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Search of human proteins with 4507903
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507903 vaccinia related kinase 1 [Homo sapiens]
(396 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507903 vaccinia related kinase 1 [Homo sapiens] 811 0.0
gi|194440709 vaccinia related kinase 2 isoform 1 [Homo sapiens] 347 1e-95
gi|194440707 vaccinia related kinase 2 isoform 1 [Homo sapiens] 347 1e-95
gi|71164884 vaccinia related kinase 2 isoform 1 [Homo sapiens] 347 1e-95
gi|194440713 vaccinia related kinase 2 isoform 3 [Homo sapiens] 346 2e-95
gi|194440711 vaccinia related kinase 2 isoform 2 [Homo sapiens] 338 4e-93
gi|209862855 vaccinia related kinase 2 isoform 6 [Homo sapiens] 239 3e-63
gi|71164888 vaccinia related kinase 3 isoform 2 [Homo sapiens] 208 8e-54
gi|71164886 vaccinia related kinase 3 isoform 1 [Homo sapiens] 208 8e-54
gi|23199991 casein kinase 1 epsilon [Homo sapiens] 135 5e-32
gi|4503093 casein kinase 1 epsilon [Homo sapiens] 135 5e-32
gi|20544145 casein kinase 1, delta isoform 2 [Homo sapiens] 133 2e-31
gi|20149530 casein kinase 1, delta isoform 1 [Homo sapiens] 133 2e-31
gi|153791733 casein kinase 1, gamma 2 [Homo sapiens] 120 2e-27
gi|98986450 casein kinase 1, gamma 1 [Homo sapiens] 120 3e-27
gi|113462008 casein kinase 1, gamma 3 isoform 3 [Homo sapiens] 117 1e-26
gi|73532780 casein kinase 1, gamma 3 isoform 2 [Homo sapiens] 117 1e-26
gi|113462010 casein kinase 1, gamma 3 isoform 4 [Homo sapiens] 117 2e-26
gi|73532778 casein kinase 1, gamma 3 isoform 1 [Homo sapiens] 117 2e-26
gi|68303572 casein kinase 1, alpha 1 isoform 2 [Homo sapiens] 116 3e-26
gi|21624639 casein kinase 1, alpha 1-like [Homo sapiens] 111 1e-24
gi|68303575 casein kinase 1, alpha 1 isoform 1 [Homo sapiens] 108 1e-23
gi|116812624 tau tubulin kinase 2 [Homo sapiens] 103 2e-22
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 95 1e-19
gi|38327572 serine/threonine protein kinase 6 [Homo sapiens] 56 5e-08
gi|38327570 serine/threonine protein kinase 6 [Homo sapiens] 56 5e-08
gi|38327568 serine/threonine protein kinase 6 [Homo sapiens] 56 5e-08
gi|38327566 serine/threonine protein kinase 6 [Homo sapiens] 56 5e-08
gi|38327564 serine/threonine protein kinase 6 [Homo sapiens] 56 5e-08
gi|38327562 serine/threonine protein kinase 6 [Homo sapiens] 56 5e-08
>gi|4507903 vaccinia related kinase 1 [Homo sapiens]
Length = 396
Score = 811 bits (2095), Expect = 0.0
Identities = 396/396 (100%), Positives = 396/396 (100%)
Query: 1 MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSSE 60
MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSSE
Sbjct: 1 MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSSE 60
Query: 61 SVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHD 120
SVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHD
Sbjct: 61 SVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHD 120
Query: 121 KNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKA 180
KNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKA
Sbjct: 121 KNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKA 180
Query: 181 SNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSR 240
SNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSR
Sbjct: 181 SNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSR 240
Query: 241 RGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIA 300
RGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIA
Sbjct: 241 RGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIA 300
Query: 301 KYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRKK 360
KYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRKK
Sbjct: 301 KYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRKK 360
Query: 361 EIEESKEPGVEDTEWSNTQTEEAIQTRSRTRKRVQK 396
EIEESKEPGVEDTEWSNTQTEEAIQTRSRTRKRVQK
Sbjct: 361 EIEESKEPGVEDTEWSNTQTEEAIQTRSRTRKRVQK 396
>gi|194440709 vaccinia related kinase 2 isoform 1 [Homo sapiens]
Length = 508
Score = 347 bits (889), Expect = 1e-95
Identities = 190/401 (47%), Positives = 248/401 (61%), Gaps = 23/401 (5%)
Query: 16 KRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEPS 75
K L F G+++ DM +W +G IG GGFG IYLA + DA VVKVE
Sbjct: 8 KYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKPE--KDARHVVKVEYQ 65
Query: 76 DNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFG 135
+NGPLF+ELKFYQR AK + I+KWI ++L YLG+P ++GSGL + G+SYRFM+M+R G
Sbjct: 66 ENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLG 125
Query: 136 SDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYL 195
DLQKI N F + TVLQL +R+LD+LEYIHE+EYVHGDIKA+NLLL YKNPDQVYL
Sbjct: 126 IDLQKISGQNGT-FKKSTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGYKNPDQVYL 184
Query: 196 VDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWL 255
DYGL+YRYCP G HK+Y+E+P++ H+GTIEFTS+DAH GVA SRR D+EILGYCM++WL
Sbjct: 185 ADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWL 244
Query: 256 TGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKP 315
G LPWE NLKDP V+ +K + + + K P + EIA+++ L Y EKP
Sbjct: 245 CGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAYDEKP 304
Query: 316 LYENLRDILLQGLKAIGSKDDGKLDLSV---------VENGGLKAKTITKKRKKEIEES- 365
Y+ L+ IL +G D S+ V++ K + K + IE+
Sbjct: 305 NYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLIEKKV 364
Query: 366 -KEPGVEDTEWSNTQTE---------EAIQTRSRTRKRVQK 396
