Guide to the Human Genome
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Name: NEK2 Sequence: fasta or formatted (445aa) NCBI GI: 4505373
Description:

NIMA-related kinase 2

Referenced in:

Centrosome
Dual-Specificity Protein Kinases
Spindle, M phase, and Meiosis

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.9         22           2
 C cysteine            1.6          7           1
 D aspartate           4.7         21           1
 E glutamate          10.3         46           2
 F phenylalanine       2.2         10           1
 G glycine             4.7         21           2
 H histidine           1.8          8           1
 I isoleucine          4.7         21           2
 K lysine              8.5         38           3
 L leucine            13.3         59           2
 M methionine          2.7         12           1
 N asparagine          4.3         19           1
 P proline             3.1         14           2
 Q glutamine           4.3         19           1
 R arginine            8.8         39           2
 S serine              7.4         33           2
 T threonine           3.8         17           2
 V valine              4.3         19           1
 W tryptophan          0.4          2           1
 Y tyrosine            4.0         18           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   NIMA-related kinase 2 
NEK5                  0.210   NIMA-related kinase 5 
NEK1                  0.210   NIMA-related kinase 1 
NEK3                  0.208   NIMA-related kinase 3 isoform a 
NEK3                  0.208   NIMA-related kinase 3 isoform a 
NEK3                  0.206   NIMA-related kinase 3 isoform b 
NEK4                  0.196   NIMA-related kinase 4 
NEK9                  0.192   NIMA-related kinase 9 
NEK8                  0.191   NIMA-related kinase 8 
NEK11                 0.183   NIMA-related kinase 11 isoform 2 
NEK11                 0.183   NIMA-related kinase 11 isoform 3 
NEK11                 0.183   NIMA-related kinase 11 isoform 1 
NEK6                  0.173   NIMA-related kinase 6 isoform 1 
NEK6                  0.173   NIMA-related kinase 6 isoform 2 
NEK7                  0.167   NIMA-related kinase 7 
STK36                 0.141   serine/threonine kinase 36 
MARK2                 0.130   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.130   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.130   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.130   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.130   MAP/microtubule affinity-regulating kinase 2 isoform...
MARK4                 0.130   MAP/microtubule affinity-regulating kinase 4 
MARK1                 0.130   MAP/microtubule affinity-regulating kinase 1 
MARK3                 0.129   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.129   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.129   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.129   MAP/microtubule affinity-regulating kinase 3 isoform...
TNIK                  0.129   TRAF2 and NCK interacting kinase isoform 8 
TNIK                  0.129   TRAF2 and NCK interacting kinase isoform 7 
TNIK                  0.129   TRAF2 and NCK interacting kinase isoform 6 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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