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Search of human proteins with 4507943
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507943 exportin 1 [Homo sapiens]
(1071 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507943 exportin 1 [Homo sapiens] 2145 0.0
gi|22748937 exportin 5 [Homo sapiens] 73 1e-12
gi|224831257 importin 13 [Homo sapiens] 72 4e-12
gi|46049063 exportin 6 [Homo sapiens] 44 6e-04
gi|209969838 transportin 2 (importin 3, karyopherin beta 2b) iso... 38 0.058
gi|209969836 transportin 2 (importin 3, karyopherin beta 2b) iso... 38 0.058
gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isof... 38 0.058
gi|29029559 CSE1 chromosome segregation 1-like protein [Homo sap... 37 0.100
gi|23510381 transportin 1 isoform 2 [Homo sapiens] 36 0.17
gi|133925811 transportin 1 isoform 1 [Homo sapiens] 36 0.17
gi|6912734 transportin 3 [Homo sapiens] 35 0.50
gi|94966752 elongation factor Tu GTP binding domain containing 1... 33 1.1
gi|94966754 elongation factor Tu GTP binding domain containing 1... 33 1.1
gi|41327749 anaphase-promoting complex subunit 4 [Homo sapiens] 32 2.5
gi|154448896 exportin 7 isoform c [Homo sapiens] 32 4.2
gi|154448892 exportin 7 isoform b [Homo sapiens] 32 4.2
gi|56237018 testis and skeletal muscle-specific dual specificity... 31 5.5
gi|56117822 testis and skeletal muscle-specific dual specificity... 31 5.5
gi|56117820 testis and skeletal muscle-specific dual specificity... 31 5.5
gi|212549536 regulator of G-protein signaling like 1 [Homo sapiens] 31 5.5
gi|11641245 kinesin family member 9 isoform 1 [Homo sapiens] 30 9.3
gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription facto... 30 9.3
>gi|4507943 exportin 1 [Homo sapiens]
Length = 1071
Score = 2145 bits (5558), Expect = 0.0
Identities = 1071/1071 (100%), Positives = 1071/1071 (100%)
Query: 1 MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAW 60
MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAW
Sbjct: 1 MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAW 60
Query: 61 TRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCV 120
TRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCV
Sbjct: 61 TRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCV 120
Query: 121 EKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFD 180
EKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFD
Sbjct: 121 EKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFD 180
Query: 181 FSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGY 240
FSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGY
Sbjct: 181 FSSGQITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGY 240
Query: 241 IFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPL 300
IFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPL
Sbjct: 241 IFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPL 300
Query: 301 NTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVSEV 360
NTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVSEV
Sbjct: 301 NTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVSEV 360
