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Search of human proteins with 4503413
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503413 heparin-binding EGF-like growth factor [Homo
sapiens]
(208 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503413 heparin-binding EGF-like growth factor [Homo sapiens] 423 e-119
gi|4502199 amphiregulin preproprotein [Homo sapiens] 82 3e-16
gi|113415639 PREDICTED: amphiregulin B [Homo sapiens] 82 3e-16
gi|4502461 betacellulin [Homo sapiens] 53 2e-07
gi|153791414 transforming growth factor, alpha isoform 2 [Homo s... 52 5e-07
gi|4507461 transforming growth factor, alpha isoform 1 [Homo sap... 52 5e-07
gi|12383051 transmembrane protein with EGF-like and two follista... 50 1e-06
gi|29568105 transmembrane protein with EGF-like and two follista... 49 4e-06
gi|61806622 epithelial mitogen [Homo sapiens] 46 2e-05
gi|236461846 neuregulin 1 isoform ndf43c [Homo sapiens] 44 1e-04
gi|7669526 neuregulin 1 isoform HRG-alpha [Homo sapiens] 44 1e-04
gi|7669520 neuregulin 1 isoform ndf43 [Homo sapiens] 44 1e-04
gi|4557567 epiregulin preproprotein [Homo sapiens] 42 5e-04
gi|166362728 epidermal growth factor (beta-urogastrone) [Homo sa... 41 8e-04
gi|20070380 neuregulin 4 [Homo sapiens] 39 0.003
gi|7669528 neuregulin 2 isoform 2 [Homo sapiens] 37 0.012
gi|7669532 neuregulin 2 isoform 4 [Homo sapiens] 37 0.012
gi|11321571 slit homolog 3 [Homo sapiens] 36 0.027
gi|126012573 low density lipoprotein-related protein 2 [Homo sap... 36 0.027
gi|24041035 notch 2 preproprotein [Homo sapiens] 34 0.077
gi|4758832 neuregulin 2 isoform 1 [Homo sapiens] 34 0.077
gi|222136611 poliovirus receptor-related 4 [Homo sapiens] 33 0.13
gi|7669530 neuregulin 2 isoform 3 [Homo sapiens] 33 0.13
gi|134244285 Notch homolog 3 [Homo sapiens] 33 0.22
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 33 0.22
gi|188528675 slit homolog 1 [Homo sapiens] 33 0.22
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 33 0.22
gi|116235485 delta-notch-like EGF repeat-containing transmembran... 33 0.22
gi|75709198 nephronectin [Homo sapiens] 32 0.29
gi|148833508 notch1 preproprotein [Homo sapiens] 32 0.38
>gi|4503413 heparin-binding EGF-like growth factor [Homo sapiens]
Length = 208
Score = 423 bits (1087), Expect = e-119
Identities = 208/208 (100%), Positives = 208/208 (100%)
Query: 1 MKLLPSVVLKLFLAAVLSALVTGESLERLRRGLAAGTSNPDPPTVSTDQLLPLGGGRDRK 60
MKLLPSVVLKLFLAAVLSALVTGESLERLRRGLAAGTSNPDPPTVSTDQLLPLGGGRDRK
Sbjct: 1 MKLLPSVVLKLFLAAVLSALVTGESLERLRRGLAAGTSNPDPPTVSTDQLLPLGGGRDRK 60
Query: 61 VRDLQEADLDLLRVTLSSKPQALATPNKEEHGKRKKKGKGLGKKRDPCLRKYKDFCIHGE 120
VRDLQEADLDLLRVTLSSKPQALATPNKEEHGKRKKKGKGLGKKRDPCLRKYKDFCIHGE
Sbjct: 61 VRDLQEADLDLLRVTLSSKPQALATPNKEEHGKRKKKGKGLGKKRDPCLRKYKDFCIHGE 120
Query: 121 CKYVKELRAPSCICHPGYHGERCHGLSLPVENRLYTYDHTTILAVVAVVLSSVCLLVIVG 180
