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Search of human proteins with 4506153
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506153 prostasin preproprotein [Homo sapiens]
(343 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506153 prostasin preproprotein [Homo sapiens] 711 0.0
gi|117956391 protease, serine, 33 [Homo sapiens] 257 1e-68
gi|13994276 marapsin [Homo sapiens] 238 8e-63
gi|11545839 protease, serine, 22 [Homo sapiens] 233 2e-61
gi|58218970 protease, serine, 36 [Homo sapiens] 224 1e-58
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 220 1e-57
gi|21614531 testisin isoform 2 [Homo sapiens] 215 4e-56
gi|205360905 testis-specific serine protease 1 [Homo sapiens] 213 2e-55
gi|5803197 testisin isoform 1 [Homo sapiens] 213 2e-55
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 207 8e-54
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] 204 7e-53
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 203 2e-52
gi|68508970 tryptase beta 2 precursor [Homo sapiens] 202 5e-52
gi|187761337 transmembrane protease, serine 11B [Homo sapiens] 199 2e-51
gi|148806900 epidermis-specific serine protease-like protein [Ho... 199 3e-51
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 196 2e-50
gi|223942069 enterokinase precursor [Homo sapiens] 194 7e-50
gi|4503627 coagulation factor XI precursor [Homo sapiens] 194 7e-50
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 194 1e-49
gi|33695155 hepsin [Homo sapiens] 194 1e-49
gi|4504481 hepsin [Homo sapiens] 194 1e-49
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 193 2e-49
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 188 5e-48
gi|4758508 transmembrane protease, serine 11D [Homo sapiens] 186 3e-47
gi|34098976 marapsin 2 [Homo sapiens] 185 4e-47
gi|4504383 HGF activator preproprotein [Homo sapiens] 185 6e-47
gi|11415040 matriptase [Homo sapiens] 183 2e-46
gi|21614533 testisin isoform 3 [Homo sapiens] 182 5e-46
gi|222831592 transmembrane protease, serine 7 [Homo sapiens] 180 2e-45
gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo ... 179 3e-45
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 711 bits (1835), Expect = 0.0
Identities = 343/343 (100%), Positives = 343/343 (100%)
Query: 1 MAQKGVLGPGQLGAVAILLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQV 60
MAQKGVLGPGQLGAVAILLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQV
Sbjct: 1 MAQKGVLGPGQLGAVAILLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQV 60
Query: 61 SITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDI 120
SITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDI
Sbjct: 61 SITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDI 120
Query: 121 IPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSV 180
IPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSV
Sbjct: 121 IPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSV 180
Query: 181 SLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGG 240
SLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGG
Sbjct: 181 SLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGG 240
Query: 241 PLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQESQ 300
PLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQESQ
Sbjct: 241 PLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQESQ 300
Query: 301 PDSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSPWLSEH 343
PDSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSPWLSEH
Sbjct: 301 PDSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSPWLSEH 343
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 257 bits (656), Expect = 1e-68
Identities = 128/275 (46%), Positives = 170/275 (61%), Gaps = 7/275 (2%)
Query: 15 VAILLYLGLLRSGTGAEGAE-APCGVAPQA-RITGGSSAVAGQWPWQVSITYEGVHVCGG 72
V +LL LG G +G + A CG + RI GG G+WPWQ SI + G HVCGG
Sbjct: 9 VLLLLVLG----AAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGG 64
Query: 73 SLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQ 132
SL++ QWVL+AAHCFP Y V+LGA +L S S ++ ++ P Y ++G++
Sbjct: 65 SLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGAR 124
Query: 133 GDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLE 192
GD+ALLQL RP+ S ++P+CLP A P G C VTGWG + P V L +PLQ +
Sbjct: 125 GDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVR 184
Query: 193 VPLISRETCNCLYNIDAK-PEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWY 251
VPL+ TC+ LY++ A P+ V +CAGY +G KDACQGDSGGPL+C G W
Sbjct: 185 VPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWV 244
Query: 252 LTGIVSWGDACGARNRPGVYTLASSYASWIQSKVT 286
L G+VSWG C NRPGVYT ++Y+ WIQ++V+
Sbjct: 245 LVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVS 279
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 238 bits (606), Expect = 8e-63
Identities = 119/278 (42%), Positives = 164/278 (58%), Gaps = 5/278 (1%)
Query: 14 AVAILLYLGLLRSGTGAEGAEAPCGVAPQA-RITGGSSAVAGQWPWQVSITYEGVHVCGG 72
AV +LL LL G+ A CG R+ GG G+WPWQVSI G H CGG
Sbjct: 6 AVPLLL---LLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGG 62
Query: 73 SLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQ 132
SL++EQWVL+AAHCF + Y+V LGA QL A + ++ + +P Y S
