BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens] (292 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens] 587 e-168 gi|27262638 sperm associated antigen 1 [Homo sapiens] 89 3e-18 gi|27262636 sperm associated antigen 1 [Homo sapiens] 89 3e-18 gi|21361356 translocase of outer mitochondrial membrane 34 [Homo... 84 1e-16 gi|54607135 translocase of outer mitochondrial membrane 70 homol... 82 6e-16 gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens] 78 8e-15 gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens] 78 8e-15 gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens] 78 8e-15 gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 77 2e-14 gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 77 2e-14 gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 75 5e-14 gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 75 5e-14 gi|89179321 smooth muscle cell associated protein-1 isoform 3 [H... 75 7e-14 gi|29725607 smooth muscle cell associated protein-1 isoform 2 [H... 75 7e-14 gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 71 1e-12 gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 70 3e-12 gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 67 2e-11 gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 65 5e-11 gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 64 1e-10 gi|156627581 tetratricopeptide repeat domain 4 [Homo sapiens] 62 8e-10 gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap... 61 1e-09 gi|17149853 WAF-1/CIP1 stabilizing protein 39 [Homo sapiens] 58 1e-08 gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] 57 1e-08 gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] 57 1e-08 gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] 57 1e-08 gi|19923193 heat shock 70kD protein binding protein [Homo sapiens] 57 3e-08 gi|4503729 FK506 binding protein 52 [Homo sapiens] 55 7e-08 gi|52630440 FK506-binding protein 8 [Homo sapiens] 55 1e-07 gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens] 54 2e-07 gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 52 5e-07 >gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens] Length = 292 Score = 587 bits (1514), Expect = e-168 Identities = 292/292 (100%), Positives = 292/292 (100%) Query: 1 MGEKSENCGVPEDLLNGLKVTDTQEAECAGPPVPDPKNQHSQSKLLRDDEAHLQEDQGEE 60 MGEKSENCGVPEDLLNGLKVTDTQEAECAGPPVPDPKNQHSQSKLLRDDEAHLQEDQGEE Sbjct: 1 MGEKSENCGVPEDLLNGLKVTDTQEAECAGPPVPDPKNQHSQSKLLRDDEAHLQEDQGEE 60 Query: 61 ECFHDCSASFEEEPGADKVENKSNEDVNSSELDEEYLIELEKNMSDEEKQKRREESTRLK 120 ECFHDCSASFEEEPGADKVENKSNEDVNSSELDEEYLIELEKNMSDEEKQKRREESTRLK Sbjct: 61 ECFHDCSASFEEEPGADKVENKSNEDVNSSELDEEYLIELEKNMSDEEKQKRREESTRLK 120 Query: 121 EEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSK 180 EEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSK Sbjct: 121 EEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSK 180 Query: 181 AIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQIEERN 240 AIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQIEERN Sbjct: 181 AIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQIEERN 240 Query: 241 ERLKEEMLGKLKDLGNLVLRPFGLSTENFQIKQDSSTGSYSINFVQNPNNNR 292 ERLKEEMLGKLKDLGNLVLRPFGLSTENFQIKQDSSTGSYSINFVQNPNNNR Sbjct: 241 ERLKEEMLGKLKDLGNLVLRPFGLSTENFQIKQDSSTGSYSINFVQNPNNNR 292 >gi|27262638 sperm associated antigen 1 [Homo sapiens] Length = 926 Score = 89.4 bits (220), Expect = 3e-18 Identities = 55/212 (25%), Positives = 97/212 (45%), Gaps = 24/212 (11%) Query: 57 QGEEECFHDCSASFEEEPGADKVEN---------------KSNEDVNSSE-LDEEYLIEL 100 +G C H + + P K K +ED +D+ +L ++ Sbjct: 132 RGSNSCLHVGKEKYSKRPTKKKTPRDYAEWDKFDVEKECLKIDEDYKEKTVIDKSHLSKI 191 Query: 101 EKNMSDEEKQKRREE--STRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILF 158 E + ++ ++ +TR KE+GNE F GDY EA Y+R++ P+ + + Sbjct: 192 ETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISALPTV------VAY 245 Query: 159 SNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEK 218 +NRA A +K A DC K ++L P ++A+LRRA Y+ +KL EA ED +L+ Sbjct: 246 NNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDV 305 Query: 219 DPSIHQAREACMRLPKQIEERNERLKEEMLGK 250 +P A++ + + ++ + + GK Sbjct: 306 EPDNDLAKKTLSEVERDLKNSEAASETQTKGK 337 Score = 84.3 bits (207), Expect = 1e-16 Identities = 47/128 (36%), Positives = 73/128 (57%), Gaps = 3/128 (2%) Query: 114 EESTRLKEEGNEQFKKGDYIEAESSYSRA---LEMCPSCFQKERSILFSNRAAARMKQDK 