BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4503059 crystallin, beta A4 [Homo sapiens] (196 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4503059 crystallin, beta A4 [Homo sapiens] 426 e-120 gi|12056461 crystallin, beta A3 [Homo sapiens] 300 7e-82 gi|16936542 crystallin, beta A2 [Homo sapiens] 221 3e-58 gi|16936540 crystallin, beta A2 [Homo sapiens] 221 3e-58 gi|7019357 crystallin, beta A2 [Homo sapiens] 221 3e-58 gi|4503061 crystallin, beta B1 [Homo sapiens] 165 2e-41 gi|4503063 crystallin, beta B2 [Homo sapiens] 150 7e-37 gi|4758074 crystallin, beta B3 [Homo sapiens] 146 1e-35 gi|148491074 crystallin, gamma B [Homo sapiens] 110 1e-24 gi|10518338 crystallin, gamma C [Homo sapiens] 110 1e-24 gi|89886227 absent in melanoma 1-like [Homo sapiens] 107 8e-24 gi|148491057 crystallin, gamma A [Homo sapiens] 102 3e-22 gi|8922120 crystallin, gamma S [Homo sapiens] 99 2e-21 gi|62988361 absent in melanoma 1 [Homo sapiens] 97 9e-21 gi|13377002 crystallin, gamma D [Homo sapiens] 95 3e-20 gi|90403579 beta-gamma crystallin domain containing 3 [Homo sapi... 89 3e-18 gi|21389517 gammaN-crystallin [Homo sapiens] 85 3e-17 gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens] 28 5.0 gi|4826764 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1... 27 8.5 gi|94721268 villin-like protein [Homo sapiens] 27 8.5 >gi|4503059 crystallin, beta A4 [Homo sapiens] Length = 196 Score = 426 bits (1096), Expect = e-120 Identities = 196/196 (100%), Positives = 196/196 (100%) Query: 1 MTLQCTKSAGPWKMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHA 60 MTLQCTKSAGPWKMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHA Sbjct: 1 MTLQCTKSAGPWKMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHA 60 Query: 61 GFQGQQYILERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKG 120 GFQGQQYILERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKG Sbjct: 61 GFQGQQYILERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKG 120 Query: 121 ELSDDYPSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWG 180 ELSDDYPSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWG Sbjct: 121 ELSDDYPSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWG 180 Query: 181 SHAPTFQVQSIRRIQQ 196 SHAPTFQVQSIRRIQQ Sbjct: 181 SHAPTFQVQSIRRIQQ 196 >gi|12056461 crystallin, beta A3 [Homo sapiens] Length = 215 Score = 300 bits (767), Expect = 7e-82 Identities = 129/189 (68%), Positives = 157/189 (83%) Query: 8 SAGPWKMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQY 67 S GPWK+ ++D++ FQG+R EFT+ CP+V E F+ VRSLKV SGAW+G+EH F GQQ+ Sbjct: 27 SLGPWKITIYDQENFQGKRMEFTSSCPNVSERSFDNVRSLKVESGAWIGYEHTSFCGQQF 86 Query: 68 ILERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGELSDDYP 127 ILERGEYP WDAW G+ AY ERL SFRP ANH++S++TIFE+ENF+G++ E+SDDYP Sbjct: 87 ILERGEYPRWDAWSGSNAYHIERLMSFRPICSANHKESKMTIFEKENFIGRQWEISDDYP 146 Query: 128 SLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQ 187 SLQAMGW NEVGS + SGAWVC Q+PGYRG+QY+LECDHH GDYKH+REWGSHA T Q Sbjct: 147 SLQAMGWFNNEVGSMKIQSGAWVCYQYPGYRGYQYILECDHHGGDYKHWREWGSHAQTSQ 206 Query: 188 VQSIRRIQQ 196 +QSIRRIQQ Sbjct: 207 IQSIRRIQQ 215 Score = 62.4 bits (150), Expect = 2e-10 Identities = 30/85 (35%), Positives = 52/85 (61%), Gaps = 6/85 (7%) Query: 5 CTKSAGPWKMVVWDEDGFQGRRHEFTAECPSVLELGF--ETVRSLKVLSGAWVGFEHAGF 62 C+ + KM +++++ F GR+ E + + PS+ +G+ V S+K+ SGAWV +++ G+ Sbjct: 117 CSANHKESKMTIFEKENFIGRQWEISDDYPSLQAMGWFNNEVGSMKIQSGAWVCYQYPGY 