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Search of human proteins with 4503999
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503999 gastric inhibitory polypeptide receptor [Homo
sapiens]
(466 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens] 957 0.0
gi|4503947 glucagon receptor [Homo sapiens] 435 e-122
gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens] 371 e-103
gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapi... 346 3e-95
gi|114205383 secretin receptor precursor [Homo sapiens] 283 2e-76
gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens] 266 4e-71
gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens] 265 7e-71
gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens] 250 2e-66
gi|29171759 adenylate cyclase activating polypeptide 1 (pituitar... 249 5e-66
gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens] 239 5e-63
gi|58530851 growth hormone releasing hormone receptor isoform a ... 225 6e-59
gi|5031621 calcitonin receptor-like [Homo sapiens] 189 4e-48
gi|32307159 corticotropin releasing hormone receptor 2 [Homo sap... 180 3e-45
gi|4502547 calcitonin receptor [Homo sapiens] 177 2e-44
gi|19923245 corticotropin releasing hormone receptor 1 isoform 2... 173 3e-43
gi|58530853 growth hormone releasing hormone receptor isoform b ... 164 2e-40
gi|223717971 corticotropin releasing hormone receptor 1 isoform ... 158 9e-39
gi|223717978 corticotropin releasing hormone receptor 1 isoform ... 156 4e-38
gi|223717985 corticotropin releasing hormone receptor 1 isoform ... 140 2e-33
gi|45433552 G protein-coupled receptor 133 [Homo sapiens] 88 2e-17
gi|163792198 latrophilin 3 precursor [Homo sapiens] 77 3e-14
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s... 73 5e-13
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens] 70 3e-12
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens] 70 3e-12
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens] 69 7e-12
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens] 69 7e-12
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens] 69 7e-12
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo... 68 2e-11
gi|6912464 latrophilin 2 precursor [Homo sapiens] 64 4e-10
gi|133930786 egf-like module-containing mucin-like receptor 3 [H... 63 5e-10
>gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]
Length = 466
Score = 957 bits (2475), Expect = 0.0
Identities = 466/466 (100%), Positives = 466/466 (100%)
Query: 1 MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLA 60
MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLA
Sbjct: 1 MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLA 60
Query: 61 CNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCEN 120
CNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCEN
Sbjct: 61 CNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCEN 120
Query: 121 PEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSF 180
PEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSF
Sbjct: 121 PEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSF 180
Query: 181 MLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVY 240
MLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVY
Sbjct: 181 MLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVY 240
Query: 241 LHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIR 300
LHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIR
Sbjct: 241 LHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIR 300
Query: 301 TPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPV 360
TPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPV
Sbjct: 301 TPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPV 360
Query: 361 TEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQ 420
TEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQ
Sbjct: 361 TEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQ 420
Query: 421 RQLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEASRELESYC 466
RQLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEASRELESYC
Sbjct: 421 RQLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEASRELESYC 466
>gi|4503947 glucagon receptor [Homo sapiens]
Length = 477
Score = 435 bits (1118), Expect = e-122
Identities = 231/458 (50%), Positives = 292/458 (63%), Gaps = 19/458 (4%)
Query: 13 LSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLACNGSFDMYVCWD 72
L L LLL Q L+++W+ Y +C L+ PP+ L CN +FD Y CW
Sbjct: 10 LLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNRTFDKYSCWP 69
Query: 73 YAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGL------WRDHTQCE-NPEKNE 125
N TA SCPWYLPWHH V FV ++CG DGQW WRD +QC+ + E+ E
Sbjct: 70 DTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQCQMDGEEIE 129
Query: 126 AFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSFMLRAA 185
+ + QVMYTVGYSLSL LLLAL IL +LHCTRN IH NLF SF+L+A+
Sbjct: 130 VQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASFVLKAS 189
Query: 186 AILSRDRLL-PRPGPYLGDQ-ALALW--NQALAACRTAQIVTQYCVGANYTWLLVEGVYL 241
++L D LL R +GD +++ W + A+A CR A + QY + ANY WLLVEG+YL
Sbjct: 190 SVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYL 249
Query: 242 HSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIRT 301
H+LL L E F YL +GWGAP LFV+PW +V+ L+EN QCW N+ WWI+R
Sbjct: 250 HNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDNMGFWWILRF 309
Query: 302 PILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVT 361
P+ + ILINF IF+RI+ +L++KLR RQM DY+ RLA+STLTL+PLLGVHEVVFA VT
Sbjct: 310 PVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGVHEVVFAFVT 369
Query: 362 EEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQR 421
+E A+G LR AKL F++FLSSFQG LV+VLYCF+NKEVQSE+RR WH RL + L EE+
Sbjct: 370 DEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRLGKVLWEERN 429
Query: 422 QLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEAS 459
