BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|45439331 porcupine isoform B [Homo sapiens] (456 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|45439331 porcupine isoform B [Homo sapiens] 935 0.0 gi|45439335 porcupine isoform D [Homo sapiens] 929 0.0 gi|45439333 porcupine isoform C [Homo sapiens] 919 0.0 gi|45439329 porcupine isoform A [Homo sapiens] 915 0.0 gi|45439337 porcupine isoform E [Homo sapiens] 769 0.0 gi|122937404 membrane bound O-acyltransferase domain containing ... 60 3e-09 gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo sapi... 60 4e-09 gi|40548387 O-acyltransferase (membrane bound) domain containing... 50 3e-06 gi|225703081 membrane bound O-acyltransferase domain containing ... 41 0.003 gi|225703079 membrane bound O-acyltransferase domain containing ... 41 0.003 gi|225703033 membrane bound O-acyltransferase domain containing ... 41 0.003 gi|225703037 membrane bound O-acyltransferase domain containing ... 37 0.049 gi|148922920 DENN/MADD domain containing 4B [Homo sapiens] 34 0.31 gi|19424128 alkaline ceramidase 1 [Homo sapiens] 32 0.91 gi|52317265 olfactory receptor, family 51, subfamily I, member 2... 32 0.91 gi|10190668 vomeronasal 1 receptor 1 [Homo sapiens] 31 2.0 gi|221316556 ATP-binding cassette, sub-family C, member 3 isofor... 30 4.5 gi|9955970 ATP-binding cassette, sub-family C, member 3 isoform ... 30 4.5 gi|4885335 G protein-coupled receptor 4 [Homo sapiens] 30 4.5 gi|4507147 acyl-CoA:cholesterol acyltransferase 2 [Homo sapiens] 30 5.9 gi|164519076 transmembrane 9 superfamily protein member 4 [Homo ... 29 7.7 >gi|45439331 porcupine isoform B [Homo sapiens] Length = 456 Score = 935 bits (2416), Expect = 0.0 Identities = 456/456 (100%), Positives = 456/456 (100%) Query: 1 MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60 MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG Sbjct: 1 MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60 Query: 61 FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120 FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW Sbjct: 61 FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120 Query: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV Sbjct: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180 Query: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARWLRAY 240 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARWLRAY Sbjct: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARWLRAY 240 Query: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW 300 ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW Sbjct: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW 300 Query: 301 NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR 360 NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR Sbjct: 301 NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR 360 Query: 361 KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT 420 KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT Sbjct: 361 KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT 420 Query: 421 EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 456 EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG Sbjct: 421 EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 456 >gi|45439335 porcupine isoform D [Homo sapiens] Length = 461 Score = 929 bits (2400), Expect = 0.0 Identities = 456/461 (98%), Positives = 456/461 (98%), Gaps = 5/461 (1%) Query: 1 MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60 MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG Sbjct: 1 MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60 Query: 61 FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120 FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW Sbjct: 61 FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120 