Sbjct: 63 SLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASS 122
Query: 133 GDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLE 192
D+AL++L P+ F+ YI P+CLP + F G++C VTGWG + L P+ LQ+L
Sbjct: 123 ADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLA 182
Query: 193 VPLISRETCNCLYNIDAK-PEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWY 251
VP+I CN LY+ D + +P ++ DM+CAG+ EG KDAC+GDSGGPL C V W
Sbjct: 183 VPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWL 242
Query: 252 LTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQ 289
G++SWG+ C +NRPGVY +++ +WI + +LQ
Sbjct: 243 QAGVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPKLQ 280
>gi|11545839 protease, serine, 22 [Homo sapiens]
Length = 317
Score = 233 bits (594), Expect = 2e-61
Identities = 128/292 (43%), Positives = 169/292 (57%), Gaps = 13/292 (4%)
Query: 7 LGPGQLGAVAILLYLGLLRSGTGAEGAEAP----CGVAPQA-RITGGSSAVAGQWPWQVS 61
LG G LG LL LL S A P CG Q R+ GG + +WPW VS
Sbjct: 10 LGGGCLGTFTSLL---LLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVS 66
Query: 62 ITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKE-AYEVKLGAHQLDSYSEDAKVSTLKDI 120
I G H C GSL++ +WV++AAHCF +K + V LGA QL + ++ + +
Sbjct: 67 IQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWV 126
Query: 121 IPHPSYL-QEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPS 179
PHP Y +EG+ DIAL++L R I FS + PICLP A+ P HC ++GWG +
Sbjct: 127 EPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDG 186
Query: 180 VSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSG 239
V L P+ LQ+L+VP+I E C+ LY A + EDM+CAGY+EG +DAC GDSG
Sbjct: 187 VPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGP---ITEDMLCAGYLEGERDACLGDSG 243
Query: 240 GPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPR 291
GPL C V+G W L GI+SWG+ C RNRPGVY S++ SW++ V +Q R
Sbjct: 244 GPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLR 295
>gi|58218970 protease, serine, 36 [Homo sapiens]
Length = 855
Score = 224 bits (570), Expect = 1e-58
Identities = 119/283 (42%), Positives = 160/283 (56%), Gaps = 6/283 (2%)
Query: 26 SGTGAEGAEAPCG-VAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAA 84
S T E + CG P ARI GGS+A G WPWQVS+ + G H+CGGSL++ WVLSAA
Sbjct: 27 SPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAA 86
Query: 85 HCFPSEHHKEA---YEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLS 141
HCF + E + V LG H D + A + I+ +Y Q D+ALL+L+
Sbjct: 87 HCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLA 146
Query: 142 RPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETC 201
P + + P+CLP A+ F +G C TGWG V + L P LQ++E+ L+ TC
Sbjct: 147 SPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATC 206
Query: 202 NCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDA 261
CLY+ + M+CAGY EG +D CQGDSGGPL C G W+ GI S+G
Sbjct: 207 QCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFG 266
Query: 262 CGARNRPGVYTLASSYASWIQSKV--TELQPRVVPQTQESQPD 302
CG RNRPGV+T ++Y +WI+ +V +E P Q Q++Q D
Sbjct: 267 CGRRNRPGVFTAVATYEAWIREQVMGSEPGPAFPTQPQKTQSD 309
Score = 107 bits (266), Expect = 2e-23
Identities = 88/319 (27%), Positives = 135/319 (42%), Gaps = 50/319 (15%)
Query: 37 CGVAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAY 96
CG AP+ G WPW+ + G C G+LVSE WVL+ A CF + ++
Sbjct: 325 CGKAPRP----------GAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSP 374
Query: 97 EVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLP 156
L A ++ S + + ++ H + + + D+ALLQL P+ S RP+CLP
Sbjct: 375 PRDLDAWRVLLPSR-PRAERVARLVQHENASWDNA-SDLALLQLRTPVNLSAASRPVCLP 432
Query: 157 AANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYN-----IDAKP 211
F G C + WG P++ P LE L+ C+CLY +
Sbjct: 433 HPEHYFLPGSRCRLARWGRGEPALG-----PGALLEAELLGGWWCHCLYGRQGAAVPLPG 487
Query: 212 EEPHFVQEDMVCAGYVEGGK-DACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGV 270
+ PH +C Y E + +C DS L C EG W+L GI + C RP
Sbjct: 488 DPPH-----ALCPAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGC---LRPRA 539
Query: 271 YTLASSYASWIQSKVTE---LQPRVV----PQTQESQPDSNLCGSHLAFSSAPAQGLLRP 323
+ ++ WI S VT L+ ++ P +E+ ++ C H + + P
Sbjct: 540 FFPLQTHGPWI-SHVTRGAYLEDQLAWDWGPDGEET--ETQTCPPHTEHGACGLRLEAAP 596
Query: 324 ILFLPLGLALGLLSPWLSE 342
+ G+L PWL+E
Sbjct: 597 V---------GVLWPWLAE 606
Score = 90.5 bits (223), Expect = 2e-18
Identities = 80/265 (30%), Positives = 107/265 (40%), Gaps = 34/265 (12%)
Query: 56 WPWQVSITYEGVHVCGGSLVSEQWVLSAAHCF--PSEHHKEAYEVKLGAHQLDSYSEDAK 113
WPW + G VC G L++ WVL+A HC P EV LG S + +
Sbjct: 601 WPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQ 660
Query: 114 VSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGW 173
VS L I P +L G + +ALL+LS + S PICL A P G C V GW
Sbjct: 661 VSRLVISIRLPQHL--GLRPPLALLELSSRVEPSPSALPICLHP--AGIPPGASCWVLGW 716
Query: 174 GHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDA 233
V + V ++++ C+CLY P +C Y EG ++
Sbjct: 717 KEPQDRVPVAA-------AVSILTQRICDCLYQGILPP--------GTLCVLYAEGQENR 761
Query: 234 CQGDSGGPLSCPV-EGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTE---LQ 289
C+ S PL C + EG W L G+ G ++ +WI V E L
Sbjct: 762 CEMTSAPPLLCQMTEGSWILVGMAVQGSR-------ELFAAIGPEEAWISQTVGEANFLP 814