RA S PG P S+ L G G G++ S
Sbjct: 430 TSNHRA------SSSPGHGPPSKELQFGR--GGGSQDS 459
>gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]
Length = 463
Score = 371 bits (952), Expect = e-103
Identities = 208/459 (45%), Positives = 270/459 (58%), Gaps = 32/459 (6%)
Query: 11 LRLSLCGL-LLQRAETGSKGQTAG--ELYQRWERYRRECQETLAAAEPPS-GLACNGSFD 66
LRL+L L ++ RA +G T E Q+W YRR+CQ +L PP+ L CN +FD
Sbjct: 8 LRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFD 67
Query: 67 MYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGL-------WRDHTQCE 119
Y CW P + SCPWYLPW V G V R C ++G W WRD ++CE
Sbjct: 68 EYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECE 127
Query: 120 NPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTS 179
++ E + +L L ++YTVGY+LS + L++A IL FR LHCTRNYIH+NLF S
Sbjct: 128 ESKRGERSSPEEQLLF-LYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFAS 186
Query: 180 FMLRAAAILSRDRLLPRPGPYLGDQALALWNQALA-----ACRTAQIVTQYCVGANYTWL 234
F+LRA ++ +D L Q W+ L+ +CR ++ QYCV ANY WL
Sbjct: 187 FILRALSVFIKDAALKWMYSTAAQQHQ--WDGLLSYQDSLSCRLVFLLMQYCVAANYYWL 244
Query: 235 LVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKA 294
LVEGVYL++LL SE+ FR Y+ +GWG P LFV+PW IV+YLYE+ CW RN
Sbjct: 245 LVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMN 304
Query: 295 IWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHE 354
W IIR PIL I +NFLIF+R++ I++SKL+ M D + RLA+STLTL+PLLG HE
Sbjct: 305 YWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHE 364
Query: 355 VVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRR 414
V+FA V +E ARG LRF KL E+ +SFQG +V++LYCF+N EVQ E R+ W RL
Sbjct: 365 VIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRL-- 422
Query: 415 SLGEEQRQLPERAFRALPSGSGPGEVPTSRGLSSGTLPG 453
E S P + PTS LSSG G
Sbjct: 423 ----------EHLHIQRDSSMKPLKCPTS-SLSSGATAG 450
>gi|4758438 glucagon-like peptide 2 receptor precursor [Homo
sapiens]
Length = 553
Score = 346 bits (887), Expect = 3e-95
Identities = 180/423 (42%), Positives = 258/423 (60%), Gaps = 22/423 (5%)
Query: 5 PILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLACNGS 64
P L L+L +S+ + TGS + E ++W +Y++ C L + PSG+ CNG+
Sbjct: 51 PFLTLVLLVSI------KQVTGSLLE---ETTRKWAQYKQACLRDLL--KEPSGIFCNGT 99
Query: 65 FDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQW-------GLWRDHTQ 117
FD YVCW +++P + CP YLPW ++G R C + G W +W+D ++
Sbjct: 100 FDQYVCWPHSSPGNVS-VPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSE 158
Query: 118 CENPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLF 177
C + +D+ +L LQ+MYTVGYS SL +L LAL +L R+LHCTRNYIH+NLF
Sbjct: 159 CSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMNLF 218
Query: 178 TSFMLRAAAILSRDRLLPRPGPYLGDQA---LALWNQALAACRTAQIVTQYCVGANYTWL 234
SF+LR A+L +D + D ++ ++ +CR+ Q++ Y VGANY WL
Sbjct: 219 ASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMSTSCRSVQVLLHYFVGANYLWL 278
Query: 235 LVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKA 294
LVEG+YLH+LL E + YLLLGW P LFV+PW R ENT CW N K
Sbjct: 279 LVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGFARAHLENTGCWTTNGNKK 338
Query: 295 IWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHE 354
IWWIIR P+++ + +NF IF++IL +L+SKL+ QM RDY+ RLA+STL L+PLLGVHE
Sbjct: 339 IWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLVLIPLLGVHE 398
Query: 355 VVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRR 414
++F+ +T++Q G + +L ++ LSSF GFLV++ Y F N EV++E+R+ W L R
Sbjct: 399 ILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKYWVRFLLAR 458
Query: 415 SLG 417
G
Sbjct: 459 HSG 461
>gi|114205383 secretin receptor precursor [Homo sapiens]
Length = 440
Score = 283 bits (724), Expect = 2e-76
Identities = 168/420 (40%), Positives = 234/420 (55%), Gaps = 29/420 (6%)
Query: 5 PILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQET-------LAAAEPPS 57
P+ QLLL + L TG+ + L WE + QE L +P
Sbjct: 8 PLQQLLLPVLLA---CAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTEQPVP 64
Query: 58 GLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWG--LWRDH 115
G C G +D CW + P CP +L G + R C DG W R +
Sbjct: 65 G--CEGMWDNISCWPSSVPGRMVEVECPRFLRMLTS-RNGSLFRNCTQDG-WSETFPRPN 120
Query: 116 TQCENPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHIN 175
C + + + L +L+VMYTVGYS SL LL+AL IL FRRLHCTRNYIH++
Sbjct: 121 LACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMH 180
Query: 176 LFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLL 235
LF SF+LRA + +D +L + + A C+ ++ QYC+ ANY+WLL
Sbjct: 181 LFVSFILRALSNFIKDAVL------FSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLL 234
Query: 236 VEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAI 295
VEG+YLH+LL + SE + + ++ GWG+PA+FV W I R+ E+ CW+ N +I
Sbjct: 235 VEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASI 294
Query: 296 WWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRD--YRLRLARSTLTLVPLLGVH 353
WWIIR P++++ILINF++FI IL IL+ KLRT++ R + + RLARSTL L+PL G+H
Sbjct: 295 WWIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIH 354
Query: 354 EVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLR 413
+VFA E+ +L FE+ L SFQG +V+VLYCF+N EVQ E+++ W LR
Sbjct: 355 YIVFAFSPEDAME-----IQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLR 409
>gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]
Length = 593
Score = 266 bits (679), Expect = 4e-71
Identities = 157/410 (38%), Positives = 226/410 (55%), Gaps = 45/410 (10%)
Query: 28 KGQTAGELYQRWERYRRECQETLAAAEPPSGLACNGSFDMYVCWDYAAPNATARASCPWY 87
K + +G+LY E + + P C +D +CW AP CP Y
Sbjct: 80 KDKASGKLYPESEEDKEAPTGSRYRGRP-----CLPEWDHILCWPLGAPGEVVAVPCPDY 134
Query: 88 LPWHHHVAAGFVLRQCGSDGQWGL-------WRDHTQCENPEKNEAFLDQRLILERLQVM 140
+ +H G R+C +G W L W ++++C NE +R + +RL ++
Sbjct: 135 IYDFNH--KGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNET--REREVFDRLGMI 190
Query: 141 YTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPY 200