Query: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV Sbjct: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180 Query: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKA-----R 235 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKA R Sbjct: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARGTMVR 240 Query: 236 WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE 295 WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE Sbjct: 241 WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVE 300 Query: 296 VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV 355 VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV Sbjct: 301 VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV 360 Query: 356 EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD 415 EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD Sbjct: 361 EHVLRKRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVD 420 Query: 416 VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 456 VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG Sbjct: 421 VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 461 >gi|45439333 porcupine isoform C [Homo sapiens] Length = 455 Score = 919 bits (2375), Expect = 0.0 Identities = 451/456 (98%), Positives = 451/456 (98%), Gaps = 1/456 (0%) Query: 1 MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60 MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG Sbjct: 1 MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60 Query: 61 FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120 FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW Sbjct: 61 FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120 Query: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV Sbjct: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180 Query: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARWLRAY 240 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR K RWLRAY Sbjct: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR-KGTMVRWLRAY 239 Query: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW 300 ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW Sbjct: 240 ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW 299 Query: 301 NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR 360 NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR Sbjct: 300 NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR 359 Query: 361 KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT 420 KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT Sbjct: 360 KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT 419 Query: 421 EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 456 EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG Sbjct: 420 EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 455 >gi|45439329 porcupine isoform A [Homo sapiens] Length = 450 Score = 915 bits (2366), Expect = 0.0 Identities = 449/456 (98%), Positives = 450/456 (98%), Gaps = 6/456 (1%) Query: 1 MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60 MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG Sbjct: 1 MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLACRLLWRLGLPSYLKHASTVAGG 60 Query: 61 FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120 FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW Sbjct: 61 FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW 120 Query: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV Sbjct: 121 HKMRGAQMIVAMKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180 Query: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARWLRAY 240 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR +WLRAY Sbjct: 181 QGRPLSCRWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR------KWLRAY 234 Query: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW 300 ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW Sbjct: 235 ESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSW 294 Query: 301 NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR 360 NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR Sbjct: 295 NLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLR 354 Query: 361 KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT 420 KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT Sbjct: 355 KRLARILSACVLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTT 414 Query: 421 EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 456 EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG Sbjct: 415 EEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG 450 >gi|45439337 porcupine isoform E [Homo sapiens] Length = 379 Score = 769 bits (1986), Expect = 0.0 Identities = 378/385 (98%), Positives = 379/385 (98%), Gaps = 6/385 (1%) Query: 72 MVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHKMRGAQMIVA 131 MVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHKMRGAQMIVA Sbjct: 1 MVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHKMRGAQMIVA 60 Query: 132 MKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQ 191 MKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQ Sbjct: 61 MKAVSLGFDLDRGEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQ 120 Query: 192 KVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARWLRAYESAVSFHFSNY 251 KVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR +WLRAYESAVSFHFSNY Sbjct: 121 KVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLR------KWLRAYESAVSFHFSNY 174 Query: 252 FVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSYWLNNY 311 FVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSYWLNNY Sbjct: 175 FVGFLSEATATLAGAGFTEEKDHLEWDLTVSKPLNVELPRSMVEVVTSWNLPMSYWLNNY 234 Query: 312 VFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLARILSACV 371 VFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLARILSACV Sbjct: 235 VFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYVEHVLRKRLARILSACV 294 Query: 372 LSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTEEQGYGMAYTV 431 LSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTEEQGYGMAYTV Sbjct: 295 LSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTEEQGYGMAYTV 354 Query: 432 HKWSELSWASHWVTFGCWIFYRLIG 456 HKWSELSWASHWVTFGCWIFYRLIG Sbjct: 355 HKWSELSWASHWVTFGCWIFYRLIG 379 >gi|122937404 membrane bound O-acyltransferase domain containing 1 [Homo sapiens] Length = 495 Score = 60.5 bits (145), Expect = 3e-09 Identities = 80/347 (23%), Positives = 142/347 (40%), Gaps = 52/347 (14%) Query: 49 SYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSS-HR-GVFLSVTILIY 106 S ++HA G + + F + V + +L L+CY ++ S+ HR F+++ L Sbjct: 61 SDVRHAVATIFGIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTI 120 Query: 107 LLMGEMHMVDT-VTWHKMRGAQMIVAMKAVSLGFDLDRG---------------EVGTVP 150 + +++ + G MIV K +L F + G + P Sbjct: 121 CHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKP 180 Query: 151 SPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRP-----LSCRWLQK------------- 192 S +E++ YL +++ GP +F Y+ ++G+ L W +K Sbjct: 181 SFLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFHSLPEPSPTGA 240 Query: 193 VARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARWLRAYESAVSFHFSNYF 252 V L + L+ L+L + FP L D + AR Y + YF Sbjct: 241 VIHKLGITLVSLLLFLTL-TKTFPVTC-LVDDWFVHKASFPARLCYLYVVMQASKPKYYF 298 Query: 253 VGFLSEATATLAGAGFT--EEKDHLEWDLTVSKPL-NVELPRSMVEVVTSWNLPMSYWLN 309 L++A AG GF+ ++ + WDL + + +E S + +WN+ + WL Sbjct: 299 AWTLADAVNNAAGFGFSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLK 358 Query: 310 NYVFKNALRLGTFSAVLVTYAASALLHG------FSFHLAAVLLSLA 350 ++ R+ + VL T+ SAL HG F+F L +L++LA Sbjct: 359 CVCYQ---RVPWYPTVL-TFILSALWHGVYPGYYFTF-LTGILVTLA 400 >gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo sapiens] Length = 487 Score = 60.1 bits (144), Expect = 4e-09 Identities = 66/271 (24%), Positives = 105/271 (38%), Gaps = 35/271 (12%) Query: 79 SLLCYLVLFLCRHSSHRGVFLSVTI----LIYLLMGEMHMVDTVTWHKMRGAQMIVAMKA 134 SLLC ++ FL R + +T + YLL G + K ++ +K Sbjct: 93 SLLCIVLQFLILRLMGRTITAVLTTFCFQMAYLLAGYYYTATGNYDIKWTMPHCVLTLKL 152 Query: 135 VSLGFD-LDRGE-------------VGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV 180 + L D D G+ + VPS +E G+ YF G + GP S + Y++ V Sbjct: 153 IGLAVDYFDGGKDQNSLSSEQQKYAIRGVPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLV 212 Query: 181 QGRPLSC-----RWLQKVARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKAR 235 QG + + + L+L L LV T + P++ ++ L + Sbjct: 213 QGELIDIPGKIPNSIIPALKRLSLGLFYLVGYTLLSPHITEDYL------LTEDYDNHPF 266 Query: 236 WLRAYESAV--SFHFSNYFVGFL-SEATATLAGAGFT--EEKDHLEWDLTVS-KPLNVEL 289 W R + F Y +L +E L G GF EEK +WD + K E Sbjct: 267 WFRCMYMLIWGKFVLYKYVTCWLVTEGVCILTGLGFNGFEEKGKAKWDACANMKVWLFET 326 Query: 290 PRSMVEVVTSWNLPMSYWLNNYVFKNALRLG 320 + S+N+ + W+ Y+FK LG Sbjct: 327 NPRFTGTIASFNINTNAWVARYIFKRLKFLG 357 >gi|40548387 O-acyltransferase (membrane bound) domain containing 2 [Homo sapiens] Length = 520 Score = 50.4 bits (119), Expect = 3e-06 Identities = 80/369 (21%), Positives = 149/369 (40%), Gaps = 54/369 (14%) Query: 28 QIWLLLAICLACRLLWRLGLPSYLKHA-STVAGGFFSLYHFFQLHMVWVVLLSLLCYLVL 86 Q++ LLA L S+++H +T+ G + +L+ F + ++V + +++ Sbjct: 32 QLFALLAAIWFRTYLHSSKTSSFIRHVVATLLGLYLALFCFGWYALHFLVQSGISYCIMI 91 Query: 87 FLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTWHK----MRGAQMIVAMKAVSLGFDLD 142 + + H F V L YL + ++ V + + G MI+ K SL ++ Sbjct: 92 IIGVENMHNYCF--VFALGYLTVCQVTRVYIFDYGQYSADFSGPMMIITQKITSLACEIH 149 Query: 143 RG---------------EVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSC 187 G V +PS +E++ Y I+ GP S+ Y+ ++GR Sbjct: 150 DGMFRKDEELTSSQRDLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHI 209 Query: 188 RW----------LQKVARSLALALLCLVLSTCVGPYLFPYFI----PLNGDRLLRNKKRK 233 ++ S A++ +L C LF I P+ + + + + Sbjct: 210 TQSGENGKEETQYERTEPSPNTAVVQKLL-VCGLSLLFHLTICTTLPVEYN-IDEHFQAT 267 Query: 234 ARW----LRAYESAVSFHFSNYFVGFLSEATATLAGAGFT--EEKDHLEWDLTVSKPLN- 286 A W + Y S ++ YF L++A AG GF +E WDL + + Sbjct: 268 ASWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGFRGYDENGAARWDLISNLRIQQ 327 Query: 287 VELPRSMVEVVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHG-----FSFH 341 +E+ S + +WN+ + WL ++ +FS + T+ SA+ HG + Sbjct: 328 IEMSTSFKMFLDNWNIQTALWLKRVCYERT----SFSPTIQTFILSAIWHGVYPGYYLTF 383 Query: 342 LAAVLLSLA 350 L VL++LA Sbjct: 384 LTGVLMTLA 392 >gi|225703081 membrane bound O-acyltransferase domain containing 7 isoform 2 [Homo sapiens] Length = 399 Score = 40.8 bits (94), Expect = 0.003 Identities = 62/260 (23%), Positives = 94/260 (36%), Gaps = 51/260 (19%) Query: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199 G + VPS +E + Y Y I+ GP+ + +YL Q G S R L + A L Sbjct: 68 GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 127 Query: 200 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRNKKRKARWLRAY 240 L +LS+ + P Y+ P F + W+ A Sbjct: 128 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFR-------MRFYVAWIAAE 180 Query: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPR 291 ++ F Y V A AG G T E+ LE+D + ++ Sbjct: 181 CGCIAAGFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTD 235 Query: 292 SMVEV---VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLAA 344 V V + WN+ + +WL Y++K+A T SA H G+ Sbjct: 236 FCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLT 295 Query: 345 VLLSLAFITYVEHVLRKRLA 364 + L LA +E LR RL+ Sbjct: 296 IPLCLAAEGRLESALRGRLS 315 >gi|225703079 membrane bound O-acyltransferase domain containing 7 isoform 1 [Homo sapiens] Length = 472 Score = 40.8 bits (94), Expect = 