Query: 290 PRVVPQTQESQPDSNLCGSHLAFSS 314
P P SNLC LA +S
Sbjct: 815 PSGSPHWPTG--GSNLCPPELAKAS 837
>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
Length = 321
Score = 220 bits (561), Expect = 1e-57
Identities = 124/281 (44%), Positives = 159/281 (56%), Gaps = 19/281 (6%)
Query: 12 LGAVAILLYLGLLRSGTGAEGAEAPCGVAPQA-----RITGGSSAVAGQWPWQVSITYEG 66
LGA +LL L + G + CG PQ RI GG +A AG WPWQ S+
Sbjct: 3 LGACGLLLLLAV--PGVSLRTLQPGCG-RPQVSDAGGRIVGGHAAPAGAWPWQASLRLRR 59
Query: 67 VHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSY 126
VHVCGGSL+S QWVL+AAHCF + Y+V LG ++ + ST++ II H S
Sbjct: 60 VHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGELEI---TLSPHFSTVRQIILHSSP 116
Query: 127 L-QEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTP 185
Q G+ GDIAL++LS P+T S I P+CLP A+ F G+ C VTGWG+ L P
Sbjct: 117 SGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPP 176
Query: 186 KPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCP 245
L++++V ++ ETC D +Q DM+CA G DACQ DSGGPL C
Sbjct: 177 YSLREVKVSVVDTETCRR----DYPGPGGSILQPDMLCA---RGPGDACQDDSGGPLVCQ 229
Query: 246 VEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVT 286
V G W GIVSWG+ CG NRPGVYT +Y +WI+ +T
Sbjct: 230 VNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHIT 270
>gi|21614531 testisin isoform 2 [Homo sapiens]
Length = 312
Score = 215 bits (548), Expect = 4e-56
Identities = 137/337 (40%), Positives = 182/337 (54%), Gaps = 45/337 (13%)
Query: 16 AILLYLGLLRSGTGA-EGAEA-----PCGVAP-QARITGGSSAVAGQWPWQVSITYEGVH 68
A+LL L L R+G E EA PCG +RI GG A G+WPWQ S+ H
Sbjct: 6 ALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSH 65
Query: 69 VCGGSLVSEQWVLSAAHCFPSE-HHKEAYEVKLGAHQLDSYSEDAKVST------LKDII 121
VCG SL+S +W L+AAHCF ++ + V+ G QL S + + +I
Sbjct: 66 VCGVSLLSHRWALTAAHCFETDLSDPSGWMVQFG--QLTSMPSFWSLQAYYTRYFVSNIY 123
Query: 122 PHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVS 181
P YL S DIAL++LS P+T++++I+PICL A+ F N C VTGWG++ +
Sbjct: 124 LSPRYLGN-SPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEA 182
Query: 182 LLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGP 241
L +P LQ+++V +I+ CN L+ K + DMVCAG +GGKDAC GDSGGP
Sbjct: 183 LPSPHTLQEVQVAIINNSMCNHLF---LKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGP 239
Query: 242 LSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQESQP 301
L+C GLWY G+VSWG CG NRPGVYT S + WIQ +++ Q+ SQP
Sbjct: 240 LACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQ--------KLMAQSGMSQP 291
Query: 302 DSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSP 338
D + P+LF PL AL LL P
Sbjct: 292 DPSW-----------------PLLFFPLLWALPLLGP 311
>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
Length = 318
Score = 213 bits (542), Expect = 2e-55
Identities = 123/309 (39%), Positives = 173/309 (55%), Gaps = 31/309 (10%)
Query: 1 MAQKGVLGPGQLGAVAILLYLGLLRSGTGAE------GAEAPCGVAP-QARITGGSSAVA 53
+A+ G+ PG+LGA L++G GA G E CG A + GG +
Sbjct: 13 LARAGLGKPGELGA---------LQAGPGAARRPGGGGREEACGHREIHALVAGGVESAR 63
Query: 54 GQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGA-------HQLD 106
G+WPWQ S+ H CGGSL+S +WVLSAAHCF ++ + V+LG L
Sbjct: 64 GRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGELTSRPTPWNLR 123
Query: 107 SYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGL 166
+YS KV +DII +P L + DIALL+L+ +T++ YI+PIC+ ++ +F +
Sbjct: 124 AYSSRYKV---QDIIVNPDALGV-LRNDIALLRLASSVTYNAYIQPICIESSTFNFVHRP 179
Query: 167 HCTVTGWGHVAPSVSLLTPK-PLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAG 225
C VTGWG ++PS + L P L++ +V +++ CN L+ +P + + M CAG
Sbjct: 180 DCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFE---QPSSRSMIWDSMFCAG 236
Query: 226 YVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKV 285
+G D C+GDSGGPL C +GLWY GIVSWG CG NRPGVYT S Y WI+ +
Sbjct: 237 AEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWIRRVM 296
Query: 286 TELQPRVVP 294
+ PR P
Sbjct: 297 SHSTPRPNP 305
>gi|5803197 testisin isoform 1 [Homo sapiens]
Length = 314
Score = 213 bits (542), Expect = 2e-55
Identities = 137/339 (40%), Positives = 181/339 (53%), Gaps = 47/339 (13%)
Query: 16 AILLYLGLLRSGTGA-EGAEA-----PCGVAP-QARITGGSSAVAGQWPWQVSITYEGVH 68
A+LL L L R+G E EA PCG +RI GG A G+WPWQ S+ H
Sbjct: 6 ALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSH 65
Query: 69 VCGGSLVSEQWVLSAAHCFPSEHH---KEAYEVKLGAHQLDSYSEDAKVST------LKD 119
VCG SL+S +W L+AAHCF + + V+ G QL S + + +
Sbjct: 66 VCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFG--QLTSMPSFWSLQAYYTRYFVSN 123
Query: 120 IIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPS 179
I P YL S DIAL++LS P+T++++I+PICL A+ F N C VTGWG++
Sbjct: 124 IYLSPRYLGN-SPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKED 182
Query: 180 VSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSG 239
+L +P LQ+++V +I+ CN L+ K + DMVCAG +GGKDAC GDSG
Sbjct: 183 EALPSPHTLQEVQVAIINNSMCNHLF---LKYSFRKDIFGDMVCAGNAQGGKDACFGDSG 239
Query: 240 GPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQES 299
GPL+C GLWY G+VSWG CG NRPGVYT S + WIQ +++ Q+ S
Sbjct: 240 GPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQ--------KLMAQSGMS 291
Query: 300 QPDSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSP 338
