Guide to the Human Genome
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Name: TGFA Sequence: fasta or formatted (160aa) NCBI GI: 4507461
Description:

transforming growth factor, alpha isoform 1

Referenced in:

Epidermal Growth Factor

Other entries for this name:
alt prot [159aa] transforming growth factor, alpha isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            14.4         23           3
 C cysteine            9.4         15           2
 D aspartate           3.1          5           1
 E glutamate           3.8          6           1
 F phenylalanine       3.1          5           1
 G glycine             3.8          6           1
 H histidine           5.6          9           1
 I isoleucine          4.4          7           2
 K lysine              3.8          6           2
 L leucine            10.0         16           2
 M methionine          0.6          1           1
 N asparagine          1.2          2           1
 P proline             4.4          7           2
 Q glutamine           4.4          7           1
 R arginine            3.8          6           1
 S serine              6.9         11           1
 T threonine           4.4          7           1
 V valine             11.9         19           3
 W tryptophan          0.6          1           1
 Y tyrosine            0.6          1           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   transforming growth factor, alpha isoform 1 
TGFA                  0.980   transforming growth factor, alpha isoform 2 
BTC                   0.173   betacellulin 
TMEFF1                0.117   transmembrane protein with EGF-like and two follista...
TMEFF2                0.111   transmembrane protein with EGF-like and two follista...
EGF                   0.094   epidermal growth factor (beta-urogastrone) 
EPGN                  0.091   epithelial mitogen 
HBEGF                 0.088   heparin-binding EGF-like growth factor 
EREG                  0.085   epiregulin preproprotein 
AREG                  0.062   amphiregulin preproprotein 
AREGB                 0.062   PREDICTED: amphiregulin B 
NRG2                  0.059   neuregulin 2 isoform 2 
NRG4                  0.052   neuregulin 4 
NRG1                  0.052   neuregulin 1 isoform ndf43b 
NRG1                  0.052   neuregulin 1 isoform HRG-beta2b 
NRG1                  0.052   neuregulin 1 isoform HRG-beta2 
NRG1                  0.049   neuregulin 1 isoform HRG-alpha 
NRG1                  0.049   neuregulin 1 isoform ndf43 
NRG1                  0.049   neuregulin 1 isoform ndf43c 
LRP2                  0.039   low density lipoprotein-related protein 2 
NRG2                  0.039   neuregulin 2 isoform 1 
NRG2                  0.039   neuregulin 2 isoform 4 
LRP1B                 0.033   low density lipoprotein-related protein 1B precursor...
NRG1                  0.033   neuregulin 1 isoform HRG-beta1b 
NRG1                  0.033   neuregulin 1 isoform HRG-beta1 
NRG1                  0.029   neuregulin 1 isoform HRG-beta1d 
NRG1                  0.029   neuregulin 1 isoform HRG-beta1c 
HSPG2                 0.029   heparan sulfate proteoglycan 2 
NRG3                  0.029   neuregulin 3 
NOTCH3                0.029   Notch homolog 3 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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