Guide to the Human Genome
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Search of human proteins with 4507145

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507145 sorting nexin 4 [Homo sapiens]
         (450 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507145 sorting nexin 4 [Homo sapiens]                             907   0.0  
gi|153791707 sorting nexin family member 30 [Homo sapiens]            107   3e-23
gi|194294540 sorting nexin 7 isoform a [Homo sapiens]                  96   5e-20
gi|23111055 sorting nexin 7 isoform b [Homo sapiens]                   93   4e-19
gi|23111038 sorting nexin 2 [Homo sapiens]                             69   7e-12
gi|23943858 sorting nexin 8 [Homo sapiens]                             62   1e-09
gi|224177511 sorting nexin 18 isoform c [Homo sapiens]                 55   1e-07
gi|157057545 sorting nexin 18 isoform a [Homo sapiens]                 55   1e-07
gi|157057543 sorting nexin 18 isoform b [Homo sapiens]                 55   1e-07
gi|4507143 sorting nexin 3 isoform a [Homo sapiens]                    53   5e-07
gi|23111030 sorting nexin 12 [Homo sapiens]                            52   1e-06
gi|23111032 sorting nexin 1 isoform b [Homo sapiens]                   51   2e-06
gi|23111034 sorting nexin 1 isoform a [Homo sapiens]                   46   8e-05
gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [H...    45   1e-04
gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [H...    45   1e-04
gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [H...    45   1e-04
gi|23397574 sorting nexin 33 [Homo sapiens]                            45   1e-04
gi|23111026 sorting nexin 11 [Homo sapiens]                            44   4e-04
gi|23111028 sorting nexin 11 [Homo sapiens]                            44   4e-04
gi|23111041 sorting nexin 3 isoform b [Homo sapiens]                   43   7e-04
gi|23111023 sorting nexin 10 [Homo sapiens]                            43   7e-04
gi|23238244 sorting nexin 16 isoform a [Homo sapiens]                  42   0.001
gi|23238246 sorting nexin 16 isoform a [Homo sapiens]                  42   0.001
gi|31543452 PX domain containing serine/threonine kinase [Homo s...    42   0.001
gi|7706706 sorting nexin 9 [Homo sapiens]                              41   0.003
gi|23111036 sorting nexin 1 isoform c [Homo sapiens]                   40   0.004
gi|38708169 sorting nexin 25 [Homo sapiens]                            39   0.007
gi|154091028 sorting nexin 29 [Homo sapiens]                           37   0.037
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             37   0.048
gi|31563330 A-kinase anchor protein 13 isoform 1 [Homo sapiens]        37   0.048

>gi|4507145 sorting nexin 4 [Homo sapiens]
          Length = 450

 Score =  907 bits (2344), Expect = 0.0
 Identities = 450/450 (100%), Positives = 450/450 (100%)

Query: 1   MEQAPPDPERQLQPAPLEPLGSPDAGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEI 60
           MEQAPPDPERQLQPAPLEPLGSPDAGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEI
Sbjct: 1   MEQAPPDPERQLQPAPLEPLGSPDAGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEI 60

Query: 61  SVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVY 120
           SVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVY
Sbjct: 61  SVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVY 120

Query: 121 YPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLF 180
           YPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLF
Sbjct: 121 YPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLF 180

Query: 181 LTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQSVISHLLRV 240
           LTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQSVISHLLRV
Sbjct: 181 LTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQSVISHLLRV 240

Query: 241 RARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILEDEEHY 300
           RARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILEDEEHY
Sbjct: 241 RARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILEDEEHY 300

Query: 301 ADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTT 360
           ADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTT
Sbjct: 301 ADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTT 360

Query: 361 KLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKE 420
           KLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKE
Sbjct: 361 KLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKE 420

Query: 421 ALISYAVMQISMCKKGIQVWTNAKECFSKM 450
           ALISYAVMQISMCKKGIQVWTNAKECFSKM
Sbjct: 421 ALISYAVMQISMCKKGIQVWTNAKECFSKM 450


>gi|153791707 sorting nexin family member 30 [Homo sapiens]
          Length = 437

 Score =  107 bits (266), Expect = 3e-23
 Identities = 88/365 (24%), Positives = 163/365 (44%), Gaps = 49/365 (13%)

Query: 78  ETYTAYLIETRSVEHTDGQSVLTD-SLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEF 136
           ETY  Y I T+S   T  +  L + S+ RRY +F+ LRS L    P  ++PPLPEK   F
Sbjct: 106 ETYITYRITTKS---TRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLIPPLPEK---F 159

Query: 137 VWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNETGF 196
           V  K   D    +FVE RR  L+ FL RI  HP+L  ++ F +FLT +            
Sbjct: 160 VV-KGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFLTAKDLNAYKKQGIAL 218

Query: 197 QLKADSRLKALNATFRVKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHG 256
             +    +K +   ++++     F  +  Y D     +  + R+  R+            
Sbjct: 219 LTRMGESVKHVTGGYKLRTRPLEFAAIGDYLDTFALKLGTIDRIAQRIIKEEIEYLVELR 278

Query: 257 NYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALR 315
            YG V+S WSA+E E+ + L+     +   +++++++ +D  E +   L+EY+ Y+++++
Sbjct: 279 EYGPVYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDMTEDFLPVLREYILYSDSMK 338

Query: 316 AVCRKHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARI 375
           +V +K + +Q + E   + +A +K+   ++                           A +
Sbjct: 339 SVLKKRDQVQAEYEAKLEAVALRKEDRPKV--------------------------PADV 372

Query: 376 KVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKK 435
           +  ++++      LK              AD+ER++  K +D ++ L+  A   I   +K
Sbjct: 373 EKCQDRMECFNADLK--------------ADMERWQNNKRQDFRQLLMGMADKNIQYYEK 418

Query: 436 GIQVW 440
            +  W
Sbjct: 419 CLMAW 423


>gi|194294540 sorting nexin 7 isoform a [Homo sapiens]
          Length = 451

 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 95/391 (24%), Positives = 168/391 (42%), Gaps = 57/391 (14%)

Query: 55  LKKIEISVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLR 114
           LK + I+V E E       +   ET+  Y I T++       S     + RRY +F  L+
Sbjct: 93  LKDLFITVDEPESH-----VTTIETFITYRIITKTSRGEFDSSEF--EVRRRYQDFLWLK 145

Query: 115 SYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRD 174
             L   +P +++PPLPEK   F+  K   +  + DF+E RR  L  FL RIA HP L  +
Sbjct: 146 GKLEEAHPTLIIPPLPEK---FIV-KGMVERFNDDFIETRRKALHKFLNRIADHPTLTFN 201

Query: 175 KIFYLFLTQEGNWKETVNE---TGFQLKADSRLKALNATFR-VKNPDKRFTDLKHYSDEL 230
           + F +FLT +  W+ + ++    G   +    ++A+ ++ R VKN  + F ++ ++ +  
Sbjct: 202 EDFKIFLTAQA-WELSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELF 260

Query: 231 QSVISHLLRVRARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSI 290
              I+ + ++  R+       +     YG +   WSA E+++ D L+     +D    + 
Sbjct: 261 SQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKAT 320

Query: 291 DDILED-EEHYADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLASKKQQCEELVTGT 349
           +  +    E     + EY+ Y+E L  V ++ + +Q +L+   + L  KK   + L    
Sbjct: 321 EKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKADTDLL---- 376

Query: 350 VRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIER 409
                             PE+    I  LE+++      LK              AD ER
Sbjct: 377 ------------------PEE----IGKLEDKVECANNALK--------------ADWER 400

Query: 410 FKEQKNRDLKEALISYAVMQISMCKKGIQVW 440
           +K+    D+K A    A   I   ++ +  W
Sbjct: 401 WKQNMQNDIKLAFTDMAEENIHYYEQCLATW 431


>gi|23111055 sorting nexin 7 isoform b [Homo sapiens]
          Length = 336

 Score = 93.2 bits (230), Expect = 4e-19
 Identities = 76/290 (26%), Positives = 138/290 (47%), Gaps = 17/290 (5%)

Query: 55  LKKIEISVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLR 114
           LK + I+V E E       +   ET+  Y I T++       S     + RRY +F  L+
Sbjct: 29  LKDLFITVDEPESH-----VTTIETFITYRIITKTSRGEFDSSEF--EVRRRYQDFLWLK 81

Query: 115 SYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRD 174
             L   +P +++PPLPEK   F+  K   +  + DF+E RR  L  FL RIA HP L  +
Sbjct: 82  GKLEEAHPTLIIPPLPEK---FIV-KGMVERFNDDFIETRRKALHKFLNRIADHPTLTFN 137

Query: 175 KIFYLFLTQEGNWKETVNE---TGFQLKADSRLKALNATFR-VKNPDKRFTDLKHYSDEL 230
           + F +FLT +  W+ + ++    G   +    ++A+ ++ R VKN  + F ++ ++ +  
Sbjct: 138 EDFKIFLTAQA-WELSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELF 196

Query: 231 QSVISHLLRVRARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSI 290
              I+ + ++  R+       +     YG +   WSA E+++ D L+     +D    + 
Sbjct: 197 SQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKAT 256

Query: 291 DDILED-EEHYADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLASKK 339
           +  +    E     + EY+ Y+E L  V ++ + +Q +L+   + L  KK
Sbjct: 257 EKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKK 306


