Search of human proteins with 4503561

Search of human proteins with 4503561

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503561 epithelial membrane protein 2 [Homo sapiens]
         (167 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503561 epithelial membrane protein 2 [Homo sapiens]               339   7e-94
gi|239747698 PREDICTED: similar to hCG1784039 [Homo sapiens]          184   3e-47
gi|4505907 peripheral myelin protein 22 [Homo sapiens]                132   1e-31
gi|24430165 peripheral myelin protein 22 [Homo sapiens]               132   1e-31
gi|24430163 peripheral myelin protein 22 [Homo sapiens]               132   1e-31
gi|4503563 epithelial membrane protein 3 [Homo sapiens]               121   3e-28
gi|4503559 epithelial membrane protein 1 [Homo sapiens]               121   3e-28
gi|169163665 PREDICTED: similar to hCG1784039 [Homo sapiens]           91   6e-19
gi|169163222 PREDICTED: hypothetical protein LOC391359 [Homo sap...    91   6e-19
gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2 ...    45   3e-05
gi|10863887 claudin 1 [Homo sapiens]                                   44   8e-05
gi|50345279 claudin 18 isoform 2 [Homo sapiens]                        37   0.006
gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1 [...    37   0.008
gi|7705961 claudin 18 isoform 1 [Homo sapiens]                         37   0.008
gi|5921465 claudin 10 isoform b [Homo sapiens]                         36   0.013
gi|46395496 G protein-coupled receptor for asthma susceptibility...    35   0.023
gi|46391085 G protein-coupled receptor for asthma susceptibility...    35   0.023
gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens]       34   0.067
gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo...    34   0.067
gi|226437592 transmembrane protein 114 [Homo sapiens]                  34   0.067
gi|93588657 claudin domain containing 1 protein isoform d [Homo ...    33   0.11 
gi|93588650 claudin domain containing 1 protein isoform a [Homo ...    33   0.11 
gi|93588620 claudin domain containing 1 protein isoform b [Homo ...    33   0.11 
gi|93588614 claudin domain containing 1 protein isoform a [Homo ...    33   0.11 
gi|93588624 claudin domain containing 1 protein isoform a [Homo ...    33   0.11 
gi|11096340 claudin domain containing 1 protein isoform a [Homo ...    33   0.11 
gi|33598916 claudin 10 isoform a [Homo sapiens]                        32   0.33 
gi|5031627 chemokine (C-C motif) receptor 4 [Homo sapiens]             31   0.43 
gi|22748765 claudin domain containing 2 [Homo sapiens]                 31   0.43 
gi|157951718 GSG1-like isoform 1 [Homo sapiens]                        30   0.96 

>gi|4503561 epithelial membrane protein 2 [Homo sapiens]
          Length = 167

 Score =  339 bits (869), Expect = 7e-94
 Identities = 167/167 (100%), Positives = 167/167 (100%)

Query: 1   MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTVINDSFQEYST 60
           MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTVINDSFQEYST
Sbjct: 1   MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTVINDSFQEYST 60

Query: 61  LQAVQATMILSTILCCIAFFIFVLQLFRLKQGERFVLTSIIQLMSCLCVMIAASIYTDRR 120
           LQAVQATMILSTILCCIAFFIFVLQLFRLKQGERFVLTSIIQLMSCLCVMIAASIYTDRR
Sbjct: 61  LQAVQATMILSTILCCIAFFIFVLQLFRLKQGERFVLTSIIQLMSCLCVMIAASIYTDRR 120

Query: 121 EDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLILRKRK 167
           EDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLILRKRK
Sbjct: 121 EDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLILRKRK 167


>gi|239747698 PREDICTED: similar to hCG1784039 [Homo sapiens]
          Length = 161

 Score =  184 bits (467), Expect = 3e-47
 Identities = 101/167 (60%), Positives = 120/167 (71%), Gaps = 16/167 (9%)

Query: 1   MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTVINDSFQEYST 60
           MLVLL F +AFHITSAALLFIAT+DNAWWVG+EFFADVWRICT NT CTVINDSF+EYS 
Sbjct: 1   MLVLLTFTVAFHITSAALLFIATIDNAWWVGNEFFADVWRICTKNTKCTVINDSFKEYSM 60

