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Search of human proteins with 4505873
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505873 phospholipase D1 isoform a [Homo sapiens]
(1074 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505873 phospholipase D1 isoform a [Homo sapiens] 2194 0.0
gi|194272176 phospholipase D1 isoform b [Homo sapiens] 2090 0.0
gi|156564407 phospholipase D2 [Homo sapiens] 548 e-155
gi|7661880 centaurin beta1 [Homo sapiens] 35 0.50
gi|22748711 hypothetical protein LOC122046 [Homo sapiens] 33 1.1
gi|50428933 C1q domain containing 1 isoform 1 [Homo sapiens] 33 1.4
gi|23503235 C1q domain containing 1 isoform 2 [Homo sapiens] 33 1.4
gi|32698730 nuclear fragile X mental retardation protein interac... 33 1.4
gi|238908495 similar to pleckstrin homology domain protein (5V32... 32 2.5
gi|154355004 strawberry notch homolog 2 isoform 2 [Homo sapiens] 32 3.2
gi|154355002 strawberry notch homolog 2 isoform 1 [Homo sapiens] 32 3.2
gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens] 32 3.2
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 32 4.2
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 32 4.2
gi|73747844 ligase III, DNA, ATP-dependent isoform beta precurso... 31 5.5
gi|73747829 ligase III, DNA, ATP-dependent isoform alpha precurs... 31 5.5
gi|24797143 sorting nexin 14 isoform b [Homo sapiens] 30 9.4
gi|24797145 sorting nexin 14 isoform a [Homo sapiens] 30 9.4
gi|21735548 centrosomal protein 2 [Homo sapiens] 30 9.4
gi|31742501 sorting nexin family member 27 [Homo sapiens] 30 9.4
>gi|4505873 phospholipase D1 isoform a [Homo sapiens]
Length = 1074
Score = 2194 bits (5686), Expect = 0.0
Identities = 1074/1074 (100%), Positives = 1074/1074 (100%)
Query: 1 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA 60
MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
Sbjct: 1 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA 60
Query: 61 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF 120
IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
Sbjct: 61 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF 120
Query: 121 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR 180
KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
Sbjct: 121 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR 180
Query: 181 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC 240
KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
Sbjct: 181 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC 240
Query: 241 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID 300
CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
Sbjct: 241 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID 300
Query: 301 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG 360
NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
Sbjct: 301 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG 360
Query: 361 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY 420
YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
Sbjct: 361 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY 420
Query: 421 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI 480
KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
Sbjct: 421 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI 480
Query: 481 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS 540
DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
Sbjct: 481 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS 540
Query: 541 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGL 600
IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGL
Sbjct: 541 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGL 600
Query: 601 KPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL 660
KPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL
Sbjct: 601 KPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL 660
Query: 661 DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL 720
DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL
Sbjct: 661 DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL 720
Query: 721 PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE 780
PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE
Sbjct: 721 PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE 780
Query: 781 NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ 840
NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ
Sbjct: 781 NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ 840
Query: 841 AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL 900
AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL
Sbjct: 841 AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL 900
Query: 901 IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF 960
IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF
Sbjct: 901 IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF 960
Query: 961 RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI 1020
RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI
Sbjct: 961 RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI 1020
Query: 1021 NKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT 1074
NKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT
Sbjct: 1021 NKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT 1074
>gi|194272176 phospholipase D1 isoform b [Homo sapiens]
Length = 1036
Score = 2090 bits (5415), Expect = 0.0
Identities = 1035/1074 (96%), Positives = 1036/1074 (96%), Gaps = 38/1074 (3%)
Query: 1 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA 60
MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
Sbjct: 1 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA 60
Query: 61 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF 120
IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
Sbjct: 61 IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF 120
Query: 121 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR 180
KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
Sbjct: 121 KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR 180
Query: 181 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC 240
KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
Sbjct: 181 KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC 240
Query: 241 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID 300
CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
Sbjct: 241 CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID 300
Query: 301 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG 360
NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
Sbjct: 301 NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG 360
Query: 361 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY 420
YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
Sbjct: 361 YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY 420
Query: 421 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI 480
KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
Sbjct: 421 KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI 480
Query: 481 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS 540
DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
Sbjct: 481 DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS 540
Query: 541 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGL 600
IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTS
Sbjct: 541 IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTS---------------- 584
Query: 601 KPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL 660
+TGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL
Sbjct: 585 ----------------------NTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL 622
Query: 661 DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL 720
DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL
Sbjct: 623 DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL 682
Query: 721 PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE 780
PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE
Sbjct: 683 PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE 742
Query: 781 NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ 840
NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ
Sbjct: 743 NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ 802
Query: 841 AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL 900
AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL
Sbjct: 803 AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL 862
Query: 901 IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF 960
IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF
Sbjct: 863 IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF 922
Query: 961 RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI 1020
RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI
Sbjct: 923 RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI 982
Query: 1021 NKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT 1074
NKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT
Sbjct: 983 NKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT 1036
>gi|156564407 phospholipase D2 [Homo sapiens]
Length = 933
Score = 548 bits (1412), Expect = e-155
Identities = 267/472 (56%), Positives = 341/472 (72%), Gaps = 7/472 (1%)
Query: 603 HFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQLDK 662
H++L SE ++P R +L FW GKDY N + KDWVQLD+
Sbjct: 469 HYRLTDLGDSSESAASQPPTP----RPDSPATPDLSHNQFFWLGKDYSNLITKDWVQLDR 524
Query: 663 PFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPK 722
PF DFIDR +TPRMPW D+ VHG ARD+ARHFIQRWNFTK K+KY++ +YP+LLPK
Sbjct: 525 PFEDFIDRETTPRMPWRDVGVVVHGLPARDLARHFIQRWNFTKTTKAKYKTPTYPYLLPK 584
Query: 723 SQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIENQ 782
S +TA++L + +PG VQ+LRS WSAG E SI AY+H I S+H++YIENQ
Sbjct: 585 STSTANQLPFTLPGGQCTTVQVLRSVDRWSAGTL--ENSILNAYLHTIRESQHFLYIENQ 642
Query: 783 FFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQAI 842
FFISC+D + V NK+GD I RILKAH++ YRVYV++PLLPGFEGDISTGGGN++QAI
Sbjct: 643 FFISCSDGRTVLNKVGDEIVDRILKAHKQGWCYRVYVLLPLLPGFEGDISTGGGNSIQAI 702
Query: 843 MHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLLIA 902
+HF YRT+CRGE SIL +LKA +G W +YIS CGLRTH EL G+ V+ELIY+HSK+LIA
Sbjct: 703 LHFTYRTLCRGEYSILHRLKAAMGTAWRDYISICGLRTHGELGGHPVSELIYIHSKVLIA 762
Query: 903 DDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCFRV 962
DD TVIIGSANINDRS+LGKRDSE+AV+++DTET PS+M+G EYQAGRFA LR CF V
Sbjct: 763 DDRTVIIGSANINDRSLLGKRDSELAVLIEDTETEPSLMNGAEYQAGRFALSLRKHCFGV 822
Query: 963 VLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINK 1022
+LG P D++DP+ D FF ++W A NA IY+++FRCLP++ +L LR+++
Sbjct: 823 ILGANTRPDLDLRDPICDDFF-QLWQDMAESNANIYEQIFRCLPSNATRSLRTLREYVAV 881
Query: 1023 PVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT 1074
LA P A EL +++G LV FP FL +ESLLP +G+KE ++P+EVWT
Sbjct: 882 EPLATVSPPLARSELTQVQGHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT 933
Score = 528 bits (1359), Expect = e-149
Identities = 268/491 (54%), Positives = 344/491 (70%), Gaps = 18/491 (3%)
Query: 26 ENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSAIYNTQGFKEPNIQTYLSGCPIKAQV 85
+ LD+ +L E +EVD DP + PF AIY Q K + + G P+ AQV
Sbjct: 13 DELDSSQLQMESDEVDTLKEGEDPA--DRMHPFLAIYELQSLKVHPL-VFAPGVPVTAQV 69
Query: 86 LEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKFKHFQEFHRELLKYKAFIRIPIPTRR 145
+ ER+TS ++V + LY++ LTHG+F W K+K++HFQE HR+LL++K + + +P R
Sbjct: 70 VGTERYTSGSKVGTCTLYSVRLTHGDFSWTTKKKYRHFQELHRDLLRHKVLMSL-LPLAR 128
Query: 146 HTFRRQNVREEP-REMPSLPRSS-ENMIREEQFLGRRKQLEDYLTKILKMPMYRNYHATT 203
R+ REMPSLPR+ E R ++K LE+YL ++L M YRNYHA T
Sbjct: 129 FAVAYSPARDAGNREMPSLPRAGPEGSTRHAA--SKQKYLENYLNRLLTMSFYRNYHAMT 186
Query: 204 EFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNCCGQGRACYRWSKRWLIVKDSFLL 263
EFL++SQLSFI DLG KG+EGMI KRSGGHR+PGL CCG+ + CYRWSKRWL+VKDSFLL
Sbjct: 187 EFLEVSQLSFIPDLGRKGLEGMIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVVKDSFLL 246