>gi|23111038 sorting nexin 2 [Homo sapiens]
          Length = 519

 Score = 69.3 bits (168), Expect = 7e-12
 Identities = 95/410 (23%), Positives = 163/410 (39%), Gaps = 70/410 (17%)

Query: 58  IEISVSEAEK-RTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSY 116
           IEI VS+ EK   G NA      Y AY + T++      +S    S+ RR+S+F  L S 
Sbjct: 142 IEIGVSDPEKVGDGMNA------YMAYRVTTKTSLSMFSKSEF--SVKRRFSDFLGLHSK 193

Query: 117 LLVYYPHI--VVPPLPEKRAEFVWHKL--SADNMDPDFVERRRIGLENFLLRIASHPILC 172
           L   Y H+  +VPP PEK    +        D+   +FVE+RR  LE +L R   HP L 
Sbjct: 194 LASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLL 253

Query: 173 RDKIFYLFLTQEGNWKETVNE-----TGFQLKADSRLKALN-ATFRVKNPDKRFTDLKHY 226
           +D     FL +       VN       G     +    A+N  T ++   D  F + +  
Sbjct: 254 QDPDLRQFL-ESSELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDAWFEEKQQQ 312

Query: 227 SDELQSVISHL-LRVRARVADR---------------LYGVYKVHGNYGRVFSEWSAIEK 270
            + L   +  L + V A V  R               + G  + H    R  S+ + +E+
Sbjct: 313 FENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEE 372

Query: 271 EMGDGLQSAGHHMDVYASSIDDILEDEEHYADQLKEYLFYAEALRAVCRKHELMQYDLEM 330
           ++ D L       D Y             +++ L +Y+    A++ V   H +  +    
Sbjct: 373 KI-DQLHQEQAFADFYM------------FSELLSDYIRLIAAVKGVF-DHRMKCWQKWE 418

Query: 331 AAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQLK 390
            AQ    KK++ E                 K+     P+    +I+  + +I E E +++
Sbjct: 419 DAQITLLKKREAE----------------AKMMVANKPD----KIQQAKNEIREWEAKVQ 458

Query: 391 SKNLEGREFVKNAWADIERFKEQKNRDLKEALISYAVMQISMCKKGIQVW 440
               +  +  K    ++ RF++++ +D K  +I Y    +   ++ I+ W
Sbjct: 459 QGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYW 508


>gi|23943858 sorting nexin 8 [Homo sapiens]
          Length = 465

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 62/255 (24%), Positives = 109/255 (42%), Gaps = 30/255 (11%)

Query: 88  RSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMD 147
           + VE+         S++RRY++F + +  LL  +P+ +VP LP KR       L AD   
Sbjct: 91  KHVEYEVSSQRFKSSVYRRYNDFVVFQEMLLHKFPYRMVPALPPKRM------LGADR-- 142

Query: 148 PDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNETGFQLKADSRLKAL 207
            +F+E RR  L+ F+  +A HP+   D +  LFL+  G+  +   +   Q   D  L   
Sbjct: 143 -EFIEARRRALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKLKESAQCVGDEFLNCK 201

Query: 208 NAT----FRVKNPDKRFTDLKHYSDELQSVISHLLRVRA-RVADR---------LYG-VY 252
            AT    F   +   +F   +     + +   H LR RA R+A R         ++G   
Sbjct: 202 LATRAKDFLPADIQAQFAISRELIRNIYNSF-HKLRDRAERIASRAIDNAADLLIFGKEL 260

Query: 253 KVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDIL-----EDEEHYADQLKEY 307
              G+       W+A+       L+ A   + V  + + D       ++E    ++L  +
Sbjct: 261 SAIGSDTTPLPSWAALNSSTWGSLKQALKGLSVEFALLADKAAQQGKQEENDVVEKLNLF 320

Query: 308 LFYAEALRAVCRKHE 322
           L   ++ + +C +HE
Sbjct: 321 LDLLQSYKDLCERHE 335


>gi|224177511 sorting nexin 18 isoform c [Homo sapiens]
          Length = 591

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 8/126 (6%)

Query: 105 RRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLR 164
           RRY  F+ L + L   +P I VP LPEK+A            + DF+ +RR GL  ++  
Sbjct: 311 RRYKHFDWLYARLAEKFPVISVPHLPEKQA--------TGRFEEDFISKRRKGLIWWMNH 362

Query: 165 IASHPILCRDKIFYLFLTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLK 224
           +ASHP+L +  +F  FLT   +  E   + G +      +   N    +  P     DL+
Sbjct: 363 MASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQ 422

Query: 225 HYSDEL 230
               ++
Sbjct: 423 EVESKI 428


>gi|157057545 sorting nexin 18 isoform a [Homo sapiens]
          Length = 624

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 8/126 (6%)