Query: 61  LQAVQATMILSTILCCIAFFIFVLQLFRLKQGERFVLTSIIQL-----MSCLCVMIAASI 115
            +A   T ++  +    A  +   ++          L +I++L     MS LC+MIAASI
Sbjct: 61  GRARWLTPVIPALWEAEACGLXGQEI-------ETSLANIMKLLHHATMSYLCLMIAASI 113

Query: 116 YTDRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLI 162
           YTDRR++  D    FY +T+EGSYGYSYILAWVAFA TFIS MMYLI
Sbjct: 114 YTDRRDETTD----FYYLTKEGSYGYSYILAWVAFAFTFISSMMYLI 156


>gi|4505907 peripheral myelin protein 22 [Homo sapiens]
          Length = 160

 Score =  132 bits (332), Expect = 1e-31
 Identities = 73/170 (42%), Positives = 108/170 (63%), Gaps = 13/170 (7%)

Query: 1   MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTV---INDSFQE 57
           ML+LL  II  H+    LLF++T+ + W VG+    D+W+ C+ +++  V    + S  E
Sbjct: 1   MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNE 60

Query: 58  YSTLQAVQATMILSTILCCIAFFIFVLQLFRLKQGERFVLTSIIQLMSCLCVMIAASIYT 117
           +  LQ+VQATMILS I   ++ F+F  QLF L +G RF +T I Q+++ LCVM AA+IYT
Sbjct: 61  W--LQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYT 118

Query: 118 DRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLILRKRK 167
            R  + H        +  + SYG++YILAWVAF    +SG++Y+ILRKR+
Sbjct: 119 VRHPEWH--------LNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE 160


>gi|24430165 peripheral myelin protein 22 [Homo sapiens]
          Length = 160

 Score =  132 bits (332), Expect = 1e-31
 Identities = 73/170 (42%), Positives = 108/170 (63%), Gaps = 13/170 (7%)

Query: 1   MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTV---INDSFQE 57
           ML+LL  II  H+    LLF++T+ + W VG+    D+W+ C+ +++  V    + S  E
Sbjct: 1   MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNE 60

Query: 58  YSTLQAVQATMILSTILCCIAFFIFVLQLFRLKQGERFVLTSIIQLMSCLCVMIAASIYT 117
           +  LQ+VQATMILS I   ++ F+F  QLF L +G RF +T I Q+++ LCVM AA+IYT
Sbjct: 61  W--LQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYT 118

Query: 118 DRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLILRKRK 167
            R  + H        +  + SYG++YILAWVAF    +SG++Y+ILRKR+
Sbjct: 119 VRHPEWH--------LNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE 160


>gi|24430163 peripheral myelin protein 22 [Homo sapiens]
          Length = 160

 Score =  132 bits (332), Expect = 1e-31
 Identities = 73/170 (42%), Positives = 108/170 (63%), Gaps = 13/170 (7%)

Query: 1   MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTV---INDSFQE 57
           ML+LL  II  H+    LLF++T+ + W VG+    D+W+ C+ +++  V    + S  E
Sbjct: 1   MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNE 60

Query: 58  YSTLQAVQATMILSTILCCIAFFIFVLQLFRLKQGERFVLTSIIQLMSCLCVMIAASIYT 117
           +  LQ+VQATMILS I   ++ F+F  QLF L +G RF +T I Q+++ LCVM AA+IYT
Sbjct: 61  W--LQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYT 118

Query: 118 DRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLILRKRK 167
            R  + H        +  + SYG++YILAWVAF    +SG++Y+ILRKR+
Sbjct: 119 VRHPEWH--------LNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE 160


>gi|4503563 epithelial membrane protein 3 [Homo sapiens]
          Length = 163

 Score =  121 bits (303), Expect = 3e-28
 Identities = 68/170 (40%), Positives = 99/170 (58%), Gaps = 10/170 (5%)

