Guide to the Human Genome
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Name: NKX2-1 Sequence: fasta or formatted (371aa) NCBI GI: 4507715
Description:

thyroid transcription factor 1 isoform 2

Referenced in:

Homeobox and Related Proteins
Lung
Thyroid and Thyroid Hormone Receptor

Other entries for this name:
alt prot [401aa] thyroid transcription factor 1 isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            13.7         51           5
 C cysteine            1.1          4           1
 D aspartate           2.4          9           1
 E glutamate           2.2          8           2
 F phenylalanine       1.6          6           1
 G glycine            12.9         48           8
 H histidine           4.3         16           2
 I isoleucine          1.3          5           1
 K lysine              3.8         14           2
 L leucine             6.7         25           2
 M methionine          4.0         15           1
 N asparagine          2.4          9           1
 P proline             7.8         29           2
 Q glutamine          10.2         38           4
 R arginine            4.3         16           2
 S serine              9.7         36           2
 T threonine           3.2         12           2
 V valine              4.3         16           1
 W tryptophan          0.8          3           1
 Y tyrosine            3.0         11           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   thyroid transcription factor 1 isoform 2 
NKX2-1                1.000   thyroid transcription factor 1 isoform 1 
NKX2-4                0.453   NK2 homeobox 4 
NKX2-3                0.162   NK2 transcription factor related, locus 3 
NKX2-2                0.153   NK2 transcription factor related, locus 2 
NKX2-6                0.149   NK2 transcription factor related, locus 6 
NKX2-5                0.143   NK2 transcription factor related, locus 5 
NKX2-8                0.139   NK2 homeobox 8 
NKX3-2                0.090   NK3 homeobox 2 
NKX3-1                0.083   NK3 homeobox 1 
MNX1                  0.080   homeo box HB9 
PHOX2B                0.072   paired-like homeobox 2b 
HLX                   0.071   H2.0-like homeobox 
LBX1                  0.071   ladybird homeobox 1 
TLX2                  0.071   T-cell leukemia homeobox 2 
NKX1-2                0.068   NK1 homeobox 2 
NKX1-2                0.068   PREDICTED: NK1 homeobox 2 
NKX1-2                0.068   PREDICTED: NK1 homeobox 2 
NKX1-2                0.068   PREDICTED: NK1 homeobox 2 
HMX1                  0.068   homeo box (H6 family) 1 
HMX3                  0.068   H6 family homeobox 3 
HOXB3                 0.067   homeobox B3 
NKX1-1                0.067   PREDICTED: NK1 homeobox 1 
NKX1-1                0.067   PREDICTED: NK1 homeobox 1 
NKX1-1                0.067   PREDICTED: HPX-153 homeobox 
BSX                   0.065   brain specific homeobox 
HMX2                  0.064   H6 family homeobox 2 
PDX1                  0.063   pancreatic and duodenal homeobox 1 
DLX1                  0.063   distal-less homeobox 1 isoform 1 
HOXD3                 0.061   homeobox D3 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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