Guide to the Human Genome
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Search of human proteins with 4507491

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507491 thimet oligopeptidase 1 [Homo sapiens]
         (689 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507491 thimet oligopeptidase 1 [Homo sapiens]                    1400   0.0  
gi|14149738 neurolysin [Homo sapiens]                                 902   0.0  
gi|156105687 mitochondrial intermediate peptidase [Homo sapiens]      198   1e-50
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     40   0.009
gi|153945715 myosin VC [Homo sapiens]                                  38   0.027
gi|34878904 synaptonemal complex protein 1 [Homo sapiens]              37   0.061
gi|157364947 ecotropic viral integration site 1 isoform a [Homo ...    35   0.18 
gi|157364945 ecotropic viral integration site 1 isoform b [Homo ...    35   0.18 
gi|157364943 ecotropic viral integration site 1 isoform b [Homo ...    35   0.18 
gi|4885583 Rho-associated, coiled-coil containing protein kinase...    33   1.2  
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         33   1.2  
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         33   1.2  
gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]                  33   1.2  
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    32   1.5  
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...    32   1.5  
gi|20070228 nucleobindin 1 [Homo sapiens]                              32   1.5  
gi|169208517 PREDICTED: similar to Golgin subfamily A member 8-l...    32   2.0  
gi|239745099 PREDICTED: similar to Golgin subfamily A member 8-l...    32   2.0  
gi|115648142 centrosomal protein 164kDa [Homo sapiens]                 32   2.0  
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    32   2.0  
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    32   2.0  
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    32   2.0  
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    32   2.0  
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    32   2.6  
gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens]            32   2.6  
gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]             32   2.6  
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]                       31   3.3  
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]                       31   3.3  
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]                       31   3.3  
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]                        31   3.3  

>gi|4507491 thimet oligopeptidase 1 [Homo sapiens]
          Length = 689

 Score = 1400 bits (3623), Expect = 0.0
 Identities = 689/689 (100%), Positives = 689/689 (100%)

Query: 1   MKPPAACAGDMADAASPCSVVNDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVS 60
           MKPPAACAGDMADAASPCSVVNDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVS
Sbjct: 1   MKPPAACAGDMADAASPCSVVNDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVS 60

Query: 61  YESTLKALADVEVTYTVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQ 120
           YESTLKALADVEVTYTVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQ
Sbjct: 61  YESTLKALADVEVTYTVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQ 120

Query: 121 RIVWLQEKVQKDSLRPEAARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNK 180
           RIVWLQEKVQKDSLRPEAARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNK
Sbjct: 121 RIVWLQEKVQKDSLRPEAARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNK 180

Query: 181 NLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKV 240
           NLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKV
Sbjct: 181 NLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKV 240

Query: 241 EEAFNCRCKEENCAILKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQ 300
           EEAFNCRCKEENCAILKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQ
Sbjct: 241 EEAFNCRCKEENCAILKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQ 300

Query: 301 KLKPLGEQERAVILELKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYF 360
           KLKPLGEQERAVILELKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYF
Sbjct: 301 KLKPLGEQERAVILELKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYF 360

Query: 361 PVQVVTHGLLGIYQELLGLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREG 420
           PVQVVTHGLLGIYQELLGLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREG
Sbjct: 361 PVQVVTHGLLGIYQELLGLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREG 420

Query: 421 KYGHAACFGLQPGCLRQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMH 480
           KYGHAACFGLQPGCLRQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMH
Sbjct: 421 KYGHAACFGLQPGCLRQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMH 480

Query: 481 QLCSQAEFAMFSGTHVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLI 540
           QLCSQAEFAMFSGTHVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLI
Sbjct: 481 QLCSQAEFAMFSGTHVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLI 540

Query: 541 ESRQANTGLFNLRQIVLAKVDQALHTQTDADPAEEYARLCQEILGVPATPGTNMPATFGH 600
           ESRQANTGLFNLRQIVLAKVDQALHTQTDADPAEEYARLCQEILGVPATPGTNMPATFGH
Sbjct: 541 ESRQANTGLFNLRQIVLAKVDQALHTQTDADPAEEYARLCQEILGVPATPGTNMPATFGH 600

Query: 601 LAGGYDAQYYGYLWSEVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRR 660
           LAGGYDAQYYGYLWSEVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRR
Sbjct: 601 LAGGYDAQYYGYLWSEVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRR 660

Query: 661 FLGRDPKQDAFLLSKGLQVGGCEPEPQVC 689
           FLGRDPKQDAFLLSKGLQVGGCEPEPQVC
Sbjct: 661 FLGRDPKQDAFLLSKGLQVGGCEPEPQVC 689


>gi|14149738 neurolysin [Homo sapiens]
          Length = 704

 Score =  902 bits (2330), Expect = 0.0
 Identities = 426/656 (64%), Positives = 523/656 (79%)

Query: 22  NDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNI 81
           N LRWDLS +QI+ RT ELI QTK+VYD VG    E+V+YE+ L+ALADVEV Y V+R +
Sbjct: 46  NVLRWDLSPEQIKTRTEELIVQTKQVYDAVGMLGIEEVTYENCLQALADVEVKYIVERTM 105

Query: 82  LDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARY 141
           LDFPQHVS  K++R ASTEADK+LS FD+EMSMR D+++RIV LQE      ++PEA RY
Sbjct: 106 LDFPQHVSSDKEVRAASTEADKRLSRFDIEMSMRGDIFERIVHLQETCDLGKIKPEARRY 165

Query: 142 LERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPE 201
           LE+ IK+G+RNGLHLP + Q  IK +KK++S LCIDFNKNLNED TFL F+  ELG LP+
Sbjct: 166 LEKSIKMGKRNGLHLPEQVQNEIKSMKKRMSELCIDFNKNLNEDDTFLVFSKAELGALPD 225