176 Query: 63 QGQQYILE----RGEYPSWDAWGGN 83 +G QYILE G+Y W WG + Sbjct: 177 RGYQYILECDHHGGDYKHWREWGSH 201 >gi|16936542 crystallin, beta A2 [Homo sapiens] Length = 197 Score = 221 bits (563), Expect = 3e-58 Identities = 102/186 (54%), Positives = 134/186 (72%), Gaps = 1/186 (0%) Query: 11 PWKMVVWDEDGFQGRRHEFTAECPSVLELG-FETVRSLKVLSGAWVGFEHAGFQGQQYIL 69 P + +WDE+ FQGRR ++C +V E G VRS+KV +G WV FE+ FQGQQ+IL Sbjct: 11 PASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFIL 70 Query: 70 ERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGELSDDYPSL 129 E+G+YP W AW G++++ + +L SFRP CANH DSR+T+FE +NF G K +L DDYPSL Sbjct: 71 EKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSL 130 Query: 130 QAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQVQ 189 +MGW +VGS V SGAWV Q+PGYRG+QYVLE D HSG++ + E G+ A T Q+Q Sbjct: 131 PSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQAHTGQLQ 190 Query: 190 SIRRIQ 195 SIRR+Q Sbjct: 191 SIRRVQ 196 >gi|16936540 crystallin, beta A2 [Homo sapiens] Length = 197 Score = 221 bits (563), Expect = 3e-58 Identities = 102/186 (54%), Positives = 134/186 (72%), Gaps = 1/186 (0%) Query: 11 PWKMVVWDEDGFQGRRHEFTAECPSVLELG-FETVRSLKVLSGAWVGFEHAGFQGQQYIL 69 P + +WDE+ FQGRR ++C +V E G VRS+KV +G WV FE+ FQGQQ+IL Sbjct: 11 PASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFIL 70 Query: 70 ERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGELSDDYPSL 129 E+G+YP W AW G++++ + +L SFRP CANH DSR+T+FE +NF G K +L DDYPSL Sbjct: 71 EKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSL 130 Query: 130 QAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQVQ 189 +MGW +VGS V SGAWV Q+PGYRG+QYVLE D HSG++ + E G+ A T Q+Q Sbjct: 131 PSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQAHTGQLQ 190 Query: 190 SIRRIQ 195 SIRR+Q Sbjct: 191 SIRRVQ 196 >gi|7019357 crystallin, beta A2 [Homo sapiens] Length = 197 Score = 221 bits (563), Expect = 3e-58 Identities = 102/186 (54%), Positives = 134/186 (72%), Gaps = 1/186 (0%) Query: 11 PWKMVVWDEDGFQGRRHEFTAECPSVLELG-FETVRSLKVLSGAWVGFEHAGFQGQQYIL 69 P + +WDE+ FQGRR ++C +V E G VRS+KV +G WV FE+ FQGQQ+IL Sbjct: 11 PASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFIL 70 Query: 70 ERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGELSDDYPSL 129 E+G+YP W AW G++++ + +L SFRP CANH DSR+T+FE +NF G K +L DDYPSL Sbjct: 71 EKGDYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSL 130 Query: 130 QAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQVQ 189 +MGW +VGS V SGAWV Q+PGYRG+QYVLE D HSG++ + E G+ A T Q+Q Sbjct: 131 PSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELGTQAHTGQLQ 190 Query: 190 SIRRIQ 195 SIRR+Q Sbjct: 191 SIRRVQ 196 >gi|4503061 crystallin, beta B1 [Homo sapiens] Length = 252 Score = 165 bits (418), Expect = 2e-41 Identities = 83/187 (44%), Positives = 128/187 (68%), Gaps = 11/187 (5%) Query: 10 GPWKMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQYIL 69 G +++VV++ + FQGRR EF+ EC ++ + GF+ VRS+ V +G WV FE + F+G+ +IL Sbjct: 57 GNYRLVVFELENFQGRRAEFSGECSNLADRGFDRVRSIIVSAGPWVAFEQSNFRGEMFIL 116 Query: 70 ERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGEL-SDDYPS 128 E+GEYP W+ W +++Y ++RL SFRP + ++ ++++FE NF G E+ DD PS Sbjct: 117 EKGEYPRWNTW--SSSYRSDRLMSFRPIK-MDAQEHKISLFEGANFKGNTIEIQGDDAPS 173 Query: 129 LQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQV 188 L G+ + VGS V SG WV Q+PGYRG+QY+LE GD++H+ EWG+ P Q+ Sbjct: 174 LWVYGF-SDRVGSVKVSSGTWVGYQYPGYRGYQYLLE----PGDFRHWNEWGAFQP--QM 226 Query: 189 QSIRRIQ 195 QS+RR++ Sbjct: 227 QSLRRLR 233 >gi|4503063 crystallin, beta B2 [Homo sapiens] Length = 205 Score = 150 bits (379), Expect = 7e-37 Identities = 77/184 (41%), Positives = 116/184 (63%), Gaps = 11/184 (5%) Query: 13 KMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQYILERG 72 K+++++++ FQG HE CP++ E G E S+ V +G WVG+E A +G+Q++ E+G Sbjct: 18 KIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKG 77 Query: 73 EYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGE-LSDDYPSLQA 131 EYP WD+W ++ + L+S RP + ++ ++ ++E NF GKK E + DD PS A Sbjct: 78 EYPRWDSW--TSSRRTDSLSSLRPIK-VDSQEHKIILYENPNFTGKKMEIIDDDVPSFHA 134 Query: 132 MGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQVQSI 191 G++ +V S V SG WV Q+PGYRG QY+LE GDYK ++G AP QVQS+ Sbjct: 135 HGYQ-EKVSSVRVQSGTWVGYQYPGYRGLQYLLE----KGDYKDSSDFG--APHPQVQSV 187 Query: 192 RRIQ 195 RRI+ Sbjct: 188 RRIR 191 >gi|4758074 crystallin, beta B3 [Homo sapiens] Length = 211 Score = 146 bits (369), Expect = 1e-35 Identities = 78/187 (41%), Positives = 119/187 (63%), Gaps = 11/187 (5%) Query: 10 GPWKMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQYIL 69 G +K+++++ + FQG+R E +AECPS+ + E V S++V SG W+ FE F+G+Q++L Sbjct: 22 GSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVL 81 Query: 70 ERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGEL-SDDYPS 128 E+G+YP WDAW + + ++ L S RP + +L +FE F G+K E+ DD PS Sbjct: 82 EKGDYPRWDAW--SNSRDSDSLLSLRPLN-IDSPHHKLHLFENPAFSGRKMEIVDDDVPS 138 Query: 129 LQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQV 188 L A G++ + V S +G WV +FPGYRG QYV E G+Y+H+ EW + P Q+ Sbjct: 139 LWAHGFQ-DRVASVRAINGTWVGYEFPGYRGRQYVFE----RGEYRHWNEWDASQP--QL 191 Query: 189 QSIRRIQ 195 QS+RRI+ Sbjct: 192 QSVRRIR 198 >gi|148491074 crystallin, gamma B [Homo sapiens] Length = 175 Score = 110 bits (274), Expect = 1e-24 Identities = 64/185 (34%), Positives = 101/185 (54%), Gaps = 19/185 (10%) Query: 13 KMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQYILERG 72 K+ +++ FQGR +E T +CP+ L+ F S++V SG W+ +E +QG QY L RG Sbjct: 3 KITFYEDRAFQGRSYECTTDCPN-LQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRRG 61 Query: 73 EYPSWDAWGGNTAYPAERLTSFRPAACANHRDS---RLTIFEQENFLGKKGELSDDYPSL 129 EYP + W G L+ + C S R+ I++++ G+ EL+DD S+ Sbjct: 62 EYPDYQQWMG--------LSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCISV 113 Query: 130 QAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQVQ 189 Q + E+ S +V G+W+ + P YRG QY+L G+Y+ F +WG AP +V Sbjct: 114 QDR-FHLTEIHSLNVLEGSWILYEMPNYRGRQYLL----RPGEYRRFLDWG--APNAKVG 166 Query: 190 SIRRI 194 S+RR+ Sbjct: 167 SLRRV 171 >gi|10518338 crystallin, gamma C [Homo sapiens] Length = 174 Score = 110 bits (274), Expect = 1e-24 Identities = 65/182 (35%), Positives = 102/182 (56%), Gaps = 14/182 (7%) Query: 13 KMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQYILERG 72 K+ +++ FQGR +E T +CP+ L+ F S++V SG W+ +E +QGQQY+L RG Sbjct: 3 KITFYEDRAFQGRSYETTTDCPN-LQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRRG 61 Query: 73 EYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGELSDDYPSLQAM 132 EYP + W G + + R P ++ RL ++E+E+ G ELS+D PS+Q Sbjct: 62 EYPDYQQWMGLS--DSIRSCCLIPQTVSH----RLRLYEREDHKGLMMELSEDCPSIQDR 115 Query: 133 GWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQVQSIR 192 + +E+ S HV G WV + P YRG QY+L +Y+ ++WG A + S+R Sbjct: 