Query: 361 EETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPRRQLYLPMLFKVRLLM 420
EETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPRRQLYLPMLFKVRLLM
Sbjct: 361 EETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPRRQLYLPMLFKVRLLM 420
Query: 421 VSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTERIMTEKL 480
VSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTERIMTEKL
Sbjct: 421 VSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTERIMTEKL 480
Query: 481 HNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAII 540
HNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAII
Sbjct: 481 HNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAII 540
Query: 541 ASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFV 600
ASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFV
Sbjct: 541 ASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFV 600
Query: 601 QVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLL 660
QVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLL
Sbjct: 601 QVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLL 660
Query: 661 PNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNV 720
PNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNV
Sbjct: 661 PNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNV 720
Query: 721 YKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPL 780
YKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPL
Sbjct: 721 YKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPL 780
Query: 781 LDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEE 840
LDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEE
Sbjct: 781 LDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEE 840
Query: 841 YPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTL 900
YPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTL
Sbjct: 841 YPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTL 900
Query: 901 LQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKIST 960
LQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKIST
Sbjct: 901 LQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKIST 960
Query: 961 SLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLV 1020
SLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLV
Sbjct: 961 SLNPGNPVNNQIFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLV 1020
Query: 1021 QIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD 1071
QIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD
Sbjct: 1021 QIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD 1071
>gi|22748937 exportin 5 [Homo sapiens]
Length = 1204
Score = 73.2 bits (178), Expect = 1e-12
Identities = 50/194 (25%), Positives = 97/194 (50%), Gaps = 22/194 (11%)
Query: 66 ILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCVEKEKV 125
+ E +Q +++GLQILE+V+K RW + R + +K V+ LI + + +E+E
Sbjct: 54 LAEKTQVAIVRHFGLQILEHVVKFRWNGMSRLEKVYLKNSVMELIANGTLN--ILEEENH 111
Query: 126 YIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFDFSSGQ 185