Query: 1   MLVLLAFIIAFHITSAALLFIATVDNAWWV--GDEFFADVWRICT-NNTNCTVINDSFQE 57
           M +LL  + A HI    LLF+AT+D +WW   G E   ++W  CT NN   T    +  E
Sbjct: 1   MSLLLLVVSALHILILILLFVATLDKSWWTLPGKESL-NLWYDCTWNNDTKTWACSNVSE 59

Query: 58  YSTLQAVQATMILSTILCCIAFFIFVLQLFRLKQGERFVLTSIIQLMSCLCVMIAASIYT 117
              L+AVQ  M+LS ILCC++F +F+ QL+ +++G  F  T + QL + + V   A IY 
Sbjct: 60  NGWLKAVQVLMVLSLILCCLSFILFMFQLYTMRRGGLFYATGLCQLCTSVAVFTGALIYA 119

Query: 118 DRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLILRKRK 167
              E+I +K+       R GS+GY + LAWVAF    +SG++Y+ LRKR+
Sbjct: 120 IHAEEILEKH------PRGGSFGYCFALAWVAFPLALVSGIIYIHLRKRE 163


>gi|4503559 epithelial membrane protein 1 [Homo sapiens]
          Length = 157

 Score =  121 bits (303), Expect = 3e-28
 Identities = 68/171 (39%), Positives = 98/171 (57%), Gaps = 19/171 (11%)

Query: 1   MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADV--WRICTNNTNCTVINDSFQEY 58
           MLVLLA I   HI +  +LF++T+ N W V +   A V  W+ CTN +    +  S+   
Sbjct: 1   MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCTNISCSDSL--SYASE 58

Query: 59  STLQAVQATMILSTILCCIAFFIFVLQLFRLKQGERFVLTSIIQLMSCLCVMIAASIYTD 118
             L+ VQA MILS I C IA  +FV QLF +++G RF L+    L+  LC+++  SIYT 
Sbjct: 59  DALKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYTS 118

Query: 119 RREDIHDKNAKFYPVTREGS---YGYSYILAWVAFACTFISGMMYLILRKR 166
                       +   R+G+   +GYSYIL W+ F  +FI G++YL+LRK+
Sbjct: 119 ------------HYANRDGTQYHHGYSYILGWICFCFSFIIGVLYLVLRKK 157


>gi|169163665 PREDICTED: similar to hCG1784039 [Homo sapiens]
          Length = 93

 Score = 90.5 bits (223), Expect = 6e-19
 Identities = 40/46 (86%), Positives = 43/46 (93%)

Query: 1  MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNT 46
          MLVLL F +AFHITSAALLFIAT+DNAWWVG+EFFADVWRICT NT
Sbjct: 1  MLVLLTFTVAFHITSAALLFIATIDNAWWVGNEFFADVWRICTKNT 46



 Score = 63.5 bits (153), Expect = 8e-11
 Identities = 29/38 (76%), Positives = 32/38 (84%)

Query: 125 DKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLI 162
           D+   FY +T+EGSYGYSYILAWVAFA TFIS MMYLI
Sbjct: 51  DETTDFYYLTKEGSYGYSYILAWVAFAFTFISSMMYLI 88


>gi|169163222 PREDICTED: hypothetical protein LOC391359 [Homo
          sapiens]
          Length = 93

 Score = 90.5 bits (223), Expect = 6e-19
 Identities = 40/46 (86%), Positives = 43/46 (93%)

Query: 1  MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNT 46
          MLVLL F +AFHITSAALLFIAT+DNAWWVG+EFFADVWRICT NT
Sbjct: 1  MLVLLTFTVAFHITSAALLFIATIDNAWWVGNEFFADVWRICTKNT 46



 Score = 63.5 bits (153), Expect = 8e-11
 Identities = 29/38 (76%), Positives = 32/38 (84%)

Query: 125 DKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLI 162
           D+   FY +T+EGSYGYSYILAWVAFA TFIS MMYLI
Sbjct: 51  DETTDFYYLTKEGSYGYSYILAWVAFAFTFISSMMYLI 88


>gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2
           [Homo sapiens]
          Length = 173