Query: 264 YMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRIDNLSRTLILKCNSYRHARWWGGAI 323
YM ++GAI+FV L D F+++VGK+ TE ++G+RID R+LILKC+SYR ARWW I
Sbjct: 247 YMCLETGAISFVQLFDPGFEVQVGKRSTEARHGVRIDTSHRSLILKCSSYRQARWWAQEI 306
Query: 324 EEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKGYFEDVANAMEEANEEIFITDWWL 383
E Q G +FL+ HR SYA + LA+W+VN GYF VA+A+ A EEIFITDWWL
Sbjct: 307 TELAQGPGRDFLQLHRHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIFITDWWL 366
Query: 384 SPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLYKEVELALGINSEYTKRTLMRLHP 443
SPE++LKRP + WRLD +LKRKA++GVR+ I+L+KEVELALGINS Y+KR LM LHP
Sbjct: 367 SPEVYLKRP-AHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRALMLLHP 425
Query: 444 NIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHRLTDVGSVKRV 503
NIKVMRHPD V+ LWAHHEKL+++DQ VAF+GG+DLAYGRWDD +RLTD+G
Sbjct: 426 NIKVMRHPDQVT----LWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGD---- 477
Query: 504 TSGPSLGSLPP 514
S S S PP
Sbjct: 478 -SSESAASQPP 487
>gi|7661880 centaurin beta1 [Homo sapiens]
Length = 740
Score = 34.7 bits (78), Expect = 0.50
Identities = 24/112 (21%), Positives = 53/112 (47%), Gaps = 1/112 (0%)
Query: 216 DLGPKGIEGMIMKRSGGHRIPGLNCCGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFV 275
+LG + E + + GG + G A WS+RW ++ + L+Y K + V
Sbjct: 249 ELGGEEPEPSLREGPGGLVMEGHLFKRASNAFKTWSRRWFTIQSNQLVYQKKYKDPVTVV 308
Query: 276 LLVDKEFKIKVGKKETETKYGIRIDNLSRTLILKCNSYRHARWWGGAIEEFI 327
+ + +K+ ++E ++ + + S++ +L+ +S R + W A++ I
Sbjct: 309 VDDLRLCTVKL-CPDSERRFCFEVVSTSKSCLLQADSERLLQLWVSAVQSSI 359
>gi|22748711 hypothetical protein LOC122046 [Homo sapiens]
Length = 289
Score = 33.5 bits (75), Expect = 1.1
Identities = 19/69 (27%), Positives = 30/69 (43%), Gaps = 6/69 (8%)
Query: 676 MPWH------DIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAHE 729
+PW ++ A+ + R F+ R KI KS + SL + LLP+ T
Sbjct: 124 LPWKIPASMKEVNKALSNQFISLTKRDFVDRSKAQKIKKSSHLSLEWKKLLPQPPDTEFR 183
Query: 730 LRYQVPGSV 738
YQ+P +
Sbjct: 184 RNYQIPAKI 192
>gi|50428933 C1q domain containing 1 isoform 1 [Homo sapiens]
Length = 1127
Score = 33.1 bits (74), Expect = 1.4
Identities = 32/127 (25%), Positives = 52/127 (40%), Gaps = 21/127 (16%)
Query: 79 CPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKFKHFQEFHRELLKYKAFIR 138
CP + + L VE ++ +LY +L G K V +KH ++ +LL F
Sbjct: 262 CPERNESLSVE-----DQMEQSSLYFWDLLEGSEKAVVGTTYKHLKDLLSKLLNSGYFES 316
Query: 139 IPIP---------------TRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRRKQL 183
IP+P + + + E +E SL ++ I+ ++FL RR
Sbjct: 317 IPVPKNAKEKEVPLEEEMLIQSEKKTQLSKTESVKESESLMEFAQPEIQPQEFLNRRYMT 376
Query: 184 E-DYLTK 189
E DY K
Sbjct: 377 EVDYSNK 383
>gi|23503235 C1q domain containing 1 isoform 2 [Homo sapiens]
Length = 1077
Score = 33.1 bits (74), Expect = 1.4
Identities = 32/127 (25%), Positives = 52/127 (40%), Gaps = 21/127 (16%)
Query: 79 CPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKFKHFQEFHRELLKYKAFIR 138
CP + + L VE ++ +LY +L G K V +KH ++ +LL F
Sbjct: 262 CPERNESLSVE-----DQMEQSSLYFWDLLEGSEKAVVGTTYKHLKDLLSKLLNSGYFES 316
Query: 139 IPIP---------------TRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRRKQL 183
IP+P + + + E +E SL ++ I+ ++FL RR
Sbjct: 317 IPVPKNAKEKEVPLEEEMLIQSEKKTQLSKTESVKESESLMEFAQPEIQPQEFLNRRYMT 376
Query: 184 E-DYLTK 189
E DY K
Sbjct: 377 EVDYSNK 383
>gi|32698730 nuclear fragile X mental retardation protein
interacting protein 2 [Homo sapiens]
Length = 695
Score = 33.1 bits (74), Expect = 1.4
Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 21/81 (25%)
Query: 567 HRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGLKPHFKLFHPSSESEQGLTRP--HADT 624
H HH + ++NH +HH+ H +PH L H + S + +P H
Sbjct: 32 HHHHYY-------------FYNHSHNHHHHHHHQQPHQYLQHGAEGSPKAQPKPLKHEQK 78
Query: 625 GSIRSLQ------TGVGELHG 639
+++ Q TG GEL+G
Sbjct: 79 HTLQQHQETPKKKTGYGELNG 99
>gi|238908495 similar to pleckstrin homology domain protein (5V327)
[Homo sapiens]
Length = 506
Score = 32.3 bits (72), Expect = 2.5