E E Q E EA Q +R R++ Q+
Sbjct: 365 HSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQE 405
>gi|194440707 vaccinia related kinase 2 isoform 1 [Homo sapiens]
Length = 508
Score = 347 bits (889), Expect = 1e-95
Identities = 190/401 (47%), Positives = 248/401 (61%), Gaps = 23/401 (5%)
Query: 16 KRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEPS 75
K L F G+++ DM +W +G IG GGFG IYLA + DA VVKVE
Sbjct: 8 KYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKPE--KDARHVVKVEYQ 65
Query: 76 DNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFG 135
+NGPLF+ELKFYQR AK + I+KWI ++L YLG+P ++GSGL + G+SYRFM+M+R G
Sbjct: 66 ENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLG 125
Query: 136 SDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYL 195
DLQKI N F + TVLQL +R+LD+LEYIHE+EYVHGDIKA+NLLL YKNPDQVYL
Sbjct: 126 IDLQKISGQNGT-FKKSTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGYKNPDQVYL 184
Query: 196 VDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWL 255
DYGL+YRYCP G HK+Y+E+P++ H+GTIEFTS+DAH GVA SRR D+EILGYCM++WL
Sbjct: 185 ADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWL 244
Query: 256 TGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKP 315
G LPWE NLKDP V+ +K + + + K P + EIA+++ L Y EKP
Sbjct: 245 CGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAYDEKP 304
Query: 316 LYENLRDILLQGLKAIGSKDDGKLDLSV---------VENGGLKAKTITKKRKKEIEES- 365
Y+ L+ IL +G D S+ V++ K + K + IE+
Sbjct: 305 NYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLIEKKV 364
Query: 366 -KEPGVEDTEWSNTQTE---------EAIQTRSRTRKRVQK 396
E E Q E EA Q +R R++ Q+
Sbjct: 365 HSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQE 405
>gi|71164884 vaccinia related kinase 2 isoform 1 [Homo sapiens]
Length = 508
Score = 347 bits (889), Expect = 1e-95
Identities = 190/401 (47%), Positives = 248/401 (61%), Gaps = 23/401 (5%)
Query: 16 KRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEPS 75
K L F G+++ DM +W +G IG GGFG IYLA + DA VVKVE
Sbjct: 8 KYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKPE--KDARHVVKVEYQ 65
Query: 76 DNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFG 135
+NGPLF+ELKFYQR AK + I+KWI ++L YLG+P ++GSGL + G+SYRFM+M+R G
Sbjct: 66 ENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLG 125
Query: 136 SDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYL 195
DLQKI N F + TVLQL +R+LD+LEYIHE+EYVHGDIKA+NLLL YKNPDQVYL
Sbjct: 126 IDLQKISGQNGT-FKKSTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGYKNPDQVYL 184
Query: 196 VDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWL 255
DYGL+YRYCP G HK+Y+E+P++ H+GTIEFTS+DAH GVA SRR D+EILGYCM++WL
Sbjct: 185 ADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWL 244
Query: 256 TGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKP 315
G LPWE NLKDP V+ +K + + + K P + EIA+++ L Y EKP
Sbjct: 245 CGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAYDEKP 304
Query: 316 LYENLRDILLQGLKAIGSKDDGKLDLSV---------VENGGLKAKTITKKRKKEIEES- 365
Y+ L+ IL +G D S+ V++ K + K + IE+
Sbjct: 305 NYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLIEKKV 364
Query: 366 -KEPGVEDTEWSNTQTE---------EAIQTRSRTRKRVQK 396
E E Q E EA Q +R R++ Q+
Sbjct: 365 HSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQE 405
>gi|194440713 vaccinia related kinase 2 isoform 3 [Homo sapiens]
Length = 396
Score = 346 bits (887), Expect = 2e-95
Identities = 172/309 (55%), Positives = 219/309 (70%), Gaps = 3/309 (0%)
Query: 16 KRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEPS 75
K L F G+++ DM +W +G IG GGFG IYLA + DA VVKVE
Sbjct: 8 KYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKPE--KDARHVVKVEYQ 65
Query: 76 DNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFG 135
+NGPLF+ELKFYQR AK + I+KWI ++L YLG+P ++GSGL + G+SYRFM+M+R G
Sbjct: 66 ENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLG 125
Query: 136 SDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYL 195
DLQKI N F + TVLQL +R+LD+LEYIHE+EYVHGDIKA+NLLL YKNPDQVYL
Sbjct: 126 IDLQKISGQNGT-FKKSTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGYKNPDQVYL 184
Query: 196 VDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWL 255
DYGL+YRYCP G HK+Y+E+P++ H+GTIEFTS+DAH GVA SRR D+EILGYCM++WL
Sbjct: 185 ADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWL 244
Query: 256 TGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKP 315
G LPWE NLKDP V+ +K + + + K P + EIA+++ L Y EKP
Sbjct: 245 CGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAYDEKP 304
Query: 316 LYENLRDIL 324
Y+ L+ IL
Sbjct: 305 NYQALKKIL 313
>gi|194440711 vaccinia related kinase 2 isoform 2 [Homo sapiens]
Length = 485
Score = 338 bits (868), Expect = 4e-93
Identities = 185/385 (48%), Positives = 240/385 (62%), Gaps = 23/385 (5%)
Query: 32 MAKKEWKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAA 91
M +W +G IG GGFG IYLA + DA VVKVE +NGPLF+ELKFYQR A
Sbjct: 1 MEGNQWVLGKKIGSGGFGLIYLAFPTNKPE--KDARHVVKVEYQENGPLFSELKFYQRVA 58
Query: 92 KPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSR 151
K + I+KWI ++L YLG+P ++GSGL + G+SYRFM+M+R G DLQKI N F +
Sbjct: 59 KKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQNGT-FKK 117
Query: 152 KTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHK 211
TVLQL +R+LD+LEYIHE+EYVHGDIKA+NLLL YKNPDQVYL DYGL+YRYCP G HK
Sbjct: 118 STVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGYKNPDQVYLADYGLSYRYCPNGNHK 177