QPD + P+LF PL AL LL P
Sbjct: 292 QPDPSW-----------------PLLFFPLLWALPLLGP 313
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 207 bits (528), Expect = 8e-54
Identities = 101/256 (39%), Positives = 145/256 (56%), Gaps = 12/256 (4%)
Query: 32 GAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEGV---HVCGGSLVSEQWVLSAAHCFP 88
G + C RI GG+++ G+WPWQVS+ + H+CGGSL+ QWVL+AAHCF
Sbjct: 378 GDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD 437
Query: 89 SEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSR 148
++ + + G L ++D S +K+II H +Y DIAL++L P+ ++
Sbjct: 438 GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTE 497
Query: 149 YIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNID 208
+ +PICLP+ + +C VTGWG + LQ++ +PL++ E C Y
Sbjct: 498 FQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEI--QNILQKVNIPLVTNEECQKRY--- 552
Query: 209 AKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRP 268
+ + + + MVCAGY EGGKDAC+GDSGGPL C G+W L GI SWG+ C R +P
Sbjct: 553 ----QDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQP 608
Query: 269 GVYTLASSYASWIQSK 284
GVYT + Y WI K
Sbjct: 609 GVYTKVAEYMDWILEK 624
>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
Length = 275
Score = 204 bits (520), Expect = 7e-53
Identities = 111/273 (40%), Positives = 151/273 (55%), Gaps = 10/273 (3%)
Query: 18 LLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEG---VHVCGGSL 74
LL L L + A A AP + I GG A +WPWQVS+ G +H CGGSL
Sbjct: 4 LLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSL 63
Query: 75 VSEQWVLSAAHCF-PSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQG 133
+ QWVL+AAHC P A V+L L Y +D ++ + II HP +
Sbjct: 64 IHPQWVLTAAHCVGPDVKDLAALRVQLREQHL--YYQD-QLLPVSRIIVHPQFYTAQIGA 120
Query: 134 DIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEV 193
DIALL+L P+ S ++ + LP A+ +FP G+ C VTGWG V L P PL+Q++V
Sbjct: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180
Query: 194 PLISRETCNCLYNIDA-KPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYL 252
P++ C+ Y++ A ++ V++DM+CAG +D+CQGDSGGPL C V G W
Sbjct: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQ 238
Query: 253 TGIVSWGDACGARNRPGVYTLASSYASWIQSKV 285
G+VSWG+ C NRPG+YT + Y WI V
Sbjct: 239 AGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYV 271
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 203 bits (516), Expect = 2e-52
Identities = 104/262 (39%), Positives = 150/262 (57%), Gaps = 14/262 (5%)
Query: 29 GAEGAEAPCGV-APQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCF 87
G++ CG+ P +RI GG+ + G+WPWQ S+ G H+CGG+L++++WV++AAHCF
Sbjct: 560 GSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCF 619
Query: 88 PSEHHKEA--YEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPIT 145
+ + V LG +S + ++ HP + ++ D+ALLQL P+
Sbjct: 620 QEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVV 679
Query: 146 FSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLY 205
S +RP+CLPA + F GLHC +TGWG + + LQ+++V LI ++ C+ +Y
Sbjct: 680 RSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPI--SNALQKVDVQLIPQDLCSEVY 737
Query: 206 NIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSC-PVEGLWYLTGIVSWGDACGA 264
P M+CAGY +G KDACQGDSGGPL C + G W+L G+VSWG CG
Sbjct: 738 RYQVTPR--------MLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGR 789
Query: 265 RNRPGVYTLASSYASWIQSKVT 286
N GVYT + SWIQ VT
Sbjct: 790 PNYFGVYTRITGVISWIQQVVT 811
>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
Length = 275
Score = 202 bits (513), Expect = 5e-52
Identities = 110/273 (40%), Positives = 150/273 (54%), Gaps = 10/273 (3%)
Query: 18 LLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEG---VHVCGGSL 74
LL L L + A A AP + I GG A +WPWQVS+ +H CGGSL
Sbjct: 4 LLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSL 63
Query: 75 VSEQWVLSAAHCF-PSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQG 133
+ QWVL+AAHC P A V+L L Y +D ++ + II HP +
Sbjct: 64 IHPQWVLTAAHCVGPDVKDLAALRVQLREQHL--YYQD-QLLPVSRIIVHPQFYTAQIGA 120
Query: 134 DIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEV 193
DIALL+L P+ S ++ + LP A+ +FP G+ C VTGWG V L P PL+Q++V
Sbjct: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180
Query: 194 PLISRETCNCLYNIDA-KPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYL 252
P++ C+ Y++ A ++ V++DM+CAG +D+CQGDSGGPL C V G W
Sbjct: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQ 238
Query: 253 TGIVSWGDACGARNRPGVYTLASSYASWIQSKV 285
G+VSWG+ C NRPG+YT + Y WI V
Sbjct: 239 AGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYV 271
>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
Length = 416
Score = 199 bits (507), Expect = 2e-51
Identities = 101/242 (41%), Positives = 142/242 (58%), Gaps = 13/242 (5%)
Query: 44 RITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAH 103
+I G S++ G WPWQ S+ ++G H CG SL+S +W+LSAAHCF +++ + + V G
Sbjct: 184 KIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNFGIV 243
Query: 104 QLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFP 163
Y +++II H +Y G DIAL+QL+ ++F+ YIR ICLP A
Sbjct: 244 VNKPY----MTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLS 299
Query: 164 NGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVC 223