Query: 202 DFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENCAILKELVT 261
           DF++SLEK +D K K+TLKYPHYFP++KKC +PETRR++E AFN RCKEEN  IL++L+ 
Sbjct: 226 DFIDSLEKTDDDKYKITLKYPHYFPVMKKCCIPETRRRMEMAFNTRCKEENTIILQQLLP 285

Query: 262 LRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILELKRAEC 321
           LR + ++LLG+ THAD+VLEMN AK++  V  FLD+L+QKLKPLGE ER  IL LK+ EC
Sbjct: 286 LRTKVAKLLGYSTHADFVLEMNTAKSTSRVTAFLDDLSQKLKPLGEAEREFILNLKKKEC 345

Query: 322 ERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLLGIYQELLGLAF 381
           + RG  +DG+I AWD+ YYM Q EE +Y +DQ  LKEYFP++VVT GLL  YQELLGL+F
Sbjct: 346 KDRGFEYDGKINAWDLYYYMTQTEELKYSIDQEFLKEYFPIEVVTEGLLNTYQELLGLSF 405

Query: 382 HHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCLRQDGSR 441
                A  W++ V LYT +D A+GEV+G+FYLDLYPREGKY HAACFGLQPGCL  DGSR
Sbjct: 406 EQMTDAHVWNKSVTLYTVKDKATGEVLGQFYLDLYPREGKYNHAACFGLQPGCLLPDGSR 465

Query: 442 QIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVERDFV 501
            +A+AA+V NF++P A  PSLL+HDEV TYFHEFGHVMHQ+C+Q +FA FSGT+VE DFV
Sbjct: 466 MMAVAALVVNFSQPVAGRPSLLRHDEVRTYFHEFGHVMHQICAQTDFARFSGTNVETDFV 525

Query: 502 EAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQIVLAKVD 561
           E PSQMLENWVW+ + L R+S+HY+ GS +  +LLEKL+ SR  NTGL  LRQIVL+KVD
Sbjct: 526 EVPSQMLENWVWDVDSLRRLSKHYKDGSPIADDLLEKLVASRLVNTGLLTLRQIVLSKVD 585

Query: 562 QALHTQTDADPAEEYARLCQEILGVPATPGTNMPATFGHLAGGYDAQYYGYLWSEVYSMD 621
           Q+LHT T  D A EYA+ C EILGV ATPGTNMPATFGHLAGGYD QYYGYLWSEV+SMD
Sbjct: 586 QSLHTNTSLDAASEYAKYCSEILGVAATPGTNMPATFGHLAGGYDGQYYGYLWSEVFSMD 645

Query: 622 MFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRDPKQDAFLLSKGL 677
           MF++ FK+EG++N +VGM YR+ IL+PGGS D   ML  FL R+P Q AFL+S+GL
Sbjct: 646 MFYSCFKKEGIMNPEVGMKYRNLILKPGGSLDGMDMLHNFLKREPNQKAFLMSRGL 701


>gi|156105687 mitochondrial intermediate peptidase [Homo sapiens]
          Length = 713

 Score =  198 bits (504), Expect = 1e-50
 Identities = 161/605 (26%), Positives = 271/605 (44%), Gaps = 42/605 (6%)

Query: 80  NILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIV-WLQEKVQKDSLRPEA 138
           ++ DF +   P    R A+ EA + +     +++   D+YQ +   L +K   DSL PE 
Sbjct: 120 DLADFVKIAHPEPAFREAAEEACRSIGTMVEKLNTNVDLYQSLQKLLADKKLVDSLDPET 179

Query: 139 ARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFN-KNLNEDTTFLPFTLQELG 197
            R  E  +     +G+HL +E ++             +D N K L+  +TFL  T     
Sbjct: 180 RRVAELFMFDFEISGIHLDKEKRKR-----------AVDLNVKILDLSSTFLMGT----- 223

Query: 198 GLPEDFLNSLEKM---EDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENCA 254
               +F N +EK    E  +   T    H   ++   H       V EA        N  
Sbjct: 224 ----NFPNKIEKHLLPEHIRRNFTSAGDHI--IIDGLHAESPDDLVREAAYKIFLYPNAG 277

Query: 255 ILK---ELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERA 311
            LK   EL++ R   ++L+G+ T +   L+  +AK  +TV  FL++L+ KL     ++  
Sbjct: 278 QLKCLEELLSSRDLLAKLVGYSTFSHRALQGTIAKNPETVMQFLEKLSDKLSERTLKDFE 337

Query: 312 VILELKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLLG 371
           +I  +K      +  P +  +  WD  YY   +   RY ++ +L   +F +     GL  
Sbjct: 338 MIRGMKM-----KLNPQNSEVMPWDPPYYSGVIRAERYNIEPSLYCPFFSLGACMEGLNI 392

Query: 372 IYQELLGLAFHHEEGASA--WHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFG 429
           +   LLG++ + E+ A    W EDVR       + G ++G  Y D + R  K      F 
Sbjct: 393 LLNRLLGISLYAEQPAKGEVWSEDVRKLAVVHESEG-LLGYIYCDFFQRADKPHQDCHFT 451

Query: 430 LQPGCLRQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFA 489
           ++ G L++DG  Q+ +  ++ N  + +  +P+LL    +E  FHE GH MH +  +  + 
Sbjct: 452 IRGGRLKEDGDYQLPVVVLMLNLPRSSRSSPTLLTPGMMENLFHEMGHAMHSMLGRTRYQ 511

Query: 490 MFSGTHVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGL 549
             +GT    DF E PS ++E +  +   + + +RHY+TG  +P+ ++ +L ES++     
Sbjct: 512 HVTGTRCPTDFAEVPSILMEYFANDYRVVNQFARHYQTGQPLPKNMVSRLCESKKVCAAA 571