0.003 Identities = 62/260 (23%), Positives = 94/260 (36%), Gaps = 51/260 (19%) Query: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199 G + VPS +E + Y Y I+ GP+ + +YL Q G S R L + A L Sbjct: 141 GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 200 Query: 200 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRNKKRKARWLRAY 240 L +LS+ + P Y+ P F + W+ A Sbjct: 201 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFR-------MRFYVAWIAAE 253 Query: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPR 291 ++ F Y V A AG G T E+ LE+D + ++ Sbjct: 254 CGCIAAGFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTD 308 Query: 292 SMVEV---VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLAA 344 V V + WN+ + +WL Y++K+A T SA H G+ Sbjct: 309 FCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLT 368 Query: 345 VLLSLAFITYVEHVLRKRLA 364 + L LA +E LR RL+ Sbjct: 369 IPLCLAAEGRLESALRGRLS 388 >gi|225703033 membrane bound O-acyltransferase domain containing 7 isoform 2 [Homo sapiens] Length = 399 Score = 40.8 bits (94), Expect = 0.003 Identities = 62/260 (23%), Positives = 94/260 (36%), Gaps = 51/260 (19%) Query: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199 G + VPS +E + Y Y I+ GP+ + +YL Q G S R L + A L Sbjct: 68 GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 127 Query: 200 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRNKKRKARWLRAY 240 L +LS+ + P Y+ P F + W+ A Sbjct: 128 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFR-------MRFYVAWIAAE 180 Query: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPR 291 ++ F Y V A AG G T E+ LE+D + ++ Sbjct: 181 CGCIAAGFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTD 235 Query: 292 SMVEV---VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLAA 344 V V + WN+ + +WL Y++K+A T SA H G+ Sbjct: 236 FCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLT 295 Query: 345 VLLSLAFITYVEHVLRKRLA 364 + L LA +E LR RL+ Sbjct: 296 IPLCLAAEGRLESALRGRLS 315 >gi|225703037 membrane bound O-acyltransferase domain containing 7 isoform 3 [Homo sapiens] Length = 344 Score = 36.6 bits (83), Expect = 0.049 Identities = 49/208 (23%), Positives = 77/208 (37%), Gaps = 47/208 (22%) Query: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199 G + VPS +E + Y Y I+ GP+ + +YL Q G S R L + A L Sbjct: 141 GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 200 Query: 200 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRNKKRKARWLRAY 240 L +LS+ + P Y+ P F + W+ A Sbjct: 201 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFR-------MRFYVAWIAAE 253 Query: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPR 291 ++ F Y V A AG G T E+ LE+D + ++ Sbjct: 254 CGCIAAGFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTD 308 Query: 292 SMVEV---VTSWNLPMSYWLNNYVFKNA 316 V V + WN+ + +WL Y++K+A Sbjct: 309 FCVRVRDGMRYWNMTVQWWLAQYIYKSA 336 >gi|148922920 DENN/MADD domain containing 4B [Homo sapiens] Length = 1496 Score = 33.9 bits (76), Expect = 0.31 Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Query: 32 LLAICLA--CRLLWRLGLPSYLKHASTVAGGFFSLYHFF-QLHMVWVVLLSLLCYLVLF- 87 L A CL C LW L LP+Y++ A + + YH Q+ VVL +CY VL Sbjct: 762 LWARCLLGHCYGLWFLCLPAYVRSAPSRVQALHTAYHVLRQMESGKVVLPDEVCYRVLMQ 821 Query: 88 LCRH 91 LC H Sbjct: 822 LCSH 825 >gi|19424128 alkaline ceramidase 1 [Homo sapiens] Length = 264 Score = 32.3 bits (72), Expect = 0.91 Identities = 14/40 (35%), Positives = 24/40 (60%), Gaps = 2/40 (5%) Query: 41 LLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSL 80 +LW + L S++ + + F+ HFF LH +W VL+S+ Sbjct: 178 VLWAVALTSWI--SDRLLCSFWQRIHFFYLHSIWHVLISI 215 >gi|52317265 olfactory receptor, family 51, subfamily I, member 2 [Homo sapiens] Length = 312 Score = 32.3 bits (72), Expect = 0.91 Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 14/94 (14%) Query: 294 