YTVGYS+SLA+L +A+LIL+ FRRLHCTRNYIH++LF SFMLRA +I +D +L Y
Sbjct: 191 YTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVL-----Y 245
Query: 201 LG---DQALALWNQAL-----------------AACRTAQIVTQYCVGANYTWLLVEGVY 240
G D+A L + L A CR A Y + NY W+LVEG+Y
Sbjct: 246 SGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLY 305
Query: 241 LHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIR 300
LHSL+ + SE+ + + + GWG PA+FV WV VR NT CW+ + WII+
Sbjct: 306 LHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNK-KWIIQ 364
Query: 301 TPILMTILINFLIFIRILGILLSKLR-TRQMRC--RDYRLRLARSTLTLVPLLGVHEVVF 357
PIL +I++NF++FI I+ +L +KLR T RC R +L +STL L+PL GVH +VF
Sbjct: 365 VPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVF 424
Query: 358 APVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGW 407
+ G L ++ +E+ +SFQGF V+++YCF N EVQ+EI++ W
Sbjct: 425 MATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSW 474
>gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]
Length = 457
Score = 265 bits (677), Expect = 7e-71
Identities = 160/414 (38%), Positives = 224/414 (54%), Gaps = 30/414 (7%)
Query: 59 LACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQC 118
+ C+ +D CW +CP + V R C +G W
Sbjct: 61 IGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEG----WTHLEPG 116
Query: 119 ENP-----EKNEAFLD--QRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNY 171
P + A LD Q + ++ YT+GY LSLATLL+A ILSLFR+LHCTRNY
Sbjct: 117 PYPIACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNY 176
Query: 172 IHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANY 231
IH++LF SF+LRAAA+ +D L G DQ ++ C+ A + QYCV AN+
Sbjct: 177 IHMHLFISFILRAAAVFIKDLALFDSGE--SDQC----SEGSVGCKAAMVFFQYCVMANF 230
Query: 232 TWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNE 291
WLLVEG+YL++LL + SE +F Y+L+GWG P+ F + W I R +E+ CW+
Sbjct: 231 FWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTIN 290
Query: 292 VKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYR--LRLARSTLTLVPL 349
++WWII+ PIL +IL+NF++FI I+ ILL KLR +R D RLARSTL L+PL
Sbjct: 291 -SSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPL 349
Query: 350 LGVHEVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHH 409
GVH ++FA + K+ FE+ + SFQGF+V++LYCF+N EVQ+E+RR W
Sbjct: 350 FGVHYIMFAFFPDNFKPE----VKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRR 405
Query: 410 CRLRRSLGEEQRQLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEASRELE 463
L+ LG + +R GS T + + PG +S + E
Sbjct: 406 WHLQGVLGWNPK------YRHPSGGSNGATCSTQVSMLTRVSPGARRSSSFQAE 453
>gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]
Length = 438
Score = 250 bits (639), Expect = 2e-66
Identities = 148/372 (39%), Positives = 210/372 (56%), Gaps = 27/372 (7%)
Query: 45 ECQETLAAAEPPSGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCG 104
+C E L + + AC+G +D CW A T CP + + AG + + C
Sbjct: 37 KCAELLRS-QTEKHKACSGVWDNITCWRPANVGETVTVPCPKVFS-NFYSKAGNISKNCT 94
Query: 105 SDGQWGLWRDHTQC---ENPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSL 161
SDG + D +PE L+ + +YT+GYS+SL +L +IL L
Sbjct: 95 SDGWSETFPDFVDACGYSDPEDESKITFYILV----KAIYTLGYSVSLMSLATGSIILCL 150
Query: 162 FRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQ--ALAACRTA 219
FR+LHCTRNYIH+NLF SF+LRA ++L +D +L Y L +Q + C+ +
Sbjct: 151 FRKLHCTRNYIHLNLFLSFILRAISVLVKDDVL-----YSSSGTLHCPDQPSSWVGCKLS 205
Query: 220 QIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRY 279
+ QYC+ AN+ WLLVEG+YLH+LLV + F YLL+GWG P + + W R
Sbjct: 206 LVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRC-FLAYLLIGWGLPTVCIGAWTAARL 264
Query: 280 LYENTQCWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYR--L 337
E+T CW+ N+ WW+IR PIL++I++NF++FI I+ ILL KL + + D
Sbjct: 265 YLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYK 324
Query: 338 RLARSTLTLVPLLGVHEVVFA--PVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFI 395
RLA+STL L+PL GVH +VFA P++ L FE+ L SFQG +V+VLYCF+
Sbjct: 325 RLAKSTLLLIPLFGVHYMVFAVFPISISSKYQIL------FELCLGSFQGLVVAVLYCFL 378
Query: 396 NKEVQSEIRRGW 407
N EVQ E++R W
Sbjct: 379 NSEVQCELKRKW 390
>gi|29171759 adenylate cyclase activating polypeptide 1 (pituitary)
receptor type I precursor [Homo sapiens]
Length = 468
Score = 249 bits (635), Expect = 5e-66
Identities = 144/384 (37%), Positives = 204/384 (53%), Gaps = 37/384 (9%)
Query: 57 SGLACNGSFDMYVCWDYAAPNATARASCPWYLP-------WHHHVAA------------- 96
S C G +D CW A SCP W
Sbjct: 50 SSPGCPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLS 109
Query: 97 --GFVLRQCGSDGQWGLWRDH--TQCENPEKNEAFLDQRLILERLQVMYTVGYSLSLATL 152
G V R C DG W H C E DQ ++ +YTVGYS SL TL
Sbjct: 110 DMGVVSRNCTEDG-WSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTL 168
Query: 153 LLALLILSLFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQA 212
A++IL FR+LHCTRN+IH+NLF SFMLRA ++ +D +L +Q +
Sbjct: 169 TTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWIL------YAEQDSNHCFIS 222
Query: 213 LAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVI 272
C+ + YCV +NY WL +EG+YL +LLV E +F +Y ++GWG P + V
Sbjct: 223 TVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVT 282
Query: 273 PWVIVRYLYENTQCWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRC 332
W +R +++T CW+ N+ A+WW+I+ P++ +I++NF++FI I+ IL+ KL++ M
Sbjct: 283 VWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGG 342
Query: 333 RD--YRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSV 390
+ LRLARSTL L+PL G+H VFA E ++ +L FE+ L SFQGF+V+V
Sbjct: 343 NESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKR----ERLVFELGLGSFQGFVVAV 398
Query: 391 LYCFINKEVQSEIRRGWHHCRLRR 414
LYCF+N EVQ+EI+R W ++ R
Sbjct: 399 LYCFLNGEVQAEIKRKWRSWKVNR 422
>gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]
Length = 550
Score = 239 bits (609), Expect = 5e-63
Identities = 145/430 (33%), Positives = 220/430 (51%), Gaps = 40/430 (9%)