L+ I+V+++K+EWP+HWP + ++ S+ E+ + M IL L+E+V F +
Sbjct: 112 IKDALSRIVVEMIKREWPQHWPDMLIELDTLSKQGETQTELVMFILLRLAEDVVTFQT-- 169
Query: 186 ITQVKSKHLKDSMCNEFSQIFQ-LCQFVMEN-----------------SQNAPLVHATLE 227
+ + + ++ ++ +IF L + EN N + A L
Sbjct: 170 LPPQRRRDIQQTLTQNMERIFSFLLNTLQENVNKYQQVKTDTSQESKAQANCRVGVAALN 229
Query: 228 TLLRFLNWIPLGYI 241
TL +++W+ + +I
Sbjct: 230 TLAGYIDWVSMSHI 243
>gi|224831257 importin 13 [Homo sapiens]
Length = 963
Score = 71.6 bits (174), Expect = 4e-12
Identities = 125/700 (17%), Positives = 275/700 (39%), Gaps = 85/700 (12%)
Query: 9 ADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQR-MAQEVLTHLKEHPDAWTRVDTIL 67
A A LDF+ + ++ ++ LY+ + + +AQ+ L + P AW +L
Sbjct: 11 AGAGAAPALDFT----VENVEKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWHFSWQLL 66
Query: 68 EFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCVEKEKVYI 127
+ + +Y+G L I W +P +Q E +K + I + +S K+ +
Sbjct: 67 QPDKVPEIQYFGASALHIKISRYWSDIPTDQYESLKAQLFTQITRFASG------SKIVL 120
Query: 128 GKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNN---MVILKLLSEEVFDFSSG 184
+L + L + P WP ++D+V + +S + +L+LL+ +F +
Sbjct: 121 TRLCVALASLALSMMPDAWPCAVADMVRLFQAEDSPVDGQGRCLALLELLTVLPEEFQTS 180
Query: 185 QITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGYIFE- 243
++ Q + ++ S+ E +F L + +++ + V + L F +W+ L +
Sbjct: 181 RLPQYRKGLVRTSLAVECGAVFPLLEQLLQQPSSPSCVRQ--KVLKCFSSWVQLEVPLQD 238
Query: 244 -TKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPLNT 302
LI + +F + + I+ +Y + L L +L L
Sbjct: 239 CEALIQAAFAALQDSELFDSSVEAIVNAISQPDAQRYVNTLLKLIPL-------VLGLQE 291
Query: 303 NIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVS---- 358
+R A NG + + I +++ L + H + + ++ ++ + ++ ++ +
Sbjct: 292 QLRQAVQNGDMETSHGICRIAVALG---ENHSRALLDQVEHWQSFLALVNMIMFCTGIPG 348
Query: 359 --EVEETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPRRQLYLPMLFKV 416
V ET + L +W L ++ F + +Q+Y P+ F++
Sbjct: 349 HYPVNET-TSSLTLTFWYTLQDDIL---SFEAEKQAVY-----------QQVYRPVYFQL 393
Query: 417 --RLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTER 474
LL ++ EE +D+ E R + D + +TL+Y+ + +
Sbjct: 394 VDVLLHKAQFPSDEEYGFWSSDEKEQFRIYRVD---------ISDTLMYVYEMLGAELLS 444
Query: 475 IMTEKLHNQVNGTE--WSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKR 532
+ +KL + +E +SW++ L + SI+ + V+ L+GL R
Sbjct: 445 NLYDKLGRLLTSSEEPYSWQHTEALLYGFQSIAETIDVN-----YSDVVPGLIGLI--PR 497
Query: 533 GKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIA 592
+ +A +M+ +G +L H + +V+ + + V ++ T KI
Sbjct: 498 ISISNVQLADTVMFTIGALSEWLADHPVMINSVLPLVLHALGNPELSVSSVS--TLKKIC 555
Query: 593 QKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEH 652
++C+ V D ++ I+ + Q +A+G+++ A + + ++
Sbjct: 556 RECKYDLPPYAANIVAVSQDVLMKQIH------KTSQCMWLMQALGFLLSALQVEEILKN 609
Query: 653 LIEKYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSIL 692
L + + IQQ K + + +P + IL
Sbjct: 610 L--------HSLISPYIQQLEKLAEEIPNPSNKLAIVHIL 641
>gi|46049063 exportin 6 [Homo sapiens]
Length = 1125
Score = 44.3 bits (103), Expect = 6e-04