+ VTGWG + + S P LQ+ + +I + CN Y FV + M+C
Sbjct: 300 ENDNVVVTGWGTLYMNGSF--PVILQEDFLKIIDNKICNASYAYSG------FVTDTMLC 351
Query: 224 AGYVEGGKDACQGDSGGPLSCP-VEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQ 282
AG++ G DACQ DSGGPL+ P +W+L GIVSWGD CG +N+PGVYT +SY +WI
Sbjct: 352 AGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWIT 411
Query: 283 SK 284
SK
Sbjct: 412 SK 413
>gi|148806900 epidermis-specific serine protease-like protein [Homo
sapiens]
Length = 328
Score = 199 bits (506), Expect = 3e-51
Identities = 106/247 (42%), Positives = 146/247 (59%), Gaps = 8/247 (3%)
Query: 43 ARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGA 102
+R+ GG A AG+WPWQVS+ ++ +CGGSLVSE+ +L+AAHC +Y V LG+
Sbjct: 26 SRVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLILTAAHCIQPTWTTFSYTVWLGS 85
Query: 103 HQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASF 162
+ + K K +I HP Y + + D+ALL+LS +TF+ I PICLP+
Sbjct: 86 ITVGDSRKRVKYYVSKIVI-HPKY--QDTTADVALLKLSSQVTFTSAILPICLPSVTKQL 142
Query: 163 PNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYN---IDAKPEEPHFVQE 219
C VTGWG V S LQ+ EVP+I R+ C LYN I EP ++E
Sbjct: 143 AIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLYNPIGIFLPALEP-VIKE 201
Query: 220 DMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYAS 279
D +CAG + KD+C+GDSGGPLSC ++G+W TG+VSWG CG ++ PGVYT Y
Sbjct: 202 DKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVVSWGLECG-KSLPGVYTNVIYYQK 260
Query: 280 WIQSKVT 286
WI + ++
Sbjct: 261 WINATIS 267
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 196 bits (499), Expect = 2e-50
Identities = 103/252 (40%), Positives = 145/252 (57%), Gaps = 13/252 (5%)
Query: 37 CGV-APQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHK-- 93
CG+ A RI GG+ A +WPWQVS+ + H+CGG+L+ QWVL+AAHCF K
Sbjct: 317 CGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVL 376
Query: 94 EAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPI 153
E ++V G L E A ++ +II + +Y E DIAL++LS+P+T S +I P
Sbjct: 377 EGWKVYAGTSNLHQLPEAASIA---EIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPA 433
Query: 154 CLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEE 213
CLP +F C +TG+G + +P L++++V LI + CN D+
Sbjct: 434 CLPMHGQTFSLNETCWITGFGKTRETDDKTSPF-LREVQVNLIDFKKCNDYLVYDS---- 488
Query: 214 PHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTL 273
++ M+CAG + GG+D+CQGDSGGPL C WYL G+ SWG CG RN+PGVYT
Sbjct: 489 --YLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTK 546
Query: 274 ASSYASWIQSKV 285
+ WI SK+
Sbjct: 547 VTEVLPWIYSKM 558
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 194 bits (494), Expect = 7e-50
Identities = 101/242 (41%), Positives = 138/242 (57%), Gaps = 11/242 (4%)
Query: 44 RITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEA-YEVKLGA 102
+I GGS+A G WPW V + Y G +CG SLVS W++SAAHC + + + + LG
Sbjct: 784 KIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGL 843
Query: 103 HQLDSYSEDAKVSTLKD-IIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANAS 161
H + + V L D I+ +P Y + DIA++ L + ++ YI+PICLP N
Sbjct: 844 HMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQV 903
Query: 162 FPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDM 221
FP G +C++ GWG V + T LQ+ +VPL+S E C PE + + E+M
Sbjct: 904 FPPGRNCSIAGWGTVVYQGT--TANILQEADVPLLSNERCQ-----QQMPE--YNITENM 954
Query: 222 VCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWI 281
+CAGY EGG D+CQGDSGGPL C W+L G+ S+G C NRPGVY S + WI
Sbjct: 955 ICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWI 1014
Query: 282 QS 283
QS
Sbjct: 1015 QS 1016
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 194 bits (494), Expect = 7e-50
Identities = 100/251 (39%), Positives = 134/251 (53%), Gaps = 12/251 (4%)
Query: 37 CGVAPQARITGGSSAVAGQWPWQVSITYEGV---HVCGGSLVSEQWVLSAAHCFPSEHHK 93
C + RI GG+++V G+WPWQV++ H+CGGS++ QW+L+AAHCF
Sbjct: 380 CTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESP 439
Query: 94 EAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPI 153
+ V G ED +++II H Y S DIALL+L + ++ RPI
Sbjct: 440 KILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPI 499
Query: 154 CLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEE 213
CLP+ C VTGWG+ + LQ+ ++PL++ E C Y
Sbjct: 500 CLPSKGDRNVIYTDCWVTGWGYRKLRDKI--QNTLQKAKIPLVTNEECQKRYR------- 550
Query: 214 PHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTL 273
H + M+CAGY EGGKDAC+GDSGGPLSC +W+L GI SWG+ C R RPGVYT
Sbjct: 551 GHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTN 610
Query: 274 ASSYASWIQSK 284
Y WI K
Sbjct: 611 VVEYVDWILEK 621
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 194 bits (493), Expect = 1e-49
Identities = 102/249 (40%), Positives = 135/249 (54%), Gaps = 13/249 (5%)
Query: 37 CGVAPQA-RITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEA 95
CG P A RI GG S G+WPWQ S+ H CGGS+++ +WV++AAHC S
Sbjct: 209 CGARPLASRIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLARL 268
Query: 96 YEVKLGAHQLD-SYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPIC 154
++ A + S + + ++ IIPHP Y + D+ALL+L + FS + +C
Sbjct: 269 SSWRVHAGLVSHSAVRPHQGALVERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVC 328