Identities = 56/222 (25%), Positives = 91/222 (40%), Gaps = 39/222 (17%)
Query: 244 GRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIK------------VGKKET 291
GR +WS+R+ I+K+SFLLY +S +F +K F I K+E
Sbjct: 41 GRPSAKWSRRFFIIKESFLLYYS-ESEKKSFE--TNKYFNIHPKGVIPLGGCLVEPKEEP 97
Query: 292 ETKYGIRI---DNLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQE 348
Y ++I D L+ + + +W E +Q+ G K+ + G A+ +
Sbjct: 98 SMPYAMKISHQDFHGNILLAAESEFEQTQWL-----EMLQESGKVTWKNAQLGE--AMIK 150
Query: 349 NALAKWYVNAKGYFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRK 408
+ A+ AK E + MEE + E+ L+R E RL+ +L+ +
Sbjct: 151 SLEAQGLQLAKEKQEYLDKLMEE------------TEELCLQREQRE-ELERLNQVLEAE 197
Query: 409 AQQGVRIFIMLYKEVELALGINSEYTKRTLMRLHPNIKVMRH 450
QQ + L E E + E T R L + K +RH
Sbjct: 198 KQQFEEVVQELRMEQE-QIKRELELTARCLKGVEQEKKELRH 238
>gi|154355004 strawberry notch homolog 2 isoform 2 [Homo sapiens]
Length = 1309
Score = 32.0 bits (71), Expect = 3.2
Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 27/192 (14%)
Query: 901 IADDNTVIIGSANIND---RSMLGKRDSEMAVIVQDTETV---------PSVMDGKEYQA 948
+A D V+IG + + R +LG+ D + V E V PS ++ A
Sbjct: 507 LARDKCVVIGLQSTGEARTREVLGENDGHLNCFVSAAEGVFLSLIQKHFPSTKRKRDRGA 566
Query: 949 G---------RFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYD 999
G R A+ RL C + + D S DP D F S + I D
Sbjct: 567 GSKRKRRPRGRGAKAPRLACETAGVIRISDDSSTESDPGLDSDFNSSPESLVDDDVVIVD 626
Query: 1000 KVFRCLPNDEVHNLIQL-RDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLL 1058
V LP+D+ L L RD VL + + ++ ++ L K+R + P L E L+
Sbjct: 627 AV--GLPSDDRGPLCLLQRDPHGPGVLERVERLK-QDLLDKVRRLGRELPVNTLDE--LI 681
Query: 1059 PSVGTKEAIVPM 1070
+G + + M
Sbjct: 682 DQLGGPQRVAEM 693
>gi|154355002 strawberry notch homolog 2 isoform 1 [Homo sapiens]
Length = 1366
Score = 32.0 bits (71), Expect = 3.2
Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 27/192 (14%)
Query: 901 IADDNTVIIGSANIND---RSMLGKRDSEMAVIVQDTETV---------PSVMDGKEYQA 948
+A D V+IG + + R +LG+ D + V E V PS ++ A
Sbjct: 564 LARDKCVVIGLQSTGEARTREVLGENDGHLNCFVSAAEGVFLSLIQKHFPSTKRKRDRGA 623
Query: 949 G---------RFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYD 999
G R A+ RL C + + D S DP D F S + I D
Sbjct: 624 GSKRKRRPRGRGAKAPRLACETAGVIRISDDSSTESDPGLDSDFNSSPESLVDDDVVIVD 683
Query: 1000 KVFRCLPNDEVHNLIQL-RDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLL 1058
V LP+D+ L L RD VL + + ++ ++ L K+R + P L E L+
Sbjct: 684 AV--GLPSDDRGPLCLLQRDPHGPGVLERVERLK-QDLLDKVRRLGRELPVNTLDE--LI 738
Query: 1059 PSVGTKEAIVPM 1070
+G + + M
Sbjct: 739 DQLGGPQRVAEM 750
>gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens]
Length = 1079
Score = 32.0 bits (71), Expect = 3.2
Identities = 27/128 (21%), Positives = 59/128 (46%), Gaps = 7/128 (5%)
Query: 87 EVERFTSTTRVPSINLYTIELTHGEFKWQVKRKFKHFQEFHRELL---KYKAFI--RIPI 141
E+E T + ++ Y+++ E + +V+ +++H++L KY A I + +
Sbjct: 118 EIEGLKETLKALQVSKYSLQKKVSEMEQKVQLHLLAKEDYHKQLSEIEKYYATITGQFGL 177
Query: 142 PTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRRKQLEDYLTKILKMPMYRNYHA 201
H QNVRE + L S+ N +E + +K+L+ + ++K + Y
Sbjct: 178 VKENHEKLEQNVREAIQSNKRL--SALNKKQEAEICSLKKELKKAASDLIKSKVTCQYKM 235
Query: 202 TTEFLDIS 209
E ++++
Sbjct: 236 GEENINLT 243
>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
[Homo sapiens]
Length = 6907
Score = 31.6 bits (70), Expect = 4.2
Identities = 37/177 (20%), Positives = 72/177 (40%), Gaps = 9/177 (5%)
Query: 625 GSIRSLQTGVGELHGETRFWHG--KDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIA 682
GS LQ +G+L G ++ C K W Q+++ AD + + + W +
Sbjct: 5332 GSWEKLQEVIGKLKGLCPSVAEIIEEKCQNTHKRWTQVNQAIADQLQKAQSLLQLWKAYS 5391
Query: 683 SAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANV 742
+A HG+AA AR Q F ++ + +LP + EL++ V + A
Sbjct: 5392 NA-HGEAA---ARLKQQEAKFQQLANISMSGNNLAEILPPALQDIKELQHDVQKTKEA-- 5445
Query: 743 QLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGD 799
L++++ + E S H + + + Y+E + + + V ++ D
Sbjct: 5446 -FLQNSSVLDRLPQPAESSTHMLLPGPLHSLQRAAYLEKMLLVKANEFEFVLSQFKD 5501