Query: 105 RRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLR 164
           RRY  F+ L + L   +P I VP LPEK+A            + DF+ +RR GL  ++  
Sbjct: 311 RRYKHFDWLYARLAEKFPVISVPHLPEKQA--------TGRFEEDFISKRRKGLIWWMNH 362

Query: 165 IASHPILCRDKIFYLFLTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLK 224
           +ASHP+L +  +F  FLT   +  E   + G +      +   N    +  P     DL+
Sbjct: 363 MASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQ 422

Query: 225 HYSDEL 230
               ++
Sbjct: 423 EVESKI 428


>gi|157057543 sorting nexin 18 isoform b [Homo sapiens]
          Length = 628

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 8/126 (6%)

Query: 105 RRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLR 164
           RRY  F+ L + L   +P I VP LPEK+A            + DF+ +RR GL  ++  
Sbjct: 311 RRYKHFDWLYARLAEKFPVISVPHLPEKQA--------TGRFEEDFISKRRKGLIWWMNH 362

Query: 165 IASHPILCRDKIFYLFLTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLK 224
           +ASHP+L +  +F  FLT   +  E   + G +      +   N    +  P     DL+
Sbjct: 363 MASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQ 422

Query: 225 HYSDEL 230
               ++
Sbjct: 423 EVESKI 428


>gi|4507143 sorting nexin 3 isoform a [Homo sapiens]
          Length = 162

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 32/81 (39%), Positives = 46/81 (56%), Gaps = 2/81 (2%)

Query: 105 RRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNM-DPDFVERRRIGLENFLL 163
           RRYS+FE LRS L      +VVPPLP K           D + D +F+E R+ GLE F+ 
Sbjct: 69  RRYSDFEWLRSEL-ERESKVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFIN 127

Query: 164 RIASHPILCRDKIFYLFLTQE 184
           ++A HP+   ++  ++FL  E
Sbjct: 128 KVAGHPLAQNERCLHMFLQDE 148


>gi|23111030 sorting nexin 12 [Homo sapiens]
          Length = 162

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 31/81 (38%), Positives = 47/81 (58%), Gaps = 2/81 (2%)

Query: 105 RRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNM-DPDFVERRRIGLENFLL 163
           RRYS+FE L++ L      IVVPPLP K  +        + + +  F+E RR GLE F+ 
Sbjct: 70  RRYSDFEWLKNEL-ERDSKIVVPPLPGKALKRQLPFRGDEGIFEESFIEERRQGLEQFIN 128

Query: 164 RIASHPILCRDKIFYLFLTQE 184
           +IA HP+   ++  ++FL +E
Sbjct: 129 KIAGHPLAQNERCLHMFLQEE 149


>gi|23111032 sorting nexin 1 isoform b [Homo sapiens]
          Length = 457

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 108/456 (23%), Positives = 170/456 (37%), Gaps = 84/456 (18%)

Query: 18  EPLGSPDAGL-----GAAVGKEAEGAGEESSGVDTMT-------HNNFWLKKIEISVSEA 65
           E L  P  GL     GAA G E E    ++ G D  T       H +  +    + ++  
Sbjct: 12  ERLPPPFPGLEPESEGAAGGSEPEAGDSDTEGEDIFTGAAVVSKHQSPKITTSLLPINNG 71

Query: 66  EKRTGRNAMNMQE-----------TYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLR 114
            K  G +    QE            Y AY + T++            ++ RR+S+F  L 
Sbjct: 72  SKENGIHEEQDQEPQDLFAGDGMNAYVAYKVTTQTSLPLFRSKQF--AVKRRFSDFLGLY 129

Query: 115 SYLLVYYPH--IVVPPLPEKRAEFVWHKL--SADNMDPDFVERRRIGLENFLLRIASHPI 170
             L   +     +VPP PEK    +        D+   +F+E+RR  LE +L RI +HP 
Sbjct: 130 EKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPT 189

Query: 171 LCRDKIFYLFLTQEGNWKETVNETGFQ-LKADSRLKALN-ATFRVKNPDKRFTDLK-HYS 227
           + +D     FL +E    E     G Q L     LK  N AT  V     +  +    + 
Sbjct: 190 MLQDPDVREFLEKE----ELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFE 245

Query: 228 DELQSVISHLLRVRARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYA 287
           ++LQ V     R+R     +L+ V +   N+ +   E +    +    L   G   D  A
Sbjct: 246 EKLQEVECEEQRLR-----KLHAVVETLVNHRK---ELALNTAQFAKSLAMLGSSEDNTA 297