 Score = 45.1 bits (105), Expect = 3e-05
 Identities = 43/152 (28%), Positives = 64/152 (42%), Gaps = 19/152 (12%)

Query: 18  LLFIATVDNAWWV----GDEFFADVWRICTNNTNCTVINDSFQEYSTLQAVQATMILSTI 73
           LL +A   + W      G      +WR C  N  C +  DS   ++   A +A MILS  
Sbjct: 18  LLVVAMATDHWMQYRLSGSFAHQGLWRYCLGN-KCYLQTDSIAYWN---ATRAFMILSA- 72

Query: 74  LCCIAFFIFVLQLFR----LKQGERFVLTSIIQLMSCLCVMIAASIYTDRREDIHDKNAK 129
           LC I+  I  +  F       +  R     I+   S L V++A +IYT        +   
Sbjct: 73  LCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIYTGVTVSFLGRRFG 132

Query: 130 FYPVTREGSYGYSYILAWVAFACTFISGMMYL 161
                 +  + +SYIL WVA   TF +G+ Y+
Sbjct: 133 ------DWRFSWSYILGWVAVLMTFFAGIFYM 158


>gi|10863887 claudin 1 [Homo sapiens]
          Length = 211

 Score = 43.5 bits (101), Expect = 8e-05
 Identities = 45/189 (23%), Positives = 78/189 (41%), Gaps = 28/189 (14%)

Query: 2   LVLLAFIIAFHITSAALLFIATVDNAW----WVGDEF------FADVWRIC----TNNTN 47
           L LL FI+AF     A+  ++T    W    + GD        +  +W  C    T    
Sbjct: 6   LQLLGFILAFLGWIGAI--VSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQ 63

Query: 48  CTVINDSFQEYSTLQAVQATMILSTILCCIAFFIFVLQLFRLK--------QGERFVLTS 99
           C V +      STLQA +A M++  +L  IA F+  + +  +K        +    V+  
Sbjct: 64  CKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGG 123

Query: 100 IIQLMSCLCVMIAASIYTDR-REDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFISGM 158
            I L++ L +++A + Y +R  ++ +D      PV     +G +    W A +   + G 
Sbjct: 124 AIFLLAGLAILVATAWYGNRIVQEFYD---PMTPVNARYEFGQALFTGWAAASLCLLGGA 180

Query: 159 MYLILRKRK 167
           +      RK
Sbjct: 181 LLCCSCPRK 189


>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
          Length = 261

 Score = 37.4 bits (85), Expect = 0.006
 Identities = 46/188 (24%), Positives = 74/188 (39%), Gaps = 32/188 (17%)

Query: 5   LAFIIAFHITSAALLFIATVDNAWWVGDEF---------FADVWRICTNN----TNCTVI 51
           L F+++  +   A +  AT  + W   D +         +  +WR C       T C   
Sbjct: 9   LGFVVS--LIGIAGIIAATCMDQWSTQDLYNNPVTAVFNYQGLWRSCVRESSGFTECRGY 66

Query: 52  NDSFQEYSTLQAVQATMILSTILCCIAFF--IFVLQLFRLKQGE-----RFVLTS-IIQL 103
                  + LQAV+A MI+  +L  I     IF L+  R+   E        LTS I+ +
Sbjct: 67  FTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFI 126

Query: 104 MSCLCVMIAASIYTDRR-EDIHDKNAKFYP--------VTREGSYGYSYILAWVAFACTF 154
           +S LC +   S++ +    +     A  Y         V    ++G +  + WVA   T 
Sbjct: 127 VSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGLTL 186

Query: 155 ISGMMYLI 162
           I G+M  I
Sbjct: 187 IGGVMMCI 194


>gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1
           [Homo sapiens]
          Length = 215

 Score = 37.0 bits (84), Expect = 0.008
 Identities = 31/103 (30%), Positives = 46/103 (44%), Gaps = 11/103 (10%)

Query: 63  AVQATMILSTILCCIAFFIFVLQLFR----LKQGERFVLTSIIQLMSCLCVMIAASIYTD 118
           A +A MILS  LC I+  I  +  F       +  R     I+   S L V++A +IYT 
Sbjct: 105 ATRAFMILSA-LCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIYTG 163