Query: 155 LPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCN--CLYNIDAKPE 212
LPA FP G C V+GWGH PS + + LQ VPL S + CN C+Y+ P
Sbjct: 329 LPAKEQHFPKGSRCWVSGWGHTHPSHTYSSDM-LQDTVVPLFSTQLCNSSCVYSGALTPR 387
Query: 213 EPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYT 272
M+CAGY++G DACQGDSGGPL CP W L G+VSWG C N PGVY
Sbjct: 388 --------MLCAGYLDGRADACQGDSGGPLVCPDGDTWRLVGVVSWGRGCAEPNHPGVYA 439
Query: 273 LASSYASWI 281
+ + WI
Sbjct: 440 KVAEFLDWI 448
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 194 bits (492), Expect = 1e-49
Identities = 107/253 (42%), Positives = 137/253 (54%), Gaps = 23/253 (9%)
Query: 41 PQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKL 100
P RI GG G+WPWQVS+ Y+G H+CGGSL+S WVL+AAHCFP E ++ ++
Sbjct: 159 PVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFP-ERNRVLSRWRV 217
Query: 101 GAHQLDSYSEDAKVSTLKDIIPHPSYL------QEGSQGDIALLQLSRPITFSRYIRPIC 154
A + S ++ ++ H YL E + DIAL+ LS P+ + YI+P+C
Sbjct: 218 FAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVC 277
Query: 155 LPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCN--CLYNIDAKPE 212
LPAA + +G CTVTGWG+ LQ+ VP+IS + CN Y KP+
Sbjct: 278 LPAAGQALVDGKICTVTGWGNT--QYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPK 335
Query: 213 EPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVE----GLWYLTGIVSWGDACGARNRP 268
M CAGY EGG DACQGDSGGP C W L GIVSWG C +P
Sbjct: 336 --------MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKP 387
Query: 269 GVYTLASSYASWI 281
GVYT S + WI
Sbjct: 388 GVYTKVSDFREWI 400
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 194 bits (492), Expect = 1e-49
Identities = 107/253 (42%), Positives = 137/253 (54%), Gaps = 23/253 (9%)
Query: 41 PQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKL 100
P RI GG G+WPWQVS+ Y+G H+CGGSL+S WVL+AAHCFP E ++ ++
Sbjct: 159 PVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFP-ERNRVLSRWRV 217
Query: 101 GAHQLDSYSEDAKVSTLKDIIPHPSYL------QEGSQGDIALLQLSRPITFSRYIRPIC 154
A + S ++ ++ H YL E + DIAL+ LS P+ + YI+P+C
Sbjct: 218 FAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVC 277
Query: 155 LPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCN--CLYNIDAKPE 212
LPAA + +G CTVTGWG+ LQ+ VP+IS + CN Y KP+
Sbjct: 278 LPAAGQALVDGKICTVTGWGNT--QYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPK 335
Query: 213 EPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVE----GLWYLTGIVSWGDACGARNRP 268
M CAGY EGG DACQGDSGGP C W L GIVSWG C +P
Sbjct: 336 --------MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKP 387
Query: 269 GVYTLASSYASWI 281
GVYT S + WI
Sbjct: 388 GVYTKVSDFREWI 400
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 193 bits (491), Expect = 2e-49
Identities = 98/271 (36%), Positives = 145/271 (53%), Gaps = 14/271 (5%)
Query: 29 GAEGAEAPCGVAPQ----ARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAA 84
G++ A CG+ P RI GG A G++PWQ S+ H CG ++++ +W++SAA
Sbjct: 183 GSDEAHCECGLQPAWRMAGRIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAA 242
Query: 85 HCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPI 144
HCF + +GA L + + I+ HP Y + + D+A+L+L+ P+
Sbjct: 243 HCFNEFQDPTKWVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPL 302
Query: 145 TFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCL 204
F R+I+P+CLPAA FP C ++GWG++ L+ P+ LQ+ V L+ + C L
Sbjct: 303 PFGRHIQPVCLPAATHIFPPSKKCLISGWGYLKEDF-LVKPEVLQKATVELLDQALCASL 361
Query: 205 YNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSC-PVEGLWYLTGIVSWGDACG 263
Y H + + MVCAGY++G D+CQGDSGGPL C G ++L GIVSWG C
Sbjct: 362 YG--------HSLTDRMVCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCA 413
Query: 264 ARNRPGVYTLASSYASWIQSKVTELQPRVVP 294
RPGVY + WI T+ + P
Sbjct: 414 EARRPGVYARVTRLRDWILEATTKASMPLAP 444
Score = 189 bits (480), Expect = 3e-48
Identities = 104/255 (40%), Positives = 141/255 (55%), Gaps = 16/255 (6%)
Query: 37 CGVAPQA--RITGGSSAVAGQWPWQVSITYEG-VHVCGGSLVSEQWVLSAAHCFPSEHHK 93
CG+AP A RI GGS+A G+WPWQVS+ H CG LV+E+W+LSAAHCF
Sbjct: 817 CGLAPAALTRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDP 876
Query: 94 EAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPI 153
+ + LG L + ++ + I HP Y D+ALL+L+ P+ SR +RPI
Sbjct: 877 KQWAAFLGTPFLSG--AEGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPI 934
Query: 154 CLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEE 213
CLP P+G C +TGWG V S+ + LQ+ V L+S +TC Y
Sbjct: 935 CLPEPAPRPPDGTRCVITGWGSVREGGSM--ARQLQKAAVRLLSEQTCRRFY-------- 984
Query: 214 PHFVQEDMVCAGYVEGGKDACQGDSGGPLSC-PVEGLWYLTGIVSWGDACGARNRPGVYT 272
P + M+CAG+ +GG D+C GD+GGPL+C G W LTG+ SWG CG + PGVYT
Sbjct: 985 PVQISSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYT 1044
Query: 273 LASSYASWIQSKVTE 287
++ WI + E
Sbjct: 1045 RVAAVRGWIGQHIQE 1059
Score = 188 bits (478), Expect = 5e-48
Identities = 98/252 (38%), Positives = 144/252 (57%), Gaps = 19/252 (7%)
Query: 37 CGVAPQ----ARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHH 92
CG P R+ GG A +G+ PWQVS+ H CG ++V ++W+LSAAHCF +H
Sbjct: 492 CGARPAMEKPTRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCF---NH 548
Query: 93 KEAYEVK--LGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYI 150