Query: 288 SS--IDDILEDEE-----HYADQLKEYLFYAEALRAVCRKHELMQYDLEMAAQDLASKKQ 340
            S  +  + E EE     H      ++   AE L    R   +++     AA D   K  
Sbjct: 298 LSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVR-----AAFDQRMKTW 352

Query: 341 QCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFV 400
           Q  +    T++                 ++REA  ++L     +  QQ K + LE    V
Sbjct: 353 QRWQDAQATLQ-----------------KKREAEARLLWANKPDKLQQAKDEILEWESRV 395

Query: 401 KNAWADIE-----------RFKEQKNRDLKEALISY 425
                D E           RF+++K++D K  +I Y
Sbjct: 396 TQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKY 431


>gi|23111034 sorting nexin 1 isoform a [Homo sapiens]
          Length = 522

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 85/346 (24%), Positives = 134/346 (38%), Gaps = 59/346 (17%)

Query: 105 RRYSEFELLRSYLLVYYPH--IVVPPLPEKRAEFVWHKL--SADNMDPDFVERRRIGLEN 160
           RR+S+F  L   L   +     +VPP PEK    +        D+   +F+E+RR  LE 
Sbjct: 185 RRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALER 244

Query: 161 FLLRIASHPILCRDKIFYLFLTQEGNWKETVNETGFQ-LKADSRLKALN-ATFRVKNPDK 218
           +L RI +HP + +D     FL +E    E     G Q L     LK  N AT  V     
Sbjct: 245 YLQRIVNHPTMLQDPDVREFLEKE----ELPRAVGTQTLSGAGLLKMFNKATDAVSKMTI 300

Query: 219 RFTDLK-HYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGRVFSEWSAIEKEMGDGLQ 277
           +  +    + ++LQ V     R+R     +L+ V +   N+ +   E +    +    L 
Sbjct: 301 KMNESDIWFEEKLQEVECEEQRLR-----KLHAVVETLVNHRK---ELALNTAQFAKSLA 352

Query: 278 SAGHHMDVYASS--IDDILEDEE-----HYADQLKEYLFYAEALRAVCRKHELMQYDLEM 330
             G   D  A S  +  + E EE     H      ++   AE L    R   +++     
Sbjct: 353 MLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVR----- 407

Query: 331 AAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQLK 390
           AA D   K  Q  +    T++                 ++REA  ++L     +  QQ K
Sbjct: 408 AAFDQRMKTWQRWQDAQATLQ-----------------KKREAEARLLWANKPDKLQQAK 450

Query: 391 SKNLEGREFVKNAWADIE-----------RFKEQKNRDLKEALISY 425
            + LE    V     D E           RF+++K++D K  +I Y
Sbjct: 451 DEILEWESRVTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKY 496


>gi|31563383 serum/glucocorticoid regulated kinase 3 isoform 2 [Homo
           sapiens]
          Length = 464

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 24/69 (34%), Positives = 40/69 (57%), Gaps = 8/69 (11%)

Query: 103 LWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFL 162
           ++RRY+EF+ L + L   +P + +  +P KR       +  DN DPDF+++RR GL  F+
Sbjct: 47  VFRRYAEFDKLYNTLKKQFPAMALK-IPAKR-------IFGDNFDPDFIKQRRAGLNEFI 98

Query: 163 LRIASHPIL 171
             +  +P L
Sbjct: 99  QNLVRYPEL 107


>gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
           sapiens]
          Length = 496

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 24/69 (34%), Positives = 40/69 (57%), Gaps = 8/69 (11%)

Query: 103 LWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFL 162
           ++RRY+EF+ L + L   +P + +  +P KR       +  DN DPDF+++RR GL  F+
Sbjct: 47  VFRRYAEFDKLYNTLKKQFPAMALK-IPAKR-------IFGDNFDPDFIKQRRAGLNEFI 98

Query: 163 LRIASHPIL 171
             +  +P L
Sbjct: 99  QNLVRYPEL 107


>gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
           sapiens]
          Length = 496

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 24/69 (34%), Positives = 40/69 (57%), Gaps = 8/69 (11%)

Query: 103 LWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFL 162
           ++RRY+EF+ L + L   +P + +  +P KR       +  DN DPDF+++RR GL  F+
Sbjct: 47  VFRRYAEFDKLYNTLKKQFPAMALK-IPAKR-------IFGDNFDPDFIKQRRAGLNEFI 98

Query: 163 LRIASHPIL 171
             +  +P L
Sbjct: 99  QNLVRYPEL 107


>gi|23397574 sorting nexin 33 [Homo sapiens]
          Length = 574

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 10/88 (11%)

Query: 103 LWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFL 162
           ++RRY  F+ L + LL  +  I VP LPEK+A            + DF+E+R+  L  ++
Sbjct: 263 VYRRYKHFDWLYNRLLHKFTVISVPHLPEKQA--------TGRFEEDFIEKRKRRLILWM 314