Identities = 69/395 (17%), Positives = 147/395 (37%), Gaps = 86/395 (21%)
Query: 20 SQKLDINLLDNVVNCLYHG--EGAQQRMAQEVLTHLKEHPDAWTRVDTILEFSQNMNTKY 77
S++ + L++++ +H ++R +E+L + + AW L ++N
Sbjct: 3 SEEASLRALESLMTEFFHDCTTNERKREIEELLNNFAQQIGAWRFCLYFLSSTRNDYVMM 62
Query: 78 YGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCVEKEKVYI--GKLNMILV 135
Y L + EN+I W +P I+ + L++ K Y KL ++V
Sbjct: 63 YSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLL-------AHHKTLPYFIRNKLCKVIV 115
Query: 136 QILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFDFSSGQITQVKSKHLK 195
I +Q+WP + F ++I+ + S +++LK SEE+ ++ + + L+
Sbjct: 116 DIGRQDWPMFYHDFFTNILQLIQ-SPVTTPLGLIMLKTTSEEL-ACPREDLSVARKEELR 173
Query: 196 DSMCNEFSQIFQLCQFVMEN--------------------------------------SQ 217
+ ++ + L ++E +Q
Sbjct: 174 KLLLDQVQTVLGLLTGILETVWDKHSVTAATPPPSPTSGESGDLLSNLLQSPSSAKLLNQ 233
Query: 218 NAPLVHA--------TLETLLRFLNWIPLGYIFETKLISTLIY-----------KFLNV- 257
P++ LE L +WIPL L++T+ + K +V
Sbjct: 234 PIPILDVESEYICSLALECLAHLFSWIPLSASITPSLLTTIFHFARFGCDIRARKMASVN 293
Query: 258 ------------PMFRNVSLKCLTEIAGVSV--SQYEEQFVTLFTLTMMQLKQMLPLNTN 303
+++ C+ E+ + ++EE + +F T L Q + + N
Sbjct: 294 GSSQNCVSGQERGRLGVLAMSCINELMSKNCVPMEFEEYLLRMFQQT-FYLLQKITKDNN 352
Query: 304 IRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIE 338
S ++ ++++I+ + FL F+ H + IE
Sbjct: 353 AHTVKSRLEELDESYIEKFTDFLRLFVSVHLRRIE 387
>gi|209969838 transportin 2 (importin 3, karyopherin beta 2b)
isoform 1 [Homo sapiens]
Length = 897
Score = 37.7 bits (86), Expect = 0.058
Identities = 30/141 (21%), Positives = 61/141 (43%), Gaps = 20/141 (14%)
Query: 535 DNKAIIASNIMYIVGQYPRFLRAHW-------KFLKTVVNKLFEFMHETHDGVQDMACDT 587
D KA++ S + + +Y AHW LK ++ +L + + + + VQ+ AC
Sbjct: 446 DKKALVRSIACWTLSRY-----AHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSA 500
Query: 588 FIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQ 647
F + ++ E++P++ IL+ + Q + + Y+A+G + +
Sbjct: 501 FATLEEEA--------CTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHH 552
Query: 648 TVQEHLIEKYMLLPNQVWDSI 668
Q I+K M Q W+ +
Sbjct: 553 LNQPEYIQKLMPPLIQKWNEL 573
>gi|209969836 transportin 2 (importin 3, karyopherin beta 2b)
isoform 3 [Homo sapiens]
Length = 887
Score = 37.7 bits (86), Expect = 0.058
Identities = 30/141 (21%), Positives = 61/141 (43%), Gaps = 20/141 (14%)
Query: 535 DNKAIIASNIMYIVGQYPRFLRAHW-------KFLKTVVNKLFEFMHETHDGVQDMACDT 587
D KA++ S + + +Y AHW LK ++ +L + + + + VQ+ AC
Sbjct: 446 DKKALVRSIACWTLSRY-----AHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSA 500
Query: 588 FIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQ 647
F + ++ E++P++ IL+ + Q + + Y+A+G + +
Sbjct: 501 FATLEEEA--------CTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHH 552
Query: 648 TVQEHLIEKYMLLPNQVWDSI 668
Q I+K M Q W+ +
Sbjct: 553 LNQPEYIQKLMPPLIQKWNEL 573
>gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isoform
2 [Homo sapiens]
Length = 887
Score = 37.7 bits (86), Expect = 0.058
Identities = 30/141 (21%), Positives = 61/141 (43%), Gaps = 20/141 (14%)
Query: 535 DNKAIIASNIMYIVGQYPRFLRAHW-------KFLKTVVNKLFEFMHETHDGVQDMACDT 587