CKYVKELRAPSCICHPGYHGERCHGLSLPVENRLYTYDHTTILAVVAVVLSSVCLLVIVG
Sbjct: 121 CKYVKELRAPSCICHPGYHGERCHGLSLPVENRLYTYDHTTILAVVAVVLSSVCLLVIVG 180
Query: 181 LLMFRYHRRGGYDVENEEKVKLGMTNSH 208
LLMFRYHRRGGYDVENEEKVKLGMTNSH
Sbjct: 181 LLMFRYHRRGGYDVENEEKVKLGMTNSH 208
>gi|4502199 amphiregulin preproprotein [Homo sapiens]
Length = 252
Score = 82.0 bits (201), Expect = 3e-16
Identities = 55/150 (36%), Positives = 78/150 (52%), Gaps = 13/150 (8%)
Query: 70 DLLRVTLSSKPQALATP--NKEEHGKRKKKGKGLGK------KRDPCLRKYKDFCIHGEC 121
D +RV KP T N + KRKKKG GK K++PC ++++FCIHGEC
Sbjct: 100 DSVRVEQVVKPPQNKTESENTSDKPKRKKKGGKNGKNRRNRKKKNPCNAEFQNFCIHGEC 159
Query: 122 KYVKELRAPSCICHPGYHGERCHGLSLPVENRLYTYDHTTILAVVAVVLSSVCL---LVI 178
KY++ L A +C C Y GERC S+ + + + LA +A +S+V L VI
Sbjct: 160 KYIEHLEAVTCKCQQEYFGERCGEKSMKTHSMIDSSLSKIALAAIAAFMSAVILTAVAVI 219
Query: 179 VGLLMFRYHRRGGYDVENEEKVKLGMTNSH 208
L +Y R+ Y+ E EE+ KL N +
Sbjct: 220 TVQLRRQYVRK--YEGEAEERKKLRQENGN 247
>gi|113415639 PREDICTED: amphiregulin B [Homo sapiens]
Length = 252
Score = 82.0 bits (201), Expect = 3e-16
Identities = 55/150 (36%), Positives = 78/150 (52%), Gaps = 13/150 (8%)
Query: 70 DLLRVTLSSKPQALATP--NKEEHGKRKKKGKGLGK------KRDPCLRKYKDFCIHGEC 121
D +RV KP T N + KRKKKG GK K++PC ++++FCIHGEC
Sbjct: 100 DSVRVEQVVKPPQNKTESENTSDKPKRKKKGGKNGKNRRNRKKKNPCNAEFQNFCIHGEC 159
Query: 122 KYVKELRAPSCICHPGYHGERCHGLSLPVENRLYTYDHTTILAVVAVVLSSVCL---LVI 178
KY++ L A +C C Y GERC S+ + + + LA +A +S+V L VI
Sbjct: 160 KYIEHLEAVTCKCQQEYFGERCGEKSMKTHSMIDSSLSKIALAAIAAFMSAVILTAVAVI 219
Query: 179 VGLLMFRYHRRGGYDVENEEKVKLGMTNSH 208
L +Y R+ Y+ E EE+ KL N +
Sbjct: 220 TVQLRRQYVRK--YEGEAEERKKLRQENGN 247
>gi|4502461 betacellulin [Homo sapiens]
Length = 178
Score = 52.8 bits (125), Expect = 2e-07
Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 4/74 (5%)
Query: 108 CLRKYKDFCIHGECKYVKELRAPSCICHPGYHGERCHGLSLPVENRLYTYDHTTILAVVA 167
C ++YK +CI G C++V + PSC+C GY G RC + L D IL +
Sbjct: 69 CPKQYKHYCIKGRCRFVVAEQTPSCVCDEGYIGARCERVDL----FYLRGDRGQILVICL 124
Query: 168 VVLSSVCLLVIVGL 181
+ + V +++++G+
Sbjct: 125 IAVMVVFIILVIGV 138
>gi|153791414 transforming growth factor, alpha isoform 2 [Homo
sapiens]
Length = 159
Score = 51.6 bits (122), Expect = 5e-07
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 108 CLRKYKDFCIHGECKYVKELRAPSCICHPGYHGERC-HGLSLPVENRLYTYDHTTILAVV 166
C + FC HG C+++ + P+C+CH GY G RC H L V T L VV
Sbjct: 46 CPDSHTQFCFHGTCRFLVQEDKPACVCHSGYVGARCEHADLLAVVAASQKKQAITALVVV 105
Query: 167 AVVLSSVCLLVIV 179
++V +V ++ V
Sbjct: 106 SIVALAVLIITCV 118
>gi|4507461 transforming growth factor, alpha isoform 1 [Homo
sapiens]
Length = 160
Score = 51.6 bits (122), Expect = 5e-07
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 108 CLRKYKDFCIHGECKYVKELRAPSCICHPGYHGERC-HGLSLPVENRLYTYDHTTILAVV 166
C + FC HG C+++ + P+C+CH GY G RC H L V T L VV
Sbjct: 47 CPDSHTQFCFHGTCRFLVQEDKPACVCHSGYVGARCEHADLLAVVAASQKKQAITALVVV 106