Query: 13 LSLCGLLLQRAETGSKGQ-TAGELYQRWERYRRECQETLAAAEPPSGLACNGSFDMYVCW 71
L L LL RA+ S G T E + + +C+ + A C +D +CW
Sbjct: 14 LMLGSCLLARAQLDSDGTITIEEQIVLVLKAKVQCELNITAQLQEGEGNCFPEWDGLICW 73
Query: 72 DYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGL-------WRDHTQCENPEKN 124
+ CP Y+ +H F R C +G W W +++ C +
Sbjct: 74 PRGTVGKISAVPCPPYIYDFNHKGVAF--RHCNPNGTWDFMHSLNKTWANYSDCLRFLQP 131
Query: 125 EAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSFMLRA 184
+ + ++ ERL VMYTVGYS+S +L +A+LI+ FRRLHCTRNYIH++LF SFMLRA
Sbjct: 132 DISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHMHLFVSFMLRA 191
Query: 185 AAILSRDR-------------LLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANY 231
+I +DR L+ + P +A ++ C+ A ++ Y + NY
Sbjct: 192 TSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAVVMFIYFLATNY 251
Query: 232 TWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNE 291
W+LVEG+YLH+L+ + S+ + ++L+GWG PA FV W + R + +CWE +
Sbjct: 252 YWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVARATLADARCWELS- 310
Query: 292 VKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYR---LRLARSTLTLVP 348
I WI + PIL I +NF++F+ + +L +K+ D R +LA+STL LV
Sbjct: 311 AGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQYRKLAKSTLVLVL 370
Query: 349 LLGVHEVVFAPVTEEQARGALRFAKLGFEI------FLSSFQGFLVSVLYCFINKEVQSE 402
+ GVH +VF + F LG+EI F +SFQGF VS++YC+ N EVQ+E
Sbjct: 371 VFGVHYIVFVCLPHS-------FTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAE 423
Query: 403 IRRGWHHCRL 412
+++ W L
Sbjct: 424 VKKMWSRWNL 433
>gi|58530851 growth hormone releasing hormone receptor isoform a
precursor [Homo sapiens]
Length = 423
Score = 225 bits (574), Expect = 6e-59
Identities = 126/370 (34%), Positives = 197/370 (53%), Gaps = 16/370 (4%)
Query: 43 RRECQETLAAAE--PPSGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVL 100
R + L AAE P + L C ++D +CW A CP + H +G V
Sbjct: 35 REDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFS-HFSSESGAVK 93
Query: 101 RQCGSDGQWGLWRDHTQCENPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILS 160
R C G W P E ++ ++++YTVG+S+S+ L +A+ IL
Sbjct: 94 RDCTITG-WSEPFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILV 152
Query: 161 LFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQ 220
RRLHC RNY+H LFT+F+L+A A+ +D L + D ++ L C+ +
Sbjct: 153 ALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALF----HSDDTDHCSFSTVL--CKVSV 206
Query: 221 IVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYL 280
+ + N++WLL E VYL+ LL S F + +L GWG P LF WV +
Sbjct: 207 AASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLA 266
Query: 281 YENTQCWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQ--MRCRDYRLR 338
+E+ CW+ ++ WWII+ PI++++ +NF +F+ I+ IL+ KL Q + + R
Sbjct: 267 FEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWR 326
Query: 339 LARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKE 398
L++STL L+PL G+H ++F + + G +L E+ L SFQGF+V++LYCF+N+E
Sbjct: 327 LSKSTLFLIPLFGIHYIIFNFLPDNAGLG----IRLPLELGLGSFQGFIVAILYCFLNQE 382
Query: 399 VQSEIRRGWH 408
V++EI R WH
Sbjct: 383 VRTEISRKWH 392
>gi|5031621 calcitonin receptor-like [Homo sapiens]
Length = 461
Score = 189 bits (481), Expect = 4e-48
Identities = 126/409 (30%), Positives = 204/409 (49%), Gaps = 50/409 (12%)
Query: 20 LQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLACNGSFDMYVCWDYAAPNAT 79
+Q T +K TA ++E Y++ Q+ + AE G+ CN ++D ++CW+ A
Sbjct: 32 IQLGVTRNKIMTA-----QYECYQKIMQDPIQQAE---GVYCNRTWDGWLCWNDVAAGTE 83
Query: 80 ARASCPWYLPWHHHVAAGFVLRQCGSDGQW-------GLWRDHTQCE--NPEKNEAFLDQ 130
+ CP Y + + V + C DG W W ++TQC EK + L+
Sbjct: 84 SMQLCPDY--FQDFDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALN- 140
Query: 131 RLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSFMLRAAAILSR 190
L + +G+ LS+A+LL++L I F+ L C R +H NLF SF+ + +
Sbjct: 141 ------LFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIH 194
Query: 191 DRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGG 250
+ +QAL N +C+ +Q + Y +G NY W+L EG+YLH+L+V+
Sbjct: 195 LTAVAN------NQALVATNPV--SCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVF 246
Query: 251 SEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIRTPILMTILIN 310
+E+ H +Y LGWG P + I R LY N CW ++ + +II PI +L+N
Sbjct: 247 AEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLL-YIIHGPICAALLVN 305
Query: 311 FLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALR 370
+ I+ +L++KL+ + ++ R+TL LVPLLG+ E V P E
Sbjct: 306 LFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGI-EFVLIPWRPE------- 357
Query: 371 FAKLGFEIF------LSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLR 413
K+ E++ L FQG LVS ++CF N EVQ+ +RR W+ +++
Sbjct: 358 -GKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQ 405
>gi|32307159 corticotropin releasing hormone receptor 2 [Homo
sapiens]
Length = 411
Score = 180 bits (456), Expect = 3e-45
Identities = 115/361 (31%), Positives = 175/361 (48%), Gaps = 22/361 (6%)
Query: 61 CNGSFDMY-VCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCE 119
CN + D CW +A A CP Y + R+C +G W +++QCE
Sbjct: 40 CNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCE 99
Query: 120 ---NPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINL 176
+ ++ + L R+ L V+ +G+ +S+A L+ A L+ R + C RN IH NL
Sbjct: 100 PILDDKQRKYDLHYRIAL----VVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNL 155
Query: 177 FTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLV 236
T+F+LR L D + N+ C T + Y V N+ W+ V
Sbjct: 156 ITTFILRNVMWFLLQ---------LVDHEVHESNEVWCRCITT--IFNYFVVTNFFWMFV 204
Query: 237 EGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEV-KAI 295
EG YLH+ +V+ +E +L +GW P ++ W I + YEN QCW E +
Sbjct: 205 EGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFGKEPGDLV 264
Query: 296 WWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEV 355
+I + PI++ +LINF+ I+ IL++KLR + ++TL L+PLLG+ +