Query: 550 FNLRQIVLAKVDQALHTQTD-ADPAEEYARLCQE-ILGVPATPGTNMPATFGHLAGGYDA 607
               Q+  A +DQ  H +    +   +  +  QE   G+P  P T     F HL  GY A
Sbjct: 572 DMQLQVFYATLDQIYHGKHPLRNSTTDILKETQEKFYGLPYVPNTAWQLRFSHLV-GYGA 630

Query: 608 QYYGYLWSEVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRDPK 667
           +YY YL S   +  ++   F Q+   N   G  YR  +L  GG  +   M+   L + P 
Sbjct: 631 RYYSYLMSRAVASMVWKECFLQD-PFNRAAGERYRREMLAHGGGREPMLMVEGMLQKCPS 689

Query: 668 QDAFL 672
            D F+
Sbjct: 690 VDDFV 694


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 58/242 (23%), Positives = 103/242 (42%), Gaps = 43/242 (17%)

Query: 100  EADKKLSEFDVEMSMREDVYQRIVWLQEK-VQKDSLRPEAARYLERLIKLGRRNGLHLPR 158
            E  +K+  F  E   +E++ + I WL+E+ V++D+   E    L       ++   H+  
Sbjct: 1075 ELKQKILLFGCE---KEEMNKEITWLKEEGVKQDTTLNELQEQL-------KQKSAHVNS 1124

Query: 159  ETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDGKLKVT 218
              Q+  K +K  L  L +D NK+L E+ TFL   L EL  L E+    + ++   KLK T
Sbjct: 1125 LAQDETK-LKAHLEKLEVDLNKSLKEN-TFLQEQLVELKMLAEEDKRKVSEL-TSKLKTT 1181

Query: 219  LKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENCAI----------------LKELVTL 262
                  F  LK  H    +   +++   +   E  AI                  EL+ +
Sbjct: 1182 ---DEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINI 1238

Query: 263  RAQKSR-LLGFHTHADY----VLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILELK 317
             + K+  +L   +H  +    V E  + KT       + EL  +L+ L E++  + +  +
Sbjct: 1239 SSSKTNAILSRISHCQHRTTKVKEALLIKTCT-----VSELEAQLRQLTEEQNTLNISFQ 1293

Query: 318  RA 319
            +A
Sbjct: 1294 QA 1295


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score = 38.1 bits (87), Expect = 0.027
 Identities = 71/362 (19%), Positives = 138/362 (38%), Gaps = 64/362 (17%)

Query: 31   QQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILDFPQHVSP 90
            +QI+ + +E  E+ K   D +  Q F+DV  E               QR +L+       
Sbjct: 973  EQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEER-------------QRMLLE------- 1012

Query: 91   SKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWL--QEKVQKDSLRPEAARY------- 141
             K     + + +K++     E+   +D   ++  L   E V  D L+ E AR        
Sbjct: 1013 -KSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTI 1071

Query: 142  --LERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGL 199
               E+ I+L +   + + +  Q   + +++K+S +     ++ + +      ++++L  L
Sbjct: 1072 SEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHL 1131

Query: 200  PEDFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRC----------- 248
             ED    L    +G  K T     +F   K C+  E      EA N +            
Sbjct: 1132 NED--GELWFAYEGLKKATRVLESHFQSQKDCYEKEI-----EALNFKVVHLSQEINHLQ 1184

Query: 249  ---KEENC---AILKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKL 302
               +EEN    +I  E+  L ++   +  F           + K  Q +   L+E A+K+
Sbjct: 1185 KLFREENDINESIRHEVTRLTSENMMIPDFKQQIS-----ELEKQKQDLEIRLNEQAEKM 1239

Query: 303  K-PLGEQERAVILELKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFP 361
            K  L E    +    +    +R+ L     I   +    +++++E +   D   LK+ F 
Sbjct: 1240 KGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDH--LKKQFE 1297

Query: 362  VQ 363
             +
Sbjct: 1298 TE 1299


>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
          Length = 976

 Score = 37.0 bits (84), Expect = 0.061
 Identities = 74/361 (20%), Positives = 149/361 (41%), Gaps = 41/361 (11%)

Query: 35  ERTRELIE-QTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILDFPQHVSPSKD 93
           +  R++IE Q K + +     E   +  E  ++   D+       R++ +  +       
Sbjct: 135 QENRKIIEAQRKAIQELQFGNEKVSLKLEEGIQENKDLIKENNATRHLCNLLKETCARSA 194

Query: 94  IRTASTEADKKLSEFDVEMSMREDVYQRIVWLQE-KVQKDSLRPEAARYLERLIKLGRRN 152
            +T   E +++ +   V M +  ++ + I   +E +VQ ++ R E    +   +K     
Sbjct: 195 EKTKKYEYEREETR-QVYMDLNNNIEKMITAFEELRVQAENSRLE----MHFKLKEDYEK 249

Query: 153 GLHLPRETQENIKRIKKKLSLLCIDFNKNLN--EDTTFLPFTLQELGGLPEDFLNSLE-- 208
             HL +E ++ I   +K++SLL I   +  N  +D TFL   L+E      D +N LE  
Sbjct: 250 IQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFL---LEE----SRDKVNQLEEK 302

Query: 209 -KMEDGKLKVTLKYPHYFPL-LKKCHVP-----ETRRKVEEAFNCRCKEENCAILKELVT 261
            K++   LK +++  H+    L+   V       T++ +EE      K   C + +E  T
Sbjct: 303 TKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATK-TICQLTEEKET 361

Query: 262 LRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILELKRAEC 321
              + ++    H+      E  +    + + T      Q+L+   +Q + + +EL++   
Sbjct: 362 QMEESNKARAAHSFVVTEFETTVCSLEELLRT----EQQRLEKNEDQLKILTMELQKKSS 417

Query: 322 ---ERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLLGIYQELLG 378
              E   L  +  +   +++  + + E         LL E    + +   L G  QEL+G
Sbjct: 418 ELEEMTKLTNNKEVELEELKKVLGEKE--------TLLYENKQFEKIAEELKGTEQELIG 469