D KA++ S + + +Y AHW LK ++ +L + + + + VQ+ AC
Sbjct: 446 DKKALVRSIACWTLSRY-----AHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSA 500
Query: 588 FIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQ 647
F + ++ E++P++ IL+ + Q + + Y+A+G + +
Sbjct: 501 FATLEEEA--------CTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHH 552
Query: 648 TVQEHLIEKYMLLPNQVWDSI 668
Q I+K M Q W+ +
Sbjct: 553 LNQPEYIQKLMPPLIQKWNEL 573
>gi|29029559 CSE1 chromosome segregation 1-like protein [Homo
sapiens]
Length = 971
Score = 37.0 bits (84), Expect = 0.100
Identities = 48/221 (21%), Positives = 98/221 (44%), Gaps = 24/221 (10%)
Query: 41 AQQRMAQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYGLQILENVIKTRWKIL---PRN 97
A +R A++ L ++ + + + T+LE SQ+ K +N IK W+I+ P
Sbjct: 24 AIRRPAEKFLESVEGNQNYPLLLLTLLEKSQDNVIKVCASVTFKNYIKRNWRIVEDEPNK 83
Query: 98 QCE----GIKKYVVGLIIKTSSDPTCVEKEKVYIGKLNMILVQILKQEWPKHWPTFISDI 153
CE IK +V L++ S P ++K+ L+ + I ++++P+ WP ++++
Sbjct: 84 ICEADRVAIKANIVHLML---SSPEQIQKQ------LSDAISIIGREDFPQKWPDLLTEM 134
Query: 154 VGASRTSESLCQNNMV--ILKLLSEEVFDFSSGQI-TQVK--SKHLKDSMCNEFSQIFQL 208
V ++ + N ++ L +F S ++ T++K + N F +L
Sbjct: 135 VNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIEL 194
Query: 209 CQFVMENSQNAPLVHATL---ETLLRFLNWIPLGYIFETKL 246
C ++ ++ ++L L LN+ L FE +
Sbjct: 195 CSTHANDASALRILFSSLILISKLFYSLNFQDLPEFFEDNM 235
>gi|23510381 transportin 1 isoform 2 [Homo sapiens]
Length = 890
Score = 36.2 bits (82), Expect = 0.17
Identities = 29/144 (20%), Positives = 66/144 (45%), Gaps = 28/144 (19%)
Query: 535 DNKAIIASNIMYIVGQYPRFLRAHW-------KFLKTVVNKLFEFMHETHDGVQDMACDT 587
D KA++ S + + +Y AHW +LK ++ +L + + +++ VQ+ AC
Sbjct: 449 DKKALVRSITCWTLSRY-----AHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSA 503
Query: 588 FIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGA---- 643
F + ++ E++P++ IL+ + Q + + Y+A+G + +
Sbjct: 504 FATLEEEA--------CTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHH 555
Query: 644 ----QTDQTVQEHLIEKYMLLPNQ 663
+ Q + LI+K+ +L ++
Sbjct: 556 LNKPEYIQMLMPPLIQKWNMLKDE 579
>gi|133925811 transportin 1 isoform 1 [Homo sapiens]
Length = 898
Score = 36.2 bits (82), Expect = 0.17
Identities = 29/144 (20%), Positives = 66/144 (45%), Gaps = 28/144 (19%)
Query: 535 DNKAIIASNIMYIVGQYPRFLRAHW-------KFLKTVVNKLFEFMHETHDGVQDMACDT 587
D KA++ S + + +Y AHW +LK ++ +L + + +++ VQ+ AC
Sbjct: 457 DKKALVRSITCWTLSRY-----AHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSA 511
Query: 588 FIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGA---- 643
F + ++ E++P++ IL+ + Q + + Y+A+G + +
Sbjct: 512 FATLEEEA--------CTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHH 563
Query: 644 ----QTDQTVQEHLIEKYMLLPNQ 663
+ Q + LI+K+ +L ++
Sbjct: 564 LNKPEYIQMLMPPLIQKWNMLKDE 587
>gi|6912734 transportin 3 [Homo sapiens]
Length = 923
Score = 34.7 bits (78), Expect = 0.50
Identities = 74/369 (20%), Positives = 142/369 (38%), Gaps = 26/369 (7%)
Query: 22 KLDINLLDNVVNCLYHG-EGAQQRMAQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYGL 80