170 E LK +GNE F+ G + EA YS A LE S + SIL+SNRAA +K+ Sbjct: 443 ENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACYLKEGN 502 Query: 171 KEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACM 230 I DC++A++L+P ++ +LRRA YE ++ +A DYK++L+ D + A ++ Sbjct: 503 CSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGLQLANDSVN 562 Query: 231 RLPKQIEE 238 RL + + E Sbjct: 563 RLSRILME 570 Score = 58.2 bits (139), Expect = 9e-09 Identities = 39/135 (28%), Positives = 68/135 (50%), Gaps = 7/135 (5%) Query: 94 EEYLIELEKNMSDEEKQKRREEST--RLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQ 151 +E + + + S +Q +E T LKEEGN+ +Y +A S YS L++ Sbjct: 599 KEMISKQAGDSSSHRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECLKI-----N 653 Query: 152 KERSILFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALED 211 + +++NRA +K + E A DC +A+QL ++A RRA ++ ++L D Sbjct: 654 NKECAIYTNRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLID 713 Query: 212 YKSILEKDPSIHQAR 226 ++ DPSI +A+ Sbjct: 714 LNKVILLDPSIIEAK 728 >gi|27262636 sperm associated antigen 1 [Homo sapiens] Length = 926 Score = 89.4 bits (220), Expect = 3e-18 Identities = 55/212 (25%), Positives = 97/212 (45%), Gaps = 24/212 (11%) Query: 57 QGEEECFHDCSASFEEEPGADKVEN---------------KSNEDVNSSE-LDEEYLIEL 100 +G C H + + P K K +ED +D+ +L ++ Sbjct: 132 RGSNSCLHVGKEKYSKRPTKKKTPRDYAEWDKFDVEKECLKIDEDYKEKTVIDKSHLSKI 191 Query: 101 EKNMSDEEKQKRREE--STRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILF 158 E + ++ ++ +TR KE+GNE F GDY EA Y+R++ P+ + + Sbjct: 192 ETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISALPTV------VAY 245 Query: 159 SNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEK 218 +NRA A +K A DC K ++L P ++A+LRRA Y+ +KL EA ED +L+ Sbjct: 246 NNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDV 305 Query: 219 DPSIHQAREACMRLPKQIEERNERLKEEMLGK 250 +P A++ + + ++ + + GK Sbjct: 306 EPDNDLAKKTLSEVERDLKNSEAASETQTKGK 337 Score = 84.3 bits (207), Expect = 1e-16 Identities = 47/128 (36%), Positives = 73/128 (57%), Gaps = 3/128 (2%) Query: 114 EESTRLKEEGNEQFKKGDYIEAESSYSRA---LEMCPSCFQKERSILFSNRAAARMKQDK 170 E LK +GNE F+ G + EA YS A LE S + SIL+SNRAA +K+ Sbjct: 443 ENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACYLKEGN 502 Query: 171 KEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACM 230 I DC++A++L+P ++ +LRRA YE ++ +A DYK++L+ D + A ++ Sbjct: 503 CSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGLQLANDSVN 562 Query: 231 RLPKQIEE 238 RL + + E Sbjct: 563 RLSRILME 570 Score = 58.2 bits (139), Expect = 9e-09 Identities = 39/135 (28%), Positives = 68/135 (50%), Gaps = 7/135 (5%) Query: 94 EEYLIELEKNMSDEEKQKRREEST--RLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQ 151 +E + + + S +Q +E T LKEEGN+ +Y +A S YS L++ Sbjct: 599 KEMISKQAGDSSSHRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECLKI-----N 653 Query: 152 KERSILFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALED 211 + +++NRA +K + E A DC +A+QL ++A RRA ++ ++L D Sbjct: 654 NKECAIYTNRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLID 713 Query: 212 YKSILEKDPSIHQAR 226 ++ DPSI +A+ Sbjct: 714 LNKVILLDPSIIEAK 728 >gi|21361356 translocase of outer mitochondrial membrane 34 [Homo sapiens] Length = 309 Score = 84.3 bits (207), Expect = 1e-16 Identities = 46/121 (38%), Positives = 67/121 (55%), Gaps = 3/121 (2%) Query: 119 LKEEGNEQFKKGDYIEAESSYSRALEMCP---SCFQKERSILFSNRAAARMKQDKKEMAI 175 L+ GNE F+ G Y EA + Y RAL + S +E S+L+SNRAA +K I Sbjct: 12 LRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCI 71 Query: 176 NDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQ 235 DC+ A+ L P I+ +LRRA YE +K A DYK++L+ D ++ A E R+ + Sbjct: 72 KDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRA 131 Query: 236 I 236 + Sbjct: 132 L 132 Score = 58.2 bits (139), Expect = 9e-09 Identities = 33/107 (30%), Positives = 60/107 (56%), Gaps = 5/107 (4%) Query: 114 EESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEM 173 E++ LKEEGNE KKG++ +A YS +L +C + S +SNRA + + Sbjct: 191 EKARVLKEEGNELVKKGNHKKAIEKYSESL-LCSNL----ESATYSNRALCYLVLKQYTE 245 Query: 174 AINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDP 220 A+ DC++A++L+ ++A RRA+ ++ + D ++L+ +P Sbjct: 246 AVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEP 292 >gi|54607135 translocase of outer mitochondrial membrane 70 homolog A [Homo sapiens] Length = 608 Score = 82.0 bits (201), Expect = 6e-16 Identities = 38/96 (39%), Positives = 59/96 (61%) Query: 120 KEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCS 179 K +GN+ FK G Y +A Y+ A+ +CP+ + S + NRAAA + K + DC+ Sbjct: 118 KNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCT 177 Query: 180 KAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSI 215 KA++LNP Y++A+ RRA+ +EK D E LED ++ Sbjct: 178 KAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAV 213 >gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens] Length = 705 Score = 78.2 bits (191), Expect = 8e-15 Identities = 64/218 (29%), Positives = 101/218 (46%), Gaps = 24/218 (11%) Query: 12 EDLLNGLKVTDT-----QEAECAGPPVPDPKNQHSQSKLLRDDEAHLQEDQGEEECFHDC 66 +DL LK D QE P V ++ +LL ++EDQ E+EC Sbjct: 7 KDLQKFLKNVDEISNLIQEMNSDDPVVQQKAVLETEKRLLL-----MEEDQEEDECRTTL 61 Query: 67 SASFEEEPGADKVENKSNEDVNSSELDEEYLIELEKNMSDEEKQKRREE--STRLKEEGN 124 + + P + KS E++NS E +L +EK+ + K++R + + LKE+GN Sbjct: 62 NKTMISPP---QTAMKSAEEINS----EAFLASVEKDAKERAKRRRENKVLADALKEKGN 114 Query: 125 EQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSKAIQL 184 E F +G+Y A YS LE K+ +L++NRA A MK + E A+ DC A++ Sbjct: 115 EAFAEGNYETAILRYSEGLEKL-----KDMKVLYTNRAQAYMKLEDYEKALVDCEWALKC 169 Query: 185 NPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSI 222 + +A + + E YK ILE +P + Sbjct: 170 DEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKL 207 >gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens] Length = 929 Score = 78.2 bits (191), Expect = 8e-15 Identities = 46/128 (35%), Positives = 73/128 (57%), Gaps = 8/128 (6%) Query: 115 ESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSIL---FSNRAAARMKQDKK 171 E+ +LKEEGN F+ DY A +SYS+AL++ K++++L + NRAA +K + Sbjct: 5 EAVQLKEEGNRHFQLQDYKAATNSYSQALKLT-----KDKALLATLYRNRAACGLKTESY 59 Query: 172 EMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMR 231 A +D S+AI +N S I+A+ RR + E KLD+A +D + +P +E R Sbjct: 60 VQAASDASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRR 119 Query: 232 LPKQIEER 239 L I+E+ Sbjct: 120 LNTSIQEK 127 >gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens] Length = 931 Score = 78.2 bits (191), Expect = 8e-15 Identities = 46/128 (35%), Positives = 73/128 (57%), Gaps = 8/128 (6%) Query: 115 ESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSIL---FSNRAAARMKQDKK 171 E+ +LKEEGN F+ DY A +SYS+AL++ K++++L + NRAA +K + Sbjct: 5 EAVQLKEEGNRHFQLQDYKAATNSYSQALKLT-----KDKALLATLYRNRAACGLKTESY 59 Query: 172 EMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMR 231 A +D S+AI +N S I+A+ RR + E KLD+A +D + +P +E R Sbjct: 60 VQAASDASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRR 119 Query: 232 LPKQIEER 239 L I+E+ Sbjct: 120 LNTSIQEK 127 >gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo sapiens] Length = 631 Score = 76.6 bits (187), Expect = 2e-14 Identities = 54/194 (27%), Positives = 94/194 (48%), Gaps = 18/194 (9%) Query: 65 DCSASFEEEPGADKVENKSNEDVNSSELDEEYLIELEKNMSDEEKQKRREESTR------ 118 + S EE +++++ E ++D L EL+K+ S E + ES Sbjct: 71 ESSKKTREENTKNRIKSYDYEAWAKLDVDR-ILDELDKDDSTHESLSQESESEEDGIHVD 129 Query: 119 ------LKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKE 172 LKE+GN+ FK+G Y EA Y++ ++ P +L +NRA+A + K Sbjct: 130 SQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPY-----NPVLPTNRASAYFRLKKFA 184 Query: 173 MAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRL 232 +A +DC+ A+ LN SY +A RR KL+EA +DY+ +LE +P+ +A ++ Sbjct: 185 VAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKI 244 Query: 233 PKQIEERNERLKEE 246 + + + +E Sbjct: 245 SQALASKENSYPKE 258 Score = 67.0 bits (162), Expect = 2e-11 Identities = 48/168 (28%), Positives = 81/168 (48%), Gaps = 6/168 (3%) Query: 69 SFEEEPGADKVENKSNEDVNSSELDEEYLIE-LEKNMSDEEKQKRREESTRLKEEGNEQF 127 +FE K+ NS + + +I+ E E Q+ ++++ K+ GN F Sbjct: 234 NFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFF 293 Query: 128 KKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSKAIQLNPS 187 K+G Y A Y+R + ++L +NRA A +K K E A DC++AI L+ S Sbjct: 294 KEGKYERAIECYTRGIAA-----DGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGS 348 Query: 188 YIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQ 235 Y +A RR KL+EA +D++++L +P QA ++ K+ Sbjct: 349 YSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKK 396 >gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo sapiens] Length = 665 Score = 76.6 bits (187), Expect = 2e-14 