Sbjct: 265 DYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYM 324
Query: 356 VFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRS 415
+F E + F + F FL SFQGF VSV YCF N EV+S +R+ WH + S
Sbjct: 325 LFFVNPGEDDLSQIMF--IYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRWHRWQDHHS 382
Query: 416 L 416
L
Sbjct: 383 L 383
>gi|4502547 calcitonin receptor [Homo sapiens]
Length = 474
Score = 177 bits (448), Expect = 2e-44
Identities = 117/396 (29%), Positives = 193/396 (48%), Gaps = 37/396 (9%)
Query: 58 GLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQW-------G 110
G CN ++D ++CWD + CP Y P + V + C G W
Sbjct: 69 GPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFP--DFDPSEKVTKYCDEKGVWFKHPENNR 126
Query: 111 LWRDHTQCE--NPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCT 168
W ++T C PEK L +L L + VG+SLS+ TL+++L I FR L C
Sbjct: 127 TWSNYTMCNAFTPEK----LKNAYVLYYLAI---VGHSLSIFTLVISLGIFVFFRSLGCQ 179
Query: 169 RNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVG 228
R +H N+F +++L + I+ + G L + +C+ QY +
Sbjct: 180 RVTLHKNMFLTYILNSMIIIIHLVEVVPNGE--------LVRRDPVSCKILHFFHQYMMA 231
Query: 229 ANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWE 288
NY W+L EG+YLH+L+V+ +E+ R+Y LLGWG P + I R +Y N CW
Sbjct: 232 CNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWL 291
Query: 289 RNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVP 348
E + +II P++ +++NF + I+ +L++K+R L+ ++T+ LVP
Sbjct: 292 SVETHLL-YIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVP 350
Query: 349 LLGVHEVVFAPVTEEQARGALRFAKLGFEIFLSS---FQGFLVSVLYCFINKEVQSEIRR 405
LLG+ VVF + G + ++ + S FQGF V+ +YCF N EVQ+ ++R
Sbjct: 351 LLGIQFVVFPWRPSNKMLGKI------YDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKR 404
Query: 406 GWHHCRLRRSLGEEQRQLPERAFRALPSGSGPGEVP 441
W +++ + R+ R+ RA + + G++P
Sbjct: 405 QWAQFKIQWN-QRWGRRPSNRSARAAAAAAEAGDIP 439
>gi|19923245 corticotropin releasing hormone receptor 1 isoform 2
[Homo sapiens]
Length = 415
Score = 173 bits (438), Expect = 3e-43
Identities = 114/377 (30%), Positives = 186/377 (49%), Gaps = 28/377 (7%)
Query: 48 ETLAAAEPPSGLACNGSFDMY-VCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSD 106
E+L+ A SGL CN S D+ CW + CP + + R+C ++
Sbjct: 31 ESLSLASNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLAN 90
Query: 107 GQWGLWRDHTQCE---NPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFR 163
G W ++++C+ N EK ++ ++ +G+ +SL LL+A ++ R
Sbjct: 91 GSWAARVNYSECQEILNEEKKS-----KVHYHVAVIINYLGHCISLVALLVAFVLFLRLR 145
Query: 164 RLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVT 223
+ C RN IH NL ++F+LR A +L P + Q+ W CR
Sbjct: 146 SIRCLRNIIHWNLISAFILRNATWFVV-QLTMSPEVH---QSNVGW------CRLVTAAY 195
Query: 224 QYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYEN 283
Y N+ W+ EG YLH+ +VL ++ ++ +GWG P ++ W I + Y+N
Sbjct: 196 NYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDN 255
Query: 284 TQCW--ERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLAR 341
+CW +R V +I + P+++ +LINF+ I+ IL++KLR + +
Sbjct: 256 EKCWFGKRPGVYTD-YIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVK 314
Query: 342 STLTLVPLLGVHEVVF--APVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEV 399
+TL L+PLLG+ ++F P +E +R + F FL SFQGF VSV YCF+N EV
Sbjct: 315 ATLVLLPLLGITYMLFFVNPGEDEVSRVVFIY----FNSFLESFQGFFVSVFYCFLNSEV 370
Query: 400 QSEIRRGWHHCRLRRSL 416
+S IR+ WH + + S+
Sbjct: 371 RSAIRKRWHRWQDKHSI 387
>gi|58530853 growth hormone releasing hormone receptor isoform b
precursor [Homo sapiens]
Length = 337
Score = 164 bits (414), Expect = 2e-40
Identities = 93/289 (32%), Positives = 145/289 (50%), Gaps = 10/289 (3%)
Query: 43 RRECQETLAAAE--PPSGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVL 100
R + L AAE P + L C ++D +CW A CP + H +G V
Sbjct: 35 REDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFS-HFSSESGAVK 93
Query: 101 RQCGSDGQWGLWRDHTQCENPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILS 160
R C G W P E ++ ++++YTVG+S+S+ L +A+ IL
Sbjct: 94 RDCTITG-WSEPFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILV 152
Query: 161 LFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQ 220
RRLHC RNY+H LFT+F+L+A A+ +D L + D ++ L C+ +
Sbjct: 153 ALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALF----HSDDTDHCSFSTVL--CKVSV 206
Query: 221 IVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYL 280
+ + N++WLL E VYL+ LL S F + +L GWG P LF WV +
Sbjct: 207 AASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLA 266
Query: 281 YENTQCWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQ 329
+E+ CW+ ++ WWII+ PI++++ +NF +F+ I+ IL+ KL Q
Sbjct: 267 FEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQ 315
>gi|223717971 corticotropin releasing hormone receptor 1 isoform 1
[Homo sapiens]
Length = 444
Score = 158 bits (400), Expect = 9e-39
Identities = 114/406 (28%), Positives = 187/406 (46%), Gaps = 57/406 (14%)
Query: 48 ETLAAAEPPSGLACNGSFDMY-VCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSD 106
E+L+ A SGL CN S D+ CW + CP + + R+C ++
Sbjct: 31 ESLSLASNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLAN 90
Query: 107 GQWGLWRDHTQCE---NPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLIL---- 159
G W ++++C+ N EK ++ ++ +G+ +SL LL+A ++
Sbjct: 91 GSWAARVNYSECQEILNEEKKS-----KVHYHVAVIINYLGHCISLVALLVAFVLFLRLR 145
Query: 160 -------------------------SLFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLL 194
+ R + C RN IH NL ++F+LR A +L
Sbjct: 146 PGCTHWGDQADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVV-QLT 204
Query: 195 PRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEG 254
P + Q+ W CR Y N+ W+ EG YLH+ +VL ++
Sbjct: 205 MSPEVH---QSNVGW------CRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRL 255
Query: 255 HFRYYLLLGWGAPALFVIPWVIVRYLYENTQCW--ERNEVKAIWWIIRTPILMTILINFL 312
++ +GWG P ++ W I + Y+N +CW +R V +I + P+++ +LINF+