Query: 167 AVVLSSVCLLVIV 179
++V +V ++ V
Sbjct: 107 SIVALAVLIITCV 119
>gi|12383051 transmembrane protein with EGF-like and two
follistatin-like domains 2 [Homo sapiens]
Length = 374
Score = 50.1 bits (118), Expect = 1e-06
Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 10/79 (12%)
Query: 107 PCLRKYKDFCIHGECKYVKELRAPSCICHPGYHGERCHGLSLPVENRLYT------YDHT 160
PC Y FC+HG+C++ ++ PSC C GY G+ C V LY + +
Sbjct: 264 PCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSV---LYVVPGPVRFQYV 320
Query: 161 TILAVVAVV-LSSVCLLVI 178
I AV+ + ++ +C++V+
Sbjct: 321 LIAAVIGTIQIAVICVVVL 339
>gi|29568105 transmembrane protein with EGF-like and two
follistatin-like domains 1 [Homo sapiens]
Length = 380
Score = 48.5 bits (114), Expect = 4e-06
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 5/79 (6%)
Query: 107 PCLRKYKDFCIHGECKYVKELRAPSCICHPGYHGERCHGLSLPVENRLYTYDHTTIL--A 164
PC +CIHG+C+++ + SC C GY G+ C + LY L
Sbjct: 274 PCPENLNGYCIHGKCEFIYSTQKASCRCESGYTGQHCEKTDFSI---LYVVPSRQKLTHV 330
Query: 165 VVAVVLSSVCLLVIVGLLM 183
++A ++ +V + +IV ++M
Sbjct: 331 LIAAIIGAVQIAIIVAIVM 349
>gi|61806622 epithelial mitogen [Homo sapiens]
Length = 133
Score = 46.2 bits (108), Expect = 2e-05
Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 108 CLRKYKDFCIHGECKYVKELRAPSCICHPGYHGERCHGLSLPVENRLYTYDHTTILAVVA 167
CL + +CI+G C + EL C C GY GERC L+L + +Y+ + +
Sbjct: 51 CLEDHNSYCINGACAFHHELEKAICRCFTGYTGERCEHLTL-TSYAVDSYEKYIAIGIGV 109
Query: 168 VVLSSVCLLVIVGLLMFRYHR 188
+L S L++ + RY +
Sbjct: 110 GLLLSGFLVIFYCYIRKRYEK 130
>gi|236461846 neuregulin 1 isoform ndf43c [Homo sapiens]
Length = 308
Score = 43.5 bits (101), Expect = 1e-04
Identities = 26/81 (32%), Positives = 45/81 (55%), Gaps = 9/81 (11%)
Query: 108 CLRKYKDFCIHG-ECKYVKELRAPS---CICHPGYHGERC-HGLSLPVENRLYTYDHTTI 162
C K K FC++G EC VK+L PS C C PG+ G RC + + V+N+ + +
Sbjct: 28 CAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEKAEE---L 84
Query: 163 LAVVAVVLSSVCL-LVIVGLL 182
+ ++ +C+ L++VG++
Sbjct: 85 YQKRVLTITGICIALLVVGIM 105
>gi|7669526 neuregulin 1 isoform HRG-alpha [Homo sapiens]
Length = 640
Score = 43.5 bits (101), Expect = 1e-04
Identities = 26/81 (32%), Positives = 45/81 (55%), Gaps = 9/81 (11%)
Query: 108 CLRKYKDFCIHG-ECKYVKELRAPS---CICHPGYHGERC-HGLSLPVENRLYTYDHTTI 162
C K K FC++G EC VK+L PS C C PG+ G RC + + V+N+ + +
Sbjct: 182 CAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEKAEE---L 238
Query: 163 LAVVAVVLSSVCL-LVIVGLL 182
+ ++ +C+ L++VG++
Sbjct: 239 YQKRVLTITGICIALLVVGIM 259
>gi|7669520 neuregulin 1 isoform ndf43 [Homo sapiens]
Length = 462
Score = 43.5 bits (101), Expect = 1e-04
Identities = 26/81 (32%), Positives = 45/81 (55%), Gaps = 9/81 (11%)
Query: 108 CLRKYKDFCIHG-ECKYVKELRAPS---CICHPGYHGERC-HGLSLPVENRLYTYDHTTI 162
C K K FC++G EC VK+L PS C C PG+ G RC + + V+N+ + +