Query: 379 L 379
           L
Sbjct: 470 L 470


>gi|157364947 ecotropic viral integration site 1 isoform a [Homo
           sapiens]
          Length = 1115

 Score = 35.4 bits (80), Expect = 0.18
 Identities = 45/189 (23%), Positives = 76/189 (40%), Gaps = 25/189 (13%)

Query: 63  STLKALADVEVTYTVQRNILDFPQHVSPSKDIRTASTE----ADKKLSEFDVEMSMREDV 118
           S +K L+  E T   Q  ++  PQ +  ++DI  A ++     D K  E   E S  E  
Sbjct: 386 SPVKGLSSTEQTNKSQSPLMTHPQILPATQDILKALSKHPSVGDNKPVELQPERSSEERP 445

Query: 119 YQRIVWLQEKVQKDSLRPEAARYLERLIKLGRRNGLHLPRET-QENIKRIKKKLS----L 173
           +++I    E    D +   +   LE        + +   +E  +EN K  K K+S    L
Sbjct: 446 FEKISDQSESSDLDDVSTPSGSDLETTSGSDLESDIESDKEKFKENGKMFKDKVSPLQNL 505

Query: 174 LCIDFNKNLNEDTTFLPF-------------TLQELGGLPEDFLNS--LEKMEDGKLKVT 218
             I+  K  +  + F P              +++ +  + E +  S  L  ++D K+   
Sbjct: 506 ASINNKKEYSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVG-A 564

Query: 219 LKYPHYFPL 227
           L YP  FPL
Sbjct: 565 LPYPSMFPL 573


>gi|157364945 ecotropic viral integration site 1 isoform b [Homo
           sapiens]
          Length = 1051

 Score = 35.4 bits (80), Expect = 0.18
 Identities = 45/189 (23%), Positives = 76/189 (40%), Gaps = 25/189 (13%)

Query: 63  STLKALADVEVTYTVQRNILDFPQHVSPSKDIRTASTE----ADKKLSEFDVEMSMREDV 118
           S +K L+  E T   Q  ++  PQ +  ++DI  A ++     D K  E   E S  E  
Sbjct: 322 SPVKGLSSTEQTNKSQSPLMTHPQILPATQDILKALSKHPSVGDNKPVELQPERSSEERP 381

Query: 119 YQRIVWLQEKVQKDSLRPEAARYLERLIKLGRRNGLHLPRET-QENIKRIKKKLS----L 173
           +++I    E    D +   +   LE        + +   +E  +EN K  K K+S    L
Sbjct: 382 FEKISDQSESSDLDDVSTPSGSDLETTSGSDLESDIESDKEKFKENGKMFKDKVSPLQNL 441

Query: 174 LCIDFNKNLNEDTTFLPF-------------TLQELGGLPEDFLNS--LEKMEDGKLKVT 218
             I+  K  +  + F P              +++ +  + E +  S  L  ++D K+   
Sbjct: 442 ASINNKKEYSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVG-A 500

Query: 219 LKYPHYFPL 227
           L YP  FPL
Sbjct: 501 LPYPSMFPL 509


>gi|157364943 ecotropic viral integration site 1 isoform b [Homo
           sapiens]
          Length = 1051

 Score = 35.4 bits (80), Expect = 0.18
 Identities = 45/189 (23%), Positives = 76/189 (40%), Gaps = 25/189 (13%)

Query: 63  STLKALADVEVTYTVQRNILDFPQHVSPSKDIRTASTE----ADKKLSEFDVEMSMREDV 118
           S +K L+  E T   Q  ++  PQ +  ++DI  A ++     D K  E   E S  E  
Sbjct: 322 SPVKGLSSTEQTNKSQSPLMTHPQILPATQDILKALSKHPSVGDNKPVELQPERSSEERP 381

Query: 119 YQRIVWLQEKVQKDSLRPEAARYLERLIKLGRRNGLHLPRET-QENIKRIKKKLS----L 173
           +++I    E    D +   +   LE        + +   +E  +EN K  K K+S    L
Sbjct: 382 FEKISDQSESSDLDDVSTPSGSDLETTSGSDLESDIESDKEKFKENGKMFKDKVSPLQNL 441

Query: 174 LCIDFNKNLNEDTTFLPF-------------TLQELGGLPEDFLNS--LEKMEDGKLKVT 218
             I+  K  +  + F P              +++ +  + E +  S  L  ++D K+   
Sbjct: 442 ASINNKKEYSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVG-A 500

Query: 219 LKYPHYFPL 227
           L YP  FPL
Sbjct: 501 LPYPSMFPL 509


>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
           [Homo sapiens]
          Length = 1354

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 85/347 (24%), Positives = 136/347 (39%), Gaps = 57/347 (16%)

Query: 5   AACAGDMADAASPCSVVNDLRWDLSAQQIE----ERTRELIE-QTKRVYDQVGTQEFE-- 57
           A    +  D      ++ DL+  +++ Q E    +   E +E + K   D +   E E  
Sbjct: 608 AILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKN 667

Query: 58  ----DVSYESTLKALA-----DVEVTYTVQRNILDFPQHVSPSKDIRTASTEADKKLSEF 108
               D++Y+  LK+L      +V      +  + D  Q +  +K +  A  E +KKL E 
Sbjct: 668 NLEIDLNYK--LKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSV--AMCEMEKKLKE- 722

Query: 109 DVEMSMREDVYQRIVWLQEKVQK-DSLRPEAARYLERLIKLGRR-----NGLHLPRETQE 162
             E   RE    R+V ++++    D    ++ + LE L     R       L L  E QE
Sbjct: 723 --EREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLE-QE 779

Query: 163 NIKRI----KKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDG----- 213
           + KR+    + K      D  K L +       TL E   L E  L  L K   G     
Sbjct: 780 SNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQM 839