Query: 163 LRIASHPILCRDKIFYLFLT--QEGNWK 188
             + SHP+L + + F  FL+   +  WK
Sbjct: 315 DHMTSHPVLSQYEGFQHFLSCLDDKQWK 342


>gi|23111026 sorting nexin 11 [Homo sapiens]
          Length = 270

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 30/95 (31%), Positives = 45/95 (47%), Gaps = 10/95 (10%)

Query: 92  HTDGQSVL--TDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPD 149
           HT+ ++    T  + RRY EF  LR  L      + VP LP K   F            +
Sbjct: 43  HTNSKAFTAKTSCVRRRYREFVWLRKQLQRNAGLVPVPELPGKSTFF--------GTSDE 94

Query: 150 FVERRRIGLENFLLRIASHPILCRDKIFYLFLTQE 184
           F+E+RR GL++FL ++    +L  D   +LFL  +
Sbjct: 95  FIEKRRQGLQHFLEKVLQSVVLLSDSQLHLFLQSQ 129


>gi|23111028 sorting nexin 11 [Homo sapiens]
          Length = 270

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 30/95 (31%), Positives = 45/95 (47%), Gaps = 10/95 (10%)

Query: 92  HTDGQSVL--TDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPD 149
           HT+ ++    T  + RRY EF  LR  L      + VP LP K   F            +
Sbjct: 43  HTNSKAFTAKTSCVRRRYREFVWLRKQLQRNAGLVPVPELPGKSTFF--------GTSDE 94

Query: 150 FVERRRIGLENFLLRIASHPILCRDKIFYLFLTQE 184
           F+E+RR GL++FL ++    +L  D   +LFL  +
Sbjct: 95  FIEKRRQGLQHFLEKVLQSVVLLSDSQLHLFLQSQ 129


>gi|23111041 sorting nexin 3 isoform b [Homo sapiens]
          Length = 130

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 22/62 (35%), Positives = 35/62 (56%), Gaps = 1/62 (1%)

Query: 124 IVVPPLPEKRAEFVWHKLSADNM-DPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLT 182
           +VVPPLP K           D + D +F+E R+ GLE F+ ++A HP+   ++  ++FL 
Sbjct: 55  VVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNERCLHMFLQ 114

Query: 183 QE 184
            E
Sbjct: 115 DE 116


>gi|23111023 sorting nexin 10 [Homo sapiens]
          Length = 201

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 41/154 (26%), Positives = 72/154 (46%), Gaps = 17/154 (11%)

Query: 92  HTDGQ--SVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDP- 148
           HT+    ++ T  + RRY EF  LR  L      + +P LP K   F        NM+  
Sbjct: 37  HTNSMCFTMKTSCVRRRYREFVWLRQRLQSNALLVQLPELPSKNLFF--------NMNNR 88

Query: 149 DFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKE----TVNETGFQL-KADSR 203
             V++RR GLE+FL ++  + +L  D   +LFL    N ++       +T + + +A  +
Sbjct: 89  QHVDQRRQGLEDFLRKVLQNALLLSDSSLHLFLQSHLNSEDIEACVSGQTKYSVEEAIHK 148

Query: 204 LKALNATFRVKNPD-KRFTDLKHYSDELQSVISH 236
              +N  F  ++ + K+  D+ + S+   S + H
Sbjct: 149 FALMNRRFPEEDEEGKKENDIDYDSESSSSGLGH 182


>gi|23238244 sorting nexin 16 isoform a [Homo sapiens]
          Length = 344

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 42/144 (29%), Positives = 67/144 (46%), Gaps = 26/144 (18%)

Query: 70  GRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPL 129
           G   M  +  +T Y I    V+ T  +S +   ++RRY++F  L   L   +P   +  L
Sbjct: 114 GYEVMEERAKFTVYKI---LVKKTPEESWV---VFRRYTDFSRLNDKLKEMFPGFRLA-L 166

Query: 130 PEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASH----------PILCRDKIFYL 179
           P KR    W K   DN + DF+E R++GL+ FL  + +H            LC D     
Sbjct: 167 PPKR----WFK---DNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGP 219

Query: 180 F--LTQEGNWKETVNETGFQLKAD 201
           F  L +   + ET+ ET ++L+ +
Sbjct: 220 FDSLEESRAFCETLEETNYRLQKE 243


>gi|23238246 sorting nexin 16 isoform a [Homo sapiens]
          Length = 344

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 42/144 (29%), Positives = 67/144 (46%), Gaps = 26/144 (18%)

Query: 70  GRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPL 129
           G   M  +  +T Y I    V+ T  +S +   ++RRY++F  L   L   +P   +  L
Sbjct: 114 GYEVMEERAKFTVYKI---LVKKTPEESWV---VFRRYTDFSRLNDKLKEMFPGFRLA-L 166