Query: 119 RREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYL 161
                  +         +  + +SYIL WVA   TF +G+ Y+
Sbjct: 164 VTVSFLGRRFG------DWRFSWSYILGWVAVLMTFFAGIFYM 200


>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
          Length = 261

 Score = 37.0 bits (84), Expect = 0.008
 Identities = 39/149 (26%), Positives = 60/149 (40%), Gaps = 21/149 (14%)

Query: 35  FADVWRICTNN----TNCTVINDSFQEYSTLQAVQATMILSTILCCIAFF--IFVLQLFR 88
           +  +WR C       T C          + LQAV+A MI+  +L  I     IF L+  R
Sbjct: 46  YEGLWRSCVRQSSGFTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIR 105

Query: 89  LKQGE-----RFVLTS-IIQLMSCLCVMIAASIYTDRR-EDIHDKNAKFYP--------V 133
           +   E        LTS I+ ++S LC +   S++ +    +     A  Y         V
Sbjct: 106 IGSMEDSAKANMTLTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTV 165

Query: 134 TREGSYGYSYILAWVAFACTFISGMMYLI 162
               ++G +  + WVA   T I G+M  I
Sbjct: 166 QTRYTFGAALFVGWVAGGLTLIGGVMMCI 194


>gi|5921465 claudin 10 isoform b [Homo sapiens]
          Length = 228

 Score = 36.2 bits (82), Expect = 0.013
 Identities = 34/156 (21%), Positives = 63/156 (40%), Gaps = 24/156 (15%)

Query: 21  IATVDNAWWVGDEFFADVWRIC----TNNTNCTVINDSFQEYSTLQAVQATMILSTILCC 76
           ++T+D        ++A++W+ C    T  +NC            +QA +  MI +  L  
Sbjct: 32  VSTIDGTVITTATYWANLWKACVTDSTGVSNCKDFPSMLALDGYIQACRGLMIAAVSL-- 89

Query: 77  IAFFIFVLQLFRLK----------QGERFVLTSIIQLMSCLCVMIAASIYTDRREDIHDK 126
             FF  +  LF +K          + +   L  I+ ++S LC M   S+Y ++       
Sbjct: 90  -GFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANK-----IT 143

Query: 127 NAKFYPVTREGSY--GYSYILAWVAFACTFISGMMY 160
              F P+  E  Y  G +  + W   +   I G+++
Sbjct: 144 TEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIF 179


>gi|46395496 G protein-coupled receptor for asthma susceptibility
           isoform A [Homo sapiens]
          Length = 371

 Score = 35.4 bits (80), Expect = 0.023
 Identities = 29/120 (24%), Positives = 55/120 (45%), Gaps = 5/120 (4%)

Query: 2   LVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTVINDSFQEYSTL 61
           + ++AF++ F   +   +    V    W+  + +  V   C++   C+  N      + +
Sbjct: 211 MTIVAFLVYFIPLTIISIMYGIVIRTIWIKSKTYETVISNCSDGKLCSSYNRGLISKAKI 270

Query: 62  QAVQAT--MILSTILCCIAFFIF-VLQLFRL--KQGERFVLTSIIQLMSCLCVMIAASIY 116
           +A++ +  +IL+ I C   +F+F +L  F L     ERF  + IIQ +  L   I   IY
Sbjct: 271 KAIKYSIIIILAFICCWSPYFLFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIY 330


>gi|46391085 G protein-coupled receptor for asthma susceptibility
           isoform B [Homo sapiens]
          Length = 377

 Score = 35.4 bits (80), Expect = 0.023
 Identities = 29/120 (24%), Positives = 55/120 (45%), Gaps = 5/120 (4%)

Query: 2   LVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTVINDSFQEYSTL 61
           + ++AF++ F   +   +    V    W+  + +  V   C++   C+  N      + +
Sbjct: 211 MTIVAFLVYFIPLTIISIMYGIVIRTIWIKSKTYETVISNCSDGKLCSSYNRGLISKAKI 270