Query: 214 -KLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENCAILKELVTLRAQKSRLLGF 272
            +L+  L+   YF  L K  V E + ++E        E+N   LK++  L+ +K  L   
Sbjct: 840 RELQDQLEAEQYFSTLYKTQVKELKEEIE--------EKNRENLKKIQELQNEKETLA-- 889

Query: 273 HTHADYVLEMNMAKTSQTVATFLD----ELAQKLKPLGEQERAVILE 315
            T  D  L    A++ Q     L+    EL Q+ K    + R  I +
Sbjct: 890 -TQLD--LAETKAESEQLARGLLEEQYFELTQESKKAASRNRQEITD 933


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 16/50 (32%), Positives = 27/50 (54%)

Query: 541  ESRQANTGLFNLRQIVLAKVDQALHTQTDADPAEEYARLCQEILGVPATP 590
            E+      + NL++IV  KV  AL +Q   +  +EYA+ CQ+   + + P
Sbjct: 2532 ETEMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEP 2581


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 16/50 (32%), Positives = 27/50 (54%)

Query: 541  ESRQANTGLFNLRQIVLAKVDQALHTQTDADPAEEYARLCQEILGVPATP 590
            E+      + NL++IV  KV  AL +Q   +  +EYA+ CQ+   + + P
Sbjct: 2524 ETEMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEP 2573


>gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]
          Length = 1726

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 49/209 (23%), Positives = 81/209 (38%), Gaps = 13/209 (6%)

Query: 8    AGDMADAASPCSVVNDLRWDLS-AQQIEERTRELIEQTKRV-YDQVGTQEFEDVSYESTL 65
            AG+  DA      V  +  +L   QQ+     EL++    + Y      E E   Y   L
Sbjct: 851  AGENRDAQMLIEDVKRIVHELDQGQQLSSIGVELVDNELAILYMNSKKSEAEFRDYPPVL 910

Query: 66   KALADVEVTYTVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWL 125
            +    V +   +Q  +++F Q  S  +DI          L E  V+  +   +Y   +  
Sbjct: 911  RQA--VSLARRIQDPLIEFAQVCSSDEDILCLKFHP---LQEHVVKEELLNALYCEFINR 965

Query: 126  QEKVQKDSLRPEAARYLERLIK----LGRRNGLHLPRETQENIKRIKKKLSL--LCIDFN 179
              +V  D  R  A  Y + LI+    LG R G HL +  ++N  R++ +  L  +C    
Sbjct: 966  VNEVGVDVNRAIAHPYSQALIQYVCGLGPRKGTHLLKILKQNNTRLESRTQLVTMCHMGP 1025

Query: 180  KNLNEDTTFLPFTLQELGGLPEDFLNSLE 208
            K       FL      LG   + ++  L+
Sbjct: 1026 KVFMNCAGFLKIDTASLGDSTDSYIEVLD 1054


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
            [Homo sapiens]
          Length = 6907

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 50/222 (22%), Positives = 93/222 (41%), Gaps = 32/222 (14%)

Query: 69   ADVEVTYTVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEK 128
            A +++ YT+Q  +    ++ +  +  +   TEA++ L  +     M ED+Y  +  + E 
Sbjct: 3325 AKLQLQYTLQELV---SKNSAMKEAFKAQETEAERYLENYKCYRKMEEDIYTNLSKM-ET 3380

Query: 129  VQKDSLRPEAARYLERLIKLGRRNGLHLPR-ETQENIKRIKKKLSLLCIDFNKNLNEDTT 187
            V   S+      Y E L +L +   L      T+E + ++++ L LL +   +N   D  
Sbjct: 3381 VLGQSMSSLPLSYREALERLEQSKALVSNLISTKEELMKLRQILRLLRLRCTEN---DGI 3437

Query: 188  FLPFTLQELGGLPEDFLNSLEKMED-----GKLKVTLKY---------------PHYFPL 227
             L   L+ +  L E +L+ LE  ++      +LK   K+                   P 
Sbjct: 3438 CL---LKIVSALWEKWLSLLEAAKEWEMWCEELKQEWKFVSEEIEREAIILDNLQEELPE 3494

Query: 228  LKKCHVPETRRKVEEAFNCRCK-EENCAILKELVTLRAQKSR 268
            + K     T  ++ E  +C C+  EN    + L+TL  Q+ R
Sbjct: 3495 ISKTKEAATTEELSELLDCLCQYGENVEKQQLLLTLLLQRIR 3536


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
            [Homo sapiens]
          Length = 6885

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 50/222 (22%), Positives = 93/222 (41%), Gaps = 32/222 (14%)

Query: 69   ADVEVTYTVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEK 128
            A +++ YT+Q  +    ++ +  +  +   TEA++ L  +     M ED+Y  +  + E 
Sbjct: 3325 AKLQLQYTLQELV---SKNSAMKEAFKAQETEAERYLENYKCYRKMEEDIYTNLSKM-ET 3380

Query: 129  VQKDSLRPEAARYLERLIKLGRRNGLHLPR-ETQENIKRIKKKLSLLCIDFNKNLNEDTT 187
            V   S+      Y E L +L +   L      T+E + ++++ L LL +   +N   D  
Sbjct: 3381 VLGQSMSSLPLSYREALERLEQSKALVSNLISTKEELMKLRQILRLLRLRCTEN---DGI 3437

Query: 188  FLPFTLQELGGLPEDFLNSLEKMED-----GKLKVTLKY---------------PHYFPL 227
             L   L+ +  L E +L+ LE  ++      +LK   K+                   P 
Sbjct: 3438 CL---LKIVSALWEKWLSLLEAAKEWEMWCEELKQEWKFVSEEIEREAIILDNLQEELPE 3494

Query: 228  LKKCHVPETRRKVEEAFNCRCK-EENCAILKELVTLRAQKSR 268
            + K     T  ++ E  +C C+  EN    + L+TL  Q+ R
Sbjct: 3495 ISKTKEAATTEELSELLDCLCQYGENVEKQQLLLTLLLQRIR 3536