Query: 212 EYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYV 271
+Y+E+P++ H+GTIEFTS+DAH GVA SRR D+EILGYCM++WL G LPWE NLKDP V
Sbjct: 178 QYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDPVAV 237
Query: 272 RDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAI 331
+ +K + + + K P + EIA+++ L Y EKP Y+ L+ IL +
Sbjct: 238 QTAKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKILNPHGIPL 297
Query: 332 GSKDDGKLDLSV---------VENGGLKAKTITKKRKKEIEES--KEPGVEDTEWSNTQT 380
G D S+ V++ K + K + IE+ E E Q
Sbjct: 298 GPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLIEKKVHSERSAESCATWKVQK 357
Query: 381 E---------EAIQTRSRTRKRVQK 396
E EA Q +R R++ Q+
Sbjct: 358 EEKLIGLMNNEAAQESTRRRQKYQE 382
>gi|209862855 vaccinia related kinase 2 isoform 6 [Homo sapiens]
Length = 390
Score = 239 bits (610), Expect = 3e-63
Identities = 133/288 (46%), Positives = 174/288 (60%), Gaps = 21/288 (7%)
Query: 129 MIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYK 188
M+M+R G DLQKI N F + TVLQL +R+LD+LEYIHE+EYVHGDIKA+NLLL YK
Sbjct: 1 MVMERLGIDLQKISGQNGT-FKKSTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGYK 59
Query: 189 NPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILG 248
NPDQVYL DYGL+YRYCP G HK+Y+E+P++ H+GTIEFTS+DAH GVA SRR D+EILG
Sbjct: 60 NPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILG 119
Query: 249 YCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKL 308
YCM++WL G LPWE NLKDP V+ +K + + + K P + EIA+++
Sbjct: 120 YCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHS 179
Query: 309 LDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSV---------VENGGLKAKTITKKRK 359
L Y EKP Y+ L+ IL +G D S+ V++ K + K
Sbjct: 180 LAYDEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHN 239
Query: 360 KEIEES--KEPGVEDTEWSNTQTE---------EAIQTRSRTRKRVQK 396
+ IE+ E E Q E EA Q +R R++ Q+
Sbjct: 240 RLIEKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQE 287
>gi|71164888 vaccinia related kinase 3 isoform 2 [Homo sapiens]
Length = 424
Score = 208 bits (529), Expect = 8e-54
Identities = 114/316 (36%), Positives = 173/316 (54%), Gaps = 11/316 (3%)
Query: 21 EQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSS---ESVGSDAPCVVKVEPSDN 77
E G ++TD + ++WK+ + G +Y A S+ +S +K++ D
Sbjct: 100 EALPTGTVLTDKSGRQWKLKSFQTRDNQGILYEAAPTSTLTCDSGPQKQKFSLKLDAKD- 158
Query: 78 GPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSD 137
G LF E F+QRAAKP Q+ KW + L +P G G+H YRF+++ G
Sbjct: 159 GRLFNEQNFFQRAAKPLQVNKWKKLYSTPLLAIPTCMGFGVHQDK---YRFLVLPSLGRS 215
Query: 138 LQKIYEANAKR-FSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLV 196
LQ + + K S ++VLQ++ R+LD LE++HE+EYVHG++ A N+ ++ ++ QV L
Sbjct: 216 LQSALDVSPKHVLSERSVLQVACRLLDALEFLHENEYVHGNVTAENIFVDPEDQSQVTLA 275
Query: 197 DYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLT 256
YG A+RYCP G H Y E + H+G +EF S+D H G PSRR DL+ LGYCM++WL
Sbjct: 276 GYGFAFRYCPSGKHVAYVEGSRSPHEGDLEFISMDLHKGCGPSRRSDLQSLGYCMLKWLY 335
Query: 257 GHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPL 316
G LPW + L + + + K ++ + + C + KY++ V L Y EKP
Sbjct: 336 GFLPWTNCLPNTEDIMKQKQKFVDKPGPFVGPCGHWIRPSETLQKYLKVVMALTYEEKPP 395
Query: 317 YENLR---DILLQGLK 329
Y LR + LLQ L+
Sbjct: 396 YAMLRNNLEALLQDLR 411
>gi|71164886 vaccinia related kinase 3 isoform 1 [Homo sapiens]
Length = 474
Score = 208 bits (529), Expect = 8e-54
Identities = 114/316 (36%), Positives = 173/316 (54%), Gaps = 11/316 (3%)
Query: 21 EQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSS---ESVGSDAPCVVKVEPSDN 77
E G ++TD + ++WK+ + G +Y A S+ +S +K++ D
Sbjct: 150 EALPTGTVLTDKSGRQWKLKSFQTRDNQGILYEAAPTSTLTCDSGPQKQKFSLKLDAKD- 208
Query: 78 GPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSD 137
G LF E F+QRAAKP Q+ KW + L +P G G+H YRF+++ G
Sbjct: 209 GRLFNEQNFFQRAAKPLQVNKWKKLYSTPLLAIPTCMGFGVHQDK---YRFLVLPSLGRS 265
Query: 138 LQKIYEANAKR-FSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLV 196
LQ + + K S ++VLQ++ R+LD LE++HE+EYVHG++ A N+ ++ ++ QV L
Sbjct: 266 LQSALDVSPKHVLSERSVLQVACRLLDALEFLHENEYVHGNVTAENIFVDPEDQSQVTLA 325
Query: 197 DYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLT 256
YG A+RYCP G H Y E + H+G +EF S+D H G PSRR DL+ LGYCM++WL
Sbjct: 326 GYGFAFRYCPSGKHVAYVEGSRSPHEGDLEFISMDLHKGCGPSRRSDLQSLGYCMLKWLY 385
Query: 257 GHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPL 316
G LPW + L + + + K ++ + + C + KY++ V L Y EKP
Sbjct: 386 GFLPWTNCLPNTEDIMKQKQKFVDKPGPFVGPCGHWIRPSETLQKYLKVVMALTYEEKPP 445
Query: 317 YENLR---DILLQGLK 329
Y LR + LLQ L+
Sbjct: 446 YAMLRNNLEALLQDLR 461
>gi|23199991 casein kinase 1 epsilon [Homo sapiens]
Length = 416
Score = 135 bits (341), Expect = 5e-32
Identities = 97/339 (28%), Positives = 156/339 (46%), Gaps = 33/339 (9%)
Query: 36 EWKVGLPIGQGGFGCIYL-ADMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPE 94
++++G IG G FG IYL A++ S E V CV P L E KFY+
Sbjct: 8 KYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQ----LHIESKFYK------ 57
Query: 95 QIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTV 154
+Q + +K+ G Y M+M+ G L+ ++ +++FS KTV
Sbjct: 58 MMQGGVGIPSIKWCGAEG------------DYNVMVMELLGPSLEDLFNFCSRKFSLKTV 105
Query: 155 LQLSLRILDILEYIHEHEYVHGDIKASNLLLNY-KNPDQVYLVDYGLAYRYCPEGVHKEY 213
L L+ +++ +EYIH ++H D+K N L+ K + VY++D+GLA +Y H+
Sbjct: 106 LLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHI 165