Query: 62  QAVQAT--MILSTILCCIAFFIF-VLQLFRL--KQGERFVLTSIIQLMSCLCVMIAASIY 116
           +A++ +  +IL+ I C   +F+F +L  F L     ERF  + IIQ +  L   I   IY
Sbjct: 271 KAIKYSIIIILAFICCWSPYFLFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIY 330


>gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens]
          Length = 223

 Score = 33.9 bits (76), Expect = 0.067
 Identities = 33/145 (22%), Positives = 59/145 (40%), Gaps = 26/145 (17%)

Query: 38  VWRICTNNTNCT-----------VINDSFQEYSTLQAVQATMI-LSTILCCIA----FFI 81
           +WR C   + CT            +++S ++  T+      ++ LS IL        F  
Sbjct: 68  LWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS 127

Query: 82  FVLQLFRLKQGERFVLTSIIQLMSCLCVMIAASIYTDR-----REDIHDKNAKFYPVTRE 136
           F+LQ + L      +LT I+ L   +  +   S+Y        RE +     K      +
Sbjct: 128 FLLQAYLL-----LLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVD 182

Query: 137 GSYGYSYILAWVAFACTFISGMMYL 161
            S+G+S  L W++F    ++G  +L
Sbjct: 183 ISFGWSLALGWISFIAELLTGAAFL 207


>gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo
           sapiens]
          Length = 217

 Score = 33.9 bits (76), Expect = 0.067
 Identities = 33/145 (22%), Positives = 59/145 (40%), Gaps = 26/145 (17%)

Query: 38  VWRICTNNTNCT-----------VINDSFQEYSTLQAVQATMI-LSTILCCIA----FFI 81
           +WR C   + CT            +++S ++  T+      ++ LS IL        F  
Sbjct: 62  LWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS 121

Query: 82  FVLQLFRLKQGERFVLTSIIQLMSCLCVMIAASIYTDR-----REDIHDKNAKFYPVTRE 136
           F+LQ + L      +LT I+ L   +  +   S+Y        RE +     K      +
Sbjct: 122 FLLQAYLL-----LLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVD 176

Query: 137 GSYGYSYILAWVAFACTFISGMMYL 161
            S+G+S  L W++F    ++G  +L
Sbjct: 177 ISFGWSLALGWISFIAELLTGAAFL 201


>gi|226437592 transmembrane protein 114 [Homo sapiens]
          Length = 223

 Score = 33.9 bits (76), Expect = 0.067
 Identities = 33/145 (22%), Positives = 59/145 (40%), Gaps = 26/145 (17%)

Query: 38  VWRICTNNTNCT-----------VINDSFQEYSTLQAVQATMI-LSTILCCIA----FFI 81
           +WR C   + CT            +++S ++  T+      ++ LS IL        F  
Sbjct: 68  LWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS 127

Query: 82  FVLQLFRLKQGERFVLTSIIQLMSCLCVMIAASIYTDR-----REDIHDKNAKFYPVTRE 136
           F+LQ + L      +LT I+ L   +  +   S+Y        RE +     K      +
Sbjct: 128 FLLQAYLL-----LLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVD 182

Query: 137 GSYGYSYILAWVAFACTFISGMMYL 161
            S+G+S  L W++F    ++G  +L
Sbjct: 183 ISFGWSLALGWISFIAELLTGAAFL 207


>gi|93588657 claudin domain containing 1 protein isoform d [Homo
           sapiens]
          Length = 158

 Score = 33.1 bits (74), Expect = 0.11
 Identities = 18/66 (27%), Positives = 34/66 (51%), Gaps = 2/66 (3%)

Query: 96  VLTSIIQLMSCLCVMIAASIYTDRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFI 155
           + T I+ L++ LC + + S Y    E +H K     P    G +G+S+ LA V+    F+
Sbjct: 76  IATGILHLLAGLCTLGSVSCYVAGIELLHQKLE--LPDNVSGEFGWSFCLACVSAPLQFM 133

Query: 156 SGMMYL 161
           +  +++
Sbjct: 134 ASALFI 139


>gi|93588650 claudin domain containing 1 protein isoform a [Homo
           sapiens]
          Length = 253