+ +V+ LG L L+ ++ HP Y D+A+L+L+ P+ F++YI
Sbjct: 549 TKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYI 608
Query: 151 RPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAK 210
+P+CLP A FP G C ++GWG+ + P+ LQ+ V +I ++TC+ LYN
Sbjct: 609 QPVCLPLAIQKFPVGRKCMISGWGNTQEG-NATKPELLQKASVGIIDQKTCSVLYNFS-- 665
Query: 211 PEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSC-PVEGLWYLTGIVSWGDACGARNRPG 269
+ + M+CAG++EG D+CQGDSGGPL+C G++YL GIVSWG C +PG
Sbjct: 666 ------LTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPG 719
Query: 270 VYTLASSYASWI 281
VYT + WI
Sbjct: 720 VYTRITRLKGWI 731
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 188 bits (478), Expect = 5e-48
Identities = 90/243 (37%), Positives = 139/243 (57%), Gaps = 9/243 (3%)
Query: 43 ARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGA 102
+RI GG+ ++ QWPWQ S+ ++G H+CGGS+++ W+++AAHC + +++ +++G
Sbjct: 215 SRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLPKSWTIQVGL 274
Query: 103 HQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASF 162
L A ++ I+ H Y + DIAL++L+ P+TF+ I+P+CLP + +F
Sbjct: 275 VSL--LDNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENF 332
Query: 163 PNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMV 222
P+G C +GWG +P L VPLIS + CN + + M+
Sbjct: 333 PDGKVCWTSGWGATEDGAGDASPV-LNHAAVPLISNKICN------HRDVYGGIISPSML 385
Query: 223 CAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQ 282
CAGY+ GG D+CQGDSGGPL C LW L G S+G C N+PGVYT +S+ WI
Sbjct: 386 CAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIH 445
Query: 283 SKV 285
++
Sbjct: 446 EQM 448
>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
Length = 418
Score = 186 bits (471), Expect = 3e-47
Identities = 99/255 (38%), Positives = 141/255 (55%), Gaps = 19/255 (7%)
Query: 37 CGVAP------QARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSE 90
CG P + RI GG+ A G WPWQVS+ H CGGSL++ W+L+AAHCF S
Sbjct: 173 CGAGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSN 232
Query: 91 HHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYI 150
+ + G S + +++I+ H +Y + DIAL++L +TF++ I
Sbjct: 233 SNPRDWIATSGI----STTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDI 288
Query: 151 RPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAK 210
+CLPAA + P G VTGWG A + T L+Q +V +IS + CN ++ +
Sbjct: 289 HSVCLPAATQNIPPGSTAYVTGWG--AQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGA 346
Query: 211 PEEPHFVQEDMVCAGYVEGGKDACQGDSGGPL-SCPVEGLWYLTGIVSWGDACGARNRPG 269
+ M+CAG +GG DACQGDSGGPL LW++ GIVSWGD CG ++PG
Sbjct: 347 ------ILSGMLCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPG 400
Query: 270 VYTLASSYASWIQSK 284
VYT ++Y WI+ +
Sbjct: 401 VYTRVTAYLDWIRQQ 415
>gi|34098976 marapsin 2 [Homo sapiens]
Length = 326
Score = 185 bits (470), Expect = 4e-47
Identities = 106/298 (35%), Positives = 152/298 (51%), Gaps = 22/298 (7%)
Query: 5 GVLGPGQLGAVAILLYLGLLR-----------SGTGAEGAEAPCGVAPQARITGGSSAVA 53
G LGP LG + +LL + R G G+ A + + +I GG A
Sbjct: 9 GPLGPSALGLLLLLLVVAPPRVAALVHRQPENQGISLTGSVACGRPSMEGKILGGVPAPE 68
Query: 54 GQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAK 113
+WPWQVS+ Y G+HVCGGS+++E WVLSAAHCF + + + Y++ +G L +
Sbjct: 69 RKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNHTQ 128
Query: 114 VSTLKDIIPHPSY-LQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTG 172
+ +I HP+Y + GD+AL+QL I FS + P+CL + + +C TG
Sbjct: 129 WYEVNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNLTSA-NCWATG 187
Query: 173 WGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKD 232
WG V+ T LQ++++PLI C+ LY ++ DM+CAG + K
Sbjct: 188 WGLVSKQGE--TSDELQEMQLPLILEPWCHLLYG------HMSYIMPDMLCAGDILNAKT 239
Query: 233 ACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQP 290
C+GDSGGPL C W GIVSWG C PGVY S ++ WI + E+ P
Sbjct: 240 VCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWICDNI-EITP 296
>gi|4504383 HGF activator preproprotein [Homo sapiens]
Length = 655
Score = 185 bits (469), Expect = 6e-47
Identities = 100/258 (38%), Positives = 147/258 (56%), Gaps = 17/258 (6%)
Query: 44 RITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAH 103
RI GGSS++ G PW +I Y G C GSLV WV+SAAHCF +++ V LG H
Sbjct: 407 RIIGGSSSLPGSHPWLAAI-YIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQH 465
Query: 104 QLDSYSEDAKVSTLKDIIPHPSY-LQEGSQGDIALLQLS----RPITFSRYIRPICLPAA 158
+ ++ + ++ IP+ Y + S D+ L++L R T S++++PICLP
Sbjct: 466 FFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEP 525
Query: 159 NASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNC--LYNIDAKPEEPHF 216
++FP G C + GWGH+ +VS + L++ VPL++ C+ +Y D P
Sbjct: 526 GSTFPAGHKCQIAGWGHLDENVSGYSSS-LREALVPLVADHKCSSPEVYGADISP----- 579
Query: 217 VQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASS 276
+M+CAGY + DACQGDSGGPL+C G+ YL GI+SWGD CG ++PGVYT ++
Sbjct: 580 ---NMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVAN 636
Query: 277 YASWIQSKVTELQPRVVP 294
Y WI ++ + V P
Sbjct: 637 YVDWINDRIRPPRRLVAP 654
>gi|11415040 matriptase [Homo sapiens]
Length = 855
Score = 183 bits (464), Expect = 2e-46
Identities = 105/267 (39%), Positives = 147/267 (55%), Gaps = 25/267 (9%)
Query: 29 GAEGAEAPCGVAP---QARITGGSSAVAGQWPWQVSITYEGV-HVCGGSLVSEQWVLSAA 84