Query: 214 KEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWED---NLKDPKY 270
+ GT + SI+ H G+ SRR DLE LGY ++ + G LPW+ K KY
Sbjct: 166 PYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKY 225
Query: 271 VRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKA 330
R S+ + I L K P E + Y+ + L + +KP Y LR +
Sbjct: 226 ERISEKKMSTPIEVLC------KGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHR 279
Query: 331 IGSKDDGKLDLSVVENGGLKAKTITKKRKKEIEESKEPG 369
G D D ++++ G + + ++E E + G
Sbjct: 280 QGFSYDYVFDWNMLKFGAARNPEDVDRERREHEREERMG 318
>gi|4503093 casein kinase 1 epsilon [Homo sapiens]
Length = 416
Score = 135 bits (341), Expect = 5e-32
Identities = 97/339 (28%), Positives = 156/339 (46%), Gaps = 33/339 (9%)
Query: 36 EWKVGLPIGQGGFGCIYL-ADMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPE 94
++++G IG G FG IYL A++ S E V CV P L E KFY+
Sbjct: 8 KYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQ----LHIESKFYK------ 57
Query: 95 QIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTV 154
+Q + +K+ G Y M+M+ G L+ ++ +++FS KTV
Sbjct: 58 MMQGGVGIPSIKWCGAEG------------DYNVMVMELLGPSLEDLFNFCSRKFSLKTV 105
Query: 155 LQLSLRILDILEYIHEHEYVHGDIKASNLLLNY-KNPDQVYLVDYGLAYRYCPEGVHKEY 213
L L+ +++ +EYIH ++H D+K N L+ K + VY++D+GLA +Y H+
Sbjct: 106 LLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHI 165
Query: 214 KEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWED---NLKDPKY 270
+ GT + SI+ H G+ SRR DLE LGY ++ + G LPW+ K KY
Sbjct: 166 PYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKY 225
Query: 271 VRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKA 330
R S+ + I L K P E + Y+ + L + +KP Y LR +
Sbjct: 226 ERISEKKMSTPIEVLC------KGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHR 279
Query: 331 IGSKDDGKLDLSVVENGGLKAKTITKKRKKEIEESKEPG 369
G D D ++++ G + + ++E E + G
Sbjct: 280 QGFSYDYVFDWNMLKFGAARNPEDVDRERREHEREERMG 318
>gi|20544145 casein kinase 1, delta isoform 2 [Homo sapiens]
Length = 409
Score = 133 bits (335), Expect = 2e-31
Identities = 95/333 (28%), Positives = 154/333 (46%), Gaps = 33/333 (9%)
Query: 37 WKVGLPIGQGGFGCIYLA-DMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQ 95
+++G IG G FG IYL D+ + E V CV P L E K Y+
Sbjct: 9 YRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQ----LHIESKIYK------M 58
Query: 96 IQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVL 155
+Q + +++ G Y M+M+ G L+ ++ +++FS KTVL
Sbjct: 59 MQGGVGIPTIRWCGAEG------------DYNVMVMELLGPSLEDLFNFCSRKFSLKTVL 106
Query: 156 QLSLRILDILEYIHEHEYVHGDIKASNLLLNY-KNPDQVYLVDYGLAYRYCPEGVHKEYK 214
L+ +++ +EYIH ++H D+K N L+ K + VY++D+GLA +Y H+
Sbjct: 107 LLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIP 166
Query: 215 EDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWED---NLKDPKYV 271
+ GT + SI+ H G+ SRR DLE LGY ++ + G LPW+ K KY
Sbjct: 167 YRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYE 226
Query: 272 RDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAI 331
R S+ + I L K P E A Y+ + L + +KP Y LR +
Sbjct: 227 RISEKKMSTPIEVLC------KGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQ 280
Query: 332 GSKDDGKLDLSVVENGGLKAKTITKKRKKEIEE 364
G D D ++++ G +A ++ +++ EE
Sbjct: 281 GFSYDYVFDWNMLKFGASRAADDAERERRDREE 313
>gi|20149530 casein kinase 1, delta isoform 1 [Homo sapiens]
Length = 415
Score = 133 bits (335), Expect = 2e-31
Identities = 95/333 (28%), Positives = 154/333 (46%), Gaps = 33/333 (9%)
Query: 37 WKVGLPIGQGGFGCIYLA-DMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQ 95
+++G IG G FG IYL D+ + E V CV P L E K Y+
Sbjct: 9 YRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQ----LHIESKIYK------M 58
Query: 96 IQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVL 155
+Q + +++ G Y M+M+ G L+ ++ +++FS KTVL
Sbjct: 59 MQGGVGIPTIRWCGAEG------------DYNVMVMELLGPSLEDLFNFCSRKFSLKTVL 106
Query: 156 QLSLRILDILEYIHEHEYVHGDIKASNLLLNY-KNPDQVYLVDYGLAYRYCPEGVHKEYK 214
L+ +++ +EYIH ++H D+K N L+ K + VY++D+GLA +Y H+
Sbjct: 107 LLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIP 166
Query: 215 EDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWED---NLKDPKYV 271
+ GT + SI+ H G+ SRR DLE LGY ++ + G LPW+ K KY
Sbjct: 167 YRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYE 226
Query: 272 RDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAI 331
R S+ + I L K P E A Y+ + L + +KP Y LR +
Sbjct: 227 RISEKKMSTPIEVLC------KGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQ 280
Query: 332 GSKDDGKLDLSVVENGGLKAKTITKKRKKEIEE 364
G D D ++++ G +A ++ +++ EE
Sbjct: 281 GFSYDYVFDWNMLKFGASRAADDAERERRDREE 313
>gi|153791733 casein kinase 1, gamma 2 [Homo sapiens]
Length = 415
Score = 120 bits (302), Expect = 2e-27
Identities = 90/326 (27%), Positives = 150/326 (46%), Gaps = 36/326 (11%)
Query: 3 RVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSSESV 62
R+ A GR S R V M ++VG IG G FG ++ +++
Sbjct: 17 RMSKAGGGRSSHGIRSSGTSSGVL-----MVGPNFRVGKKIGCGNFG-----ELRLGKNL 66
Query: 63 GSDAPCVVKVEP--SDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHD 120
++ +K+EP S L E +FY++ + E GVP+ + G
Sbjct: 67 YTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATE--------------GVPQVYYFGPCG 112
Query: 121 KNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKA 180
K Y M+++ G L+ +++ + F+ KTVL ++++++ +EY+H ++ D+K
Sbjct: 113 K----YNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKP 168