116 -FHLSEIRSLHVLEGCWVLYELPNYRGRQYLL----RPQEYRRCQDWG--AMDAKAGSLR 168 Query: 193 RI 194 R+ Sbjct: 169 RV 170 >gi|89886227 absent in melanoma 1-like [Homo sapiens] Length = 616 Score = 107 bits (266), Expect = 8e-24 Identities = 69/189 (36%), Positives = 97/189 (51%), Gaps = 18/189 (9%) Query: 1 MTLQC--TKSAGPWKMVVWDEDGFQGRRHEFTAECPSVLELG------FETVRSLKVLSG 52 M L C + G + VV++ GFQGR E + + ++ + +V SL+VL G Sbjct: 110 MRLGCPSVEKPGEPRAVVYEAPGFQGRSWEVSRDIYNLQQPEDSQSPHLASVGSLRVLGG 169 Query: 53 AWVGFEHAGFQGQQYILERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQ 112 WVG+E GF+G QY+LE GEYP W WGG E LTS R + D + +FE Sbjct: 170 CWVGYEKEGFRGHQYLLEEGEYPDWSHWGGYD----ELLTSLR-VIRTDFGDPAVVLFEA 224 Query: 113 ENFLGKKGELSDDYPSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGD 172 +F G E+S P ++ + G + HV SG WV Q G+ G QYVLE G Sbjct: 225 MDFEGHGVEVSKALPDVELV-QHGPSTQAIHVLSGVWVAYQEVGFSGEQYVLE----KGV 279 Query: 173 YKHFREWGS 181 Y++ +WG+ Sbjct: 280 YRNCEDWGA 288 Score = 73.9 bits (180), Expect = 8e-14 Identities = 45/156 (28%), Positives = 75/156 (48%), Gaps = 13/156 (8%) Query: 14 MVVWDEDGFQGRRHEFTAECPSV-LELGFETVRSLKVLSGAWVGFEHAGFQGQQYILERG 72 +V+++ F+G E + P V L + +++ VLSG WV ++ GF G+QY+LE+G Sbjct: 219 VVLFEAMDFEGHGVEVSKALPDVELVQHGPSTQAIHVLSGVWVAYQEVGFSGEQYVLEKG 278 Query: 73 EYPSWDAWGGNTAYPAERLTSFRPAACANHRD----SRLTIFEQENFLGKKGELSDDYPS 128 Y + + WG + L S +P D S++ +F + +FLG DD + Sbjct: 279 VYRNCEDWGAGNS----TLASLQPVLQVGEHDLHFVSKIQLFSRPDFLGDHFSFEDDQAA 334 Query: 129 LQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVL 164 L A S VH G+W+ + G Q++L Sbjct: 335 LPA----SFRPQSCRVHGGSWILFDETNFEGDQHIL 366 Score = 73.2 bits (178), Expect = 1e-13 Identities = 59/195 (30%), Positives = 89/195 (45%), Gaps = 32/195 (16%) Query: 10 GPWKMVVWD----------EDGFQGRRHEFTAECPSVLELGFET---VRSLKVLSGAWVG 56 G + VVWD E+G +G + + T + G E V S V +G W+ Sbjct: 16 GSLRRVVWDYSTPEISLFSEEGLKGEQVKLTEALKN--SQGLEKPLQVASATVSAGLWLL 73 Query: 57 FEHAGFQGQQYILERGEYPSWDAWGGNTAYPAERLTSFRP-----AACANHRDSRLTIFE 111 + F+ YILE GEYP+ +AWG T+ P+ + S +P + + R ++E Sbjct: 74 YPKPLFEDTPYILEPGEYPTSEAWG--TSDPS--VGSLKPMRLGCPSVEKPGEPRAVVYE 129 Query: 112 QENFLGKKGELSDDYPSLQ----AMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECD 167 F G+ E+S D +LQ + VGS V G WV + G+RG QY+LE Sbjct: 130 APGFQGRSWEVSRDIYNLQQPEDSQSPHLASVGSLRVLGGCWVGYEKEGFRGHQYLLE-- 187 Query: 168 HHSGDYKHFREWGSH 182 G+Y + WG + Sbjct: 188 --EGEYPDWSHWGGY 200 Score = 62.4 bits (150), Expect = 2e-10 Identities = 44/153 (28%), Positives = 75/153 (49%), Gaps = 14/153 (9%) Query: 45 RSLKVLSGAWVGFEHAGFQGQQYILERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRD 104 +S +V G+W+ F+ F+G Q+IL GE+P+ A G A + + + Sbjct: 342 QSCRVHGGSWILFDETNFEGDQHILSEGEFPTLTAMG----CLASTVLGSLQKVSLHFSE 397 Query: 105 SRLTIFEQENFLGKKGELSDDYPSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVL 164 + ++ E F GK+ ELS + SLQA G+ N V S + G WV + +RG Q+++ Sbjct: 398 PSIFLYGLECFEGKEIELSREVRSLQAEGF-NNHVLSVRIKGGIWVLCEHSDFRGRQWLV 456 Query: 165 -ECDHHSGDYKHFREWGSHAPTFQVQSIRRIQQ 196 C+ W +++ T +V S+ I+Q Sbjct: 457 GSCE--------ITNWLTYSGTQRVGSLYPIKQ 481 Score = 40.4 bits (93), Expect = 0.001 Identities = 20/62 (32%), Positives = 35/62 (56%), Gaps = 1/62 (1%) Query: 22 FQGRRHEFTAECPSVLELGFET-VRSLKVLSGAWVGFEHAGFQGQQYILERGEYPSWDAW 80 F+G+ E + E S+ GF V S+++ G WV EH+ F+G+Q+++ E +W + Sbjct: 408 FEGKEIELSREVRSLQAEGFNNHVLSVRIKGGIWVLCEHSDFRGRQWLVGSCEITNWLTY 467 Query: 81 GG 82 