G++ + CG+ QAR+ GG+ A G+WPWQVS+ G H+CG SL+S W++SAA
Sbjct: 596 GSDEKDCDCGLRSFTRQARVVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAA 655
Query: 85 HCFPSEH-----HKEAYEVKLGAH-QLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALL 138
HC+ + + LG H Q + + LK II HP + DIALL
Sbjct: 656 HCYIDDRGFRYSDPTQWTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALL 715
Query: 139 QLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHV--APSVSLLTPKPLQQLEVPLI 196
+L +P +S +RPICLP A+ FP G VTGWGH + +L+ LQ+ E+ +I
Sbjct: 716 ELEKPAEYSSMVRPICLPDASHVFPAGKAIWVTGWGHTQYGGTGALI----LQKGEIRVI 771
Query: 197 SRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPL-SCPVEGLWYLTGI 255
++ TC L P + M+C G++ GG D+CQGDSGGPL S +G + G+
Sbjct: 772 NQTTCENLL--------PQQITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGV 823
Query: 256 VSWGDACGARNRPGVYTLASSYASWIQ 282
VSWGD C RN+PGVYT + WI+
Sbjct: 824 VSWGDGCAQRNKPGVYTRLPLFRDWIK 850
>gi|21614533 testisin isoform 3 [Homo sapiens]
Length = 300
Score = 182 bits (461), Expect = 5e-46
Identities = 127/339 (37%), Positives = 170/339 (50%), Gaps = 61/339 (17%)
Query: 16 AILLYLGLLRSGTGA-EGAEA-----PCGVAP-QARITGGSSAVAGQWPWQVSITYEGVH 68
A+LL L L R+G E EA PCG +RI GG A G+WPWQ S+ H
Sbjct: 6 ALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSH 65
Query: 69 VCGGSLVSEQWVLSAAHCFPSEHH---KEAYEVKLGAHQLDSYSEDAKVST------LKD 119
VCG SL+S +W L+AAHCF + + V+ G QL S + + +
Sbjct: 66 VCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFG--QLTSMPSFWSLQAYYTRYFVSN 123
Query: 120 IIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPS 179
I P YL S DIAL++LS P+T++++I+PICL A+ F N C VTGWG++
Sbjct: 124 IYLSPRYLGN-SPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKED 182
Query: 180 VSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSG 239
+L +P LQ+++V +I+ CN L+ K + DM GDSG
Sbjct: 183 EALPSPHTLQEVQVAIINNSMCNHLF---LKYSFRKDIFGDM--------------GDSG 225
Query: 240 GPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQES 299
GPL+C GLWY G+VSWG CG NRPGVYT S + WIQ +++ Q+ S
Sbjct: 226 GPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQ--------KLMAQSGMS 277
Query: 300 QPDSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSP 338
QPD + P+LF PL AL LL P
Sbjct: 278 QPDPSW-----------------PLLFFPLLWALPLLGP 299
>gi|222831592 transmembrane protease, serine 7 [Homo sapiens]
Length = 717
Score = 180 bits (456), Expect = 2e-45
Identities = 111/270 (41%), Positives = 142/270 (52%), Gaps = 23/270 (8%)
Query: 27 GTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHC 86
G+ EG + RI GG+ + G WPWQVS+ + G CG S++S +W+LSAAHC
Sbjct: 462 GSDEEGCTCSRSSSALHRIIGGTDTLEGGWPWQVSLHFVGSAYCGASVISREWLLSAAHC 521
Query: 87 FPSEHHKEAYEVKLGAHQLDSYSE-DAK-VSTLKDIIPHPSYLQEGSQGDIALLQLS--R 142
F H + L Y + +AK VS ++ I+ H Y + DIALLQLS
Sbjct: 522 F---HGNRLSDPTPWTAHLGMYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIALLQLSIAW 578
Query: 143 PITFSRYIRPICLPAANASFPNGLHCTVTGWG--HVAPSVSLLTPKPLQQLEVPLISRET 200
P T + I+PIC+P +G C VTGWG H A + L LQQ EV LI +
Sbjct: 579 PETLKQLIQPICIPPTGQRVRSGEKCWVTGWGRRHEADNKGSLV---LQQAEVELIDQTL 635
Query: 201 CNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSC--PVEGLWYLTGIVSW 258
C Y I + M+CAG + G +DAC+GDSGGPLSC +G W LTGIVSW
Sbjct: 636 CVSTYGI---------ITSRMLCAGIMSGKRDACKGDSGGPLSCRRKSDGKWILTGIVSW 686
Query: 259 GDACGARNRPGVYTLASSYASWIQSKVTEL 288
G G N PGVYT S++ WI V L
Sbjct: 687 GHGSGRPNFPGVYTRVSNFVPWIHKYVPSL 716
>gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo
sapiens]
Length = 418
Score = 179 bits (454), Expect = 3e-45
Identities = 105/268 (39%), Positives = 144/268 (53%), Gaps = 21/268 (7%)
Query: 24 LRSGTGAEGAEAPCG--VAPQA--RITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQW 79
+ S TG +A CG V P RI G A WPWQ S+ Y+ +H CG +L+S W
Sbjct: 162 MSSSTGELTVQASCGKRVVPLNVNRIASGVIAPKAAWPWQASLQYDNIHQCGATLISNTW 221
Query: 80 VLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQ 139
+++AAHCF + + V G + ++ I H Y + DIA++Q
Sbjct: 222 LVTAAHCFQKYKNPHQWTVSFGT----KINPPLMKRNVRRFIIHEKYRSAAREYDIAVVQ 277
Query: 140 LSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRE 199
+S +TFS IR ICLP A+ASF L +TG+G A + L++ V +IS +
Sbjct: 278 VSSRVTFSDDIRQICLPEASASFQPNLTVHITGFG--ALYYGGESQNDLREARVKIISDD 335
Query: 200 TCN--CLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPL-SCPVEGLWYLTGIV 256
C +Y D KP M CAGY+EG DAC+GDSGGPL + ++ WYL GIV
Sbjct: 336 VCKQPQVYGNDIKP--------GMFCAGYMEGIYDACRGDSGGPLVTRDLKDTWYLIGIV 387
Query: 257 SWGDACGARNRPGVYTLASSYASWIQSK 284
SWGD CG +++PGVYT + Y +WI SK
Sbjct: 388 SWGDNCGQKDKPGVYTQVTYYRNWIASK 415
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,175,724
Number of Sequences: 37866
Number of extensions: 758773
Number of successful extensions: 2502
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 166
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 1816
Number of HSP's gapped (non-prelim): 209
length of query: 343
length of database: 18,247,518
effective HSP length: 103
effective length of query: 240
effective length of database: 14,347,320
effective search space: 3443356800
effective search space used: 3443356800
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.