Query: 181 SNLLLNY---KNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVA 237
N L+ K ++++D+GLA Y K + GT + SI+ H G
Sbjct: 169 ENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKE 228
Query: 238 PSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPG 297
SRR DLE LG+ + +L G LPW+ D R KI + + C +N P
Sbjct: 229 QSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLC---ENFPE 285
Query: 298 EIAKYMETVKLLDYTEKPLYENLRDI 323
E+A Y+ V+ LD+ EKP Y+ LR +
Sbjct: 286 EMATYLRYVRRLDFFEKPDYDYLRKL 311
>gi|98986450 casein kinase 1, gamma 1 [Homo sapiens]
Length = 422
Score = 120 bits (300), Expect = 3e-27
Identities = 83/297 (27%), Positives = 141/297 (47%), Gaps = 30/297 (10%)
Query: 32 MAKKEWKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEP--SDNGPLFTELKFYQR 89
M ++VG IG G FG ++ +++ ++ +K+EP S L E +FY++
Sbjct: 39 MVGPNFRVGKKIGCGNFG-----ELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQ 93
Query: 90 AAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRF 149
+ G+P+ + G K Y M+++ G L+ +++ + F
Sbjct: 94 LGSAGE-------------GLPQVYYFGPCGK----YNAMVLELLGPSLEDLFDLCDRTF 136
Query: 150 SRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNY---KNPDQVYLVDYGLAYRYCP 206
+ KTVL +++++L +EY+H ++ D+K N L+ K ++++D+GLA Y
Sbjct: 137 TLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYID 196
Query: 207 EGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLK 266
K + GT + SI+ H G SRR DLE LG+ + +L G LPW+
Sbjct: 197 PETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKA 256
Query: 267 DPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDI 323
D R KI + + C +N P E+A Y+ V+ LD+ EKP YE LR +
Sbjct: 257 DTLKERYQKIGDTKRNTPIEALC---ENFPEEMATYLRYVRRLDFFEKPDYEYLRTL 310
>gi|113462008 casein kinase 1, gamma 3 isoform 3 [Homo sapiens]
Length = 415
Score = 117 bits (294), Expect = 1e-26
Identities = 91/357 (25%), Positives = 161/357 (45%), Gaps = 42/357 (11%)
Query: 32 MAKKEWKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEP--SDNGPLFTELKFYQR 89
M ++VG IG G FG ++ +++ ++ +K+EP S L E +FY++
Sbjct: 38 MVGPNFRVGKKIGCGNFG-----ELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQ 92
Query: 90 AAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRF 149
+ G+P+ + G K Y M+++ G L+ +++ + F
Sbjct: 93 LGSGD--------------GIPQVYYFGPCGK----YNAMVLELLGPSLEDLFDLCDRTF 134
Query: 150 SRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNY---KNPDQVYLVDYGLAYRYCP 206
S KTVL ++++++ +EY+H ++ D+K N L+ K ++++D+GLA Y
Sbjct: 135 SLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYID 194
Query: 207 EGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLK 266
K + GT + SI+ H G SRR DLE LG+ + +L G LPW+
Sbjct: 195 PETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKA 254
Query: 267 DPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQ 326
D R KI + + C +N P E+A Y+ V+ LD+ EKP Y+ LR +
Sbjct: 255 DTLKERYQKIGDTKRATPIEVLC---ENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTD 310
Query: 327 GLKAIGSKDDGKLDL----------SVVENGGLKAKTITKKRKKEIEESKEPGVEDT 373
G D + D +V ++ L + + + ++++SK V T
Sbjct: 311 LFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSKNQVVSST 367
>gi|73532780 casein kinase 1, gamma 3 isoform 2 [Homo sapiens]
Length = 423
Score = 117 bits (294), Expect = 1e-26
Identities = 91/357 (25%), Positives = 161/357 (45%), Gaps = 42/357 (11%)
Query: 32 MAKKEWKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEP--SDNGPLFTELKFYQR 89
M ++VG IG G FG ++ +++ ++ +K+EP S L E +FY++
Sbjct: 38 MVGPNFRVGKKIGCGNFG-----ELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQ 92
Query: 90 AAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRF 149
+ G+P+ + G K Y M+++ G L+ +++ + F
Sbjct: 93 LGSGD--------------GIPQVYYFGPCGK----YNAMVLELLGPSLEDLFDLCDRTF 134
Query: 150 SRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNY---KNPDQVYLVDYGLAYRYCP 206
S KTVL ++++++ +EY+H ++ D+K N L+ K ++++D+GLA Y
Sbjct: 135 SLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYID 194
Query: 207 EGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLK 266
K + GT + SI+ H G SRR DLE LG+ + +L G LPW+
Sbjct: 195 PETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKA 254
Query: 267 DPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQ 326
D R KI + + C +N P E+A Y+ V+ LD+ EKP Y+ LR +
Sbjct: 255 DTLKERYQKIGDTKRATPIEVLC---ENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTD 310
Query: 327 GLKAIGSKDDGKLDL----------SVVENGGLKAKTITKKRKKEIEESKEPGVEDT 373
G D + D +V ++ L + + + ++++SK V T
Sbjct: 311 LFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSKNQVVSST 367
>gi|113462010 casein kinase 1, gamma 3 isoform 4 [Homo sapiens]
Length = 455
Score = 117 bits (292), Expect = 2e-26
Identities = 82/297 (27%), Positives = 141/297 (47%), Gaps = 32/297 (10%)
Query: 32 MAKKEWKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEP--SDNGPLFTELKFYQR 89
M ++VG IG G FG ++ +++ ++ +K+EP S L E +FY++
Sbjct: 38 MVGPNFRVGKKIGCGNFG-----ELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQ 92
Query: 90 AAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRF 149
+ G+P+ + G K Y M+++ G L+ +++ + F
Sbjct: 93 LGSGD--------------GIPQVYYFGPCGK----YNAMVLELLGPSLEDLFDLCDRTF 134
Query: 150 SRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNY---KNPDQVYLVDYGLAYRYCP 206
S KTVL ++++++ +EY+H ++ D+K N L+ K ++++D+GLA Y
Sbjct: 135 SLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYID 194