G Sbjct: 468 SG 469 >gi|148491057 crystallin, gamma A [Homo sapiens] Length = 174 Score = 102 bits (253), Expect = 3e-22 Identities = 59/183 (32%), Positives = 97/183 (53%), Gaps = 16/183 (8%) Query: 13 KMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQYILERG 72 K+ +++ FQGR + ++CP+ L + F S++V SG W+ +E +QG QY L RG Sbjct: 3 KITFYEDRDFQGRCYNCISDCPN-LRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRG 61 Query: 73 EYPSWDAWGGNTAYPAERLTSFRPAACANHRDS-RLTIFEQENFLGKKGELSDDYPSLQA 131 +YP + W G + S + H S +L ++E++++ G EL+DD + Sbjct: 62 KYPDYQHWMGLS-------DSVQSCRIIPHTSSHKLRLYERDDYRGLMSELTDDCACVPE 114 Query: 132 MGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQVQSI 191 + + E+ S HV G WV + P YRG QY+L GDY+ + +WG +V S+ Sbjct: 115 L-FRLPEIYSLHVLEGCWVLYEMPNYRGRQYLL----RPGDYRRYHDWG--GADAKVGSL 167 Query: 192 RRI 194 RR+ Sbjct: 168 RRV 170 >gi|8922120 crystallin, gamma S [Homo sapiens] Length = 178 Score = 99.4 bits (246), Expect = 2e-21 Identities = 59/182 (32%), Positives = 92/182 (50%), Gaps = 12/182 (6%) Query: 13 KMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQYILERG 72 K+ +++ FQGRR++ +C S+KV G W +E F G YIL +G Sbjct: 7 KITFYEDKNFQGRRYDCDCDCAD-FHTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQG 65 Query: 73 EYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGELSDDYPSLQAM 132 EYP + W G +RL+S R + ++ IFE+ +F G+ E ++D PS+ Sbjct: 66 EYPEYQRWMGLN----DRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQ 121 Query: 133 GWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQVQSIR 192 + E+ S V G W+ + P YRG QY+L+ +Y+ +WG+ +P VQS R Sbjct: 122 -FHMREIHSCKVLEGVWIFYELPNYRGRQYLLD----KKEYRKPIDWGAASPA--VQSFR 174 Query: 193 RI 194 RI Sbjct: 175 RI 176 Score = 62.0 bits (149), Expect = 3e-10 Identities = 32/89 (35%), Positives = 53/89 (59%), Gaps = 5/89 (5%) Query: 8 SAGPWKMVVWDEDGFQGRRHEFTAECPSVLE-LGFETVRSLKVLSGAWVGFEHAGFQGQQ 66 S G +K+ ++++ F G+ +E T +CPS++E + S KVL G W+ +E ++G+Q Sbjct: 90 SGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQ 149 Query: 67 YILERGEYPSWDAWGGNTAYPAERLTSFR 95 Y+L++ EY WG A PA + SFR Sbjct: 150 YLLDKKEYRKPIDWG--AASPA--VQSFR 174 >gi|62988361 absent in melanoma 1 [Homo sapiens] Length = 1723 Score = 97.1 bits (240), Expect = 9e-21 Identities = 67/184 (36%), Positives = 96/184 (52%), Gaps = 27/184 (14%) Query: 13 KMVVWDEDGFQGRRHEF-TAECPSVLELG------------FETVRSLKVLSGAWVGFEH 59 K+VV+++ F+G+ E T C V+E G F +V S+KVL G WV +E Sbjct: 1219 KVVVYEKPFFEGKCVELETGMCSFVMEGGETEEATGDDHLPFTSVGSMKVLRGIWVAYEK 1278 Query: 60 AGFQGQQYILERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKK 119 GF G QY+LE GEY W AWGG Y E L S RP + ++ + ++ ++NF G K Sbjct: 1279 PGFTGHQYLLEEGEYRDWKAWGG---YNGE-LQSLRP-ILGDFSNAHMIMYSEKNF-GSK 1332 Query: 120 GELSD---DYPSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHF 176 G D +L+ G+ G + S +V SG WV + P + G QY+L+ G Y F Sbjct: 1333 GSSIDVLGIVANLKETGY-GVKTQSINVLSGVWVAYENPDFTGEQYILD----KGFYTSF 1387 Query: 177 REWG 180 +WG Sbjct: 1388 EDWG 1391 Score = 82.8 bits (203), Expect = 2e-16 Identities = 56/165 (33%), Positives = 78/165 (47%), Gaps = 26/165 (15%) Query: 46 SLKVLSGAWVGFEHAGFQGQQYILERGEYPSWDAWGGNTAYPAERLTSFRPAACANHR-- 103 S+KV G W+ +E GFQG +ILE GEYP W AY + S RP + Sbjct: 1158 SMKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEAAY----IGSMRPLKMGGRKVE 1213 Query: 104 ---DSRLTIFEQENFLGKKGELSDDYPSLQAMGWEGNE-----------VGSFHVHSGAW 149 D ++ ++E+ F GK EL S G E E VGS V G W