Identities = 54/194 (27%), Positives = 94/194 (48%), Gaps = 18/194 (9%) Query: 65 DCSASFEEEPGADKVENKSNEDVNSSELDEEYLIELEKNMSDEEKQKRREESTR------ 118 + S EE +++++ E ++D L EL+K+ S E + ES Sbjct: 71 ESSKKTREENTKNRIKSYDYEAWAKLDVDR-ILDELDKDDSTHESLSQESESEEDGIHVD 129 Query: 119 ------LKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKE 172 LKE+GN+ FK+G Y EA Y++ ++ P +L +NRA+A + K Sbjct: 130 SQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPY-----NPVLPTNRASAYFRLKKFA 184 Query: 173 MAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRL 232 +A +DC+ A+ LN SY +A RR KL+EA +DY+ +LE +P+ +A ++ Sbjct: 185 VAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKI 244 Query: 233 PKQIEERNERLKEE 246 + + + +E Sbjct: 245 SQALASKENSYPKE 258 Score = 69.7 bits (169), Expect = 3e-12 Identities = 49/172 (28%), Positives = 84/172 (48%), Gaps = 6/172 (3%) Query: 69 SFEEEPGADKVENKSNEDVNSSELDEEYLIE-LEKNMSDEEKQKRREESTRLKEEGNEQF 127 +FE K+ NS + + +I+ E E Q+ ++++ K+ GN F Sbjct: 234 NFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFF 293 Query: 128 KKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSKAIQLNPS 187 K+G Y A Y+R + ++L +NRA A +K K E A DC++AI L+ S Sbjct: 294 KEGKYERAIECYTRGIAA-----DGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGS 348 Query: 188 YIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQIEER 239 Y +A RR KL+EA +D++++L +P QA ++ K++ E+ Sbjct: 349 YSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEK 400 >gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2 [Homo sapiens] Length = 438 Score = 75.5 bits (184), Expect = 5e-14 Identities = 38/100 (38%), Positives = 63/100 (63%), Gaps = 1/100 (1%) Query: 120 KEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCS 179 KE+GN+ FK+G+Y A Y+ AL + P+ K + L+ NR K K + AI DC+ Sbjct: 204 KEDGNKAFKEGNYKLAYELYTEALGIDPNNI-KTNAKLYCNRGTVNSKLRKLDDAIEDCT 262 Query: 180 KAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKD 219 A++L+ +YI+A LRRA+ Y T++ +EA+ DY+ + + + Sbjct: 263 NAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTE 302 Score = 35.4 bits (80), Expect = 0.060 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 5/83 (6%) Query: 145 MCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDK 204 MCP + + + NRAA M + A+ D ++++L+ S++R LR + + Sbjct: 1 MCP-----KNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGN 55 Query: 205 LDEALEDYKSILEKDPSIHQARE 227 A ++ LE D QA++ Sbjct: 56 AMAACRSFQRALELDHKNAQAQQ 78 Score = 31.2 bits (69), Expect = 1.1 Identities = 39/179 (21%), Positives = 72/179 (40%), Gaps = 16/179 (8%) Query: 98 IELE-KNMSDEEKQKRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSI 156 +EL+ KN +++ K ++ F+K D+ + RALE P+C + + I Sbjct: 67 LELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFK--I 124 Query: 157 LFSNRAAARMKQDKKEMAINDCSKAIQLNPS--YIRAILRRAELYEKTDKLDEALEDYKS 214 L + A + + + +D + N Y+R + E D +++A++ + Sbjct: 125 LKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYE-----DCIEKAVQFFVQ 179 Query: 215 ILEKDPSIHQAREACMR---LPKQIEERNERLKEEMLGKLKDLGNLVLRPFGLSTENFQ 270 L P +A AC L + E+ N+ KE G K L G+ N + Sbjct: 180 ALRMAPDHEKACIACRNAKALKAKKEDGNKAFKE---GNYKLAYELYTEALGIDPNNIK 235 >gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1 [Homo sapiens] Length = 494 Score = 75.5 bits (184), Expect = 5e-14 Identities = 38/100 (38%), Positives = 63/100 (63%), Gaps = 1/100 (1%) Query: 120 KEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCS 179 KE+GN+ FK+G+Y A Y+ AL + P+ K + L+ NR K K + AI DC+ Sbjct: 260 KEDGNKAFKEGNYKLAYELYTEALGIDPNNI-KTNAKLYCNRGTVNSKLRKLDDAIEDCT 318 Query: 180 KAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKD 219 A++L+ +YI+A LRRA+ Y T++ +EA+ DY+ + + + Sbjct: 319 NAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTE 358 Score = 65.1 bits (157), Expect = 7e-11 Identities = 37/127 (29%), Positives = 67/127 (52%), Gaps = 7/127 (5%) Query: 101 EKNMSDEEKQKRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSN 160 E + D+++ KR E+ KE+GN + K DY EA + Y++A++MCP + + + N Sbjct: 15 EPELLDDQEAKREAET--FKEQGNAYYAKKDYNEAYNYYTKAIDMCP-----KNASYYGN 67 Query: 161 RAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDP 220 RAA M + A+ D ++++L+ S++R LR + + A ++ LE D Sbjct: 68 RAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDH 127 Query: 221 SIHQARE 227 QA++ Sbjct: 128 KNAQAQQ 134 Score = 31.2 bits (69), Expect = 1.1 Identities = 39/179 (21%), Positives = 72/179 (40%), Gaps = 16/179 (8%) Query: 98 IELE-KNMSDEEKQKRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSI 156 +EL+ KN +++ K ++ F+K D+ + RALE P+C + + I Sbjct: 123 LELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFK--I 180 Query: 157 LFSNRAAARMKQDKKEMAINDCSKAIQLNPS--YIRAILRRAELYEKTDKLDEALEDYKS 214 L + A + + + +D + N Y+R + E D +++A++ + Sbjct: 181 LKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYE-----DCIEKAVQFFVQ 235 Query: 215 ILEKDPSIHQAREACMR---LPKQIEERNERLKEEMLGKLKDLGNLVLRPFGLSTENFQ 270 L P +A AC L + E+ N+ KE G K L G+ N + Sbjct: 236 ALRMAPDHEKACIACRNAKALKAKKEDGNKAFKE---GNYKLAYELYTEALGIDPNNIK 291 >gi|89179321 smooth muscle cell associated protein-1 isoform 3 [Homo sapiens] Length = 929 Score = 75.1 bits (183), Expect = 7e-14 Identities = 47/153 (30%), Positives = 86/153 (56%), Gaps = 3/153 (1%) Query: 118 RLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAIND 177 +L++EGNE FK GDY A ++Y++AL + +++++L NRAA +K + + A + Sbjct: 8 QLRKEGNELFKCGDYGGALAAYTQALGL--DATPQDQAVLHRNRAACHLKLEDYDKAETE 65 Query: 178 CSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQIE 237 SKAI+ + ++A+ RR++ EK +LD+A+ D + + +P +EA + QI+ Sbjct: 66 ASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQ 125 Query: 238 ERNERLKEEMLGKLKDLGNLVLRPFGLSTENFQ 270 E+ R K++ + ++L P TE Q Sbjct: 126 EK-VRYMSSTDAKVEQMFQILLDPEEKGTEKKQ 157 >gi|29725607 smooth muscle cell associated protein-1 isoform 2 [Homo sapiens] Length = 944 Score = 75.1 bits (183), Expect = 7e-14 Identities = 47/153 (30%), Positives = 86/153 (56%), Gaps = 3/153 (1%) Query: 118 RLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAIND 177 +L++EGNE FK GDY A ++Y++AL + +++++L NRAA +K + + A + Sbjct: 23 QLRKEGNELFKCGDYGGALAAYTQALGL--DATPQDQAVLHRNRAACHLKLEDYDKAETE 80 Query: 178 CSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQIE 237 SKAI+ + ++A+ RR++ EK +LD+A+ D + + +P +EA + QI+ Sbjct: 81 ASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQ 140 Query: 238 ERNERLKEEMLGKLKDLGNLVLRPFGLSTENFQ 270 E+ R K++ + ++L P TE Q Sbjct: 141 EK-VRYMSSTDAKVEQMFQILLDPEEKGTEKKQ 172 >gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein) [Homo sapiens] Length = 543 Score = 71.2 bits (173), Expect = 1e-12 Identities = 49/166 (29%), Positives = 88/166 (53%), Gaps = 10/166 (6%) Query: 70 FEEEPGADKVE--NKSNEDVNSSELDEEYLIELEKNMSDEEKQKRREESTRLKEE--GNE 125 F+EE D + NKS + + ++ ++ + EK + ++E+ L+E+ GNE Sbjct: 311 FKEEKYKDAIHFYNKSLAEHRTPDVLKKCQ-QAEKILKEQERLAYINPDLALEEKNKGNE 369 Query: 126 QFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSKAIQLN 185 F+KGDY +A Y+ A++ P + + L+SNRAA K + ++A+ DC + IQL Sbjct: 370 CFQKGDYPQAMKHYTEAIKRNP-----KDAKLYSNRAACYTKLLEFQLALKDCEECIQLE 424 Query: 186 PSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMR 231 P++I+ R+A E +A++ Y+ L+ D S +A + R Sbjct: 425 PTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGYQR 470 Score = 60.1 bits (144), Expect = 2e-09 Identities = 35/126 (27%), Positives = 63/126 (50%), Gaps = 5/126 (3%) Query: 114 EESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEM 173 E+ LKE+GN+ G+ +A YS A+++ P +L+SNR+AA K+ + Sbjct: 2 EQVNELKEKGNKALSVGNIDDALQCYSEAIKLDP-----HNHVLYSNRSAAYAKKGDYQK 56 Query: 174 AINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLP 233 A D K + L P + + R+A E ++ +EA Y+ L+ + + Q +E + Sbjct: 57 AYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNME 116 Query: 234 KQIEER 239 ++ ER Sbjct: 117 ARLAER 122 Score = 42.7 bits (99), Expect = 4e-04 Identities = 38/167 (22%), Positives = 77/167 (46%), Gaps = 15/167 (8%) Query: 99 ELEKNMSDEEKQKRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILF 158 E + +E+ + ++++ + KE GN+ +KK D+ A Y +A E+ P+ Sbjct: 208 ETKPEPMEEDLPENKKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPT-----NMTYI 262 Query: 159 SNRAAARMKQDKKEMAINDCSKAIQLN-------PSYIRAILRRAELYEKTDKLDEALED 211 +N+AA ++ C KAI++ +A R Y K +K +A+ Sbjct: 263 TNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHF 322 Query: 212 Y-KSILE-KDPSIHQAREACMRLPKQIEERNERLKEEMLGKLKDLGN 256 Y KS+ E + P + + + ++ K+ +ER + ++ + K+ GN Sbjct: 323 YNKSLAEHRTPDVLKKCQQAEKILKE-QERLAYINPDLALEEKNKGN 368 >gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo sapiens] Length = 506 Score = 69.7 bits (169), Expect = 3e-12 Identities = 49/172 (28%), Positives = 84/172 (48%), Gaps = 6/172 (3%) Query: 69 SFEEEPGADKVENKSNEDVNSSELDEEYLIE-LEKNMSDEEKQKRREESTRLKEEGNEQF 127 +FE K+ NS + + +I+ E E Q+ ++++ K+ GN F Sbjct: 