Query: 207 EGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLK 266
K + GT + SI+ H G SRR DLE LG+ + +L G LPW+
Sbjct: 195 PETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKA 254
Query: 267 DPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDI 323
D R KI + + C +N P E+A Y+ V+ LD+ EKP Y+ LR +
Sbjct: 255 DTLKERYQKIGDTKRATPIEVLC---ENFP-EMATYLRYVRRLDFFEKPDYDYLRKL 307
>gi|73532778 casein kinase 1, gamma 3 isoform 1 [Homo sapiens]
Length = 447
Score = 117 bits (292), Expect = 2e-26
Identities = 82/297 (27%), Positives = 141/297 (47%), Gaps = 32/297 (10%)
Query: 32 MAKKEWKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEP--SDNGPLFTELKFYQR 89
M ++VG IG G FG ++ +++ ++ +K+EP S L E +FY++
Sbjct: 38 MVGPNFRVGKKIGCGNFG-----ELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQ 92
Query: 90 AAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRF 149
+ G+P+ + G K Y M+++ G L+ +++ + F
Sbjct: 93 LGSGD--------------GIPQVYYFGPCGK----YNAMVLELLGPSLEDLFDLCDRTF 134
Query: 150 SRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNY---KNPDQVYLVDYGLAYRYCP 206
S KTVL ++++++ +EY+H ++ D+K N L+ K ++++D+GLA Y
Sbjct: 135 SLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYID 194
Query: 207 EGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLK 266
K + GT + SI+ H G SRR DLE LG+ + +L G LPW+
Sbjct: 195 PETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKA 254
Query: 267 DPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDI 323
D R KI + + C +N P E+A Y+ V+ LD+ EKP Y+ LR +
Sbjct: 255 DTLKERYQKIGDTKRATPIEVLC---ENFP-EMATYLRYVRRLDFFEKPDYDYLRKL 307
>gi|68303572 casein kinase 1, alpha 1 isoform 2 [Homo sapiens]
Length = 337
Score = 116 bits (291), Expect = 3e-26
Identities = 85/313 (27%), Positives = 152/313 (48%), Gaps = 29/313 (9%)
Query: 36 EWKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQ 95
++K+ IG G FG IYLA +N + G + ++ + + + L E K Y+
Sbjct: 16 KYKLVRKIGSGSFGDIYLA-INITN--GEEVAVKLESQKARHPQLLYESKLYKI------ 66
Query: 96 IQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVL 155
+Q + +++ G K Y ++MD G L+ ++ ++RF+ KTVL
Sbjct: 67 LQGGVGIPHIRWYG------------QEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVL 114
Query: 156 QLSLRILDILEYIHEHEYVHGDIKASNLLLNY-KNPDQVYLVDYGLAYRYCPEGV--HKE 212
L+ +++ +EY+H ++H DIK N L+ ++ ++++L+D+GLA +Y H
Sbjct: 115 MLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIP 174
Query: 213 YKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVR 272
Y+ED GT + SI+AH G+ SRR D+E LGY ++ + LPW+ K +
Sbjct: 175 YREDKNL--TGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQK 232
Query: 273 DSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAIG 332
KI ++ + C K P E A Y+ + L + E P Y LR + + +
Sbjct: 233 YEKISEKKMSTPVEVLC---KGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLN 289
Query: 333 SKDDGKLDLSVVE 345
+ D D ++++
Sbjct: 290 HQYDYTFDWTMLK 302
>gi|21624639 casein kinase 1, alpha 1-like [Homo sapiens]
Length = 337
Score = 111 bits (277), Expect = 1e-24
Identities = 90/351 (25%), Positives = 160/351 (45%), Gaps = 41/351 (11%)
Query: 36 EWKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQ 95
++K+ IG G FG +YL ++ G + ++ + + L E K Y
Sbjct: 16 KYKLVRKIGSGSFGDVYLGITTTN---GEEVAVKLESQKVKHPQLLYESKLY-------- 64
Query: 96 IQKWIRTRKLKYLGVPK-YWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTV 154
T +G+P +W D N ++MD G L+ ++ ++RF+ KTV
Sbjct: 65 ------TILQGGVGIPHMHWYGQEKDNN-----VLVMDLLGPSLEDLFNFCSRRFTMKTV 113
Query: 155 LQLSLRILDILEYIHEHEYVHGDIKASNLLLNY-KNPDQVYLVDYGLAYRYCPEGV--HK 211
L L+ +++ +EY+H ++H DIK N L+ ++ ++++L+D+GLA +Y H
Sbjct: 114 LMLADQMISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHI 173
Query: 212 EYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYV 271
Y+ED GT+ + SI+AH G+ SRR D+E LGY + + LPW+ K
Sbjct: 174 PYREDKHLI--GTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQ 231
Query: 272 RDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAI 331
+ KI ++ + C K P E A Y+ + L + E P Y LR + + +
Sbjct: 232 KYEKISEKKMSTPVEVLC---KGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTL 288
Query: 332 GSKDDGKLDLSVVENGGLKAKTITKKRKKEIEESKEPGVEDTEWSNTQTEE 382
+ D D ++++ +K ++ S G + + QTE+
Sbjct: 289 NHQYDYTFDWTMLK----------QKAAQQAASSSGQGQQAQTQTGKQTEK 329
>gi|68303575 casein kinase 1, alpha 1 isoform 1 [Homo sapiens]
Length = 365
Score = 108 bits (269), Expect = 1e-23
Identities = 86/341 (25%), Positives = 152/341 (44%), Gaps = 57/341 (16%)
Query: 36 EWKVGLPIGQGGFGCIYLADMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQ 95
++K+ IG G FG IYLA +N + G + ++ + + + L E K Y+
Sbjct: 16 KYKLVRKIGSGSFGDIYLA-INITN--GEEVAVKLESQKARHPQLLYESKLYKI------ 66
Query: 96 IQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVL 155
+Q + +++ G K Y ++MD G L+ ++ ++RF+ KTVL
Sbjct: 67 LQGGVGIPHIRWYG------------QEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVL 114
Query: 156 QLSLRILDILEYIHEHEYVHGDIKASNLLL-----------------------------N 186
L+ +++ +EY+H ++H DIK N L+ +
Sbjct: 115 MLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKCLESPVGKRKRSMTVSTSQDPS 174
Query: 187 YKNPDQVYLVDYGLAYRYCPEGV--HKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDL 244
+ +Q++L+D+GLA +Y H Y+ED GT + SI+AH G+ SRR D+
Sbjct: 175 FSGLNQLFLIDFGLAKKYRDNRTRQHIPYREDKNLT--GTARYASINAHLGIEQSRRDDM 232
Query: 245 EILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYME 304
E LGY ++ + LPW+ K + KI ++ + C K P E A Y+
