGELIDIPGKIPNSIIPALKRLSLGLFYLVGYTLLSPHITEDYL------LTEDYDNHPF 266

Query: 236 WLRAYESAV--SFHFSNYFVGFL-SEATATLAGAGFT--EEKDHLEWDLTVS-KPLNVEL 289
           W R     +   F    Y   +L +E    L G GF   EEK   +WD   + K    E 
Sbjct: 267 WFRCMYMLIWGKFVLYKYVTCWLVTEGVCILTGLGFNGFEEKGKAKWDACANMKVWLFET 326

Query: 290 PRSMVEVVTSWNLPMSYWLNNYVFKNALRLG 320
                  + S+N+  + W+  Y+FK    LG
Sbjct: 327 NPRFTGTIASFNINTNAWVARYIFKRLKFLG 357


>gi|40548387 O-acyltransferase (membrane bound) domain containing 2
           [Homo sapiens]
          Length = 520

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 80/369 (21%), Positives = 149/369 (40%), Gaps = 54/369 (14%)

Query: 28  QIWLLLAICLACRLLWRLGLPSYLKHA-STVAGGFFSLYHFFQLHMVWVVLLSLLCYLVL 86
           Q++ LLA       L      S+++H  +T+ G + +L+ F    + ++V   +   +++
Sbjct: 32  QLFALLAAIWFRTYLHSSKTSSFIRHVVATLLGLYLALFCFGWYALHFLVQSGISYCIMI 91

Query: 87  FLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHK----MRGAQMIVAMKAVSLGFDLD 142
            +   + H   F  V  L YL + ++  V    + +      G  MI+  K  SL  ++ 
Sbjct: 92  IIGVENMHNYCF--VFALGYLTVCQVTRVYIFDYGQYSADFSGPMMIITQKITSLACEIH 149

Query: 143 RG---------------EVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSC 187
            G                V  +PS +E++ Y      I+ GP  S+  Y+  ++GR    
Sbjct: 150 DGMFRKDEELTSSQRDLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHI 209

Query: 188 RW----------LQKVARSLALALLCLVLSTCVGPYLFPYFI----PLNGDRLLRNKKRK 233
                        ++   S   A++  +L  C    LF   I    P+  + +  + +  
Sbjct: 210 TQSGENGKEETQYERTEPSPNTAVVQKLL-VCGLSLLFHLTICTTLPVEYN-IDEHFQAT 267

Query: 234 ARW----LRAYESAVSFHFSNYFVGFLSEATATLAGAGFT--EEKDHLEWDLTVSKPLN- 286
           A W    +  Y S ++     YF   L++A    AG GF   +E     WDL  +  +  
Sbjct: 268 ASWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGFRGYDENGAARWDLISNLRIQQ 327

Query: 287 VELPRSMVEVVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHG-----FSFH 341
           +E+  S    + +WN+  + WL    ++      +FS  + T+  SA+ HG     +   
Sbjct: 328 IEMSTSFKMFLDNWNIQTALWLKRVCYERT----SFSPTIQTFILSAIWHGVYPGYYLTF 383

Query: 342 LAAVLLSLA 350
           L  VL++LA
Sbjct: 384 LTGVLMTLA 392


>gi|225703081 membrane bound O-acyltransferase domain containing 7
           isoform 2 [Homo sapiens]
          Length = 399

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 62/260 (23%), Positives = 94/260 (36%), Gaps = 51/260 (19%)

Query: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199
           G +  VPS +E + Y Y    I+ GP+  + +YL    Q   G   S R L + A    L
Sbjct: 68  GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 127

Query: 200 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRNKKRKARWLRAY 240
             L  +LS+ + P                   Y+ P F            +    W+ A 
Sbjct: 128 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFR-------MRFYVAWIAAE 180

Query: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPR 291
              ++  F  Y V     A    AG G T         E+   LE+D    + ++     
Sbjct: 181 CGCIAAGFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTD 235

Query: 292 SMVEV---VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLAA 344
             V V   +  WN+ + +WL  Y++K+A           T   SA  H    G+      
Sbjct: 236 FCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLT 295

Query: 345 VLLSLAFITYVEHVLRKRLA 364
           + L LA    +E  LR RL+
Sbjct: 296 IPLCLAAEGRLESALRGRLS 315


>gi|225703079 membrane bound O-acyltransferase domain containing 7
           isoform 1 [Homo sapiens]
          Length = 472

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 62/260 (23%), Positives = 94/260 (36%), Gaps = 51/260 (19%)

Query: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199
           G +  VPS +E + Y Y    I+ GP+  + +YL    Q   G   S R L + A    L
Sbjct: 141 GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 200