75 NFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFF 134 Query: 128 KKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSKAIQLNPS 187 K+G Y A Y+R + ++L +NRA A +K K E A DC++AI L+ S Sbjct: 135 KEGKYERAIECYTRGIAA-----DGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGS 189 Query: 188 YIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQIEER 239 Y +A RR KL+EA +D++++L +P QA ++ K++ E+ Sbjct: 190 YSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEK 241 Score = 53.1 bits (126), Expect = 3e-07 Identities = 28/91 (30%), Positives = 50/91 (54%) Query: 156 ILFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSI 215 +L +NRA+A + K +A +DC+ A+ LN SY +A RR KL+EA +DY+ + Sbjct: 9 VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERV 68 Query: 216 LEKDPSIHQAREACMRLPKQIEERNERLKEE 246 LE +P+ +A ++ + + + +E Sbjct: 69 LELEPNNFEATNELRKISQALASKENSYPKE 99 >gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] Length = 313 Score = 66.6 bits (161), Expect = 2e-11 Identities = 40/106 (37%), Positives = 57/106 (53%), Gaps = 5/106 (4%) Query: 115 ESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMA 174 E+ RLK EGNEQ K ++ A Y +A+E+ P+ ++ F NRAAA K A Sbjct: 90 EAERLKTEGNEQMKVENFEAAVHFYGKAIELNPA-----NAVYFCNRAAAYSKLGNYAGA 144 Query: 175 INDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDP 220 + DC +AI ++P+Y +A R +K EA+ YK LE DP Sbjct: 145 VQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDP 190 Score = 32.7 bits (73), Expect = 0.39 Identities = 19/61 (31%), Positives = 31/61 (50%) Query: 165 RMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQ 224 +MK + E A++ KAI+LNP+ RA Y K A++D + + DP+ + Sbjct: 101 QMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSK 160 Query: 225 A 225 A Sbjct: 161 A 161 >gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] Length = 499 Score = 65.5 bits (158), Expect = 5e-11 Identities = 42/128 (32%), Positives = 68/128 (53%), Gaps = 11/128 (8%) Query: 111 KRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDK 170 KR EE LK + N+ FK DY A YS+A+E+ PS +I + NR+ A ++ + Sbjct: 26 KRAEE---LKTQANDYFKAKDYENAIKFYSQAIELNPS-----NAIYYGNRSLAYLRTEC 77 Query: 171 KEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAR---E 227 A+ D ++AI+L+ YI+ RRA K AL DY+++++ P A+ + Sbjct: 78 YGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQ 137 Query: 228 ACMRLPKQ 235 C ++ KQ Sbjct: 138 ECNKIVKQ 145 >gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta [Homo sapiens] Length = 304 Score = 64.3 bits (155), Expect = 1e-10 Identities = 35/106 (33%), Positives = 58/106 (54%), Gaps = 5/106 (4%) Query: 115 ESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMA 174 ++ +LK+EGN K+ +Y A Y++A+E+ P+ ++ + NRAAA+ K A Sbjct: 84 KADQLKDEGNNHMKEENYAAAVDCYTQAIELDPN-----NAVYYCNRAAAQSKLGHYTDA 138 Query: 175 INDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDP 220 I DC KAI ++ Y +A R +K +EA+ Y+ L+ DP Sbjct: 139 IKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDP 184 >gi|156627581 tetratricopeptide repeat domain 4 [Homo sapiens] Length = 387 Score = 61.6 bits (148), Expect = 8e-10 Identities = 59/204 (28%), Positives = 101/204 (49%), Gaps = 34/204 (16%) Query: 55 EDQGEEECFHDCSASFEEEP-----GADKVENKSNEDVNSSELDEEYLIELEKNMSDEEK 109 EDQ E+E FE+ P +++ + N D L L+ + DEE+ Sbjct: 32 EDQWEKE--------FEKVPLFMSRAPSEIDPRENPD----------LACLQSIIFDEER 73 Query: 110 QKRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKE-RSILFSNRAAARMKQ 168 + T K+EGN+ FK+ DY +A SY+ L+ C + ++L++NRAAA+ Sbjct: 74 SPEEQAKT-YKDEGNDYFKEKDYKKAVISYTEGLKK--KCADPDLNAVLYTNRAAAQYYL 130 Query: 169 DKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEAL---EDYKSILEKDPSIHQA 225 A+ND + A +L P +++AI+R A + + EA+ ++ I K+ + + Sbjct: 131 GNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEM 190 Query: 226 REACMRLPKQIEERNER---LKEE 246 R +L K+IE+R+ R LKE+ Sbjct: 191 RAKADKL-KRIEQRDVRKANLKEK 213 >gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sapiens] Length = 504 Score = 60.8 bits (146), Expect = 1e-09 Identities = 40/134 (29%), Positives = 67/134 (50%), Gaps = 6/134 (4%) Query: 111 KRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDK 170 K+ ++ +L E E + G Y +A S Y ++ PS E ++ R +D+ Sbjct: 263 KQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSI--AEYTVRSKERICHCFSKDE 320 Query: 171 KEM-AINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSIL---EKDPSIHQAR 226 K + AI CS+ +Q+ P + A+ RAE