K + L+ V LYH + + + A L L+ AW D +L+ Q++ + Y+
Sbjct: 5 KPTLQLVYQAVQALYHDPDPSGKERASFWLGELQRSVHAWEISDQLLQIRQDVESCYFAA 64
Query: 81 QILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCVEKEKVYIGKLNMILVQILKQ 140
Q ++ I+T + LP + ++ ++ I + V + +L + + + Q
Sbjct: 65 QTMKMKIQTSFYELPTDSHASLRDSLLTHIQNLK------DLSPVIVTQLALAIADLALQ 118
Query: 141 EWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFDFSSGQITQVKSKHLKDSMCN 200
W + +V + + IL +L EEV S +I + + + +
Sbjct: 119 M--PSWKGCVQTLVEKYSNDVTSLPFLLEILTVLPEEVHSRSL-RIGANRRTEIIEDLAF 175
Query: 201 EFSQIFQLCQFVMENSQNAPLVHATLETLLRFL-NWIPLGYIFETKLISTLIYKFLNVPM 259
S + L +E A L + R L +W LG + + + + L +
Sbjct: 176 YSSTVVSLLMTCVEK---AGTDEKMLMKVFRCLGSWFNLGVLDSNFMANNKLLALLFEVL 232
Query: 260 FRNVSLKCLTEIAG---VSVSQYEEQFVTLFTLTMMQLKQMLPLNTNIRLAYSNGKDDEQ 316
++ + L E A S E T L M + +L L T +A + ++D
Sbjct: 233 QQDKTSSNLHEAASDCVCSALYAIENVETNLPLAMQLFQGVLTLETAYHMAVA--REDLD 290
Query: 317 NFIQNLSLF--LC-TFLKEHDQLIEKRLNLRETLMEALHYMLLVSEVEETEIFKICLEYW 373
+ +F LC TFL++ + L TL +L+ + + E+ +I +W
Sbjct: 291 KVLNYCRIFTELCETFLEKIVCTPGQGLGDLRTL----ELLLICAGHPQYEVVEISFNFW 346
Query: 374 NHLAAELYR 382
L LY+
Sbjct: 347 YRLGEHLYK 355
>gi|94966752 elongation factor Tu GTP binding domain containing 1
isoform 2 [Homo sapiens]
Length = 1069
Score = 33.5 bits (75), Expect = 1.1
Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 13/91 (14%)
Query: 415 KVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTER 474
K+ L V M PEEV + + +++R + T S+N +N TH+ + T+
Sbjct: 696 KLATLSVRAMPLPEEVTQILEENSDLIRSMEQLTSSLNEGEN--------THMIHQKTQE 747
Query: 475 IMTE---KLHNQVNGTEWSWKNLNTLCWAIG 502
+ E KL + G W+N+ W+ G
Sbjct: 748 KIWEFKGKLEQHLTGRR--WRNIVDQIWSFG 776
>gi|94966754 elongation factor Tu GTP binding domain containing 1
isoform 1 [Homo sapiens]
Length = 1120
Score = 33.5 bits (75), Expect = 1.1
Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 13/91 (14%)
Query: 415 KVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTER 474
K+ L V M PEEV + + +++R + T S+N +N TH+ + T+
Sbjct: 747 KLATLSVRAMPLPEEVTQILEENSDLIRSMEQLTSSLNEGEN--------THMIHQKTQE 798
Query: 475 IMTE---KLHNQVNGTEWSWKNLNTLCWAIG 502
+ E KL + G W+N+ W+ G
Sbjct: 799 KIWEFKGKLEQHLTGRR--WRNIVDQIWSFG 827
>gi|41327749 anaphase-promoting complex subunit 4 [Homo sapiens]
Length = 808
Score = 32.3 bits (72), Expect = 2.5
Identities = 38/177 (21%), Positives = 69/177 (38%), Gaps = 39/177 (22%)
Query: 859 CFPAFLAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTLL------------QNVAQ 906
CFP+F + Q + ++W+ K + +A+T ++L L +N +
Sbjct: 7 CFPSFRVVGEKQLPQEIIFLVWSPKRDLIALANTAGEVLLHRLASFHRVWSFPPNENTGK 66
Query: 907 EEA-------------AAQSFYQTYFCDILQ----HIFSVVTDTS--HTAGLTMHASILA 947
E A + CD+ + H FSV S H +T+ +S+L
Sbjct: 67 EVTCLAWRPDGKLLAFALADTKKIVLCDVEKPESLHSFSVEAPVSCMHWMEVTVESSVLT 126
Query: 948 YMFNLVEEGKISTSLNPGNPVN----NQIFLQEYVANLLKSAFPHLQDAQVKLFVTG 1000
+N +E + P P N ++IF +E ++K L D ++ + V G
Sbjct: 127 SFYNAEDESNLLLPKLPTLPKNYSNTSKIFSEENSDEIIKL----LGDVRLNILVLG 179
>gi|154448896 exportin 7 isoform c [Homo sapiens]