Query: 200 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRNKKRKARWLRAY 240
             L  +LS+ + P                   Y+ P F            +    W+ A 
Sbjct: 201 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFR-------MRFYVAWIAAE 253

Query: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPR 291
              ++  F  Y V     A    AG G T         E+   LE+D    + ++     
Sbjct: 254 CGCIAAGFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTD 308

Query: 292 SMVEV---VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLAA 344
             V V   +  WN+ + +WL  Y++K+A           T   SA  H    G+      
Sbjct: 309 FCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLT 368

Query: 345 VLLSLAFITYVEHVLRKRLA 364
           + L LA    +E  LR RL+
Sbjct: 369 IPLCLAAEGRLESALRGRLS 388


>gi|225703033 membrane bound O-acyltransferase domain containing 7
           isoform 2 [Homo sapiens]
          Length = 399

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 62/260 (23%), Positives = 94/260 (36%), Gaps = 51/260 (19%)

Query: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199
           G +  VPS +E + Y Y    I+ GP+  + +YL    Q   G   S R L + A    L
Sbjct: 68  GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 127

Query: 200 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRNKKRKARWLRAY 240
             L  +LS+ + P                   Y+ P F            +    W+ A 
Sbjct: 128 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFR-------MRFYVAWIAAE 180

Query: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPR 291
              ++  F  Y V     A    AG G T         E+   LE+D    + ++     
Sbjct: 181 CGCIAAGFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTD 235

Query: 292 SMVEV---VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLAA 344
             V V   +  WN+ + +WL  Y++K+A           T   SA  H    G+      
Sbjct: 236 FCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLT 295

Query: 345 VLLSLAFITYVEHVLRKRLA 364
           + L LA    +E  LR RL+
Sbjct: 296 IPLCLAAEGRLESALRGRLS 315


>gi|225703037 membrane bound O-acyltransferase domain containing 7
           isoform 3 [Homo sapiens]
          Length = 344

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 49/208 (23%), Positives = 77/208 (37%), Gaps = 47/208 (22%)

Query: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199
           G +  VPS +E + Y Y    I+ GP+  + +YL    Q   G   S R L + A    L
Sbjct: 141 GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 200

Query: 200 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRNKKRKARWLRAY 240
             L  +LS+ + P                   Y+ P F            +    W+ A 
Sbjct: 201 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFR-------MRFYVAWIAAE 253

Query: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPR 291
              ++  F  Y V     A    AG G T         E+   LE+D    + ++     
Sbjct: 254 CGCIAAGFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTD 308

Query: 292 SMVEV---VTSWNLPMSYWLNNYVFKNA 316
             V V   +  WN+ + +WL  Y++K+A
Sbjct: 309 FCVRVRDGMRYWNMTVQWWLAQYIYKSA 336


>gi|148922920 DENN/MADD domain containing 4B [Homo sapiens]
          Length = 1496

 Score = 33.9 bits (76), Expect = 0.31
 Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 4/64 (6%)

Query: 32  LLAICLA--CRLLWRLGLPSYLKHASTVAGGFFSLYHFF-QLHMVWVVLLSLLCYLVLF- 87
           L A CL   C  LW L LP+Y++ A +      + YH   Q+    VVL   +CY VL  
Sbjct: 762 LWARCLLGHCYGLWFLCLPAYVRSAPSRVQALHTAYHVLRQMESGKVVLPDEVCYRVLMQ 821

Query: 88  LCRH 91
           LC H
Sbjct: 822 LCSH 825


>gi|19424128 alkaline ceramidase 1 [Homo sapiens]
          Length = 264

 Score = 32.3 bits (72), Expect = 0.91
 Identities = 14/40 (35%), Positives = 24/40 (60%), Gaps = 2/40 (5%)

Query: 41  LLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSL 80
           +LW + L S++  +  +   F+   HFF LH +W VL+S+
Sbjct: 178 VLWAVALTSWI--SDRLLCSFWQRIHFFYLHSIWHVLISI 215


>gi|52317265 olfactory receptor, family 51, subfamily I, member 2
           [Homo sapiens]
          Length = 312

 Score = 32.3 bits (72), Expect = 0.91
 Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 14/94 (14%)

Query: 294 VEVVTSWNLPMSYWLNNYVFKN-ALRLGTFSAVLVTYAASA-------------LLHGFS 339
           V V  S + PM Y+L+   F + A+ + T   VL T+  +A             L+H FS
Sbjct: 49  VRVEPSLHEPMYYFLSMLSFSDVAISMATLPTVLRTFCLNARNITFDACLIQMFLIHFFS 108