>gi|20070228 nucleobindin 1 [Homo sapiens]
          Length = 461

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 68/317 (21%), Positives = 125/317 (39%), Gaps = 40/317 (12%)

Query: 37  TRELIEQTKRVYDQVGTQEFEDVS-YESTLKALADVEVTYTVQ---RNILDFPQHVSP-- 90
           +REL   +  V  ++   + ++VS     LKA  D E    VQ    N+L   +H+ P  
Sbjct: 86  SRELDFVSHHVRTKLDELKRQEVSRLRMLLKAKMDAEQDPNVQVDHLNLLKQFEHLDPQN 145

Query: 91  -----SKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARYLERL 145
                ++D+      A + L+++D         Y+ +   + +   +SL  E  +  ER 
Sbjct: 146 QHTFEARDLELLIQTATRDLAQYDAAHHEEFKRYEMLKEHERRRYLESLGEEQRKEAERK 205

Query: 146 IKLGRRNGLHLPR----ETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPE 201
           ++  +R     P+     +Q  +K + ++L  L  D N+  N  T F+   +   G L E
Sbjct: 206 LEEQQRRHREHPKVNVPGSQAQLKEVWEELDGL--DPNR-FNPKTFFILHDINSDGVLDE 262

Query: 202 D-----FLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENCAIL 256
                 F   LEK+ D K        +    +++      R +     N    ++    L
Sbjct: 263 QELEALFTKELEKVYDPK--------NEEDDMREMEEERLRMREHVMKNVDTNQDRLVTL 314

Query: 257 KELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELA-------QKLKPLGEQE 309
           +E +    +K    G        +EM+ A T + +  F +ELA        K + L ++ 
Sbjct: 315 EEFLASTQRKE--FGDTGEGWETVEMHPAYTEEELRRFEEELAAREAELNAKAQRLSQET 372

Query: 310 RAVILELKRAECERRGL 326
            A+     R E ++R L
Sbjct: 373 EALGRSQGRLEAQKREL 389


>gi|169208517 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 2 [Homo sapiens]
          Length = 602

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 39/152 (25%), Positives = 69/152 (45%), Gaps = 38/152 (25%)

Query: 29  SAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILDFPQHV 88
           S +  EE++++L  + +    + G  E E V        L+DV  T   + N L      
Sbjct: 154 SLRYFEEKSKDLAVRLQHSLQRKG--ELESV--------LSDVMATQKKKANQLS----- 198

Query: 89  SPSKDIRTASTEADKKLSEFDVEMSMREDVYQRI-----------VWLQEKVQKDSLRPE 137
           SPSK    A TE       + +E SMRE+   ++           V L+     + L+ E
Sbjct: 199 SPSK----AGTE-------WKLEQSMREEALLKVQLTQLKESFQQVQLERDEYSEHLKGE 247

Query: 138 AARYLERLIKLGRRNGLHLPRETQENIKRIKK 169
            AR+ +R+ K+ +     L +E Q++++R++K
Sbjct: 248 RARWQQRMRKMSQEI-CTLKKEKQQDMRRVEK 278


>gi|239745099 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 1 [Homo sapiens]
          Length = 632

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 39/152 (25%), Positives = 69/152 (45%), Gaps = 38/152 (25%)

Query: 29  SAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILDFPQHV 88
           S +  EE++++L  + +    + G  E E V        L+DV  T   + N L      
Sbjct: 155 SLRYFEEKSKDLAVRLQHSLQRKG--ELESV--------LSDVMATQKKKANQLS----- 199

Query: 89  SPSKDIRTASTEADKKLSEFDVEMSMREDVYQRI-----------VWLQEKVQKDSLRPE 137
           SPSK    A TE       + +E SMRE+   ++           V L+     + L+ E
Sbjct: 200 SPSK----AGTE-------WKLEQSMREEALLKVQLTQLKESFQQVQLERDEYSEHLKGE 248

Query: 138 AARYLERLIKLGRRNGLHLPRETQENIKRIKK 169
            AR+ +R+ K+ +     L +E Q++++R++K
Sbjct: 249 RARWQQRMRKMSQEI-CTLKKEKQQDMRRVEK 279


>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
          Length = 1460

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 52/210 (24%), Positives = 86/210 (40%), Gaps = 29/210 (13%)

Query: 111 EMSMREDVYQRIVWLQEKVQ------KDSLRPEAARYLERLIKLGRRNGLHLPRETQENI 164
           E  MRE+  QR+ WL+ +VQ      +D +R E    L++L     R  L   ++ +   
Sbjct: 659 EARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKL-----REELESQQKAERAS 713

Query: 165 KRIKKKLSLLCIDFNKNLNEDTTFLPFTLQ-ELGGLPEDFLNSLEKMEDGKLK---VTLK 220
              K +  L      + L E+      + Q  L    E  L  L +  +G+ K    TL+
Sbjct: 714 LEQKNRQML------EQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLE 767

Query: 221 YPHYFPLLKKCHVPETRRKVEEAFNCRCKEENCAILKELVTLRAQKSRLLGFHTHADYVL 280
             H   L + C   E + +  E  +   K+   A  KE     AQ  + LG   H  +  
Sbjct: 768 KEHSAELERLCSSLEAKHR--EVVSSLQKKIQEAQQKE----EAQLQKCLGQVEHRVHQK 821

Query: 281 EMNMAKTSQTVATFLDELAQKLKPLGEQER 310
             ++A     +++ L E  Q+++  GE ER
Sbjct: 822 SYHVAGYEHELSSLLREKRQEVE--GEHER 849


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 70/340 (20%), Positives = 132/340 (38%), Gaps = 66/340 (19%)

Query: 31   QQIEERTRELIEQTKRVYDQVGTQE-------FEDVSYESTLKALADVEVTYTVQRNILD 83
            QQ++   +++ +Q   + +Q+  +E        E V+ E+ +K L D  +    Q N L 
Sbjct: 939  QQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLS 998