 Score = 33.1 bits (74), Expect = 0.11
 Identities = 18/66 (27%), Positives = 34/66 (51%), Gaps = 2/66 (3%)

Query: 96  VLTSIIQLMSCLCVMIAASIYTDRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFI 155
           + T I+ L++ LC + + S Y    E +H K     P    G +G+S+ LA V+    F+
Sbjct: 171 IATGILHLLAGLCTLGSVSCYVAGIELLHQKLE--LPDNVSGEFGWSFCLACVSAPLQFM 228

Query: 156 SGMMYL 161
           +  +++
Sbjct: 229 ASALFI 234


>gi|93588620 claudin domain containing 1 protein isoform b [Homo
           sapiens]
          Length = 276

 Score = 33.1 bits (74), Expect = 0.11
 Identities = 18/66 (27%), Positives = 34/66 (51%), Gaps = 2/66 (3%)

Query: 96  VLTSIIQLMSCLCVMIAASIYTDRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFI 155
           + T I+ L++ LC + + S Y    E +H K     P    G +G+S+ LA V+    F+
Sbjct: 194 IATGILHLLAGLCTLGSVSCYVAGIELLHQKLE--LPDNVSGEFGWSFCLACVSAPLQFM 251

Query: 156 SGMMYL 161
           +  +++
Sbjct: 252 ASALFI 257


>gi|93588614 claudin domain containing 1 protein isoform a [Homo
           sapiens]
          Length = 253

 Score = 33.1 bits (74), Expect = 0.11
 Identities = 18/66 (27%), Positives = 34/66 (51%), Gaps = 2/66 (3%)

Query: 96  VLTSIIQLMSCLCVMIAASIYTDRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFI 155
           + T I+ L++ LC + + S Y    E +H K     P    G +G+S+ LA V+    F+
Sbjct: 171 IATGILHLLAGLCTLGSVSCYVAGIELLHQKLE--LPDNVSGEFGWSFCLACVSAPLQFM 228

Query: 156 SGMMYL 161
           +  +++
Sbjct: 229 ASALFI 234


>gi|93588624 claudin domain containing 1 protein isoform a [Homo
           sapiens]
          Length = 253

 Score = 33.1 bits (74), Expect = 0.11
 Identities = 18/66 (27%), Positives = 34/66 (51%), Gaps = 2/66 (3%)

Query: 96  VLTSIIQLMSCLCVMIAASIYTDRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFI 155
           + T I+ L++ LC + + S Y    E +H K     P    G +G+S+ LA V+    F+
Sbjct: 171 IATGILHLLAGLCTLGSVSCYVAGIELLHQKLE--LPDNVSGEFGWSFCLACVSAPLQFM 228

Query: 156 SGMMYL 161
           +  +++
Sbjct: 229 ASALFI 234


>gi|11096340 claudin domain containing 1 protein isoform a [Homo
           sapiens]
          Length = 253

 Score = 33.1 bits (74), Expect = 0.11
 Identities = 18/66 (27%), Positives = 34/66 (51%), Gaps = 2/66 (3%)

Query: 96  VLTSIIQLMSCLCVMIAASIYTDRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFI 155
           + T I+ L++ LC + + S Y    E +H K     P    G +G+S+ LA V+    F+
Sbjct: 171 IATGILHLLAGLCTLGSVSCYVAGIELLHQKLE--LPDNVSGEFGWSFCLACVSAPLQFM 228

Query: 156 SGMMYL 161
           +  +++
Sbjct: 229 ASALFI 234


>gi|33598916 claudin 10 isoform a [Homo sapiens]
          Length = 226

 Score = 31.6 bits (70), Expect = 0.33
 Identities = 35/155 (22%), Positives = 61/155 (39%), Gaps = 28/155 (18%)

Query: 22  ATVDNAWWVGDEFFADVWRICTNNT----NCTVINDSFQEYSTLQAVQATMILSTILCCI 77
           ++V  A WV    +  +W  C  N     +C      F+    +QA +  MI +  L   
Sbjct: 35  SSVITATWV----YQGLWMNCAGNALGSFHCRPHFTIFKVAGYIQACRGLMIAAVSL--- 87