Length = 1088
Score = 31.6 bits (70), Expect = 4.2
Identities = 36/185 (19%), Positives = 70/185 (37%), Gaps = 10/185 (5%)
Query: 28 LDNVVNCLYHGEGAQQRM-AQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYGLQILENV 86
L+N+ LY R+ A++ L PD ++ +LE + ++ L +
Sbjct: 12 LENLCKQLYETTDTTTRLQAEKALVEFTNSPDCLSKCQLLLERGSSSYSQLLAATCLTKL 71
Query: 87 IKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCVEKEKVYIGKLNMILVQILKQEW---P 143
+ LP Q I+ YV+ + T V + L + +I K W
Sbjct: 72 VSRTNNPLPLEQRIDIRNYVLNYLATRPKLATFVTQ------ALIQLYARITKLGWFDCQ 125
Query: 144 KHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFDFSSGQITQVKSKHLKDSMCNEFS 203
K F + I +R + + ++ + +LS+ + + T +KH K + S
Sbjct: 126 KDDYVFRNAITDVTRFLQDSVEYCIIGVTILSQLTNEINQADTTHPLTKHRKIASSFRDS 185
Query: 204 QIFQL 208
+F +
Sbjct: 186 SLFDI 190
>gi|154448892 exportin 7 isoform b [Homo sapiens]
Length = 1087
Score = 31.6 bits (70), Expect = 4.2
Identities = 36/185 (19%), Positives = 70/185 (37%), Gaps = 10/185 (5%)
Query: 28 LDNVVNCLYHGEGAQQRM-AQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYGLQILENV 86
L+N+ LY R+ A++ L PD ++ +LE + ++ L +
Sbjct: 11 LENLCKQLYETTDTTTRLQAEKALVEFTNSPDCLSKCQLLLERGSSSYSQLLAATCLTKL 70
Query: 87 IKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCVEKEKVYIGKLNMILVQILKQEW---P 143
+ LP Q I+ YV+ + T V + L + +I K W
Sbjct: 71 VSRTNNPLPLEQRIDIRNYVLNYLATRPKLATFVTQ------ALIQLYARITKLGWFDCQ 124
Query: 144 KHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFDFSSGQITQVKSKHLKDSMCNEFS 203
K F + I +R + + ++ + +LS+ + + T +KH K + S
Sbjct: 125 KDDYVFRNAITDVTRFLQDSVEYCIIGVTILSQLTNEINQADTTHPLTKHRKIASSFRDS 184
Query: 204 QIFQL 208
+F +
Sbjct: 185 SLFDI 189
>gi|56237018 testis and skeletal muscle-specific dual specificity
phosphatase isoform 6 [Homo sapiens]
Length = 198
Score = 31.2 bits (69), Expect = 5.5
Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 4/76 (5%)
Query: 14 RQLLDFSQKLDINLLDNVVNCLYHGEGAQQR----MAQEVLTHLKEHPDAWTRVDTILEF 69
++LL Q +N +D V L+ G+ R + Q +TH+ +VDT +F
Sbjct: 32 QRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKF 91
Query: 70 SQNMNTKYYGLQILEN 85
+ M+ +YYG++ +N
Sbjct: 92 YRGMSLEYYGIEADDN 107
>gi|56117822 testis and skeletal muscle-specific dual specificity
phosphatase isoform 3 [Homo sapiens]
Length = 291
Score = 31.2 bits (69), Expect = 5.5
Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 4/76 (5%)
Query: 14 RQLLDFSQKLDINLLDNVVNCLYHGEGAQQR----MAQEVLTHLKEHPDAWTRVDTILEF 69
++LL Q +N +D V L+ G+ R + Q +TH+ +VDT +F
Sbjct: 125 QRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKF 184
Query: 70 SQNMNTKYYGLQILEN 85
+ M+ +YYG++ +N
Sbjct: 185 YRGMSLEYYGIEADDN 200
>gi|56117820 testis and skeletal muscle-specific dual specificity
phosphatase isoform 2 [Homo sapiens]
Length = 248
Score = 31.2 bits (69), Expect = 5.5
Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 4/76 (5%)
Query: 14 RQLLDFSQKLDINLLDNVVNCLYHGEGAQQR----MAQEVLTHLKEHPDAWTRVDTILEF 69
++LL Q +N +D V L+ G+ R + Q +TH+ +VDT +F
Sbjct: 82 QRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKF 141