Sbjct: 233 ESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLC---KGFPAEFAMYLN 289
Query: 305 TVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVE 345
+ L + E P Y LR + + + + D D ++++
Sbjct: 290 YCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLK 330
>gi|116812624 tau tubulin kinase 2 [Homo sapiens]
Length = 1244
Score = 103 bits (258), Expect = 2e-22
Identities = 94/334 (28%), Positives = 150/334 (44%), Gaps = 48/334 (14%)
Query: 32 MAKKEWKVGLPIGQGGFGCIYLA-DMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRA 90
+ K+ WKV IG GGFG IY A DM + E+V +KVE A
Sbjct: 16 LVKERWKVLRKIGGGGFGEIYDALDMLTRENVA------LKVES---------------A 54
Query: 91 AKPEQIQKWIRTRKLKYLG---VPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAK 147
+P+Q+ K K G V ++ G G +D+ + +++M G +L + + ++
Sbjct: 55 QQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDR----FNYVVMQLQGRNLADLRRSQSR 110
Query: 148 -RFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNY--KNPDQVYLVDYGLAYRY 204
F+ T L+L +IL+ +E IH ++H DIK SN + + Y++D+GLA ++
Sbjct: 111 GTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQF 170
Query: 205 CPEGVHKEYKEDPKRC---HDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPW 261
+ P R GT+ + SI+AH R DL L Y +++++ G LPW
Sbjct: 171 ----TNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPW 226
Query: 262 EDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLR 321
+KD + V K RY D K+ P E + +++ + LDY KP Y+ L
Sbjct: 227 R-KIKDKEQVGSIKERY--------DHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLT 277
Query: 322 DILLQGLKAIGSKDDGKLDLSVVENGGLKAKTIT 355
+ +K G + D N G T T
Sbjct: 278 SVFDNSIKTFGVIESDPFDWEKTGNDGSLTTTTT 311
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 94.7 bits (234), Expect = 1e-19
Identities = 86/319 (26%), Positives = 143/319 (44%), Gaps = 48/319 (15%)
Query: 32 MAKKEWKVGLPIGQGGFGCIYLA-DMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRA 90
+ K WKV IG GGFG IY A D+ + E+V +KVE A
Sbjct: 29 VVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVA------LKVES---------------A 67
Query: 91 AKPEQIQKWIRTRKLKYLG---VPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAK 147
+P+Q+ K K G V ++ G G ++K + +++M G +L + + +
Sbjct: 68 QQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEK----FNYVVMQLQGRNLADLRRSQPR 123
Query: 148 -RFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNY--KNPDQVYLVDYGLAYRY 204
F+ T L+L +IL+ +E IH ++H DIK SN + + Y++D+GLA +Y
Sbjct: 124 GTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQY 183
Query: 205 CPEGVHKEYKEDPKRC---HDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPW 261
+ P R GT+ + S++AH R DL L Y ++++ G LPW
Sbjct: 184 ----TNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPW 239
Query: 262 EDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLR 321
+KD + V K +Y + K+ P E +++ + LDY KP Y+ +
Sbjct: 240 R-KIKDKEQVGMIKEKYEHRMLL--------KHMPSEFHLFLDHIASLDYFTKPDYQLIM 290
Query: 322 DILLQGLKAIGSKDDGKLD 340
+ +K G ++ D
Sbjct: 291 SVFENSMKERGIAENEAFD 309
>gi|38327572 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 56.2 bits (134), Expect = 5e-08
Identities = 62/275 (22%), Positives = 117/275 (42%), Gaps = 41/275 (14%)
Query: 13 SSAKRHLAEQFAVGEIITDMAKKEW-----KVGLPIGQGGFGCIYLADMNSSESVGSDAP 67
S+ + + E+ A + + K++W ++G P+G+G FG +YLA S+ +
Sbjct: 104 SAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFI----- 158
Query: 68 CVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRK-LKYLGVPKYWGSGLHDKNGKSY 126
+KV LF ++A Q+++ + + L++ + + +G HD + Y
Sbjct: 159 LALKV-------LFKAQ--LEKAGVEHQLRREVEIQSHLRHPNILRLYGY-FHDAT-RVY 207
Query: 127 RFMIMDRFGS---DLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNL 183
+ G+ +LQK+ +F + + + L Y H +H DIK NL
Sbjct: 208 LILEYAPLGTVYRELQKL-----SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENL 262
Query: 184 LLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGD 243
LL + ++ + D+G + VH C GT+++ + G + D
Sbjct: 263 LLG--SAGELKIADFGWS-------VHAPSSRRTTLC--GTLDYLPPEMIEGRMHDEKVD 311
Query: 244 LEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRY 278
L LG ++L G P+E N Y R S++ +
Sbjct: 312 LWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEF 346
>gi|38327570 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 56.2 bits (134), Expect = 5e-08
Identities = 62/275 (22%), Positives = 117/275 (42%), Gaps = 41/275 (14%)
Query: 13 SSAKRHLAEQFAVGEIITDMAKKEW-----KVGLPIGQGGFGCIYLADMNSSESVGSDAP 67
S+ + + E+ A + + K++W ++G P+G+G FG +YLA S+ +
Sbjct: 104 SAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFI----- 158
Query: 68 CVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRK-LKYLGVPKYWGSGLHDKNGKSY 126
+KV LF ++A Q+++ + + L++ + + +G HD + Y
Sbjct: 159 LALKV-------LFKAQ--LEKAGVEHQLRREVEIQSHLRHPNILRLYGY-FHDAT-RVY 207
Query: 127 RFMIMDRFGS---DLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNL 183
+ G+ +LQK+ +F + + + L Y H +H DIK NL
Sbjct: 208 LILEYAPLGTVYRELQKL-----SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENL 262
Query: 184 LLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGD 243
LL + ++ + D+G + VH C GT+++ + G + D
Sbjct: 263 LLG--SAGELKIADFGWS-------VHAPSSRRTTLC--GTLDYLPPEMIEGRMHDEKVD 311
Query: 244 LEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRY 278
L LG ++L G P+E N Y R S++ +
Sbjct: 312 LWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEF 346