>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
[Homo sapiens]
Length = 6885
Score = 31.6 bits (70), Expect = 4.2
Identities = 37/177 (20%), Positives = 72/177 (40%), Gaps = 9/177 (5%)
Query: 625 GSIRSLQTGVGELHGETRFWHG--KDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIA 682
GS LQ +G+L G ++ C K W Q+++ AD + + + W +
Sbjct: 5332 GSWEKLQEVIGKLKGLCPSVAEIIEEKCQNTHKRWTQVNQAIADQLQKAQSLLQLWKAYS 5391
Query: 683 SAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANV 742
+A HG+AA AR Q F ++ + +LP + EL++ V + A
Sbjct: 5392 NA-HGEAA---ARLKQQEAKFQQLANISMSGNNLAEILPPALQDIKELQHDVQKTKEA-- 5445
Query: 743 QLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGD 799
L++++ + E S H + + + Y+E + + + V ++ D
Sbjct: 5446 -FLQNSSVLDRLPQPAESSTHMLLPGPLHSLQRAAYLEKMLLVKANEFEFVLSQFKD 5501
>gi|73747844 ligase III, DNA, ATP-dependent isoform beta precursor
[Homo sapiens]
Length = 949
Score = 31.2 bits (69), Expect = 5.5
Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 15/84 (17%)
Query: 179 RRKQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGL 238
RRK L D + +I M+ T+ LD++ + I + +G+EG+++K G PG
Sbjct: 613 RRKFLHDNMVEIPNRIMFSEMKRVTKALDLADM--ITRVIQEGLEGLVLKDVKGTYEPG- 669
Query: 239 NCCGQGRACYRWSKRWLIVKDSFL 262
+ WL VK +L
Sbjct: 670 ------------KRHWLKVKKDYL 681
>gi|73747829 ligase III, DNA, ATP-dependent isoform alpha precursor
[Homo sapiens]
Length = 1009
Score = 31.2 bits (69), Expect = 5.5
Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 15/84 (17%)
Query: 179 RRKQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGL 238
RRK L D + +I M+ T+ LD++ + I + +G+EG+++K G PG
Sbjct: 613 RRKFLHDNMVEIPNRIMFSEMKRVTKALDLADM--ITRVIQEGLEGLVLKDVKGTYEPG- 669
Query: 239 NCCGQGRACYRWSKRWLIVKDSFL 262
+ WL VK +L
Sbjct: 670 ------------KRHWLKVKKDYL 681
>gi|24797143 sorting nexin 14 isoform b [Homo sapiens]
Length = 893
Score = 30.4 bits (67), Expect = 9.4
Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 10/68 (14%)
Query: 179 RRKQLEDYLTKILKMPMYRNYHATTEFLDIS--QLSFIHDLGP--------KGIEGMIMK 228
+R++ ++YL K+L+ P N +FL + + F+ + P K + G +MK
Sbjct: 603 KREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMK 662
Query: 229 RSGGHRIP 236
G H P
Sbjct: 663 EKGQHLEP 670
>gi|24797145 sorting nexin 14 isoform a [Homo sapiens]
Length = 946
Score = 30.4 bits (67), Expect = 9.4
Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 10/68 (14%)
Query: 179 RRKQLEDYLTKILKMPMYRNYHATTEFLDIS--QLSFIHDLGP--------KGIEGMIMK 228
+R++ ++YL K+L+ P N +FL + + F+ + P K + G +MK
Sbjct: 656 KREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMK 715
Query: 229 RSGGHRIP 236
G H P
Sbjct: 716 EKGQHLEP 723
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 30.4 bits (67), Expect = 9.4
Identities = 16/42 (38%), Positives = 23/42 (54%)
Query: 144 RRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRRKQLED 185
R R Q RE+ E R ENMI+E+Q LG+ ++ E+
Sbjct: 2047 RDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEE 2088
>gi|31742501 sorting nexin family member 27 [Homo sapiens]
Length = 528
Score = 30.4 bits (67), Expect = 9.4
Identities = 23/101 (22%), Positives = 42/101 (41%), Gaps = 6/101 (5%)
Query: 119 KFKHFQEFHRELLKYKAFIR----IPIPTRRHTFRRQNVREEPREM--PSLPRSSENMIR 172
++KH ++ + + Y ++ R QN++ E P LP +
Sbjct: 169 RYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLS 228
Query: 173 EEQFLGRRKQLEDYLTKILKMPMYRNYHATTEFLDISQLSF 213
E+Q RR+ LE+YL K+ + + EFL S ++
Sbjct: 229 EQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDENY 269
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,144,937
Number of Sequences: 37866
Number of extensions: 1798233
Number of successful extensions: 4087
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 4063
Number of HSP's gapped (non-prelim): 31
length of query: 1074
length of database: 18,247,518
effective HSP length: 113
effective length of query: 961
effective length of database: 13,968,660
effective search space: 13423882260
effective search space used: 13423882260
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.