Query: 70 SQNMNTKYYGLQILEN 85
+ M+ +YYG++ +N
Sbjct: 142 YRGMSLEYYGIEADDN 157
>gi|212549536 regulator of G-protein signaling like 1 [Homo sapiens]
Length = 1076
Score = 31.2 bits (69), Expect = 5.5
Identities = 37/165 (22%), Positives = 70/165 (42%), Gaps = 19/165 (11%)
Query: 69 FSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCVEKEKV-YI 127
F+ ++ +G V ++W + P C I KY GL+ T +EK ++ +
Sbjct: 25 FNTFLSLPVFGQTPFYTVENSQWSLWPEIPCNLIAKY-KGLL-------TWLEKCRLPFF 76
Query: 128 GKLNMILVQILKQEWPKHWPTFISDIVGASRTSES-LCQNNMVILKLLSEEVFDFSSGQI 186
K N+ IL QE + +FI G + + N++ + + EV D+ +
Sbjct: 77 CKTNLCFHYILCQE----FISFIKSPEGGEELVDFWILAENILSIDEMDLEVRDYYLSLL 132
Query: 187 TQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLR 231
+++ HL+ E S++ LC +++ N + H T R
Sbjct: 133 LMLRATHLQ-----EGSRVVTLCNMNIKSLLNLSIWHPNQSTTRR 172
>gi|11641245 kinesin family member 9 isoform 1 [Homo sapiens]
Length = 725
Score = 30.4 bits (67), Expect = 9.3
Identities = 55/246 (22%), Positives = 98/246 (39%), Gaps = 30/246 (12%)
Query: 285 TLFTLTMMQLKQMLPLNTNIRLAYSNGKDDEQNFI---QNLSLF--LCTFLKEHDQLIEK 339
T T M Q+ +N+ +R Y G DE + I Q +F L + +Q +E
Sbjct: 380 TFVTYDPMDEIQIAEINSQVR-RYLEGTLDEIDIISLRQIKEVFNQFRVVLSQQEQEVES 438
Query: 340 RLNLRETLMEALHYMLLVSEVEETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQH 399
L + TL++ + +S +++ + + HL E ++ F +P
Sbjct: 439 TLRRKYTLIDRNDFAA-ISAIQKAGLVDVD----GHLVGEPEGQN-FGLGVAP------- 485
Query: 400 FDVPPRRQLYLPMLFKVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRE 459
F P ++ FK L + +KP +N+QG + K+ SI L + +
Sbjct: 486 FSTKPGKKAKSKKTFKEPLRPDTPPSKPVAFEEFKNEQGSEINRIFKENKSI-LNERRKR 544
Query: 460 TLVYLTHLDYVDTERIMT-EKLHNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLV 518
H++ + E +T E L+ Q + E K N G M ++E+ L+
Sbjct: 545 ASETTQHINAIKREIDVTKEALNFQKSLREKQGKYEN---------KGLMIIDEEEFLLI 595
Query: 519 TVIKDL 524
+KDL
Sbjct: 596 LKLKDL 601
>gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription
factor-associated, 170kDa [Homo sapiens]
Length = 1849
Score = 30.4 bits (67), Expect = 9.3
Identities = 27/113 (23%), Positives = 52/113 (46%), Gaps = 11/113 (9%)
Query: 816 TAEIPQIFDAVFECTLNMINKDFEEYPEHRTNFFLLLQAVNSHCFPAFLAIPPTQFKLVL 875
T ++P I + +++ L + ++ + LL ++ + +P Q VL
Sbjct: 466 TQKVPFIINTLWDALLEL-----DDLTASTNSIMTLLSSLLT--YPQVQQCSIQQSLTVL 518
Query: 876 DSIIWAF-KHTMRNVADTGLQILFTLLQNVAQEEAAAQSFYQTYFCDILQHIF 927
+W F HT+ +V L+ LFTLL + ++ + S+ D+L+HIF
Sbjct: 519 VPRVWPFLHHTISSVRRAALETLFTLL---STQDQNSSSWLIPILPDMLRHIF 568
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,073,969
Number of Sequences: 37866
Number of extensions: 1543938
Number of successful extensions: 3676
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 3660
Number of HSP's gapped (non-prelim): 40
length of query: 1071
length of database: 18,247,518
effective HSP length: 113
effective length of query: 958
effective length of database: 13,968,660
effective search space: 13381976280
effective search space used: 13381976280
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.