Sbjct: 256 RKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTD-YIYQGPMILVLLINFI 314
Query: 313 IFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVF--APVTEEQARGALR 370
I+ IL++KLR + ++TL L+PLLG+ ++F P +E +R
Sbjct: 315 FLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFI 374
Query: 371 FAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSL 416
+ F FL SFQGF VSV YCF+N EV+S IR+ WH + + S+
Sbjct: 375 Y----FNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSI 416
>gi|223717978 corticotropin releasing hormone receptor 1 isoform 3
[Homo sapiens]
Length = 375
Score = 156 bits (394), Expect = 4e-38
Identities = 100/323 (30%), Positives = 166/323 (51%), Gaps = 27/323 (8%)
Query: 101 RQCGSDGQWGLWRDHTQCE---NPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALL 157
R+C ++G W ++++C+ N EK ++ ++ +G+ +SL LL+A +
Sbjct: 45 RECLANGSWAARVNYSECQEILNEEKKS-----KVHYHVAVIINYLGHCISLVALLVAFV 99
Query: 158 ILSLFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACR 217
+ R + C RN IH NL ++F+LR A +L P + Q+ W CR
Sbjct: 100 LFLRLRSIRCLRNIIHWNLISAFILRNATWFVV-QLTMSPEVH---QSNVGW------CR 149
Query: 218 TAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIV 277
Y N+ W+ EG YLH+ +VL ++ ++ +GWG P ++ W I
Sbjct: 150 LVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIG 209
Query: 278 RYLYENTQCW--ERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDY 335
+ Y+N +CW +R V +I + P+++ +LINF+ I+ IL++KLR
Sbjct: 210 KLYYDNEKCWFGKRPGVYTD-YIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQ 268
Query: 336 RLRLARSTLTLVPLLGVHEVVF--APVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYC 393
+ ++TL L+PLLG+ ++F P +E +R + F FL SFQGF VSV YC
Sbjct: 269 YRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIY----FNSFLESFQGFFVSVFYC 324
Query: 394 FINKEVQSEIRRGWHHCRLRRSL 416
F+N EV+S IR+ WH + + S+
Sbjct: 325 FLNSEVRSAIRKRWHRWQDKHSI 347
>gi|223717985 corticotropin releasing hormone receptor 1 isoform 4
[Homo sapiens]
Length = 401
Score = 140 bits (354), Expect = 2e-33
Identities = 104/377 (27%), Positives = 175/377 (46%), Gaps = 42/377 (11%)
Query: 48 ETLAAAEPPSGLACNGSFDMY-VCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSD 106
E+L+ A SGL CN S D+ CW + CP + + R+C ++
Sbjct: 31 ESLSLASNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLAN 90
Query: 107 GQWGLWRDHTQCE---NPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFR 163
G W ++++C+ N EK ++ ++ +G+ +SL LL+A ++ R
Sbjct: 91 GSWAARVNYSECQEILNEEKKS-----KVHYHVAVIINYLGHCISLVALLVAFVLFLRLR 145
Query: 164 RLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVT 223
+ C RN IH NL ++F+LR A +L P + Q+ W CR
Sbjct: 146 SIRCLRNIIHWNLISAFILRNATWFVV-QLTMSPEVH---QSNVGW------CRLVTAAY 195
Query: 224 QYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYEN 283
Y N+ W+ EG YLH+ +VL ++ ++ +GWG P ++ W I + Y+N
Sbjct: 196 NYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDN 255
Query: 284 TQCW--ERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLAR 341
+CW +R V +I + P+++ +LINF+ I+ IL++KLR + +
Sbjct: 256 EKCWFGKRPGVYTD-YIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVK 314
Query: 342 STLTLVPLLGVHEVVF--APVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEV 399
+TL L+PLLG+ ++F P +E +R + F FL SFQ V
Sbjct: 315 ATLVLLPLLGITYMLFFVNPGEDEVSRVVFIY----FNSFLESFQ--------------V 356
Query: 400 QSEIRRGWHHCRLRRSL 416
+S IR+ WH + + S+
Sbjct: 357 RSAIRKRWHRWQDKHSI 373
>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
Length = 874
Score = 87.8 bits (216), Expect = 2e-17
Identities = 78/315 (24%), Positives = 136/315 (43%), Gaps = 47/315 (14%)
Query: 143 VGYSLSLATLLLALLILSLFRRLHCTRN---YIHINLFTSFMLRAAAILSRDRLLPRPGP 199
VG SLS+ L+ L+ ++ + RN +IH NL + ++ +L RL P P
Sbjct: 572 VGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPGTTP 631
Query: 200 YLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYY 259
C+ ++ Y + + W+LVEG++L+S+++ V GSE+ RYY
Sbjct: 632 ----------------CQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYY 675
Query: 260 LLLGWGAPALFVI---PWVIVRYLYENTQCWERNEVKAIWWIIRTPILMTILINFLIFIR 316
+GWG P L I + + Y N CW AIW + P L I++N I I
Sbjct: 676 YGMGWGFPLLICIISLSFAMDSYGTSN-NCWLSLASGAIWAFV-APALFVIVVNIGILIA 733
Query: 317 ILGILLSKLRTRQMRCRDYRLR--------LARSTLTLVPLLGVHEVVFAPVTEEQARGA 368
+ ++ Q+ +Y++ A++ L+P+LG VF +
Sbjct: 734 VTRVI------SQISADNYKIHGDPSAFKLTAKAVAVLLPILGT-SWVFGVLAVNGCAVV 786
Query: 369 LRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQRQLPERAF 428
++ L+S QG + + +C +N EV++ + H ++ R + F
Sbjct: 787 FQY----MFATLNSLQGLFIFLFHCLLNSEVRAAFK---HKTKVWSLTSSSARTSNAKPF 839
Query: 429 RA-LPSGSGPGEVPT 442
+ L +G+ PG T
Sbjct: 840 HSDLMNGTRPGMAST 854
>gi|163792198 latrophilin 3 precursor [Homo sapiens]
Length = 1469
Score = 77.4 bits (189), Expect = 3e-14
Identities = 77/280 (27%), Positives = 114/280 (40%), Gaps = 37/280 (13%)
Query: 137 LQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPR 196
L V+ VG LSL LL+ + FR L RN IH NL S + L +
Sbjct: 877 LDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQ 936
Query: 197 PGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHF 256
P AC + + A +TW+ +EGV L+ +LV V SE
Sbjct: 937 P----------------IACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRR 980
Query: 257 RYYLLLGWGAPALFVIPWVIVRYLYENTQ--CWERNEVKAIWWIIRTPILMTILINFLIF 314
+Y+ L+G+G PAL V V Y T CW R + IW I P + I++N +
Sbjct: 981 KYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFI-GPATLIIMLNVI-- 1037
Query: 315 IRILGILLSKLRTR------------QMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVTE 362
LGI L K+ + D R + + + LL + + +A
Sbjct: 1038 --FLGIALYKMFHHTAILKPESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTWAFGLM 1095
Query: 363 EQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSE 402
+ A L F IF +S QG + + +C + K+V+ E
Sbjct: 1096 YINESTVIMAYL-FTIF-NSLQGMFIFIFHCVLQKKVRKE 1133
>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
sapiens]
Length = 3014