>gi|38327568 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 56.2 bits (134), Expect = 5e-08
Identities = 62/275 (22%), Positives = 117/275 (42%), Gaps = 41/275 (14%)
Query: 13 SSAKRHLAEQFAVGEIITDMAKKEW-----KVGLPIGQGGFGCIYLADMNSSESVGSDAP 67
S+ + + E+ A + + K++W ++G P+G+G FG +YLA S+ +
Sbjct: 104 SAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFI----- 158
Query: 68 CVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRK-LKYLGVPKYWGSGLHDKNGKSY 126
+KV LF ++A Q+++ + + L++ + + +G HD + Y
Sbjct: 159 LALKV-------LFKAQ--LEKAGVEHQLRREVEIQSHLRHPNILRLYGY-FHDAT-RVY 207
Query: 127 RFMIMDRFGS---DLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNL 183
+ G+ +LQK+ +F + + + L Y H +H DIK NL
Sbjct: 208 LILEYAPLGTVYRELQKL-----SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENL 262
Query: 184 LLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGD 243
LL + ++ + D+G + VH C GT+++ + G + D
Sbjct: 263 LLG--SAGELKIADFGWS-------VHAPSSRRTTLC--GTLDYLPPEMIEGRMHDEKVD 311
Query: 244 LEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRY 278
L LG ++L G P+E N Y R S++ +
Sbjct: 312 LWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEF 346
>gi|38327566 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 56.2 bits (134), Expect = 5e-08
Identities = 62/275 (22%), Positives = 117/275 (42%), Gaps = 41/275 (14%)
Query: 13 SSAKRHLAEQFAVGEIITDMAKKEW-----KVGLPIGQGGFGCIYLADMNSSESVGSDAP 67
S+ + + E+ A + + K++W ++G P+G+G FG +YLA S+ +
Sbjct: 104 SAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFI----- 158
Query: 68 CVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRK-LKYLGVPKYWGSGLHDKNGKSY 126
+KV LF ++A Q+++ + + L++ + + +G HD + Y
Sbjct: 159 LALKV-------LFKAQ--LEKAGVEHQLRREVEIQSHLRHPNILRLYGY-FHDAT-RVY 207
Query: 127 RFMIMDRFGS---DLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNL 183
+ G+ +LQK+ +F + + + L Y H +H DIK NL
Sbjct: 208 LILEYAPLGTVYRELQKL-----SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENL 262
Query: 184 LLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGD 243
LL + ++ + D+G + VH C GT+++ + G + D
Sbjct: 263 LLG--SAGELKIADFGWS-------VHAPSSRRTTLC--GTLDYLPPEMIEGRMHDEKVD 311
Query: 244 LEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRY 278
L LG ++L G P+E N Y R S++ +
Sbjct: 312 LWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEF 346
>gi|38327564 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 56.2 bits (134), Expect = 5e-08
Identities = 62/275 (22%), Positives = 117/275 (42%), Gaps = 41/275 (14%)
Query: 13 SSAKRHLAEQFAVGEIITDMAKKEW-----KVGLPIGQGGFGCIYLADMNSSESVGSDAP 67
S+ + + E+ A + + K++W ++G P+G+G FG +YLA S+ +
Sbjct: 104 SAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFI----- 158
Query: 68 CVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRK-LKYLGVPKYWGSGLHDKNGKSY 126
+KV LF ++A Q+++ + + L++ + + +G HD + Y
Sbjct: 159 LALKV-------LFKAQ--LEKAGVEHQLRREVEIQSHLRHPNILRLYGY-FHDAT-RVY 207
Query: 127 RFMIMDRFGS---DLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNL 183
+ G+ +LQK+ +F + + + L Y H +H DIK NL
Sbjct: 208 LILEYAPLGTVYRELQKL-----SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENL 262
Query: 184 LLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGD 243
LL + ++ + D+G + VH C GT+++ + G + D
Sbjct: 263 LLG--SAGELKIADFGWS-------VHAPSSRRTTLC--GTLDYLPPEMIEGRMHDEKVD 311
Query: 244 LEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRY 278
L LG ++L G P+E N Y R S++ +
Sbjct: 312 LWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEF 346
>gi|38327562 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 56.2 bits (134), Expect = 5e-08
Identities = 62/275 (22%), Positives = 117/275 (42%), Gaps = 41/275 (14%)
Query: 13 SSAKRHLAEQFAVGEIITDMAKKEW-----KVGLPIGQGGFGCIYLADMNSSESVGSDAP 67
S+ + + E+ A + + K++W ++G P+G+G FG +YLA S+ +
Sbjct: 104 SAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFI----- 158
Query: 68 CVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRK-LKYLGVPKYWGSGLHDKNGKSY 126
+KV LF ++A Q+++ + + L++ + + +G HD + Y
Sbjct: 159 LALKV-------LFKAQ--LEKAGVEHQLRREVEIQSHLRHPNILRLYGY-FHDAT-RVY 207
Query: 127 RFMIMDRFGS---DLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNL 183
+ G+ +LQK+ +F + + + L Y H +H DIK NL
Sbjct: 208 LILEYAPLGTVYRELQKL-----SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENL 262
Query: 184 LLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGD 243
LL + ++ + D+G + VH C GT+++ + G + D
Sbjct: 263 LLG--SAGELKIADFGWS-------VHAPSSRRTTLC--GTLDYLPPEMIEGRMHDEKVD 311
Query: 244 LEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRY 278
L LG ++L G P+E N Y R S++ +
Sbjct: 312 LWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEF 346
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.135 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,077,215
Number of Sequences: 37866
Number of extensions: 693447
Number of successful extensions: 2890
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 319
Number of HSP's successfully gapped in prelim test: 266
Number of HSP's that attempted gapping in prelim test: 2302
Number of HSP's gapped (non-prelim): 712
length of query: 396
length of database: 18,247,518
effective HSP length: 104
effective length of query: 292
effective length of database: 14,309,454
effective search space: 4178360568
effective search space used: 4178360568
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.