Sbjct: 182 CAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEKAEE---L 238
Query: 163 LAVVAVVLSSVCL-LVIVGLL 182
+ ++ +C+ L++VG++
Sbjct: 239 YQKRVLTITGICIALLVVGIM 259
>gi|4557567 epiregulin preproprotein [Homo sapiens]
Length = 169
Score = 41.6 bits (96), Expect = 5e-04
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 108 CLRKYKDFCIHGECKYVKELRAPSCICHPGYHGERCHGLSLPVENRLYTYDHTTILAVVA 167
C +C+HG+C Y+ ++ C C GY G RC L V L + +
Sbjct: 68 CSSDMNGYCLHGQCIYLVDMSQNYCRCEVGYTGVRCEHFFLTVHQPL-----SKEYVALT 122
Query: 168 VVLSSVCLLVIVG 180
V+L + L+ +VG
Sbjct: 123 VILIILFLITVVG 135
>gi|166362728 epidermal growth factor (beta-urogastrone) [Homo
sapiens]
Length = 1207
Score = 40.8 bits (94), Expect = 8e-04
Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 5/77 (6%)
Query: 108 CLRKYKDFCIH-GECKYVKELRAPSCICHPGYHGERCHGLSLPVENRLYTYDHTTILAVV 166
C + +C+H G C Y++ L +C C GY GERC L + + H
Sbjct: 976 CPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDL----KWWELRHAGHGQQQ 1031
Query: 167 AVVLSSVCLLVIVGLLM 183
V++ +VC++V+V LL+
Sbjct: 1032 KVIVVAVCVVVLVMLLL 1048
>gi|20070380 neuregulin 4 [Homo sapiens]
Length = 115
Score = 38.9 bits (89), Expect = 0.003
Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 4/69 (5%)
Query: 106 DPCLRKYKDFCIHGE-CKYVKELRAPSCICHPGYHGERCHGLSLP---VENRLYTYDHTT 161
+PC +K FC++G C + + +P C C Y G RC + LP ++ + ++
Sbjct: 7 EPCGPSHKSFCLNGGLCYVIPTIPSPFCRCVENYTGARCEEVFLPGSSIQTKSNLFEAFV 66
Query: 162 ILAVVAVVL 170
LAV+ ++
Sbjct: 67 ALAVLVTLI 75
>gi|7669528 neuregulin 2 isoform 2 [Homo sapiens]
Length = 844
Score = 37.0 bits (84), Expect = 0.012
Identities = 18/76 (23%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Query: 108 CLRKYKDFCIHGE-CKYVKELRAPSCICHPGYHGERCHGLSLPVENRLYTYDHTTILAVV 166
C K +C++G C Y++ + SC C GY G+RC ++ ++ +L +
Sbjct: 345 CNETAKSYCVNGGVCYYIEGINQLSCKCPVGYTGDRCQQFAMVNFSKAEELYQKRVLTIT 404
Query: 167 AVVLSSVCLLVIVGLL 182
+ ++ L++VG++
Sbjct: 405 GICVA----LLVVGIV 416
>gi|7669532 neuregulin 2 isoform 4 [Homo sapiens]
Length = 852
Score = 37.0 bits (84), Expect = 0.012
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 14/83 (16%)
Query: 108 CLRKYKDFCIHGE-CKYVKELRAPSCICHPGYHGERCH-----------GLSLPVENRLY 155
C K +C++G C Y++ + SC C GY G+RC G L LY
Sbjct: 345 CNETAKSYCVNGGVCYYIEGINQLSCKCPVGYTGDRCQQFAMVNFSKHLGFELKEAEELY 404
Query: 156 TYDHTTI--LAVVAVVLSSVCLL 176
TI + V +V+ VC++
Sbjct: 405 QKRVLTITGICVALLVVGIVCVV 427
>gi|11321571 slit homolog 3 [Homo sapiens]
Length = 1523
Score = 35.8 bits (81), Expect = 0.027
Identities = 12/28 (42%), Positives = 18/28 (64%), Gaps = 1/28 (3%)
Query: 116 CIHGECKYVKELRAPSCICHPGYHGERC 143
C HG+C ++ + P C+C PG+ GE C
Sbjct: 1417 CHHGQC-HISDQGEPYCLCQPGFSGEHC 1443
>gi|126012573 low density lipoprotein-related protein 2 [Homo sapiens]
Length = 4655
Score = 35.8 bits (81), Expect = 0.027
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 23/84 (27%)