Sbjct: 1214 FPTDPKVVVYEKPFFEGKCVELETGMCSFVMEGGETEEATGDDHLPFTSVGSMKVLRGIW 1273 Query: 150 VCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQVQSIRRI 194 V + PG+ G QY+LE G+Y+ ++ WG + ++QS+R I Sbjct: 1274 VAYEKPGFTGHQYLLE----EGEYRDWKAWGGY--NGELQSLRPI 1312 Score = 76.3 bits (186), Expect = 2e-14 Identities = 49/149 (32%), Positives = 77/149 (51%), Gaps = 7/149 (4%) Query: 16 VWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQYILERGEYP 75 ++ E FQG F E S ++ F T +S +V G+WV ++ F G QY+LE G YP Sbjct: 1419 LFSEPQFQGHSQSFE-ETTSQIDDSFST-KSCRVSGGSWVVYDGENFTGNQYVLEEGHYP 1476 Query: 76 SWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGELSDDYPSLQAMGWE 135 A G P S R + + +FE+E+F GKK EL+ + +L+++G+ Sbjct: 1477 CLSAMG---CPPGATFKSLR-FIDVEFSEPTIILFEREDFKGKKIELNAETVNLRSLGF- 1531 Query: 136 GNEVGSFHVHSGAWVCSQFPGYRGFQYVL 164 ++ S V G WV ++ YRG Q++L Sbjct: 1532 NTQIRSVQVIGGIWVTYEYGSYRGRQFLL 1560 Score = 68.6 bits (166), Expect = 3e-12 Identities = 44/163 (26%), Positives = 77/163 (47%), Gaps = 15/163 (9%) Query: 14 MVVWDEDGF--QGRRHEFTAECPSVLELGFET-VRSLKVLSGAWVGFEHAGFQGQQYILE 70 M+++ E F +G + ++ E G+ +S+ VLSG WV +E+ F G+QYIL+ Sbjct: 1321 MIMYSEKNFGSKGSSIDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYILD 1380 Query: 71 RGEYPSWDAWGGNTAYPAERLTSFRPAACAN----HRDSRLTIFEQENFLGKKGELSDDY 126 +G Y S++ WGG +++S +P + R +++ +F + F G + Sbjct: 1381 KGFYTSFEDWGGKNC----KISSVQPICLDSFTGPRRRNQIHLFSEPQFQGHSQSFEETT 1436 Query: 127 PSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHH 169 + + S V G+WV + G QYVLE H+ Sbjct: 1437 SQID----DSFSTKSCRVSGGSWVVYDGENFTGNQYVLEEGHY 1475 Score = 61.2 bits (147), Expect = 5e-10 Identities = 45/181 (24%), Positives = 73/181 (40%), Gaps = 13/181 (7%) Query: 11 PWKMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQYILE 70 P K+V++ E + E ++ V +KV+ G W+ +E F+G LE Sbjct: 1021 PGKVVIYSEPDVSEKCIEVFSDIQDCSSWSLSPVILIKVVRGCWILYEQPNFEGHSIPLE 1080 Query: 71 RGEYPSWDAWG-GNTAYPAERLTSFRPAACA-------NHRDSRLTIFEQENFLGKKGEL 122 GE WG + E S +P ++R S + +F + LG Sbjct: 1081 EGELELSGLWGIEDILERHEEAESDKPVVIGSIRHVVQDYRVSHIDLFTEPEGLGILSSY 1140 Query: 123 SDDYPSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSH 182 DD +Q G + S VH G W+ + PG++G ++LE G+Y W + Sbjct: 1141 FDDTEEMQGFG-VMQKTCSMKVHWGTWLIYEEPGFQGVPFILE----PGEYPDLSFWDTE 1195 Query: 183 A 183 A Sbjct: 1196 A 1196 Score = 58.9 bits (141), Expect = 3e-09 Identities = 26/84 (30%), Positives = 52/84 (61%), Gaps = 6/84 (7%) Query: 14 MVVWDEDGFQGRRHEFTAECPSVLELGFET-VRSLKVLSGAWVGFEHAGFQGQQYILERG 72 +++++ + F+G++ E AE ++ LGF T +RS++V+ G WV +E+ ++G+Q++L Sbjct: 1504 IILFEREDFKGKKIELNAETVNLRSLGFNTQIRSVQVIGGIWVTYEYGSYRGRQFLLSPA 1563 Query: 73 EYPSWDAWGGNTAYPAERLTSFRP 96 E P+W + G ++ S RP Sbjct: 1564 EVPNWYEFSG-----CRQIGSLRP 1582 >gi|13377002 crystallin, gamma D [Homo sapiens] Length = 174 Score = 95.1 bits (235), Expect = 3e-20 Identities = 59/183 (32%), Positives = 98/183 (53%), Gaps = 16/183 (8%) Query: 13 KMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQYILERG 72 K+ ++++ GFQGR +E +++ P+ L+ S +V SG W+ +E + G QY L RG Sbjct: 3 KITLYEDRGFQGRHYECSSDHPN-LQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRRG 61 Query: 73 EYPSWDAWGGNTAYPAERLTSFRPAACANHRDS-RLTIFEQENFLGKKGELSDDYPSLQA 131 +Y W G + S R H S R+ ++E+E++ G+ E ++D LQ Sbjct: 62 DYADHQQWMGLS-------DSVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQD 114 Query: 132 MGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQVQSI 191 + NE+ S +V G+WV + YRG QY+L GDY+ +++WG A +V S+ Sbjct: 115 R-FRFNEIHSLNVLEGSWVLYELSNYRGRQYLL----MPGDYRRYQDWG--ATNARVGSL 167 Query: 192 RRI 194 RR+ Sbjct: 168 RRV 170 Score = 56.2 bits (134), Expect = 2e-08 Identities = 24/78 (30%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Query: 9 AGPWKMVVWDEDGFQGRRHEFTAECPSVLE-LGFETVRSLKVLSGAWVGFEHAGFQGQQY 67 +G ++ +++ + ++G+ EFT +C + + F + SL VL G+WV +E + ++G+QY Sbjct: 85 SGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNEIHSLNVLEGSWVLYELSNYRGRQY 144 Query: 68 ILERGEYPSWDAWGGNTA 85 +L G+Y + WG A Sbjct: 145 LLMPGDYRRYQDWGATNA 162 >gi|90403579 beta-gamma crystallin domain containing 3 [Homo sapiens] Length = 1022 Score = 88.6 bits (218), Expect = 3e-18 Identities = 61/189 (32%), Positives = 101/189 (53%), Gaps = 18/189 (9%) Query: 13 KMVVWDEDGFQGRRHEFTAECPSVLEL-----GFETVRSLKVLSGAWVGFEHAGFQGQQY 67 K++++++ F G+ EF+ SV F + S++V+ G WV +E F+GQQ+ Sbjct: 532 KVIIYEKPHFHGQAKEFSEHIDSVPNFLKNNGDFHRIGSIRVIGGVWVAYEKEHFKGQQF 591 Query: 68 ILERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGELSD-DY 126 +LE G++ +A G ++ + SFR AN +S +T+FE + GK ++++ + Sbjct: 592 LLEEGDFEDSNACGALSS----PILSFRYLQ-ANFIESSVTLFESDLESGKFIDITNQEI 646 Query: 127 PSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTF 186 L+ +G+ G++ S HV SG WV Q + G QY+LE G YK F +WG Sbjct: 647 SDLEEIGF-GSKTRSIHVKSGVWVAYQQKFFCGEQYILE----KGKYKCFFDWGGSNNI- 700 Query: 187 QVQSIRRIQ 195 + SIR IQ Sbjct: 701 -IMSIRPIQ 708 Score = 55.5 bits (132), Expect = 3e-08 Identities = 47/165 (28%), Positives = 73/165 (44%), Gaps = 14/165 (8%) Query: 32 ECPSVLELGFET-VRSLKVLSGAWVGFEHAGFQGQQYILERGEYPSWDAWGG-NTAYPAE 89 E + E+GF + RS+ V SG WV ++ F G+QYILE+G+Y + WGG N + Sbjct: 645 EISDLEEIGFGSKTRSIHVKSGVWVAYQQKFFCGEQYILEKGKYKCFFDWGGSNNIIMSI 704 Query: 90 RLTSFRPAACANHRDSRLTIFEQENFLGKKGELSDDYPSLQAMGWEGNEVGSFHVHSGAW 149 R P N L F + F G+ + +++ L ++ SF V G W Sbjct: 705 RPIQLEPLG-INEPPHLLKAFSKPGFQGECIDFTEETSDLTSL-----MPCSFKVLRGCW 758 Query: 150 VCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQVQSIRRI 194 + Y+ +V C G Y G P +V+S++ I Sbjct: 759 LLY----YQEDMFVNHCVLEEGLYADLTSCG--CPASKVKSLKPI 797 Score = 47.4 bits (111), Expect = 8e-06 Identities = 37/156 (23%), Positives = 64/156 (41%), Gaps = 20/156 (12%) Query: 34 PSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQYILERGEYPSWDAWGGNTAYPAERLTS 93 P++ EL S V SG W+ + F+GQ +LE G + S Sbjct: 463 PNLEELNISKSVSFTVKSGVWLAYPDINFKGQATVLEEDH--------GLFEISTAEMKS 514 Query: 94 FRPAACANHR-----DSRLTIFEQENFLGKKGELS---DDYPSLQAMGWEGNEVGSFHVH 145 P + + ++ I+E+ +F G+ E S D P+ + + +GS V Sbjct: 515 LHPLQMGGLKVEMPMNLKVIIYEKPHFHGQAKEFSEHIDSVPNFLKNNGDFHRIGSIRVI 574 Query: 146 SGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGS 181 G WV + ++G Q++LE GD++ G+ Sbjct: 575 GGVWVAYEKEHFKGQQFLLE----EGDFEDSNACGA 606 Score = 41.2 bits (95), Expect = 6e-04 Identities = 43/171 (25%), Positives = 70/171 (40%), Gaps = 11/171 (6%) Query: 2 TLQCTKSAGPWKMVVWD--EDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEH 59 TL+C G KMV++D E + + E P F +KV+ G W+ +E Sbjct: 339 TLRCNPRPG--KMVIYDLHESTY---KQEVYCNIPDATSWSFPNGVLIKVVRGCWILYEK 393 Query: 60 AGFQGQQYILERGEYPSWDAW-GGNTAYPAER-LTSFRPAACANHRDSRLTIFEQENFLG 117 F+GQ+ +LE GE W N +P + + + +F Q + Sbjct: 394 PHFRGQKCVLEEGEKVLNRDWILQNRRHPQRNFILGSLKRVLKDCSIPEIELFPQSDPAC 453 Query: 118 KKGELSDDYPSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDH 168 + P+L+ + ++ SF V SG W+ ++G