Query: 78  AFFIFVLQLFRLK----------QGERFVLTSIIQLMSCLCVMIAASIYTDRREDIHDKN 127
            FF  +  LF +K          + +   L  I+ ++S LC M   S+Y ++        
Sbjct: 88  GFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANK-----ITT 142

Query: 128 AKFYPVTREGSY--GYSYILAWVAFACTFISGMMY 160
             F P+  E  Y  G +  + W   +   I G+++
Sbjct: 143 EFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIF 177


>gi|5031627 chemokine (C-C motif) receptor 4 [Homo sapiens]
          Length = 360

 Score = 31.2 bits (69), Expect = 0.43
 Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 13/88 (14%)

Query: 50  VINDSFQEYSTLQAVQATMILSTILCC----IAFFI------FVLQLFRLKQGERFVLTS 99
           V+ D   E     A+QAT  L+ + CC    I FF+      ++LQLF+  +G  FVL  
Sbjct: 272 VLQDCTFERYLDYAIQATETLAFVHCCLNPIIYFFLGEKFRKYILQLFKTCRG-LFVLCQ 330

Query: 100 IIQLMSCLCVMIAASIYTDRR--EDIHD 125
              L+        +S YT      D+HD
Sbjct: 331 YCGLLQIYSADTPSSSYTQSTMDHDLHD 358


>gi|22748765 claudin domain containing 2 [Homo sapiens]
          Length = 167

 Score = 31.2 bits (69), Expect = 0.43
 Identities = 34/156 (21%), Positives = 63/156 (40%), Gaps = 20/156 (12%)

Query: 9   IAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTVINDSFQEYSTLQAVQATM 68
           I   + +  L+ ++T  N W    E  + +W+ C +      I  S    +TL    A M
Sbjct: 12  ILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECNHG-----ICSSIPCQTTLAVTVACM 66

Query: 69  ILSTILCCIAFFIFVLQLFRLKQGE--RFVLTSIIQLMSCLCVMIAASIYTDRREDIHDK 126
           +L+  +  +   + +    R  +GE  R   TS    +  L ++ A   YT +      K
Sbjct: 67  VLAVGVGVVGMVMGLR--IRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAW---K 121

Query: 127 NAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLI 162
           N  F+         +SY   W+A   + ++G  +L+
Sbjct: 122 NNVFF--------SWSYFSGWLALPFSILAGFCFLL 149


>gi|157951718 GSG1-like isoform 1 [Homo sapiens]
          Length = 331

 Score = 30.0 bits (66), Expect = 0.96
 Identities = 33/155 (21%), Positives = 56/155 (36%), Gaps = 24/155 (15%)

Query: 27  AWWVGDE------FFADVWRICTNNTN-----CTVIND--SFQEYSTLQAVQATMILSTI 73
           +W  GD+      F   +W  C    +     C    D     E   L     + +L  +
Sbjct: 88  SWETGDDRFLFRNFHTGIWYSCEEELSGLGEKCRSFIDLAPASEKGVLWLSVVSEVLYIL 147

Query: 74  LCCIAFFIFVLQLFRLKQ---GERF-VLTSIIQLMSCLCVMIAASIYTDRREDIHDKNAK 129
           L  + F +  L+LF       G +     ++  ++S L  M+A  +YT     +      
Sbjct: 148 LLVVGFSLMCLELFHSSNVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQ----VFQVTVS 203

Query: 130 FYPVT---REGSYGYSYILAWVAFACTFISGMMYL 161
             P         YG+S+ LAW +F C   + +  L
Sbjct: 204 LGPEDWRPHSWDYGWSFCLAWGSFTCCMAASVTTL 238


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.334    0.141    0.448 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,173,144
Number of Sequences: 37866
Number of extensions: 182093
Number of successful extensions: 686
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 651
Number of HSP's gapped (non-prelim): 41
length of query: 167
length of database: 18,247,518
effective HSP length: 95
effective length of query: 72
effective length of database: 14,650,248
effective search space: 1054817856
effective search space used: 1054817856
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.6 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.