Score = 73.2 bits (178), Expect = 5e-13
Identities = 88/354 (24%), Positives = 142/354 (40%), Gaps = 39/354 (11%)
Query: 102 QCGSDGQWGLWRDHTQCENPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSL 161
QC + + D ++ EN E + L+++ SLSLA LL+A ++LSL
Sbjct: 2444 QCSHTASFAVLMDISRRENGE-----------VLPLKIVTYAAVSLSLAALLVAFVLLSL 2492
Query: 162 FRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQI 221
R L + IH +L + L + + P+L C I
Sbjct: 2493 VRMLRSNLHSIHKHLAVALFLSQLVFVIG--INQTENPFL--------------CTVVAI 2536
Query: 222 VTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFV-IPWVIVRYL 280
+ Y + + W LVE ++++ +L V + G R+Y ++GWG PA+ + +
Sbjct: 2537 LLHYIYMSTFAWTLVESLHVYRMLTEVRNIDTGPMRFYYVVGWGIPAIVTGLAVGLDPQG 2596
Query: 281 YENTQ-CWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRL 339
Y N CW + I W PI I+IN + +L +S R + + L
Sbjct: 2597 YGNPDFCWLSLQDTLI-WSFAGPIGAVIIINTV--TSVLSAKVSCQRKHHYYGKKGIVSL 2653
Query: 340 ARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEV 399
R+ L+ L+ ++ R AL F L F IF S QG V + +C +N+EV
Sbjct: 2654 LRTAFLLLLLISATWLLGLLAVN---RDALSFHYL-FAIF-SGLQGPFVLLFHCVLNQEV 2708
Query: 400 QSEIR--RGWHHCRLRRSLGEEQRQLPERAFRALPSGSGPGEVPTSRGLSSGTL 451
+ ++ G L S L G GP + T G S+ +L
Sbjct: 2709 RKHLKGVLGGRKLHLEDSATTRATLLTRSLNCNTTFGDGPDMLRTDLGESTASL 2762
>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
Length = 1474
Score = 70.5 bits (171), Expect = 3e-12
Identities = 81/305 (26%), Positives = 127/305 (41%), Gaps = 38/305 (12%)
Query: 137 LQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTS-FMLRAAAILSRDRLLP 195
L V+ VG +SL L + + R L RN IH NL + F+ ++ D+
Sbjct: 860 LSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDK--- 916
Query: 196 RPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGH 255
Q AC + Y A ++WL +EGV+L+ LLV V SE
Sbjct: 917 --------------TQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSR 962
Query: 256 FRYYLLLGWGAPALFVIPWVIVRYLYENTQ--CWERNEVKAIWWIIRTPILMTILINFLI 313
+YY L G+ PAL V + Y T+ CW R + IW I P+ I++N +
Sbjct: 963 TKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFI-GPVSFVIVVNLVF 1021
Query: 314 FIRILGILL---SKLRTRQMRCRDYRLRLARSTLTLVPLLGV---HEVVFAPVTEEQARG 367
+ L ++ S L+ R + + A + L+ LLG+ ++F + +E
Sbjct: 1022 LMVTLHKMIRSSSVLKPDSSRLDNIK-SWALGAIALLFLLGLTWAFGLLF--INKESVVM 1078
Query: 368 ALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHH--CRLRRSLGEEQRQLPE 425
A F ++FQG + V +C + K+V E + H C +R G L
Sbjct: 1079 AYLFTT------FNAFQGVFIFVFHCALQKKVHKEYSKCLRHSYCCIRSPPGGTHGSLKT 1132
Query: 426 RAFRA 430
A R+
Sbjct: 1133 SAMRS 1137
>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
Length = 1469
Score = 70.5 bits (171), Expect = 3e-12
Identities = 81/305 (26%), Positives = 127/305 (41%), Gaps = 38/305 (12%)
Query: 137 LQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTS-FMLRAAAILSRDRLLP 195
L V+ VG +SL L + + R L RN IH NL + F+ ++ D+
Sbjct: 855 LSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDK--- 911
Query: 196 RPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGH 255
Q AC + Y A ++WL +EGV+L+ LLV V SE
Sbjct: 912 --------------TQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSR 957
Query: 256 FRYYLLLGWGAPALFVIPWVIVRYLYENTQ--CWERNEVKAIWWIIRTPILMTILINFLI 313
+YY L G+ PAL V + Y T+ CW R + IW I P+ I++N +
Sbjct: 958 TKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFI-GPVSFVIVVNLVF 1016
Query: 314 FIRILGILL---SKLRTRQMRCRDYRLRLARSTLTLVPLLGV---HEVVFAPVTEEQARG 367
+ L ++ S L+ R + + A + L+ LLG+ ++F + +E
Sbjct: 1017 LMVTLHKMIRSSSVLKPDSSRLDNIK-SWALGAIALLFLLGLTWAFGLLF--INKESVVM 1073
Query: 368 ALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHH--CRLRRSLGEEQRQLPE 425
A F ++FQG + V +C + K+V E + H C +R G L
Sbjct: 1074 AYLFTT------FNAFQGVFIFVFHCALQKKVHKEYSKCLRHSYCCIRSPPGGTHGSLKT 1127
Query: 426 RAFRA 430
A R+
Sbjct: 1128 SAMRS 1132
>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
Length = 786
Score = 69.3 bits (168), Expect = 7e-12
Identities = 74/276 (26%), Positives = 127/276 (46%), Gaps = 28/276 (10%)
Query: 136 RLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLP 195
+L ++ VG +LSL LLL +L L R + +R IH++L + + L+ +
Sbjct: 497 KLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAG---IE 553
Query: 196 RPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGH 255
G +G CR + YC A + W+ +EG+ L+ L+V V +
Sbjct: 554 NEGGQVG-----------LRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLS 602
Query: 256 FRYYLLLGWGAPALFV-IPWVIVRYLYENTQ-CWERNEVKAIWWIIRTPILMTILINFLI 313
R+ L+G+G P L V + I Y + CW E + W P+ IL N +I
Sbjct: 603 TRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFE-QGFLWSFLGPVTFIILCNAVI 661
Query: 314 FIRILGILLSKLRTRQMRCRDYRLRLARS-TLTLVP---LLGVHEVVFAPVTEEQARGAL 369
F+ + L K ++ +L+ AR+ T+T + LLG V + ++++ L
Sbjct: 662 FVTTVWKLTQKF--SEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSL-VL 718
Query: 370 RFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRR 405
+ F I L+ QG + +L+C +NK+V+ E R+
Sbjct: 719 TYV---FTI-LNCLQGAFLYLLHCLLNKKVREEYRK 750
>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
Length = 742
Score = 69.3 bits (168), Expect = 7e-12
Identities = 74/276 (26%), Positives = 127/276 (46%), Gaps = 28/276 (10%)
Query: 136 RLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLP 195
+L ++ VG +LSL LLL +L L R + +R IH++L + + L+ +
Sbjct: 453 KLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAG---IE 509
Query: 196 RPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGH 255
G +G CR + YC A + W+ +EG+ L+ L+V V +
Sbjct: 510 NEGGQVG-----------LRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLS 558
Query: 256 FRYYLLLGWGAPALFV-IPWVIVRYLYENTQ-CWERNEVKAIWWIIRTPILMTILINFLI 313
R+ L+G+G P L V + I Y + CW E + W P+ IL N +I
Sbjct: 559 TRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFE-QGFLWSFLGPVTFIILCNAVI 617
Query: 314 FIRILGILLSKLRTRQMRCRDYRLRLARS-TLTLVP---LLGVHEVVFAPVTEEQARGAL 369
F+ + L K ++ +L+ AR+ T+T + LLG V + ++++ L