Query: 130 PEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIASH----------PILCRDKIFYL 179
           P KR    W K   DN + DF+E R++GL+ FL  + +H            LC D     
Sbjct: 167 PPKR----WFK---DNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGP 219

Query: 180 F--LTQEGNWKETVNETGFQLKAD 201
           F  L +   + ET+ ET ++L+ +
Sbjct: 220 FDSLEESRAFCETLEETNYRLQKE 243


>gi|31543452 PX domain containing serine/threonine kinase [Homo
           sapiens]
          Length = 578

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 32/123 (26%), Positives = 57/123 (46%), Gaps = 22/123 (17%)

Query: 78  ETYTAYLIETRSVEHTDGQSVLTDSLW---RRYSEFELLRSYLLVYYPHIVVPPLPEKRA 134
           +++T Y+I  +       + +  ++ W   RRYS+F+LL + L +    + +PP      
Sbjct: 31  QSHTEYIIRVQ-------RGISVENSWQIVRRYSDFDLLNNSLQIAGLSLPLPP------ 77

Query: 135 EFVWHKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET 194
                K    NMD +F+  R+ GL+N+L  I ++ IL   ++   FL    N+     E 
Sbjct: 78  -----KKLIGNMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFL-DPNNYSANYTEI 131

Query: 195 GFQ 197
             Q
Sbjct: 132 ALQ 134


>gi|7706706 sorting nexin 9 [Homo sapiens]
          Length = 595

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 48/221 (21%), Positives = 88/221 (39%), Gaps = 36/221 (16%)

Query: 102 SLWRRYSEFELLRSYLLVYYPHIV-VPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLEN 160
           S+  RY  F+ L   LLV +   + +P LP+K+             + +F++ R   L+ 
Sbjct: 282 SVNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQV--------TGRFEEEFIKMRMERLQA 333

Query: 161 FLLRIASHPILCRDKIFYLFLT--QEGNWKETVNETGFQLKADSRLKALNATFRVKNPDK 218
           ++ R+  HP++   ++F  FL    E  WK     TG + KA+    A    F    P+ 
Sbjct: 334 WMTRMCRHPVISESEVFQQFLNFRDEKEWK-----TG-KRKAERDELAGVMIFSTMEPEA 387

Query: 219 RFTDLKHYSDELQSV----------ISHLLRVRARVADRLYG-VYKVHGNYGRVFSEWSA 267
              DL     + ++V          +  LL V      R  G + K +   G+     + 
Sbjct: 388 PDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGPLPKEYQKIGKALQSLAT 447

Query: 268 I--------EKEMGDGLQSAGHHMDVYASSIDDILEDEEHY 300
           +        E ++ D +  AG   +  AS + +  + + H+
Sbjct: 448 VFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHF 488


>gi|23111036 sorting nexin 1 isoform c [Homo sapiens]
          Length = 474

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 28/84 (33%), Positives = 42/84 (50%), Gaps = 4/84 (4%)

Query: 105 RRYSEFELLRSYLLVYYPH--IVVPPLPEKRAEFVWHKL--SADNMDPDFVERRRIGLEN 160
           RR+S+F  L   L   +     +VPP PEK    +        D+   +F+E+RR  LE 
Sbjct: 185 RRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALER 244

Query: 161 FLLRIASHPILCRDKIFYLFLTQE 184
           +L RI +HP + +D     FL +E
Sbjct: 245 YLQRIVNHPTMLQDPDVREFLEKE 268


>gi|38708169 sorting nexin 25 [Homo sapiens]
          Length = 840

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 41/187 (21%), Positives = 76/187 (40%), Gaps = 13/187 (6%)

Query: 48  MTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYLIETRSVEHTDGQSVLTDSLWRRY 107
           M   ++W + +   + +A   +G       E    Y +   S++   G      ++ RR 
Sbjct: 497 MARTDWWCENL--GMWKASITSGEVTEENGEQLPCYFVMV-SLQEVGGVETKNWTVPRRL 553

Query: 108 SEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLRIAS 167
           SEF+ L   L    P +    LP         KL   ++D  F+E+ +  L  FL  + S
Sbjct: 554 SEFQNLHRKLSECVPSLKKVQLPSLS------KLPFKSIDQKFMEKSKNQLNKFLQNLLS 607

Query: 168 HPILCRDKIFYLFLTQEGNWKETVNETGFQ--LKADSRLKALNATF--RVKNPDKRFTDL 223
              LC+ +  Y FL+   ++ + ++  G +      S L+ L   F    +   +  +DL
Sbjct: 608 DERLCQSEALYAFLSPSPDYLKVIDVQGKKNSFSLSSFLERLPRDFFSHQEEETEEDSDL 667