VLE DH Sbjct: 454 CPVYIQRAVPNLEELNI--SKSVSFTVKSGVWLAYPDINFKGQATVLEEDH 502 Score = 37.4 bits (85), Expect = 0.008 Identities = 22/60 (36%), Positives = 33/60 (55%), Gaps = 3/60 (5%) Query: 23 QGRRHEFTAECPSVL--ELGFETVRSLKVLSGAWVGFEHAGFQGQQYILERGEYPSWDAW 80 +GR SVL +L F T +S+ V SG W+ +E + F G+Q +L E P+W A+ Sbjct: 815 EGRELHLEEAVNSVLNKDLHFYT-QSVWVKSGLWIAYEGSNFLGRQILLRPNEIPNWTAF 873 >gi|21389517 gammaN-crystallin [Homo sapiens] Length = 182 Score = 85.1 bits (209), Expect = 3e-17 Identities = 55/152 (36%), Positives = 79/152 (51%), Gaps = 9/152 (5%) Query: 13 KMVVWDEDGFQGRRHEFTAECPSVLELGF-ETVRSLKVLSGAWVGFEHAGFQGQQYILER 71 K+ +++ F G++ E +C + + GF V S+ V SGAWV F H F+GQQ+ILE Sbjct: 7 KITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEH 66 Query: 72 GEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGELSDDYPSLQA 131 G+YP + W + ++ + S RP + RL IFE NF G+ E +D P LQ+ Sbjct: 67 GDYPDFFRWNSH----SDHMGSCRPVG-MHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQS 121 Query: 132 MGWEGNEVGSFHVH--SGAWVCSQFPGYRGFQ 161 GW N V + V+ AW F G FQ Sbjct: 122 RGWVKNCVNTIKVYGDGAAWSPRSF-GAEDFQ 152 Score = 68.2 bits (165), Expect = 4e-12 Identities = 34/81 (41%), Positives = 48/81 (59%), Gaps = 5/81 (6%) Query: 103 RDSRLTIFEQENFLGKKGELSDDYPSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQY 162 R ++T++E ++F G+K E+ D + Q G+ N V S HV SGAWVC P +RG Q+ Sbjct: 4 RSGKITLYEGKHFTGQKLEVFGDCDNFQDRGFM-NRVNSIHVESGAWVCFNHPDFRGQQF 62 Query: 163 VLECDHHSGDYKHFREWGSHA 183 +LE GDY F W SH+ Sbjct: 63 ILE----HGDYPDFFRWNSHS 79 >gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens] Length = 963 Score = 28.1 bits (61), Expect = 5.0 Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 19/56 (33%) Query: 114 NFLGKKGELSDDYPSLQAMGWEG-----------NEVGSFHVHSGAWVCSQFPGYR 158 N LG KGE+++ Y L W G N+VG F SQF GY+ Sbjct: 350 NPLGMKGEIAEAYADLVKQAWSGHHRSIVPHVFKNKVGHF--------ASQFLGYQ 397 >gi|4826764 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1 precursor [Homo sapiens] Length = 307 Score = 27.3 bits (59), Expect = 8.5 Identities = 18/64 (28%), Positives = 25/64 (39%), Gaps = 8/64 (12%) Query: 87 PAERLTSFRPAACANHRDSRLTIFEQENFLGKKGELSDDYPSLQAMGWEGNEVGSFHVHS 146 P+ER+ S NH E FL + G L+ DY +L +HVH Sbjct: 149 PSERVLSDYTQVFYNHMQKHKPYPSIEEFLVRDGRLNVDYKALNR--------SLYHVHM 200 Query: 147 GAWV 150 W+ Sbjct: 201 QNWL 204 >gi|94721268 villin-like protein [Homo sapiens] Length = 856 Score = 27.3 bits (59), Expect = 8.5 Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 8/48 (16%) Query: 63 QGQQYILERGEYPS-WDAWGGNTAYPA-----ERLTSFRPA--ACANH 102 + ++ +LE E P W+A GG YP+ E + SF+P C++H Sbjct: 573 KNEETVLEGQEPPHFWEALGGRAPYPSNKRLPEEVPSFQPRLFECSSH 620 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.136 0.457 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,244,461 Number of Sequences: 37866 Number of extensions: 373933 Number of successful extensions: 759 Number of sequences better than 10.0: 20 Number of HSP's better than 10.0 without gapping: 17 Number of HSP's successfully gapped in prelim test: 3 Number of HSP's that attempted gapping in prelim test: 637 Number of HSP's gapped (non-prelim): 38 length of query: 196 length of database: 18,247,518 effective HSP length: 97 effective length of query: 99 effective length of database: 14,574,516 effective search space: 1442877084 effective search space used: 1442877084 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.