Query: 84   FPQHVSPSK--DIRTASTEADKK--------------LSEFDVEMSMREDVYQRIVWLQE 127
              + +   +  D+ T   E ++K              +SE +V +   E   Q +  L+ 
Sbjct: 999  KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1058

Query: 128  KVQKDS---------LRPEAARYLERLIK----------------LGRRNGLHLPRETQE 162
            K++ D+         L+ + A    +L K                  + N L   RE + 
Sbjct: 1059 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1118

Query: 163  NIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDGKLKVTLKYP 222
            +I  +++ L       NK   +    L   L+ L    ED L+S    ++    +  K  
Sbjct: 1119 HISDLQEDLDSERAARNK-AEKQKRDLGEELEALKTELEDTLDSTATQQE----LRAKRE 1173

Query: 223  HYFPLLKKCHVPETRRKVEEAFNCRCKEENCAILKELVTLRAQKSRLLGFHTHADYVLEM 282
                +LKK    ETR    EA     ++++   ++EL     Q  R            + 
Sbjct: 1174 QEVTVLKKALDEETRS--HEAQVQEMRQKHAQAVEELTEQLEQFKRA-----------KA 1220

Query: 283  NMAKTSQTVATFLDELAQKLKPLGEQERAVILELKRAECE 322
            N+ K  QT+     +LA +L+ LG+ ++ V  + K+ E +
Sbjct: 1221 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1260


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 70/340 (20%), Positives = 132/340 (38%), Gaps = 66/340 (19%)

Query: 31   QQIEERTRELIEQTKRVYDQVGTQE-------FEDVSYESTLKALADVEVTYTVQRNILD 83
            QQ++   +++ +Q   + +Q+  +E        E V+ E+ +K L D  +    Q N L 
Sbjct: 946  QQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLS 1005

Query: 84   FPQHVSPSK--DIRTASTEADKK--------------LSEFDVEMSMREDVYQRIVWLQE 127
              + +   +  D+ T   E ++K              +SE +V +   E   Q +  L+ 
Sbjct: 1006 KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1065

Query: 128  KVQKDS---------LRPEAARYLERLIK----------------LGRRNGLHLPRETQE 162
            K++ D+         L+ + A    +L K                  + N L   RE + 
Sbjct: 1066 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1125

Query: 163  NIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDGKLKVTLKYP 222
            +I  +++ L       NK   +    L   L+ L    ED L+S    ++    +  K  
Sbjct: 1126 HISDLQEDLDSERAARNK-AEKQKRDLGEELEALKTELEDTLDSTATQQE----LRAKRE 1180

Query: 223  HYFPLLKKCHVPETRRKVEEAFNCRCKEENCAILKELVTLRAQKSRLLGFHTHADYVLEM 282
                +LKK    ETR    EA     ++++   ++EL     Q  R            + 
Sbjct: 1181 QEVTVLKKALDEETRS--HEAQVQEMRQKHAQAVEELTEQLEQFKRA-----------KA 1227

Query: 283  NMAKTSQTVATFLDELAQKLKPLGEQERAVILELKRAECE 322
            N+ K  QT+     +LA +L+ LG+ ++ V  + K+ E +
Sbjct: 1228 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1267


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 70/340 (20%), Positives = 132/340 (38%), Gaps = 66/340 (19%)

Query: 31   QQIEERTRELIEQTKRVYDQVGTQE-------FEDVSYESTLKALADVEVTYTVQRNILD 83
            QQ++   +++ +Q   + +Q+  +E        E V+ E+ +K L D  +    Q N L 
Sbjct: 946  QQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLS 1005

Query: 84   FPQHVSPSK--DIRTASTEADKK--------------LSEFDVEMSMREDVYQRIVWLQE 127
              + +   +  D+ T   E ++K              +SE +V +   E   Q +  L+ 
Sbjct: 1006 KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1065

Query: 128  KVQKDS---------LRPEAARYLERLIK----------------LGRRNGLHLPRETQE 162
            K++ D+         L+ + A    +L K                  + N L   RE + 
Sbjct: 1066 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1125

Query: 163  NIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDGKLKVTLKYP 222
            +I  +++ L       NK   +    L   L+ L    ED L+S    ++    +  K  
Sbjct: 1126 HISDLQEDLDSERAARNK-AEKQKRDLGEELEALKTELEDTLDSTATQQE----LRAKRE 1180

Query: 223  HYFPLLKKCHVPETRRKVEEAFNCRCKEENCAILKELVTLRAQKSRLLGFHTHADYVLEM 282
                +LKK    ETR    EA     ++++   ++EL     Q  R            + 
Sbjct: 1181 QEVTVLKKALDEETRS--HEAQVQEMRQKHAQAVEELTEQLEQFKRA-----------KA 1227

Query: 283  NMAKTSQTVATFLDELAQKLKPLGEQERAVILELKRAECE 322
            N+ K  QT+     +LA +L+ LG+ ++ V  + K+ E +
Sbjct: 1228 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1267


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 70/340 (20%), Positives = 132/340 (38%), Gaps = 66/340 (19%)

Query: 31   QQIEERTRELIEQTKRVYDQVGTQE-------FEDVSYESTLKALADVEVTYTVQRNILD 83
            QQ++   +++ +Q   + +Q+  +E        E V+ E+ +K L D  +    Q N L 
Sbjct: 939  QQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLS 998

Query: 84   FPQHVSPSK--DIRTASTEADKK--------------LSEFDVEMSMREDVYQRIVWLQE 127
              + +   +  D+ T   E ++K              +SE +V +   E   Q +  L+ 
Sbjct: 999  KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1058

Query: 128  KVQKDS---------LRPEAARYLERLIK----------------LGRRNGLHLPRETQE 162
            K++ D+         L+ + A    +L K                  + N L   RE + 
Sbjct: 1059 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1118