VEVVTSWNLPMSYWLNNYVFKN-ALRLGTFSAVLVTYAASA-------------LLHGFS 339 V V S + PM Y+L+ F + A+ + T VL T+ +A L+H FS Sbjct: 49 VRVEPSLHEPMYYFLSMLSFSDVAISMATLPTVLRTFCLNARNITFDACLIQMFLIHFFS 108 Query: 340 FHLAAVLLSLAFITYVEHVLRKRLARILSACVLS 373 + +LL+++F YV R A +L+ V++ Sbjct: 109 MMESGILLAMSFDRYVAICDPLRYATVLTTEVIA 142 >gi|10190668 vomeronasal 1 receptor 1 [Homo sapiens] Length = 353 Score = 31.2 bits (69), Expect = 2.0 Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 15/123 (12%) Query: 154 EFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQKVARSLALALLCLVLSTCVGPY 213 +F+ Y + VGT V I + QA++ P CRW++ RS C +L C P+ Sbjct: 122 KFVFYYHRVGTRVSLSTICLLNGFQAIKLNPSICRWMEIKIRSPRFIDFCCLL--CWAPH 179 Query: 214 LF---PYFIPLNGDRLLRNKKRKARW----LRAYESAVSFHFSNYF------VGFLSEAT 260 + + +NG +N K + +A + S H YF +GF+ A+ Sbjct: 180 VLMNASVLLLVNGPLNSKNSSAKNNYGYCSYKASKRFSSLHAVLYFSPDFMSLGFMVWAS 239 Query: 261 ATL 263 ++ Sbjct: 240 GSM 242 >gi|221316556 ATP-binding cassette, sub-family C, member 3 isoform 2 [Homo sapiens] Length = 572 Score = 30.0 bits (66), Expect = 4.5 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 4/92 (4%) Query: 39 CRLLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHS-SHRGV 97 C LW + LP YL + G+ L H +L MV VLL + + LF H H Sbjct: 42 CIYLW-VALPCYLLYLRHHCRGYIILSHLSKLKMVLGVLLWCVSWADLFYSFHGLVHGRA 100 Query: 98 FLSVTILIYLLMGEMHMVDT--VTWHKMRGAQ 127 V + L++G ++ T + + +++G Q Sbjct: 101 PAPVFFVTPLVVGVTMLLATLLIQYERLQGVQ 132 >gi|9955970 ATP-binding cassette, sub-family C, member 3 isoform 1 [Homo sapiens] Length = 1527 Score = 30.0 bits (66), Expect = 4.5 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 4/92 (4%) Query: 39 CRLLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHS-SHRGV 97 C LW + LP YL + G+ L H +L MV VLL + + LF H H Sbjct: 42 CIYLW-VALPCYLLYLRHHCRGYIILSHLSKLKMVLGVLLWCVSWADLFYSFHGLVHGRA 100 Query: 98 FLSVTILIYLLMGEMHMVDT--VTWHKMRGAQ 127 V + L++G ++ T + + +++G Q Sbjct: 101 PAPVFFVTPLVVGVTMLLATLLIQYERLQGVQ 132 >gi|4885335 G protein-coupled receptor 4 [Homo sapiens] Length = 362 Score = 30.0 bits (66), Expect = 4.5 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 7/60 (11%) Query: 158 YLYFVGTIVFGPW----ISFHSYLQAVQGRPLSCRWLQKVARSLALALLCLVLSTCVGPY 213 Y FVG + PW +S+ L+AV+G + R + + LAL+L+ +VL C PY Sbjct: 184 YRVFVGFLF--PWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVL-VCFAPY 240 >gi|4507147 acyl-CoA:cholesterol acyltransferase 2 [Homo sapiens] Length = 522 Score = 29.6 bits (65), Expect = 5.9 Identities = 15/46 (32%), Positives = 26/46 (56%), Gaps = 4/46 (8%) Query: 299 SWNLPMSYWLNNYVFKNALRL----GTFSAVLVTYAASALLHGFSF 340 +WN+ + WL +YV+++ LRL A+L + SA+ H + F Sbjct: 393 TWNVVVHDWLYSYVYQDGLRLLGARARGVAMLGVFLVSAVAHEYIF 438 >gi|164519076 transmembrane 9 superfamily protein member 4 [Homo sapiens] Length = 642 Score = 29.3 bits (64), Expect = 7.7 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 4/34 (11%) Query: 415 DVDDTTEEQGYGMAYTVHKW--SELSWASHWVTF 446 ++D T E Q Y Y+VH W S++ WAS W T+ Sbjct: 239 EIDPTKENQLY-FTYSVH-WEESDIKWASRWDTY 270 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.330 0.141 0.461 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,003,921 Number of Sequences: 37866 Number of extensions: 700286 Number of successful extensions: 1883 Number of sequences better than 10.0: 21 Number of HSP's better than 10.0 without gapping: 7 Number of HSP's successfully gapped in prelim test: 14 Number of HSP's that attempted gapping in prelim test: 1862 Number of HSP's gapped (non-prelim): 25 length of query: 456 length of database: 18,247,518 effective HSP length: 106 effective length of query: 350 effective length of database: 14,233,722 effective search space: 4981802700 effective search space used: 4981802700 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.9 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.