Query: 116 CIHGECKYVKELRAPSCICHPGYHGERCH-----GLSLPVENRLYTYDHTTILAVVAVVL 170
C+HG Y E P C C GY G+ C G+S TT +AV+ +L
Sbjct: 4383 CMHGGNCYFDETDLPKCKCPSGYTGKYCEMAFSKGIS----------PGTTAVAVLLTIL 4432
Query: 171 SSVCLLVIVGLL----MFRYHRRG 190
L+V++G L F Y R G
Sbjct: 4433 ----LIVVIGALAIAGFFHYRRTG 4452
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 34.3 bits (77), Expect = 0.077
Identities = 13/29 (44%), Positives = 19/29 (65%), Gaps = 2/29 (6%)
Query: 116 CIHGECKYVKELRAPSCICHPGYHGERCH 144
CIHG C + + SC+C PG+ G+RC+
Sbjct: 654 CIHGIC--MDGINRYSCVCSPGFTGQRCN 680
Score = 31.2 bits (69), Expect = 0.65
Identities = 13/30 (43%), Positives = 19/30 (63%), Gaps = 2/30 (6%)
Query: 114 DFCIHGECKYVKELRAPSCICHPGYHGERC 143
D C HG+C+ + + +CIC+PGY G C
Sbjct: 577 DPCHHGQCQ--DGIDSYTCICNPGYMGAIC 604
Score = 28.9 bits (63), Expect = 3.2
Identities = 9/23 (39%), Positives = 14/23 (60%)
Query: 121 CKYVKELRAPSCICHPGYHGERC 143
CK + +C+C PG+ G+RC
Sbjct: 848 CKESPNFESYTCLCAPGWQGQRC 870
Score = 28.9 bits (63), Expect = 3.2
Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 5/41 (12%)
Query: 106 DPCLRKYKDFCIHG-ECKYVKELRAPSCICHPGYHGERCHG 145
D C R C++G +C + + SC C PG+ GERC G
Sbjct: 1227 DDCARG--PHCLNGGQC--MDRIGGYSCRCLPGFAGERCEG 1263
>gi|4758832 neuregulin 2 isoform 1 [Homo sapiens]
Length = 850
Score = 34.3 bits (77), Expect = 0.077
Identities = 23/81 (28%), Positives = 42/81 (51%), Gaps = 9/81 (11%)
Query: 108 CLRKYKDFCIHGE-CKYVKELRAPSCICHPGYHGERCHGLSLPVENRLYTYD----HTTI 162
C K +C++G C Y++ + SC C G+ G+RC LP+ RLY D +
Sbjct: 345 CNETAKSYCVNGGVCYYIEGINQLSCKCPNGFFGQRCLE-KLPL--RLYMPDPKQKAEEL 401
Query: 163 LAVVAVVLSSVCL-LVIVGLL 182
+ ++ +C+ L++VG++
Sbjct: 402 YQKRVLTITGICVALLVVGIV 422
>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
Length = 510
Score = 33.5 bits (75), Expect = 0.13
Identities = 17/47 (36%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
Query: 162 ILAVVAVVLSSVCLLVIVGLLMFRYHRRGGYDVENEEKVKLGMTNSH 208
++ V+A +L CLLV+V +LM RYHRR + + + +L +T +
Sbjct: 352 VVGVIAALL--FCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTREN 396
>gi|7669530 neuregulin 2 isoform 3 [Homo sapiens]
Length = 858
Score = 33.5 bits (75), Expect = 0.13
Identities = 13/37 (35%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Query: 108 CLRKYKDFCIHGE-CKYVKELRAPSCICHPGYHGERC 143
C K +C++G C Y++ + SC C G+ G+RC
Sbjct: 345 CNETAKSYCVNGGVCYYIEGINQLSCKCPNGFFGQRC 381
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 32.7 bits (73), Expect = 0.22
Identities = 15/30 (50%), Positives = 17/30 (56%), Gaps = 2/30 (6%)
Query: 114 DFCIHGECKYVKELRAPSCICHPGYHGERC 143
D C HG C V + + SC C PGY G RC
Sbjct: 552 DPCHHGRC--VDGIASFSCACAPGYTGTRC 579
Score = 28.5 bits (62), Expect = 4.2
Identities = 16/44 (36%), Positives = 20/44 (45%), Gaps = 2/44 (4%)
Query: 100 GLGKKRDPCLRKYKDFCIHGECKYVKELRAPSCICHPGYHGERC 143
G G PCL C +G R +C+C PG+ GERC