Query: 163  NIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDGKLKVTLKYP 222
            +I  +++ L       NK   +    L   L+ L    ED L+S    ++    +  K  
Sbjct: 1119 HISDLQEDLDSERAARNK-AEKQKRDLGEELEALKTELEDTLDSTATQQE----LRAKRE 1173

Query: 223  HYFPLLKKCHVPETRRKVEEAFNCRCKEENCAILKELVTLRAQKSRLLGFHTHADYVLEM 282
                +LKK    ETR    EA     ++++   ++EL     Q  R            + 
Sbjct: 1174 QEVTVLKKALDEETRS--HEAQVQEMRQKHAQAVEELTEQLEQFKRA-----------KA 1220

Query: 283  NMAKTSQTVATFLDELAQKLKPLGEQERAVILELKRAECE 322
            N+ K  QT+     +LA +L+ LG+ ++ V  + K+ E +
Sbjct: 1221 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1260


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 31.6 bits (70), Expect = 2.6
 Identities = 30/146 (20%), Positives = 67/146 (45%), Gaps = 18/146 (12%)

Query: 26  WDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILDFP 85
           W+   Q+ EE+ RE  E+ +   +++  Q  E++ +E   K     E+ +  +  +    
Sbjct: 312 WEEKIQEQEEKIREQEEKIREQEEKMRRQ--EEMMWEKEEKMRRQEEMMWEKEEKM---- 365

Query: 86  QHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARYLERL 145
                 + +     E ++K+ E + +M  +E + ++    +EK Q++    E  +  E+ 
Sbjct: 366 ------RRLEEMMWEKEEKIRELEEKMHEQEKIREQ----EEKRQEEEKIREQEKRQEQE 415

Query: 146 IKLGRRNGLHLPRETQENIKRIKKKL 171
            K+ R+      RE +E I+  +KK+
Sbjct: 416 AKMWRQE--EKIREQEEKIREQEKKM 439


>gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens]
          Length = 885

 Score = 31.6 bits (70), Expect = 2.6
 Identities = 27/121 (22%), Positives = 51/121 (42%), Gaps = 28/121 (23%)

Query: 81  ILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSM-------------------------- 114
           ++ FP+ V  S++ RT S++A   +   DVE +                           
Sbjct: 491 VMCFPKGVPRSQEARTESSQASDMMDTMDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGR 550

Query: 115 REDVYQRIVWLQEKVQKDSLRPEAARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLL 174
           ++D  ++ + L  KVQK   +    +   R +K  R+ G  +P++  ENI   + +L + 
Sbjct: 551 KKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKRGPRIPKD--ENINFKQSELPVT 608

Query: 175 C 175
           C
Sbjct: 609 C 609


>gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]
          Length = 879

 Score = 31.6 bits (70), Expect = 2.6
 Identities = 27/121 (22%), Positives = 51/121 (42%), Gaps = 28/121 (23%)

Query: 81  ILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSM-------------------------- 114
           ++ FP+ V  S++ RT S++A   +   DVE +                           
Sbjct: 491 VMCFPKGVPRSQEARTESSQASDMMDTMDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGR 550

Query: 115 REDVYQRIVWLQEKVQKDSLRPEAARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLL 174
           ++D  ++ + L  KVQK   +    +   R +K  R+ G  +P++  ENI   + +L + 
Sbjct: 551 KKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKRGPRIPKD--ENINFKQSELPVT 608

Query: 175 C 175
           C
Sbjct: 609 C 609


>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
          Length = 532

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 26/102 (25%), Positives = 48/102 (47%), Gaps = 7/102 (6%)

Query: 30  AQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILDFPQHVS 89
           A Q+E   R  +E+ +R   +  ++EFE +  +    AL   E+    +       + V 
Sbjct: 266 APQVEAGKR--LEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREER-----RKVL 318

Query: 90  PSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQK 131
             ++ R    EAD+KL E + +  ++E++ +R     EK QK
Sbjct: 319 EEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQK 360


>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
          Length = 558

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 26/102 (25%), Positives = 48/102 (47%), Gaps = 7/102 (6%)

Query: 30  AQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILDFPQHVS 89
           A Q+E   R  +E+ +R   +  ++EFE +  +    AL   E+    +       + V 
Sbjct: 292 APQVEAGKR--LEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREER-----RKVL 344

Query: 90  PSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQK 131
             ++ R    EAD+KL E + +  ++E++ +R     EK QK
Sbjct: 345 EEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQK 386


>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
          Length = 564

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 26/102 (25%), Positives = 48/102 (47%), Gaps = 7/102 (6%)

Query: 30  AQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILDFPQHVS 89
           A Q+E   R  +E+ +R   +  ++EFE +  +    AL   E+    +       + V 
Sbjct: 298 APQVEAGKR--LEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREER-----RKVL 350

Query: 90  PSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQK 131
             ++ R    EAD+KL E + +  ++E++ +R     EK QK
Sbjct: 351 EEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQK 392


>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
          Length = 538

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 26/102 (25%), Positives = 48/102 (47%), Gaps = 7/102 (6%)

Query: 30  AQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILDFPQHVS 89
           A Q+E   R  +E+ +R   +  ++EFE +  +    AL   E+    +       + V 
Sbjct: 272 APQVEAGKR--LEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREER-----RKVL 324

Query: 90  PSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQK 131
             ++ R    EAD+KL E + +  ++E++ +R     EK QK
Sbjct: 325 EEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQK 366


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,963,383
Number of Sequences: 37866
Number of extensions: 1217444
Number of successful extensions: 3272
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 50
Number of HSP's that attempted gapping in prelim test: 3226
Number of HSP's gapped (non-prelim): 85
length of query: 689
length of database: 18,247,518
effective HSP length: 109
effective length of query: 580
effective length of database: 14,120,124
effective search space: 8189671920
effective search space used: 8189671920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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