Query: 224 KHYSDEL 230
             Y D++
Sbjct: 668 SDYGDDV 674


>gi|154091028 sorting nexin 29 [Homo sapiens]
          Length = 428

 Score = 37.0 bits (84), Expect = 0.037
 Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 8/69 (11%)

Query: 102 SLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENF 161
           +++RRY+EF  L   L   YP +     P K+A          N D  FVE RR  L+N+
Sbjct: 305 NIYRRYTEFRSLHHKLQNKYPQVRAYNFPPKKA--------IGNKDAKFVEERRKQLQNY 356

Query: 162 LLRIASHPI 170
           L  + +  I
Sbjct: 357 LRSVMNKVI 365


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 36.6 bits (83), Expect = 0.048
 Identities = 56/291 (19%), Positives = 120/291 (41%), Gaps = 36/291 (12%)

Query: 139 HKLSADNMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNETGFQL 198
           HK + +N+     E++        LR A   +L  +       +Q    KE V++   Q+
Sbjct: 591 HKQAQENLHDQVQEQKAH------LRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQI 644

Query: 199 KADSRLKALNATFRVKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNY 258
           KA + L  L +    K   +   DL+++ D  Q+ +           D+   + K+    
Sbjct: 645 KAKTEL--LLSAEAAKTAQR--ADLQNHLDTAQNALQ----------DKQQELNKITTQL 690

Query: 259 GRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILEDEEHYADQLKEYLFYAEALRAVC 318
            +V ++    ++E    L+S   H+  Y      + +  E    Q+K+    A++L    
Sbjct: 691 DQVTAKLQD-KQEHCSQLES---HLKEYKEKYLSLEQKTEELEGQIKK--LEADSLEVKA 744

Query: 319 RKHELMQ---------YDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPE 369
            K + +Q          DLE+ A +L+ + +  +E+V+ T      K    +   Q+  +
Sbjct: 745 SKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTK 804

Query: 370 QREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNRDLKE 420
           Q E + ++L++      Q+ K ++ E    ++    ++++ K +K   + E
Sbjct: 805 QEEEK-QILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTE 854



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 44/201 (21%), Positives = 84/201 (41%), Gaps = 31/201 (15%)

Query: 256 GNYGRVFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILEDEEHYADQLKEYLFYAEALR 315
           G+   +F  + A+     D       ++ +    +  + ++ +     LKE  +Y+E L+
Sbjct: 51  GSADELFKHYEAVHDAGNDSGHGGESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEELK 110

Query: 316 AVCRKHELMQYD-------LEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETP 368
               K++ +Q         +  ++ +L S +QQ EE  T     F++K M      ++  
Sbjct: 111 KELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQT---ENFNIKQM------KDLF 161

Query: 369 EQREARIKVLEEQINEGEQQLKSKNLEGREFVKNAWADIERFKEQKNR------DLKEAL 422
           EQ+ A       Q+      +KSK  E R   + A   + R  E+ N+      DLK  L
Sbjct: 162 EQKAA-------QLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTEL 214

Query: 423 ISY-AVMQISMCKKG-IQVWT 441
           +    +  +++ KK  +QV T
Sbjct: 215 LQRPGIEDVAVLKKELVQVQT 235


>gi|31563330 A-kinase anchor protein 13 isoform 1 [Homo sapiens]
          Length = 2817

 Score = 36.6 bits (83), Expect = 0.048
 Identities = 32/135 (23%), Positives = 62/135 (45%), Gaps = 11/135 (8%)

Query: 282  HMDVYASSIDDILEDEEHYADQLKEYLFYAEALRAVCRKHELMQYD----LEMAAQDLAS 337
            H+    S++  ++  ++ Y +  K  L      R++ R   L++ +    LE   QDLA+
Sbjct: 2531 HLYELLSALQGVVLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQRQDLAN 2590

Query: 338  -KKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEG 396
             +KQQ + L     R    +    +L       +REA +   EE++ +G+Q L+ +  E 
Sbjct: 2591 LQKQQAQYLEEKRRREREWEAREREL------REREALLAQREEEVQQGQQDLEKEREEL 2644

Query: 397  REFVKNAWADIERFK 411
            ++       D+ER +
Sbjct: 2645 QQKKGTYQYDLERLR 2659


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,806,750
Number of Sequences: 37866
Number of extensions: 732368
Number of successful extensions: 3534
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 97
Number of HSP's that attempted gapping in prelim test: 3280
Number of HSP's gapped (non-prelim): 335
length of query: 450
length of database: 18,247,518
effective HSP length: 106
effective length of query: 344
effective length of database: 14,233,722
effective search space: 4896400368
effective search space used: 4896400368
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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