Sbjct: 618 FVTTVWKLTQKF--SEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSL-VL 674
Query: 370 RFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRR 405
+ F I L+ QG + +L+C +NK+V+ E R+
Sbjct: 675 TYV---FTI-LNCLQGAFLYLLHCLLNKKVREEYRK 706
>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
Length = 835
Score = 69.3 bits (168), Expect = 7e-12
Identities = 74/276 (26%), Positives = 127/276 (46%), Gaps = 28/276 (10%)
Query: 136 RLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLP 195
+L ++ VG +LSL LLL +L L R + +R IH++L + + L+ +
Sbjct: 546 KLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAG---IE 602
Query: 196 RPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGH 255
G +G CR + YC A + W+ +EG+ L+ L+V V +
Sbjct: 603 NEGGQVG-----------LRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLS 651
Query: 256 FRYYLLLGWGAPALFV-IPWVIVRYLYENTQ-CWERNEVKAIWWIIRTPILMTILINFLI 313
R+ L+G+G P L V + I Y + CW E + W P+ IL N +I
Sbjct: 652 TRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFE-QGFLWSFLGPVTFIILCNAVI 710
Query: 314 FIRILGILLSKLRTRQMRCRDYRLRLARS-TLTLVP---LLGVHEVVFAPVTEEQARGAL 369
F+ + L K ++ +L+ AR+ T+T + LLG V + ++++ L
Sbjct: 711 FVTTVWKLTQKF--SEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSL-VL 767
Query: 370 RFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRR 405
+ F I L+ QG + +L+C +NK+V+ E R+
Sbjct: 768 TYV---FTI-LNCLQGAFLYLLHCLLNKKVREEYRK 799
>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
sapiens]
Length = 3312
Score = 67.8 bits (164), Expect = 2e-11
Identities = 86/340 (25%), Positives = 133/340 (39%), Gaps = 50/340 (14%)
Query: 102 QCGSDGQWGLWRDHTQCENPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSL 161
+C G +G+ D + E E + LE L V V ++S+A L+L IL
Sbjct: 2513 RCSRTGTFGVLMDASPRERLEGD---------LELLAVFTHVVVAVSVAALVLTAAILLS 2563
Query: 162 FRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQI 221
R L IH N+ AA L LL G + L C I
Sbjct: 2564 LRSLKSNVRGIHANV--------AAALGVAELLFLLGIHRTHNQLV--------CTAVAI 2607
Query: 222 VTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFV-IPWVIVRYL 280
+ Y + + WL V+G++L+ + V + G R+Y LGWG PA+ + + +
Sbjct: 2608 LLHYFFLSTFAWLFVQGLHLYRMQVEPRNVDRGAMRFYHALGWGVPAVLLGLAVGLDPEG 2667
Query: 281 YENTQ-CWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRL 339
Y N CW I W P+++ I++N +F+ S T Q +
Sbjct: 2668 YGNPDFCWISVHEPLI-WSFAGPVVLVIVMNGTMFLLAARTSCS---TGQREAKKTSALT 2723
Query: 340 ARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEV 399
RS+ L+ L+ +F + + A + G L QG V +L+C +N
Sbjct: 2724 LRSSFLLLLLVSA-SWLFGLLAVNHSILAFHYLHAG----LCGLQGLAVLLLFCVLN--- 2775
Query: 400 QSEIRRGW-HHCRLRRSLGEEQRQLPERAFRALPSGSGPG 438
++ R W C R++ EE R P G GPG
Sbjct: 2776 -ADARAAWMPACLGRKAAPEEARPAP---------GLGPG 2805
>gi|6912464 latrophilin 2 precursor [Homo sapiens]
Length = 1403
Score = 63.5 bits (153), Expect = 4e-10
Identities = 70/283 (24%), Positives = 117/283 (41%), Gaps = 38/283 (13%)
Query: 137 LQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTS-FMLRAAAILSRDRLLP 195
L V+ VG +SL L + + FR L RN IH NL + F+ ++ D+
Sbjct: 834 LTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDK--- 890
Query: 196 RPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGH 255
+ AC + + A + W+ +EGV L+ +LV V SE
Sbjct: 891 --------------TKYAIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSR 936
Query: 256 FRYYLLLGWGAPALFVIPWVIVRYLYENTQ--CWERNEVKAIWWIIRTPILMTILINFLI 313
+YY + G+ PA V + Y T+ CW + IW I P+ IL+N +
Sbjct: 937 KKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFI-GPVTFIILLNIIF 995
Query: 314 FIRILGILLSKLRTRQMRCRDYRLRLARS----TLTLVPLLGV---HEVVFAPVTEEQAR 366
+ L ++ T ++ RL +S L+ LLG+ ++F + EE
Sbjct: 996 LVITLCKMVKHSNT--LKPDSSRLENIKSWVLGAFALLCLLGLTWSFGLLF--INEETIV 1051
Query: 367 GALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHH 409
A F ++FQG + + +C + K+V+ E + + H
Sbjct: 1052 MAYLFT------IFNAFQGVFIFIFHCALQKKVRKEYGKCFRH 1088
>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
sapiens]
Length = 652
Score = 63.2 bits (152), Expect = 5e-10
Identities = 78/329 (23%), Positives = 132/329 (40%), Gaps = 54/329 (16%)
Query: 137 LQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINL-FTSFMLRAAAILSRDRLLP 195
L V+ VG S+SL LLLA L L + + T +H+ L F+ ++ DR P
Sbjct: 356 LTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFLAHLLFLVGIDRTEP 415
Query: 196 RPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSL---LVLVGGSE 252
+ C Y A +TW+L+EGV+L L +V S
Sbjct: 416 K-----------------VLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSS 458
Query: 253 EGHFRYYLL--LGWGAPALFV-IPWVIVRYLYENT-QCWERNEVKAIWWIIRTPILMTIL 308
+++ +G+G PA+ V I +LY +CW + + W P+
Sbjct: 459 INRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLD-QGFMWSFLGPVCAIFS 517
Query: 309 INFLIFIRILGIL---LSKLRTRQMRCRDYRLRLARSTLTLVPL-----LGVHEVVFAPV 360
N ++FI + IL LS L + ++ R+ ++T L L LG+ +V P
Sbjct: 518 ANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQV--GPA 575
Query: 361 TEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQ 420
+ A ++S QGF + ++YC ++++VQ + ++ + +S E
Sbjct: 576 AQVMAY---------LFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKSESETY 626
Query: 421 RQLPERAFRALPSGSGPGEVPTSRGLSSG 449
L S GP P+ + G
Sbjct: 627 ---------TLSSKMGPDSKPSEGDVFPG 646
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.140 0.453
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,362,278
Number of Sequences: 37866
Number of extensions: 829667
Number of successful extensions: 3246
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 3053
Number of HSP's gapped (non-prelim): 98
length of query: 466
length of database: 18,247,518
effective HSP length: 106
effective length of query: 360
effective length of database: 14,233,722
effective search space: 5124139920
effective search space used: 5124139920
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.