Sbjct: 35 GPGAAAPPCLDGSP--CANGGRCTQLPSREAACLCPPGWVGERC 76
Score = 28.5 bits (62), Expect = 4.2
Identities = 12/31 (38%), Positives = 15/31 (48%), Gaps = 3/31 (9%)
Query: 116 CIHGECKYVKELRAPS---CICHPGYHGERC 143
C H C + AP C+C PG+ G RC
Sbjct: 699 CAHEPCSHGICYDAPGGFRCVCEPGWSGPRC 729
Score = 28.5 bits (62), Expect = 4.2
Identities = 9/22 (40%), Positives = 14/22 (63%)
Query: 132 CICHPGYHGERCHGLSLPVENR 153
C+CH G+ G RC + P E++
Sbjct: 1232 CLCHAGFSGPRCQTVLSPCESQ 1253
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 32.7 bits (73), Expect = 0.22
Identities = 17/62 (27%), Positives = 26/62 (41%), Gaps = 5/62 (8%)
Query: 88 KEEHGKRKKKGKGLGKKRDPCLRKYKDFCIHGECKYVKELRAPSCICHPGYHGERCHGLS 147
K +H +R + G + R C+ C+HG C + C C PG+ G+ C
Sbjct: 81 KTDHRQRLQCCHGFYESRGFCVPLCAQECVHGRC-----VAPNQCQCVPGWRGDDCSSEC 135
Query: 148 LP 149
P
Sbjct: 136 AP 137
Score = 28.9 bits (63), Expect = 3.2
Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 4/40 (10%)
Query: 108 CLRKYKDFCI--HGECKYVKELRAPSC--ICHPGYHGERC 143
C K C+ +G C R PSC C PG +G+RC
Sbjct: 580 CTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRC 619
Score = 27.7 bits (60), Expect = 7.2
Identities = 15/52 (28%), Positives = 21/52 (40%), Gaps = 4/52 (7%)
Query: 96 KKGKGLGKKRDPCLRKYKDFCIHGECKYVKEL----RAPSCICHPGYHGERC 143
K+G G PC F + C+ E + +C C PG+HG C
Sbjct: 469 KEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHC 520
Score = 27.3 bits (59), Expect = 9.4
Identities = 11/27 (40%), Positives = 15/27 (55%), Gaps = 2/27 (7%)
Query: 119 GECKYVKELRAPSCI--CHPGYHGERC 143
G C L+ P+C+ C PGY+G C
Sbjct: 161 GVCSCPSGLQPPNCLQPCTPGYYGPAC 187
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 32.7 bits (73), Expect = 0.22
Identities = 11/28 (39%), Positives = 16/28 (57%), Gaps = 1/28 (3%)
Query: 116 CIHGECKYVKELRAPSCICHPGYHGERC 143
C+HG C+ + C+C PG+ GE C
Sbjct: 1427 CLHGHCQ-ASGTKGAHCVCDPGFSGELC 1453
Score = 29.3 bits (64), Expect = 2.5
Identities = 12/29 (41%), Positives = 17/29 (58%), Gaps = 1/29 (3%)
Query: 116 CIHGECKYVKELRAPSCICHPGYHGERCH 144
C+HG+C + L + SC C GY G C+
Sbjct: 1386 CVHGQCVPLDAL-SYSCQCQDGYSGALCN 1413
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 32.7 bits (73), Expect = 0.22
Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 10/67 (14%)
Query: 131 SCICHPGYHGERCHGLSLPVEN-RLYT-------YDHTTILAVVAVVLSSVCLLVIVGLL 182
+C C PG+ G RC +L +E YT + ++ AV ++L ++V++GL
Sbjct: 810 TCYCSPGFKGIRCDQAALMMEELNPYTKISPALGAERHSVGAVTGIMLLLFLIVVLLGL- 868
Query: 183 MFRYHRR 189
F +HRR
Sbjct: 869 -FAWHRR 874
Score = 29.6 bits (65), Expect = 1.9
Identities = 14/51 (27%), Positives = 23/51 (45%), Gaps = 5/51 (9%)
Query: 93 KRKKKGKGLGKKRDPCLRKYKDFCIHGECKYVKELRAPSCICHPGYHGERC 143
+R + G + D C+ + C+HG C + +C C PG+ G C
Sbjct: 84 RRSQCCPGYYESGDFCIPLCTEECVHGRC-----VSPDTCHCEPGWGGPDC 129
Score = 27.7 bits (60), Expect = 7.2
Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 5/35 (14%)
Query: 116 CIHG-ECKYVKELRAPSCICHPGYHGERCHGLSLP 149
C HG C + RA C+C PGY G C L P
Sbjct: 191 CRHGASC----DPRAGECLCAPGYTGVYCEELCPP 221
Score = 27.3 bits (59), Expect = 9.4
Identities = 11/27 (40%), Positives = 14/27 (51%), Gaps = 2/27 (7%)
Query: 119 GECKYVKELRAPSC--ICHPGYHGERC 143
G C+ R P C IC PG++G C
Sbjct: 592 GSCECAPGFRGPLCQRICPPGFYGHGC 618
>gi|116235485 delta-notch-like EGF repeat-containing transmembrane
[Homo sapiens]
Length = 737
Score = 32.7 bits (73), Expect = 0.22
Identities = 13/28 (46%), Positives = 16/28 (57%), Gaps = 2/28 (7%)
Query: 116 CIHGECKYVKELRAPSCICHPGYHGERC 143
C HG C+ V + C+C PGYHG C
Sbjct: 477 CAHGTCRSVGT--SYKCLCDPGYHGLYC 502
Score = 28.5 bits (62), Expect = 4.2
Identities = 14/40 (35%), Positives = 17/40 (42%), Gaps = 5/40 (12%)
Query: 106 DPCLRKYKDFCIHGECKYVKELRAPS--CICHPGYHGERC 143
DPC + C HG C + CIC+ GY G C
Sbjct: 96 DPCA---SNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNC 132
>gi|75709198 nephronectin [Homo sapiens]
Length = 565
Score = 32.3 bits (72), Expect = 0.29
Identities = 13/29 (44%), Positives = 16/29 (55%), Gaps = 5/29 (17%)
Query: 116 CIHGECKYVKELRAPSCICHPGYHGERCH 144
C HGEC + C CHPGY G+ C+
Sbjct: 64 CKHGEC-----IGPNKCKCHPGYAGKTCN 87
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 32.0 bits (71), Expect = 0.38
Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 3/40 (7%)
Query: 106 DPCLRKYKDFCIHGECKYVKELRAPSCICHPGYHGERCHG 145
DP R K F +G C V ++ SC C PG+ GERC G
Sbjct: 1230 DPVSRSPKCFN-NGTC--VDQVGGYSCTCPPGFVGERCEG 1266
Score = 29.6 bits (65), Expect = 1.9
Identities = 11/28 (39%), Positives = 14/28 (50%), Gaps = 2/28 (7%)
Query: 116 CIHGECKYVKELRAPSCICHPGYHGERC 143
C+HG C+ L C C PG+ G C
Sbjct: 725 CVHGACR--DSLNGYKCDCDPGWSGTNC 750
Score = 29.3 bits (64), Expect = 2.5
Identities = 12/30 (40%), Positives = 16/30 (53%), Gaps = 2/30 (6%)
Query: 114 DFCIHGECKYVKELRAPSCICHPGYHGERC 143
D C +G CK + +C+C PGY G C
Sbjct: 573 DPCHYGSCK--DGVATFTCLCRPGYTGHHC 600
Score = 29.3 bits (64), Expect = 2.5
Identities = 9/25 (36%), Positives = 16/25 (64%)
Query: 119 GECKYVKELRAPSCICHPGYHGERC 143
GEC+ ++ + SC+C G+ G+ C
Sbjct: 842 GECRQSEDYESFSCVCPTGWQGQTC 866
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.139 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,724,119
Number of Sequences: 37866
Number of extensions: 422650
Number of successful extensions: 1913
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 71
Number of HSP's that attempted gapping in prelim test: 1580
Number of HSP's gapped (non-prelim): 413
length of query: 208
length of database: 18,247,518
effective HSP length: 98
effective length of query: 110
effective length of database: 14,536,650
effective search space: 1599031500
effective search space used: 1599031500
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.