Query: 340 FHLAAVLLSLAFITYVEHVLRKRLARILSACVLS 373
              + +LL+++F  YV      R A +L+  V++
Sbjct: 109 MMESGILLAMSFDRYVAICDPLRYATVLTTEVIA 142


>gi|10190668 vomeronasal 1 receptor 1 [Homo sapiens]
          Length = 353

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 15/123 (12%)

Query: 154 EFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQKVARSLALALLCLVLSTCVGPY 213
           +F+ Y + VGT V    I   +  QA++  P  CRW++   RS      C +L  C  P+
Sbjct: 122 KFVFYYHRVGTRVSLSTICLLNGFQAIKLNPSICRWMEIKIRSPRFIDFCCLL--CWAPH 179

Query: 214 LF---PYFIPLNGDRLLRNKKRKARW----LRAYESAVSFHFSNYF------VGFLSEAT 260
           +       + +NG    +N   K  +     +A +   S H   YF      +GF+  A+
Sbjct: 180 VLMNASVLLLVNGPLNSKNSSAKNNYGYCSYKASKRFSSLHAVLYFSPDFMSLGFMVWAS 239

Query: 261 ATL 263
            ++
Sbjct: 240 GSM 242


>gi|221316556 ATP-binding cassette, sub-family C, member 3 isoform 2
           [Homo sapiens]
          Length = 572

 Score = 30.0 bits (66), Expect = 4.5
 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 4/92 (4%)

Query: 39  CRLLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHS-SHRGV 97
           C  LW + LP YL +      G+  L H  +L MV  VLL  + +  LF   H   H   
Sbjct: 42  CIYLW-VALPCYLLYLRHHCRGYIILSHLSKLKMVLGVLLWCVSWADLFYSFHGLVHGRA 100

Query: 98  FLSVTILIYLLMGEMHMVDT--VTWHKMRGAQ 127
              V  +  L++G   ++ T  + + +++G Q
Sbjct: 101 PAPVFFVTPLVVGVTMLLATLLIQYERLQGVQ 132


>gi|9955970 ATP-binding cassette, sub-family C, member 3 isoform 1
           [Homo sapiens]
          Length = 1527

 Score = 30.0 bits (66), Expect = 4.5
 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 4/92 (4%)

Query: 39  CRLLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHS-SHRGV 97
           C  LW + LP YL +      G+  L H  +L MV  VLL  + +  LF   H   H   
Sbjct: 42  CIYLW-VALPCYLLYLRHHCRGYIILSHLSKLKMVLGVLLWCVSWADLFYSFHGLVHGRA 100

Query: 98  FLSVTILIYLLMGEMHMVDT--VTWHKMRGAQ 127
              V  +  L++G   ++ T  + + +++G Q
Sbjct: 101 PAPVFFVTPLVVGVTMLLATLLIQYERLQGVQ 132


>gi|4885335 G protein-coupled receptor 4 [Homo sapiens]
          Length = 362

 Score = 30.0 bits (66), Expect = 4.5
 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 7/60 (11%)

Query: 158 YLYFVGTIVFGPW----ISFHSYLQAVQGRPLSCRWLQKVARSLALALLCLVLSTCVGPY 213
           Y  FVG +   PW    +S+   L+AV+G   + R  +   + LAL+L+ +VL  C  PY
Sbjct: 184 YRVFVGFLF--PWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVL-VCFAPY 240


>gi|4507147 acyl-CoA:cholesterol acyltransferase 2 [Homo sapiens]
          Length = 522

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 15/46 (32%), Positives = 26/46 (56%), Gaps = 4/46 (8%)

Query: 299 SWNLPMSYWLNNYVFKNALRL----GTFSAVLVTYAASALLHGFSF 340
           +WN+ +  WL +YV+++ LRL        A+L  +  SA+ H + F
Sbjct: 393 TWNVVVHDWLYSYVYQDGLRLLGARARGVAMLGVFLVSAVAHEYIF 438


>gi|164519076 transmembrane 9 superfamily protein member 4 [Homo
           sapiens]
          Length = 642

 Score = 29.3 bits (64), Expect = 7.7
 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 4/34 (11%)

Query: 415 DVDDTTEEQGYGMAYTVHKW--SELSWASHWVTF 446
           ++D T E Q Y   Y+VH W  S++ WAS W T+
Sbjct: 239 EIDPTKENQLY-FTYSVH-WEESDIKWASRWDTY 270


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.330    0.141    0.461 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,003,921
Number of Sequences: 37866
Number of extensions: 700286
Number of successful extensions: 1883
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1862
Number of HSP's gapped (non-prelim): 25
length of query: 456
length of database: 18,247,518
effective HSP length: 106
effective length of query: 350
effective length of database: 14,233,722
effective search space: 4981802700
effective search space used: 4981802700
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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