Y + DEA++DY++ E D I + Sbjct: 321 KPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGL 380 Query: 227 EACMRLPKQIEERN 240 E RL KQ ++R+ Sbjct: 381 EKAQRLLKQSQKRD 394 Score = 58.5 bits (140), Expect = 7e-09 Identities = 39/128 (30%), Positives = 65/128 (50%), Gaps = 7/128 (5%) Query: 121 EEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSK 180 E G + G +A S + A++ P + I + RA + K + A+ D +K Sbjct: 42 ELGKKLLAAGQLADALSQFHAAVDGDPDNY-----IAYYRRATVFLAMGKSKAALPDLTK 96 Query: 181 AIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQIEERN 240 IQL + A L+R L K KLDEA +D+K +L+ +PS ++ +EA +L K + Sbjct: 97 VIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIK--SDEM 154 Query: 241 ERLKEEML 248 +RL+ + L Sbjct: 155 QRLRSQAL 162 Score = 43.5 bits (101), Expect = 2e-04 Identities = 39/166 (23%), Positives = 78/166 (46%), Gaps = 17/166 (10%) Query: 91 ELDEEYLIELEKNMSDEEKQK------RREESTRLKEEGNEQFKKGDYIEAESSYSRALE 144 E ++++ L+ N S+ E+++ + +E RL+ + F GDY A + + LE Sbjct: 123 EAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSGDYTAAIAFLDKILE 182 Query: 145 MCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDK 204 +C + E L RA +K+ + AI+D A +L A + + LY + Sbjct: 183 VC--VWDAE---LRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGD 237 Query: 205 LDEALEDYKSILEKDPSIHQAREACMRLPKQIEERNERLK--EEML 248 + +L + + L+ D Q + C KQ+++ N+ ++ EE++ Sbjct: 238 HELSLSEVRECLKLD----QDHKRCFAHYKQVKKLNKLIESAEELI 279 >gi|17149853 WAF-1/CIP1 stabilizing protein 39 [Homo sapiens] Length = 349 Score = 57.8 bits (138), Expect = 1e-08 Identities = 36/126 (28%), Positives = 61/126 (48%), Gaps = 7/126 (5%) Query: 105 SDEEKQKRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMC---PSCFQKERSILFSNR 161 + E++ REE R G E F+ G+ A Y RAL + P ER++L +N Sbjct: 203 TSEKEALAREERAR----GTELFRAGNPEGAARCYGRALRLLLTLPPPGPPERTVLHANL 258 Query: 162 AAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPS 221 AA ++ + ++A C + ++ P +++A+ RR L++A D K +L DP Sbjct: 259 AACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPK 318 Query: 222 IHQARE 227 A+E Sbjct: 319 NRAAQE 324 >gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] Length = 457 Score = 57.4 bits (137), Expect = 1e-08 Identities = 43/168 (25%), Positives = 76/168 (45%), Gaps = 13/168 (7%) Query: 99 ELEKNMSDEEKQKRREESTRLKEEGNEQFKKGDYIEAESSYSRA---LEMCPSCFQKERS 155 E K + + +++ E++ +KE+G FK G Y++A Y + LEM +KE Sbjct: 251 EKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESK 310 Query: 156 I-------LFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEA 208 F N A +K + A+ C KA+ L+ + + + RR E ++ + A Sbjct: 311 ASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESA 370 Query: 209 LEDYKSILEKDPSIHQAR---EACMRLPKQIEERNERLKEEMLGKLKD 253 D++ +LE +P AR C + K+ ER+ R+ M K + Sbjct: 371 KGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAE 418 >gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] Length = 457 Score = 57.4 bits (137), Expect = 1e-08 Identities = 43/168 (25%), Positives = 76/168 (45%), Gaps = 13/168 (7%) Query: 99 ELEKNMSDEEKQKRREESTRLKEEGNEQFKKGDYIEAESSYSRA---LEMCPSCFQKERS 155 E K + + +++ E++ +KE+G FK G Y++A Y + LEM +KE Sbjct: 251 EKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESK 310 Query: 156 I-------LFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEA 208 F N A +K + A+ C KA+ L+ + + + RR E ++ + A Sbjct: 311 ASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESA 370 Query: 209 LEDYKSILEKDPSIHQAR---EACMRLPKQIEERNERLKEEMLGKLKD 253 D++ +LE +P AR C + K+ ER+ R+ M K + Sbjct: 371 KGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAE 418 >gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] Length = 457 Score = 57.4 bits (137), Expect = 1e-08 Identities = 43/168 (25%), Positives = 76/168 (45%), Gaps = 13/168 (7%) Query: 99 ELEKNMSDEEKQKRREESTRLKEEGNEQFKKGDYIEAESSYSRA---LEMCPSCFQKERS 155 E K + + +++ E++ +KE+G FK G Y++A Y + LEM +KE Sbjct: 251 EKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESK 310 Query: 156 I-------LFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEA 208 F N A +K + A+ C KA+ L+ + + + RR E ++ + A Sbjct: 311 ASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESA 370 Query: 209 LEDYKSILEKDPSIHQAR---EACMRLPKQIEERNERLKEEMLGKLKD 253 D++ +LE +P AR C + K+ ER+ R+ M K + Sbjct: 371 KGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAE 418 >gi|19923193 heat shock 70kD protein binding protein [Homo sapiens] Length = 369 Score = 56.6 bits (135), Expect = 3e-08 Identities = 52/202 (25%), Positives = 92/202 (45%), Gaps = 29/202 (14%) Query: 71 EEEPGADKVENKSNEDVNSSE-----LDEEYLIELEKNMSDEEKQKRREESTRLKEEGNE 125 EE+P + KVE D SSE +D+E +IE + + E + E + + ++ N+ Sbjct: 57 EEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDENAEITEEMMDQAND 116 Query: 126 QFKKGDYIEA--ESSYSRALEMCPSCFQ--KERSILFSNRAAARMKQDKKEMAINDCSKA 181 KK IEA + +A+++ + +IL++ RA+ +K K AI DC +A Sbjct: 117 --KKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRA 174 Query: 182 IQLNPSYIRAILRRAELYEKTDKLDEALEDY----KSILEKDPSI--------------H 223 I++NP + R + + +EA D K ++D S H Sbjct: 175 IEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEH 234 Query: 224 QAREACMRLPKQIEERNERLKE 245 + + R ++I+ER ER+K+ Sbjct: 235 RRKYERKREEREIKERIERVKK 256 >gi|4503729 FK506 binding protein 52 [Homo sapiens] Length = 459 Score = 55.1 bits (131), Expect = 7e-08 Identities = 45/192 (23%), Positives = 86/192 (44%), Gaps = 20/192 (10%) Query: 99 ELEKNMSDEEKQKRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMC--PSCFQKE--- 153 E K + +++ E+ST +KE G FK+G Y +A Y + + S F E Sbjct: 253 EKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQ 312 Query: 154 -----RSILFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEA 208 R N A +K AI C+KA++L+ + + + RR E + + + A Sbjct: 313 KAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELA 372 Query: 209 LEDYKSILEKDPSIHQAREACMRLPKQIEERNERLKEEMLGKLKDLGNLVLRPFGLSTEN 268 D++ +L+ P+ A+ Q+ +R++ ++ + K N+ R L+ E Sbjct: 373 RADFQKVLQLYPNNKAAK-------TQLAVCQQRIRRQLAREKKLYANMFER---LAEEE 422 Query: 269 FQIKQDSSTGSY 280 + K ++S+G + Sbjct: 423 NKAKAEASSGDH 434 >gi|52630440 FK506-binding protein 8 [Homo sapiens] Length = 413 Score = 54.7 bits (130), Expect = 1e-07 Identities = 38/155 (24%), Positives = 74/155 (47%), Gaps = 15/155 (9%) Query: 110 QKRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSC------FQKERSIL------ 157 Q+R + R +E GN +++ D++ A +SY A++ S F++E +L Sbjct: 216 QERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKC 275 Query: 158 FSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILE 217 +N AA+++K D A+ CS ++ P I+A+ R+ ++ + + EA+ ++ L+ Sbjct: 276 LNNLAASQLKLDHYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALK 335 Query: 218 KDPS---IHQAREACMRLPKQIEERNERLKEEMLG 249 +PS IH ++ L +MLG Sbjct: 336 LEPSNKTIHAELSKLVKKHAAQRSTETALYRKMLG 370 >gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens] Length = 676 Score = 53.9 bits (128), Expect = 2e-07 Identities = 40/122 (32%), Positives = 59/122 (48%), Gaps = 9/122 (7%) Query: 118 RLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQD---KKEMA 174 R+K++ NE F + +A YS+A++ P ++L+ NRAAA MK+ A Sbjct: 363 RVKQQANEAFACQQWTQAIQLYSKAVQRAP-----HNAMLYGNRAAAYMKRKWDGDHYDA 417 Query: 175 INDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPK 234 + DC KAI LNP +++A R A + + EALE K P AC L + Sbjct: 418 LRDCLKAISLNPCHLKAHFRLARCLFELKYVAEALECLDDFKGKFPE-QAHSSACDALGR 476 Query: 235 QI 236 I Sbjct: 477 DI 478 >gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] Length = 2481 Score = 52.4 bits (124), Expect = 5e-07 Identities = 41/135 (30%), Positives = 68/135 (50%), Gaps = 11/135 (8%) Query: 122 EGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSKA 181 + N+ GD+ A Y+ AL + P + IL+SNR+AA MK + + A++D KA Sbjct: 64 QSNQACHDGDFHTAIVLYNEALAVDP-----QNCILYSNRSAAYMKIQQYDKALDDAIKA 118 Query: 182 IQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAR----EACMRLPKQ-- 235 LNP + +A R+ + + +AL + S L +DP Q EA M+ P + Sbjct: 119 RLLNPKWPKAYFRQGVALQYLGRHADALAAFASGLAQDPKSLQLLVGMVEAAMKSPMRDS 178 Query: 236 IEERNERLKEEMLGK 250 +E ++L++ L K Sbjct: 179 LEPTYQQLQKMKLDK 193 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.308 0.127 0.351 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,814,108 Number of Sequences: 37866 Number of extensions: 584348 Number of successful extensions: 6251 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 208 Number of HSP's successfully gapped in prelim test: 490 Number of HSP's that attempted gapping in prelim test: 3677 Number of HSP's gapped (non-prelim): 1920 length of query: 292 length of database: 18,247,518 effective HSP length: 101 effective length of query: 191 effective length of database: 14,423,052 effective search space: 2754802932 effective search space used: 2754802932 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.